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Novel motif:88

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name:motif88_CCCTCTTT

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0031326 regulation of cellular biosynthetic process 4.297795e-18
GO:0009889 regulation of biosynthetic process 4.523206e-16
GO:0010829 negative regulation of glucose transport 1.086096e-15
GO:2000112 regulation of cellular macromolecule biosynthetic process 2.588318e-15
GO:0031327 negative regulation of cellular biosynthetic process 3.823163e-15
GO:2000113 negative regulation of cellular macromolecule biosynthetic process 4.395990e-15
GO:0051252 regulation of RNA metabolic process 5.504466e-15
GO:0006355 regulation of transcription, DNA-dependent 1.191126e-14
GO:0009890 negative regulation of biosynthetic process 1.200848e-14
GO:0010558 negative regulation of macromolecule biosynthetic process 1.950783e-14
GO:0006357 regulation of transcription from RNA polymerase II promoter 4.499945e-14
GO:0010629 negative regulation of gene expression 5.229606e-14
GO:0048705 skeletal system morphogenesis 2.230831e-13
GO:0010556 regulation of macromolecule biosynthetic process 2.258155e-13
GO:0001957 intramembranous ossification 2.562907e-13
GO:0045892 negative regulation of transcription, DNA-dependent 4.655954e-13
GO:0010468 regulation of gene expression 7.601940e-13
GO:0051253 negative regulation of RNA metabolic process 1.014506e-12
GO:0051172 negative regulation of nitrogen compound metabolic process 1.535213e-12
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 2.065757e-12
GO:0002706 regulation of lymphocyte mediated immunity 2.123304e-12
GO:0019219 regulation of nucleobase-containing compound metabolic process 3.402315e-12
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 4.943038e-12
GO:0045893 positive regulation of transcription, DNA-dependent 5.627191e-12
GO:0051254 positive regulation of RNA metabolic process 5.990447e-12
GO:0051173 positive regulation of nitrogen compound metabolic process 7.008020e-12
GO:0060346 bone trabecula formation 7.806626e-12
GO:0045415 negative regulation of interleukin-8 biosynthetic process 7.889734e-12
GO:0051171 regulation of nitrogen compound metabolic process 1.047650e-11
GO:0035418 protein localization to synapse 1.114705e-11
GO:0060351 cartilage development involved in endochondral bone morphogenesis 1.125166e-11
GO:0045944 positive regulation of transcription from RNA polymerase II promoter 1.168216e-11
GO:0009892 negative regulation of metabolic process 1.448708e-11
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 2.366141e-11
GO:0010605 negative regulation of macromolecule metabolic process 2.993670e-11
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 3.002921e-11
GO:0043270 positive regulation of ion transport 4.221010e-11
GO:0051239 regulation of multicellular organismal process 4.695437e-11
GO:0050890 cognition 5.770332e-11
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6.198557e-11
GO:0010628 positive regulation of gene expression 8.531465e-11
GO:0031328 positive regulation of cellular biosynthetic process 8.764965e-11
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 9.547485e-11
GO:0002712 regulation of B cell mediated immunity 1.126347e-10
GO:0060349 bone morphogenesis 1.667700e-10
GO:0031324 negative regulation of cellular metabolic process 2.088565e-10
GO:0014070 response to organic cyclic compound 3.030931e-10
GO:0060350 endochondral bone morphogenesis 3.649707e-10
GO:0007611 learning or memory 3.821061e-10
GO:0010718 positive regulation of epithelial to mesenchymal transition 4.856459e-10
GO:0001941 postsynaptic membrane organization 4.899648e-10
GO:0002819 regulation of adaptive immune response 5.672214e-10
GO:0050877 neurological system process 6.001631e-10
GO:0002889 regulation of immunoglobulin mediated immune response 7.603911e-10
GO:0001958 endochondral ossification 8.204570e-10
GO:0002315 marginal zone B cell differentiation 8.344287e-10
GO:0045064 T-helper 2 cell differentiation 8.344287e-10
GO:0006351 transcription, DNA-dependent 1.828126e-9
GO:0014050 negative regulation of glutamate secretion 2.257911e-9
GO:0060712 spongiotrophoblast layer development 2.490770e-9
GO:0031668 cellular response to extracellular stimulus 3.615533e-9
GO:0048523 negative regulation of cellular process 3.811179e-9
GO:0002268 follicular dendritic cell differentiation 5.740217e-9
GO:0070164 negative regulation of adiponectin secretion 5.909681e-9
GO:0060355 positive regulation of cell adhesion molecule production 5.909681e-9
GO:0035505 positive regulation of myosin light chain kinase activity 5.909681e-9
GO:0002708 positive regulation of lymphocyte mediated immunity 6.179900e-9
GO:0048598 embryonic morphogenesis 6.309133e-9
GO:0010717 regulation of epithelial to mesenchymal transition 6.324160e-9
GO:0003002 regionalization 6.480348e-9
GO:0048519 negative regulation of biological process 6.488843e-9
GO:0050804 regulation of synaptic transmission 6.599159e-9
GO:0043009 chordate embryonic development 6.843806e-9
GO:0034505 tooth mineralization 6.988181e-9
GO:0071496 cellular response to external stimulus 7.018088e-9
GO:2000467 positive regulation of glycogen (starch) synthase activity 7.215087e-9
GO:0022603 regulation of anatomical structure morphogenesis 7.526019e-9
GO:0009991 response to extracellular stimulus 7.849397e-9
GO:0016140 O-glycoside metabolic process 8.548314e-9
GO:0031622 positive regulation of fever generation 8.768704e-9
GO:0031323 regulation of cellular metabolic process 1.039483e-8
GO:0010557 positive regulation of macromolecule biosynthetic process 1.210885e-8
GO:0007612 learning 1.271466e-8
GO:0070208 protein heterotrimerization 1.322802e-8
GO:0009891 positive regulation of biosynthetic process 1.476338e-8
GO:0031652 positive regulation of heat generation 1.576942e-8
GO:0070163 regulation of adiponectin secretion 1.596548e-8
GO:0060348 bone development 1.607541e-8
GO:0080090 regulation of primary metabolic process 1.615488e-8
GO:0021871 forebrain regionalization 1.748522e-8
GO:0070587 regulation of cell-cell adhesion involved in gastrulation 1.840426e-8
GO:0034114 regulation of heterotypic cell-cell adhesion 1.840426e-8
GO:0042634 regulation of hair cycle 1.990114e-8
GO:0002439 chronic inflammatory response to antigenic stimulus 2.162727e-8
GO:0044057 regulation of system process 2.280669e-8
GO:0031325 positive regulation of cellular metabolic process 2.405480e-8
GO:0046325 negative regulation of glucose import 2.550346e-8
GO:0051797 regulation of hair follicle development 2.729818e-8
GO:0044060 regulation of endocrine process 2.950664e-8
GO:0097120 receptor localization to synapse 3.215015e-8
GO:0072578 neurotransmitter-gated ion channel clustering 3.215015e-8
GO:2000465 regulation of glycogen (starch) synthase activity 3.285888e-8
GO:0010765 positive regulation of sodium ion transport 3.363883e-8
GO:0045838 positive regulation of membrane potential 3.557007e-8
GO:0010470 regulation of gastrulation 3.956546e-8
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 4.517462e-8
GO:0009792 embryo development ending in birth or egg hatching 5.660351e-8
GO:0045840 positive regulation of mitosis 5.679944e-8
GO:0051781 positive regulation of cell division 5.764773e-8
GO:0032774 RNA biosynthetic process 6.317369e-8
GO:0051094 positive regulation of developmental process 6.581632e-8
GO:0060323 head morphogenesis 6.860003e-8
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6.971480e-8
GO:0032355 response to estradiol stimulus 7.186834e-8
GO:0097113 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering 7.398626e-8
GO:0060325 face morphogenesis 7.582774e-8
GO:2000463 positive regulation of excitatory postsynaptic membrane potential 8.159368e-8
GO:0007565 female pregnancy 8.770849e-8
GO:0060429 epithelium development 9.418884e-8
GO:0071637 regulation of monocyte chemotactic protein-1 production 1.086730e-7
GO:0009612 response to mechanical stimulus 1.146532e-7
GO:0010893 positive regulation of steroid biosynthetic process 1.153835e-7
GO:2000026 regulation of multicellular organismal development 1.192167e-7
GO:0007267 cell-cell signaling 1.201358e-7
GO:0060216 definitive hemopoiesis 1.273687e-7
GO:0002703 regulation of leukocyte mediated immunity 1.326891e-7
GO:0009790 embryo development 1.395404e-7
GO:0051798 positive regulation of hair follicle development 1.499058e-7
GO:0046827 positive regulation of protein export from nucleus 1.681168e-7
GO:0001503 ossification 1.726751e-7
GO:0045410 positive regulation of interleukin-6 biosynthetic process 1.793768e-7
GO:0002821 positive regulation of adaptive immune response 2.090041e-7
GO:0034116 positive regulation of heterotypic cell-cell adhesion 2.204775e-7
GO:0007613 memory 2.305952e-7
GO:0030730 sequestering of triglyceride 2.443911e-7
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity 2.481727e-7
GO:0061138 morphogenesis of a branching epithelium 2.482063e-7
GO:0046626 regulation of insulin receptor signaling pathway 2.564970e-7
GO:0048545 response to steroid hormone stimulus 3.061725e-7
GO:0060706 cell differentiation involved in embryonic placenta development 3.062389e-7
GO:0043627 response to estrogen stimulus 3.312020e-7
GO:0017145 stem cell division 3.791157e-7
GO:0046068 cGMP metabolic process 4.281735e-7
GO:0031644 regulation of neurological system process 4.361513e-7
GO:0035690 cellular response to drug 4.467926e-7
GO:0048706 embryonic skeletal system development 4.649380e-7
GO:0045765 regulation of angiogenesis 4.880604e-7
GO:0048522 positive regulation of cellular process 5.254066e-7
GO:0051302 regulation of cell division 5.421500e-7
GO:0009952 anterior/posterior pattern specification 5.454278e-7
GO:0030799 regulation of cyclic nucleotide metabolic process 5.835644e-7
GO:0010171 body morphogenesis 5.858566e-7
GO:0001660 fever generation 6.052197e-7
GO:0045766 positive regulation of angiogenesis 6.346908e-7
GO:0033129 positive regulation of histone phosphorylation 6.606078e-7
GO:0045994 positive regulation of translational initiation by iron 7.061621e-7
GO:0002037 negative regulation of L-glutamate transport 7.061621e-7
GO:0045778 positive regulation of ossification 7.297053e-7
GO:0043266 regulation of potassium ion transport 8.398682e-7
GO:0065007 biological regulation 8.518841e-7
GO:0001892 embryonic placenta development 8.567704e-7
GO:0033209 tumor necrosis factor-mediated signaling pathway 8.706767e-7
GO:0032308 positive regulation of prostaglandin secretion 9.205602e-7
GO:0050794 regulation of cellular process 9.434372e-7
GO:0036006 cellular response to macrophage colony-stimulating factor stimulus 9.621489e-7
GO:0035105 sterol regulatory element binding protein import into nucleus 9.700081e-7
GO:0002467 germinal center formation 1.085047e-6
GO:0071639 positive regulation of monocyte chemotactic protein-1 production 1.119183e-6
GO:0052697 xenobiotic glucuronidation 1.139396e-6
GO:0070980 biphenyl catabolic process 1.139396e-6
GO:0052696 flavonoid glucuronidation 1.139396e-6
GO:0016142 O-glycoside catabolic process 1.139396e-6
GO:0051552 flavone metabolic process 1.139396e-6
GO:0006789 bilirubin conjugation 1.139396e-6
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 1.182285e-6
GO:0001823 mesonephros development 1.209018e-6
GO:0002920 regulation of humoral immune response 1.211836e-6
GO:0042093 T-helper cell differentiation 1.246594e-6
GO:0071230 cellular response to amino acid stimulus 1.257867e-6
GO:0051899 membrane depolarization 1.306099e-6
GO:0051216 cartilage development 1.316895e-6
GO:0051148 negative regulation of muscle cell differentiation 1.364951e-6
GO:0010604 positive regulation of macromolecule metabolic process 1.404109e-6
GO:0033280 response to vitamin D 1.408044e-6
GO:0007389 pattern specification process 1.421201e-6
GO:0033273 response to vitamin 1.442281e-6
GO:0032753 positive regulation of interleukin-4 production 1.444255e-6
GO:0045906 negative regulation of vasoconstriction 1.460520e-6
GO:0070904 transepithelial L-ascorbic acid transport 1.487358e-6
GO:0032874 positive regulation of stress-activated MAPK cascade 1.496613e-6
GO:0010469 regulation of receptor activity 1.518036e-6
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 1.525900e-6
GO:0001890 placenta development 1.578010e-6
GO:0060670 branching involved in embryonic placenta morphogenesis 1.586518e-6
GO:0051930 regulation of sensory perception of pain 1.623838e-6
GO:0060255 regulation of macromolecule metabolic process 1.633115e-6
GO:0032892 positive regulation of organic acid transport 1.649284e-6
GO:0046543 development of secondary female sexual characteristics 1.651701e-6
GO:0050806 positive regulation of synaptic transmission 2.044107e-6
GO:0022601 menstrual cycle phase 2.048007e-6
GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 2.270252e-6
GO:0051043 regulation of membrane protein ectodomain proteolysis 2.464496e-6
GO:0050789 regulation of biological process 2.512321e-6
GO:0010467 gene expression 2.558151e-6
GO:0051901 positive regulation of mitochondrial depolarization 2.589721e-6
GO:0045787 positive regulation of cell cycle 2.658994e-6
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 3.003418e-6
GO:0014805 smooth muscle adaptation 3.081126e-6
GO:0090287 regulation of cellular response to growth factor stimulus 3.222803e-6
GO:0051044 positive regulation of membrane protein ectodomain proteolysis 3.334008e-6
GO:0032964 collagen biosynthetic process 3.368235e-6
GO:0002437 inflammatory response to antigenic stimulus 3.465643e-6
GO:0031667 response to nutrient levels 3.519024e-6
GO:0030802 regulation of cyclic nucleotide biosynthetic process 3.622748e-6
GO:0010720 positive regulation of cell development 3.682169e-6
GO:0097119 postsynaptic density protein 95 clustering 4.099655e-6
GO:0097104 postsynaptic membrane assembly 4.099655e-6
GO:0032649 regulation of interferon-gamma production 4.197389e-6
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 4.341889e-6
GO:0031444 slow-twitch skeletal muscle fiber contraction 4.404410e-6
GO:0043588 skin development 4.457036e-6
GO:0031058 positive regulation of histone modification 4.463912e-6
GO:0051241 negative regulation of multicellular organismal process 4.469581e-6
GO:0060343 trabecula formation 4.513597e-6
GO:0051971 positive regulation of transmission of nerve impulse 4.642598e-6
GO:0097116 gephyrin clustering 4.739653e-6
GO:0048536 spleen development 4.788978e-6
GO:0046888 negative regulation of hormone secretion 4.795543e-6
GO:0072176 nephric duct development 4.883680e-6
GO:0051291 protein heterooligomerization 4.901200e-6
GO:0035272 exocrine system development 4.929512e-6
GO:0030326 embryonic limb morphogenesis 4.990587e-6
GO:0051591 response to cAMP 5.044327e-6
GO:0045684 positive regulation of epidermis development 5.196505e-6
GO:0021798 forebrain dorsal/ventral pattern formation 5.386458e-6
GO:0009893 positive regulation of metabolic process 5.802875e-6
GO:0003097 renal water transport 5.830558e-6
GO:0032729 positive regulation of interferon-gamma production 5.909701e-6
GO:0007184 SMAD protein import into nucleus 5.911777e-6
GO:0048730 epidermis morphogenesis 5.998364e-6
GO:0090303 positive regulation of wound healing 6.201360e-6
GO:0008306 associative learning 6.383842e-6
GO:0051956 negative regulation of amino acid transport 6.575778e-6
GO:0048167 regulation of synaptic plasticity 6.725161e-6
GO:0045086 positive regulation of interleukin-2 biosynthetic process 6.985430e-6
GO:0001501 skeletal system development 7.152373e-6
GO:0014819 regulation of skeletal muscle contraction 7.390573e-6
GO:0001825 blastocyst formation 7.418183e-6
GO:0035066 positive regulation of histone acetylation 7.772955e-6
GO:0031056 regulation of histone modification 8.101520e-6
GO:0042127 regulation of cell proliferation 8.385371e-6
GO:0007399 nervous system development 8.523580e-6
GO:0051130 positive regulation of cellular component organization 8.586004e-6
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 9.045829e-6
GO:0060997 dendritic spine morphogenesis 9.128894e-6
GO:0045682 regulation of epidermis development 9.521266e-6
GO:0010994 free ubiquitin chain polymerization 9.786350e-6
GO:0030213 hyaluronan biosynthetic process 9.859541e-6
GO:0070482 response to oxygen levels 9.934478e-6
GO:0048568 embryonic organ development 9.944124e-6
GO:0008544 epidermis development 1.026839e-5
GO:0032846 positive regulation of homeostatic process 1.068810e-5
GO:0045599 negative regulation of fat cell differentiation 1.077014e-5
GO:2000193 positive regulation of fatty acid transport 1.082483e-5
GO:0030814 regulation of cAMP metabolic process 1.092648e-5
GO:0010769 regulation of cell morphogenesis involved in differentiation 1.157072e-5
GO:0061383 trabecula morphogenesis 1.209357e-5
GO:0033127 regulation of histone phosphorylation 1.225554e-5
GO:0010193 response to ozone 1.255229e-5
GO:0071310 cellular response to organic substance 1.414102e-5
GO:0048771 tissue remodeling 1.473936e-5
GO:0032720 negative regulation of tumor necrosis factor production 1.547754e-5
GO:0019222 regulation of metabolic process 1.559089e-5
GO:0016242 negative regulation of macroautophagy 1.611017e-5
GO:0031111 negative regulation of microtubule polymerization or depolymerization 1.666574e-5
GO:0060708 spongiotrophoblast differentiation 1.709448e-5
GO:0031646 positive regulation of neurological system process 1.745314e-5
GO:0045662 negative regulation of myoblast differentiation 1.755232e-5
GO:0090031 positive regulation of steroid hormone biosynthetic process 1.755232e-5
GO:0042026 protein refolding 1.772753e-5
GO:0046889 positive regulation of lipid biosynthetic process 1.813604e-5
GO:0045074 regulation of interleukin-10 biosynthetic process 1.857998e-5
GO:0030817 regulation of cAMP biosynthetic process 1.894729e-5
GO:0050891 multicellular organismal water homeostasis 1.945828e-5
GO:0071417 cellular response to organic nitrogen 1.976731e-5
GO:0071300 cellular response to retinoic acid 1.984755e-5
GO:0006447 regulation of translational initiation by iron 2.028302e-5
GO:0055012 ventricular cardiac muscle cell differentiation 2.057459e-5
GO:0051454 intracellular pH elevation 2.086173e-5
GO:0071229 cellular response to acid 2.098096e-5
GO:0051928 positive regulation of calcium ion transport 2.185742e-5
GO:0060976 coronary vasculature development 2.204667e-5
GO:0003008 system process 2.233935e-5
GO:0003091 renal water homeostasis 2.340047e-5
GO:0002699 positive regulation of immune effector process 2.378168e-5
GO:0002921 negative regulation of humoral immune response 2.421738e-5
GO:0035721 intraflagellar retrograde transport 2.467387e-5
GO:0031960 response to corticosteroid stimulus 2.486854e-5
GO:0032933 SREBP-mediated signaling pathway 2.495937e-5
GO:0043279 response to alkaloid 2.546118e-5
GO:0010535 positive regulation of activation of JAK2 kinase activity 2.553098e-5
GO:0031279 regulation of cyclase activity 2.553557e-5
GO:0007435 salivary gland morphogenesis 2.569977e-5
GO:0001974 blood vessel remodeling 2.580290e-5
GO:0070309 lens fiber cell morphogenesis 2.582844e-5
GO:0043589 skin morphogenesis 2.611651e-5
GO:0071418 cellular response to amine stimulus 2.646576e-5
GO:0060486 Clara cell differentiation 2.680779e-5
GO:0045761 regulation of adenylate cyclase activity 2.703940e-5
GO:0060430 lung saccule development 2.850629e-5
GO:0060364 frontal suture morphogenesis 2.956311e-5
GO:0042696 menarche 2.963191e-5
GO:0042755 eating behavior 2.975361e-5
GO:0071495 cellular response to endogenous stimulus 3.058193e-5
GO:0021554 optic nerve development 3.175481e-5
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 3.269759e-5
GO:0032526 response to retinoic acid 3.415185e-5
GO:0016241 regulation of macroautophagy 3.437045e-5
GO:0030952 establishment or maintenance of cytoskeleton polarity 3.477307e-5
GO:0031669 cellular response to nutrient levels 3.504856e-5
GO:0010936 negative regulation of macrophage cytokine production 3.662031e-5
GO:0045136 development of secondary sexual characteristics 3.666328e-5
GO:0009653 anatomical structure morphogenesis 3.739990e-5
GO:0002293 alpha-beta T cell differentiation involved in immune response 3.890171e-5
GO:0072178 nephric duct morphogenesis 3.892595e-5
GO:0001763 morphogenesis of a branching structure 3.921866e-5
GO:0045556 positive regulation of TRAIL biosynthetic process 3.926299e-5
GO:0007610 behavior 3.943220e-5
GO:0010646 regulation of cell communication 3.961626e-5
GO:0017148 negative regulation of translation 4.032286e-5
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 4.095391e-5
GO:0045940 positive regulation of steroid metabolic process 4.253993e-5
GO:0060124 positive regulation of growth hormone secretion 4.261737e-5
GO:0002009 morphogenesis of an epithelium 4.299016e-5
GO:0051240 positive regulation of multicellular organismal process 4.376001e-5
GO:0048562 embryonic organ morphogenesis 4.376816e-5
GO:0042073 intraflagellar transport 4.507726e-5
GO:0051968 positive regulation of synaptic transmission, glutamatergic 4.607986e-5
GO:0007268 synaptic transmission 4.624044e-5
GO:0072321 chaperone-mediated protein transport 4.676290e-5
GO:0001649 osteoblast differentiation 4.702855e-5
GO:0015809 arginine transport 4.802020e-5
GO:0097118 neuroligin clustering 4.965091e-5
GO:0000302 response to reactive oxygen species 5.014988e-5
GO:0051969 regulation of transmission of nerve impulse 5.061228e-5
GO:0060035 notochord cell development 5.076249e-5
GO:0043278 response to morphine 5.164956e-5
GO:0030111 regulation of Wnt receptor signaling pathway 5.347023e-5
GO:0045657 positive regulation of monocyte differentiation 5.369146e-5
GO:0016070 RNA metabolic process 5.376345e-5
GO:0043491 protein kinase B signaling cascade 5.492337e-5
GO:0032663 regulation of interleukin-2 production 5.565715e-5
GO:0006701 progesterone biosynthetic process 5.765804e-5
GO:0042476 odontogenesis 5.837585e-5
GO:0021797 forebrain anterior/posterior pattern specification 6.007003e-5
GO:0019226 transmission of nerve impulse 6.036958e-5
GO:0042108 positive regulation of cytokine biosynthetic process 6.162180e-5
GO:0001661 conditioned taste aversion 6.174409e-5
GO:0035176 social behavior 6.242882e-5
GO:0015804 neutral amino acid transport 6.462663e-5
GO:0050886 endocrine process 6.513868e-5
GO:0072177 mesonephric duct development 6.518175e-5
GO:0048168 regulation of neuronal synaptic plasticity 6.542432e-5
GO:0019086 late viral mRNA transcription 6.544263e-5
GO:0007605 sensory perception of sound 6.851433e-5
GO:0019730 antimicrobial humoral response 6.858459e-5
GO:0003218 cardiac left ventricle formation 6.881663e-5
GO:0001829 trophectodermal cell differentiation 6.980055e-5
GO:0046628 positive regulation of insulin receptor signaling pathway 7.073839e-5
GO:0060707 trophoblast giant cell differentiation 7.240865e-5
GO:0045076 regulation of interleukin-2 biosynthetic process 7.293893e-5
GO:0045948 positive regulation of translational initiation 7.533171e-5
GO:0051339 regulation of lyase activity 7.744616e-5
GO:0060284 regulation of cell development 7.775006e-5
GO:2000273 positive regulation of receptor activity 7.902828e-5
GO:0048639 positive regulation of developmental growth 8.173261e-5
GO:0007566 embryo implantation 8.687327e-5
GO:0007431 salivary gland development 8.762281e-5
GO:0035507 regulation of myosin-light-chain-phosphatase activity 8.861956e-5
GO:0048133 male germ-line stem cell division 8.965192e-5
GO:0003417 growth plate cartilage development 8.987487e-5
GO:0071299 cellular response to vitamin A 9.230950e-5
GO:0030199 collagen fibril organization 9.392629e-5
GO:0002711 positive regulation of T cell mediated immunity 9.401510e-5
GO:0030501 positive regulation of bone mineralization 9.440261e-5
GO:0002697 regulation of immune effector process 9.686138e-5
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 9.971137e-5
GO:0002089 lens morphogenesis in camera-type eye 1.006332e-4
GO:0051896 regulation of protein kinase B signaling cascade 1.007014e-4
GO:0002544 chronic inflammatory response 1.019116e-4
GO:0001666 response to hypoxia 1.082818e-4
GO:0010715 regulation of extracellular matrix disassembly 1.174306e-4
GO:0051897 positive regulation of protein kinase B signaling cascade 1.184143e-4
GO:0070169 positive regulation of biomineral tissue development 1.227668e-4
GO:0071985 multivesicular body sorting pathway 1.273280e-4
GO:0003009 skeletal muscle contraction 1.303401e-4
GO:0072215 regulation of metanephros development 1.305306e-4
GO:0060828 regulation of canonical Wnt receptor signaling pathway 1.309882e-4
GO:0010159 specification of organ position 1.336352e-4
GO:0042593 glucose homeostasis 1.421058e-4
GO:0035752 lysosomal lumen pH elevation 1.422774e-4
GO:0000046 autophagic vacuole fusion 1.422774e-4
GO:0001575 globoside metabolic process 1.422774e-4
GO:0033591 response to L-ascorbic acid 1.477410e-4
GO:0007369 gastrulation 1.485113e-4
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway 1.486757e-4
GO:0032890 regulation of organic acid transport 1.547921e-4
GO:0035065 regulation of histone acetylation 1.549180e-4
GO:0034405 response to fluid shear stress 1.571830e-4
GO:0032872 regulation of stress-activated MAPK cascade 1.589240e-4
GO:0045637 regulation of myeloid cell differentiation 1.635610e-4
GO:0006620 posttranslational protein targeting to membrane 1.650156e-4
GO:0042946 glucoside transport 1.651830e-4
GO:0061302 smooth muscle cell-matrix adhesion 1.656942e-4
GO:0060669 embryonic placenta morphogenesis 1.662393e-4
GO:0043268 positive regulation of potassium ion transport 1.667166e-4
GO:0010225 response to UV-C 1.714895e-4
GO:0030327 prenylated protein catabolic process 1.742864e-4
GO:0009887 organ morphogenesis 1.760775e-4
GO:0045123 cellular extravasation 1.765253e-4
GO:0042035 regulation of cytokine biosynthetic process 1.843463e-4
GO:0016055 Wnt receptor signaling pathway 1.850339e-4
GO:0043932 ossification involved in bone remodeling 1.853737e-4
GO:0050881 musculoskeletal movement 1.855467e-4
GO:0016188 synaptic vesicle maturation 1.875879e-4
GO:0060444 branching involved in mammary gland duct morphogenesis 1.900877e-4
GO:2000109 regulation of macrophage apoptosis 1.904926e-4
GO:0090361 regulation of platelet-derived growth factor production 1.968478e-4
GO:0042104 positive regulation of activated T cell proliferation 2.044772e-4
GO:0002036 regulation of L-glutamate transport 2.045494e-4
GO:0001909 leukocyte mediated cytotoxicity 2.092067e-4
GO:0060322 head development 2.111672e-4
GO:0007601 visual perception 2.136844e-4
GO:0009953 dorsal/ventral pattern formation 2.182038e-4
GO:0035136 forelimb morphogenesis 2.236672e-4
GO:0010912 positive regulation of isomerase activity 2.308969e-4
GO:0010243 response to organic nitrogen 2.443700e-4
GO:0061005 cell differentiation involved in kidney development 2.504871e-4
GO:0072179 nephric duct formation 2.512925e-4
GO:0023041 neuronal signal transduction 2.513048e-4
GO:0048518 positive regulation of biological process 2.643719e-4
GO:0070633 transepithelial transport 2.684341e-4
GO:0046511 sphinganine biosynthetic process 2.733804e-4
GO:0072160 nephron tubule epithelial cell differentiation 2.744619e-4
GO:0002891 positive regulation of immunoglobulin mediated immune response 2.783323e-4
GO:0060996 dendritic spine development 2.802981e-4
GO:0010716 negative regulation of extracellular matrix disassembly 2.805011e-4
GO:0060021 palate development 2.850227e-4
GO:0008284 positive regulation of cell proliferation 2.883379e-4
GO:0050953 sensory perception of light stimulus 2.920317e-4
GO:0002028 regulation of sodium ion transport 3.095726e-4
GO:0019985 translesion synthesis 3.114329e-4
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 3.145082e-4
GO:2000110 negative regulation of macrophage apoptosis 3.186896e-4
GO:2000363 positive regulation of prostaglandin-E synthase activity 3.186896e-4
GO:0071608 macrophage inflammatory protein-1 alpha production 3.186896e-4
GO:0032701 negative regulation of interleukin-18 production 3.186896e-4
GO:0032498 detection of muramyl dipeptide 3.186896e-4
GO:0006965 positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria 3.186896e-4
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity 3.227033e-4
GO:0044027 hypermethylation of CpG island 3.233968e-4
GO:0043923 positive regulation by host of viral transcription 3.236132e-4
GO:0060235 lens induction in camera-type eye 3.236132e-4
GO:0006446 regulation of translational initiation 3.255418e-4
GO:0042267 natural killer cell mediated cytotoxicity 3.261988e-4
GO:0030431 sleep 3.276962e-4
GO:0060078 regulation of postsynaptic membrane potential 3.289693e-4
GO:0061037 negative regulation of cartilage development 3.290007e-4
GO:0006621 protein retention in ER lumen 3.312628e-4
GO:0030856 regulation of epithelial cell differentiation 3.313286e-4
GO:0043586 tongue development 3.337989e-4
GO:0046069 cGMP catabolic process 3.348184e-4
GO:2000725 regulation of cardiac muscle cell differentiation 3.478053e-4
GO:0032736 positive regulation of interleukin-13 production 3.478053e-4
GO:0001817 regulation of cytokine production 3.508088e-4
GO:0007600 sensory perception 3.555066e-4
GO:0051955 regulation of amino acid transport 3.582913e-4
GO:0009804 coumarin metabolic process 3.586040e-4
GO:0060206 estrous cycle phase 3.644801e-4
GO:0001505 regulation of neurotransmitter levels 3.659414e-4
GO:0007423 sensory organ development 3.661071e-4
GO:0045911 positive regulation of DNA recombination 3.667368e-4
GO:0045061 thymic T cell selection 3.696579e-4
GO:0045414 regulation of interleukin-8 biosynthetic process 3.703850e-4
GO:0007442 hindgut morphogenesis 3.713541e-4
GO:0001704 formation of primary germ layer 3.741179e-4
GO:0048332 mesoderm morphogenesis 3.741697e-4
GO:0042256 mature ribosome assembly 3.784028e-4
GO:0035441 cell migration involved in vasculogenesis 3.784028e-4
GO:0035850 epithelial cell differentiation involved in kidney development 3.794606e-4
GO:0045408 regulation of interleukin-6 biosynthetic process 3.811016e-4
GO:0030855 epithelial cell differentiation 3.826410e-4
GO:0031343 positive regulation of cell killing 3.861504e-4
GO:0043113 receptor clustering 3.912708e-4
GO:0048704 embryonic skeletal system morphogenesis 3.924585e-4
GO:0070848 response to growth factor stimulus 3.978936e-4
GO:0006527 arginine catabolic process 4.059163e-4
GO:0021631 optic nerve morphogenesis 4.141911e-4
GO:0045191 regulation of isotype switching 4.144406e-4
GO:0008285 negative regulation of cell proliferation 4.200332e-4


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0006357 regulation of transcription from RNA polymerase II promoter 8.261708e-16
GO:0060350 endochondral bone morphogenesis 3.967179e-13
GO:0060349 bone morphogenesis 4.842435e-13
GO:0010556 regulation of macromolecule biosynthetic process 1.365472e-12
GO:0016579 protein deubiquitination 2.624979e-12
GO:0060351 cartilage development involved in endochondral bone morphogenesis 4.216312e-12
GO:2000112 regulation of cellular macromolecule biosynthetic process 4.626647e-12
GO:0003002 regionalization 4.640743e-12
GO:0010557 positive regulation of macromolecule biosynthetic process 5.346222e-12
GO:0010468 regulation of gene expression 1.592862e-11
GO:0006355 regulation of transcription, DNA-dependent 1.671059e-11
GO:0007399 nervous system development 2.508773e-11
GO:0048706 embryonic skeletal system development 3.550123e-11
GO:0045892 negative regulation of transcription, DNA-dependent 3.928620e-11
GO:0031326 regulation of cellular biosynthetic process 4.125655e-11
GO:0070646 protein modification by small protein removal 4.268086e-11
GO:0051252 regulation of RNA metabolic process 4.688007e-11
GO:0010628 positive regulation of gene expression 4.936333e-11
GO:0048731 system development 5.165366e-11
GO:0045893 positive regulation of transcription, DNA-dependent 1.214685e-10
GO:0048598 embryonic morphogenesis 1.512925e-10
GO:0001501 skeletal system development 1.536620e-10
GO:0010629 negative regulation of gene expression 1.563173e-10
GO:0048705 skeletal system morphogenesis 1.662188e-10
GO:0021871 forebrain regionalization 1.964570e-10
GO:0010604 positive regulation of macromolecule metabolic process 2.679423e-10
GO:0051254 positive regulation of RNA metabolic process 2.697703e-10
GO:0009891 positive regulation of biosynthetic process 2.935619e-10
GO:0009889 regulation of biosynthetic process 2.941586e-10
GO:0031328 positive regulation of cellular biosynthetic process 3.170521e-10
GO:0048562 embryonic organ morphogenesis 4.278790e-10
GO:0051216 cartilage development 4.844395e-10
GO:0048568 embryonic organ development 6.060841e-10
GO:0051253 negative regulation of RNA metabolic process 6.099873e-10
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 8.198033e-10
GO:0030335 positive regulation of cell migration 1.074434e-9
GO:0007275 multicellular organismal development 1.224978e-9
GO:0031327 negative regulation of cellular biosynthetic process 1.857320e-9
GO:0007389 pattern specification process 1.995999e-9
GO:0032501 multicellular organismal process 2.667056e-9
GO:0010558 negative regulation of macromolecule biosynthetic process 3.353904e-9
GO:0051272 positive regulation of cellular component movement 3.823642e-9
GO:0009890 negative regulation of biosynthetic process 4.025278e-9
GO:0060255 regulation of macromolecule metabolic process 4.567905e-9
GO:0015816 glycine transport 4.643030e-9
GO:2000147 positive regulation of cell motility 5.934384e-9
GO:0048806 genitalia development 8.364312e-9
GO:0009888 tissue development 8.480229e-9
GO:0032879 regulation of localization 8.612022e-9
GO:0009653 anatomical structure morphogenesis 1.166641e-8
GO:2000113 negative regulation of cellular macromolecule biosynthetic process 1.234970e-8
GO:0009952 anterior/posterior pattern specification 1.256198e-8
GO:0001958 endochondral ossification 1.261359e-8
GO:0060348 bone development 1.721305e-8
GO:0045944 positive regulation of transcription from RNA polymerase II promoter 1.843327e-8
GO:0001957 intramembranous ossification 2.053106e-8
GO:0030154 cell differentiation 2.180412e-8
GO:0010646 regulation of cell communication 2.208893e-8
GO:0006351 transcription, DNA-dependent 2.259608e-8
GO:0032502 developmental process 2.727044e-8
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 2.886443e-8
GO:0040017 positive regulation of locomotion 2.918157e-8
GO:0032774 RNA biosynthetic process 2.949743e-8
GO:0051172 negative regulation of nitrogen compound metabolic process 2.956118e-8
GO:0060346 bone trabecula formation 3.285016e-8
GO:0048864 stem cell development 3.378308e-8
GO:0048704 embryonic skeletal system morphogenesis 3.758904e-8
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 3.854177e-8
GO:0015747 urate transport 4.166600e-8
GO:0030334 regulation of cell migration 4.419873e-8
GO:0048729 tissue morphogenesis 4.553420e-8
GO:0019219 regulation of nucleobase-containing compound metabolic process 5.530420e-8
GO:0002250 adaptive immune response 5.991932e-8
GO:0071229 cellular response to acid 6.013348e-8
GO:0048699 generation of neurons 6.324751e-8
GO:0031323 regulation of cellular metabolic process 7.784339e-8
GO:0080090 regulation of primary metabolic process 7.904652e-8
GO:0022008 neurogenesis 8.193877e-8
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 8.538312e-8
GO:0009893 positive regulation of metabolic process 8.900952e-8
GO:0051173 positive regulation of nitrogen compound metabolic process 9.107592e-8
GO:0034504 protein localization to nucleus 1.036863e-7
GO:0031325 positive regulation of cellular metabolic process 1.192377e-7
GO:0045165 cell fate commitment 1.335025e-7
GO:0042989 sequestering of actin monomers 1.483831e-7
GO:0001823 mesonephros development 1.513381e-7
GO:0051270 regulation of cellular component movement 1.517927e-7
GO:0048863 stem cell differentiation 1.589999e-7
GO:0048869 cellular developmental process 1.649006e-7
GO:0051171 regulation of nitrogen compound metabolic process 1.724741e-7
GO:0048523 negative regulation of cellular process 1.746567e-7
GO:0048856 anatomical structure development 1.781034e-7
GO:0070078 histone H3-R2 demethylation 2.164489e-7
GO:0070079 histone H4-R3 demethylation 2.164489e-7
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 2.164489e-7
GO:0050793 regulation of developmental process 2.181662e-7
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 2.558693e-7
GO:0040012 regulation of locomotion 2.674909e-7
GO:0072006 nephron development 2.733440e-7
GO:0045599 negative regulation of fat cell differentiation 3.054561e-7
GO:0019827 stem cell maintenance 3.327649e-7
GO:0001503 ossification 3.615842e-7
GO:0042346 positive regulation of NF-kappaB import into nucleus 4.073516e-7
GO:0009887 organ morphogenesis 4.418404e-7
GO:0048518 positive regulation of biological process 4.650838e-7
GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 4.931269e-7
GO:2000195 negative regulation of female gonad development 5.173098e-7
GO:0060675 ureteric bud morphogenesis 5.693975e-7
GO:0000904 cell morphogenesis involved in differentiation 6.190322e-7
GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 6.450420e-7
GO:0021993 initiation of neural tube closure 6.463690e-7
GO:0071230 cellular response to amino acid stimulus 6.676930e-7
GO:0048519 negative regulation of biological process 6.971235e-7
GO:2000145 regulation of cell motility 7.218607e-7
GO:0009953 dorsal/ventral pattern formation 8.394776e-7
GO:0048522 positive regulation of cellular process 8.515890e-7
GO:0060325 face morphogenesis 9.821287e-7
GO:0072236 metanephric loop of Henle development 1.019516e-6
GO:0033631 cell-cell adhesion mediated by integrin 1.084985e-6
GO:0050714 positive regulation of protein secretion 1.129553e-6
GO:0001658 branching involved in ureteric bud morphogenesis 1.352807e-6
GO:0033627 cell adhesion mediated by integrin 1.374222e-6
GO:0010893 positive regulation of steroid biosynthetic process 1.507233e-6
GO:0051492 regulation of stress fiber assembly 1.522608e-6
GO:0035272 exocrine system development 1.639113e-6
GO:0060993 kidney morphogenesis 1.701064e-6
GO:0071495 cellular response to endogenous stimulus 1.707807e-6
GO:0090005 negative regulation of establishment of protein localization in plasma membrane 1.783366e-6
GO:0045785 positive regulation of cell adhesion 1.854572e-6
GO:2001076 positive regulation of metanephric ureteric bud development 1.872160e-6
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 1.872160e-6
GO:0007356 thorax and anterior abdomen determination 1.872160e-6
GO:2000026 regulation of multicellular organismal development 1.897632e-6
GO:0072070 loop of Henle development 1.970264e-6
GO:0071418 cellular response to amine stimulus 1.974950e-6
GO:0006414 translational elongation 2.024078e-6
GO:0060376 positive regulation of mast cell differentiation 2.090922e-6
GO:0006606 protein import into nucleus 2.312756e-6
GO:0030155 regulation of cell adhesion 2.445789e-6
GO:0002883 regulation of hypersensitivity 2.462966e-6
GO:0030198 extracellular matrix organization 2.513790e-6
GO:0010718 positive regulation of epithelial to mesenchymal transition 2.560009e-6
GO:0030182 neuron differentiation 2.576578e-6
GO:0061005 cell differentiation involved in kidney development 2.583459e-6
GO:0032233 positive regulation of actin filament bundle assembly 2.595193e-6
GO:0002524 hypersensitivity 2.621443e-6
GO:0008284 positive regulation of cell proliferation 2.636274e-6
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 2.900281e-6
GO:0030520 estrogen receptor signaling pathway 3.080834e-6
GO:0015851 nucleobase transport 3.246201e-6
GO:0010595 positive regulation of endothelial cell migration 3.582775e-6
GO:0072075 metanephric mesenchyme development 3.713429e-6
GO:0030539 male genitalia development 3.716701e-6
GO:0010811 positive regulation of cell-substrate adhesion 3.992912e-6
GO:0071417 cellular response to organic nitrogen 4.113833e-6
GO:2000194 regulation of female gonad development 4.198141e-6
GO:0010594 regulation of endothelial cell migration 4.220808e-6
GO:0001656 metanephros development 4.456431e-6
GO:0021515 cell differentiation in spinal cord 4.662313e-6
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 4.885677e-6
GO:0010810 regulation of cell-substrate adhesion 4.925496e-6
GO:0051049 regulation of transport 4.983493e-6
GO:0051897 positive regulation of protein kinase B signaling cascade 5.050571e-6
GO:0035019 somatic stem cell maintenance 5.063810e-6
GO:0007435 salivary gland morphogenesis 5.129480e-6
GO:0072125 negative regulation of glomerular mesangial cell proliferation 5.277785e-6
GO:0051094 positive regulation of developmental process 5.297004e-6
GO:0072107 positive regulation of ureteric bud formation 5.397628e-6
GO:0071474 cellular hyperosmotic response 5.814134e-6
GO:0090031 positive regulation of steroid hormone biosynthetic process 5.837477e-6
GO:0006863 purine base transport 6.127426e-6
GO:0051093 negative regulation of developmental process 6.309682e-6
GO:0009790 embryo development 6.314411e-6
GO:0050794 regulation of cellular process 6.542788e-6
GO:0051170 nuclear import 6.833298e-6
GO:0045596 negative regulation of cell differentiation 6.927752e-6
GO:0030111 regulation of Wnt receptor signaling pathway 7.103410e-6
GO:0001657 ureteric bud development 7.537750e-6
GO:0072074 kidney mesenchyme development 7.554610e-6
GO:0021797 forebrain anterior/posterior pattern specification 7.587255e-6
GO:0060343 trabecula formation 7.642809e-6
GO:0000902 cell morphogenesis 7.768942e-6
GO:0032231 regulation of actin filament bundle assembly 8.466114e-6
GO:0051046 regulation of secretion 8.637794e-6
GO:0007431 salivary gland development 8.982576e-6
GO:0042127 regulation of cell proliferation 9.055611e-6
GO:0010389 regulation of G2/M transition of mitotic cell cycle 9.079424e-6
GO:0048812 neuron projection morphogenesis 9.255958e-6
GO:0010717 regulation of epithelial to mesenchymal transition 1.032232e-5
GO:0051239 regulation of multicellular organismal process 1.037505e-5
GO:0050789 regulation of biological process 1.073592e-5
GO:0072166 posterior mesonephric tubule development 1.091916e-5
GO:0071295 cellular response to vitamin 1.142797e-5
GO:0060173 limb development 1.349676e-5
GO:0045628 regulation of T-helper 2 cell differentiation 1.418418e-5
GO:0035411 catenin import into nucleus 1.450461e-5
GO:0045927 positive regulation of growth 1.457783e-5
GO:0045622 regulation of T-helper cell differentiation 1.463462e-5
GO:0070208 protein heterotrimerization 1.554363e-5
GO:2000242 negative regulation of reproductive process 1.555046e-5
GO:0050867 positive regulation of cell activation 1.556102e-5
GO:0048839 inner ear development 1.593808e-5
GO:0051222 positive regulation of protein transport 1.641811e-5
GO:0002449 lymphocyte mediated immunity 1.708644e-5
GO:0032754 positive regulation of interleukin-5 production 2.036125e-5
GO:0032237 activation of store-operated calcium channel activity 2.036125e-5
GO:0050863 regulation of T cell activation 2.082077e-5
GO:0048545 response to steroid hormone stimulus 2.087191e-5
GO:0046622 positive regulation of organ growth 2.105667e-5
GO:0007420 brain development 2.182155e-5
GO:0023051 regulation of signaling 2.212205e-5
GO:0072079 nephron tubule formation 2.244142e-5
GO:0035108 limb morphogenesis 2.278453e-5
GO:0072205 metanephric collecting duct development 2.400312e-5
GO:0051050 positive regulation of transport 2.503301e-5
GO:0032094 response to food 2.593810e-5
GO:0021953 central nervous system neuron differentiation 2.615805e-5
GO:2000273 positive regulation of receptor activity 2.692853e-5
GO:0046637 regulation of alpha-beta T cell differentiation 2.852795e-5
GO:0045787 positive regulation of cell cycle 2.854130e-5
GO:0043583 ear development 2.882423e-5
GO:0031670 cellular response to nutrient 3.007096e-5
GO:0050680 negative regulation of epithelial cell proliferation 3.059971e-5
GO:0060323 head morphogenesis 3.216446e-5
GO:2000602 regulation of interphase of mitotic cell cycle 3.281410e-5
GO:0072015 glomerular visceral epithelial cell development 3.459182e-5
GO:0071260 cellular response to mechanical stimulus 3.508449e-5
GO:0046129 purine ribonucleoside biosynthetic process 3.524974e-5
GO:0002885 positive regulation of hypersensitivity 3.586013e-5
GO:0032355 response to estradiol stimulus 3.601163e-5
GO:0017196 N-terminal peptidyl-methionine acetylation 3.606275e-5
GO:0002320 lymphoid progenitor cell differentiation 3.633530e-5
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 3.713085e-5
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 3.835546e-5
GO:0048513 organ development 3.904956e-5
GO:0019222 regulation of metabolic process 3.926770e-5
GO:0043524 negative regulation of neuron apoptosis 3.961365e-5
GO:0009161 ribonucleoside monophosphate metabolic process 3.981743e-5
GO:0008037 cell recognition 4.171446e-5
GO:0090183 regulation of kidney development 4.363524e-5
GO:0060389 pathway-restricted SMAD protein phosphorylation 4.387038e-5
GO:0030326 embryonic limb morphogenesis 4.422809e-5
GO:0072278 metanephric comma-shaped body morphogenesis 4.464347e-5
GO:0072284 metanephric S-shaped body morphogenesis 4.464347e-5
GO:0060429 epithelium development 4.470446e-5
GO:0045647 negative regulation of erythrocyte differentiation 4.482415e-5
GO:0071300 cellular response to retinoic acid 4.500304e-5
GO:0030900 forebrain development 4.696943e-5
GO:0072073 kidney epithelium development 4.934504e-5
GO:0032689 negative regulation of interferon-gamma production 4.956723e-5
GO:0002443 leukocyte mediated immunity 5.061838e-5
GO:0034505 tooth mineralization 5.220563e-5
GO:0009725 response to hormone stimulus 5.309844e-5
GO:0045750 positive regulation of S phase of mitotic cell cycle 5.373599e-5
GO:0006474 N-terminal protein amino acid acetylation 5.488000e-5
GO:0042345 regulation of NF-kappaB import into nucleus 5.780515e-5
GO:0046628 positive regulation of insulin receptor signaling pathway 5.918282e-5
GO:0034329 cell junction assembly 5.962513e-5
GO:0010720 positive regulation of cell development 6.029099e-5
GO:0035295 tube development 6.105484e-5
GO:0097039 protein linear polyubiquitination 6.294673e-5
GO:0046033 AMP metabolic process 6.318109e-5
GO:0072124 regulation of glomerular mesangial cell proliferation 6.409936e-5
GO:0032736 positive regulation of interleukin-13 production 6.409936e-5
GO:0060364 frontal suture morphogenesis 6.472999e-5
GO:0016331 morphogenesis of embryonic epithelium 6.574905e-5
GO:0072112 glomerular visceral epithelial cell differentiation 7.265484e-5
GO:0072170 metanephric tubule development 7.353971e-5
GO:0009892 negative regulation of metabolic process 7.452068e-5
GO:0048667 cell morphogenesis involved in neuron differentiation 7.466885e-5
GO:0051251 positive regulation of lymphocyte activation 7.632237e-5
GO:0033025 regulation of mast cell apoptosis 7.916855e-5
GO:0031324 negative regulation of cellular metabolic process 8.097536e-5
GO:0071072 negative regulation of phospholipid biosynthetic process 8.529120e-5
GO:0032835 glomerulus development 8.636901e-5
GO:0071299 cellular response to vitamin A 8.671120e-5
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 8.683630e-5
GO:0010605 negative regulation of macromolecule metabolic process 8.801587e-5
GO:0045629 negative regulation of T-helper 2 cell differentiation 8.892749e-5
GO:0030855 epithelial cell differentiation 8.994799e-5
GO:0002696 positive regulation of leukocyte activation 9.109384e-5
GO:0090030 regulation of steroid hormone biosynthetic process 9.184466e-5
GO:0002828 regulation of type 2 immune response 9.203432e-5
GO:0009167 purine ribonucleoside monophosphate metabolic process 9.537135e-5
GO:0048663 neuron fate commitment 9.582946e-5
GO:0007409 axonogenesis 9.679251e-5
GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide 9.691564e-5
GO:0007423 sensory organ development 9.811555e-5
GO:0032990 cell part morphogenesis 1.017211e-4
GO:0022612 gland morphogenesis 1.020033e-4
GO:0070231 T cell apoptosis 1.025909e-4
GO:0023035 CD40 signaling pathway 1.029882e-4
GO:0000722 telomere maintenance via recombination 1.029882e-4
GO:0001775 cell activation 1.043392e-4
GO:0045624 positive regulation of T-helper cell differentiation 1.093947e-4
GO:0072234 metanephric nephron tubule development 1.095009e-4
GO:0060231 mesenchymal to epithelial transition 1.095009e-4
GO:0002009 morphogenesis of an epithelium 1.107640e-4
GO:0030823 regulation of cGMP metabolic process 1.120587e-4
GO:0002861 regulation of inflammatory response to antigenic stimulus 1.152285e-4
GO:0060923 cardiac muscle cell fate commitment 1.154047e-4
GO:0072164 mesonephric tubule development 1.161582e-4
GO:0008361 regulation of cell size 1.170028e-4
GO:0045931 positive regulation of mitotic cell cycle 1.185500e-4
GO:2000467 positive regulation of glycogen (starch) synthase activity 1.215192e-4
GO:0048585 negative regulation of response to stimulus 1.218739e-4
GO:0032352 positive regulation of hormone metabolic process 1.241766e-4
GO:0048858 cell projection morphogenesis 1.253334e-4
GO:0042063 gliogenesis 1.253678e-4
GO:0072210 metanephric nephron development 1.293982e-4
GO:2000657 negative regulation of apolipoprotein binding 1.295569e-4
GO:0051496 positive regulation of stress fiber assembly 1.307006e-4
GO:0071214 cellular response to abiotic stimulus 1.315194e-4
GO:0021592 fourth ventricle development 1.355197e-4
GO:0034762 regulation of transmembrane transport 1.375439e-4
GO:0006366 transcription from RNA polymerase II promoter 1.437586e-4
GO:0051896 regulation of protein kinase B signaling cascade 1.492073e-4
GO:0071383 cellular response to steroid hormone stimulus 1.509860e-4
GO:0007154 cell communication 1.542014e-4
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 1.554114e-4
GO:0072001 renal system development 1.557493e-4
GO:0072080 nephron tubule development 1.587742e-4
GO:0002467 germinal center formation 1.594058e-4
GO:0051085 chaperone mediated protein folding requiring cofactor 1.595811e-4
GO:0043491 protein kinase B signaling cascade 1.618871e-4
GO:0007565 female pregnancy 1.661739e-4
GO:0043401 steroid hormone mediated signaling pathway 1.690395e-4
GO:0065007 biological regulation 1.696704e-4
GO:0001798 positive regulation of type IIa hypersensitivity 1.715729e-4
GO:0060690 epithelial cell differentiation involved in salivary gland development 1.753933e-4
GO:0002874 regulation of chronic inflammatory response to antigenic stimulus 1.753933e-4
GO:0048639 positive regulation of developmental growth 1.793179e-4
GO:0006646 phosphatidylethanolamine biosynthetic process 1.802353e-4
GO:0043410 positive regulation of MAPKKK cascade 1.879071e-4
GO:0032674 regulation of interleukin-5 production 1.931218e-4
GO:0007442 hindgut morphogenesis 1.946414e-4
GO:0061383 trabecula morphogenesis 2.042512e-4
GO:0002316 follicular B cell differentiation 2.072605e-4
GO:0010648 negative regulation of cell communication 2.161676e-4
GO:0060206 estrous cycle phase 2.177453e-4
GO:0014075 response to amine stimulus 2.227012e-4
GO:0060836 lymphatic endothelial cell differentiation 2.268516e-4
GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter 2.269143e-4
GO:0072363 regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter 2.269143e-4
GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter 2.269143e-4
GO:0048260 positive regulation of receptor-mediated endocytosis 2.301958e-4
GO:0007379 segment specification 2.304692e-4
GO:0001829 trophectodermal cell differentiation 2.366715e-4
GO:0002791 regulation of peptide secretion 2.374379e-4
GO:0072207 metanephric epithelium development 2.391204e-4
GO:0006909 phagocytosis 2.419177e-4
GO:0015711 organic anion transport 2.493745e-4
GO:0030825 positive regulation of cGMP metabolic process 2.499340e-4
GO:0010001 glial cell differentiation 2.530904e-4
GO:0051249 regulation of lymphocyte activation 2.555208e-4
GO:0023057 negative regulation of signaling 2.559265e-4
GO:0060324 face development 2.596665e-4
GO:0010543 regulation of platelet activation 2.601723e-4
GO:0060751 branch elongation involved in mammary gland duct branching 2.668053e-4
GO:0050865 regulation of cell activation 2.677738e-4
GO:0046898 response to cycloheximide 2.720056e-4
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.721760e-4
GO:0090189 regulation of branching involved in ureteric bud morphogenesis 2.733954e-4
GO:0001568 blood vessel development 2.741066e-4
GO:0001936 regulation of endothelial cell proliferation 2.756658e-4
GO:0060010 Sertoli cell fate commitment 2.776403e-4
GO:0045453 bone resorption 2.790737e-4
GO:0071071 regulation of phospholipid biosynthetic process 2.860826e-4
GO:0035148 tube formation 2.871331e-4
GO:0034616 response to laminar fluid shear stress 2.879580e-4
GO:0061326 renal tubule development 2.915788e-4
GO:0001649 osteoblast differentiation 2.934355e-4
GO:0045595 regulation of cell differentiation 2.962718e-4
GO:0060284 regulation of cell development 3.041300e-4
GO:0009967 positive regulation of signal transduction 3.080780e-4
GO:0050708 regulation of protein secretion 3.126811e-4
GO:0072179 nephric duct formation 3.127817e-4
GO:0001822 kidney development 3.171794e-4
GO:0046113 nucleobase catabolic process 3.177952e-4
GO:0001838 embryonic epithelial tube formation 3.193301e-4
GO:0007417 central nervous system development 3.220314e-4
GO:0006167 AMP biosynthetic process 3.259597e-4
GO:0006924 activation-induced cell death of T cells 3.272859e-4
GO:0046952 ketone body catabolic process 3.284189e-4
GO:0003097 renal water transport 3.314083e-4
GO:0072560 type B pancreatic cell maturation 3.340085e-4
GO:0018924 mandelate metabolic process 3.340085e-4
GO:0034405 response to fluid shear stress 3.349815e-4
GO:0046889 positive regulation of lipid biosynthetic process 3.373278e-4
GO:0072060 outer medullary collecting duct development 3.380943e-4
GO:0072061 inner medullary collecting duct development 3.380943e-4
GO:0032571 response to vitamin K 3.380943e-4
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 3.380943e-4
GO:0060363 cranial suture morphogenesis 3.393253e-4
GO:0042976 activation of Janus kinase activity 3.433186e-4
GO:0042637 catagen 3.433186e-4
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 3.455786e-4
GO:0008344 adult locomotory behavior 3.491194e-4
GO:0072028 nephron morphogenesis 3.550036e-4
GO:0000060 protein import into nucleus, translocation 3.589972e-4
GO:0048702 embryonic neurocranium morphogenesis 3.596319e-4
GO:0045321 leukocyte activation 3.626965e-4
GO:0060341 regulation of cellular localization 3.654503e-4
GO:2000018 regulation of male gonad development 3.656596e-4
GO:0007422 peripheral nervous system development 3.839251e-4
GO:0007346 regulation of mitotic cell cycle 3.868860e-4
GO:0002438 acute inflammatory response to antigenic stimulus 3.914267e-4
GO:0048619 embryonic hindgut morphogenesis 3.964842e-4
GO:0048732 gland development 3.991531e-4
GO:0045081 negative regulation of interleukin-10 biosynthetic process 4.004757e-4
GO:0002115 store-operated calcium entry 4.004757e-4
GO:0042116 macrophage activation 4.037786e-4
GO:0021510 spinal cord development 4.043797e-4
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 4.066148e-4
GO:0048625 myoblast cell fate commitment 4.067621e-4
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 4.092188e-4
GO:0007166 cell surface receptor linked signaling pathway 4.196759e-4
GO:0031668 cellular response to extracellular stimulus 4.467601e-4
GO:0010544 negative regulation of platelet activation 4.529835e-4
GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway 4.580575e-4
GO:0072175 epithelial tube formation 4.645345e-4
GO:0035826 rubidium ion transport 4.654278e-4
GO:2000682 positive regulation of rubidium ion transport 4.654278e-4
GO:2000688 positive regulation of rubidium ion transmembrane transporter activity 4.654278e-4
GO:0043252 sodium-independent organic anion transport 4.654278e-4
GO:0001682 tRNA 5'-leader removal 4.654278e-4
GO:0016078 tRNA catabolic process 4.654278e-4
GO:0021528 commissural neuron differentiation in spinal cord 4.654278e-4
GO:0071496 cellular response to external stimulus 4.714683e-4
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 4.760346e-4
GO:0048701 embryonic cranial skeleton morphogenesis 4.808925e-4
GO:0043627 response to estrogen stimulus 4.885137e-4
GO:2000020 positive regulation of male gonad development 4.943537e-4
GO:0006206 pyrimidine base metabolic process 4.972515e-4
GO:0050868 negative regulation of T cell activation 4.978260e-4
GO:0021678 third ventricle development 4.986079e-4
GO:0071470 cellular response to osmotic stress 4.986079e-4
GO:0051584 regulation of dopamine uptake 4.986079e-4
GO:0040013 negative regulation of locomotion 4.986573e-4
GO:0042307 positive regulation of protein import into nucleus 4.992675e-4
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 4.998232e-4
GO:0061046 regulation of branching involved in lung morphogenesis 5.234923e-4
GO:0060421 positive regulation of heart growth 5.234923e-4
GO:0009260 ribonucleotide biosynthetic process 5.245295e-4
GO:0002040 sprouting angiogenesis 5.283080e-4
GO:0031175 neuron projection development 5.324126e-4
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 5.476191e-4
GO:0051130 positive regulation of cellular component organization 5.491974e-4
GO:0043589 skin morphogenesis 5.602606e-4
GO:0071731 response to nitric oxide 5.605214e-4
GO:0060602 branch elongation of an epithelium 5.665451e-4
GO:0043434 response to peptide hormone stimulus 5.738173e-4
GO:0051798 positive regulation of hair follicle development 5.745626e-4
GO:0002064 epithelial cell development 5.803438e-4
GO:0070668 positive regulation of mast cell proliferation 5.839657e-4
GO:0046168 glycerol-3-phosphate catabolic process 5.839657e-4
GO:0030490 maturation of SSU-rRNA 5.892731e-4
GO:0048268 clathrin coat assembly 6.050282e-4
GO:0000302 response to reactive oxygen species 6.052410e-4
GO:0016064 immunoglobulin mediated immune response 6.076975e-4
GO:0032870 cellular response to hormone stimulus 6.119694e-4
GO:0051580 regulation of neurotransmitter uptake 6.129669e-4
GO:0072240 metanephric DCT cell differentiation 6.156268e-4
GO:0072227 metanephric macula densa development 6.156268e-4
GO:0051451 myoblast migration 6.156268e-4
GO:0032096 negative regulation of response to food 6.218592e-4
GO:0001764 neuron migration 6.312556e-4
GO:0071805 potassium ion transmembrane transport 6.345542e-4
GO:0003338 metanephros morphogenesis 6.368097e-4
GO:0046649 lymphocyte activation 6.447456e-4
GO:0043010 camera-type eye development 6.471194e-4
GO:0034765 regulation of ion transmembrane transport 6.504331e-4
GO:0032526 response to retinoic acid 6.694096e-4
GO:0060482 lobar bronchus development 6.720803e-4
GO:0002052 positive regulation of neuroblast proliferation 6.734878e-4
GO:0090276 regulation of peptide hormone secretion 6.755760e-4
GO:0060014 granulosa cell differentiation 6.778288e-4
GO:0000189 MAPK import into nucleus 6.841229e-4
GO:0018206 peptidyl-methionine modification 6.841229e-4
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 6.916144e-4
GO:0014070 response to organic cyclic compound 6.958091e-4
GO:0055123 digestive system development 7.012663e-4
GO:0008286 insulin receptor signaling pathway 7.047111e-4
GO:0042993 positive regulation of transcription factor import into nucleus 7.059898e-4
GO:0071310 cellular response to organic substance 7.161254e-4
GO:0035249 synaptic transmission, glutamatergic 7.236566e-4
GO:0043299 leukocyte degranulation 7.243387e-4
GO:0051930 regulation of sensory perception of pain 7.254198e-4
GO:0023052 signaling 7.282189e-4
GO:0001654 eye development 7.344891e-4
GO:0045597 positive regulation of cell differentiation 7.506882e-4
GO:0009991 response to extracellular stimulus 7.525334e-4
GO:0019724 B cell mediated immunity 7.625622e-4
GO:0009968 negative regulation of signal transduction 7.649789e-4
GO:0035239 tube morphogenesis 7.745606e-4
GO:0006901 vesicle coating 7.823509e-4
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 7.840157e-4
GO:0070345 negative regulation of fat cell proliferation 7.840157e-4
GO:0009637 response to blue light 7.840157e-4
GO:0060299 negative regulation of sarcomere organization 7.840157e-4