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Novel motif:89

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name:motif89_CGCCGTGTTTA

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0030163 protein catabolic process 2.917675e-12
GO:0006369 termination of RNA polymerase II transcription 5.492613e-12
GO:0010498 proteasomal protein catabolic process 2.911334e-11
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 2.988052e-11
GO:0006353 transcription termination, DNA-dependent 4.443083e-11
GO:0051603 proteolysis involved in cellular protein catabolic process 6.675499e-11
GO:0044257 cellular protein catabolic process 1.201813e-10
GO:0007620 copulation 2.991707e-10
GO:0016070 RNA metabolic process 9.846117e-10
GO:0035461 vitamin transmembrane transport 1.378126e-9
GO:0034393 positive regulation of smooth muscle cell apoptosis 1.438149e-9
GO:0006511 ubiquitin-dependent protein catabolic process 2.759793e-9
GO:0019941 modification-dependent protein catabolic process 3.497639e-9
GO:0010467 gene expression 7.780495e-9
GO:0043382 positive regulation of memory T cell differentiation 8.464510e-9
GO:0043632 modification-dependent macromolecule catabolic process 9.056663e-9
GO:0090085 regulation of protein deubiquitination 9.366586e-9
GO:0006231 dTMP biosynthetic process 1.220672e-8
GO:0019088 immortalization of host cell by virus 1.220672e-8
GO:0006396 RNA processing 1.792419e-8
GO:0090086 negative regulation of protein deubiquitination 2.457225e-8
GO:0044265 cellular macromolecule catabolic process 3.232167e-8
GO:0000209 protein polyubiquitination 3.666189e-8
GO:0090304 nucleic acid metabolic process 4.671644e-8
GO:0006379 mRNA cleavage 5.623299e-8
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 6.260317e-8
GO:0001916 positive regulation of T cell mediated cytotoxicity 1.823313e-7
GO:0007618 mating 2.192872e-7
GO:0016071 mRNA metabolic process 2.225550e-7
GO:0019087 transformation of host cell by virus 2.580552e-7
GO:0035722 interleukin-12-mediated signaling pathway 3.174431e-7
GO:0009057 macromolecule catabolic process 3.581264e-7
GO:0033326 cerebrospinal fluid secretion 5.602447e-7
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 5.864838e-7
GO:0006397 mRNA processing 6.368725e-7
GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein 7.870449e-7
GO:0030433 ER-associated protein catabolic process 8.518091e-7
GO:0000398 nuclear mRNA splicing, via spliceosome 8.574576e-7
GO:0019048 virus-host interaction 8.830598e-7
GO:0007320 insemination 1.028559e-6
GO:0046078 dUMP metabolic process 1.098108e-6
GO:2000330 positive regulation of T-helper 17 cell lineage commitment 1.120774e-6
GO:2000318 positive regulation of T-helper 17 type immune response 1.120774e-6
GO:0044260 cellular macromolecule metabolic process 1.275557e-6
GO:0006325 chromatin organization 1.352451e-6
GO:0071934 thiamine transmembrane transport 1.410649e-6
GO:0034391 regulation of smooth muscle cell apoptosis 1.484591e-6
GO:0035357 peroxisome proliferator activated receptor signaling pathway 1.628462e-6
GO:0060574 intestinal epithelial cell maturation 1.860711e-6
GO:0051290 protein heterotetramerization 2.376018e-6
GO:0031639 plasminogen activation 2.553101e-6
GO:0006535 cysteine biosynthetic process from serine 2.658357e-6
GO:0019346 transsulfuration 2.658357e-6
GO:0043418 homocysteine catabolic process 2.658357e-6
GO:0019343 cysteine biosynthetic process via cystathionine 2.658357e-6
GO:0097045 phosphatidylserine exposure on blood platelet 3.008074e-6
GO:0000375 RNA splicing, via transesterification reactions 3.523326e-6
GO:0090141 positive regulation of mitochondrial fission 4.463922e-6
GO:0050689 negative regulation of defense response to virus by host 4.936723e-6
GO:0009798 axis specification 4.978126e-6
GO:0032915 positive regulation of transforming growth factor beta2 production 6.146701e-6
GO:0008380 RNA splicing 6.251029e-6
GO:0007494 midgut development 6.453615e-6
GO:0043484 regulation of RNA splicing 6.813002e-6
GO:0030970 retrograde protein transport, ER to cytosol 7.485501e-6
GO:0000077 DNA damage checkpoint 8.968267e-6
GO:0006351 transcription, DNA-dependent 1.072572e-5
GO:0032534 regulation of microvillus assembly 1.088895e-5
GO:0051443 positive regulation of ubiquitin-protein ligase activity 1.127327e-5
GO:0048319 axial mesoderm morphogenesis 1.140387e-5
GO:0031102 neuron projection regeneration 1.202165e-5
GO:0009163 nucleoside biosynthetic process 1.219858e-5
GO:0051865 protein autoubiquitination 1.651740e-5
GO:0016568 chromatin modification 1.883636e-5
GO:0010661 positive regulation of muscle cell apoptosis 2.008360e-5
GO:0016598 protein arginylation 2.050577e-5
GO:0019376 galactolipid catabolic process 2.229966e-5
GO:0065002 intracellular protein transmembrane transport 2.229966e-5
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 2.240387e-5
GO:0006684 sphingomyelin metabolic process 2.287663e-5
GO:0031570 DNA integrity checkpoint 2.344302e-5
GO:0071674 mononuclear cell migration 2.403061e-5
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 2.439429e-5
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 2.439429e-5
GO:0006139 nucleobase-containing compound metabolic process 2.613450e-5
GO:0006556 S-adenosylmethionine biosynthetic process 3.098514e-5
GO:0042977 activation of JAK2 kinase activity 3.244135e-5
GO:0045090 retroviral genome replication 3.438709e-5
GO:0046985 positive regulation of hemoglobin biosynthetic process 3.438709e-5
GO:0043973 histone H3-K4 acetylation 3.438709e-5
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 3.438709e-5
GO:0030185 nitric oxide transport 3.763925e-5
GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint 3.827180e-5
GO:0032774 RNA biosynthetic process 4.492829e-5
GO:0090140 regulation of mitochondrial fission 4.578783e-5
GO:0019448 L-cysteine catabolic process 4.627296e-5
GO:0009162 deoxyribonucleoside monophosphate metabolic process 4.784029e-5
GO:0006335 DNA replication-dependent nucleosome assembly 4.784029e-5
GO:0002069 columnar/cuboidal epithelial cell maturation 5.943350e-5
GO:0006406 mRNA export from nucleus 6.249775e-5
GO:0031124 mRNA 3'-end processing 6.529377e-5
GO:0010224 response to UV-B 7.068311e-5
GO:0010506 regulation of autophagy 7.198184e-5
GO:0046683 response to organophosphorus 7.258925e-5
GO:0006400 tRNA modification 7.814091e-5
GO:0042503 tyrosine phosphorylation of Stat3 protein 8.027722e-5
GO:0000387 spliceosomal snRNP assembly 8.149822e-5
GO:0010821 regulation of mitochondrion organization 8.257060e-5
GO:0034644 cellular response to UV 8.465138e-5
GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway 8.651199e-5
GO:0060248 detection of cell density by contact stimulus involved in contact inhibition 8.651199e-5
GO:0072285 mesenchymal to epithelial transition involved in metanephric renal vesicle formation 8.651199e-5
GO:0006427 histidyl-tRNA aminoacylation 8.651199e-5
GO:0045358 negative regulation of interferon-beta biosynthetic process 8.651199e-5
GO:0007371 ventral midline determination 8.651199e-5
GO:0051932 synaptic transmission, GABAergic 8.951793e-5
GO:0000073 spindle pole body separation 8.951793e-5
GO:0008616 queuosine biosynthetic process 8.951793e-5
GO:0019374 galactolipid metabolic process 9.193575e-5
GO:0048102 autophagic cell death 9.296942e-5
GO:0060658 nipple morphogenesis 9.296942e-5
GO:0071779 G1/S transition checkpoint 9.348068e-5
GO:0071482 cellular response to light stimulus 9.823322e-5
GO:0051351 positive regulation of ligase activity 1.028060e-4
GO:0045626 negative regulation of T-helper 1 cell differentiation 1.062153e-4
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.094985e-4
GO:0070842 aggresome assembly 1.100684e-4
GO:0009399 nitrogen fixation 1.202385e-4
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 1.232023e-4
GO:0032530 regulation of microvillus organization 1.298280e-4
GO:0072404 signal transduction involved in G1/S transition checkpoint 1.318132e-4
GO:0042770 signal transduction in response to DNA damage 1.433141e-4
GO:0048318 axial mesoderm development 1.503090e-4
GO:0031123 RNA 3'-end processing 1.516388e-4
GO:0031575 mitotic cell cycle G1/S transition checkpoint 1.553433e-4
GO:0044332 Wnt receptor signaling pathway involved in dorsal/ventral axis specification 1.562475e-4
GO:0006333 chromatin assembly or disassembly 1.645833e-4
GO:0072395 signal transduction involved in cell cycle checkpoint 1.763131e-4
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.776218e-4
GO:0070814 hydrogen sulfide biosynthetic process 1.785170e-4
GO:0070079 histone H4-R3 demethylation 1.845981e-4
GO:0070078 histone H3-R2 demethylation 1.845981e-4
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 1.845981e-4
GO:0035279 mRNA cleavage involved in gene silencing by miRNA 1.880287e-4
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.896465e-4
GO:0043249 erythrocyte maturation 1.899344e-4
GO:0045736 negative regulation of cyclin-dependent protein kinase activity 1.919151e-4
GO:0070671 response to interleukin-12 1.964962e-4
GO:2000045 regulation of G1/S transition of mitotic cell cycle 2.019412e-4
GO:0007031 peroxisome organization 2.041505e-4
GO:0034063 stress granule assembly 2.082529e-4
GO:0007339 binding of sperm to zona pellucida 2.189715e-4
GO:0055107 Golgi to secretory granule transport 2.274686e-4
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 2.318327e-4
GO:0015887 pantothenate transmembrane transport 2.329301e-4
GO:0015878 biotin transport 2.329301e-4
GO:0070986 left/right axis specification 2.427837e-4
GO:0018872 arsonoacetate metabolic process 2.459977e-4
GO:0031103 axon regeneration 2.496405e-4
GO:0032700 negative regulation of interleukin-17 production 2.646527e-4
GO:0046128 purine ribonucleoside metabolic process 2.738417e-4
GO:0035329 hippo signaling cascade 2.756941e-4
GO:0090083 regulation of inclusion body assembly 2.800277e-4
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 2.902848e-4
GO:0031638 zymogen activation 2.925238e-4
GO:0010455 positive regulation of cell fate commitment 2.925238e-4
GO:0006268 DNA unwinding involved in replication 2.925238e-4
GO:0072422 signal transduction involved in DNA damage checkpoint 3.076841e-4
GO:0006481 C-terminal protein methylation 3.157027e-4
GO:0044237 cellular metabolic process 3.179329e-4
GO:0010507 negative regulation of autophagy 3.345109e-4
GO:0050652 dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 3.520559e-4
GO:0090138 regulation of actin cytoskeleton organization by cell-cell adhesion 3.520559e-4
GO:0035409 histone H3-Y41 phosphorylation 3.616114e-4
GO:0008636 activation of caspase activity by protein phosphorylation 3.616114e-4
GO:0035771 interleukin-4-mediated signaling pathway 3.682396e-4
GO:0050691 regulation of defense response to virus by host 3.935261e-4
GO:0060286 flagellar cell motility 3.945061e-4
GO:0001555 oocyte growth 3.945061e-4
GO:0043471 regulation of cellular carbohydrate catabolic process 4.030640e-4
GO:0048280 vesicle fusion with Golgi apparatus 4.047235e-4
GO:0071415 cellular response to purine-containing compound 4.110780e-4
GO:0051383 kinetochore organization 4.125364e-4
GO:0000075 cell cycle checkpoint 4.151692e-4
GO:0051438 regulation of ubiquitin-protein ligase activity 4.188790e-4
GO:0010824 regulation of centrosome duplication 4.239213e-4
GO:0090084 negative regulation of inclusion body assembly 4.311388e-4
GO:0021587 cerebellum morphogenesis 4.498727e-4
GO:0034641 cellular nitrogen compound metabolic process 4.537576e-4
GO:0070647 protein modification by small protein conjugation or removal 4.597454e-4
GO:0006281 DNA repair 4.822696e-4
GO:0015671 oxygen transport 4.872318e-4
GO:0009956 radial pattern formation 4.941545e-4
GO:0061084 negative regulation of protein refolding 4.941545e-4
GO:0009992 cellular water homeostasis 5.039700e-4
GO:0016567 protein ubiquitination 5.123176e-4
GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway 5.285851e-4
GO:0006807 nitrogen compound metabolic process 5.408140e-4
GO:0046796 viral genome transport in host cell 5.434777e-4
GO:0046314 phosphocreatine biosynthetic process 5.435998e-4
GO:0010734 negative regulation of protein glutathionylation 5.441229e-4
GO:0050687 negative regulation of defense response to virus 5.648335e-4
GO:0060981 cell migration involved in coronary angiogenesis 6.398399e-4
GO:0071670 smooth muscle cell chemotaxis 6.398399e-4
GO:0060823 canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation 6.398399e-4
GO:0001575 globoside metabolic process 6.398399e-4
GO:0035752 lysosomal lumen pH elevation 6.398399e-4
GO:0000046 autophagic vacuole fusion 6.398399e-4
GO:0006413 translational initiation 6.539170e-4
GO:0006119 oxidative phosphorylation 6.622669e-4
GO:0009051 pentose-phosphate shunt, oxidative branch 6.718403e-4
GO:0042278 purine nucleoside metabolic process 7.139472e-4
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 7.151121e-4
GO:0000278 mitotic cell cycle 7.306630e-4
GO:0051148 negative regulation of muscle cell differentiation 7.328796e-4
GO:0043380 regulation of memory T cell differentiation 7.485864e-4
GO:0010624 regulation of Schwann cell proliferation 7.525882e-4
GO:0021797 forebrain anterior/posterior pattern specification 7.578937e-4
GO:0060687 regulation of branching involved in prostate gland morphogenesis 7.864416e-4
GO:0010822 positive regulation of mitochondrion organization 7.899378e-4
GO:0042976 activation of Janus kinase activity 8.051360e-4
GO:0090197 positive regulation of chemokine secretion 8.185544e-4
GO:0060836 lymphatic endothelial cell differentiation 8.237307e-4
GO:0060419 heart growth 8.295112e-4
GO:0032479 regulation of type I interferon production 8.351309e-4
GO:2000573 positive regulation of DNA biosynthetic process 8.862030e-4
GO:0070936 protein K48-linked ubiquitination 8.898741e-4
GO:0035036 sperm-egg recognition 8.913654e-4
GO:0033630 positive regulation of cell adhesion mediated by integrin 9.124198e-4
GO:0045653 negative regulation of megakaryocyte differentiation 9.399324e-4
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.837911e-4
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.837911e-4
GO:0034401 regulation of transcription by chromatin organization 1.005955e-3
GO:0034728 nucleosome organization 1.025777e-3
GO:0009436 glyoxylate catabolic process 1.031745e-3
GO:0043308 eosinophil degranulation 1.062559e-3
GO:0009234 menaquinone biosynthetic process 1.062559e-3
GO:0030827 negative regulation of cGMP biosynthetic process 1.062559e-3
GO:0034695 response to prostaglandin E stimulus 1.069767e-3
GO:0051568 histone H3-K4 methylation 1.079552e-3
GO:0046984 regulation of hemoglobin biosynthetic process 1.106714e-3
GO:0046129 purine ribonucleoside biosynthetic process 1.106777e-3
GO:0051329 interphase of mitotic cell cycle 1.157727e-3
GO:0043392 negative regulation of DNA binding 1.188583e-3
GO:0007498 mesoderm development 1.199193e-3
GO:0070417 cellular response to cold 1.232850e-3
GO:0042396 phosphagen biosynthetic process 1.239788e-3
GO:0032275 luteinizing hormone secretion 1.297149e-3
GO:0046884 follicle-stimulating hormone secretion 1.297149e-3
GO:0032785 negative regulation of transcription elongation, DNA-dependent 1.309938e-3
GO:0002711 positive regulation of T cell mediated immunity 1.318723e-3
GO:0051301 cell division 1.330112e-3
GO:0046605 regulation of centrosome cycle 1.342621e-3
GO:0042373 vitamin K metabolic process 1.343216e-3
GO:0009411 response to UV 1.407301e-3
GO:0051028 mRNA transport 1.423881e-3
GO:0016242 negative regulation of macroautophagy 1.448142e-3
GO:0070060 'de novo' actin filament nucleation 1.448142e-3
GO:0032648 regulation of interferon-beta production 1.483431e-3
GO:0031497 chromatin assembly 1.513584e-3
GO:0048024 regulation of nuclear mRNA splicing, via spliceosome 1.562175e-3
GO:0060242 contact inhibition 1.601298e-3
GO:0034723 DNA replication-dependent nucleosome organization 1.601298e-3
GO:0046500 S-adenosylmethionine metabolic process 1.607765e-3
GO:0050684 regulation of mRNA processing 1.608205e-3
GO:0043984 histone H4-K16 acetylation 1.614718e-3
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 1.635458e-3
GO:0001840 neural plate development 1.635971e-3
GO:0006334 nucleosome assembly 1.662678e-3
GO:0071824 protein-DNA complex subunit organization 1.670189e-3
GO:0031023 microtubule organizing center organization 1.703270e-3
GO:0001920 negative regulation of receptor recycling 1.760950e-3
GO:0060972 left/right pattern formation 1.775176e-3
GO:0071233 cellular response to leucine 1.775238e-3
GO:0042772 DNA damage response, signal transduction resulting in transcription 1.786713e-3
GO:0016570 histone modification 1.798571e-3
GO:0007009 plasma membrane organization 1.810806e-3
GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis 1.824842e-3
GO:0033632 regulation of cell-cell adhesion mediated by integrin 1.836859e-3
GO:0051340 regulation of ligase activity 1.841877e-3
GO:0090196 regulation of chemokine secretion 1.843549e-3
GO:0009116 nucleoside metabolic process 1.866844e-3
GO:0060648 mammary gland bud morphogenesis 1.878739e-3
GO:0032446 protein modification by small protein conjugation 1.906286e-3
GO:0033148 positive regulation of estrogen receptor signaling pathway 1.936720e-3
GO:0010626 negative regulation of Schwann cell proliferation 1.950886e-3
GO:0051325 interphase 1.982992e-3
GO:0006403 RNA localization 2.030992e-3
GO:0051276 chromosome organization 2.041796e-3
GO:0060038 cardiac muscle cell proliferation 2.048121e-3
GO:0071954 chemokine (C-C motif) ligand 11 production 2.055747e-3
GO:2000525 positive regulation of T cell costimulation 2.055747e-3
GO:0002215 defense response to nematode 2.055747e-3
GO:0035712 T-helper 2 cell activation 2.055747e-3
GO:0035709 memory T cell activation 2.055747e-3
GO:0035708 interleukin-4-dependent isotype switching to IgE isotypes 2.055747e-3
GO:0009950 dorsal/ventral axis specification 2.056779e-3
GO:0060973 cell migration involved in heart development 2.078230e-3
GO:0070103 regulation of interleukin-6-mediated signaling pathway 2.093092e-3
GO:0046134 pyrimidine nucleoside biosynthetic process 2.129784e-3
GO:0072348 sulfur compound transport 2.146722e-3
GO:0001914 regulation of T cell mediated cytotoxicity 2.176565e-3
GO:0034645 cellular macromolecule biosynthetic process 2.181547e-3
GO:0006405 RNA export from nucleus 2.190764e-3
GO:0060399 positive regulation of growth hormone receptor signaling pathway 2.209289e-3
GO:0046108 uridine metabolic process 2.209289e-3
GO:0033634 positive regulation of cell-cell adhesion mediated by integrin 2.236040e-3
GO:0042398 cellular modified amino acid biosynthetic process 2.260858e-3
GO:0002067 glandular epithelial cell differentiation 2.281237e-3
GO:0015910 peroxisomal long-chain fatty acid import 2.315172e-3
GO:0016569 covalent chromatin modification 2.348495e-3
GO:0022618 ribonucleoprotein complex assembly 2.371052e-3
GO:0048320 axial mesoderm formation 2.382307e-3
GO:0060921 sinoatrial node cell differentiation 2.526629e-3
GO:0060975 cardioblast migration to the midline involved in heart field formation 2.526629e-3
GO:0042664 negative regulation of endodermal cell fate specification 2.526629e-3
GO:0071799 cellular response to prostaglandin D stimulus 2.526629e-3
GO:0003236 sinus venosus morphogenesis 2.526629e-3
GO:0003210 cardiac atrium formation 2.526629e-3
GO:0035481 positive regulation of Notch signaling pathway involved in heart induction 2.526629e-3
GO:0003241 growth involved in heart morphogenesis 2.526629e-3
GO:0003259 cardioblast anterior-lateral migration 2.526629e-3
GO:0051444 negative regulation of ubiquitin-protein ligase activity 2.537170e-3
GO:0035881 amacrine cell differentiation 2.621034e-3
GO:0019344 cysteine biosynthetic process 2.766599e-3
GO:0051252 regulation of RNA metabolic process 2.814916e-3
GO:0051454 intracellular pH elevation 2.830152e-3
GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis 2.884129e-3
GO:2000249 regulation of actin cytoskeleton reorganization 2.897319e-3
GO:0051135 positive regulation of NK T cell activation 2.900701e-3
GO:0006098 pentose-phosphate shunt 2.974870e-3
GO:0034048 negative regulation of protein phosphatase type 2A activity 2.985678e-3
GO:0060649 mammary gland bud elongation 3.056451e-3
GO:0060659 nipple sheath formation 3.056451e-3
GO:0034660 ncRNA metabolic process 3.237417e-3
GO:0030330 DNA damage response, signal transduction by p53 class mediator 3.266330e-3
GO:0006683 galactosylceramide catabolic process 3.283801e-3
GO:0035372 protein localization to microtubule 3.283801e-3
GO:0002051 osteoblast fate commitment 3.318422e-3
GO:0032329 serine transport 3.331759e-3
GO:0042088 T-helper 1 type immune response 3.335155e-3
GO:0042832 defense response to protozoan 3.344409e-3
GO:0018205 peptidyl-lysine modification 3.366975e-3
GO:0034968 histone lysine methylation 3.412159e-3
GO:0071156 regulation of cell cycle arrest 3.416084e-3
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 3.434392e-3
GO:0009303 rRNA transcription 3.460951e-3
GO:0060124 positive regulation of growth hormone secretion 3.490147e-3
GO:0046599 regulation of centriole replication 3.597092e-3
GO:0003002 regionalization 3.660291e-3
GO:0006189 'de novo' IMP biosynthetic process 3.763033e-3
GO:0042775 mitochondrial ATP synthesis coupled electron transport 3.774907e-3
GO:0010610 regulation of mRNA stability involved in response to stress 3.795213e-3
GO:0009231 riboflavin biosynthetic process 3.795213e-3
GO:0006974 response to DNA damage stimulus 3.818179e-3
GO:0006386 termination of RNA polymerase III transcription 3.826805e-3
GO:0006385 transcription elongation from RNA polymerase III promoter 3.826805e-3
GO:0051583 dopamine uptake 3.872953e-3
GO:0070105 positive regulation of interleukin-6-mediated signaling pathway 4.011040e-3
GO:0034243 regulation of transcription elongation from RNA polymerase II promoter 4.027110e-3
GO:0000079 regulation of cyclin-dependent protein kinase activity 4.037674e-3
GO:0019693 ribose phosphate metabolic process 4.062799e-3
GO:0006463 steroid hormone receptor complex assembly 4.096976e-3
GO:0090007 regulation of mitotic anaphase 4.148279e-3
GO:0051488 activation of anaphase-promoting complex activity 4.155385e-3
GO:0042506 tyrosine phosphorylation of Stat5 protein 4.155385e-3
GO:0016573 histone acetylation 4.174229e-3
GO:0033628 regulation of cell adhesion mediated by integrin 4.183277e-3
GO:0010660 regulation of muscle cell apoptosis 4.233965e-3
GO:0031398 positive regulation of protein ubiquitination 4.292881e-3
GO:0033145 positive regulation of steroid hormone receptor signaling pathway 4.308098e-3
GO:0001839 neural plate morphogenesis 4.381822e-3
GO:0040015 negative regulation of multicellular organism growth 4.387886e-3
GO:0009059 macromolecule biosynthetic process 4.501488e-3
GO:0035196 production of miRNAs involved in gene silencing by miRNA 4.538273e-3
GO:0002230 positive regulation of defense response to virus by host 4.642215e-3
GO:0006825 copper ion transport 4.642864e-3
GO:0006681 galactosylceramide metabolic process 4.680322e-3
GO:0010715 regulation of extracellular matrix disassembly 4.693033e-3
GO:0000422 mitochondrion degradation 4.711431e-3
GO:0009119 ribonucleoside metabolic process 4.883497e-3
GO:0070358 actin polymerization-dependent cell motility 4.974740e-3
GO:0060058 positive regulation of apoptosis involved in mammary gland involution 4.978485e-3
GO:0035089 establishment of apical/basal cell polarity 5.159540e-3
GO:0090399 replicative senescence 5.167855e-3
GO:0001562 response to protozoan 5.181786e-3
GO:0048384 retinoic acid receptor signaling pathway 5.234736e-3
GO:0007093 mitotic cell cycle checkpoint 5.263710e-3
GO:0000956 nuclear-transcribed mRNA catabolic process 5.302790e-3
GO:0051169 nuclear transport 5.307243e-3
GO:0060235 lens induction in camera-type eye 5.356107e-3
GO:0051154 negative regulation of striated muscle cell differentiation 5.393819e-3
GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process 5.395125e-3
GO:0090344 negative regulation of cell aging 5.422267e-3
GO:0033146 regulation of estrogen receptor signaling pathway 5.448419e-3
GO:0032816 positive regulation of natural killer cell activation 5.448419e-3
GO:0055017 cardiac muscle tissue growth 5.499484e-3
GO:0071353 cellular response to interleukin-4 5.648301e-3
GO:0017121 phospholipid scrambling 5.677251e-3
GO:0014060 regulation of epinephrine secretion 5.688781e-3
GO:0003219 cardiac right ventricle formation 5.688781e-3
GO:0071826 ribonucleoprotein complex subunit organization 5.738011e-3
GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process 5.902499e-3
GO:0000088 mitotic prophase 5.902499e-3
GO:0035195 gene silencing by miRNA 5.952832e-3
GO:0032876 negative regulation of DNA endoreduplication 6.083662e-3
GO:0006110 regulation of glycolysis 6.102687e-3
GO:0006913 nucleocytoplasmic transport 6.104982e-3
GO:0046952 ketone body catabolic process 6.136440e-3
GO:0044273 sulfur compound catabolic process 6.153033e-3
GO:0042363 fat-soluble vitamin catabolic process 6.180540e-3
GO:0046950 cellular ketone body metabolic process 6.203828e-3
GO:0006868 glutamine transport 6.203828e-3
GO:0033600 negative regulation of mammary gland epithelial cell proliferation 6.230215e-3
GO:0007509 mesoderm migration involved in gastrulation 6.235582e-3
GO:0006298 mismatch repair 6.359135e-3
GO:0042727 flavin-containing compound biosynthetic process 6.392163e-3
GO:0001830 trophectodermal cell fate commitment 6.392163e-3
GO:0034314 Arp2/3 complex-mediated actin nucleation 6.392163e-3
GO:0045793 positive regulation of cell size 6.493870e-3
GO:0065004 protein-DNA complex assembly 6.516658e-3
GO:0040040 thermosensory behavior 6.661182e-3
GO:0051168 nuclear export 6.665112e-3
GO:0006206 pyrimidine base metabolic process 6.673129e-3
GO:0051182 coenzyme transport 6.750930e-3
GO:0000080 G1 phase of mitotic cell cycle 6.860748e-3
GO:0016571 histone methylation 6.898084e-3
GO:0032811 negative regulation of epinephrine secretion 6.899179e-3
GO:0035265 organ growth 6.961623e-3
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 6.977311e-3
GO:0006565 L-serine catabolic process 6.990212e-3
GO:0000715 nucleotide-excision repair, DNA damage recognition 7.078392e-3
GO:0009948 anterior/posterior axis specification 7.104494e-3
GO:0042723 thiamine-containing compound metabolic process 7.482825e-3
GO:0018065 protein-cofactor linkage 7.508391e-3
GO:0006355 regulation of transcription, DNA-dependent 7.517115e-3
GO:0051297 centrosome organization 7.584535e-3
GO:0018394 peptidyl-lysine acetylation 7.588391e-3
GO:0042093 T-helper cell differentiation 7.623723e-3
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 7.629009e-3
GO:0007253 cytoplasmic sequestering of NF-kappaB 7.692825e-3
GO:0048368 lateral mesoderm development 7.703619e-3
GO:0006740 NADPH regeneration 7.800377e-3
GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment 7.862849e-3
GO:0046951 ketone body biosynthetic process 7.911793e-3
GO:0042637 catagen 7.911793e-3
GO:0032383 regulation of intracellular cholesterol transport 7.916157e-3
GO:0070918 production of small RNA involved in gene silencing by RNA 7.923203e-3
GO:0042418 epinephrine biosynthetic process 8.004614e-3
GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA 8.004614e-3
GO:0021933 radial glia guided migration of cerebellar granule cell 8.004614e-3
GO:0006585 dopamine biosynthetic process from tyrosine 8.004614e-3
GO:0043170 macromolecule metabolic process 8.025472e-3
GO:0060427 lung connective tissue development 8.070229e-3
GO:0032070 regulation of deoxyribonuclease activity 8.070229e-3
GO:0015680 intracellular copper ion transport 8.070229e-3
GO:0032474 otolith morphogenesis 8.088591e-3
GO:0031119 tRNA pseudouridine synthesis 8.088591e-3
GO:0060398 regulation of growth hormone receptor signaling pathway 8.125354e-3
GO:0043585 nose morphogenesis 8.176199e-3
GO:0030823 regulation of cGMP metabolic process 8.217229e-3
GO:0060206 estrous cycle phase 8.217229e-3
GO:0060711 labyrinthine layer development 8.236531e-3
GO:0051382 kinetochore assembly 8.339304e-3
GO:0010700 negative regulation of norepinephrine secretion 8.395093e-3
GO:0043060 meiotic metaphase I plate congression 8.417001e-3
GO:0018393 internal peptidyl-lysine acetylation 8.469168e-3
GO:0002839 positive regulation of immune response to tumor cell 8.564835e-3
GO:0015669 gas transport 8.702777e-3
GO:0003407 neural retina development 8.830143e-3
GO:0010225 response to UV-C 8.874069e-3
GO:0034616 response to laminar fluid shear stress 8.972158e-3
GO:0045746 negative regulation of Notch signaling pathway 9.033177e-3
GO:0048593 camera-type eye morphogenesis 9.174008e-3
GO:0009637 response to blue light 9.223054e-3
GO:0021526 medial motor column neuron differentiation 9.284158e-3
GO:0008617 guanosine metabolic process 9.291346e-3
GO:0022900 electron transport chain 9.441861e-3
GO:0072331 signal transduction by p53 class mediator 9.632495e-3
GO:0090199 regulation of release of cytochrome c from mitochondria 9.680511e-3
GO:0018126 protein hydroxylation 9.713872e-3
GO:0043574 peroxisomal transport 9.926866e-3
GO:0003105 negative regulation of glomerular filtration 1.003072e-2
GO:2000104 negative regulation of DNA-dependent DNA replication 1.005189e-2
GO:0000244 assembly of spliceosomal tri-snRNP 1.007964e-2
GO:0032660 regulation of interleukin-17 production 1.010142e-2
GO:0070389 chaperone cofactor-dependent protein refolding 1.018234e-2
GO:0048554 positive regulation of metalloenzyme activity 1.030734e-2
GO:0045819 positive regulation of glycogen catabolic process 1.056164e-2
GO:0032594 protein transport within lipid bilayer 1.056282e-2
GO:0010800 positive regulation of peptidyl-threonine phosphorylation 1.058932e-2
GO:0043543 protein acylation 1.072990e-2
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 1.074477e-2
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 1.074477e-2
GO:0061302 smooth muscle cell-matrix adhesion 1.074477e-2
GO:0033483 gas homeostasis 1.087875e-2
GO:0090201 negative regulation of release of cytochrome c from mitochondria 1.098399e-2
GO:0000082 G1/S transition of mitotic cell cycle 1.127590e-2
GO:0060576 intestinal epithelial cell development 1.133267e-2
GO:0010002 cardioblast differentiation 1.144196e-2


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0090304 nucleic acid metabolic process 5.126838e-11
GO:0045653 negative regulation of megakaryocyte differentiation 5.198810e-11
GO:0010467 gene expression 3.231668e-10
GO:0048743 positive regulation of skeletal muscle fiber development 6.859343e-10
GO:0043001 Golgi to plasma membrane protein transport 3.734501e-9
GO:0015966 diadenosine tetraphosphate biosynthetic process 4.857078e-9
GO:0016070 RNA metabolic process 1.253623e-8
GO:0051028 mRNA transport 1.279973e-8
GO:0006139 nucleobase-containing compound metabolic process 2.052973e-8
GO:0006893 Golgi to plasma membrane transport 5.665356e-8
GO:0008612 peptidyl-lysine modification to hypusine 9.152360e-8
GO:0034227 tRNA thio-modification 1.017094e-7
GO:0044260 cellular macromolecule metabolic process 1.652809e-7
GO:0034337 RNA folding 1.857218e-7
GO:0006403 RNA localization 2.686574e-7
GO:0044029 hypomethylation of CpG island 5.387475e-7
GO:0002098 tRNA wobble uridine modification 7.912505e-7
GO:0034641 cellular nitrogen compound metabolic process 9.749608e-7
GO:0033617 mitochondrial respiratory chain complex IV assembly 1.153363e-6
GO:0048239 negative regulation of DNA recombination at telomere 1.153363e-6
GO:0006430 lysyl-tRNA aminoacylation 1.153363e-6
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 1.269130e-6
GO:0006892 post-Golgi vesicle-mediated transport 1.366587e-6
GO:0006651 diacylglycerol biosynthetic process 1.598232e-6
GO:0010631 epithelial cell migration 1.767288e-6
GO:0006306 DNA methylation 2.258096e-6
GO:0048193 Golgi vesicle transport 2.258626e-6
GO:2000279 negative regulation of DNA biosynthetic process 2.642127e-6
GO:0045905 positive regulation of translational termination 2.674782e-6
GO:0006452 translational frameshifting 2.674782e-6
GO:0045901 positive regulation of translational elongation 2.674782e-6
GO:0070078 histone H3-R2 demethylation 2.873655e-6
GO:0070079 histone H4-R3 demethylation 2.873655e-6
GO:0022417 protein maturation by protein folding 2.873655e-6
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 2.873655e-6
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 2.873655e-6
GO:0033591 response to L-ascorbic acid 3.063399e-6
GO:0045746 negative regulation of Notch signaling pathway 3.201229e-6
GO:0050658 RNA transport 3.266777e-6
GO:0010288 response to lead ion 5.574610e-6
GO:0001892 embryonic placenta development 6.513981e-6
GO:0006449 regulation of translational termination 8.420187e-6
GO:0034101 erythrocyte homeostasis 8.871155e-6
GO:0006807 nitrogen compound metabolic process 9.171446e-6
GO:2000278 regulation of DNA biosynthetic process 9.299690e-6
GO:0045652 regulation of megakaryocyte differentiation 1.223368e-5
GO:0044030 regulation of DNA methylation 1.288600e-5
GO:0048643 positive regulation of skeletal muscle tissue development 1.327712e-5
GO:0034728 nucleosome organization 1.570337e-5
GO:0006396 RNA processing 1.703314e-5
GO:0045585 positive regulation of cytotoxic T cell differentiation 1.961401e-5
GO:0032693 negative regulation of interleukin-10 production 1.998869e-5
GO:0016071 mRNA metabolic process 2.363188e-5
GO:0006397 mRNA processing 2.497744e-5
GO:0006334 nucleosome assembly 2.926139e-5
GO:0090130 tissue migration 3.115190e-5
GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway 3.201980e-5
GO:0019348 dolichol metabolic process 3.265081e-5
GO:0001832 blastocyst growth 3.273569e-5
GO:0015959 diadenosine polyphosphate metabolic process 3.290532e-5
GO:0030218 erythrocyte differentiation 3.471562e-5
GO:0002678 positive regulation of chronic inflammatory response 3.487782e-5
GO:0006448 regulation of translational elongation 3.944523e-5
GO:0000079 regulation of cyclin-dependent protein kinase activity 4.282613e-5
GO:0051131 chaperone-mediated protein complex assembly 4.378154e-5
GO:0006402 mRNA catabolic process 4.695266e-5
GO:0040019 positive regulation of embryonic development 4.708490e-5
GO:0018192 enzyme active site formation via L-cysteine persulfide 4.911621e-5
GO:0072355 histone H3-T3 phosphorylation 5.468101e-5
GO:0042703 menstruation 5.468101e-5
GO:0019101 female somatic sex determination 5.468101e-5
GO:0006259 DNA metabolic process 5.672984e-5
GO:0065004 protein-DNA complex assembly 5.918210e-5
GO:0000956 nuclear-transcribed mRNA catabolic process 6.474364e-5
GO:0046339 diacylglycerol metabolic process 6.506837e-5
GO:0016578 histone deubiquitination 6.689603e-5
GO:0009296 flagellum assembly 6.689603e-5
GO:0071103 DNA conformation change 6.974566e-5
GO:0006351 transcription, DNA-dependent 8.231168e-5
GO:0090138 regulation of actin cytoskeleton organization by cell-cell adhesion 8.423515e-5
GO:0051901 positive regulation of mitochondrial depolarization 8.618252e-5
GO:0032774 RNA biosynthetic process 9.750826e-5
GO:0009956 radial pattern formation 9.949842e-5
GO:0032205 negative regulation of telomere maintenance 1.105140e-4
GO:0045844 positive regulation of striated muscle tissue development 1.106350e-4
GO:0032274 gonadotropin secretion 1.111073e-4
GO:0051661 maintenance of centrosome location 1.164113e-4
GO:0090086 negative regulation of protein deubiquitination 1.218419e-4
GO:0006323 DNA packaging 1.338314e-4
GO:0008593 regulation of Notch signaling pathway 1.387233e-4
GO:0006507 GPI anchor release 1.425016e-4
GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process 1.425016e-4
GO:0006304 DNA modification 1.567227e-4
GO:0043064 flagellum organization 1.836844e-4
GO:0060711 labyrinthine layer development 2.126103e-4
GO:0048024 regulation of nuclear mRNA splicing, via spliceosome 2.215461e-4
GO:0034276 kynurenic acid biosynthetic process 2.396136e-4
GO:0019046 reactivation of latent virus 2.396136e-4
GO:0002534 cytokine production involved in inflammatory response 2.396136e-4
GO:0000027 ribosomal large subunit assembly 2.396136e-4
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 2.413211e-4
GO:0001913 T cell mediated cytotoxicity 2.505333e-4
GO:0071824 protein-DNA complex subunit organization 2.540401e-4
GO:0072498 embryonic skeletal joint development 2.727783e-4
GO:0043048 dolichyl monophosphate biosynthetic process 2.737419e-4
GO:0072334 UDP-galactose transmembrane transport 2.737419e-4
GO:0000244 assembly of spliceosomal tri-snRNP 2.737419e-4
GO:0031497 chromatin assembly 3.051971e-4
GO:0006626 protein targeting to mitochondrion 3.091032e-4
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 3.111116e-4
GO:0051155 positive regulation of striated muscle cell differentiation 3.112731e-4
GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway 3.162935e-4
GO:0043484 regulation of RNA splicing 3.182391e-4
GO:0035137 hindlimb morphogenesis 3.343712e-4
GO:0046929 negative regulation of neurotransmitter secretion 3.468844e-4
GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide 3.468844e-4
GO:0007288 sperm axoneme assembly 3.615072e-4
GO:0046626 regulation of insulin receptor signaling pathway 3.638489e-4
GO:0034645 cellular macromolecule biosynthetic process 3.649841e-4
GO:0016068 type I hypersensitivity 3.822474e-4
GO:0031057 negative regulation of histone modification 4.339762e-4
GO:0003310 pancreatic A cell differentiation 4.480112e-4
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 4.707702e-4
GO:0006888 ER to Golgi vesicle-mediated transport 4.870913e-4
GO:0000415 negative regulation of histone H3-K36 methylation 4.956382e-4
GO:0035269 protein O-linked mannosylation 4.956382e-4
GO:0031576 G2/M transition checkpoint 5.031056e-4
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 5.050660e-4
GO:0042694 muscle cell fate specification 5.050660e-4
GO:0032515 negative regulation of phosphoprotein phosphatase activity 5.131882e-4
GO:0060024 rhythmic synaptic transmission 5.131882e-4
GO:0090212 negative regulation of establishment of blood-brain barrier 5.302002e-4
GO:0015969 guanosine tetraphosphate metabolic process 5.302002e-4
GO:0002638 negative regulation of immunoglobulin production 5.302002e-4
GO:0001811 negative regulation of type I hypersensitivity 5.302002e-4
GO:0009059 macromolecule biosynthetic process 5.454806e-4
GO:0060272 embryonic skeletal joint morphogenesis 5.902485e-4
GO:0006401 RNA catabolic process 5.904242e-4
GO:0030101 natural killer cell activation 5.985654e-4
GO:0000722 telomere maintenance via recombination 6.201983e-4
GO:0043170 macromolecule metabolic process 6.267330e-4
GO:0008380 RNA splicing 6.441836e-4
GO:0006368 transcription elongation from RNA polymerase II promoter 6.616956e-4
GO:0006325 chromatin organization 6.655615e-4
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 6.851489e-4
GO:0090288 negative regulation of cellular response to growth factor stimulus 7.488748e-4
GO:0060710 chorio-allantoic fusion 7.585860e-4
GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment 7.846131e-4
GO:0051276 chromosome organization 8.179736e-4
GO:0030719 P granule organization 8.229217e-4
GO:0002763 positive regulation of myeloid leukocyte differentiation 8.726414e-4
GO:0034551 mitochondrial respiratory chain complex III assembly 9.539594e-4
GO:0018993 somatic sex determination 9.539594e-4
GO:0050886 endocrine process 9.958939e-4
GO:0070086 ubiquitin-dependent endocytosis 1.005719e-3
GO:0019858 cytosine metabolic process 1.005719e-3
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential 1.005719e-3
GO:0001966 thigmotaxis 1.005719e-3
GO:0007630 jump response 1.005719e-3
GO:0009637 response to blue light 1.005719e-3
GO:0034619 cellular chaperone-mediated protein complex assembly 1.006141e-3
GO:0021750 vestibular nucleus development 1.006141e-3
GO:0021590 cerebellum maturation 1.006141e-3
GO:0021679 cerebellar molecular layer development 1.006141e-3
GO:0060839 endothelial cell fate commitment 1.020159e-3
GO:0035082 axoneme assembly 1.020159e-3
GO:0072249 metanephric glomerular visceral epithelial cell development 1.041658e-3
GO:0048677 axon extension involved in regeneration 1.041658e-3
GO:0072274 metanephric glomerular basement membrane development 1.041658e-3
GO:0009443 pyridoxal 5'-phosphate salvage 1.041658e-3
GO:0045769 negative regulation of asymmetric cell division 1.041658e-3
GO:0035509 negative regulation of myosin-light-chain-phosphatase activity 1.041658e-3
GO:0043378 positive regulation of CD8-positive, alpha-beta T cell differentiation 1.041658e-3
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 1.063365e-3
GO:0009629 response to gravity 1.113777e-3
GO:0060850 regulation of transcription involved in cell fate commitment 1.129142e-3
GO:0060836 lymphatic endothelial cell differentiation 1.158464e-3
GO:0051568 histone H3-K4 methylation 1.226238e-3
GO:0033365 protein localization to organelle 1.227820e-3
GO:0051488 activation of anaphase-promoting complex activity 1.232517e-3
GO:0070668 positive regulation of mast cell proliferation 1.310994e-3
GO:0070171 negative regulation of tooth mineralization 1.310994e-3
GO:0018126 protein hydroxylation 1.355657e-3
GO:0072655 establishment of protein localization in mitochondrion 1.356301e-3
GO:0010225 response to UV-C 1.357621e-3
GO:0045862 positive regulation of proteolysis 1.397982e-3
GO:0060716 labyrinthine layer blood vessel development 1.435655e-3
GO:0040034 regulation of development, heterochronic 1.442007e-3
GO:0031577 spindle checkpoint 1.523731e-3
GO:0050684 regulation of mRNA processing 1.531061e-3
GO:0071353 cellular response to interleukin-4 1.631549e-3
GO:0032908 regulation of transforming growth factor beta1 production 1.631549e-3
GO:0002676 regulation of chronic inflammatory response 1.704541e-3
GO:0021897 forebrain astrocyte development 1.717166e-3
GO:0071247 cellular response to chromate 1.717166e-3
GO:0051149 positive regulation of muscle cell differentiation 1.837634e-3
GO:0050883 musculoskeletal movement, spinal reflex action 1.842493e-3
GO:0019058 viral infectious cycle 1.878550e-3
GO:0015931 nucleobase-containing compound transport 1.942073e-3
GO:0010569 regulation of double-strand break repair via homologous recombination 1.958976e-3
GO:0040032 post-embryonic body morphogenesis 1.998696e-3
GO:0031061 negative regulation of histone methylation 2.003027e-3
GO:0040029 regulation of gene expression, epigenetic 2.117668e-3
GO:0090085 regulation of protein deubiquitination 2.125307e-3
GO:0046591 embryonic leg joint morphogenesis 2.125307e-3
GO:0006108 malate metabolic process 2.218313e-3
GO:0072141 renal interstitial cell development 2.218499e-3
GO:0048384 retinoic acid receptor signaling pathway 2.225641e-3
GO:0001881 receptor recycling 2.255789e-3
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2.266245e-3
GO:0071173 spindle assembly checkpoint 2.281523e-3
GO:0071108 protein K48-linked deubiquitination 2.281523e-3
GO:0030099 myeloid cell differentiation 2.356264e-3
GO:0035094 response to nicotine 2.418261e-3
GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore 2.477793e-3
GO:0000966 RNA 5'-end processing 2.477793e-3
GO:0046079 dUMP catabolic process 2.477793e-3
GO:0006412 translation 2.496398e-3
GO:0034502 protein localization to chromosome 2.658138e-3
GO:0072259 metanephric interstitial cell development 2.715066e-3
GO:0090094 metanephric cap mesenchymal cell proliferation involved in metanephros development 2.715066e-3
GO:0072208 metanephric smooth muscle tissue development 2.715066e-3
GO:0072184 renal vesicle progenitor cell differentiation 2.715066e-3
GO:0072168 specification of anterior mesonephric tubule identity 2.715066e-3
GO:0072169 specification of posterior mesonephric tubule identity 2.715066e-3
GO:0010157 response to chlorate 2.747487e-3
GO:0000414 regulation of histone H3-K36 methylation 2.885796e-3
GO:0031848 protection from non-homologous end joining at telomere 2.885796e-3
GO:0072133 metanephric mesenchyme morphogenesis 2.885796e-3
GO:0021986 habenula development 2.885796e-3
GO:0051589 negative regulation of neurotransmitter transport 2.944325e-3
GO:0046031 ADP metabolic process 2.944325e-3
GO:0014051 gamma-aminobutyric acid secretion 2.944325e-3
GO:0042147 retrograde transport, endosome to Golgi 3.001402e-3
GO:0070585 protein localization in mitochondrion 3.105432e-3
GO:0006333 chromatin assembly or disassembly 3.142636e-3
GO:0070198 protein localization to chromosome, telomeric region 3.149224e-3
GO:0055119 relaxation of cardiac muscle 3.149224e-3
GO:0006354 transcription elongation, DNA-dependent 3.151977e-3
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 3.205086e-3
GO:0008535 respiratory chain complex IV assembly 3.329383e-3
GO:0000380 alternative nuclear mRNA splicing, via spliceosome 3.329383e-3
GO:0015780 nucleotide-sugar transport 3.426085e-3
GO:0046686 response to cadmium ion 3.430460e-3
GO:0018198 peptidyl-cysteine modification 3.525761e-3
GO:0030851 granulocyte differentiation 3.532639e-3
GO:0060986 endocrine hormone secretion 3.549548e-3
GO:0031657 regulation of cyclin-dependent protein kinase activity involved in G1/S 3.610662e-3
GO:0033119 negative regulation of RNA splicing 3.613394e-3
GO:0002438 acute inflammatory response to antigenic stimulus 3.613394e-3
GO:0065001 specification of axis polarity 3.638560e-3
GO:0043951 negative regulation of cAMP-mediated signaling 3.638560e-3
GO:0035093 spermatogenesis, exchange of chromosomal proteins 3.638560e-3
GO:0021524 visceral motor neuron differentiation 3.685757e-3
GO:0021578 hindbrain maturation 3.715722e-3
GO:0001835 blastocyst hatching 3.715722e-3
GO:2000112 regulation of cellular macromolecule biosynthetic process 3.752138e-3
GO:0060014 granulosa cell differentiation 3.863166e-3
GO:0070537 histone H2A K63-linked deubiquitination 3.863166e-3
GO:0006383 transcription from RNA polymerase III promoter 3.863166e-3
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 3.888544e-3
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 3.903056e-3
GO:0070189 kynurenine metabolic process 3.934447e-3
GO:0051865 protein autoubiquitination 3.947837e-3
GO:0007628 adult walking behavior 3.960382e-3
GO:0006473 protein acetylation 3.986272e-3
GO:0034154 toll-like receptor 7 signaling pathway 4.048106e-3
GO:0001834 trophectodermal cell proliferation 4.048106e-3
GO:0042415 norepinephrine metabolic process 4.056901e-3
GO:0000236 mitotic prometaphase 4.216461e-3
GO:0090321 positive regulation of chylomicron remnant clearance 4.216461e-3
GO:0090319 positive regulation of chylomicron remodeling 4.216461e-3
GO:0001890 placenta development 4.346567e-3
GO:0045040 protein import into mitochondrial outer membrane 4.357829e-3
GO:0035887 aortic smooth muscle cell differentiation 4.357829e-3
GO:0070536 protein K63-linked deubiquitination 4.371670e-3
GO:0000042 protein targeting to Golgi 4.380313e-3
GO:0045056 transcytosis 4.380313e-3
GO:0033160 positive regulation of protein import into nucleus, translocation 4.420356e-3
GO:0017004 cytochrome complex assembly 4.632365e-3
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 4.669454e-3
GO:0048505 regulation of timing of cell differentiation 4.697364e-3
GO:0071423 malate transmembrane transport 4.715973e-3
GO:0015709 thiosulfate transport 4.715973e-3
GO:0014005 microglia development 4.715973e-3
GO:0009159 deoxyribonucleoside monophosphate catabolic process 4.715973e-3
GO:0031572 G2/M transition DNA damage checkpoint 4.782045e-3
GO:0051252 regulation of RNA metabolic process 4.795612e-3
GO:0072183 negative regulation of nephron tubule epithelial cell differentiation 4.833090e-3
GO:0030237 female sex determination 4.833090e-3
GO:0000189 MAPK import into nucleus 4.833090e-3
GO:0051900 regulation of mitochondrial depolarization 4.874994e-3
GO:0018205 peptidyl-lysine modification 4.895728e-3
GO:0048625 myoblast cell fate commitment 5.017779e-3
GO:0060019 radial glial cell differentiation 5.044090e-3
GO:0051935 glutamate uptake involved in synaptic transmission 5.081887e-3
GO:0000281 cytokinesis after mitosis 5.081887e-3
GO:0043543 protein acylation 5.151289e-3
GO:0071174 mitotic cell cycle spindle checkpoint 5.162486e-3
GO:0030854 positive regulation of granulocyte differentiation 5.232116e-3
GO:0051053 negative regulation of DNA metabolic process 5.361638e-3
GO:0006044 N-acetylglucosamine metabolic process 5.369182e-3
GO:0050849 negative regulation of calcium-mediated signaling 5.567012e-3
GO:0051572 negative regulation of histone H3-K4 methylation 5.567012e-3
GO:0031060 regulation of histone methylation 5.647048e-3
GO:0015816 glycine transport 5.654442e-3
GO:0045494 photoreceptor cell maintenance 5.721886e-3
GO:0030522 intracellular receptor mediated signaling pathway 5.773337e-3
GO:0002262 myeloid cell homeostasis 5.800674e-3
GO:0001522 pseudouridine synthesis 5.896608e-3
GO:0001829 trophectodermal cell differentiation 6.006055e-3
GO:0021522 spinal cord motor neuron differentiation 6.041564e-3
GO:0006422 aspartyl-tRNA aminoacylation 6.212487e-3
GO:0046356 acetyl-CoA catabolic process 6.228668e-3
GO:0030223 neutrophil differentiation 6.357471e-3
GO:0070170 regulation of tooth mineralization 6.357471e-3
GO:0060713 labyrinthine layer morphogenesis 6.503036e-3
GO:0046007 negative regulation of activated T cell proliferation 6.509712e-3
GO:0000045 autophagic vacuole assembly 6.553292e-3
GO:0018193 peptidyl-amino acid modification 6.663553e-3
GO:0016584 nucleosome positioning 6.694174e-3
GO:0010458 exit from mitosis 6.694174e-3
GO:0034621 cellular macromolecular complex subunit organization 6.762683e-3
GO:0006172 ADP biosynthetic process 6.770256e-3
GO:0045089 positive regulation of innate immune response 6.940818e-3
GO:0032204 regulation of telomere maintenance 7.286323e-3
GO:0019067 viral assembly, maturation, egress, and release 7.286323e-3
GO:0048066 developmental pigmentation 7.520888e-3
GO:0014056 regulation of acetylcholine secretion 7.811015e-3
GO:0018243 protein O-linked glycosylation via threonine 7.846318e-3
GO:0018242 protein O-linked glycosylation via serine 7.846318e-3
GO:0019408 dolichol biosynthetic process 7.855303e-3
GO:2000299 negative regulation of Rho-dependent protein serine/threonine kinase activity 7.855303e-3
GO:0032853 positive regulation of Ran GTPase activity 7.855303e-3
GO:0015887 pantothenate transmembrane transport 7.855303e-3
GO:0015878 biotin transport 7.855303e-3
GO:0000115 regulation of transcription involved in S phase of mitotic cell cycle 7.855303e-3
GO:0006427 histidyl-tRNA aminoacylation 7.855303e-3
GO:0009786 regulation of asymmetric cell division 7.855303e-3
GO:0060376 positive regulation of mast cell differentiation 7.898993e-3
GO:0072553 terminal button organization 7.898993e-3
GO:0018095 protein polyglutamylation 7.898993e-3
GO:0042360 vitamin E metabolic process 7.898993e-3
GO:0009109 coenzyme catabolic process 7.953047e-3
GO:0032911 negative regulation of transforming growth factor beta1 production 7.965520e-3
GO:0060333 interferon-gamma-mediated signaling pathway 8.151124e-3
GO:0021918 regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment 8.151124e-3
GO:0003322 pancreatic A cell development 8.151124e-3
GO:0021905 forebrain-midbrain boundary formation 8.151124e-3
GO:0021902 commitment of neuronal cell to specific neuron type in forebrain 8.151124e-3
GO:0072594 establishment of protein localization to organelle 8.179716e-3
GO:0016572 histone phosphorylation 8.197770e-3
GO:0014002 astrocyte development 8.253464e-3
GO:0034660 ncRNA metabolic process 8.269155e-3
GO:0048821 erythrocyte development 8.359343e-3
GO:0045840 positive regulation of mitosis 8.572635e-3
GO:0001833 inner cell mass cell proliferation 8.642950e-3
GO:0051386 regulation of nerve growth factor receptor signaling pathway 8.746761e-3
GO:0030031 cell projection assembly 8.845723e-3
GO:0000413 protein peptidyl-prolyl isomerization 8.880063e-3
GO:0051457 maintenance of protein location in nucleus 8.920305e-3
GO:0060282 positive regulation of oocyte development 8.928508e-3
GO:0060281 regulation of oocyte development 8.928508e-3
GO:0000723 telomere maintenance 9.210463e-3
GO:0035195 gene silencing by miRNA 9.554659e-3
GO:0021520 spinal cord motor neuron cell fate specification 9.613500e-3
GO:0000301 retrograde transport, vesicle recycling within Golgi 9.613500e-3
GO:0006119 oxidative phosphorylation 9.613500e-3
GO:0090084 negative regulation of inclusion body assembly 9.723077e-3
GO:0008334 histone mRNA metabolic process 1.001340e-2
GO:0043923 positive regulation by host of viral transcription 1.001340e-2
GO:0061136 regulation of proteasomal protein catabolic process 1.013444e-2
GO:0046671 negative regulation of retinal cell programmed cell death 1.031133e-2
GO:0006283 transcription-coupled nucleotide-excision repair 1.031133e-2
GO:0006355 regulation of transcription, DNA-dependent 1.041191e-2
GO:0046755 non-lytic virus budding 1.049668e-2
GO:0071673 positive regulation of smooth muscle cell chemotaxis 1.049668e-2
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 1.049668e-2
GO:0043393 regulation of protein binding 1.065642e-2
GO:0016570 histone modification 1.068843e-2
GO:0051574 positive regulation of histone H3-K9 methylation 1.077624e-2
GO:0042773 ATP synthesis coupled electron transport 1.080591e-2
GO:0006620 posttranslational protein targeting to membrane 1.080591e-2
GO:0021548 pons development 1.087627e-2
GO:0006099 tricarboxylic acid cycle 1.114157e-2
GO:0034067 protein localization in Golgi apparatus 1.142729e-2
GO:0021523 somatic motor neuron differentiation 1.142729e-2
GO:0010107 potassium ion import 1.149924e-2
GO:0055118 negative regulation of cardiac muscle contraction 1.151528e-2
GO:0051895 negative regulation of focal adhesion assembly 1.151528e-2
GO:0072148 epithelial cell fate commitment 1.179573e-2
GO:0035886 vascular smooth muscle cell differentiation 1.189903e-2
GO:0014040 positive regulation of Schwann cell differentiation 1.196201e-2
GO:0051461 positive regulation of corticotropin secretion 1.196201e-2
GO:0048936 peripheral nervous system neuron axonogenesis 1.196505e-2
GO:0045818 negative regulation of glycogen catabolic process 1.196505e-2
GO:0051036 regulation of endosome size 1.196505e-2
GO:0001987 vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure 1.196505e-2
GO:0032543 mitochondrial translation 1.196505e-2
GO:0015761 mannose transport 1.196505e-2
GO:0046627 negative regulation of insulin receptor signaling pathway 1.197497e-2
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 1.198302e-2
GO:0042335 cuticle development 1.210190e-2
GO:0034470 ncRNA processing 1.233009e-2
GO:0006493 protein O-linked glycosylation 1.241493e-2
GO:0048704 embryonic skeletal system morphogenesis 1.242618e-2
GO:2000467 positive regulation of glycogen (starch) synthase activity 1.251218e-2
GO:0072595 maintenance of protein localization to organelle 1.251558e-2
GO:0050434 positive regulation of viral transcription 1.278396e-2
GO:0031102 neuron projection regeneration 1.279914e-2
GO:0019400 alditol metabolic process 1.315746e-2
GO:0001709 cell fate determination 1.327178e-2
GO:0060674 placenta blood vessel development 1.327290e-2
GO:0010224 response to UV-B 1.328406e-2
GO:0032516 positive regulation of phosphoprotein phosphatase activity 1.335036e-2
GO:0034622 cellular macromolecular complex assembly 1.336514e-2
GO:0071895 odontoblast differentiation 1.340804e-2
GO:0016090 prenol metabolic process 1.340804e-2
GO:0043654 recognition of apoptotic cell 1.340804e-2
GO:0044265 cellular macromolecule catabolic process 1.348681e-2
GO:0007403 glial cell fate determination 1.349230e-2
GO:0046544 development of secondary male sexual characteristics 1.349230e-2
GO:0051013 microtubule severing 1.349230e-2
GO:0034214 protein hexamerization 1.349230e-2
GO:0072203 cell proliferation involved in metanephros development 1.353796e-2
GO:0009179 purine ribonucleoside diphosphate metabolic process 1.353796e-2
GO:0030825 positive regulation of cGMP metabolic process 1.353796e-2
GO:0010722 regulation of ferrochelatase activity 1.358823e-2
GO:0042699 follicle-stimulating hormone signaling pathway 1.360945e-2
GO:0021517 ventral spinal cord development 1.365052e-2
GO:0001578 microtubule bundle formation 1.409569e-2
GO:0046069 cGMP catabolic process 1.420393e-2
GO:0060045 positive regulation of cardiac muscle cell proliferation 1.431624e-2
GO:0043414 macromolecule methylation 1.432039e-2
GO:0048706 embryonic skeletal system development 1.444346e-2
GO:0021997 neural plate axis specification 1.448318e-2
GO:0010834 telomere maintenance via telomere shortening 1.448318e-2
GO:0046628 positive regulation of insulin receptor signaling pathway 1.458544e-2
GO:0055075 potassium ion homeostasis 1.461525e-2
GO:0007094 mitotic cell cycle spindle assembly checkpoint 1.461525e-2
GO:0016568 chromatin modification 1.469336e-2
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 1.469360e-2
GO:0042271 susceptibility to natural killer cell mediated cytotoxicity 1.469360e-2
GO:0002524 hypersensitivity 1.488942e-2
GO:0032648 regulation of interferon-beta production 1.506134e-2
GO:0015812 gamma-aminobutyric acid transport 1.549866e-2
GO:0032859 activation of Ral GTPase activity 1.551419e-2
GO:0010468 regulation of gene expression 1.585030e-2
GO:2000779 regulation of double-strand break repair 1.593332e-2
GO:0015074 DNA integration 1.602763e-2
GO:0010556 regulation of macromolecule biosynthetic process 1.609490e-2
GO:0071480 cellular response to gamma radiation 1.613500e-2
GO:0071360 cellular response to exogenous dsRNA 1.613500e-2
GO:0030644 cellular chloride ion homeostasis 1.613500e-2
GO:0016540 protein autoprocessing 1.637391e-2
GO:0016569 covalent chromatin modification 1.644743e-2
GO:0006364 rRNA processing 1.649384e-2
GO:0032200 telomere organization 1.668710e-2
GO:0046006 regulation of activated T cell proliferation 1.676026e-2
GO:0031062 positive regulation of histone methylation 1.687989e-2
GO:0006612 protein targeting to membrane 1.699826e-2
GO:0070885 negative regulation of calcineurin-NFAT signaling pathway 1.708900e-2
GO:0010045 response to nickel ion 1.708900e-2
GO:0070625 zymogen granule exocytosis 1.708900e-2
GO:0035459 cargo loading into vesicle 1.708900e-2
GO:0016598 protein arginylation 1.708900e-2
GO:0032226 positive regulation of synaptic transmission, dopaminergic 1.720181e-2
GO:0006059 hexitol metabolic process 1.720181e-2
GO:2000286 receptor internalization involved in canonical Wnt receptor signaling pathway 1.733702e-2
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 1.733702e-2
GO:0006561 proline biosynthetic process 1.733702e-2
GO:0042552 myelination 1.737496e-2
GO:0032912 negative regulation of transforming growth factor beta2 production 1.760066e-2
GO:0035110 leg morphogenesis 1.767853e-2
GO:0008366 axon ensheathment 1.791331e-2
GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 1.817709e-2
GO:0019673 GDP-mannose metabolic process 1.817709e-2
GO:0018200 peptidyl-glutamic acid modification 1.820802e-2
GO:0048570 notochord morphogenesis 1.828006e-2
GO:0090083 regulation of inclusion body assembly 1.828006e-2
GO:0021545 cranial nerve development 1.833411e-2
GO:0021778 oligodendrocyte cell fate specification 1.835090e-2
GO:0006366 transcription from RNA polymerase II promoter 1.837179e-2
GO:0035067 negative regulation of histone acetylation 1.863229e-2
GO:0021535 cell migration in hindbrain 1.869793e-2
GO:0048872 homeostasis of number of cells 1.885634e-2
GO:0001937 negative regulation of endothelial cell proliferation 1.904191e-2
GO:0070647 protein modification by small protein conjugation or removal 1.915683e-2
GO:0070972 protein localization in endoplasmic reticulum 1.974790e-2
GO:0006353 transcription termination, DNA-dependent 1.987688e-2
GO:0071635 negative regulation of transforming growth factor beta production 1.991487e-2
GO:0035116 embryonic hindlimb morphogenesis 2.017665e-2
GO:0045943 positive regulation of transcription from RNA polymerase I promoter 2.033977e-2
GO:0070166 enamel mineralization 2.053935e-2
GO:0006312 mitotic recombination 2.053935e-2
GO:0070925 organelle assembly 2.062974e-2
GO:0055021 regulation of cardiac muscle tissue growth 2.082271e-2
GO:0060043 regulation of cardiac muscle cell proliferation 2.087725e-2
GO:0021796 cerebral cortex regionalization 2.089114e-2
GO:0000387 spliceosomal snRNP assembly 2.089114e-2