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Novel motif:9

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name:motif9_ANGGCT

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0071260 cellular response to mechanical stimulus 1.951895e-12
GO:0002238 response to molecule of fungal origin 9.592658e-12
GO:0006982 response to lipid hydroperoxide 1.146402e-11
GO:0033233 regulation of protein sumoylation 1.087222e-10
GO:0035814 negative regulation of renal sodium excretion 3.137232e-10
GO:0046626 regulation of insulin receptor signaling pathway 2.403387e-9
GO:0071732 cellular response to nitric oxide 3.195608e-9
GO:0045940 positive regulation of steroid metabolic process 3.832776e-9
GO:0008078 mesodermal cell migration 3.860046e-9
GO:0046627 negative regulation of insulin receptor signaling pathway 3.860222e-9
GO:0033599 regulation of mammary gland epithelial cell proliferation 1.540440e-8
GO:0019884 antigen processing and presentation of exogenous antigen 1.683091e-8
GO:0042074 cell migration involved in gastrulation 2.862108e-8
GO:0050995 negative regulation of lipid catabolic process 3.121014e-8
GO:0035307 positive regulation of protein dephosphorylation 3.202685e-8
GO:0046473 phosphatidic acid metabolic process 4.682349e-8
GO:0031424 keratinization 4.682738e-8
GO:0007509 mesoderm migration involved in gastrulation 4.899533e-8
GO:0045628 regulation of T-helper 2 cell differentiation 5.848793e-8
GO:0033235 positive regulation of protein sumoylation 6.301616e-8
GO:0010832 negative regulation of myotube differentiation 6.934358e-8
GO:0009612 response to mechanical stimulus 7.770410e-8
GO:0006544 glycine metabolic process 9.624584e-8
GO:0014898 cardiac muscle hypertrophy in response to stress 1.074597e-7
GO:0071496 cellular response to external stimulus 1.207446e-7
GO:0071214 cellular response to abiotic stimulus 1.231659e-7
GO:0035306 positive regulation of dephosphorylation 1.247739e-7
GO:0014874 response to stimulus involved in regulation of muscle adaptation 1.304818e-7
GO:0048771 tissue remodeling 1.515505e-7
GO:0042744 hydrogen peroxide catabolic process 1.563216e-7
GO:0002439 chronic inflammatory response to antigenic stimulus 1.597696e-7
GO:0002437 inflammatory response to antigenic stimulus 2.742831e-7
GO:0021526 medial motor column neuron differentiation 3.243118e-7
GO:0009895 negative regulation of catabolic process 3.991848e-7
GO:0060708 spongiotrophoblast differentiation 4.260612e-7
GO:0034333 adherens junction assembly 4.310042e-7
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion 4.369791e-7
GO:0002703 regulation of leukocyte mediated immunity 4.461929e-7
GO:0001885 endothelial cell development 4.953422e-7
GO:0051154 negative regulation of striated muscle cell differentiation 6.028052e-7
GO:0034616 response to laminar fluid shear stress 6.402527e-7
GO:0002513 tolerance induction to self antigen 6.411870e-7
GO:0045576 mast cell activation 7.021085e-7
GO:0006884 cell volume homeostasis 7.915334e-7
GO:0014888 striated muscle adaptation 8.356913e-7
GO:0070327 thyroid hormone transport 8.379059e-7
GO:0060349 bone morphogenesis 8.783262e-7
GO:0002274 myeloid leukocyte activation 9.989604e-7
GO:0035304 regulation of protein dephosphorylation 9.999691e-7
GO:0009069 serine family amino acid metabolic process 1.014835e-6
GO:0061028 establishment of endothelial barrier 1.057802e-6
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1.125250e-6
GO:0072109 glomerular mesangium development 1.158313e-6
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter 1.219030e-6
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 1.499006e-6
GO:0060620 regulation of cholesterol import 1.640952e-6
GO:0051591 response to cAMP 1.643629e-6
GO:0071731 response to nitric oxide 1.680757e-6
GO:0032720 negative regulation of tumor necrosis factor production 1.841573e-6
GO:0045623 negative regulation of T-helper cell differentiation 1.843821e-6
GO:0033601 positive regulation of mammary gland epithelial cell proliferation 1.995953e-6
GO:0051044 positive regulation of membrane protein ectodomain proteolysis 2.017769e-6
GO:0045833 negative regulation of lipid metabolic process 2.238527e-6
GO:0003158 endothelium development 2.409502e-6
GO:0002708 positive regulation of lymphocyte mediated immunity 2.493608e-6
GO:0002711 positive regulation of T cell mediated immunity 2.663504e-6
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 2.702021e-6
GO:0050902 leukocyte adhesive activation 2.702021e-6
GO:0050779 RNA destabilization 2.722927e-6
GO:0070670 response to interleukin-4 2.728708e-6
GO:0045581 negative regulation of T cell differentiation 2.752363e-6
GO:0007096 regulation of exit from mitosis 2.864352e-6
GO:0003009 skeletal muscle contraction 2.895947e-6
GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 2.973329e-6
GO:0045065 cytotoxic T cell differentiation 2.999807e-6
GO:0070849 response to epidermal growth factor stimulus 3.001617e-6
GO:0006545 glycine biosynthetic process 3.129096e-6
GO:0045638 negative regulation of myeloid cell differentiation 3.182338e-6
GO:0010987 negative regulation of high-density lipoprotein particle clearance 3.232004e-6
GO:0010897 negative regulation of triglyceride catabolic process 3.232004e-6
GO:0010893 positive regulation of steroid biosynthetic process 3.269852e-6
GO:0014050 negative regulation of glutamate secretion 3.366461e-6
GO:0006654 phosphatidic acid biosynthetic process 3.414845e-6
GO:0033044 regulation of chromosome organization 4.406649e-6
GO:0000720 pyrimidine dimer repair by nucleotide-excision repair 4.801393e-6
GO:0070555 response to interleukin-1 5.477348e-6
GO:0006694 steroid biosynthetic process 5.502602e-6
GO:0043471 regulation of cellular carbohydrate catabolic process 5.786576e-6
GO:0060033 anatomical structure regression 6.260370e-6
GO:0030204 chondroitin sulfate metabolic process 6.315676e-6
GO:0045647 negative regulation of erythrocyte differentiation 6.427873e-6
GO:0046724 oxalic acid secretion 7.032894e-6
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate 7.032894e-6
GO:0034116 positive regulation of heterotypic cell-cell adhesion 7.122146e-6
GO:0046639 negative regulation of alpha-beta T cell differentiation 7.280223e-6
GO:0070071 proton-transporting two-sector ATPase complex assembly 7.421569e-6
GO:0002449 lymphocyte mediated immunity 7.532550e-6
GO:0050727 regulation of inflammatory response 7.604334e-6
GO:0045908 negative regulation of vasodilation 7.751028e-6
GO:0031064 negative regulation of histone deacetylation 7.850329e-6
GO:0072110 glomerular mesangial cell proliferation 7.888420e-6
GO:0002443 leukocyte mediated immunity 8.321196e-6
GO:0048630 skeletal muscle tissue growth 8.921694e-6
GO:0032204 regulation of telomere maintenance 9.912566e-6
GO:0045630 positive regulation of T-helper 2 cell differentiation 1.079163e-5
GO:0015695 organic cation transport 1.096787e-5
GO:0002719 negative regulation of cytokine production involved in immune response 1.098202e-5
GO:0019048 virus-host interaction 1.105763e-5
GO:0001766 membrane raft polarization 1.140341e-5
GO:0043503 skeletal muscle fiber adaptation 1.142194e-5
GO:0060621 negative regulation of cholesterol import 1.169165e-5
GO:0046006 regulation of activated T cell proliferation 1.171571e-5
GO:0043500 muscle adaptation 1.218089e-5
GO:0045622 regulation of T-helper cell differentiation 1.244668e-5
GO:0070301 cellular response to hydrogen peroxide 1.394450e-5
GO:0006685 sphingomyelin catabolic process 1.401288e-5
GO:0043249 erythrocyte maturation 1.436241e-5
GO:0060712 spongiotrophoblast layer development 1.443127e-5
GO:0042108 positive regulation of cytokine biosynthetic process 1.547913e-5
GO:0045820 negative regulation of glycolysis 1.601555e-5
GO:0009650 UV protection 1.629307e-5
GO:0033129 positive regulation of histone phosphorylation 1.637523e-5
GO:0071347 cellular response to interleukin-1 1.651271e-5
GO:0030206 chondroitin sulfate biosynthetic process 1.726104e-5
GO:0042482 positive regulation of odontogenesis 1.767629e-5
GO:0042512 negative regulation of tyrosine phosphorylation of Stat1 protein 1.778826e-5
GO:0002706 regulation of lymphocyte mediated immunity 1.780575e-5
GO:0005981 regulation of glycogen catabolic process 1.800335e-5
GO:0030593 neutrophil chemotaxis 1.816096e-5
GO:0032729 positive regulation of interferon-gamma production 1.865767e-5
GO:0051043 regulation of membrane protein ectodomain proteolysis 1.913503e-5
GO:0032526 response to retinoic acid 2.021905e-5
GO:0003300 cardiac muscle hypertrophy 2.086096e-5
GO:0016311 dephosphorylation 2.124572e-5
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 2.298084e-5
GO:0009817 defense response to fungus, incompatible interaction 2.298084e-5
GO:0032753 positive regulation of interleukin-4 production 2.415402e-5
GO:0046543 development of secondary female sexual characteristics 2.427448e-5
GO:0051532 regulation of NFAT protein import into nucleus 2.453264e-5
GO:0032981 mitochondrial respiratory chain complex I assembly 2.486853e-5
GO:0042104 positive regulation of activated T cell proliferation 2.579318e-5
GO:0010829 negative regulation of glucose transport 2.581050e-5
GO:0010830 regulation of myotube differentiation 2.588162e-5
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 2.639733e-5
GO:0051168 nuclear export 2.756707e-5
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 2.822040e-5
GO:0045076 regulation of interleukin-2 biosynthetic process 2.929580e-5
GO:0051896 regulation of protein kinase B signaling cascade 2.992384e-5
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 3.012804e-5
GO:0032649 regulation of interferon-gamma production 3.146956e-5
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 3.275958e-5
GO:0072126 positive regulation of glomerular mesangial cell proliferation 3.395979e-5
GO:0071506 cellular response to mycophenolic acid 3.395979e-5
GO:0006417 regulation of translation 3.421898e-5
GO:0010872 regulation of cholesterol esterification 3.665033e-5
GO:0031330 negative regulation of cellular catabolic process 3.679309e-5
GO:0033189 response to vitamin A 3.902214e-5
GO:0016126 sterol biosynthetic process 3.919021e-5
GO:0033108 mitochondrial respiratory chain complex assembly 4.031838e-5
GO:0031440 regulation of mRNA 3'-end processing 4.068224e-5
GO:0045590 negative regulation of regulatory T cell differentiation 4.093079e-5
GO:0030388 fructose 1,6-bisphosphate metabolic process 4.093151e-5
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 4.098945e-5
GO:0014894 response to denervation involved in regulation of muscle adaptation 4.129076e-5
GO:0002089 lens morphogenesis in camera-type eye 4.144432e-5
GO:0045176 apical protein localization 4.209741e-5
GO:0002699 positive regulation of immune effector process 4.247489e-5
GO:0046849 bone remodeling 4.257849e-5
GO:0001817 regulation of cytokine production 4.326122e-5
GO:0042117 monocyte activation 4.334391e-5
GO:0045446 endothelial cell differentiation 4.372980e-5
GO:0019087 transformation of host cell by virus 4.413305e-5
GO:0090130 tissue migration 4.542571e-5
GO:0052509 positive regulation by symbiont of host defense response 4.664984e-5
GO:0044341 sodium-dependent phosphate transport 4.911549e-5
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 5.028418e-5
GO:0043029 T cell homeostasis 5.431272e-5
GO:0030853 negative regulation of granulocyte differentiation 5.507458e-5
GO:0008624 induction of apoptosis by extracellular signals 5.549205e-5
GO:0006684 sphingomyelin metabolic process 5.736961e-5
GO:0042797 tRNA transcription from RNA polymerase III promoter 5.819338e-5
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter 5.819338e-5
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 5.876526e-5
GO:0043094 cellular metabolic compound salvage 5.966923e-5
GO:0045061 thymic T cell selection 6.225512e-5
GO:0002478 antigen processing and presentation of exogenous peptide antigen 6.389234e-5
GO:0043932 ossification involved in bone remodeling 6.410347e-5
GO:0010529 negative regulation of transposition 6.482062e-5
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6.612315e-5
GO:0051781 positive regulation of cell division 6.794227e-5
GO:0050830 defense response to Gram-positive bacterium 6.800591e-5
GO:0045626 negative regulation of T-helper 1 cell differentiation 6.870931e-5
GO:0002740 negative regulation of cytokine secretion involved in immune response 6.965689e-5
GO:0006107 oxaloacetate metabolic process 7.097836e-5
GO:0034340 response to type I interferon 7.102702e-5
GO:0032581 ER-dependent peroxisome organization 7.201417e-5
GO:0010799 regulation of peptidyl-threonine phosphorylation 7.203637e-5
GO:0030865 cortical cytoskeleton organization 7.549804e-5
GO:0006348 chromatin silencing at telomere 7.598519e-5
GO:0002889 regulation of immunoglobulin mediated immune response 7.703725e-5
GO:0046730 induction of host immune response by virus 7.729177e-5
GO:0023021 termination of signal transduction 7.981730e-5
GO:0010624 regulation of Schwann cell proliferation 8.121365e-5
GO:0045651 positive regulation of macrophage differentiation 8.124467e-5
GO:0031063 regulation of histone deacetylation 8.130398e-5
GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 8.244363e-5
GO:0032689 negative regulation of interferon-gamma production 8.455674e-5
GO:0033590 response to cobalamin 8.475524e-5
GO:0006117 acetaldehyde metabolic process 8.475524e-5
GO:0050654 chondroitin sulfate proteoglycan metabolic process 8.565601e-5
GO:0043415 positive regulation of skeletal muscle tissue regeneration 8.800026e-5
GO:0042137 sequestering of neurotransmitter 8.976293e-5
GO:0010742 macrophage derived foam cell differentiation 8.992103e-5
GO:0010873 positive regulation of cholesterol esterification 9.069580e-5
GO:0006700 C21-steroid hormone biosynthetic process 9.453666e-5
GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 9.681422e-5
GO:0016973 poly(A)+ mRNA export from nucleus 9.831413e-5
GO:0010939 regulation of necrotic cell death 9.990507e-5
GO:0042335 cuticle development 1.009266e-4
GO:0009070 serine family amino acid biosynthetic process 1.031502e-4
GO:0006290 pyrimidine dimer repair 1.082372e-4
GO:0060707 trophoblast giant cell differentiation 1.094137e-4
GO:0060337 type I interferon-mediated signaling pathway 1.096264e-4
GO:0051302 regulation of cell division 1.112743e-4
GO:0042304 regulation of fatty acid biosynthetic process 1.115495e-4
GO:0009303 rRNA transcription 1.127682e-4
GO:0010626 negative regulation of Schwann cell proliferation 1.172027e-4
GO:0032365 intracellular lipid transport 1.204648e-4
GO:0071356 cellular response to tumor necrosis factor 1.231779e-4
GO:0014805 smooth muscle adaptation 1.234089e-4
GO:0035066 positive regulation of histone acetylation 1.235869e-4
GO:0033326 cerebrospinal fluid secretion 1.236901e-4
GO:0046827 positive regulation of protein export from nucleus 1.239657e-4
GO:0031442 positive regulation of mRNA 3'-end processing 1.244807e-4
GO:0019532 oxalate transport 1.246849e-4
GO:0010940 positive regulation of necrotic cell death 1.271322e-4
GO:0007253 cytoplasmic sequestering of NF-kappaB 1.281573e-4
GO:0051665 membrane raft localization 1.348045e-4
GO:0006942 regulation of striated muscle contraction 1.356660e-4
GO:0046134 pyrimidine nucleoside biosynthetic process 1.358473e-4
GO:0051534 negative regulation of NFAT protein import into nucleus 1.383297e-4
GO:0060644 mammary gland epithelial cell differentiation 1.439860e-4
GO:0045637 regulation of myeloid cell differentiation 1.441877e-4
GO:0045066 regulatory T cell differentiation 1.445865e-4
GO:0042542 response to hydrogen peroxide 1.449157e-4
GO:0032355 response to estradiol stimulus 1.483375e-4
GO:0002712 regulation of B cell mediated immunity 1.499054e-4
GO:0018012 N-terminal peptidyl-alanine trimethylation 1.500828e-4
GO:0035572 N-terminal peptidyl-serine dimethylation 1.500828e-4
GO:0035573 N-terminal peptidyl-serine trimethylation 1.500828e-4
GO:0018016 N-terminal peptidyl-proline dimethylation 1.500828e-4
GO:0060262 negative regulation of N-terminal protein palmitoylation 1.560963e-4
GO:0045980 negative regulation of nucleotide metabolic process 1.626824e-4
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 1.674716e-4
GO:0043585 nose morphogenesis 1.731105e-4
GO:0006927 transformed cell apoptosis 1.731105e-4
GO:0046108 uridine metabolic process 1.732972e-4
GO:0042742 defense response to bacterium 1.788781e-4
GO:0060178 regulation of exocyst localization 1.820037e-4
GO:0001928 regulation of exocyst assembly 1.820037e-4
GO:0033273 response to vitamin 1.848102e-4
GO:0050776 regulation of immune response 1.861018e-4
GO:0060348 bone development 1.874037e-4
GO:0006695 cholesterol biosynthetic process 1.958025e-4
GO:0030225 macrophage differentiation 1.962234e-4
GO:0015693 magnesium ion transport 1.993553e-4
GO:0045922 negative regulation of fatty acid metabolic process 2.012793e-4
GO:0071460 cellular response to cell-matrix adhesion 2.016720e-4
GO:0070587 regulation of cell-cell adhesion involved in gastrulation 2.019031e-4
GO:0034114 regulation of heterotypic cell-cell adhesion 2.019031e-4
GO:0052200 response to host defenses 2.042723e-4
GO:0006521 regulation of cellular amino acid metabolic process 2.165215e-4
GO:0060754 positive regulation of mast cell chemotaxis 2.170527e-4
GO:0015850 organic alcohol transport 2.173183e-4
GO:0006909 phagocytosis 2.173435e-4
GO:0017148 negative regulation of translation 2.178568e-4
GO:0006471 protein ADP-ribosylation 2.283586e-4
GO:0033238 regulation of cellular amine metabolic process 2.350341e-4
GO:0033159 negative regulation of protein import into nucleus, translocation 2.352943e-4
GO:0048144 fibroblast proliferation 2.352943e-4
GO:0070164 negative regulation of adiponectin secretion 2.417429e-4
GO:0060355 positive regulation of cell adhesion molecule production 2.417429e-4
GO:0035505 positive regulation of myosin light chain kinase activity 2.417429e-4
GO:0051897 positive regulation of protein kinase B signaling cascade 2.418197e-4
GO:0060744 mammary gland branching involved in thelarche 2.419002e-4
GO:0009395 phospholipid catabolic process 2.456341e-4
GO:0033194 response to hydroperoxide 2.456872e-4
GO:0071803 positive regulation of podosome assembly 2.520145e-4
GO:0003108 negative regulation of the force of heart contraction by chemical signal 2.520145e-4
GO:0090305 nucleic acid phosphodiester bond hydrolysis 2.530646e-4
GO:0045084 positive regulation of interleukin-12 biosynthetic process 2.564720e-4
GO:0021773 striatal medium spiny neuron differentiation 2.566427e-4
GO:0045589 regulation of regulatory T cell differentiation 2.566427e-4
GO:0035065 regulation of histone acetylation 2.598774e-4
GO:0000244 assembly of spliceosomal tri-snRNP 2.610942e-4
GO:0070669 response to interleukin-2 2.682121e-4
GO:0006449 regulation of translational termination 2.683954e-4
GO:0002718 regulation of cytokine production involved in immune response 2.748235e-4
GO:0006188 IMP biosynthetic process 2.842449e-4
GO:0030866 cortical actin cytoskeleton organization 2.873024e-4
GO:0009620 response to fungus 2.952110e-4
GO:0060391 positive regulation of SMAD protein import into nucleus 2.978060e-4
GO:0031297 replication fork processing 2.989875e-4
GO:0042035 regulation of cytokine biosynthetic process 2.995250e-4
GO:0045556 positive regulation of TRAIL biosynthetic process 2.997641e-4
GO:0015874 norepinephrine transport 2.997641e-4
GO:0002698 negative regulation of immune effector process 2.999066e-4
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity 3.037041e-4
GO:0046732 active induction of host immune response by virus 3.037766e-4
GO:0002250 adaptive immune response 3.052967e-4
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 3.126109e-4
GO:0000387 spliceosomal snRNP assembly 3.162628e-4
GO:0070307 lens fiber cell development 3.170462e-4
GO:0051937 catecholamine transport 3.272106e-4
GO:0022010 central nervous system myelination 3.306742e-4
GO:0036006 cellular response to macrophage colony-stimulating factor stimulus 3.321970e-4
GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly 3.462878e-4
GO:0032715 negative regulation of interleukin-6 production 3.493796e-4
GO:0035229 positive regulation of glutamate-cysteine ligase activity 3.495398e-4
GO:0006611 protein export from nucleus 3.590169e-4
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion 3.609892e-4
GO:0043574 peroxisomal transport 3.642471e-4
GO:0010523 negative regulation of calcium ion transport into cytosol 3.689813e-4
GO:0006405 RNA export from nucleus 3.732347e-4
GO:0048813 dendrite morphogenesis 3.746407e-4
GO:0002821 positive regulation of adaptive immune response 3.851737e-4
GO:0034329 cell junction assembly 3.903022e-4
GO:0043304 regulation of mast cell degranulation 3.931554e-4
GO:0006853 carnitine shuttle 3.938945e-4
GO:0045073 regulation of chemokine biosynthetic process 4.182717e-4
GO:0051384 response to glucocorticoid stimulus 4.292715e-4
GO:0097107 postsynaptic density assembly 4.306134e-4
GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 4.306134e-4
GO:0071104 response to interleukin-9 4.306134e-4
GO:0003331 positive regulation of extracellular matrix constituent secretion 4.306134e-4
GO:0061049 cell growth involved in cardiac muscle cell development 4.306134e-4
GO:0001998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure 4.306134e-4
GO:0014873 response to muscle activity involved in regulation of muscle adaptation 4.306134e-4
GO:0008625 induction of apoptosis via death domain receptors 4.331134e-4
GO:0032370 positive regulation of lipid transport 4.378725e-4
GO:0043163 cell envelope organization 4.497320e-4
GO:0042488 positive regulation of odontogenesis of dentine-containing tooth 4.497320e-4
GO:0033860 regulation of NAD(P)H oxidase activity 4.497320e-4
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity 4.614331e-4
GO:0018963 phthalate metabolic process 4.636702e-4
GO:0090311 regulation of protein deacetylation 4.642800e-4
GO:0060390 regulation of SMAD protein import into nucleus 4.715440e-4
GO:0042493 response to drug 4.723767e-4
GO:0044062 regulation of excretion 4.745868e-4
GO:0042743 hydrogen peroxide metabolic process 4.778165e-4
GO:0060762 regulation of branching involved in mammary gland duct morphogenesis 4.896154e-4
GO:0030217 T cell differentiation 4.949817e-4
GO:0071276 cellular response to cadmium ion 4.957372e-4
GO:0002019 regulation of renal output by angiotensin 5.159097e-4
GO:0048872 homeostasis of number of cells 5.224544e-4
GO:0010610 regulation of mRNA stability involved in response to stress 5.265638e-4
GO:0033209 tumor necrosis factor-mediated signaling pathway 5.361571e-4
GO:0006691 leukotriene metabolic process 5.399727e-4
GO:0060996 dendritic spine development 5.404047e-4
GO:0006625 protein targeting to peroxisome 5.404047e-4
GO:0060611 mammary gland fat development 5.493065e-4
GO:0046173 polyol biosynthetic process 5.493065e-4
GO:0019049 evasion of host defenses by virus 5.500878e-4
GO:0032674 regulation of interleukin-5 production 5.614188e-4
GO:0003417 growth plate cartilage development 5.662074e-4
GO:0071870 cellular response to catecholamine stimulus 5.667304e-4
GO:0045905 positive regulation of translational termination 5.667304e-4
GO:0045901 positive regulation of translational elongation 5.667304e-4
GO:0006452 translational frameshifting 5.667304e-4
GO:0032892 positive regulation of organic acid transport 5.773925e-4
GO:0010982 regulation of high-density lipoprotein particle clearance 5.820420e-4
GO:0030730 sequestering of triglyceride 5.890564e-4
GO:0045086 positive regulation of interleukin-2 biosynthetic process 5.911313e-4
GO:0045994 positive regulation of translational initiation by iron 5.913001e-4
GO:0002037 negative regulation of L-glutamate transport 5.913001e-4
GO:0070375 BMK cascade 5.981001e-4
GO:0046645 positive regulation of gamma-delta T cell activation 5.983799e-4
GO:0045080 positive regulation of chemokine biosynthetic process 5.989670e-4
GO:0030852 regulation of granulocyte differentiation 6.020882e-4
GO:0021658 rhombomere 3 morphogenesis 6.132175e-4
GO:0071705 nitrogen compound transport 6.227037e-4
GO:0043380 regulation of memory T cell differentiation 6.277991e-4
GO:0009991 response to extracellular stimulus 6.303959e-4
GO:0018879 biphenyl metabolic process 6.304500e-4
GO:0071280 cellular response to copper ion 6.416861e-4
GO:0048839 inner ear development 6.428739e-4
GO:0009235 cobalamin metabolic process 6.498730e-4
GO:0045717 negative regulation of fatty acid biosynthetic process 6.513671e-4
GO:0007585 respiratory gaseous exchange 6.539918e-4
GO:0014070 response to organic cyclic compound 6.569549e-4
GO:0019060 intracellular transport of viral proteins in host cell 6.585369e-4
GO:0006749 glutathione metabolic process 6.634498e-4
GO:0010034 response to acetate 6.660072e-4
GO:0048569 post-embryonic organ development 6.709849e-4
GO:0033683 nucleotide-excision repair, DNA incision 6.838142e-4
GO:0031296 B cell costimulation 6.947089e-4
GO:0031104 dendrite regeneration 6.947089e-4
GO:0031960 response to corticosteroid stimulus 6.969457e-4
GO:0034384 high-density lipoprotein particle clearance 6.982524e-4
GO:0015872 dopamine transport 7.010737e-4
GO:0045588 positive regulation of gamma-delta T cell differentiation 7.017080e-4
GO:0002679 respiratory burst involved in defense response 7.075463e-4
GO:0009635 response to herbicide 7.087808e-4
GO:0051092 positive regulation of NF-kappaB transcription factor activity 7.127783e-4
GO:0003416 endochondral bone growth 7.205879e-4
GO:0001909 leukocyte mediated cytotoxicity 7.351736e-4
GO:0031347 regulation of defense response 7.370630e-4
GO:0048298 positive regulation of isotype switching to IgA isotypes 7.614110e-4
GO:0014829 vascular smooth muscle contraction 7.661973e-4
GO:0032515 negative regulation of phosphoprotein phosphatase activity 7.766940e-4
GO:0002682 regulation of immune system process 7.878675e-4
GO:0032210 regulation of telomere maintenance via telomerase 7.999275e-4
GO:0002828 regulation of type 2 immune response 8.094000e-4
GO:0045624 positive regulation of T-helper cell differentiation 8.111679e-4
GO:0042267 natural killer cell mediated cytotoxicity 8.220215e-4
GO:0051004 regulation of lipoprotein lipase activity 8.362900e-4
GO:0014012 peripheral nervous system axon regeneration 8.579984e-4
GO:0042994 cytoplasmic sequestering of transcription factor 8.637364e-4
GO:0070163 regulation of adiponectin secretion 8.649280e-4
GO:0044240 multicellular organismal lipid catabolic process 8.697774e-4
GO:0006689 ganglioside catabolic process 8.746573e-4
GO:0050778 positive regulation of immune response 8.788156e-4
GO:0043174 nucleoside salvage 8.837584e-4
GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 8.841795e-4
GO:0050710 negative regulation of cytokine secretion 8.843550e-4
GO:0045625 regulation of T-helper 1 cell differentiation 8.852737e-4
GO:0040040 thermosensory behavior 8.860205e-4
GO:0061053 somite development 8.914672e-4
GO:0043300 regulation of leukocyte degranulation 8.943061e-4
GO:0010310 regulation of hydrogen peroxide metabolic process 8.999433e-4
GO:0045136 development of secondary sexual characteristics 9.157388e-4
GO:0032226 positive regulation of synaptic transmission, dopaminergic 9.236201e-4
GO:0045005 maintenance of fidelity involved in DNA-dependent DNA replication 9.254484e-4
GO:0019724 B cell mediated immunity 9.385268e-4
GO:0050994 regulation of lipid catabolic process 9.397650e-4
GO:0022415 viral reproductive process 9.547912e-4
GO:0031667 response to nutrient levels 9.591457e-4
GO:0015670 carbon dioxide transport 9.605507e-4
GO:0045629 negative regulation of T-helper 2 cell differentiation 9.607973e-4
GO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose 9.725688e-4
GO:0001756 somitogenesis 9.885943e-4
GO:0061302 smooth muscle cell-matrix adhesion 1.004620e-3
GO:0006669 sphinganine-1-phosphate biosynthetic process 1.004620e-3
GO:0045472 response to ether 1.004620e-3
GO:0032736 positive regulation of interleukin-13 production 1.014066e-3
GO:0015837 amine transport 1.034698e-3
GO:0006000 fructose metabolic process 1.059393e-3
GO:0070935 3'-UTR-mediated mRNA stabilization 1.062354e-3
GO:0033700 phospholipid efflux 1.071664e-3
GO:0021569 rhombomere 3 development 1.081506e-3
GO:0019218 regulation of steroid metabolic process 1.090610e-3
GO:0007422 peripheral nervous system development 1.103374e-3
GO:0045060 negative thymic T cell selection 1.113728e-3
GO:0021782 glial cell development 1.122306e-3
GO:0072337 modified amino acid transport 1.138073e-3
GO:0002252 immune effector process 1.140994e-3
GO:0034330 cell junction organization 1.143280e-3
GO:0006261 DNA-dependent DNA replication 1.156658e-3
GO:0045006 DNA deamination 1.161216e-3
GO:0043973 histone H3-K4 acetylation 1.176442e-3
GO:0046985 positive regulation of hemoglobin biosynthetic process 1.176442e-3
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 1.176442e-3
GO:0045580 regulation of T cell differentiation 1.180091e-3
GO:0009113 purine base biosynthetic process 1.185841e-3
GO:0042487 regulation of odontogenesis of dentine-containing tooth 1.190383e-3
GO:0002724 regulation of T cell cytokine production 1.190383e-3
GO:0000302 response to reactive oxygen species 1.195307e-3
GO:0000093 mitotic telophase 1.195890e-3
GO:0007109 cytokinesis, completion of separation 1.198873e-3
GO:0045835 negative regulation of meiosis 1.201076e-3
GO:0046637 regulation of alpha-beta T cell differentiation 1.230484e-3
GO:0070383 DNA cytosine deamination 1.260684e-3
GO:0035461 vitamin transmembrane transport 1.261344e-3
GO:0035470 positive regulation of vascular wound healing 1.261344e-3
GO:0015747 urate transport 1.261344e-3
GO:0014896 muscle hypertrophy 1.262107e-3
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 1.269689e-3
GO:0015879 carnitine transport 1.274455e-3
GO:0045945 positive regulation of transcription from RNA polymerase III promoter 1.280451e-3
GO:0006855 drug transmembrane transport 1.280451e-3
GO:0034224 cellular response to zinc ion starvation 1.292161e-3
GO:0032212 positive regulation of telomere maintenance via telomerase 1.306226e-3
GO:0010226 response to lithium ion 1.325037e-3
GO:0051220 cytoplasmic sequestering of protein 1.334950e-3
GO:0042756 drinking behavior 1.337584e-3
GO:0006021 inositol biosynthetic process 1.358852e-3
GO:0006636 unsaturated fatty acid biosynthetic process 1.378061e-3
GO:0060133 somatotropin secreting cell development 1.387504e-3
GO:0001805 positive regulation of type III hypersensitivity 1.387504e-3
GO:0002431 Fc receptor mediated stimulatory signaling pathway 1.387504e-3
GO:0033127 regulation of histone phosphorylation 1.392004e-3
GO:0034375 high-density lipoprotein particle remodeling 1.412272e-3
GO:0046463 acylglycerol biosynthetic process 1.412631e-3
GO:0019264 glycine biosynthetic process from serine 1.457107e-3
GO:0006892 post-Golgi vesicle-mediated transport 1.464736e-3
GO:0032673 regulation of interleukin-4 production 1.468538e-3
GO:0016255 attachment of GPI anchor to protein 1.490699e-3
GO:0045599 negative regulation of fat cell differentiation 1.493179e-3
GO:0046340 diacylglycerol catabolic process 1.499211e-3
GO:0045988 negative regulation of striated muscle contraction 1.520163e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0042744 hydrogen peroxide catabolic process 5.185306e-13
GO:0030300 regulation of intestinal cholesterol absorption 6.269787e-12
GO:0002385 mucosal immune response 3.144490e-11
GO:0032321 positive regulation of Rho GTPase activity 5.482296e-11
GO:0002251 organ or tissue specific immune response 1.130536e-10
GO:0043088 regulation of Cdc42 GTPase activity 1.175023e-10
GO:0044240 multicellular organismal lipid catabolic process 1.562778e-10
GO:0043089 positive regulation of Cdc42 GTPase activity 1.974241e-10
GO:0048298 positive regulation of isotype switching to IgA isotypes 5.720533e-10
GO:0043154 negative regulation of caspase activity 1.820626e-9
GO:0006982 response to lipid hydroperoxide 6.592508e-9
GO:0055090 acylglycerol homeostasis 1.369111e-8
GO:0010896 regulation of triglyceride catabolic process 1.576552e-8
GO:0002227 innate immune response in mucosa 3.485934e-8
GO:0032319 regulation of Rho GTPase activity 4.706419e-8
GO:0043547 positive regulation of GTPase activity 5.275439e-8
GO:0042743 hydrogen peroxide metabolic process 5.550129e-8
GO:0007021 tubulin complex assembly 8.067072e-8
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 9.517364e-8
GO:0015914 phospholipid transport 9.968131e-8
GO:0042992 negative regulation of transcription factor import into nucleus 2.079397e-7
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 2.591253e-7
GO:0033344 cholesterol efflux 2.781950e-7
GO:0050748 negative regulation of lipoprotein metabolic process 3.611338e-7
GO:0072593 reactive oxygen species metabolic process 5.015003e-7
GO:0010898 positive regulation of triglyceride catabolic process 5.438222e-7
GO:0033700 phospholipid efflux 5.628779e-7
GO:0050994 regulation of lipid catabolic process 5.646225e-7
GO:0045662 negative regulation of myoblast differentiation 5.864532e-7
GO:0010873 positive regulation of cholesterol esterification 6.009654e-7
GO:0046470 phosphatidylcholine metabolic process 8.137549e-7
GO:0051534 negative regulation of NFAT protein import into nucleus 1.038935e-6
GO:0051403 stress-activated MAPK cascade 1.075540e-6
GO:0035306 positive regulation of dephosphorylation 2.587709e-6
GO:0007602 phototransduction 3.240900e-6
GO:0042994 cytoplasmic sequestering of transcription factor 3.556745e-6
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 3.703554e-6
GO:0042308 negative regulation of protein import into nucleus 4.125133e-6
GO:0035307 positive regulation of protein dephosphorylation 4.153450e-6
GO:0050764 regulation of phagocytosis 4.370106e-6
GO:0032862 activation of Rho GTPase activity 4.498705e-6
GO:0051006 positive regulation of lipoprotein lipase activity 4.665190e-6
GO:0032374 regulation of cholesterol transport 4.992785e-6
GO:0032864 activation of Cdc42 GTPase activity 5.147134e-6
GO:0051004 regulation of lipoprotein lipase activity 5.264659e-6
GO:0051336 regulation of hydrolase activity 5.790691e-6
GO:0050766 positive regulation of phagocytosis 6.117115e-6
GO:0044058 regulation of digestive system process 6.510056e-6
GO:0034442 regulation of lipoprotein oxidation 6.525756e-6
GO:0044241 lipid digestion 6.564297e-6
GO:0014047 glutamate secretion 6.594171e-6
GO:0046940 nucleoside monophosphate phosphorylation 7.208521e-6
GO:0050668 positive regulation of homocysteine metabolic process 7.208521e-6
GO:0045796 negative regulation of intestinal cholesterol absorption 7.208521e-6
GO:0045963 negative regulation of dopamine metabolic process 7.208521e-6
GO:0010949 negative regulation of intestinal phytosterol absorption 7.208521e-6
GO:0051148 negative regulation of muscle cell differentiation 1.119937e-5
GO:0006540 glutamate decarboxylation to succinate 1.136016e-5
GO:0002155 regulation of thyroid hormone mediated signaling pathway 1.136016e-5
GO:2000826 regulation of heart morphogenesis 1.246123e-5
GO:0046530 photoreceptor cell differentiation 1.274645e-5
GO:0000305 response to oxygen radical 1.301674e-5
GO:0032210 regulation of telomere maintenance via telomerase 1.373199e-5
GO:0006094 gluconeogenesis 1.381709e-5
GO:0051048 negative regulation of secretion 1.600786e-5
GO:0072668 tubulin complex biogenesis 1.695082e-5
GO:0051220 cytoplasmic sequestering of protein 1.707344e-5
GO:0090084 negative regulation of inclusion body assembly 1.780180e-5
GO:0018364 peptidyl-glutamine methylation 1.851281e-5
GO:0016191 synaptic vesicle uncoating 1.851281e-5
GO:0051345 positive regulation of hydrolase activity 1.903436e-5
GO:0050746 regulation of lipoprotein metabolic process 2.010565e-5
GO:0031440 regulation of mRNA 3'-end processing 2.129829e-5
GO:0010936 negative regulation of macrophage cytokine production 2.450308e-5
GO:0043691 reverse cholesterol transport 2.475515e-5
GO:0090086 negative regulation of protein deubiquitination 2.665340e-5
GO:0051081 nuclear envelope disassembly 2.748102e-5
GO:0045807 positive regulation of endocytosis 2.834089e-5
GO:0010466 negative regulation of peptidase activity 2.848762e-5
GO:0016081 synaptic vesicle docking involved in exocytosis 3.072561e-5
GO:0050434 positive regulation of viral transcription 3.092647e-5
GO:0046477 glycosylceramide catabolic process 3.240635e-5
GO:0033124 regulation of GTP catabolic process 3.286393e-5
GO:0010872 regulation of cholesterol esterification 3.435423e-5
GO:0043087 regulation of GTPase activity 3.532807e-5
GO:0010312 detoxification of zinc ion 3.810149e-5
GO:0045925 positive regulation of female receptivity 3.922218e-5
GO:0035674 tricarboxylic acid transmembrane transport 4.130779e-5
GO:0007565 female pregnancy 4.345104e-5
GO:0030100 regulation of endocytosis 4.480192e-5
GO:0006298 mismatch repair 4.627216e-5
GO:0006756 AMP phosphorylation 4.731972e-5
GO:0032320 positive regulation of Ras GTPase activity 5.028497e-5
GO:0032007 negative regulation of TOR signaling cascade 5.872902e-5
GO:0009201 ribonucleoside triphosphate biosynthetic process 5.936608e-5
GO:0042482 positive regulation of odontogenesis 6.277712e-5
GO:0031109 microtubule polymerization or depolymerization 6.300741e-5
GO:0001845 phagolysosome assembly 6.545072e-5
GO:0010831 positive regulation of myotube differentiation 6.848357e-5
GO:0048242 epinephrine secretion 6.949021e-5
GO:0006754 ATP biosynthetic process 7.230596e-5
GO:0019430 removal of superoxide radicals 7.721152e-5
GO:0001754 eye photoreceptor cell differentiation 7.812165e-5
GO:0016064 immunoglobulin mediated immune response 7.897676e-5
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 8.120498e-5
GO:0032856 activation of Ras GTPase activity 8.153406e-5
GO:0046839 phospholipid dephosphorylation 8.264729e-5
GO:0051346 negative regulation of hydrolase activity 8.509484e-5
GO:0016125 sterol metabolic process 8.562914e-5
GO:0019724 B cell mediated immunity 8.856812e-5
GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis 8.882149e-5
GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 9.199066e-5
GO:0009817 defense response to fungus, incompatible interaction 9.199066e-5
GO:0097107 postsynaptic density assembly 9.199066e-5
GO:0060561 apoptosis involved in morphogenesis 9.550357e-5
GO:0007131 reciprocal meiotic recombination 1.006131e-4
GO:0009142 nucleoside triphosphate biosynthetic process 1.009656e-4
GO:0032232 negative regulation of actin filament bundle assembly 1.009676e-4
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 1.136045e-4
GO:0035928 rRNA import into mitochondrion 1.136045e-4
GO:0002426 immunoglobulin production in mucosal tissue 1.150034e-4
GO:0006448 regulation of translational elongation 1.150034e-4
GO:0008594 photoreceptor cell morphogenesis 1.202934e-4
GO:0021592 fourth ventricle development 1.209682e-4
GO:2000378 negative regulation of reactive oxygen species metabolic process 1.216805e-4
GO:0090189 regulation of branching involved in ureteric bud morphogenesis 1.220407e-4
GO:2000178 negative regulation of neural precursor cell proliferation 1.246398e-4
GO:0051261 protein depolymerization 1.255601e-4
GO:0034763 negative regulation of transmembrane transport 1.278914e-4
GO:0042306 regulation of protein import into nucleus 1.315899e-4
GO:0003266 regulation of secondary heart field cardioblast proliferation 1.372003e-4
GO:0072200 negative regulation of mesenchymal cell proliferation involved in ureter development 1.428286e-4
GO:0072198 mesenchymal cell proliferation involved in ureter development 1.428286e-4
GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis 1.428286e-4
GO:0072138 mesenchymal cell proliferation involved in ureteric bud development 1.428286e-4
GO:0072192 ureter epithelial cell differentiation 1.428286e-4
GO:2000007 negative regulation of metanephric comma-shaped body morphogenesis 1.428286e-4
GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis 1.428286e-4
GO:0072101 specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway 1.428286e-4
GO:2000005 negative regulation of metanephric S-shaped body morphogenesis 1.428286e-4
GO:0090194 negative regulation of glomerulus development 1.428286e-4
GO:0055020 positive regulation of cardiac muscle fiber development 1.428286e-4
GO:0072097 negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway 1.428286e-4
GO:0048392 intermediate mesodermal cell differentiation 1.428286e-4
GO:0007500 mesodermal cell fate determination 1.428286e-4
GO:0060503 bud dilation involved in lung branching 1.428286e-4
GO:0060502 epithelial cell proliferation involved in lung morphogenesis 1.428286e-4
GO:0071893 BMP signaling pathway involved in nephric duct formation 1.428286e-4
GO:0061155 pulmonary artery endothelial tube morphogenesis 1.428286e-4
GO:0061151 BMP signaling pathway involved in renal system segmentation 1.428286e-4
GO:0061149 BMP signaling pathway involved in ureter morphogenesis 1.428286e-4
GO:0034103 regulation of tissue remodeling 1.460003e-4
GO:0090207 regulation of triglyceride metabolic process 1.463181e-4
GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction 1.512761e-4
GO:0034614 cellular response to reactive oxygen species 1.597643e-4
GO:0051412 response to corticosterone stimulus 1.623517e-4
GO:0000303 response to superoxide 1.761139e-4
GO:0051224 negative regulation of protein transport 1.821641e-4
GO:0097035 regulation of membrane lipid distribution 1.827962e-4
GO:0006403 RNA localization 1.837178e-4
GO:0042461 photoreceptor cell development 1.839869e-4
GO:0002252 immune effector process 1.889918e-4
GO:0042694 muscle cell fate specification 1.941558e-4
GO:0035990 tendon cell differentiation 1.945376e-4
GO:0080111 DNA demethylation 1.965835e-4
GO:0002443 leukocyte mediated immunity 1.972211e-4
GO:0045843 negative regulation of striated muscle tissue development 2.182706e-4
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 2.192691e-4
GO:0042135 neurotransmitter catabolic process 2.194029e-4
GO:0009145 purine nucleoside triphosphate biosynthetic process 2.194330e-4
GO:0023021 termination of signal transduction 2.261233e-4
GO:0043401 steroid hormone mediated signaling pathway 2.343944e-4
GO:0050996 positive regulation of lipid catabolic process 2.367556e-4
GO:0002885 positive regulation of hypersensitivity 2.402132e-4
GO:0001778 plasma membrane repair 2.412077e-4
GO:0044243 multicellular organismal catabolic process 2.519542e-4
GO:0000045 autophagic vacuole assembly 2.519542e-4
GO:0070328 triglyceride homeostasis 2.530546e-4
GO:0032984 macromolecular complex disassembly 2.530546e-4
GO:0019319 hexose biosynthetic process 2.540063e-4
GO:0002238 response to molecule of fungal origin 2.581668e-4
GO:0010830 regulation of myotube differentiation 2.601682e-4
GO:0006012 galactose metabolic process 2.633941e-4
GO:0008203 cholesterol metabolic process 2.666610e-4
GO:0048742 regulation of skeletal muscle fiber development 2.747457e-4
GO:0006419 alanyl-tRNA aminoacylation 2.869637e-4
GO:0003130 BMP signaling pathway involved in heart induction 2.869637e-4
GO:0090076 relaxation of skeletal muscle 2.923875e-4
GO:0032470 elevation of endoplasmic reticulum calcium ion concentration 2.923875e-4
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.992977e-4
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 3.038640e-4
GO:0016322 neuron remodeling 3.042457e-4
GO:0007341 penetration of zona pellucida 3.047716e-4
GO:0015931 nucleobase-containing compound transport 3.060623e-4
GO:0002756 MyD88-independent toll-like receptor signaling pathway 3.110841e-4
GO:0001579 medium-chain fatty acid transport 3.110841e-4
GO:0033121 regulation of purine nucleotide catabolic process 3.112648e-4
GO:0051532 regulation of NFAT protein import into nucleus 3.218988e-4
GO:0072095 regulation of branch elongation involved in ureteric bud branching 3.221319e-4
GO:0000395 nuclear mRNA 5'-splice site recognition 3.241278e-4
GO:0006406 mRNA export from nucleus 3.266650e-4
GO:0045655 regulation of monocyte differentiation 3.276432e-4
GO:0032488 Cdc42 protein signal transduction 3.276432e-4
GO:0032375 negative regulation of cholesterol transport 3.330423e-4
GO:0052548 regulation of endopeptidase activity 3.438605e-4
GO:0009583 detection of light stimulus 3.504999e-4
GO:0007221 positive regulation of transcription of Notch receptor target 3.511345e-4
GO:0002636 positive regulation of germinal center formation 3.511345e-4
GO:2000117 negative regulation of cysteine-type endopeptidase activity 3.544160e-4
GO:0051176 positive regulation of sulfur metabolic process 3.544160e-4
GO:0050926 regulation of positive chemotaxis 3.590293e-4
GO:0050663 cytokine secretion 3.648169e-4
GO:0021678 third ventricle development 3.648262e-4
GO:0045657 positive regulation of monocyte differentiation 3.648262e-4
GO:0072273 metanephric nephron morphogenesis 3.755705e-4
GO:0042339 keratan sulfate metabolic process 3.779122e-4
GO:0046823 negative regulation of nucleocytoplasmic transport 3.871763e-4
GO:0042424 catecholamine catabolic process 3.990625e-4
GO:0048635 negative regulation of muscle organ development 4.017628e-4
GO:0016576 histone dephosphorylation 4.068895e-4
GO:0035993 deltoid tuberosity development 4.141990e-4
GO:0002920 regulation of humoral immune response 4.469853e-4
GO:0006207 'de novo' pyrimidine base biosynthetic process 4.567946e-4
GO:0006984 ER-nucleus signaling pathway 4.726278e-4
GO:0006405 RNA export from nucleus 4.738020e-4
GO:0042304 regulation of fatty acid biosynthetic process 4.922739e-4
GO:0045723 positive regulation of fatty acid biosynthetic process 5.056548e-4
GO:0019637 organophosphate metabolic process 5.136356e-4
GO:0045619 regulation of lymphocyte differentiation 5.395416e-4
GO:0065005 protein-lipid complex assembly 5.564553e-4
GO:0002275 myeloid cell activation involved in immune response 5.634366e-4
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 5.696504e-4
GO:0050658 RNA transport 5.707570e-4
GO:0009755 hormone-mediated signaling pathway 5.838271e-4
GO:0001555 oocyte growth 5.893737e-4
GO:0035510 DNA dealkylation 6.150140e-4
GO:0006213 pyrimidine nucleoside metabolic process 6.259094e-4
GO:0045601 regulation of endothelial cell differentiation 6.315155e-4
GO:0035023 regulation of Rho protein signal transduction 6.338410e-4
GO:0044092 negative regulation of molecular function 6.426016e-4
GO:0043932 ossification involved in bone remodeling 6.490235e-4
GO:0006883 cellular sodium ion homeostasis 6.490235e-4
GO:0060591 chondroblast differentiation 6.497935e-4
GO:0051026 chiasma assembly 6.497935e-4
GO:0045113 regulation of integrin biosynthetic process 6.940799e-4
GO:0051639 actin filament network formation 6.940799e-4
GO:0032571 response to vitamin K 6.940799e-4
GO:0045618 positive regulation of keratinocyte differentiation 6.987890e-4
GO:0090208 positive regulation of triglyceride metabolic process 7.062909e-4
GO:0045621 positive regulation of lymphocyte differentiation 7.098728e-4
GO:0051096 positive regulation of helicase activity 7.195264e-4
GO:0060010 Sertoli cell fate commitment 7.257113e-4
GO:0043241 protein complex disassembly 7.298009e-4
GO:0006543 glutamine catabolic process 7.328433e-4
GO:0070375 BMK cascade 7.366144e-4
GO:0009586 rhodopsin mediated phototransduction 7.366144e-4
GO:0032231 regulation of actin filament bundle assembly 7.501413e-4
GO:0051126 negative regulation of actin nucleation 7.618255e-4
GO:0010954 positive regulation of protein processing 7.755749e-4
GO:0046364 monosaccharide biosynthetic process 7.827059e-4
GO:0006909 phagocytosis 7.838776e-4
GO:0009912 auditory receptor cell fate commitment 7.849607e-4
GO:0045661 regulation of myoblast differentiation 7.931734e-4
GO:0051385 response to mineralocorticoid stimulus 8.010086e-4
GO:0002449 lymphocyte mediated immunity 8.042388e-4
GO:0001935 endothelial cell proliferation 8.206451e-4
GO:0045408 regulation of interleukin-6 biosynthetic process 8.273528e-4
GO:0034976 response to endoplasmic reticulum stress 8.421355e-4
GO:0007266 Rho protein signal transduction 8.517317e-4
GO:0060381 positive regulation of single-stranded telomeric DNA binding 8.536718e-4
GO:0035865 cellular response to potassium ion 8.536718e-4
GO:0034651 cortisol biosynthetic process 8.536718e-4
GO:0022400 regulation of rhodopsin mediated signaling pathway 8.536718e-4
GO:0034623 cellular macromolecular complex disassembly 9.010666e-4
GO:0050432 catecholamine secretion 9.042866e-4
GO:0031442 positive regulation of mRNA 3'-end processing 9.042866e-4
GO:0071422 succinate transmembrane transport 9.192263e-4
GO:0006694 steroid biosynthetic process 9.268913e-4
GO:0001798 positive regulation of type IIa hypersensitivity 9.276166e-4
GO:0051051 negative regulation of transport 9.282843e-4
GO:0051028 mRNA transport 9.465188e-4
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 9.522472e-4
GO:0032331 negative regulation of chondrocyte differentiation 9.848740e-4
GO:0002526 acute inflammatory response 1.012055e-3
GO:2000116 regulation of cysteine-type endopeptidase activity 1.012641e-3
GO:0050927 positive regulation of positive chemotaxis 1.036019e-3
GO:0034637 cellular carbohydrate biosynthetic process 1.044603e-3
GO:0006290 pyrimidine dimer repair 1.050904e-3
GO:0014015 positive regulation of gliogenesis 1.053431e-3
GO:0043623 cellular protein complex assembly 1.053561e-3
GO:0042462 eye photoreceptor cell development 1.054694e-3
GO:0060457 negative regulation of digestive system process 1.073098e-3
GO:0043586 tongue development 1.104356e-3
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 1.118738e-3
GO:0014874 response to stimulus involved in regulation of muscle adaptation 1.118738e-3
GO:2000974 negative regulation of pro-B cell differentiation 1.136077e-3
GO:0006868 glutamine transport 1.136077e-3
GO:0045579 positive regulation of B cell differentiation 1.163635e-3
GO:0071956 cellular component maintenance at cellular level 1.178554e-3
GO:0030263 apoptotic chromosome condensation 1.192951e-3
GO:0048554 positive regulation of metalloenzyme activity 1.208022e-3
GO:0090317 negative regulation of intracellular protein transport 1.242883e-3
GO:0031100 organ regeneration 1.266937e-3
GO:0051497 negative regulation of stress fiber assembly 1.273866e-3
GO:0060427 lung connective tissue development 1.280597e-3
GO:0006680 glucosylceramide catabolic process 1.280597e-3
GO:0045332 phospholipid translocation 1.299072e-3
GO:0042420 dopamine catabolic process 1.299072e-3
GO:0042542 response to hydrogen peroxide 1.330076e-3
GO:0021993 initiation of neural tube closure 1.336088e-3
GO:0030719 P granule organization 1.339427e-3
GO:0045830 positive regulation of isotype switching 1.340732e-3
GO:0060161 positive regulation of dopamine receptor signaling pathway 1.373408e-3
GO:0032425 positive regulation of mismatch repair 1.373408e-3
GO:0031329 regulation of cellular catabolic process 1.374712e-3
GO:0035552 oxidative single-stranded DNA demethylation 1.382524e-3
GO:0032277 negative regulation of gonadotropin secretion 1.382524e-3
GO:0061154 endothelial tube morphogenesis 1.386530e-3
GO:0061047 positive regulation of branching involved in lung morphogenesis 1.386530e-3
GO:0051168 nuclear export 1.388648e-3
GO:0050921 positive regulation of chemotaxis 1.390787e-3
GO:0006446 regulation of translational initiation 1.402954e-3
GO:0009065 glutamine family amino acid catabolic process 1.495472e-3
GO:0007265 Ras protein signal transduction 1.510236e-3
GO:0030178 negative regulation of Wnt receptor signaling pathway 1.525222e-3
GO:0061311 cell surface receptor linked signaling pathway involved in heart development 1.591284e-3
GO:0032103 positive regulation of response to external stimulus 1.606318e-3
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 1.613625e-3
GO:0051642 centrosome localization 1.614114e-3
GO:0034104 negative regulation of tissue remodeling 1.626261e-3
GO:0070212 protein poly-ADP-ribosylation 1.627103e-3
GO:0042789 mRNA transcription from RNA polymerase II promoter 1.627103e-3
GO:0032212 positive regulation of telomere maintenance via telomerase 1.627103e-3
GO:0038027 apolipoprotein A-I-mediated signaling pathway 1.627103e-3
GO:0045217 cell-cell junction maintenance 1.648597e-3
GO:0032367 intracellular cholesterol transport 1.648597e-3
GO:0007405 neuroblast proliferation 1.658920e-3
GO:0014819 regulation of skeletal muscle contraction 1.725233e-3
GO:0021670 lateral ventricle development 1.769126e-3
GO:0048593 camera-type eye morphogenesis 1.772080e-3
GO:0045409 negative regulation of interleukin-6 biosynthetic process 1.773155e-3
GO:0045143 homologous chromosome segregation 1.773155e-3
GO:0070301 cellular response to hydrogen peroxide 1.839522e-3
GO:0006538 glutamate catabolic process 1.853274e-3
GO:0072513 positive regulation of secondary heart field cardioblast proliferation 1.853274e-3
GO:0051095 regulation of helicase activity 1.853274e-3
GO:0046850 regulation of bone remodeling 1.860304e-3
GO:0018298 protein-chromophore linkage 1.887257e-3
GO:0046967 cytosol to ER transport 1.892880e-3
GO:0060611 mammary gland fat development 1.892880e-3
GO:0019060 intracellular transport of viral proteins in host cell 1.892880e-3
GO:0010918 positive regulation of mitochondrial membrane potential 1.892880e-3
GO:0031424 keratinization 1.923739e-3
GO:0003407 neural retina development 1.927903e-3
GO:0051223 regulation of protein transport 1.954971e-3
GO:0010310 regulation of hydrogen peroxide metabolic process 1.956893e-3
GO:0050871 positive regulation of B cell activation 2.028430e-3
GO:0035725 sodium ion transmembrane transport 2.036893e-3
GO:0007256 activation of JNKK activity 2.053451e-3
GO:0045603 positive regulation of endothelial cell differentiation 2.072470e-3
GO:0072124 regulation of glomerular mesangial cell proliferation 2.080787e-3
GO:0016126 sterol biosynthetic process 2.126416e-3
GO:0006370 mRNA capping 2.161507e-3
GO:0035304 regulation of protein dephosphorylation 2.185305e-3
GO:0007173 epidermal growth factor receptor signaling pathway 2.216487e-3
GO:0016578 histone deubiquitination 2.230819e-3
GO:2000377 regulation of reactive oxygen species metabolic process 2.320231e-3
GO:0002250 adaptive immune response 2.324745e-3
GO:0048592 eye morphogenesis 2.338629e-3
GO:0045872 positive regulation of rhodopsin gene expression 2.342597e-3
GO:0001682 tRNA 5'-leader removal 2.342597e-3
GO:0043252 sodium-independent organic anion transport 2.342597e-3
GO:0035048 splicing factor protein import into nucleus 2.342597e-3
GO:0016078 tRNA catabolic process 2.342597e-3
GO:0021528 commissural neuron differentiation in spinal cord 2.342597e-3
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 2.348828e-3
GO:0072539 T-helper 17 cell differentiation 2.376093e-3
GO:0002536 respiratory burst involved in inflammatory response 2.376093e-3
GO:0030903 notochord development 2.413537e-3
GO:0007184 SMAD protein import into nucleus 2.413537e-3
GO:0006882 cellular zinc ion homeostasis 2.431822e-3
GO:0071599 otic vesicle development 2.439926e-3
GO:0042274 ribosomal small subunit biogenesis 2.477396e-3
GO:0032211 negative regulation of telomere maintenance via telomerase 2.486330e-3
GO:0015886 heme transport 2.486330e-3
GO:0009299 mRNA transcription 2.486330e-3
GO:0030046 parallel actin filament bundle assembly 2.493892e-3
GO:0002513 tolerance induction to self antigen 2.493892e-3
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity 2.515911e-3
GO:0045218 zonula adherens maintenance 2.539261e-3
GO:0050917 sensory perception of umami taste 2.539261e-3
GO:0070509 calcium ion import 2.545928e-3
GO:0045905 positive regulation of translational termination 2.558416e-3
GO:0006452 translational frameshifting 2.558416e-3
GO:0045901 positive regulation of translational elongation 2.558416e-3
GO:0007028 cytoplasm organization 2.572997e-3
GO:0050792 regulation of viral reproduction 2.599394e-3
GO:0016458 gene silencing 2.601859e-3
GO:0017145 stem cell division 2.635952e-3
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 2.641112e-3
GO:0007406 negative regulation of neuroblast proliferation 2.665527e-3
GO:0048599 oocyte development 2.687711e-3
GO:0072125 negative regulation of glomerular mesangial cell proliferation 2.695344e-3
GO:0046434 organophosphate catabolic process 2.695984e-3
GO:0043086 negative regulation of catalytic activity 2.734970e-3
GO:0000302 response to reactive oxygen species 2.750897e-3
GO:0001970 positive regulation of activation of membrane attack complex 2.777751e-3
GO:0061049 cell growth involved in cardiac muscle cell development 2.822652e-3
GO:0061302 smooth muscle cell-matrix adhesion 2.822652e-3
GO:0014873 response to muscle activity involved in regulation of muscle adaptation 2.822652e-3
GO:0008065 establishment of blood-nerve barrier 2.822652e-3
GO:0003331 positive regulation of extracellular matrix constituent secretion 2.822652e-3
GO:0009450 gamma-aminobutyric acid catabolic process 2.822652e-3
GO:0045580 regulation of T cell differentiation 2.834302e-3
GO:0090257 regulation of muscle system process 2.853857e-3
GO:0009416 response to light stimulus 2.855913e-3
GO:0072050 S-shaped body morphogenesis 2.860541e-3
GO:0072049 comma-shaped body morphogenesis 2.860541e-3
GO:0070141 response to UV-A 2.861051e-3
GO:0045924 regulation of female receptivity 2.876241e-3
GO:0051029 rRNA transport 2.877911e-3
GO:0009620 response to fungus 2.886467e-3
GO:0010951 negative regulation of endopeptidase activity 3.032422e-3
GO:0032957 inositol trisphosphate metabolic process 3.113442e-3
GO:2000243 positive regulation of reproductive process 3.132532e-3
GO:0001658 branching involved in ureteric bud morphogenesis 3.135584e-3
GO:0021591 ventricular system development 3.171776e-3
GO:0043624 cellular protein complex disassembly 3.186334e-3
GO:0006105 succinate metabolic process 3.194016e-3
GO:0034330 cell junction organization 3.229458e-3
GO:0046131 pyrimidine ribonucleoside metabolic process 3.257044e-3
GO:0016032 viral reproduction 3.260345e-3
GO:0033194 response to hydroperoxide 3.298951e-3
GO:0022414 reproductive process 3.303133e-3
GO:0048641 regulation of skeletal muscle tissue development 3.331600e-3
GO:0000003 reproduction 3.341877e-3
GO:0032006 regulation of TOR signaling cascade 3.386759e-3
GO:0070670 response to interleukin-4 3.396106e-3
GO:0032318 regulation of Ras GTPase activity 3.404196e-3
GO:0010269 response to selenium ion 3.423676e-3
GO:0006955 immune response 3.437057e-3
GO:0060391 positive regulation of SMAD protein import into nucleus 3.453331e-3
GO:0070198 protein localization to chromosome, telomeric region 3.463464e-3
GO:0035511 oxidative DNA demethylation 3.463464e-3
GO:0002883 regulation of hypersensitivity 3.488577e-3
GO:0015938 coenzyme A catabolic process 3.555276e-3
GO:0010041 response to iron(III) ion 3.555276e-3
GO:0002897 positive regulation of central B cell tolerance induction 3.555276e-3
GO:0002508 central tolerance induction 3.555276e-3
GO:0009894 regulation of catabolic process 3.630225e-3
GO:0042036 negative regulation of cytokine biosynthetic process 3.653093e-3
GO:0033084 regulation of immature T cell proliferation in thymus 3.670678e-3
GO:0048754 branching morphogenesis of a tube 3.676900e-3
GO:0051788 response to misfolded protein 3.689848e-3
GO:0048715 negative regulation of oligodendrocyte differentiation 3.732031e-3
GO:0000320 re-entry into mitotic cell cycle 3.753063e-3
GO:0045582 positive regulation of T cell differentiation 3.805174e-3
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 3.921007e-3
GO:0008340 determination of adult lifespan 3.924873e-3
GO:0071214 cellular response to abiotic stimulus 3.974188e-3
GO:0060113 inner ear receptor cell differentiation 3.997961e-3
GO:0070989 oxidative demethylation 4.039263e-3
GO:0060621 negative regulation of cholesterol import 4.039263e-3
GO:0000710 meiotic mismatch repair 4.039263e-3
GO:0007386 compartment pattern specification 4.039263e-3
GO:0009260 ribonucleotide biosynthetic process 4.057598e-3
GO:0055025 positive regulation of cardiac muscle tissue development 4.065486e-3
GO:0006401 RNA catabolic process 4.076861e-3
GO:0010876 lipid localization 4.079250e-3
GO:0010625 positive regulation of Schwann cell proliferation 4.086318e-3
GO:0010273 detoxification of copper ion 4.086318e-3
GO:0048251 elastic fiber assembly 4.110069e-3
GO:0002701 negative regulation of production of molecular mediator of immune response 4.110069e-3
GO:0060644 mammary gland epithelial cell differentiation 4.143768e-3
GO:0010212 response to ionizing radiation 4.146352e-3
GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response 4.173831e-3
GO:0046856 phosphatidylinositol dephosphorylation 4.222339e-3
GO:0033233 regulation of protein sumoylation 4.222339e-3
GO:0006071 glycerol metabolic process 4.249506e-3
GO:0005989 lactose biosynthetic process 4.253558e-3
GO:0003158 endothelium development 4.288272e-3
GO:0060440 trachea formation 4.298937e-3
GO:0010159 specification of organ position 4.334697e-3
GO:0060219 camera-type eye photoreceptor cell differentiation 4.342460e-3
GO:0002889 regulation of immunoglobulin mediated immune response 4.365080e-3
GO:0060627 regulation of vesicle-mediated transport 4.397910e-3
GO:0042490 mechanoreceptor differentiation 4.412782e-3
GO:0051156 glucose 6-phosphate metabolic process 4.425550e-3
GO:0006867 asparagine transport 4.425550e-3
GO:0006449 regulation of translational termination 4.425550e-3
GO:0021539 subthalamus development 4.440319e-3
GO:0046782 regulation of viral transcription 4.490004e-3
GO:0003219 cardiac right ventricle formation 4.491004e-3
GO:0032147 activation of protein kinase activity 4.508141e-3
GO:0042133 neurotransmitter metabolic process 4.538419e-3
GO:0007412 axon target recognition 4.572929e-3
GO:0003051 angiotensin-mediated drinking behavior 4.572929e-3
GO:0042439 ethanolamine-containing compound metabolic process 4.581250e-3
GO:2000173 negative regulation of branching morphogenesis of a nerve 4.648894e-3
GO:0070213 protein auto-ADP-ribosylation 4.648894e-3