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Novel motif:87

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name:motif87_RCGCACWS

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0038007 netrin-activated signaling pathway 1.600587e-8
GO:0002074 extraocular skeletal muscle development 1.714743e-8
GO:0021903 rostrocaudal neural tube patterning 8.216173e-8
GO:0050746 regulation of lipoprotein metabolic process 8.860561e-8
GO:0019101 female somatic sex determination 1.089841e-7
GO:0042703 menstruation 1.089841e-7
GO:0021535 cell migration in hindbrain 1.540812e-7
GO:0021536 diencephalon development 2.169174e-7
GO:0090305 nucleic acid phosphodiester bond hydrolysis 2.486469e-7
GO:0014028 notochord formation 2.771629e-7
GO:2000097 regulation of smooth muscle cell-matrix adhesion 3.239800e-7
GO:0008635 activation of caspase activity by cytochrome c 4.844188e-7
GO:0070192 chromosome organization involved in meiosis 5.254200e-7
GO:0043301 negative regulation of leukocyte degranulation 6.274260e-7
GO:0035094 response to nicotine 7.542050e-7
GO:0010765 positive regulation of sodium ion transport 9.449853e-7
GO:0033057 multicellular organismal reproductive behavior 1.015634e-6
GO:0043305 negative regulation of mast cell degranulation 1.809796e-6
GO:0014806 smooth muscle hyperplasia 2.282681e-6
GO:0007288 sperm axoneme assembly 2.670066e-6
GO:0050703 interleukin-1 alpha secretion 2.855928e-6
GO:0000089 mitotic metaphase 3.229700e-6
GO:0009650 UV protection 3.668877e-6
GO:0071258 cellular response to gravity 3.848089e-6
GO:2000098 negative regulation of smooth muscle cell-matrix adhesion 3.848089e-6
GO:0061044 negative regulation of vascular wound healing 3.848089e-6
GO:0035491 positive regulation of leukotriene production involved in inflammatory response 3.848089e-6
GO:0007128 meiotic prophase I 3.918824e-6
GO:0033590 response to cobalamin 4.268985e-6
GO:0006117 acetaldehyde metabolic process 4.268985e-6
GO:0071460 cellular response to cell-matrix adhesion 4.290701e-6
GO:0007286 spermatid development 6.865742e-6
GO:0006473 protein acetylation 8.437376e-6
GO:0090102 cochlea development 8.699624e-6
GO:0050747 positive regulation of lipoprotein metabolic process 8.733199e-6
GO:0006475 internal protein amino acid acetylation 9.745147e-6
GO:0006383 transcription from RNA polymerase III promoter 9.928031e-6
GO:0003105 negative regulation of glomerular filtration 1.091634e-5
GO:0097045 phosphatidylserine exposure on blood platelet 1.115192e-5
GO:0006386 termination of RNA polymerase III transcription 1.137034e-5
GO:0006385 transcription elongation from RNA polymerase III promoter 1.137034e-5
GO:0055075 potassium ion homeostasis 1.186021e-5
GO:0070474 positive regulation of uterine smooth muscle contraction 1.251743e-5
GO:0048515 spermatid differentiation 1.308495e-5
GO:0022601 menstrual cycle phase 1.344543e-5
GO:0018205 peptidyl-lysine modification 1.377994e-5
GO:0010224 response to UV-B 1.560490e-5
GO:0021675 nerve development 1.765357e-5
GO:0007638 mechanosensory behavior 1.873261e-5
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 2.021706e-5
GO:0060033 anatomical structure regression 2.046639e-5
GO:0021603 cranial nerve formation 2.470948e-5
GO:0033683 nucleotide-excision repair, DNA incision 2.470948e-5
GO:0007129 synapsis 2.481418e-5
GO:0021877 forebrain neuron fate commitment 2.718575e-5
GO:0000413 protein peptidyl-prolyl isomerization 2.967479e-5
GO:0045760 positive regulation of action potential 2.968095e-5
GO:0021932 hindbrain radial glia guided cell migration 3.143746e-5
GO:0021879 forebrain neuron differentiation 3.292618e-5
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 3.429231e-5
GO:0009296 flagellum assembly 3.659001e-5
GO:0043491 protein kinase B signaling cascade 3.677974e-5
GO:0021559 trigeminal nerve development 3.728672e-5
GO:0014040 positive regulation of Schwann cell differentiation 3.904165e-5
GO:0043543 protein acylation 3.958221e-5
GO:0060850 regulation of transcription involved in cell fate commitment 4.070992e-5
GO:0002200 somatic diversification of immune receptors 4.198139e-5
GO:0010721 negative regulation of cell development 4.373903e-5
GO:0007130 synaptonemal complex assembly 4.747131e-5
GO:0046108 uridine metabolic process 5.224923e-5
GO:0018394 peptidyl-lysine acetylation 5.267081e-5
GO:0006308 DNA catabolic process 5.295723e-5
GO:0033233 regulation of protein sumoylation 5.418573e-5
GO:0007616 long-term memory 5.725978e-5
GO:0060591 chondroblast differentiation 5.733985e-5
GO:0009263 deoxyribonucleotide biosynthetic process 5.779498e-5
GO:0060035 notochord cell development 5.849022e-5
GO:0018393 internal peptidyl-lysine acetylation 5.882567e-5
GO:0045116 protein neddylation 5.939809e-5
GO:0007495 visceral mesoderm-endoderm interaction involved in midgut development 6.516652e-5
GO:0033235 positive regulation of protein sumoylation 6.523697e-5
GO:0042369 vitamin D catabolic process 6.975665e-5
GO:0051323 metaphase 7.161307e-5
GO:2000124 regulation of endocannabinoid signaling pathway 7.197392e-5
GO:0051324 prophase 7.215705e-5
GO:0060014 granulosa cell differentiation 7.275751e-5
GO:0021983 pituitary gland development 7.660335e-5
GO:0021545 cranial nerve development 7.780358e-5
GO:0006108 malate metabolic process 7.788523e-5
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 7.849926e-5
GO:0021892 cerebral cortex GABAergic interneuron differentiation 8.331473e-5
GO:0031223 auditory behavior 8.929221e-5
GO:0060596 mammary placode formation 9.458959e-5
GO:0019087 transformation of host cell by virus 1.033583e-4
GO:0042069 regulation of catecholamine metabolic process 1.067024e-4
GO:0006821 chloride transport 1.070438e-4
GO:0072148 epithelial cell fate commitment 1.094808e-4
GO:0045792 negative regulation of cell size 1.169424e-4
GO:0045471 response to ethanol 1.169835e-4
GO:2000465 regulation of glycogen (starch) synthase activity 1.170853e-4
GO:0051260 protein homooligomerization 1.289006e-4
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis 1.326817e-4
GO:0033151 V(D)J recombination 1.375170e-4
GO:0034442 regulation of lipoprotein oxidation 1.378737e-4
GO:0031017 exocrine pancreas development 1.383058e-4
GO:0008654 phospholipid biosynthetic process 1.432280e-4
GO:0007020 microtubule nucleation 1.449871e-4
GO:0014707 branchiomeric skeletal muscle development 1.525622e-4
GO:0021707 cerebellar granule cell differentiation 1.530815e-4
GO:0030852 regulation of granulocyte differentiation 1.556240e-4
GO:0060026 convergent extension 1.644819e-4
GO:0072592 oxygen metabolic process 1.665250e-4
GO:0021794 thalamus development 1.698279e-4
GO:0001661 conditioned taste aversion 1.702355e-4
GO:0021872 forebrain generation of neurons 1.742946e-4
GO:0045212 neurotransmitter receptor biosynthetic process 1.767602e-4
GO:0072355 histone H3-T3 phosphorylation 1.767602e-4
GO:0032223 negative regulation of synaptic transmission, cholinergic 1.767602e-4
GO:0021933 radial glia guided migration of cerebellar granule cell 1.767602e-4
GO:0007420 brain development 1.783472e-4
GO:0014037 Schwann cell differentiation 1.816135e-4
GO:0032411 positive regulation of transporter activity 1.863450e-4
GO:0006283 transcription-coupled nucleotide-excision repair 1.907748e-4
GO:0035261 external genitalia morphogenesis 2.001161e-4
GO:0032741 positive regulation of interleukin-18 production 2.016428e-4
GO:0009956 radial pattern formation 2.016428e-4
GO:0032464 positive regulation of protein homooligomerization 2.080032e-4
GO:0018208 peptidyl-proline modification 2.219834e-4
GO:0050768 negative regulation of neurogenesis 2.374818e-4
GO:0006788 heme oxidation 2.409851e-4
GO:0002886 regulation of myeloid leukocyte mediated immunity 2.415707e-4
GO:0016573 histone acetylation 2.481035e-4
GO:0048562 embryonic organ morphogenesis 2.537679e-4
GO:0021943 formation of radial glial scaffolds 2.582428e-4
GO:0031104 dendrite regeneration 2.668620e-4
GO:0010939 regulation of necrotic cell death 2.774449e-4
GO:0090031 positive regulation of steroid hormone biosynthetic process 2.787602e-4
GO:0003406 retinal pigment epithelium development 2.905460e-4
GO:0048842 positive regulation of axon extension involved in axon guidance 2.948121e-4
GO:0030574 collagen catabolic process 2.978369e-4
GO:0042552 myelination 3.044299e-4
GO:0045007 depurination 3.090811e-4
GO:0022011 myelination in peripheral nervous system 3.228761e-4
GO:0014014 negative regulation of gliogenesis 3.399148e-4
GO:0009265 2'-deoxyribonucleotide biosynthetic process 3.459905e-4
GO:0030262 apoptotic nuclear change 3.509831e-4
GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis 3.677841e-4
GO:0030917 midbrain-hindbrain boundary development 3.803750e-4
GO:0032007 negative regulation of TOR signaling cascade 3.807074e-4
GO:0021557 oculomotor nerve development 3.887627e-4
GO:0040018 positive regulation of multicellular organism growth 3.953987e-4
GO:0014044 Schwann cell development 4.005030e-4
GO:0050905 neuromuscular process 4.052115e-4
GO:0014038 regulation of Schwann cell differentiation 4.212240e-4
GO:0040040 thermosensory behavior 4.250474e-4
GO:0002069 columnar/cuboidal epithelial cell maturation 4.411721e-4
GO:0034470 ncRNA processing 4.431200e-4
GO:0001830 trophectodermal cell fate commitment 4.448302e-4
GO:0044335 canonical Wnt receptor signaling pathway involved in neural crest cell differentiation 4.448302e-4
GO:0030902 hindbrain development 4.457704e-4
GO:2000467 positive regulation of glycogen (starch) synthase activity 4.491230e-4
GO:0042053 regulation of dopamine metabolic process 4.720637e-4
GO:0021895 cerebral cortex neuron differentiation 4.776471e-4
GO:0070926 regulation of ATP:ADP antiporter activity 4.816598e-4
GO:0032774 RNA biosynthetic process 4.871460e-4
GO:0006351 transcription, DNA-dependent 4.871524e-4
GO:0006682 galactosylceramide biosynthetic process 5.029955e-4
GO:0007214 gamma-aminobutyric acid signaling pathway 5.349784e-4
GO:0018993 somatic sex determination 5.471648e-4
GO:0021511 spinal cord patterning 5.606198e-4
GO:0032971 regulation of muscle filament sliding 5.618887e-4
GO:0043966 histone H3 acetylation 5.638967e-4
GO:0035136 forelimb morphogenesis 5.638967e-4
GO:0009186 deoxyribonucleoside diphosphate metabolic process 5.754298e-4
GO:0042711 maternal behavior 5.777058e-4
GO:0033566 gamma-tubulin complex localization 5.865470e-4
GO:0060060 post-embryonic retina morphogenesis in camera-type eye 5.865470e-4
GO:0006384 transcription initiation from RNA polymerase III promoter 5.865470e-4
GO:0018872 arsonoacetate metabolic process 6.074206e-4
GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation 6.074206e-4
GO:0001514 selenocysteine incorporation 6.108896e-4
GO:0008588 release of cytoplasmic sequestered NF-kappaB 6.265050e-4
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 6.300502e-4
GO:0003310 pancreatic A cell differentiation 6.306260e-4
GO:0045022 early endosome to late endosome transport 6.486230e-4
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6.598921e-4
GO:0003016 respiratory system process 6.755597e-4
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 6.856611e-4
GO:0021854 hypothalamus development 6.856611e-4
GO:0043687 post-translational protein modification 6.894201e-4
GO:0048570 notochord morphogenesis 7.080642e-4
GO:0021861 forebrain radial glial cell differentiation 7.083343e-4
GO:0008366 axon ensheathment 7.371380e-4
GO:0060716 labyrinthine layer blood vessel development 7.398247e-4
GO:0046113 nucleobase catabolic process 7.586989e-4
GO:0042167 heme catabolic process 7.670979e-4
GO:0061034 olfactory bulb mitral cell layer development 7.783123e-4
GO:0071726 cellular response to diacyl bacterial lipopeptide 7.783123e-4
GO:0042496 detection of diacyl bacterial lipopeptide 7.783123e-4
GO:0070193 synaptonemal complex organization 7.885141e-4
GO:0000720 pyrimidine dimer repair by nucleotide-excision repair 8.067858e-4
GO:0030853 negative regulation of granulocyte differentiation 8.207800e-4
GO:0043313 regulation of neutrophil degranulation 8.312430e-4
GO:0021513 spinal cord dorsal/ventral patterning 8.576311e-4
GO:0018193 peptidyl-amino acid modification 8.593292e-4
GO:0071816 tail-anchored membrane protein insertion into ER membrane 8.680573e-4
GO:0015824 proline transport 9.198563e-4
GO:0032205 negative regulation of telomere maintenance 9.371564e-4
GO:0006927 transformed cell apoptosis 9.592865e-4
GO:0043585 nose morphogenesis 9.592865e-4
GO:0051534 negative regulation of NFAT protein import into nucleus 1.043678e-3
GO:0090370 negative regulation of cholesterol efflux 1.051543e-3
GO:0010980 positive regulation of vitamin D 24-hydroxylase activity 1.051543e-3
GO:0071169 establishment of protein localization to chromatin 1.054024e-3
GO:0090245 axis elongation involved in somitogenesis 1.061484e-3
GO:0021874 Wnt receptor signaling pathway involved in forebrain neuroblast division 1.061484e-3
GO:0071281 cellular response to iron ion 1.064484e-3
GO:0033687 osteoblast proliferation 1.174346e-3
GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein 1.174346e-3
GO:0019637 organophosphate metabolic process 1.180053e-3
GO:0016447 somatic recombination of immunoglobulin gene segments 1.194584e-3
GO:0000966 RNA 5'-end processing 1.203405e-3
GO:0032781 positive regulation of ATPase activity 1.208564e-3
GO:0021506 anterior neuropore closure 1.234195e-3
GO:0014916 regulation of lung blood pressure 1.234195e-3
GO:0032863 activation of Rac GTPase activity 1.236698e-3
GO:0035356 cellular triglyceride homeostasis 1.262630e-3
GO:0045799 positive regulation of chromatin assembly or disassembly 1.284144e-3
GO:0043633 polyadenylation-dependent RNA catabolic process 1.291106e-3
GO:0006235 dTTP biosynthetic process 1.329297e-3
GO:0051289 protein homotetramerization 1.371794e-3
GO:0000019 regulation of mitotic recombination 1.389968e-3
GO:0009448 gamma-aminobutyric acid metabolic process 1.394599e-3
GO:0032230 positive regulation of synaptic transmission, GABAergic 1.397867e-3
GO:0017121 phospholipid scrambling 1.415008e-3
GO:0030225 macrophage differentiation 1.416378e-3
GO:0045820 negative regulation of glycolysis 1.434627e-3
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.442436e-3
GO:0032661 regulation of interleukin-18 production 1.457744e-3
GO:0060021 palate development 1.459454e-3
GO:0048625 myoblast cell fate commitment 1.459912e-3
GO:0045444 fat cell differentiation 1.462597e-3
GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane 1.470390e-3
GO:0048790 maintenance of presynaptic active zone structure 1.470390e-3
GO:0048841 regulation of axon extension involved in axon guidance 1.482556e-3
GO:0030237 female sex determination 1.484362e-3
GO:0060253 negative regulation of glial cell proliferation 1.494801e-3
GO:0001300 chronological cell aging 1.503554e-3
GO:0050771 negative regulation of axonogenesis 1.524167e-3
GO:0071404 cellular response to low-density lipoprotein particle stimulus 1.567735e-3
GO:0046655 folic acid metabolic process 1.568803e-3
GO:0071727 cellular response to triacyl bacterial lipopeptide 1.570685e-3
GO:0042495 detection of triacyl bacterial lipopeptide 1.570685e-3
GO:0015840 urea transport 1.570685e-3
GO:0060073 micturition 1.734413e-3
GO:0002016 regulation of blood volume by renin-angiotensin 1.734413e-3
GO:0033084 regulation of immature T cell proliferation in thymus 1.734413e-3
GO:0050690 regulation of defense response to virus by virus 1.745302e-3
GO:0001508 regulation of action potential 1.753089e-3
GO:0042420 dopamine catabolic process 1.786290e-3
GO:0042472 inner ear morphogenesis 1.790571e-3
GO:0070914 UV-damage excision repair 1.793350e-3
GO:0010659 cardiac muscle cell apoptosis 1.795194e-3
GO:0014898 cardiac muscle hypertrophy in response to stress 1.832362e-3
GO:0009304 tRNA transcription 1.832362e-3
GO:0090231 regulation of spindle checkpoint 1.903447e-3
GO:0042471 ear morphogenesis 1.915106e-3
GO:0021683 cerebellar granular layer morphogenesis 1.932571e-3
GO:0090200 positive regulation of release of cytochrome c from mitochondria 1.954165e-3
GO:0060318 definitive erythrocyte differentiation 1.964903e-3
GO:0007417 central nervous system development 2.013206e-3
GO:0043064 flagellum organization 2.030199e-3
GO:0051099 positive regulation of binding 2.030610e-3
GO:0021537 telencephalon development 2.031048e-3
GO:0043314 negative regulation of neutrophil degranulation 2.077894e-3
GO:0070593 dendrite self-avoidance 2.086030e-3
GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production 2.087320e-3
GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway 2.087320e-3
GO:0032738 positive regulation of interleukin-15 production 2.087320e-3
GO:0030322 stabilization of membrane potential 2.118603e-3
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway 2.118603e-3
GO:0010940 positive regulation of necrotic cell death 2.120785e-3
GO:0003417 growth plate cartilage development 2.120785e-3
GO:0060384 innervation 2.157900e-3
GO:0010960 magnesium ion homeostasis 2.184561e-3
GO:0050748 negative regulation of lipoprotein metabolic process 2.208739e-3
GO:0016445 somatic diversification of immunoglobulins 2.221661e-3
GO:0033092 positive regulation of immature T cell proliferation in thymus 2.232578e-3
GO:0010467 gene expression 2.243900e-3
GO:0090311 regulation of protein deacetylation 2.258922e-3
GO:0007619 courtship behavior 2.262983e-3
GO:2000171 negative regulation of dendrite development 2.328240e-3
GO:0021532 neural tube patterning 2.342848e-3
GO:0021562 vestibulocochlear nerve development 2.375941e-3
GO:0060179 male mating behavior 2.378128e-3
GO:0030223 neutrophil differentiation 2.384174e-3
GO:0048320 axial mesoderm formation 2.398168e-3
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion 2.414146e-3
GO:0008045 motor axon guidance 2.447485e-3
GO:0048663 neuron fate commitment 2.473026e-3
GO:2000151 negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 2.474239e-3
GO:2000164 negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis 2.474239e-3
GO:2000168 negative regulation of planar cell polarity pathway involved in neural tube closure 2.474239e-3
GO:2000166 negative regulation of planar cell polarity pathway involved in pericardium morphogenesis 2.474239e-3
GO:2000162 negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis 2.474239e-3
GO:0000917 barrier septum formation 2.474239e-3
GO:2000149 negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis 2.474239e-3
GO:0021586 pons maturation 2.474239e-3
GO:2000055 positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 2.474239e-3
GO:0061310 canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development 2.474239e-3
GO:0006644 phospholipid metabolic process 2.484383e-3
GO:0042730 fibrinolysis 2.496599e-3
GO:0060083 smooth muscle contraction involved in micturition 2.557878e-3
GO:0060381 positive regulation of single-stranded telomeric DNA binding 2.656673e-3
GO:0032509 endosome transport via multivesicular body sorting pathway 2.665068e-3
GO:0018958 phenol-containing compound metabolic process 2.668239e-3
GO:0003093 regulation of glomerular filtration 2.720096e-3
GO:0007549 dosage compensation 2.720096e-3
GO:0000389 nuclear mRNA 3'-splice site recognition 2.720096e-3
GO:0006289 nucleotide-excision repair 2.733152e-3
GO:0033152 immunoglobulin V(D)J recombination 2.739314e-3
GO:0002543 activation of blood coagulation via clotting cascade 2.797334e-3
GO:0060465 pharynx development 2.846440e-3
GO:0042942 D-serine transport 2.846440e-3
GO:0060611 mammary gland fat development 2.938887e-3
GO:0043461 proton-transporting ATP synthase complex assembly 2.938887e-3
GO:0060438 trachea development 2.940115e-3
GO:0006382 adenosine to inosine editing 2.964947e-3
GO:2000651 positive regulation of sodium ion transmembrane transporter activity 2.964947e-3
GO:2000627 positive regulation of miRNA catabolic process 2.998438e-3
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process 2.998438e-3
GO:0050955 thermoception 2.998438e-3
GO:0000964 mitochondrial RNA 5'-end processing 2.998438e-3
GO:0043388 positive regulation of DNA binding 3.027219e-3
GO:0007635 chemosensory behavior 3.030284e-3
GO:0019226 transmission of nerve impulse 3.055741e-3
GO:0051891 positive regulation of cardioblast differentiation 3.084628e-3
GO:0045638 negative regulation of myeloid cell differentiation 3.087048e-3
GO:0032185 septin cytoskeleton organization 3.096483e-3
GO:0043467 regulation of generation of precursor metabolites and energy 3.182913e-3
GO:0030851 granulocyte differentiation 3.187937e-3
GO:0006781 succinyl-CoA pathway 3.191384e-3
GO:0042747 circadian sleep/wake cycle, REM sleep 3.191384e-3
GO:0042450 arginine biosynthetic process via ornithine 3.191384e-3
GO:0030150 protein import into mitochondrial matrix 3.201558e-3
GO:0001672 regulation of chromatin assembly or disassembly 3.222836e-3
GO:0034776 response to histamine 3.223429e-3
GO:0071422 succinate transmembrane transport 3.223429e-3
GO:0008216 spermidine metabolic process 3.223429e-3
GO:0007623 circadian rhythm 3.288257e-3
GO:0006290 pyrimidine dimer repair 3.302071e-3
GO:0021636 trigeminal nerve morphogenesis 3.313900e-3
GO:0003014 renal system process 3.419691e-3
GO:0016197 endosome transport 3.439822e-3
GO:0035456 response to interferon-beta 3.466797e-3
GO:0043300 regulation of leukocyte degranulation 3.495674e-3
GO:0070340 detection of bacterial lipopeptide 3.524895e-3
GO:0035928 rRNA import into mitochondrion 3.524895e-3
GO:0045686 negative regulation of glial cell differentiation 3.534309e-3
GO:0002769 natural killer cell inhibitory signaling pathway 3.541948e-3
GO:0032409 regulation of transporter activity 3.547457e-3
GO:0035873 lactate transmembrane transport 3.600832e-3
GO:0060301 positive regulation of cytokine activity 3.647276e-3
GO:0042249 establishment of planar polarity of embryonic epithelium 3.647276e-3
GO:0009443 pyridoxal 5'-phosphate salvage 3.708243e-3
GO:0016233 telomere capping 3.728878e-3
GO:0003181 atrioventricular valve morphogenesis 3.754651e-3
GO:0021602 cranial nerve morphogenesis 3.825285e-3
GO:0042417 dopamine metabolic process 3.826827e-3
GO:0046500 S-adenosylmethionine metabolic process 3.847344e-3
GO:0003416 endochondral bone growth 3.848464e-3
GO:0042886 amide transport 3.848464e-3
GO:0008355 olfactory learning 3.898688e-3
GO:0001507 acetylcholine catabolic process in synaptic cleft 3.898688e-3
GO:0042093 T-helper cell differentiation 3.964202e-3
GO:0007270 neuron-neuron synaptic transmission 3.966450e-3
GO:0007386 compartment pattern specification 3.991467e-3
GO:0072529 pyrimidine-containing compound catabolic process 4.018357e-3
GO:0045920 negative regulation of exocytosis 4.049334e-3
GO:0032926 negative regulation of activin receptor signaling pathway 4.099021e-3
GO:0043534 blood vessel endothelial cell migration 4.122152e-3
GO:0055098 response to low-density lipoprotein particle stimulus 4.176855e-3
GO:0006208 pyrimidine base catabolic process 4.178550e-3
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway 4.180459e-3
GO:0045556 positive regulation of TRAIL biosynthetic process 4.285511e-3
GO:0021623 oculomotor nerve formation 4.300737e-3
GO:0051382 kinetochore assembly 4.300737e-3
GO:0003409 optic cup structural organization 4.300737e-3
GO:0003404 optic vesicle morphogenesis 4.300737e-3
GO:0032414 positive regulation of ion transmembrane transporter activity 4.303131e-3
GO:0071276 cellular response to cadmium ion 4.363677e-3
GO:0060839 endothelial cell fate commitment 4.363677e-3
GO:0010626 negative regulation of Schwann cell proliferation 4.363677e-3
GO:0016045 detection of bacterium 4.367888e-3
GO:0021697 cerebellar cortex formation 4.428426e-3
GO:0071899 negative regulation of estrogen receptor binding 4.474843e-3
GO:0003285 septum secundum development 4.502290e-3
GO:0010701 positive regulation of norepinephrine secretion 4.509209e-3
GO:0021517 ventral spinal cord development 4.510574e-3
GO:0032376 positive regulation of cholesterol transport 4.511451e-3
GO:0034080 CenH3-containing nucleosome assembly at centromere 4.512661e-3
GO:0048486 parasympathetic nervous system development 4.512661e-3
GO:0006659 phosphatidylserine biosynthetic process 4.523503e-3
GO:0015747 urate transport 4.589928e-3
GO:2000772 regulation of cellular senescence 4.630915e-3
GO:0051898 negative regulation of protein kinase B signaling cascade 4.634573e-3
GO:0060019 radial glial cell differentiation 4.638387e-3
GO:0032648 regulation of interferon-beta production 4.691191e-3
GO:0070537 histone H2A K63-linked deubiquitination 4.694285e-3
GO:0010452 histone H3-K36 methylation 4.752022e-3
GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process 5.010445e-3
GO:0003278 apoptosis involved in heart morphogenesis 5.010445e-3
GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment 5.075455e-3
GO:0006575 cellular modified amino acid metabolic process 5.203936e-3
GO:0006357 regulation of transcription from RNA polymerase II promoter 5.311840e-3
GO:0022007 convergent extension involved in neural plate elongation 5.312142e-3
GO:0032481 positive regulation of type I interferon production 5.386183e-3
GO:0022898 regulation of transmembrane transporter activity 5.417556e-3
GO:0009151 purine deoxyribonucleotide metabolic process 5.435637e-3
GO:0008306 associative learning 5.438412e-3
GO:0030221 basophil differentiation 5.451227e-3
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter 5.486057e-3
GO:0021905 forebrain-midbrain boundary formation 5.594391e-3
GO:0021918 regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment 5.594391e-3
GO:0021902 commitment of neuronal cell to specific neuron type in forebrain 5.594391e-3
GO:0003322 pancreatic A cell development 5.594391e-3
GO:0015820 leucine transport 5.634069e-3
GO:0046498 S-adenosylhomocysteine metabolic process 5.657676e-3
GO:0006083 acetate metabolic process 5.686389e-3
GO:0010587 miRNA catabolic process 5.686389e-3
GO:0043029 T cell homeostasis 5.777682e-3
GO:0046628 positive regulation of insulin receptor signaling pathway 5.791889e-3
GO:0007588 excretion 5.850237e-3
GO:0033147 negative regulation of estrogen receptor signaling pathway 5.981980e-3
GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity 5.981980e-3
GO:0060166 olfactory pit development 5.989812e-3
GO:0003062 regulation of heart rate by chemical signal 5.989812e-3
GO:0048665 neuron fate specification 6.019664e-3
GO:0032764 negative regulation of mast cell cytokine production 6.062659e-3
GO:0006463 steroid hormone receptor complex assembly 6.177055e-3
GO:0021783 preganglionic parasympathetic nervous system development 6.179107e-3
GO:0090342 regulation of cell aging 6.197003e-3
GO:0001970 positive regulation of activation of membrane attack complex 6.240430e-3
GO:0050819 negative regulation of coagulation 6.263183e-3
GO:0042416 dopamine biosynthetic process 6.327298e-3
GO:0016180 snRNA processing 6.346593e-3
GO:0042312 regulation of vasodilation 6.352142e-3
GO:0061037 negative regulation of cartilage development 6.387312e-3
GO:0071402 cellular response to lipoprotein particle stimulus 6.387312e-3
GO:0017187 peptidyl-glutamic acid carboxylation 6.453752e-3
GO:0021797 forebrain anterior/posterior pattern specification 6.480641e-3
GO:0021681 cerebellar granular layer development 6.491982e-3
GO:0060306 regulation of membrane repolarization 6.592028e-3
GO:0021514 ventral spinal cord interneuron differentiation 6.593018e-3
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 6.593390e-3
GO:0002642 positive regulation of immunoglobulin biosynthetic process 6.652903e-3
GO:0010983 positive regulation of high-density lipoprotein particle clearance 6.652903e-3
GO:0060464 lung lobe formation 6.703347e-3
GO:0071800 podosome assembly 6.703347e-3
GO:0009235 cobalamin metabolic process 6.703347e-3
GO:0042537 benzene-containing compound metabolic process 6.703753e-3
GO:0019264 glycine biosynthetic process from serine 6.770894e-3
GO:0009189 deoxyribonucleoside diphosphate biosynthetic process 6.770894e-3
GO:0046886 positive regulation of hormone biosynthetic process 6.788448e-3
GO:0014832 urinary bladder smooth muscle contraction 6.805319e-3
GO:0010811 positive regulation of cell-substrate adhesion 6.894834e-3
GO:0010034 response to acetate 6.949181e-3
GO:0021533 cell differentiation in hindbrain 7.044352e-3
GO:0006173 dADP biosynthetic process 7.051650e-3
GO:0015734 taurine transport 7.051650e-3
GO:0035129 post-embryonic hindlimb morphogenesis 7.172700e-3
GO:0018230 peptidyl-L-cysteine S-palmitoylation 7.172700e-3
GO:0006746 FADH2 metabolic process 7.172700e-3
GO:0051101 regulation of DNA binding 7.212751e-3
GO:0035767 endothelial cell chemotaxis 7.213494e-3
GO:0051532 regulation of NFAT protein import into nucleus 7.236644e-3
GO:0014909 smooth muscle cell migration 7.294859e-3
GO:0043967 histone H4 acetylation 7.341283e-3
GO:0035082 axoneme assembly 7.352007e-3
GO:0033327 Leydig cell differentiation 7.356778e-3
GO:0032461 positive regulation of protein oligomerization 7.371212e-3
GO:0021555 midbrain-hindbrain boundary morphogenesis 7.398816e-3
GO:0060406 positive regulation of penile erection 7.398816e-3
GO:0021761 limbic system development 7.427905e-3
GO:0006809 nitric oxide biosynthetic process 7.481538e-3
GO:0009744 response to sucrose stimulus 7.496842e-3
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway 7.516640e-3
GO:0006268 DNA unwinding involved in replication 7.516640e-3
GO:0006487 protein N-linked glycosylation 7.563188e-3
GO:0042823 pyridoxal phosphate biosynthetic process 7.566734e-3
GO:0019228 regulation of action potential in neuron 7.730497e-3
GO:0060764 cell-cell signaling involved in mammary gland development 7.763187e-3
GO:0021696 cerebellar cortex morphogenesis 7.777960e-3
GO:0021952 central nervous system projection neuron axonogenesis 7.865494e-3
GO:0090103 cochlea morphogenesis 7.871313e-3
GO:0021798 forebrain dorsal/ventral pattern formation 7.935849e-3
GO:0021587 cerebellum morphogenesis 8.037074e-3
GO:0035725 sodium ion transmembrane transport 8.056702e-3
GO:0017004 cytochrome complex assembly 8.190345e-3
GO:0070172 positive regulation of tooth mineralization 8.232241e-3


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0006139 nucleobase-containing compound metabolic process 1.281916e-13
GO:0044260 cellular macromolecule metabolic process 1.718884e-12
GO:0030488 tRNA methylation 1.463100e-11
GO:0010467 gene expression 2.460171e-11
GO:0016070 RNA metabolic process 2.636615e-11
GO:0090304 nucleic acid metabolic process 6.345604e-11
GO:0034641 cellular nitrogen compound metabolic process 1.826068e-10
GO:0006807 nitrogen compound metabolic process 1.388301e-9
GO:0032465 regulation of cytokinesis 1.405173e-9
GO:0032467 positive regulation of cytokinesis 4.763529e-9
GO:0032774 RNA biosynthetic process 5.149999e-9
GO:0008033 tRNA processing 6.437773e-9
GO:0043170 macromolecule metabolic process 7.687860e-9
GO:0044237 cellular metabolic process 9.860189e-9
GO:0006351 transcription, DNA-dependent 1.036565e-8
GO:0006400 tRNA modification 1.813981e-8
GO:0034614 cellular response to reactive oxygen species 3.113785e-8
GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine 5.147024e-8
GO:0051301 cell division 6.180686e-8
GO:0006779 porphyrin-containing compound biosynthetic process 6.636600e-8
GO:0055090 acylglycerol homeostasis 7.527995e-8
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 1.280123e-7
GO:0051890 regulation of cardioblast differentiation 1.342906e-7
GO:0071777 positive regulation of cell cycle cytokinesis 2.331043e-7
GO:0006783 heme biosynthetic process 2.647003e-7
GO:0035886 vascular smooth muscle cell differentiation 3.172631e-7
GO:0044238 primary metabolic process 3.806056e-7
GO:0019219 regulation of nucleobase-containing compound metabolic process 5.018926e-7
GO:0060575 intestinal epithelial cell differentiation 6.206279e-7
GO:0051171 regulation of nitrogen compound metabolic process 7.663784e-7
GO:0018202 peptidyl-histidine modification 9.708052e-7
GO:0051302 regulation of cell division 9.753220e-7
GO:0060440 trachea formation 1.206336e-6
GO:0060439 trachea morphogenesis 1.244517e-6
GO:0044249 cellular biosynthetic process 1.508801e-6
GO:0034645 cellular macromolecule biosynthetic process 1.758077e-6
GO:0006399 tRNA metabolic process 1.809596e-6
GO:0042168 heme metabolic process 1.821578e-6
GO:0090084 negative regulation of inclusion body assembly 3.670739e-6
GO:0002065 columnar/cuboidal epithelial cell differentiation 3.838857e-6
GO:0006778 porphyrin-containing compound metabolic process 4.163762e-6
GO:0035137 hindlimb morphogenesis 4.336975e-6
GO:0051781 positive regulation of cell division 4.605528e-6
GO:0008344 adult locomotory behavior 5.153067e-6
GO:0006355 regulation of transcription, DNA-dependent 5.326805e-6
GO:0009059 macromolecule biosynthetic process 5.486987e-6
GO:0001510 RNA methylation 5.607103e-6
GO:0009058 biosynthetic process 5.974163e-6
GO:0090086 negative regulation of protein deubiquitination 7.718065e-6
GO:0031326 regulation of cellular biosynthetic process 8.640983e-6
GO:0030902 hindbrain development 1.164266e-5
GO:0051252 regulation of RNA metabolic process 1.513465e-5
GO:0070301 cellular response to hydrogen peroxide 1.538226e-5
GO:0007224 smoothened signaling pathway 1.633105e-5
GO:0034470 ncRNA processing 1.637881e-5
GO:0048384 retinoic acid receptor signaling pathway 1.662611e-5
GO:0070588 calcium ion transmembrane transport 1.680690e-5
GO:0033013 tetrapyrrole metabolic process 1.780197e-5
GO:0006982 response to lipid hydroperoxide 1.787424e-5
GO:0060433 bronchus development 2.055499e-5
GO:2000112 regulation of cellular macromolecule biosynthetic process 2.244741e-5
GO:0009451 RNA modification 2.246129e-5
GO:0002663 positive regulation of B cell tolerance induction 2.259339e-5
GO:0009889 regulation of biosynthetic process 2.267361e-5
GO:0001570 vasculogenesis 2.461306e-5
GO:0061036 positive regulation of cartilage development 2.695612e-5
GO:0030520 estrogen receptor signaling pathway 2.919024e-5
GO:0022038 corpus callosum development 3.418416e-5
GO:0006390 transcription from mitochondrial promoter 3.864965e-5
GO:0060164 regulation of timing of neuron differentiation 3.952966e-5
GO:0070327 thyroid hormone transport 4.152975e-5
GO:0007628 adult walking behavior 4.450197e-5
GO:0030534 adult behavior 4.459789e-5
GO:0007420 brain development 4.520968e-5
GO:0060010 Sertoli cell fate commitment 4.538995e-5
GO:0043461 proton-transporting ATP synthase complex assembly 4.731276e-5
GO:0007256 activation of JNKK activity 4.838085e-5
GO:0006713 glucocorticoid catabolic process 4.902833e-5
GO:0051891 positive regulation of cardioblast differentiation 5.338628e-5
GO:0001706 endoderm formation 5.429678e-5
GO:0031323 regulation of cellular metabolic process 6.747645e-5
GO:0032862 activation of Rho GTPase activity 7.948260e-5
GO:0006261 DNA-dependent DNA replication 8.008945e-5
GO:0046426 negative regulation of JAK-STAT cascade 8.149324e-5
GO:0048554 positive regulation of metalloenzyme activity 8.378870e-5
GO:0065005 protein-lipid complex assembly 8.819913e-5
GO:0000959 mitochondrial RNA metabolic process 9.026795e-5
GO:0060438 trachea development 1.014864e-4
GO:0060319 primitive erythrocyte differentiation 1.082460e-4
GO:0046102 inosine metabolic process 1.213989e-4
GO:0021517 ventral spinal cord development 1.335691e-4
GO:0071585 detoxification of cadmium ion 1.348030e-4
GO:0009987 cellular process 1.366704e-4
GO:0032856 activation of Ras GTPase activity 1.374835e-4
GO:0060795 cell fate commitment involved in formation of primary germ layers 1.404359e-4
GO:0002053 positive regulation of mesenchymal cell proliferation 1.423198e-4
GO:0060947 cardiac vascular smooth muscle cell differentiation 1.429498e-4
GO:0008152 metabolic process 1.474718e-4
GO:0018193 peptidyl-amino acid modification 1.496351e-4
GO:0007398 ectoderm development 1.498264e-4
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 1.621769e-4
GO:0002227 innate immune response in mucosa 1.680682e-4
GO:0042697 menopause 1.758960e-4
GO:0061113 pancreas morphogenesis 1.789054e-4
GO:0010556 regulation of macromolecule biosynthetic process 1.926897e-4
GO:0046501 protoporphyrinogen IX metabolic process 1.929050e-4
GO:0051148 negative regulation of muscle cell differentiation 1.969321e-4
GO:0003349 epicardium-derived cardiac endothelial cell differentiation 2.034916e-4
GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation 2.034916e-4
GO:0002651 positive regulation of tolerance induction to self antigen 2.089260e-4
GO:0034379 very-low-density lipoprotein particle assembly 2.163094e-4
GO:0070328 triglyceride homeostasis 2.178152e-4
GO:0001709 cell fate determination 2.231729e-4
GO:0070838 divalent metal ion transport 2.430774e-4
GO:0035116 embryonic hindlimb morphogenesis 2.500523e-4
GO:0050807 regulation of synapse organization 2.522433e-4
GO:0010468 regulation of gene expression 2.585031e-4
GO:0048511 rhythmic process 2.647113e-4
GO:0021756 striatum development 2.680423e-4
GO:0072511 divalent inorganic cation transport 2.709822e-4
GO:0048645 organ formation 2.952502e-4
GO:0031914 negative regulation of synaptic plasticity 2.972816e-4
GO:0010722 regulation of ferrochelatase activity 2.972816e-4
GO:0060216 definitive hemopoiesis 3.020129e-4
GO:0010982 regulation of high-density lipoprotein particle clearance 3.051537e-4
GO:0060375 regulation of mast cell differentiation 3.051537e-4
GO:0021987 cerebral cortex development 3.345623e-4
GO:0045686 negative regulation of glial cell differentiation 3.445250e-4
GO:0032259 methylation 3.521189e-4
GO:0006396 RNA processing 3.712479e-4
GO:0090361 regulation of platelet-derived growth factor production 3.760155e-4
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis 3.779588e-4
GO:0032606 type I interferon production 3.853909e-4
GO:0008054 cyclin catabolic process 3.853909e-4
GO:0043491 protein kinase B signaling cascade 3.879987e-4
GO:0060591 chondroblast differentiation 3.912589e-4
GO:0003136 negative regulation of heart induction by canonical Wnt receptor signaling pathway 3.987163e-4
GO:0001514 selenocysteine incorporation 3.987163e-4
GO:0002575 basophil chemotaxis 3.987163e-4
GO:0021954 central nervous system neuron development 4.010503e-4
GO:0048333 mesodermal cell differentiation 4.064216e-4
GO:0034660 ncRNA metabolic process 4.086131e-4
GO:0072337 modified amino acid transport 4.111763e-4
GO:0090085 regulation of protein deubiquitination 4.156824e-4
GO:0046591 embryonic leg joint morphogenesis 4.156824e-4
GO:0034616 response to laminar fluid shear stress 4.261237e-4
GO:2000736 regulation of stem cell differentiation 4.284405e-4
GO:0021562 vestibulocochlear nerve development 4.296158e-4
GO:0040032 post-embryonic body morphogenesis 4.336794e-4
GO:0015969 guanosine tetraphosphate metabolic process 4.700569e-4
GO:0071169 establishment of protein localization to chromatin 4.700569e-4
GO:0040015 negative regulation of multicellular organism growth 4.727609e-4
GO:2000741 positive regulation of mesenchymal stem cell differentiation 4.838353e-4
GO:0055091 phospholipid homeostasis 4.838353e-4
GO:0001824 blastocyst development 4.912011e-4
GO:0034599 cellular response to oxidative stress 5.096951e-4
GO:0010799 regulation of peptidyl-threonine phosphorylation 5.315174e-4
GO:0001710 mesodermal cell fate commitment 5.345996e-4
GO:0001704 formation of primary germ layer 5.353445e-4
GO:0009067 aspartate family amino acid biosynthetic process 5.438304e-4
GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 5.486204e-4
GO:0000722 telomere maintenance via recombination 5.636762e-4
GO:0001522 pseudouridine synthesis 5.641535e-4
GO:0008306 associative learning 5.711840e-4
GO:0051963 regulation of synapse assembly 6.024640e-4
GO:0080090 regulation of primary metabolic process 6.039898e-4
GO:0010896 regulation of triglyceride catabolic process 6.106116e-4
GO:0035136 forelimb morphogenesis 6.248966e-4
GO:0014054 positive regulation of gamma-aminobutyric acid secretion 6.274408e-4
GO:0007498 mesoderm development 6.279725e-4
GO:0032321 positive regulation of Rho GTPase activity 6.329649e-4
GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 6.532209e-4
GO:0033151 V(D)J recombination 6.567139e-4
GO:0045944 positive regulation of transcription from RNA polymerase II promoter 6.603561e-4
GO:0021953 central nervous system neuron differentiation 6.691314e-4
GO:0060644 mammary gland epithelial cell differentiation 6.735494e-4
GO:0006816 calcium ion transport 7.004035e-4
GO:0051005 negative regulation of lipoprotein lipase activity 7.042436e-4
GO:0072079 nephron tubule formation 7.055820e-4
GO:0007067 mitosis 7.072000e-4
GO:0046103 inosine biosynthetic process 7.177803e-4
GO:0060971 embryonic heart tube left/right pattern formation 7.177803e-4
GO:0008208 C21-steroid hormone catabolic process 7.177803e-4
GO:0006391 transcription initiation from mitochondrial promoter 7.177803e-4
GO:0006154 adenosine catabolic process 7.177803e-4
GO:0048665 neuron fate specification 7.221185e-4
GO:0007626 locomotory behavior 7.376649e-4
GO:0031398 positive regulation of protein ubiquitination 8.032461e-4
GO:0021781 glial cell fate commitment 8.247153e-4
GO:0044240 multicellular organismal lipid catabolic process 8.256835e-4
GO:0000086 G2/M transition of mitotic cell cycle 8.401964e-4
GO:0034220 ion transmembrane transport 8.558194e-4
GO:0060296 regulation of cilium beat frequency involved in ciliary motility 8.600429e-4
GO:0033092 positive regulation of immature T cell proliferation in thymus 8.600429e-4
GO:0032509 endosome transport via multivesicular body sorting pathway 8.693243e-4
GO:0019230 proprioception 8.693243e-4
GO:0031508 centromeric heterochromatin formation 8.893847e-4
GO:0018283 iron incorporation into metallo-sulfur cluster 9.021193e-4
GO:0060073 micturition 9.115390e-4
GO:0033136 serine phosphorylation of STAT3 protein 9.186302e-4
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway 9.186302e-4
GO:0006688 glycosphingolipid biosynthetic process 9.485545e-4
GO:0046543 development of secondary female sexual characteristics 9.734743e-4
GO:0090281 negative regulation of calcium ion import 9.945757e-4
GO:0007196 inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway 9.945757e-4
GO:0071584 negative regulation of zinc ion import 9.945757e-4
GO:0045165 cell fate commitment 1.014587e-3
GO:0055024 regulation of cardiac muscle tissue development 1.038320e-3
GO:0072141 renal interstitial cell development 1.050057e-3
GO:0021549 cerebellum development 1.061184e-3
GO:0048266 behavioral response to pain 1.121695e-3
GO:0000087 M phase of mitotic cell cycle 1.148550e-3
GO:0021571 rhombomere 5 development 1.155207e-3
GO:0070574 cadmium ion transmembrane transport 1.155207e-3
GO:0097084 vascular smooth muscle cell development 1.191846e-3
GO:0010452 histone H3-K36 methylation 1.191846e-3
GO:0006207 'de novo' pyrimidine base biosynthetic process 1.191846e-3
GO:0032801 receptor catabolic process 1.201777e-3
GO:0003310 pancreatic A cell differentiation 1.202824e-3
GO:0031576 G2/M transition checkpoint 1.235150e-3
GO:0071241 cellular response to inorganic substance 1.243345e-3
GO:0043117 positive regulation of vascular permeability 1.266221e-3
GO:0018205 peptidyl-lysine modification 1.267807e-3
GO:0016570 histone modification 1.283617e-3
GO:0072078 nephron tubule morphogenesis 1.298382e-3
GO:0072190 ureter urothelium development 1.321715e-3
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 1.328313e-3
GO:0043414 macromolecule methylation 1.343799e-3
GO:0051188 cofactor biosynthetic process 1.345377e-3
GO:0007403 glial cell fate determination 1.381757e-3
GO:2000688 positive regulation of rubidium ion transmembrane transporter activity 1.404688e-3
GO:0046604 positive regulation of mitotic centrosome separation 1.404688e-3
GO:2000682 positive regulation of rubidium ion transport 1.404688e-3
GO:0019556 histidine catabolic process to glutamate and formamide 1.404688e-3
GO:0035826 rubidium ion transport 1.404688e-3
GO:0035621 ER to Golgi ceramide transport 1.416464e-3
GO:0032232 negative regulation of actin filament bundle assembly 1.436268e-3
GO:0060038 cardiac muscle cell proliferation 1.441815e-3
GO:0033084 regulation of immature T cell proliferation in thymus 1.447443e-3
GO:0008211 glucocorticoid metabolic process 1.475704e-3
GO:0048505 regulation of timing of cell differentiation 1.479025e-3
GO:0034501 protein localization to kinetochore 1.489859e-3
GO:0030828 positive regulation of cGMP biosynthetic process 1.489859e-3
GO:0009086 methionine biosynthetic process 1.499376e-3
GO:0061047 positive regulation of branching involved in lung morphogenesis 1.499689e-3
GO:0061154 endothelial tube morphogenesis 1.499689e-3
GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development 1.499689e-3
GO:0044267 cellular protein metabolic process 1.505756e-3
GO:0022037 metencephalon development 1.523503e-3
GO:0042699 follicle-stimulating hormone signaling pathway 1.533474e-3
GO:0060419 heart growth 1.540494e-3
GO:0048389 intermediate mesoderm development 1.616829e-3
GO:0072098 anterior/posterior pattern specification involved in kidney development 1.616829e-3
GO:0061333 renal tubule morphogenesis 1.619497e-3
GO:0034442 regulation of lipoprotein oxidation 1.643271e-3
GO:0051004 regulation of lipoprotein lipase activity 1.648466e-3
GO:0007612 learning 1.657409e-3
GO:0048745 smooth muscle tissue development 1.682004e-3
GO:0006284 base-excision repair 1.682599e-3
GO:0046373 L-arabinose metabolic process 1.705136e-3
GO:0046130 purine ribonucleoside catabolic process 1.709667e-3
GO:0061088 regulation of sequestering of zinc ion 1.728549e-3
GO:0007610 behavior 1.764395e-3
GO:0016569 covalent chromatin modification 1.809547e-3
GO:0060979 vasculogenesis involved in coronary vascular morphogenesis 1.817795e-3
GO:0007517 muscle organ development 1.840538e-3
GO:0048541 Peyer's patch development 1.841180e-3
GO:0071877 regulation of adrenergic receptor signaling pathway 1.874152e-3
GO:0034635 glutathione transport 1.874152e-3
GO:0046952 ketone body catabolic process 1.874152e-3
GO:0045351 type I interferon biosynthetic process 1.890685e-3
GO:0045738 negative regulation of DNA repair 1.902542e-3
GO:0042501 serine phosphorylation of STAT protein 1.902542e-3
GO:0030970 retrograde protein transport, ER to cytosol 1.907052e-3
GO:0070836 caveola assembly 1.907052e-3
GO:0021758 putamen development 1.907052e-3
GO:0021757 caudate nucleus development 1.907052e-3
GO:0006481 C-terminal protein methylation 1.948420e-3
GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly 1.952500e-3
GO:0050773 regulation of dendrite development 1.959943e-3
GO:0030071 regulation of mitotic metaphase/anaphase transition 1.967929e-3
GO:0046653 tetrahydrofolate metabolic process 1.991585e-3
GO:0055021 regulation of cardiac muscle tissue growth 2.044003e-3
GO:0000278 mitotic cell cycle 2.048413e-3
GO:0046777 protein autophosphorylation 2.113851e-3
GO:0021544 subpallium development 2.191227e-3
GO:0001574 ganglioside biosynthetic process 2.194996e-3
GO:0010464 regulation of mesenchymal cell proliferation 2.200317e-3
GO:0021631 optic nerve morphogenesis 2.271213e-3
GO:0007369 gastrulation 2.286362e-3
GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 2.308048e-3
GO:0010987 negative regulation of high-density lipoprotein particle clearance 2.339144e-3
GO:0060434 bronchus morphogenesis 2.339144e-3
GO:0006383 transcription from RNA polymerase III promoter 2.339144e-3
GO:0006269 DNA replication, synthesis of RNA primer 2.339144e-3
GO:0010897 negative regulation of triglyceride catabolic process 2.339144e-3
GO:0006730 one-carbon metabolic process 2.351050e-3
GO:0042304 regulation of fatty acid biosynthetic process 2.363448e-3
GO:0060416 response to growth hormone stimulus 2.382842e-3
GO:0010574 regulation of vascular endothelial growth factor production 2.390922e-3
GO:0035887 aortic smooth muscle cell differentiation 2.393970e-3
GO:0021557 oculomotor nerve development 2.408167e-3
GO:0051965 positive regulation of synapse assembly 2.435907e-3
GO:0021603 cranial nerve formation 2.505486e-3
GO:0055012 ventricular cardiac muscle cell differentiation 2.505769e-3
GO:0048663 neuron fate commitment 2.509847e-3
GO:0001708 cell fate specification 2.566214e-3
GO:0060632 regulation of microtubule-based movement 2.581698e-3
GO:0051954 positive regulation of amine transport 2.605152e-3
GO:0006555 methionine metabolic process 2.618181e-3
GO:0042998 positive regulation of Golgi to plasma membrane protein transport 2.659393e-3
GO:0017196 N-terminal peptidyl-methionine acetylation 2.659393e-3
GO:0033108 mitochondrial respiratory chain complex assembly 2.669284e-3
GO:0048793 pronephros development 2.722069e-3
GO:0060318 definitive erythrocyte differentiation 2.736834e-3
GO:0045333 cellular respiration 2.825572e-3
GO:0019941 modification-dependent protein catabolic process 2.833141e-3
GO:0031427 response to methotrexate 2.837694e-3
GO:2000739 regulation of mesenchymal stem cell differentiation 2.838534e-3
GO:0061326 renal tubule development 2.846056e-3
GO:0043632 modification-dependent macromolecule catabolic process 2.864416e-3
GO:0001832 blastocyst growth 2.892922e-3
GO:0009190 cyclic nucleotide biosynthetic process 2.922767e-3
GO:0010575 positive regulation vascular endothelial growth factor production 2.961429e-3
GO:0030431 sleep 3.046212e-3
GO:0007585 respiratory gaseous exchange 3.064227e-3
GO:0035964 COPI-coated vesicle budding 3.103309e-3
GO:0002645 positive regulation of tolerance induction 3.126211e-3
GO:0001833 inner cell mass cell proliferation 3.185062e-3
GO:0032836 glomerular basement membrane development 3.208236e-3
GO:2000772 regulation of cellular senescence 3.218354e-3
GO:0072080 nephron tubule development 3.237163e-3
GO:0035249 synaptic transmission, glutamatergic 3.247389e-3
GO:0015669 gas transport 3.316069e-3
GO:0043412 macromolecule modification 3.322983e-3
GO:0045768 positive regulation of anti-apoptosis 3.323808e-3
GO:0060192 negative regulation of lipase activity 3.337052e-3
GO:0072234 metanephric nephron tubule development 3.356549e-3
GO:0007095 mitotic cell cycle G2/M transition DNA damage checkpoint 3.371173e-3
GO:0090185 negative regulation of kidney development 3.388742e-3
GO:0070172 positive regulation of tooth mineralization 3.388742e-3
GO:0072184 renal vesicle progenitor cell differentiation 3.501550e-3
GO:0072208 metanephric smooth muscle tissue development 3.501550e-3
GO:0072259 metanephric interstitial cell development 3.501550e-3
GO:0072169 specification of posterior mesonephric tubule identity 3.501550e-3
GO:0090094 metanephric cap mesenchymal cell proliferation involved in metanephros development 3.501550e-3
GO:0072168 specification of anterior mesonephric tubule identity 3.501550e-3
GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development 3.501550e-3
GO:0048313 Golgi inheritance 3.501550e-3
GO:0071879 positive regulation of adrenergic receptor signaling pathway 3.501550e-3
GO:0048265 response to pain 3.526673e-3
GO:0045662 negative regulation of myoblast differentiation 3.575621e-3
GO:0032912 negative regulation of transforming growth factor beta2 production 3.629544e-3
GO:0010310 regulation of hydrogen peroxide metabolic process 3.629544e-3
GO:0046929 negative regulation of neurotransmitter secretion 3.633481e-3
GO:0045083 negative regulation of interleukin-12 biosynthetic process 3.633481e-3
GO:0006357 regulation of transcription from RNA polymerase II promoter 3.717518e-3
GO:0035264 multicellular organism growth 3.758142e-3
GO:0061061 muscle structure development 3.758775e-3
GO:0090381 regulation of heart induction 3.795254e-3
GO:0021750 vestibular nucleus development 3.795254e-3
GO:0010936 negative regulation of macrophage cytokine production 3.795254e-3
GO:0021679 cerebellar molecular layer development 3.795254e-3
GO:0021590 cerebellum maturation 3.795254e-3
GO:0003093 regulation of glomerular filtration 3.799178e-3
GO:0035987 endodermal cell differentiation 3.802466e-3
GO:0021513 spinal cord dorsal/ventral patterning 3.802466e-3
GO:0021510 spinal cord development 3.840690e-3
GO:0042088 T-helper 1 type immune response 3.853835e-3
GO:0071780 mitotic cell cycle G2/M transition checkpoint 3.867917e-3
GO:0060492 lung induction 3.872543e-3
GO:0040023 establishment of nucleus localization 3.896236e-3
GO:0045601 regulation of endothelial cell differentiation 3.959273e-3
GO:0060711 labyrinthine layer development 3.966689e-3
GO:0072170 metanephric tubule development 3.973695e-3
GO:0045799 positive regulation of chromatin assembly or disassembly 3.974828e-3
GO:0044334 canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition 3.974828e-3
GO:0070079 histone H4-R3 demethylation 3.974828e-3
GO:0070078 histone H3-R2 demethylation 3.974828e-3
GO:0060217 hemangioblast cell differentiation 3.974828e-3
GO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process 3.974828e-3
GO:0043148 mitotic spindle stabilization 3.974828e-3
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 3.974828e-3
GO:0042512 negative regulation of tyrosine phosphorylation of Stat1 protein 3.974828e-3
GO:0021935 cerebellar granule cell precursor tangential migration 3.974828e-3
GO:0035881 amacrine cell differentiation 4.066492e-3
GO:0060420 regulation of heart growth 4.094893e-3
GO:0043543 protein acylation 4.100073e-3
GO:0021578 hindbrain maturation 4.105230e-3
GO:0000212 meiotic spindle organization 4.105230e-3
GO:0070995 NADPH oxidation 4.149672e-3
GO:0021819 layer formation in cerebral cortex 4.149672e-3
GO:0048671 negative regulation of collateral sprouting 4.149672e-3
GO:0033554 cellular response to stress 4.153894e-3
GO:0060480 lung goblet cell differentiation 4.182440e-3
GO:0048239 negative regulation of DNA recombination at telomere 4.197607e-3
GO:0045645 positive regulation of eosinophil differentiation 4.197607e-3
GO:0060628 regulation of ER to Golgi vesicle-mediated transport 4.197607e-3
GO:0070535 histone H2A K63-linked ubiquitination 4.197607e-3
GO:0048291 isotype switching to IgG isotypes 4.197607e-3
GO:0021572 rhombomere 6 development 4.197607e-3
GO:0006430 lysyl-tRNA aminoacylation 4.197607e-3
GO:0002368 B cell cytokine production 4.197607e-3
GO:0006741 NADP biosynthetic process 4.197607e-3
GO:0051349 positive regulation of lyase activity 4.213988e-3
GO:0030326 embryonic limb morphogenesis 4.214456e-3
GO:0051647 nucleus localization 4.233371e-3
GO:0008542 visual learning 4.261377e-3
GO:0055114 oxidation-reduction process 4.289862e-3
GO:0060043 regulation of cardiac muscle cell proliferation 4.305089e-3
GO:0048715 negative regulation of oligodendrocyte differentiation 4.335122e-3
GO:0051138 positive regulation of NK T cell differentiation 4.383253e-3
GO:0002066 columnar/cuboidal epithelial cell development 4.383253e-3
GO:0001764 neuron migration 4.434219e-3
GO:0010800 positive regulation of peptidyl-threonine phosphorylation 4.450113e-3
GO:0060045 positive regulation of cardiac muscle cell proliferation 4.557487e-3
GO:0032911 negative regulation of transforming growth factor beta1 production 4.558391e-3
GO:0051967 negative regulation of synaptic transmission, glutamatergic 4.558391e-3
GO:0072197 ureter morphogenesis 4.558391e-3
GO:0043353 enucleate erythrocyte differentiation 4.558391e-3
GO:0051322 anaphase 4.579770e-3
GO:0045722 positive regulation of gluconeogenesis 4.579770e-3
GO:0042542 response to hydrogen peroxide 4.640578e-3
GO:2000015 regulation of determination of dorsal identity 4.641839e-3
GO:0010724 regulation of definitive erythrocyte differentiation 4.641839e-3
GO:0051238 sequestering of metal ion 4.641839e-3
GO:0051899 membrane depolarization 4.688090e-3
GO:0033091 positive regulation of immature T cell proliferation 4.714009e-3
GO:0051028 mRNA transport 4.727814e-3
GO:0040034 regulation of development, heterochronic 4.783293e-3
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 4.814643e-3
GO:0019222 regulation of metabolic process 4.821968e-3
GO:0000302 response to reactive oxygen species 4.854959e-3
GO:0033083 regulation of immature T cell proliferation 4.856274e-3
GO:0051154 negative regulation of striated muscle cell differentiation 4.909682e-3
GO:0072148 epithelial cell fate commitment 4.909682e-3
GO:0007052 mitotic spindle organization 4.909682e-3
GO:0009060 aerobic respiration 4.965126e-3
GO:0007519 skeletal muscle tissue development 5.007841e-3
GO:0006511 ubiquitin-dependent protein catabolic process 5.080486e-3
GO:0048537 mucosal-associated lymphoid tissue development 5.131764e-3
GO:0007379 segment specification 5.131764e-3
GO:0060083 smooth muscle contraction involved in micturition 5.190190e-3
GO:0051016 barbed-end actin filament capping 5.213340e-3
GO:0007216 metabotropic glutamate receptor signaling pathway 5.246491e-3
GO:0055117 regulation of cardiac muscle contraction 5.269736e-3
GO:0002639 positive regulation of immunoglobulin production 5.301183e-3
GO:0055069 zinc ion homeostasis 5.340216e-3
GO:0046686 response to cadmium ion 5.343569e-3
GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development 5.373592e-3
GO:0060215 primitive hemopoiesis 5.373592e-3
GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 5.384151e-3
GO:0050803 regulation of synapse structure and activity 5.433836e-3
GO:0051726 regulation of cell cycle 5.462034e-3
GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis 5.467604e-3
GO:0042744 hydrogen peroxide catabolic process 5.574959e-3
GO:0043647 inositol phosphate metabolic process 5.604460e-3
GO:0050748 negative regulation of lipoprotein metabolic process 5.604627e-3
GO:0032981 mitochondrial respiratory chain complex I assembly 5.604627e-3
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 5.609394e-3
GO:0006599 phosphagen metabolic process 5.610377e-3
GO:0008631 induction of apoptosis by oxidative stress 5.642484e-3
GO:0060484 lung-associated mesenchyme development 5.754187e-3
GO:0021542 dentate gyrus development 5.770853e-3
GO:0009247 glycolipid biosynthetic process 5.770853e-3
GO:0060998 regulation of dendritic spine development 5.805931e-3
GO:2000124 regulation of endocannabinoid signaling pathway 5.837073e-3
GO:0006312 mitotic recombination 5.837073e-3
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 5.911959e-3
GO:0042268 regulation of cytolysis 5.926822e-3
GO:0060977 coronary vasculature morphogenesis 5.945109e-3
GO:0051924 regulation of calcium ion transport 5.947969e-3
GO:0031572 G2/M transition DNA damage checkpoint 6.010748e-3
GO:0071299 cellular response to vitamin A 6.019868e-3
GO:0045908 negative regulation of vasodilation 6.086689e-3
GO:0072172 mesonephric tubule formation 6.132064e-3
GO:0001892 embryonic placenta development 6.199841e-3
GO:0051597 response to methylmercury 6.224972e-3
GO:0034101 erythrocyte homeostasis 6.274163e-3
GO:0033344 cholesterol efflux 6.339038e-3
GO:0071300 cellular response to retinoic acid 6.341522e-3
GO:0048285 organelle fission 6.427136e-3
GO:0046341 CDP-diacylglycerol metabolic process 6.441527e-3
GO:0045759 negative regulation of action potential 6.441527e-3
GO:0006438 valyl-tRNA aminoacylation 6.441527e-3
GO:0072207 metanephric epithelium development 6.449082e-3
GO:0035307 positive regulation of protein dephosphorylation 6.511522e-3
GO:0033152 immunoglobulin V(D)J recombination 6.511522e-3
GO:0018130 heterocycle biosynthetic process 6.579571e-3
GO:0046425 regulation of JAK-STAT cascade 6.639011e-3
GO:2000685 positive regulation of cellular response to X-ray 6.690858e-3
GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining 6.690858e-3
GO:0035988 chondrocyte proliferation 6.690858e-3
GO:2001038 regulation of cellular response to drug 6.690858e-3
GO:0031052 chromosome breakage 6.690858e-3
GO:0035978 histone H2A-S139 phosphorylation 6.690858e-3
GO:0003131 mesodermal-endodermal cell signaling 6.690858e-3
GO:0035166 post-embryonic hemopoiesis 6.690858e-3
GO:0046148 pigment biosynthetic process 6.702069e-3
GO:0021535 cell migration in hindbrain 6.713113e-3