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Novel motif:90

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name:motif90_TTATATCGC

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0022614 membrane to membrane docking 2.993898e-13
GO:0048806 genitalia development 2.163844e-10
GO:0021568 rhombomere 2 development 2.417592e-10
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 2.699730e-10
GO:0021930 cerebellar granule cell precursor proliferation 2.596228e-9
GO:0043570 maintenance of DNA repeat elements 9.643254e-9
GO:0009107 lipoate biosynthetic process 1.259615e-8
GO:0007598 blood coagulation, extrinsic pathway 5.683842e-8
GO:0007016 cytoskeletal anchoring at plasma membrane 9.226772e-8
GO:0039020 pronephric nephron tubule development 1.074830e-7
GO:0035565 regulation of pronephros size 1.074830e-7
GO:0006266 DNA ligation 2.269627e-7
GO:0035112 genitalia morphogenesis 4.394819e-7
GO:0006437 tyrosyl-tRNA aminoacylation 4.464810e-7
GO:0021546 rhombomere development 4.977584e-7
GO:0032673 regulation of interleukin-4 production 5.258215e-7
GO:0009106 lipoate metabolic process 5.566230e-7
GO:0072181 mesonephric duct formation 6.014399e-7
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 6.136235e-7
GO:0022406 membrane docking 1.042586e-6
GO:0008272 sulfate transport 1.553967e-6
GO:0019319 hexose biosynthetic process 2.274211e-6
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 2.634765e-6
GO:0006303 double-strand break repair via nonhomologous end joining 3.042444e-6
GO:0006094 gluconeogenesis 3.180763e-6
GO:0035411 catenin import into nucleus 4.061677e-6
GO:0072172 mesonephric tubule formation 4.563706e-6
GO:0015074 DNA integration 4.914912e-6
GO:0042249 establishment of planar polarity of embryonic epithelium 5.820170e-6
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 5.985156e-6
GO:0032252 secretory granule localization 6.582915e-6
GO:0043111 replication fork arrest 7.085530e-6
GO:0061017 hepatoblast differentiation 8.037618e-6
GO:0051254 positive regulation of RNA metabolic process 8.566944e-6
GO:0002541 activation of plasma proteins involved in acute inflammatory response 9.455542e-6
GO:0046364 monosaccharide biosynthetic process 1.010975e-5
GO:0030902 hindbrain development 1.012754e-5
GO:0061384 heart trabecular morphogenesis 1.054265e-5
GO:0072095 regulation of branch elongation involved in ureteric bud branching 1.260033e-5
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 1.306279e-5
GO:0060216 definitive hemopoiesis 1.658848e-5
GO:0044334 canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition 1.791305e-5
GO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process 1.791305e-5
GO:0019047 provirus integration 2.092439e-5
GO:0061383 trabecula morphogenesis 2.122545e-5
GO:0090304 nucleic acid metabolic process 2.204447e-5
GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 2.388888e-5
GO:0030194 positive regulation of blood coagulation 2.701980e-5
GO:0032743 positive regulation of interleukin-2 production 3.037183e-5
GO:0006259 DNA metabolic process 3.396422e-5
GO:0048265 response to pain 3.436506e-5
GO:0007159 leukocyte cell-cell adhesion 3.660239e-5
GO:0001826 inner cell mass cell differentiation 3.708568e-5
GO:0070265 necrotic cell death 3.786744e-5
GO:0000726 non-recombinational repair 3.966042e-5
GO:0040019 positive regulation of embryonic development 3.975786e-5
GO:0031328 positive regulation of cellular biosynthetic process 4.095365e-5
GO:0021555 midbrain-hindbrain boundary morphogenesis 4.295199e-5
GO:0045893 positive regulation of transcription, DNA-dependent 4.328907e-5
GO:0002543 activation of blood coagulation via clotting cascade 4.664888e-5
GO:0051176 positive regulation of sulfur metabolic process 4.858305e-5
GO:0048566 embryonic digestive tract development 5.056661e-5
GO:0050820 positive regulation of coagulation 5.148215e-5
GO:0032571 response to vitamin K 5.209259e-5
GO:0010628 positive regulation of gene expression 5.245613e-5
GO:0051386 regulation of nerve growth factor receptor signaling pathway 5.247605e-5
GO:0051447 negative regulation of meiotic cell cycle 5.793983e-5
GO:0048388 endosomal lumen acidification 5.801399e-5
GO:0042762 regulation of sulfur metabolic process 5.815140e-5
GO:0060554 induction of necroptosis of activated-T cells 5.915315e-5
GO:0072171 mesonephric tubule morphogenesis 6.097032e-5
GO:0060437 lung growth 6.166334e-5
GO:0072378 blood coagulation, fibrin clot formation 6.448045e-5
GO:0032753 positive regulation of interleukin-4 production 6.551034e-5
GO:0009891 positive regulation of biosynthetic process 6.553392e-5
GO:0006139 nucleobase-containing compound metabolic process 7.968575e-5
GO:0009949 polarity specification of anterior/posterior axis 8.024269e-5
GO:0044324 regulation of transcription involved in anterior/posterior axis specification 8.024269e-5
GO:0034633 retinol transport 8.204534e-5
GO:0044029 hypomethylation of CpG island 9.389291e-5
GO:2000121 regulation of removal of superoxide radicals 9.621274e-5
GO:0030538 embryonic genitalia morphogenesis 9.647930e-5
GO:0051173 positive regulation of nitrogen compound metabolic process 1.053612e-4
GO:0046666 retinal cell programmed cell death 1.107759e-4
GO:0003222 ventricular trabecular myocardium morphogenesis 1.107759e-4
GO:0006734 NADH metabolic process 1.190933e-4
GO:0048562 embryonic organ morphogenesis 1.218305e-4
GO:0048557 embryonic digestive tract morphogenesis 1.254395e-4
GO:0048625 myoblast cell fate commitment 1.301352e-4
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 1.326272e-4
GO:0030259 lipid glycosylation 1.458310e-4
GO:0002726 positive regulation of T cell cytokine production 1.582258e-4
GO:0002691 regulation of cellular extravasation 1.582258e-4
GO:0072126 positive regulation of glomerular mesangial cell proliferation 1.633605e-4
GO:0071506 cellular response to mycophenolic acid 1.633605e-4
GO:0048641 regulation of skeletal muscle tissue development 1.661906e-4
GO:0031295 T cell costimulation 1.668967e-4
GO:0030317 sperm motility 1.851441e-4
GO:0001714 endodermal cell fate specification 1.858817e-4
GO:0032892 positive regulation of organic acid transport 1.987585e-4
GO:0006560 proline metabolic process 2.261320e-4
GO:0046165 alcohol biosynthetic process 2.338756e-4
GO:0009822 alkaloid catabolic process 2.427929e-4
GO:0060337 type I interferon-mediated signaling pathway 2.577829e-4
GO:0072180 mesonephric duct morphogenesis 2.623482e-4
GO:0048266 behavioral response to pain 2.646364e-4
GO:0046827 positive regulation of protein export from nucleus 2.710778e-4
GO:0016202 regulation of striated muscle tissue development 2.715354e-4
GO:0030193 regulation of blood coagulation 2.722647e-4
GO:0034340 response to type I interferon 2.777516e-4
GO:0006733 oxidoreduction coenzyme metabolic process 2.882369e-4
GO:0048619 embryonic hindgut morphogenesis 2.925771e-4
GO:0006072 glycerol-3-phosphate metabolic process 2.986457e-4
GO:0019362 pyridine nucleotide metabolic process 3.212895e-4
GO:0021986 habenula development 3.262668e-4
GO:0050818 regulation of coagulation 3.302671e-4
GO:0045453 bone resorption 3.304975e-4
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 3.322891e-4
GO:0032024 positive regulation of insulin secretion 3.429725e-4
GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport 3.719344e-4
GO:0070498 interleukin-1-mediated signaling pathway 3.723332e-4
GO:0021903 rostrocaudal neural tube patterning 3.723332e-4
GO:0072110 glomerular mesangial cell proliferation 4.013200e-4
GO:0060058 positive regulation of apoptosis involved in mammary gland involution 4.013200e-4
GO:0010557 positive regulation of macromolecule biosynthetic process 4.025345e-4
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 4.115080e-4
GO:2000124 regulation of endocannabinoid signaling pathway 4.290186e-4
GO:0007600 sensory perception 4.339788e-4
GO:0034337 RNA folding 4.581333e-4
GO:0048634 regulation of muscle organ development 4.699463e-4
GO:0016070 RNA metabolic process 5.116299e-4
GO:0006561 proline biosynthetic process 5.207971e-4
GO:0023019 signal transduction involved in regulation of gene expression 5.290076e-4
GO:0090004 positive regulation of establishment of protein localization in plasma membrane 5.534183e-4
GO:0051387 negative regulation of nerve growth factor receptor signaling pathway 5.737856e-4
GO:0045047 protein targeting to ER 5.833206e-4
GO:0019233 sensory perception of pain 5.969380e-4
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 6.139282e-4
GO:0046496 nicotinamide nucleotide metabolic process 6.210040e-4
GO:0035284 brain segmentation 6.651919e-4
GO:0002724 regulation of T cell cytokine production 6.891768e-4
GO:0072177 mesonephric duct development 7.055460e-4
GO:0072109 glomerular mesangium development 7.055460e-4
GO:0060343 trabecula formation 7.212269e-4
GO:0001711 endodermal cell fate commitment 7.266696e-4
GO:0035883 enteroendocrine cell differentiation 7.304781e-4
GO:0032913 negative regulation of transforming growth factor beta3 production 7.304781e-4
GO:0032600 chemokine receptor transport out of membrane raft 7.304781e-4
GO:0032597 B cell receptor transport into membrane raft 7.304781e-4
GO:0051897 positive regulation of protein kinase B signaling cascade 7.508296e-4
GO:0044030 regulation of DNA methylation 7.714754e-4
GO:0003329 pancreatic PP cell fate commitment 7.768772e-4
GO:0003326 pancreatic A cell fate commitment 7.768772e-4
GO:2000774 positive regulation of cellular senescence 8.217453e-4
GO:0035986 senescence-associated heterochromatin focus formation 8.217453e-4
GO:0060333 interferon-gamma-mediated signaling pathway 8.219582e-4
GO:0043588 skin development 8.977047e-4
GO:0032733 positive regulation of interleukin-10 production 9.128491e-4
GO:0045995 regulation of embryonic development 9.215227e-4
GO:0051155 positive regulation of striated muscle cell differentiation 9.350912e-4
GO:0045597 positive regulation of cell differentiation 9.432026e-4
GO:0007225 patched ligand maturation 9.736953e-4
GO:0002052 positive regulation of neuroblast proliferation 9.770540e-4
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 9.776562e-4
GO:0050850 positive regulation of calcium-mediated signaling 9.861123e-4
GO:0051053 negative regulation of DNA metabolic process 9.939254e-4
GO:0043624 cellular protein complex disassembly 9.972774e-4
GO:0016525 negative regulation of angiogenesis 1.018429e-3
GO:0048568 embryonic organ development 1.044305e-3
GO:0019674 NAD metabolic process 1.047546e-3
GO:0019441 tryptophan catabolic process to kynurenine 1.063827e-3
GO:0000710 meiotic mismatch repair 1.065773e-3
GO:0031016 pancreas development 1.066076e-3
GO:0021512 spinal cord anterior/posterior patterning 1.175202e-3
GO:0006425 glutaminyl-tRNA aminoacylation 1.175202e-3
GO:0007113 endomitotic cell cycle 1.175202e-3
GO:0002200 somatic diversification of immune receptors 1.183685e-3
GO:0016558 protein import into peroxisome matrix 1.239382e-3
GO:0050796 regulation of insulin secretion 1.287398e-3
GO:0030917 midbrain-hindbrain boundary development 1.293517e-3
GO:0033151 V(D)J recombination 1.302459e-3
GO:0021511 spinal cord patterning 1.310945e-3
GO:0046321 positive regulation of fatty acid oxidation 1.327486e-3
GO:0060347 heart trabecula formation 1.335297e-3
GO:0042118 endothelial cell activation 1.344950e-3
GO:0035564 regulation of kidney size 1.344950e-3
GO:0051172 negative regulation of nitrogen compound metabolic process 1.364680e-3
GO:0060743 epithelial cell maturation involved in prostate gland development 1.391744e-3
GO:0051276 chromosome organization 1.417798e-3
GO:0009744 response to sucrose stimulus 1.422015e-3
GO:0035987 endodermal cell differentiation 1.440505e-3
GO:0042663 regulation of endodermal cell fate specification 1.483037e-3
GO:0043241 protein complex disassembly 1.485650e-3
GO:0042254 ribosome biogenesis 1.487250e-3
GO:0045213 neurotransmitter receptor metabolic process 1.500976e-3
GO:0042574 retinal metabolic process 1.560255e-3
GO:0070189 kynurenine metabolic process 1.608586e-3
GO:0046621 negative regulation of organ growth 1.608586e-3
GO:0060249 anatomical structure homeostasis 1.612451e-3
GO:0010867 positive regulation of triglyceride biosynthetic process 1.631275e-3
GO:0032774 RNA biosynthetic process 1.654739e-3
GO:0045444 fat cell differentiation 1.671366e-3
GO:0034393 positive regulation of smooth muscle cell apoptosis 1.709339e-3
GO:0034968 histone lysine methylation 1.723625e-3
GO:0034261 negative regulation of Ras GTPase activity 1.738891e-3
GO:0031117 positive regulation of microtubule depolymerization 1.739763e-3
GO:0033555 multicellular organismal response to stress 1.788468e-3
GO:0034770 histone H4-K20 methylation 1.788758e-3
GO:0030509 BMP signaling pathway 1.818085e-3
GO:0021532 neural tube patterning 1.820457e-3
GO:0032663 regulation of interleukin-2 production 1.879829e-3
GO:2000193 positive regulation of fatty acid transport 1.936305e-3
GO:2000113 negative regulation of cellular macromolecule biosynthetic process 1.953662e-3
GO:0090277 positive regulation of peptide hormone secretion 1.953969e-3
GO:0031018 endocrine pancreas development 1.957743e-3
GO:0006732 coenzyme metabolic process 1.989421e-3
GO:2000438 negative regulation of monocyte extravasation 1.990116e-3
GO:0080154 regulation of fertilization 1.990116e-3
GO:0035724 CD24 biosynthetic process 1.990116e-3
GO:0035723 interleukin-15-mediated signaling pathway 1.990116e-3
GO:0009108 coenzyme biosynthetic process 2.019467e-3
GO:0034637 cellular carbohydrate biosynthetic process 2.022901e-3
GO:2000111 positive regulation of macrophage apoptosis 2.049177e-3
GO:0045722 positive regulation of gluconeogenesis 2.075251e-3
GO:0045445 myoblast differentiation 2.097345e-3
GO:0010832 negative regulation of myotube differentiation 2.141310e-3
GO:0002793 positive regulation of peptide secretion 2.142693e-3
GO:0045165 cell fate commitment 2.168620e-3
GO:0006984 ER-nucleus signaling pathway 2.174828e-3
GO:0061041 regulation of wound healing 2.175062e-3
GO:0050927 positive regulation of positive chemotaxis 2.186500e-3
GO:0048808 male genitalia morphogenesis 2.236424e-3
GO:0010467 gene expression 2.241927e-3
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity 2.285089e-3
GO:0051017 actin filament bundle assembly 2.294073e-3
GO:0060677 ureteric bud elongation 2.334576e-3
GO:0060325 face morphogenesis 2.345463e-3
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 2.357976e-3
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 2.377924e-3
GO:0008633 activation of pro-apoptotic gene products 2.378338e-3
GO:0006367 transcription initiation from RNA polymerase II promoter 2.409286e-3
GO:0002669 positive regulation of T cell anergy 2.435820e-3
GO:0034341 response to interferon-gamma 2.444394e-3
GO:0048743 positive regulation of skeletal muscle fiber development 2.458519e-3
GO:0014003 oligodendrocyte development 2.476231e-3
GO:0019083 viral transcription 2.488006e-3
GO:0071845 cellular component disassembly at cellular level 2.534414e-3
GO:2000026 regulation of multicellular organismal development 2.549968e-3
GO:0071398 cellular response to fatty acid 2.552127e-3
GO:0032274 gonadotropin secretion 2.647812e-3
GO:0051096 positive regulation of helicase activity 2.663626e-3
GO:0001704 formation of primary germ layer 2.721209e-3
GO:0009161 ribonucleoside monophosphate metabolic process 2.783111e-3
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 2.818370e-3
GO:0006006 glucose metabolic process 2.820675e-3
GO:0045005 maintenance of fidelity involved in DNA-dependent DNA replication 2.892646e-3
GO:0072111 cell proliferation involved in kidney development 2.920285e-3
GO:0009156 ribonucleoside monophosphate biosynthetic process 2.925510e-3
GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation 2.934032e-3
GO:0032066 nucleolus to nucleoplasm transport 2.934032e-3
GO:0045900 negative regulation of translational elongation 2.934032e-3
GO:0010720 positive regulation of cell development 2.987713e-3
GO:2000109 regulation of macrophage apoptosis 2.990402e-3
GO:0045944 positive regulation of transcription from RNA polymerase II promoter 3.029783e-3
GO:0050926 regulation of positive chemotaxis 3.038750e-3
GO:0007442 hindgut morphogenesis 3.076151e-3
GO:0022411 cellular component disassembly 3.144897e-3
GO:0031507 heterochromatin formation 3.179207e-3
GO:0042416 dopamine biosynthetic process 3.299813e-3
GO:0001894 tissue homeostasis 3.301354e-3
GO:0065001 specification of axis polarity 3.319274e-3
GO:0030644 cellular chloride ion homeostasis 3.319274e-3
GO:0006144 purine base metabolic process 3.330372e-3
GO:0071285 cellular response to lithium ion 3.330852e-3
GO:0090322 regulation of superoxide metabolic process 3.374041e-3
GO:0051318 G1 phase 3.376965e-3
GO:0010718 positive regulation of epithelial to mesenchymal transition 3.405241e-3
GO:0050793 regulation of developmental process 3.430950e-3
GO:0042074 cell migration involved in gastrulation 3.486404e-3
GO:0003406 retinal pigment epithelium development 3.493069e-3
GO:0060555 induction of necroptosis by extracellular signals 3.498841e-3
GO:0001763 morphogenesis of a branching structure 3.527335e-3
GO:0060334 regulation of interferon-gamma-mediated signaling pathway 3.573132e-3
GO:0045892 negative regulation of transcription, DNA-dependent 3.590116e-3
GO:0032148 activation of protein kinase B activity 3.683821e-3
GO:0006925 inflammatory cell apoptosis 3.684891e-3
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 3.721832e-3
GO:0051252 regulation of RNA metabolic process 3.767289e-3
GO:0090273 regulation of somatostatin secretion 3.769708e-3
GO:0055119 relaxation of cardiac muscle 3.769708e-3
GO:0030219 megakaryocyte differentiation 3.769708e-3
GO:0090276 regulation of peptide hormone secretion 3.822260e-3
GO:0008078 mesodermal cell migration 3.877533e-3
GO:0018130 heterocycle biosynthetic process 3.913590e-3
GO:0006415 translational termination 3.952666e-3
GO:0033599 regulation of mammary gland epithelial cell proliferation 3.964552e-3
GO:0030258 lipid modification 3.983065e-3
GO:0006071 glycerol metabolic process 4.040402e-3
GO:0072321 chaperone-mediated protein transport 4.076875e-3
GO:0040009 regulation of growth rate 4.112934e-3
GO:0051939 gamma-aminobutyric acid import 4.182612e-3
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 4.182612e-3
GO:0048871 multicellular organismal homeostasis 4.207583e-3
GO:0019058 viral infectious cycle 4.272234e-3
GO:0090343 positive regulation of cell aging 4.288431e-3
GO:0051896 regulation of protein kinase B signaling cascade 4.350883e-3
GO:0006885 regulation of pH 4.358537e-3
GO:0060323 head morphogenesis 4.401974e-3
GO:0007605 sensory perception of sound 4.419853e-3
GO:0016071 mRNA metabolic process 4.431439e-3
GO:0007411 axon guidance 4.561580e-3
GO:0019318 hexose metabolic process 4.580014e-3
GO:0021915 neural tube development 4.604407e-3
GO:0090003 regulation of establishment of protein localization in plasma membrane 4.640842e-3
GO:0090399 replicative senescence 4.684584e-3
GO:0019059 initiation of viral infection 4.711766e-3
GO:0031954 positive regulation of protein autophosphorylation 4.747048e-3
GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway 4.851085e-3
GO:0045746 negative regulation of Notch signaling pathway 4.862859e-3
GO:0045039 protein import into mitochondrial inner membrane 4.943364e-3
GO:0008625 induction of apoptosis via death domain receptors 4.944944e-3
GO:0072594 establishment of protein localization to organelle 4.974941e-3
GO:0010477 response to sulfur dioxide 4.989389e-3
GO:0002457 T cell antigen processing and presentation 4.989389e-3
GO:0055118 negative regulation of cardiac muscle contraction 5.021740e-3
GO:0051253 negative regulation of RNA metabolic process 5.157867e-3
GO:0051103 DNA ligation involved in DNA repair 5.177785e-3
GO:0002791 regulation of peptide secretion 5.241044e-3
GO:0033092 positive regulation of immature T cell proliferation in thymus 5.419527e-3
GO:0006366 transcription from RNA polymerase II promoter 5.495831e-3
GO:0042659 regulation of cell fate specification 5.511884e-3
GO:2000772 regulation of cellular senescence 5.576636e-3
GO:0051024 positive regulation of immunoglobulin secretion 5.746978e-3
GO:0043497 regulation of protein heterodimerization activity 5.812771e-3
GO:0010558 negative regulation of macromolecule biosynthetic process 5.829736e-3
GO:0000073 spindle pole body separation 5.861633e-3
GO:0035104 positive regulation of transcription via sterol regulatory element binding 5.925375e-3
GO:0070995 NADPH oxidation 5.940590e-3
GO:0034641 cellular nitrogen compound metabolic process 5.946478e-3
GO:0001958 endochondral ossification 6.070356e-3
GO:0051095 regulation of helicase activity 6.189674e-3
GO:0070972 protein localization in endoplasmic reticulum 6.333418e-3
GO:0006639 acylglycerol metabolic process 6.417692e-3
GO:0019227 neuronal action potential propagation 6.461684e-3
GO:0034284 response to monosaccharide stimulus 6.511795e-3
GO:0071346 cellular response to interferon-gamma 6.599815e-3
GO:0010717 regulation of epithelial to mesenchymal transition 6.628428e-3
GO:0043524 negative regulation of neuron apoptosis 6.723146e-3
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 6.741498e-3
GO:0030201 heparan sulfate proteoglycan metabolic process 6.777915e-3
GO:0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I 6.798107e-3
GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent 6.798107e-3
GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent 6.798107e-3
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent 6.798107e-3
GO:0034332 adherens junction organization 6.831915e-3
GO:2000278 regulation of DNA biosynthetic process 6.895185e-3
GO:0031327 negative regulation of cellular biosynthetic process 6.895757e-3
GO:0009167 purine ribonucleoside monophosphate metabolic process 6.921341e-3
GO:2000279 negative regulation of DNA biosynthetic process 6.968600e-3
GO:0009890 negative regulation of biosynthetic process 7.033962e-3
GO:0044249 cellular biosynthetic process 7.126368e-3
GO:0019400 alditol metabolic process 7.126678e-3
GO:0009168 purine ribonucleoside monophosphate biosynthetic process 7.170654e-3
GO:0048002 antigen processing and presentation of peptide antigen 7.258046e-3
GO:0042593 glucose homeostasis 7.340269e-3
GO:0072179 nephric duct formation 7.413169e-3
GO:0031325 positive regulation of cellular metabolic process 7.430493e-3
GO:0048522 positive regulation of cellular process 7.481413e-3
GO:0045923 positive regulation of fatty acid metabolic process 7.510124e-3
GO:0006369 termination of RNA polymerase II transcription 7.576394e-3
GO:0071777 positive regulation of cell cycle cytokinesis 7.642691e-3
GO:0072124 regulation of glomerular mesangial cell proliferation 7.642691e-3
GO:0006214 thymidine catabolic process 7.701490e-3
GO:0043000 Golgi to plasma membrane CFTR protein transport 7.797590e-3
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 7.865201e-3
GO:0048807 female genitalia morphogenesis 7.940626e-3
GO:0006919 activation of caspase activity 7.961382e-3
GO:0009084 glutamine family amino acid biosynthetic process 7.990738e-3
GO:0034623 cellular macromolecular complex disassembly 8.060292e-3
GO:0019369 arachidonic acid metabolic process 8.083589e-3
GO:0072164 mesonephric tubule development 8.083589e-3
GO:0035881 amacrine cell differentiation 8.184603e-3
GO:0001525 angiogenesis 8.219771e-3
GO:0035058 nonmotile primary cilium assembly 8.360825e-3
GO:0010604 positive regulation of macromolecule metabolic process 8.369151e-3
GO:0007155 cell adhesion 8.412869e-3
GO:0034260 negative regulation of GTPase activity 8.482331e-3
GO:0046849 bone remodeling 8.565743e-3
GO:0048598 embryonic morphogenesis 8.570392e-3
GO:0016051 carbohydrate biosynthetic process 8.659360e-3
GO:0045059 positive thymic T cell selection 8.686899e-3
GO:0034391 regulation of smooth muscle cell apoptosis 8.686899e-3
GO:0002456 T cell mediated immunity 8.686899e-3
GO:0006638 neutral lipid metabolic process 8.720764e-3
GO:0006641 triglyceride metabolic process 8.727361e-3
GO:0051607 defense response to virus 8.741570e-3
GO:0019433 triglyceride catabolic process 8.794762e-3
GO:0016337 cell-cell adhesion 8.798014e-3
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 8.848224e-3
GO:0006355 regulation of transcription, DNA-dependent 9.064092e-3
GO:0060662 salivary gland cavitation 9.124355e-3
GO:0009112 nucleobase metabolic process 9.197385e-3
GO:0016571 histone methylation 9.234736e-3
GO:0007509 mesoderm migration involved in gastrulation 9.271747e-3
GO:0060684 epithelial-mesenchymal cell signaling 9.321771e-3
GO:0007172 signal complex assembly 9.321771e-3
GO:0051154 negative regulation of striated muscle cell differentiation 9.389184e-3
GO:0030282 bone mineralization 9.446386e-3
GO:0030262 apoptotic nuclear change 9.446386e-3
GO:0031497 chromatin assembly 9.450699e-3
GO:0009743 response to carbohydrate stimulus 9.453558e-3
GO:0090288 negative regulation of cellular response to growth factor stimulus 9.659252e-3
GO:0042351 'de novo' GDP-L-fucose biosynthetic process 9.739093e-3
GO:0006212 uracil catabolic process 9.739093e-3
GO:0006210 thymine catabolic process 9.739093e-3
GO:0014031 mesenchymal cell development 9.760884e-3
GO:0008380 RNA splicing 9.764143e-3
GO:0051149 positive regulation of muscle cell differentiation 9.918751e-3
GO:0034405 response to fluid shear stress 9.927888e-3
GO:0006569 tryptophan catabolic process 9.964021e-3
GO:0043017 positive regulation of lymphotoxin A biosynthetic process 9.980791e-3
GO:0010085 polarity specification of proximal/distal axis 9.980791e-3
GO:0048793 pronephros development 1.021530e-2
GO:0001955 blood vessel maturation 1.021530e-2
GO:0006568 tryptophan metabolic process 1.035776e-2
GO:0051186 cofactor metabolic process 1.055353e-2
GO:0001569 patterning of blood vessels 1.057845e-2
GO:0032984 macromolecular complex disassembly 1.065019e-2
GO:0002666 positive regulation of T cell tolerance induction 1.079288e-2
GO:2000191 regulation of fatty acid transport 1.082600e-2
GO:0031214 biomineral tissue development 1.087097e-2
GO:0006333 chromatin assembly or disassembly 1.117263e-2
GO:0006351 transcription, DNA-dependent 1.118439e-2
GO:0021629 olfactory nerve structural organization 1.145376e-2
GO:0046825 regulation of protein export from nucleus 1.164325e-2
GO:0090208 positive regulation of triglyceride metabolic process 1.170041e-2
GO:0010171 body morphogenesis 1.173215e-2
GO:0048754 branching morphogenesis of a tube 1.176726e-2
GO:0032713 negative regulation of interleukin-4 production 1.182510e-2
GO:0032890 regulation of organic acid transport 1.188886e-2
GO:0055098 response to low-density lipoprotein particle stimulus 1.193332e-2
GO:0006807 nitrogen compound metabolic process 1.200921e-2
GO:0034505 tooth mineralization 1.204634e-2
GO:0046635 positive regulation of alpha-beta T cell activation 1.223217e-2
GO:0048015 phosphatidylinositol-mediated signaling 1.224797e-2
GO:0046464 acylglycerol catabolic process 1.224904e-2
GO:0031175 neuron projection development 1.225276e-2
GO:0046341 CDP-diacylglycerol metabolic process 1.240181e-2
GO:0044335 canonical Wnt receptor signaling pathway involved in neural crest cell differentiation 1.240181e-2
GO:0048643 positive regulation of skeletal muscle tissue development 1.246389e-2
GO:0009058 biosynthetic process 1.252760e-2
GO:0050848 regulation of calcium-mediated signaling 1.253382e-2
GO:0010660 regulation of muscle cell apoptosis 1.258341e-2
GO:0019859 thymine metabolic process 1.268719e-2
GO:0006625 protein targeting to peroxisome 1.272657e-2
GO:0010940 positive regulation of necrotic cell death 1.277611e-2
GO:0050870 positive regulation of T cell activation 1.319013e-2
GO:0006729 tetrahydrobiopterin biosynthetic process 1.321074e-2
GO:0060021 palate development 1.324442e-2
GO:0010629 negative regulation of gene expression 1.324485e-2
GO:0033600 negative regulation of mammary gland epithelial cell proliferation 1.332576e-2
GO:0000904 cell morphogenesis involved in differentiation 1.348317e-2
GO:0006662 glycerol ether metabolic process 1.364105e-2
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 1.369862e-2
GO:0034645 cellular macromolecule biosynthetic process 1.371158e-2
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 1.378569e-2
GO:0002070 epithelial cell maturation 1.392490e-2
GO:0032933 SREBP-mediated signaling pathway 1.412955e-2
GO:0071396 cellular response to lipid 1.432543e-2
GO:0060466 activation of meiosis involved in egg activation 1.467441e-2
GO:0006284 base-excision repair 1.469609e-2
GO:0060795 cell fate commitment involved in formation of primary germ layers 1.477569e-2
GO:2000112 regulation of cellular macromolecule biosynthetic process 1.487469e-2
GO:0032653 regulation of interleukin-10 production 1.488337e-2
GO:2000179 positive regulation of neural precursor cell proliferation 1.488337e-2
GO:0007409 axonogenesis 1.492691e-2
GO:0051171 regulation of nitrogen compound metabolic process 1.499691e-2
GO:0043574 peroxisomal transport 1.502115e-2
GO:2000344 positive regulation of acrosome reaction 1.504285e-2
GO:0042666 negative regulation of ectodermal cell fate specification 1.505147e-2
GO:0006145 purine base catabolic process 1.537362e-2
GO:0030838 positive regulation of actin filament polymerization 1.551728e-2
GO:0000723 telomere maintenance 1.562624e-2
GO:0050954 sensory perception of mechanical stimulus 1.573823e-2
GO:0048646 anatomical structure formation involved in morphogenesis 1.576559e-2
GO:0035814 negative regulation of renal sodium excretion 1.601591e-2
GO:0051153 regulation of striated muscle cell differentiation 1.614986e-2
GO:0046112 nucleobase biosynthetic process 1.626960e-2
GO:0051239 regulation of multicellular organismal process 1.629596e-2
GO:0060044 negative regulation of cardiac muscle cell proliferation 1.651690e-2
GO:0046887 positive regulation of hormone secretion 1.657059e-2
GO:0060986 endocrine hormone secretion 1.659255e-2
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 1.682757e-2
GO:0046104 thymidine metabolic process 1.682757e-2
GO:0006196 AMP catabolic process 1.682757e-2
GO:0046146 tetrahydrobiopterin metabolic process 1.702758e-2
GO:0009059 macromolecule biosynthetic process 1.717292e-2
GO:0048812 neuron projection morphogenesis 1.748192e-2
GO:2000369 regulation of clathrin-mediated endocytosis 1.758238e-2
GO:0001957 intramembranous ossification 1.770129e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 7.456868e-14
GO:0035912 dorsal aorta morphogenesis 1.215436e-11
GO:0030038 contractile actin filament bundle assembly 1.215436e-11
GO:0010735 positive regulation of transcription via serum response element binding 4.380530e-10
GO:0033561 regulation of water loss via skin 8.470993e-10
GO:0001947 heart looping 1.203516e-9
GO:0009952 anterior/posterior pattern specification 1.334835e-9
GO:0032367 intracellular cholesterol transport 1.494682e-9
GO:0009948 anterior/posterior axis specification 3.026831e-9
GO:0032078 negative regulation of endodeoxyribonuclease activity 3.903155e-9
GO:0006922 cleavage of lamin 3.903155e-9
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 4.534695e-9
GO:0090009 primitive streak formation 5.326569e-9
GO:2000142 regulation of transcription initiation, DNA-dependent 5.861916e-9
GO:0032365 intracellular lipid transport 6.784613e-9
GO:0035050 embryonic heart tube development 7.486455e-9
GO:0016226 iron-sulfur cluster assembly 9.800665e-9
GO:0001704 formation of primary germ layer 1.100450e-8
GO:0042663 regulation of endodermal cell fate specification 1.188939e-8
GO:0007369 gastrulation 1.211287e-8
GO:0001711 endodermal cell fate commitment 2.584023e-8
GO:0001763 morphogenesis of a branching structure 2.760055e-8
GO:0055013 cardiac muscle cell development 4.282045e-8
GO:0010669 epithelial structure maintenance 4.423929e-8
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway 5.763376e-8
GO:0060947 cardiac vascular smooth muscle cell differentiation 6.766397e-8
GO:0032074 negative regulation of nuclease activity 8.940276e-8
GO:0002541 activation of plasma proteins involved in acute inflammatory response 8.940276e-8
GO:0055006 cardiac cell development 8.984188e-8
GO:0003002 regionalization 1.030646e-7
GO:0048332 mesoderm morphogenesis 1.167761e-7
GO:0032071 regulation of endodeoxyribonuclease activity 1.291829e-7
GO:0035907 dorsal aorta development 1.480436e-7
GO:0060218 hemopoietic stem cell differentiation 1.704137e-7
GO:0035855 megakaryocyte development 1.955660e-7
GO:0035987 endodermal cell differentiation 2.037021e-7
GO:0055098 response to low-density lipoprotein particle stimulus 2.415538e-7
GO:0060795 cell fate commitment involved in formation of primary germ layers 3.024491e-7
GO:0032070 regulation of deoxyribonuclease activity 3.371409e-7
GO:2000121 regulation of removal of superoxide radicals 4.216744e-7
GO:0035909 aorta morphogenesis 4.928872e-7
GO:0007368 determination of left/right symmetry 5.124333e-7
GO:0035590 purinergic nucleotide receptor signaling pathway 5.157907e-7
GO:0048754 branching morphogenesis of a tube 5.684963e-7
GO:0039020 pronephric nephron tubule development 5.822482e-7
GO:0035565 regulation of pronephros size 5.822482e-7
GO:0009799 specification of symmetry 7.192697e-7
GO:0007569 cell aging 7.313373e-7
GO:0072181 mesonephric duct formation 7.485349e-7
GO:0035588 G-protein coupled purinergic receptor signaling pathway 8.742702e-7
GO:0007498 mesoderm development 8.760181e-7
GO:0035282 segmentation 9.114188e-7
GO:0009082 branched chain family amino acid biosynthetic process 1.575832e-6
GO:0021761 limbic system development 1.662136e-6
GO:0060931 sinoatrial node cell development 1.799973e-6
GO:0003167 atrioventricular bundle cell differentiation 1.799973e-6
GO:0022028 tangential migration from the subventricular zone to the olfactory bulb 2.032313e-6
GO:0002042 cell migration involved in sprouting angiogenesis 2.073489e-6
GO:0035904 aorta development 2.132876e-6
GO:0035886 vascular smooth muscle cell differentiation 2.427353e-6
GO:0007389 pattern specification process 2.539330e-6
GO:0055094 response to lipoprotein stimulus 2.721776e-6
GO:0008595 anterior/posterior axis specification, embryo 3.129874e-6
GO:0009798 axis specification 3.283485e-6
GO:0060921 sinoatrial node cell differentiation 3.756460e-6
GO:0007141 male meiosis I 3.827726e-6
GO:0021988 olfactory lobe development 3.939780e-6
GO:0070830 tight junction assembly 4.131266e-6
GO:0003151 outflow tract morphogenesis 4.296811e-6
GO:0038007 netrin-activated signaling pathway 4.551057e-6
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 4.551057e-6
GO:0035587 purinergic receptor signaling pathway 4.617211e-6
GO:0060932 His-Purkinje system cell differentiation 4.701455e-6
GO:0060926 pacemaker cell development 4.701455e-6
GO:0006437 tyrosyl-tRNA aminoacylation 5.101834e-6
GO:0055007 cardiac muscle cell differentiation 5.365698e-6
GO:0046884 follicle-stimulating hormone secretion 5.830981e-6
GO:0032275 luteinizing hormone secretion 5.830981e-6
GO:0061138 morphogenesis of a branching epithelium 5.998560e-6
GO:0061017 hepatoblast differentiation 6.273734e-6
GO:0048806 genitalia development 6.290556e-6
GO:0001714 endodermal cell fate specification 6.709423e-6
GO:0003163 sinoatrial node development 7.929345e-6
GO:0060920 pacemaker cell differentiation 8.751028e-6
GO:0060976 coronary vasculature development 1.058151e-5
GO:0001825 blastocyst formation 1.097593e-5
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process 1.156461e-5
GO:0060537 muscle tissue development 1.339260e-5
GO:0090136 epithelial cell-cell adhesion 1.376939e-5
GO:0010159 specification of organ position 1.525093e-5
GO:0002011 morphogenesis of an epithelial sheet 1.584209e-5
GO:0021772 olfactory bulb development 1.719056e-5
GO:0042659 regulation of cell fate specification 1.731421e-5
GO:0048821 erythrocyte development 1.785087e-5
GO:0035564 regulation of kidney size 1.812565e-5
GO:0048646 anatomical structure formation involved in morphogenesis 1.829787e-5
GO:0007568 aging 2.130895e-5
GO:0090398 cellular senescence 2.299526e-5
GO:0060292 long term synaptic depression 2.309098e-5
GO:0050891 multicellular organismal water homeostasis 2.309098e-5
GO:0003206 cardiac chamber morphogenesis 2.338665e-5
GO:0048863 stem cell differentiation 2.399864e-5
GO:0003309 type B pancreatic cell differentiation 2.940986e-5
GO:0060923 cardiac muscle cell fate commitment 2.946050e-5
GO:0034626 fatty acid elongation, polyunsaturated fatty acid 2.946050e-5
GO:0034625 fatty acid elongation, monounsaturated fatty acid 3.180702e-5
GO:0035239 tube morphogenesis 3.184453e-5
GO:0060347 heart trabecula formation 3.306541e-5
GO:0030219 megakaryocyte differentiation 3.306541e-5
GO:0048738 cardiac muscle tissue development 3.507606e-5
GO:0061384 heart trabecular morphogenesis 3.536587e-5
GO:0001826 inner cell mass cell differentiation 3.697719e-5
GO:2000379 positive regulation of reactive oxygen species metabolic process 3.884013e-5
GO:0031018 endocrine pancreas development 4.416399e-5
GO:0072180 mesonephric duct morphogenesis 4.536694e-5
GO:0001706 endoderm formation 4.808263e-5
GO:0001756 somitogenesis 5.895505e-5
GO:0043297 apical junction assembly 6.034684e-5
GO:0060907 positive regulation of macrophage cytokine production 6.047153e-5
GO:0010453 regulation of cell fate commitment 6.171004e-5
GO:0030539 male genitalia development 6.564406e-5
GO:0055003 cardiac myofibril assembly 6.614037e-5
GO:0090322 regulation of superoxide metabolic process 6.703153e-5
GO:0014706 striated muscle tissue development 7.111359e-5
GO:0003205 cardiac chamber development 7.545885e-5
GO:0003166 bundle of His development 7.842515e-5
GO:0072095 regulation of branch elongation involved in ureteric bud branching 7.956489e-5
GO:0060688 regulation of morphogenesis of a branching structure 8.117990e-5
GO:2000334 positive regulation of blood microparticle formation 8.123282e-5
GO:0046546 development of primary male sexual characteristics 8.124292e-5
GO:0055001 muscle cell development 8.160559e-5
GO:0001702 gastrulation with mouth forming second 8.385125e-5
GO:0007140 male meiosis 8.748924e-5
GO:0060444 branching involved in mammary gland duct morphogenesis 9.080849e-5
GO:0048729 tissue morphogenesis 9.203067e-5
GO:0060677 ureteric bud elongation 9.451684e-5
GO:0060411 cardiac septum morphogenesis 9.910317e-5
GO:0010470 regulation of gastrulation 9.949128e-5
GO:0045766 positive regulation of angiogenesis 1.164251e-4
GO:0019368 fatty acid elongation, unsaturated fatty acid 1.271282e-4
GO:0034551 mitochondrial respiratory chain complex III assembly 1.359544e-4
GO:0021750 vestibular nucleus development 1.364581e-4
GO:0021679 cerebellar molecular layer development 1.364581e-4
GO:0021590 cerebellum maturation 1.364581e-4
GO:0046716 muscle cell homeostasis 1.387204e-4
GO:0060005 vestibular reflex 1.413587e-4
GO:0003350 pulmonary myocardium development 1.413587e-4
GO:0032908 regulation of transforming growth factor beta1 production 1.424204e-4
GO:0010817 regulation of hormone levels 1.429198e-4
GO:0000578 embryonic axis specification 1.437859e-4
GO:0007254 JNK cascade 1.509434e-4
GO:0032069 regulation of nuclease activity 1.525415e-4
GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 1.564798e-4
GO:0060911 cardiac cell fate commitment 1.591329e-4
GO:0045987 positive regulation of smooth muscle contraction 1.634124e-4
GO:0035051 cardiac cell differentiation 1.674160e-4
GO:0046879 hormone secretion 1.697281e-4
GO:0071447 cellular response to hydroperoxide 1.724149e-4
GO:0015911 plasma membrane long-chain fatty acid transport 1.724149e-4
GO:0072172 mesonephric tubule formation 1.769236e-4
GO:0009083 branched chain family amino acid catabolic process 1.773585e-4
GO:0001707 mesoderm formation 1.805781e-4
GO:0030220 platelet formation 1.857144e-4
GO:0023061 signal release 1.858800e-4
GO:0043000 Golgi to plasma membrane CFTR protein transport 1.893368e-4
GO:0050883 musculoskeletal movement, spinal reflex action 1.927455e-4
GO:0060414 aorta smooth muscle tissue morphogenesis 2.041703e-4
GO:0044283 small molecule biosynthetic process 2.149963e-4
GO:0035117 embryonic arm morphogenesis 2.187363e-4
GO:0060100 positive regulation of phagocytosis, engulfment 2.385024e-4
GO:0046661 male sex differentiation 2.531039e-4
GO:0046902 regulation of mitochondrial membrane permeability 2.574086e-4
GO:0010935 regulation of macrophage cytokine production 2.677487e-4
GO:0021766 hippocampus development 2.730154e-4
GO:0048793 pronephros development 2.862671e-4
GO:0043149 stress fiber assembly 2.894301e-4
GO:0021578 hindbrain maturation 2.915854e-4
GO:0051146 striated muscle cell differentiation 3.021660e-4
GO:0060841 venous blood vessel development 3.124989e-4
GO:2000108 positive regulation of leukocyte apoptosis 3.166517e-4
GO:0007492 endoderm development 3.252782e-4
GO:0042574 retinal metabolic process 3.253014e-4
GO:0030104 water homeostasis 3.370194e-4
GO:0032912 negative regulation of transforming growth factor beta2 production 3.526434e-4
GO:0071542 dopaminergic neuron differentiation 3.682345e-4
GO:0061053 somite development 3.708791e-4
GO:0042761 very long-chain fatty acid biosynthetic process 3.898456e-4
GO:0060004 reflex 3.976547e-4
GO:0031098 stress-activated protein kinase signaling cascade 4.053076e-4
GO:0016567 protein ubiquitination 4.137705e-4
GO:0009880 embryonic pattern specification 4.215681e-4
GO:0002009 morphogenesis of an epithelium 4.249162e-4
GO:0032755 positive regulation of interleukin-6 production 4.479652e-4
GO:0014056 regulation of acetylcholine secretion 4.606273e-4
GO:0072177 mesonephric duct development 4.667947e-4
GO:0051603 proteolysis involved in cellular protein catabolic process 4.691261e-4
GO:0040007 growth 4.760712e-4
GO:0072171 mesonephric tubule morphogenesis 5.229349e-4
GO:2000648 positive regulation of stem cell proliferation 5.295336e-4
GO:0008340 determination of adult lifespan 5.365048e-4
GO:0043503 skeletal muscle fiber adaptation 5.445243e-4
GO:0060638 mesenchymal-epithelial cell signaling 5.550655e-4
GO:0030239 myofibril assembly 5.650216e-4
GO:0072091 regulation of stem cell proliferation 5.741330e-4
GO:0002040 sprouting angiogenesis 5.843486e-4
GO:0060562 epithelial tube morphogenesis 5.932975e-4
GO:0003161 cardiac conduction system development 6.001152e-4
GO:0002779 antibacterial peptide secretion 6.244548e-4
GO:0050434 positive regulation of viral transcription 6.344752e-4
GO:0048852 diencephalon morphogenesis 6.502601e-4
GO:0060596 mammary placode formation 6.510766e-4
GO:0055096 low-density lipoprotein particle mediated signaling 6.899249e-4
GO:0031334 positive regulation of protein complex assembly 6.935047e-4
GO:0002720 positive regulation of cytokine production involved in immune response 7.002553e-4
GO:0030163 protein catabolic process 7.084560e-4
GO:0044257 cellular protein catabolic process 7.215050e-4
GO:0072179 nephric duct formation 7.219902e-4
GO:0061029 eyelid development in camera-type eye 7.226366e-4
GO:0001569 patterning of blood vessels 7.233250e-4
GO:0030497 fatty acid elongation 7.337280e-4
GO:0060788 ectodermal placode formation 8.068031e-4
GO:0006950 response to stress 8.407329e-4
GO:0060024 rhythmic synaptic transmission 8.608413e-4
GO:0048791 calcium ion-dependent exocytosis of neurotransmitter 8.829837e-4
GO:0031327 negative regulation of cellular biosynthetic process 8.904648e-4
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 9.012802e-4
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 9.012802e-4
GO:0000027 ribosomal large subunit assembly 9.317260e-4
GO:0016574 histone ubiquitination 9.470102e-4
GO:0045662 negative regulation of myoblast differentiation 9.857775e-4
GO:0070997 neuron death 9.857942e-4
GO:0060603 mammary gland duct morphogenesis 9.896460e-4
GO:0007493 endodermal cell fate determination 1.059591e-3
GO:0003279 cardiac septum development 1.078245e-3
GO:0009914 hormone transport 1.091276e-3
GO:0006633 fatty acid biosynthetic process 1.092542e-3
GO:0045165 cell fate commitment 1.097275e-3
GO:0009887 organ morphogenesis 1.127285e-3
GO:0006839 mitochondrial transport 1.205740e-3
GO:0071221 cellular response to bacterial lipopeptide 1.208698e-3
GO:0060437 lung growth 1.208698e-3
GO:0003148 outflow tract septum morphogenesis 1.231777e-3
GO:0061061 muscle structure development 1.277682e-3
GO:0007076 mitotic chromosome condensation 1.283194e-3
GO:0009890 negative regulation of biosynthetic process 1.305231e-3
GO:0003007 heart morphogenesis 1.317017e-3
GO:0007267 cell-cell signaling 1.336880e-3
GO:0031032 actomyosin structure organization 1.338147e-3
GO:0007548 sex differentiation 1.379690e-3
GO:0043534 blood vessel endothelial cell migration 1.395420e-3
GO:0046394 carboxylic acid biosynthetic process 1.407519e-3
GO:0048813 dendrite morphogenesis 1.422668e-3
GO:0051491 positive regulation of filopodium assembly 1.474569e-3
GO:0032446 protein modification by small protein conjugation 1.493250e-3
GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 1.579650e-3
GO:0033344 cholesterol efflux 1.617355e-3
GO:0009615 response to virus 1.643795e-3
GO:0050881 musculoskeletal movement 1.682389e-3
GO:0007043 cell-cell junction assembly 1.721314e-3
GO:0032911 negative regulation of transforming growth factor beta1 production 1.743270e-3
GO:0045785 positive regulation of cell adhesion 1.799646e-3
GO:0042472 inner ear morphogenesis 1.802327e-3
GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 1.803609e-3
GO:0007628 adult walking behavior 1.836024e-3
GO:0007006 mitochondrial membrane organization 1.836024e-3
GO:0014051 gamma-aminobutyric acid secretion 1.845981e-3
GO:0032274 gonadotropin secretion 1.894233e-3
GO:0051145 smooth muscle cell differentiation 1.938684e-3
GO:0051253 negative regulation of RNA metabolic process 2.012181e-3
GO:0061383 trabecula morphogenesis 2.052347e-3
GO:0051025 negative regulation of immunoglobulin secretion 2.200880e-3
GO:0009081 branched chain family amino acid metabolic process 2.210235e-3
GO:0045022 early endosome to late endosome transport 2.284612e-3
GO:0001829 trophectodermal cell differentiation 2.301505e-3
GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 2.303562e-3
GO:0017004 cytochrome complex assembly 2.303562e-3
GO:0010811 positive regulation of cell-substrate adhesion 2.362818e-3
GO:0051354 negative regulation of oxidoreductase activity 2.373020e-3
GO:0071404 cellular response to low-density lipoprotein particle stimulus 2.422924e-3
GO:0042060 wound healing 2.505087e-3
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent 2.511615e-3
GO:0030644 cellular chloride ion homeostasis 2.551568e-3
GO:0072078 nephron tubule morphogenesis 2.602224e-3
GO:0072178 nephric duct morphogenesis 2.653154e-3
GO:0010558 negative regulation of macromolecule biosynthetic process 2.654499e-3
GO:0030301 cholesterol transport 2.658042e-3
GO:0030193 regulation of blood coagulation 2.721332e-3
GO:0046782 regulation of viral transcription 2.730612e-3
GO:0035295 tube development 2.743105e-3
GO:0006511 ubiquitin-dependent protein catabolic process 2.749917e-3
GO:0030534 adult behavior 2.786536e-3
GO:0060412 ventricular septum morphogenesis 2.812108e-3
GO:2000113 negative regulation of cellular macromolecule biosynthetic process 2.812964e-3
GO:0045995 regulation of embryonic development 2.857834e-3
GO:0019835 cytolysis 2.877102e-3
GO:0009791 post-embryonic development 2.930505e-3
GO:0030194 positive regulation of blood coagulation 2.932236e-3
GO:0031175 neuron projection development 2.946790e-3
GO:0061350 planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 2.961658e-3
GO:0060210 metestrus 2.961658e-3
GO:0061349 planar cell polarity pathway involved in cardiac right atrium morphogenesis 2.961658e-3
GO:0061354 planar cell polarity pathway involved in pericardium morphogenesis 2.961658e-3
GO:0061348 planar cell polarity pathway involved in ventricular septum morphogenesis 2.961658e-3
GO:0061347 planar cell polarity pathway involved in outflow tract morphogenesis 2.961658e-3
GO:0042904 9-cis-retinoic acid biosynthetic process 2.965476e-3
GO:0051402 neuron apoptosis 3.009044e-3
GO:0071634 regulation of transforming growth factor beta production 3.072849e-3
GO:0051188 cofactor biosynthetic process 3.110908e-3
GO:0070245 positive regulation of thymocyte apoptosis 3.129697e-3
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin 3.204032e-3
GO:0071402 cellular response to lipoprotein particle stimulus 3.265526e-3
GO:0071223 cellular response to lipoteichoic acid 3.265526e-3
GO:0032909 regulation of transforming growth factor beta2 production 3.284077e-3
GO:0021952 central nervous system projection neuron axonogenesis 3.293357e-3
GO:0019941 modification-dependent protein catabolic process 3.303998e-3
GO:0060343 trabecula formation 3.325544e-3
GO:0043254 regulation of protein complex assembly 3.366117e-3
GO:0021543 pallium development 3.404593e-3
GO:0048145 regulation of fibroblast proliferation 3.422845e-3
GO:0030320 cellular monovalent inorganic anion homeostasis 3.423021e-3
GO:0043632 modification-dependent macromolecule catabolic process 3.425555e-3
GO:0061041 regulation of wound healing 3.456923e-3
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 3.488849e-3
GO:0045059 positive thymic T cell selection 3.525728e-3
GO:0000209 protein polyubiquitination 3.537301e-3
GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation 3.585600e-3
GO:0032353 negative regulation of hormone biosynthetic process 3.585600e-3
GO:0070234 positive regulation of T cell apoptosis 3.684041e-3
GO:0007616 long-term memory 3.687432e-3
GO:0070848 response to growth factor stimulus 3.722375e-3
GO:0060067 cervix development 3.724398e-3
GO:0045892 negative regulation of transcription, DNA-dependent 3.786216e-3
GO:0010498 proteasomal protein catabolic process 3.864483e-3
GO:0072176 nephric duct development 3.886865e-3
GO:0022603 regulation of anatomical structure morphogenesis 3.923395e-3
GO:0051489 regulation of filopodium assembly 3.940473e-3
GO:0006104 succinyl-CoA metabolic process 3.971447e-3
GO:0002826 negative regulation of T-helper 1 type immune response 3.971447e-3
GO:2000377 regulation of reactive oxygen species metabolic process 4.040208e-3
GO:0043524 negative regulation of neuron apoptosis 4.048390e-3
GO:0015812 gamma-aminobutyric acid transport 4.104603e-3
GO:0007005 mitochondrion organization 4.179569e-3
GO:0048598 embryonic morphogenesis 4.234224e-3
GO:0060415 muscle tissue morphogenesis 4.272688e-3
GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis 4.293392e-3
GO:0045040 protein import into mitochondrial outer membrane 4.293392e-3
GO:0002553 histamine secretion by mast cell 4.293392e-3
GO:0002741 positive regulation of cytokine secretion involved in immune response 4.293392e-3
GO:0048147 negative regulation of fibroblast proliferation 4.308075e-3
GO:0045933 positive regulation of muscle contraction 4.581965e-3
GO:0071635 negative regulation of transforming growth factor beta production 4.672086e-3
GO:0031324 negative regulation of cellular metabolic process 4.690840e-3
GO:0072164 mesonephric tubule development 4.709971e-3
GO:0055002 striated muscle cell development 4.719256e-3
GO:0001824 blastocyst development 4.784493e-3
GO:0007257 activation of JUN kinase activity 4.801491e-3
GO:0060743 epithelial cell maturation involved in prostate gland development 4.912288e-3
GO:0045014 negative regulation of transcription by glucose 4.912288e-3
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 4.962727e-3
GO:0048853 forebrain morphogenesis 5.009872e-3
GO:0030240 skeletal muscle thin filament assembly 5.009872e-3
GO:0048644 muscle organ morphogenesis 5.023643e-3
GO:0033554 cellular response to stress 5.082496e-3
GO:0030073 insulin secretion 5.219299e-3
GO:0002790 peptide secretion 5.345108e-3
GO:0009607 response to biotic stimulus 5.371506e-3
GO:0060560 developmental growth involved in morphogenesis 5.397675e-3
GO:0032472 Golgi calcium ion transport 5.418276e-3
GO:0032468 Golgi calcium ion homeostasis 5.418276e-3
GO:0030026 cellular manganese ion homeostasis 5.418276e-3
GO:0007032 endosome organization 5.516625e-3
GO:0043589 skin morphogenesis 5.518779e-3
GO:0042471 ear morphogenesis 5.567771e-3
GO:0048850 hypophysis morphogenesis 5.582263e-3
GO:0030540 female genitalia development 5.649790e-3
GO:0045765 regulation of angiogenesis 5.653860e-3
GO:0042362 fat-soluble vitamin biosynthetic process 5.960337e-3
GO:0030825 positive regulation of cGMP metabolic process 5.960337e-3
GO:0050820 positive regulation of coagulation 6.218460e-3
GO:0048468 cell development 6.257316e-3
GO:0034261 negative regulation of Ras GTPase activity 6.304399e-3
GO:0043032 positive regulation of macrophage activation 6.345309e-3
GO:0051172 negative regulation of nitrogen compound metabolic process 6.379581e-3
GO:0071158 positive regulation of cell cycle arrest 6.465751e-3
GO:0070232 regulation of T cell apoptosis 6.465751e-3
GO:0045214 sarcomere organization 6.483410e-3
GO:0030155 regulation of cell adhesion 6.581788e-3
GO:0048524 positive regulation of viral reproduction 6.651513e-3
GO:0060751 branch elongation involved in mammary gland duct branching 6.684869e-3
GO:0045216 cell-cell junction organization 6.745910e-3
GO:0044265 cellular macromolecule catabolic process 6.755355e-3
GO:0050818 regulation of coagulation 6.865289e-3
GO:0060592 mammary gland formation 6.955954e-3
GO:0021889 olfactory bulb interneuron differentiation 6.955954e-3
GO:0035695 mitochondrion degradation by induced vacuole formation 7.070043e-3
GO:0002309 T cell proliferation involved in immune response 7.079682e-3
GO:0046463 acylglycerol biosynthetic process 7.098739e-3
GO:0044249 cellular biosynthetic process 7.230463e-3
GO:0055088 lipid homeostasis 7.264506e-3
GO:0045137 development of primary sexual characteristics 7.354459e-3
GO:0034599 cellular response to oxidative stress 7.422480e-3
GO:0048844 artery morphogenesis 7.442002e-3
GO:0003310 pancreatic A cell differentiation 7.465399e-3
GO:0090403 oxidative stress-induced premature senescence 7.487539e-3
GO:0022029 telencephalon cell migration 7.639790e-3
GO:0060548 negative regulation of cell death 7.700471e-3
GO:0033630 positive regulation of cell adhesion mediated by integrin 7.738316e-3
GO:0051707 response to other organism 7.805481e-3
GO:2000484 positive regulation of interleukin-8 secretion 7.909014e-3
GO:0003344 pericardium morphogenesis 7.909014e-3
GO:0060986 endocrine hormone secretion 7.939945e-3
GO:0019244 lactate biosynthetic process from pyruvate 7.969741e-3
GO:0021990 neural plate formation 7.969741e-3
GO:0002003 angiotensin maturation 7.970630e-3
GO:0000415 negative regulation of histone H3-K36 methylation 7.970630e-3
GO:0048589 developmental growth 8.002433e-3
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 8.017707e-3
GO:0021548 pons development 8.017707e-3
GO:0001568 blood vessel development 8.113337e-3
GO:0031398 positive regulation of protein ubiquitination 8.200551e-3
GO:0030168 platelet activation 8.230687e-3
GO:0007263 nitric oxide mediated signal transduction 8.303632e-3
GO:0060340 positive regulation of type I interferon-mediated signaling pathway 8.344205e-3
GO:0060840 artery development 8.359276e-3
GO:0009110 vitamin biosynthetic process 8.467755e-3
GO:0090189 regulation of branching involved in ureteric bud morphogenesis 8.559853e-3
GO:0042573 retinoic acid metabolic process 8.563678e-3
GO:2000106 regulation of leukocyte apoptosis 8.792881e-3
GO:0010458 exit from mitosis 8.793207e-3
GO:0000733 DNA strand renaturation 8.793207e-3
GO:0002702 positive regulation of production of molecular mediator of immune response 8.907396e-3
GO:0060575 intestinal epithelial cell differentiation 9.017852e-3
GO:0021537 telencephalon development 9.040620e-3
GO:0048752 semicircular canal morphogenesis 9.488366e-3
GO:0090037 positive regulation of protein kinase C signaling cascade 9.732993e-3
GO:0021885 forebrain cell migration 9.748911e-3
GO:0035115 embryonic forelimb morphogenesis 9.773283e-3
GO:0000038 very long-chain fatty acid metabolic process 9.861400e-3
GO:0046504 glycerol ether biosynthetic process 9.975492e-3
GO:0042221 response to chemical stimulus 1.005234e-2
GO:0010927 cellular component assembly involved in morphogenesis 1.005520e-2
GO:0048286 lung alveolus development 1.021931e-2
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 1.022394e-2
GO:0051890 regulation of cardioblast differentiation 1.022537e-2
GO:0014866 skeletal myofibril assembly 1.047950e-2
GO:0007127 meiosis I 1.078164e-2
GO:0042992 negative regulation of transcription factor import into nucleus 1.083186e-2
GO:0070171 negative regulation of tooth mineralization 1.096113e-2
GO:0044268 multicellular organismal protein metabolic process 1.096113e-2
GO:0007420 brain development 1.100590e-2
GO:0070243 regulation of thymocyte apoptosis 1.104790e-2
GO:0051930 regulation of sensory perception of pain 1.126773e-2
GO:0010820 positive regulation of T cell chemotaxis 1.153486e-2
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 1.171425e-2
GO:0043069 negative regulation of programmed cell death 1.175071e-2
GO:0046015 regulation of transcription by glucose 1.178188e-2
GO:0008333 endosome to lysosome transport 1.181507e-2
GO:2000406 positive regulation of T cell migration 1.189637e-2
GO:0021930 cerebellar granule cell precursor proliferation 1.205147e-2
GO:0032675 regulation of interleukin-6 production 1.222401e-2
GO:0043542 endothelial cell migration 1.229630e-2
GO:0043066 negative regulation of apoptosis 1.230852e-2
GO:0045658 regulation of neutrophil differentiation 1.232977e-2
GO:0050805 negative regulation of synaptic transmission 1.256614e-2
GO:0030857 negative regulation of epithelial cell differentiation 1.264608e-2
GO:0001894 tissue homeostasis 1.267683e-2
GO:0043506 regulation of JUN kinase activity 1.268709e-2
GO:0022612 gland morphogenesis 1.270489e-2
GO:0001954 positive regulation of cell-matrix adhesion 1.288693e-2
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling 1.302420e-2
GO:0043501 skeletal muscle adaptation 1.302420e-2
GO:0009058 biosynthetic process 1.310365e-2
GO:0035249 synaptic transmission, glutamatergic 1.313096e-2
GO:0060443 mammary gland morphogenesis 1.326044e-2
GO:0072079 nephron tubule formation 1.326175e-2
GO:0060693 regulation of branching involved in salivary gland morphogenesis 1.326175e-2
GO:0001938 positive regulation of endothelial cell proliferation 1.330045e-2
GO:0006952 defense response 1.330218e-2
GO:0070170 regulation of tooth mineralization 1.346877e-2
GO:0003323 type B pancreatic cell development 1.346877e-2
GO:0007034 vacuolar transport 1.373891e-2
GO:0060425 lung morphogenesis 1.394735e-2
GO:0060686 negative regulation of prostatic bud formation 1.405998e-2
GO:0002483 antigen processing and presentation of endogenous peptide antigen 1.405998e-2
GO:0072028 nephron morphogenesis 1.406562e-2
GO:0043405 regulation of MAP kinase activity 1.406944e-2
GO:0019432 triglyceride biosynthetic process 1.421794e-2
GO:0021986 habenula development 1.436760e-2
GO:0000414 regulation of histone H3-K36 methylation 1.436760e-2
GO:0006626 protein targeting to mitochondrion 1.439977e-2
GO:0007596 blood coagulation 1.445613e-2
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 1.450165e-2
GO:0007417 central nervous system development 1.462013e-2
GO:0051964 negative regulation of synapse assembly 1.466572e-2
GO:0051925 regulation of calcium ion transport via voltage-gated calcium channel activity 1.467586e-2
GO:0070647 protein modification by small protein conjugation or removal 1.479806e-2
GO:0007599 hemostasis 1.521937e-2
GO:0034260 negative regulation of GTPase activity 1.528603e-2
GO:0006379 mRNA cleavage 1.528603e-2
GO:0010259 multicellular organismal aging 1.548104e-2