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Novel motif:92

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name:motif92_GCGKWWNAA

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0019058 viral infectious cycle 2.188171e-16
GO:0071156 regulation of cell cycle arrest 1.129977e-14
GO:0000075 cell cycle checkpoint 3.326130e-13
GO:0022415 viral reproductive process 1.565818e-12
GO:0006414 translational elongation 1.755536e-12
GO:0019083 viral transcription 2.059186e-12
GO:0006415 translational termination 9.854023e-12
GO:0034623 cellular macromolecular complex disassembly 1.909819e-11
GO:0071845 cellular component disassembly at cellular level 2.828610e-11
GO:0022411 cellular component disassembly 7.994682e-11
GO:0032984 macromolecular complex disassembly 9.133804e-11
GO:0016032 viral reproduction 1.050183e-10
GO:0043624 cellular protein complex disassembly 1.750861e-10
GO:0030262 apoptotic nuclear change 5.568574e-10
GO:0043241 protein complex disassembly 9.325197e-10
GO:0000236 mitotic prometaphase 2.296125e-9
GO:0000088 mitotic prophase 4.259476e-9
GO:0006412 translation 8.154606e-9
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 1.211092e-8
GO:0016071 mRNA metabolic process 1.253234e-8
GO:0010498 proteasomal protein catabolic process 1.385914e-8
GO:0048280 vesicle fusion with Golgi apparatus 1.532698e-8
GO:0097039 protein linear polyubiquitination 2.017070e-8
GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway 2.394444e-8
GO:0007094 mitotic cell cycle spindle assembly checkpoint 3.760990e-8
GO:0010564 regulation of cell cycle process 4.228090e-8
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 5.074410e-8
GO:0007093 mitotic cell cycle checkpoint 5.085028e-8
GO:0022403 cell cycle phase 5.177915e-8
GO:0071173 spindle assembly checkpoint 5.205839e-8
GO:0071174 mitotic cell cycle spindle checkpoint 5.551587e-8
GO:0000278 mitotic cell cycle 6.550270e-8
GO:0021846 cell proliferation in forebrain 7.330348e-8
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 8.650745e-8
GO:0031577 spindle checkpoint 9.208132e-8
GO:0045906 negative regulation of vasoconstriction 1.367649e-7
GO:0000279 M phase 1.529193e-7
GO:0022027 interkinetic nuclear migration 1.549884e-7
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 1.702430e-7
GO:0048285 organelle fission 1.908396e-7
GO:2000659 regulation of interleukin-1-mediated signaling pathway 2.388695e-7
GO:0090304 nucleic acid metabolic process 2.483572e-7
GO:0000209 protein polyubiquitination 2.620196e-7
GO:0090281 negative regulation of calcium ion import 3.257041e-7
GO:0071584 negative regulation of zinc ion import 3.257041e-7
GO:0034660 ncRNA metabolic process 3.299663e-7
GO:0007067 mitosis 3.914136e-7
GO:0032581 ER-dependent peroxisome organization 4.240947e-7
GO:0006139 nucleobase-containing compound metabolic process 4.698343e-7
GO:0010506 regulation of autophagy 4.995173e-7
GO:0031167 rRNA methylation 5.318902e-7
GO:0045005 maintenance of fidelity involved in DNA-dependent DNA replication 6.955858e-7
GO:0035928 rRNA import into mitochondrion 6.959549e-7
GO:0042254 ribosome biogenesis 9.126449e-7
GO:0051351 positive regulation of ligase activity 1.039641e-6
GO:0000087 M phase of mitotic cell cycle 1.090721e-6
GO:0034766 negative regulation of ion transmembrane transport 1.133276e-6
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.190870e-6
GO:0045839 negative regulation of mitosis 1.221896e-6
GO:0010587 miRNA catabolic process 1.403697e-6
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 1.624583e-6
GO:0051647 nucleus localization 1.698575e-6
GO:0010310 regulation of hydrogen peroxide metabolic process 1.965080e-6
GO:0090305 nucleic acid phosphodiester bond hydrolysis 1.978067e-6
GO:0051029 rRNA transport 1.988893e-6
GO:0046796 viral genome transport in host cell 2.009909e-6
GO:0006611 protein export from nucleus 2.138495e-6
GO:0006396 RNA processing 2.538772e-6
GO:0000154 rRNA modification 2.544613e-6
GO:0031018 endocrine pancreas development 2.546581e-6
GO:0080009 mRNA methylation 2.613476e-6
GO:0042255 ribosome assembly 3.251503e-6
GO:0001510 RNA methylation 3.290727e-6
GO:0042396 phosphagen biosynthetic process 3.971843e-6
GO:0051340 regulation of ligase activity 4.582390e-6
GO:0071585 detoxification of cadmium ion 5.010060e-6
GO:0051443 positive regulation of ubiquitin-protein ligase activity 5.373093e-6
GO:0048387 negative regulation of retinoic acid receptor signaling pathway 5.525514e-6
GO:0071158 positive regulation of cell cycle arrest 6.030938e-6
GO:0010467 gene expression 6.270685e-6
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 6.525095e-6
GO:0033574 response to testosterone stimulus 7.637376e-6
GO:0030071 regulation of mitotic metaphase/anaphase transition 7.706036e-6
GO:0070979 protein K11-linked ubiquitination 7.964025e-6
GO:0046479 glycosphingolipid catabolic process 8.640619e-6
GO:0031297 replication fork processing 1.030098e-5
GO:0051301 cell division 1.096540e-5
GO:0046314 phosphocreatine biosynthetic process 1.105328e-5
GO:0031398 positive regulation of protein ubiquitination 1.111935e-5
GO:0034728 nucleosome organization 1.152567e-5
GO:0006529 asparagine biosynthetic process 1.262170e-5
GO:0031570 DNA integrity checkpoint 1.336589e-5
GO:0035229 positive regulation of glutamate-cysteine ligase activity 1.456798e-5
GO:0000077 DNA damage checkpoint 1.763597e-5
GO:0006552 leucine catabolic process 1.791181e-5
GO:0044265 cellular macromolecule catabolic process 1.873461e-5
GO:0051974 negative regulation of telomerase activity 2.012923e-5
GO:0034641 cellular nitrogen compound metabolic process 2.121764e-5
GO:0051438 regulation of ubiquitin-protein ligase activity 2.122094e-5
GO:0000712 resolution of meiotic recombination intermediates 2.168060e-5
GO:0051444 negative regulation of ubiquitin-protein ligase activity 2.196926e-5
GO:0071539 protein localization to centrosome 2.259085e-5
GO:0007346 regulation of mitotic cell cycle 2.786225e-5
GO:0022402 cell cycle process 3.120399e-5
GO:0034453 microtubule anchoring 3.185071e-5
GO:0046477 glycosylceramide catabolic process 3.220593e-5
GO:0071843 cellular component biogenesis at cellular level 3.302640e-5
GO:0006458 'de novo' protein folding 3.598477e-5
GO:0046950 cellular ketone body metabolic process 3.970687e-5
GO:0022613 ribonucleoprotein complex biogenesis 3.973772e-5
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 4.113440e-5
GO:0016073 snRNA metabolic process 4.308962e-5
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 4.329904e-5
GO:0050902 leukocyte adhesive activation 4.329904e-5
GO:0002502 peptide antigen assembly with MHC class I protein complex 4.357003e-5
GO:0051603 proteolysis involved in cellular protein catabolic process 4.406292e-5
GO:0006268 DNA unwinding involved in replication 4.414427e-5
GO:0006398 histone mRNA 3'-end processing 4.640288e-5
GO:0034470 ncRNA processing 4.973677e-5
GO:0031575 mitotic cell cycle G1/S transition checkpoint 5.134387e-5
GO:0032446 protein modification by small protein conjugation 5.195371e-5
GO:0032365 intracellular lipid transport 6.300011e-5
GO:0006511 ubiquitin-dependent protein catabolic process 6.608485e-5
GO:0031427 response to methotrexate 6.785454e-5
GO:0016567 protein ubiquitination 6.972145e-5
GO:0008334 histone mRNA metabolic process 7.159845e-5
GO:0043550 regulation of lipid kinase activity 7.203897e-5
GO:0006333 chromatin assembly or disassembly 7.537957e-5
GO:0046951 ketone body biosynthetic process 7.743651e-5
GO:0030953 astral microtubule organization 7.917097e-5
GO:0031396 regulation of protein ubiquitination 7.925107e-5
GO:0034621 cellular macromolecular complex subunit organization 7.988224e-5
GO:0019941 modification-dependent protein catabolic process 8.021843e-5
GO:0006353 transcription termination, DNA-dependent 8.159446e-5
GO:0034661 ncRNA catabolic process 8.558906e-5
GO:0071779 G1/S transition checkpoint 9.003607e-5
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 9.118580e-5
GO:0034080 CenH3-containing nucleosome assembly at centromere 9.399666e-5
GO:0071894 histone H2B conserved C-terminal lysine ubiquitination 9.403836e-5
GO:0021933 radial glia guided migration of cerebellar granule cell 1.000842e-4
GO:0043632 modification-dependent macromolecule catabolic process 1.030244e-4
GO:0051084 'de novo' posttranslational protein folding 1.031918e-4
GO:0007196 inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway 1.125469e-4
GO:0072422 signal transduction involved in DNA damage checkpoint 1.163578e-4
GO:0045665 negative regulation of neuron differentiation 1.177859e-4
GO:0000082 G1/S transition of mitotic cell cycle 1.224444e-4
GO:0008298 intracellular mRNA localization 1.249552e-4
GO:0070127 tRNA aminoacylation for mitochondrial protein translation 1.288796e-4
GO:0007100 mitotic centrosome separation 1.293594e-4
GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation 1.293594e-4
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.363583e-4
GO:0016070 RNA metabolic process 1.379327e-4
GO:0006807 nitrogen compound metabolic process 1.385474e-4
GO:0051208 sequestering of calcium ion 1.448068e-4
GO:0044257 cellular protein catabolic process 1.459986e-4
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 1.526022e-4
GO:0006545 glycine biosynthetic process 1.535644e-4
GO:0043405 regulation of MAP kinase activity 1.599034e-4
GO:0070059 apoptosis in response to endoplasmic reticulum stress 1.681844e-4
GO:0072404 signal transduction involved in G1/S transition checkpoint 1.760995e-4
GO:0043951 negative regulation of cAMP-mediated signaling 1.820563e-4
GO:0007210 serotonin receptor signaling pathway 1.880208e-4
GO:0006683 galactosylceramide catabolic process 1.905022e-4
GO:0042026 protein refolding 1.933007e-4
GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint 1.941989e-4
GO:0032851 positive regulation of Rab GTPase activity 1.998012e-4
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 2.051213e-4
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 2.051213e-4
GO:0043653 mitochondrial fragmentation involved in apoptosis 2.198469e-4
GO:0072395 signal transduction involved in cell cycle checkpoint 2.216322e-4
GO:0000089 mitotic metaphase 2.280926e-4
GO:0071569 protein ufmylation 2.293506e-4
GO:0051900 regulation of mitochondrial depolarization 2.338260e-4
GO:0000216 M/G1 transition of mitotic cell cycle 2.451522e-4
GO:0019377 glycolipid catabolic process 2.478872e-4
GO:0015074 DNA integration 2.512836e-4
GO:0031397 negative regulation of protein ubiquitination 2.579351e-4
GO:0042770 signal transduction in response to DNA damage 2.613063e-4
GO:0043406 positive regulation of MAP kinase activity 2.651334e-4
GO:2000660 negative regulation of interleukin-1-mediated signaling pathway 2.687280e-4
GO:0046105 thymidine biosynthetic process 2.811801e-4
GO:0032232 negative regulation of actin filament bundle assembly 3.201466e-4
GO:0006677 glycosylceramide metabolic process 3.224222e-4
GO:0090218 positive regulation of lipid kinase activity 3.233686e-4
GO:0006260 DNA replication 3.256996e-4
GO:0042256 mature ribosome assembly 3.265500e-4
GO:0051865 protein autoubiquitination 3.400627e-4
GO:0031497 chromatin assembly 3.461317e-4
GO:0006551 leucine metabolic process 3.470317e-4
GO:0016072 rRNA metabolic process 3.762530e-4
GO:0071824 protein-DNA complex subunit organization 3.823163e-4
GO:0046929 negative regulation of neurotransmitter secretion 3.852250e-4
GO:0032964 collagen biosynthetic process 3.925308e-4
GO:0006189 'de novo' IMP biosynthetic process 3.929704e-4
GO:0034619 cellular chaperone-mediated protein complex assembly 4.056848e-4
GO:0007088 regulation of mitosis 4.208485e-4
GO:0008608 attachment of spindle microtubules to kinetochore 4.286505e-4
GO:0031055 chromatin remodeling at centromere 4.410187e-4
GO:0061351 neural precursor cell proliferation 4.592332e-4
GO:0001839 neural plate morphogenesis 4.734503e-4
GO:0010592 positive regulation of lamellipodium assembly 4.791807e-4
GO:0090068 positive regulation of cell cycle process 4.824007e-4
GO:0007049 cell cycle 5.174418e-4
GO:0006334 nucleosome assembly 5.273432e-4
GO:2000045 regulation of G1/S transition of mitotic cell cycle 5.291454e-4
GO:0000093 mitotic telophase 5.295338e-4
GO:0022617 extracellular matrix disassembly 5.405307e-4
GO:0015693 magnesium ion transport 5.405307e-4
GO:0022004 midbrain-hindbrain boundary maturation during brain development 5.420763e-4
GO:2000002 negative regulation of DNA damage checkpoint 5.420763e-4
GO:0021588 cerebellum formation 5.420763e-4
GO:0021551 central nervous system morphogenesis 5.420763e-4
GO:0009070 serine family amino acid biosynthetic process 5.455147e-4
GO:0006882 cellular zinc ion homeostasis 6.114135e-4
GO:0010800 positive regulation of peptidyl-threonine phosphorylation 6.400929e-4
GO:0051902 negative regulation of mitochondrial depolarization 6.615425e-4
GO:0045040 protein import into mitochondrial outer membrane 6.670486e-4
GO:0006086 acetyl-CoA biosynthetic process from pyruvate 6.738346e-4
GO:0007051 spindle organization 6.895308e-4
GO:0048103 somatic stem cell division 7.436786e-4
GO:0043271 negative regulation of ion transport 7.538367e-4
GO:0006853 carnitine shuttle 7.936351e-4
GO:0070543 response to linoleic acid 8.233449e-4
GO:0090007 regulation of mitotic anaphase 8.233449e-4
GO:0034696 response to prostaglandin F stimulus 8.233449e-4
GO:0031120 snRNA pseudouridine synthesis 8.233449e-4
GO:0006361 transcription initiation from RNA polymerase I promoter 8.644602e-4
GO:0043029 T cell homeostasis 8.789659e-4
GO:0046104 thymidine metabolic process 8.882684e-4
GO:0032912 negative regulation of transforming growth factor beta2 production 9.463575e-4
GO:0070925 organelle assembly 9.764671e-4
GO:0006661 phosphatidylinositol biosynthetic process 9.768779e-4
GO:0031122 cytoplasmic microtubule organization 9.777363e-4
GO:0051154 negative regulation of striated muscle cell differentiation 1.033480e-3
GO:0048385 regulation of retinoic acid receptor signaling pathway 1.071250e-3
GO:0042398 cellular modified amino acid biosynthetic process 1.073803e-3
GO:0042273 ribosomal large subunit biogenesis 1.078439e-3
GO:0030219 megakaryocyte differentiation 1.078439e-3
GO:0006974 response to DNA damage stimulus 1.084800e-3
GO:0042989 sequestering of actin monomers 1.091918e-3
GO:2000249 regulation of actin cytoskeleton reorganization 1.101725e-3
GO:0014041 regulation of neuron maturation 1.110223e-3
GO:0061101 neuroendocrine cell differentiation 1.111701e-3
GO:0035372 protein localization to microtubule 1.111701e-3
GO:0060263 regulation of respiratory burst 1.148932e-3
GO:0006261 DNA-dependent DNA replication 1.155035e-3
GO:0006600 creatine metabolic process 1.195694e-3
GO:0051583 dopamine uptake 1.298866e-3
GO:0000375 RNA splicing, via transesterification reactions 1.310621e-3
GO:0015761 mannose transport 1.364680e-3
GO:0006369 termination of RNA polymerase II transcription 1.372143e-3
GO:0006379 mRNA cleavage 1.373634e-3
GO:0006513 protein monoubiquitination 1.385501e-3
GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity 1.395355e-3
GO:0000398 nuclear mRNA splicing, via spliceosome 1.402750e-3
GO:0001843 neural tube closure 1.409598e-3
GO:0006110 regulation of glycolysis 1.419149e-3
GO:0019376 galactolipid catabolic process 1.432662e-3
GO:0032543 mitochondrial translation 1.438159e-3
GO:0071502 cellular response to temperature stimulus 1.509774e-3
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 1.541792e-3
GO:0007521 muscle cell fate determination 1.569744e-3
GO:0009057 macromolecule catabolic process 1.662123e-3
GO:0071279 cellular response to cobalt ion 1.666850e-3
GO:0010637 negative regulation of mitochondrial fusion 1.666850e-3
GO:0032074 negative regulation of nuclease activity 1.666850e-3
GO:0010834 telomere maintenance via telomere shortening 1.668964e-3
GO:0060606 tube closure 1.735013e-3
GO:0006188 IMP biosynthetic process 1.746419e-3
GO:0045204 MAPK export from nucleus 1.773787e-3
GO:0045209 MAPK phosphatase export from nucleus, leptomycin B sensitive 1.773787e-3
GO:0009794 regulation of mitotic cell cycle, embryonic 1.780673e-3
GO:0045792 negative regulation of cell size 1.793423e-3
GO:0048742 regulation of skeletal muscle fiber development 1.819459e-3
GO:0009069 serine family amino acid metabolic process 1.898508e-3
GO:0007127 meiosis I 1.922188e-3
GO:0085020 protein K6-linked ubiquitination 1.973363e-3
GO:0032066 nucleolus to nucleoplasm transport 1.981431e-3
GO:0060947 cardiac vascular smooth muscle cell differentiation 2.010862e-3
GO:0016180 snRNA processing 2.060556e-3
GO:0060136 embryonic process involved in female pregnancy 2.082312e-3
GO:0014020 primary neural tube formation 2.086799e-3
GO:0038007 netrin-activated signaling pathway 2.167340e-3
GO:0070842 aggresome assembly 2.190444e-3
GO:0031054 pre-miRNA processing 2.228045e-3
GO:0051661 maintenance of centrosome location 2.255904e-3
GO:2000781 positive regulation of double-strand break repair 2.313127e-3
GO:0019068 virion assembly 2.313127e-3
GO:0030163 protein catabolic process 2.321667e-3
GO:0043375 CD8-positive, alpha-beta T cell lineage commitment 2.330305e-3
GO:0032848 negative regulation of cellular pH reduction 2.330305e-3
GO:0014042 positive regulation of neuron maturation 2.330305e-3
GO:0021747 cochlear nucleus development 2.330305e-3
GO:0006363 termination of RNA polymerase I transcription 2.332465e-3
GO:0051926 negative regulation of calcium ion transport 2.402379e-3
GO:0051131 chaperone-mediated protein complex assembly 2.402941e-3
GO:0021915 neural tube development 2.403793e-3
GO:0046514 ceramide catabolic process 2.471442e-3
GO:0071900 regulation of protein serine/threonine kinase activity 2.609889e-3
GO:0048246 macrophage chemotaxis 2.636799e-3
GO:0009106 lipoate metabolic process 2.736566e-3
GO:0009726 detection of endogenous stimulus 2.843238e-3
GO:0035307 positive regulation of protein dephosphorylation 2.843626e-3
GO:0046732 active induction of host immune response by virus 2.867535e-3
GO:0001776 leukocyte homeostasis 2.903535e-3
GO:0034501 protein localization to kinetochore 2.919403e-3
GO:0070936 protein K48-linked ubiquitination 2.965868e-3
GO:0061144 alveolar secondary septum development 2.973986e-3
GO:0046668 regulation of retinal cell programmed cell death 3.012741e-3
GO:0051324 prophase 3.026511e-3
GO:0010823 negative regulation of mitochondrion organization 3.043111e-3
GO:0019229 regulation of vasoconstriction 3.081652e-3
GO:0034115 negative regulation of heterotypic cell-cell adhesion 3.105170e-3
GO:0032730 positive regulation of interleukin-1 alpha production 3.186227e-3
GO:0060019 radial glial cell differentiation 3.194372e-3
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 3.240306e-3
GO:0060659 nipple sheath formation 3.389934e-3
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 3.389934e-3
GO:0060649 mammary gland bud elongation 3.389934e-3
GO:0009786 regulation of asymmetric cell division 3.498548e-3
GO:0008057 eye pigment granule organization 3.498548e-3
GO:0035306 positive regulation of dephosphorylation 3.516230e-3
GO:0046125 pyrimidine deoxyribonucleoside metabolic process 3.576717e-3
GO:0090272 negative regulation of fibroblast growth factor production 3.584937e-3
GO:0006808 regulation of nitrogen utilization 3.618366e-3
GO:0019388 galactose catabolic process 3.618366e-3
GO:0002260 lymphocyte homeostasis 3.653641e-3
GO:0010523 negative regulation of calcium ion transport into cytosol 3.677592e-3
GO:0010591 regulation of lamellipodium assembly 3.696934e-3
GO:0070534 protein K63-linked ubiquitination 3.831621e-3
GO:0006337 nucleosome disassembly 3.864035e-3
GO:2000725 regulation of cardiac muscle cell differentiation 3.914285e-3
GO:0051168 nuclear export 3.933425e-3
GO:0006681 galactosylceramide metabolic process 3.995111e-3
GO:0046730 induction of host immune response by virus 4.007458e-3
GO:0006085 acetyl-CoA biosynthetic process 4.013078e-3
GO:0009059 macromolecule biosynthetic process 4.050445e-3
GO:0001840 neural plate development 4.149591e-3
GO:0006325 chromatin organization 4.161501e-3
GO:0006259 DNA metabolic process 4.218995e-3
GO:0043496 regulation of protein homodimerization activity 4.239568e-3
GO:0071812 positive regulation of fever generation by positive regulation of prostaglandin secretion 4.303996e-3
GO:0071848 positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling 4.303996e-3
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 4.311676e-3
GO:0002052 positive regulation of neuroblast proliferation 4.315862e-3
GO:0072393 microtubule anchoring at microtubule organizing center 4.333889e-3
GO:0034112 positive regulation of homotypic cell-cell adhesion 4.440153e-3
GO:2000348 regulation of CD40 signaling pathway 4.459670e-3
GO:0055069 zinc ion homeostasis 4.459670e-3
GO:0051153 regulation of striated muscle cell differentiation 4.602112e-3
GO:0006360 transcription from RNA polymerase I promoter 4.654058e-3
GO:0046671 negative regulation of retinal cell programmed cell death 4.691021e-3
GO:0072385 minus-end-directed organelle transport along microtubule 4.694887e-3
GO:0042249 establishment of planar polarity of embryonic epithelium 4.825378e-3
GO:0006780 uroporphyrinogen III biosynthetic process 4.847229e-3
GO:0035519 protein K29-linked ubiquitination 4.866604e-3
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.866604e-3
GO:0001841 neural tube formation 4.873617e-3
GO:0051313 attachment of spindle microtubules to chromosome 4.883195e-3
GO:0003300 cardiac muscle hypertrophy 4.913959e-3
GO:0060045 positive regulation of cardiac muscle cell proliferation 5.034605e-3
GO:0030579 ubiquitin-dependent SMAD protein catabolic process 5.079082e-3
GO:0048002 antigen processing and presentation of peptide antigen 5.147669e-3
GO:0045769 negative regulation of asymmetric cell division 5.209147e-3
GO:0071277 cellular response to calcium ion 5.278631e-3
GO:0033326 cerebrospinal fluid secretion 5.392869e-3
GO:0007497 posterior midgut development 5.392869e-3
GO:0034436 glycoprotein transport 5.549314e-3
GO:0009720 detection of hormone stimulus 5.549314e-3
GO:0032741 positive regulation of interleukin-18 production 5.572074e-3
GO:0070371 ERK1 and ERK2 cascade 5.584113e-3
GO:0030330 DNA damage response, signal transduction by p53 class mediator 5.613068e-3
GO:0044314 protein K27-linked ubiquitination 5.827855e-3
GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway 5.827855e-3
GO:0001988 positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure 5.827855e-3
GO:0071635 negative regulation of transforming growth factor beta production 5.921046e-3
GO:0008612 peptidyl-lysine modification to hypusine 5.932556e-3
GO:0017145 stem cell division 5.950290e-3
GO:0001808 negative regulation of type IV hypersensitivity 6.026000e-3
GO:2000786 positive regulation of autophagic vacuole assembly 6.026000e-3
GO:0043486 histone exchange 6.027282e-3
GO:0006564 L-serine biosynthetic process 6.057901e-3
GO:0003254 regulation of membrane depolarization 6.286836e-3
GO:0000084 S phase of mitotic cell cycle 6.303145e-3
GO:0046605 regulation of centrosome cycle 6.393100e-3
GO:0021932 hindbrain radial glia guided cell migration 6.459782e-3
GO:0010508 positive regulation of autophagy 6.459782e-3
GO:0046521 sphingoid catabolic process 6.522673e-3
GO:0021873 forebrain neuroblast division 6.554454e-3
GO:0006298 mismatch repair 6.717425e-3
GO:0071374 cellular response to parathyroid hormone stimulus 6.781059e-3
GO:0006281 DNA repair 6.809423e-3
GO:0007216 metabotropic glutamate receptor signaling pathway 6.867874e-3
GO:0034349 glial cell apoptosis 6.867874e-3
GO:0044260 cellular macromolecule metabolic process 6.884497e-3
GO:0060025 regulation of synaptic activity 6.910149e-3
GO:0006338 chromatin remodeling 6.987967e-3
GO:0051466 positive regulation of corticotropin-releasing hormone secretion 7.120470e-3
GO:0045618 positive regulation of keratinocyte differentiation 7.120798e-3
GO:2000727 positive regulation of cardiac muscle cell differentiation 7.126714e-3
GO:2000987 positive regulation of behavioral fear response 7.126714e-3
GO:0003185 sinoatrial valve morphogenesis 7.126714e-3
GO:0035984 cellular response to trichostatin A 7.126714e-3
GO:0003138 primary heart field specification 7.126714e-3
GO:0021903 rostrocaudal neural tube patterning 7.142464e-3
GO:0016574 histone ubiquitination 7.158492e-3
GO:0046604 positive regulation of mitotic centrosome separation 7.209320e-3
GO:0007161 calcium-independent cell-matrix adhesion 7.209320e-3
GO:0007057 spindle assembly involved in female meiosis I 7.209320e-3
GO:0000188 inactivation of MAPK activity 7.273527e-3
GO:0060430 lung saccule development 7.342069e-3
GO:0051320 S phase 7.364830e-3
GO:0034635 glutathione transport 7.380857e-3
GO:0001807 regulation of type IV hypersensitivity 7.380857e-3
GO:0009107 lipoate biosynthetic process 7.380857e-3
GO:0051782 negative regulation of cell division 7.396359e-3
GO:0060282 positive regulation of oocyte development 7.712360e-3
GO:0010625 positive regulation of Schwann cell proliferation 7.712360e-3
GO:0045132 meiotic chromosome segregation 7.772550e-3
GO:0048247 lymphocyte chemotaxis 7.840571e-3
GO:0060061 Spemann organizer formation 7.881991e-3
GO:0048671 negative regulation of collateral sprouting 7.884170e-3
GO:0006435 threonyl-tRNA aminoacylation 8.172675e-3
GO:0060534 trachea cartilage development 8.333951e-3
GO:0045606 positive regulation of epidermal cell differentiation 8.333951e-3
GO:0043506 regulation of JUN kinase activity 8.339496e-3
GO:0065004 protein-DNA complex assembly 8.396179e-3
GO:0045986 negative regulation of smooth muscle contraction 8.480091e-3
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 8.480091e-3
GO:0009817 defense response to fungus, incompatible interaction 8.480091e-3
GO:0051972 regulation of telomerase activity 8.543132e-3
GO:0043044 ATP-dependent chromatin remodeling 8.639617e-3
GO:0001955 blood vessel maturation 8.691131e-3
GO:0045793 positive regulation of cell size 8.835325e-3
GO:0006007 glucose catabolic process 8.897417e-3
GO:0032214 negative regulation of telomere maintenance via semi-conservative replication 8.921880e-3
GO:0001309 age-dependent telomere shortening 8.921880e-3
GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 8.989975e-3
GO:0046952 ketone body catabolic process 8.989975e-3
GO:0010700 negative regulation of norepinephrine secretion 8.992837e-3
GO:0060489 planar dichotomous subdivision of terminal units involved in lung branching morphogenesis 9.076804e-3
GO:0060490 lateral sprouting involved in lung morphogenesis 9.076804e-3
GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis 9.076804e-3
GO:0002051 osteoblast fate commitment 9.076804e-3
GO:0009440 cyanate catabolic process 9.076804e-3
GO:0048105 establishment of body hair planar orientation 9.076804e-3
GO:0071902 positive regulation of protein serine/threonine kinase activity 9.148127e-3
GO:0016568 chromatin modification 9.149678e-3
GO:0002439 chronic inflammatory response to antigenic stimulus 9.302796e-3
GO:0034645 cellular macromolecule biosynthetic process 9.379312e-3
GO:0032367 intracellular cholesterol transport 9.534579e-3
GO:0070159 mitochondrial threonyl-tRNA aminoacylation 9.604060e-3
GO:0045661 regulation of myoblast differentiation 9.858547e-3
GO:0007285 primary spermatocyte growth 1.009253e-2
GO:0001731 formation of translation preinitiation complex 1.009253e-2
GO:0006403 RNA localization 1.009437e-2
GO:0010948 negative regulation of cell cycle process 1.022296e-2
GO:0000090 mitotic anaphase 1.022730e-2
GO:0051497 negative regulation of stress fiber assembly 1.027147e-2
GO:0051409 response to nitrosative stress 1.028516e-2
GO:0003333 amino acid transmembrane transport 1.034719e-2
GO:0051329 interphase of mitotic cell cycle 1.034835e-2
GO:0051169 nuclear transport 1.041660e-2
GO:0019374 galactolipid metabolic process 1.042094e-2
GO:0051640 organelle localization 1.054809e-2
GO:0034498 early endosome to Golgi transport 1.065837e-2
GO:0090075 relaxation of muscle 1.070794e-2
GO:0043949 regulation of cAMP-mediated signaling 1.070794e-2
GO:0045343 regulation of MHC class I biosynthetic process 1.078377e-2
GO:0031536 positive regulation of exit from mitosis 1.078659e-2
GO:0006839 mitochondrial transport 1.081284e-2
GO:0008652 cellular amino acid biosynthetic process 1.101820e-2
GO:0006364 rRNA processing 1.114539e-2
GO:0010799 regulation of peptidyl-threonine phosphorylation 1.121747e-2
GO:0048743 positive regulation of skeletal muscle fiber development 1.136345e-2
GO:0060364 frontal suture morphogenesis 1.164011e-2
GO:0001958 endochondral ossification 1.172486e-2
GO:0032740 positive regulation of interleukin-17 production 1.175427e-2
GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport 1.182909e-2
GO:0060112 generation of ovulation cycle rhythm 1.182909e-2
GO:0016241 regulation of macroautophagy 1.182909e-2
GO:0043471 regulation of cellular carbohydrate catabolic process 1.216368e-2
GO:0010826 negative regulation of centrosome duplication 1.240749e-2
GO:0035645 enteric smooth muscle cell differentiation 1.241507e-2
GO:0071228 cellular response to tumor cell 1.259882e-2
GO:0090251 protein localization involved in establishment of planar polarity 1.259882e-2
GO:0019402 galactitol metabolic process 1.259882e-2
GO:0044088 regulation of vacuole organization 1.259882e-2
GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus 1.259882e-2
GO:0006096 glycolysis 1.279552e-2
GO:0007522 visceral muscle development 1.283681e-2
GO:0003310 pancreatic A cell differentiation 1.288323e-2
GO:0060648 mammary gland bud morphogenesis 1.289399e-2
GO:0045907 positive regulation of vasoconstriction 1.301189e-2
GO:0006359 regulation of transcription from RNA polymerase III promoter 1.316761e-2
GO:0001782 B cell homeostasis 1.332276e-2
GO:0045663 positive regulation of myoblast differentiation 1.334225e-2
GO:0014065 phosphatidylinositol 3-kinase cascade 1.338208e-2
GO:0051325 interphase 1.338969e-2
GO:0090009 primitive streak formation 1.354388e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0016139 glycoside catabolic process 5.636723e-10
GO:0042069 regulation of catecholamine metabolic process 1.188270e-9
GO:0042053 regulation of dopamine metabolic process 2.063665e-9
GO:0060659 nipple sheath formation 3.328922e-9
GO:0060649 mammary gland bud elongation 3.328922e-9
GO:0033238 regulation of cellular amine metabolic process 8.165563e-9
GO:0009992 cellular water homeostasis 1.517956e-8
GO:0032872 regulation of stress-activated MAPK cascade 2.500505e-8
GO:0042424 catecholamine catabolic process 3.702186e-8
GO:0070831 basement membrane assembly 4.395899e-8
GO:0050668 positive regulation of homocysteine metabolic process 9.039334e-8
GO:0045963 negative regulation of dopamine metabolic process 9.039334e-8
GO:0071286 cellular response to magnesium ion 9.651755e-8
GO:0016137 glycoside metabolic process 1.910529e-7
GO:0016142 O-glycoside catabolic process 1.978288e-7
GO:0072355 histone H3-T3 phosphorylation 2.332687e-7
GO:0033240 positive regulation of cellular amine metabolic process 3.673654e-7
GO:0008334 histone mRNA metabolic process 3.791978e-7
GO:0000305 response to oxygen radical 3.853878e-7
GO:0042420 dopamine catabolic process 5.028711e-7
GO:0060658 nipple morphogenesis 5.975538e-7
GO:0015876 acetyl-CoA transport 6.725010e-7
GO:0061136 regulation of proteasomal protein catabolic process 6.782918e-7
GO:0060264 regulation of respiratory burst involved in inflammatory response 9.946081e-7
GO:0019285 glycine betaine biosynthetic process from choline 9.946081e-7
GO:0021568 rhombomere 2 development 9.946081e-7
GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development 1.197730e-6
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 1.540234e-6
GO:0007064 mitotic sister chromatid cohesion 1.873671e-6
GO:0030038 contractile actin filament bundle assembly 1.912954e-6
GO:0035912 dorsal aorta morphogenesis 1.912954e-6
GO:0051438 regulation of ubiquitin-protein ligase activity 2.853742e-6
GO:0071044 histone mRNA catabolic process 2.889785e-6
GO:0007059 chromosome segregation 3.397670e-6
GO:0016140 O-glycoside metabolic process 3.844799e-6
GO:0090398 cellular senescence 4.040307e-6
GO:0048680 positive regulation of axon regeneration 4.503209e-6
GO:0072079 nephron tubule formation 5.067329e-6
GO:0008652 cellular amino acid biosynthetic process 5.761632e-6
GO:0031331 positive regulation of cellular catabolic process 5.995410e-6
GO:0042428 serotonin metabolic process 6.286362e-6
GO:0090399 replicative senescence 6.617400e-6
GO:0045764 positive regulation of cellular amino acid metabolic process 6.900397e-6
GO:0060648 mammary gland bud morphogenesis 6.900397e-6
GO:0032873 negative regulation of stress-activated MAPK cascade 6.900397e-6
GO:0046477 glycosylceramide catabolic process 7.310216e-6
GO:0042417 dopamine metabolic process 8.020702e-6
GO:0033314 mitotic cell cycle DNA replication checkpoint 9.864016e-6
GO:0048285 organelle fission 1.020272e-5
GO:0007569 cell aging 1.400976e-5
GO:0030104 water homeostasis 1.570020e-5
GO:0060045 positive regulation of cardiac muscle cell proliferation 1.631256e-5
GO:0060263 regulation of respiratory burst 1.702242e-5
GO:0000413 protein peptidyl-prolyl isomerization 1.756890e-5
GO:0051340 regulation of ligase activity 1.756890e-5
GO:0060266 negative regulation of respiratory burst involved in inflammatory response 1.882697e-5
GO:0051451 myoblast migration 1.905009e-5
GO:0051176 positive regulation of sulfur metabolic process 1.905009e-5
GO:0048291 isotype switching to IgG isotypes 2.089362e-5
GO:0002368 B cell cytokine production 2.089362e-5
GO:0072513 positive regulation of secondary heart field cardioblast proliferation 2.315154e-5
GO:0006102 isocitrate metabolic process 2.315154e-5
GO:0090231 regulation of spindle checkpoint 2.451468e-5
GO:0031570 DNA integrity checkpoint 2.514272e-5
GO:0071248 cellular response to metal ion 2.632965e-5
GO:0021930 cerebellar granule cell precursor proliferation 2.712389e-5
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2.748918e-5
GO:0072086 specification of loop of Henle identity 2.748918e-5
GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 2.753297e-5
GO:0071711 basement membrane organization 2.854965e-5
GO:0000070 mitotic sister chromatid segregation 2.883786e-5
GO:0007067 mitosis 3.004348e-5
GO:0061333 renal tubule morphogenesis 3.215050e-5
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 3.377805e-5
GO:0043149 stress fiber assembly 3.490565e-5
GO:0060947 cardiac vascular smooth muscle cell differentiation 3.490565e-5
GO:0001947 heart looping 3.835436e-5
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 3.983810e-5
GO:0060347 heart trabecula formation 4.584388e-5
GO:0007379 segment specification 4.591130e-5
GO:0072199 regulation of mesenchymal cell proliferation involved in ureter development 4.671223e-5
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 4.857050e-5
GO:0000087 M phase of mitotic cell cycle 5.249764e-5
GO:0010735 positive regulation of transcription via serum response element binding 5.275826e-5
GO:0000077 DNA damage checkpoint 5.276762e-5
GO:0051443 positive regulation of ubiquitin-protein ligase activity 5.851532e-5
GO:0070830 tight junction assembly 6.371134e-5
GO:0018208 peptidyl-proline modification 6.888647e-5
GO:0072592 oxygen metabolic process 7.215522e-5
GO:0006578 betaine biosynthetic process 7.463743e-5
GO:0031663 lipopolysaccharide-mediated signaling pathway 7.464544e-5
GO:0006974 response to DNA damage stimulus 8.366501e-5
GO:0000819 sister chromatid segregation 8.511648e-5
GO:0019430 removal of superoxide radicals 8.983658e-5
GO:0033561 regulation of water loss via skin 9.544912e-5
GO:0032312 regulation of ARF GTPase activity 9.560330e-5
GO:0042772 DNA damage response, signal transduction resulting in transcription 1.036576e-4
GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 1.040433e-4
GO:0061351 neural precursor cell proliferation 1.124674e-4
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 1.170566e-4
GO:0006710 androgen catabolic process 1.195731e-4
GO:0090073 positive regulation of protein homodimerization activity 1.247186e-4
GO:0032874 positive regulation of stress-activated MAPK cascade 1.247186e-4
GO:0031572 G2/M transition DNA damage checkpoint 1.258322e-4
GO:2000781 positive regulation of double-strand break repair 1.358003e-4
GO:0060816 random inactivation of X chromosome 1.358003e-4
GO:0006666 3-keto-sphinganine metabolic process 1.358003e-4
GO:0006409 tRNA export from nucleus 1.358003e-4
GO:0072081 specification of nephron tubule identity 1.403771e-4
GO:0043950 positive regulation of cAMP-mediated signaling 1.461824e-4
GO:0019370 leukotriene biosynthetic process 1.540502e-4
GO:0031440 regulation of mRNA 3'-end processing 1.587109e-4
GO:0043508 negative regulation of JUN kinase activity 1.587109e-4
GO:0051145 smooth muscle cell differentiation 1.756466e-4
GO:0071287 cellular response to manganese ion 1.864877e-4
GO:0032057 negative regulation of translational initiation in response to stress 1.869810e-4
GO:0031442 positive regulation of mRNA 3'-end processing 1.869972e-4
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 1.920580e-4
GO:0042398 cellular modified amino acid biosynthetic process 1.984956e-4
GO:0009309 amine biosynthetic process 1.994354e-4
GO:0006189 'de novo' IMP biosynthetic process 2.007634e-4
GO:0001975 response to amphetamine 2.022188e-4
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 2.026150e-4
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2.084210e-4
GO:0001964 startle response 2.326787e-4
GO:0043496 regulation of protein homodimerization activity 2.445737e-4
GO:0019858 cytosine metabolic process 2.617365e-4
GO:0006449 regulation of translational termination 2.639386e-4
GO:0045652 regulation of megakaryocyte differentiation 2.641050e-4
GO:0048143 astrocyte activation 2.679232e-4
GO:0071474 cellular hyperosmotic response 2.702192e-4
GO:0002352 B cell negative selection 2.702192e-4
GO:0042135 neurotransmitter catabolic process 2.785786e-4
GO:0015732 prostaglandin transport 2.799072e-4
GO:0060012 synaptic transmission, glycinergic 2.799072e-4
GO:0035886 vascular smooth muscle cell differentiation 2.878710e-4
GO:0006691 leukotriene metabolic process 2.924812e-4
GO:0048854 brain morphogenesis 2.965815e-4
GO:0000303 response to superoxide 2.986894e-4
GO:0046394 carboxylic acid biosynthetic process 3.038094e-4
GO:0032012 regulation of ARF protein signal transduction 3.053992e-4
GO:0007093 mitotic cell cycle checkpoint 3.053992e-4
GO:0046329 negative regulation of JNK cascade 3.072868e-4
GO:0060081 membrane hyperpolarization 3.072868e-4
GO:0072107 positive regulation of ureteric bud formation 3.141159e-4
GO:0060359 response to ammonium ion 3.236436e-4
GO:0030050 vesicle transport along actin filament 3.236436e-4
GO:0071158 positive regulation of cell cycle arrest 3.293454e-4
GO:0019087 transformation of host cell by virus 3.307472e-4
GO:0006361 transcription initiation from RNA polymerase I promoter 3.307472e-4
GO:0044241 lipid digestion 3.365804e-4
GO:0043032 positive regulation of macrophage activation 3.558667e-4
GO:0000076 DNA replication checkpoint 3.572226e-4
GO:0007057 spindle assembly involved in female meiosis I 3.672384e-4
GO:0072078 nephron tubule morphogenesis 3.704615e-4
GO:0071156 regulation of cell cycle arrest 3.794885e-4
GO:0030220 platelet formation 3.858510e-4
GO:0060075 regulation of resting membrane potential 3.909348e-4
GO:0060409 positive regulation of acetylcholine metabolic process 4.040702e-4
GO:0002541 activation of plasma proteins involved in acute inflammatory response 4.040702e-4
GO:2000111 positive regulation of macrophage apoptosis 4.084082e-4
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 4.084082e-4
GO:0045081 negative regulation of interleukin-10 biosynthetic process 4.104499e-4
GO:0007256 activation of JNKK activity 4.283998e-4
GO:0006982 response to lipid hydroperoxide 4.556228e-4
GO:0000089 mitotic metaphase 4.646806e-4
GO:0055021 regulation of cardiac muscle tissue growth 4.771626e-4
GO:0090009 primitive streak formation 5.076053e-4
GO:0006289 nucleotide-excision repair 5.090318e-4
GO:0000279 M phase 5.145806e-4
GO:0006586 indolalkylamine metabolic process 5.441864e-4
GO:0051351 positive regulation of ligase activity 5.441864e-4
GO:0061180 mammary gland epithelium development 5.760795e-4
GO:0043297 apical junction assembly 5.836245e-4
GO:0061014 positive regulation of mRNA catabolic process 5.929412e-4
GO:0042176 regulation of protein catabolic process 6.055919e-4
GO:0072268 pattern specification involved in metanephros development 6.155729e-4
GO:0034619 cellular chaperone-mediated protein complex assembly 6.155729e-4
GO:0072080 nephron tubule development 6.317048e-4
GO:0006584 catecholamine metabolic process 6.570605e-4
GO:0061004 pattern specification involved in kidney development 6.583790e-4
GO:0061384 heart trabecular morphogenesis 6.635723e-4
GO:0044283 small molecule biosynthetic process 6.739440e-4
GO:0048645 organ formation 6.834707e-4
GO:0009896 positive regulation of catabolic process 6.875365e-4
GO:0072172 mesonephric tubule formation 6.982037e-4
GO:0071879 positive regulation of adrenergic receptor signaling pathway 7.293443e-4
GO:0050717 positive regulation of interleukin-1 alpha secretion 7.293443e-4
GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development 7.293443e-4
GO:0051602 response to electrical stimulus 7.476280e-4
GO:0048050 post-embryonic eye morphogenesis 7.612262e-4
GO:0009083 branched chain family amino acid catabolic process 7.699782e-4
GO:0048538 thymus development 7.993622e-4
GO:0072095 regulation of branch elongation involved in ureteric bud branching 8.083032e-4
GO:0014002 astrocyte development 8.528670e-4
GO:0042443 phenylethylamine metabolic process 8.867556e-4
GO:0051793 medium-chain fatty acid catabolic process 8.867556e-4
GO:0060025 regulation of synaptic activity 8.905641e-4
GO:2000987 positive regulation of behavioral fear response 8.905641e-4
GO:0035984 cellular response to trichostatin A 8.905641e-4
GO:0003185 sinoatrial valve morphogenesis 8.905641e-4
GO:0003138 primary heart field specification 8.905641e-4
GO:0007030 Golgi organization 9.095025e-4
GO:0045905 positive regulation of translational termination 9.421802e-4
GO:0006452 translational frameshifting 9.421802e-4
GO:0045901 positive regulation of translational elongation 9.421802e-4
GO:0021761 limbic system development 9.731978e-4
GO:0021782 glial cell development 9.859667e-4
GO:0070302 regulation of stress-activated protein kinase signaling cascade 1.009393e-3
GO:0016567 protein ubiquitination 1.011673e-3
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1.013904e-3
GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 1.014700e-3
GO:0031576 G2/M transition checkpoint 1.027017e-3
GO:0006463 steroid hormone receptor complex assembly 1.033621e-3
GO:0007096 regulation of exit from mitosis 1.053837e-3
GO:0000075 cell cycle checkpoint 1.101811e-3
GO:0006235 dTTP biosynthetic process 1.104691e-3
GO:0044088 regulation of vacuole organization 1.104691e-3
GO:0042744 hydrogen peroxide catabolic process 1.115256e-3
GO:0051276 chromosome organization 1.124609e-3
GO:0003207 cardiac chamber formation 1.151783e-3
GO:0051643 endoplasmic reticulum localization 1.164884e-3
GO:0048597 post-embryonic camera-type eye morphogenesis 1.164884e-3
GO:0071241 cellular response to inorganic substance 1.178504e-3
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 1.192182e-3
GO:0006734 NADH metabolic process 1.208322e-3
GO:0061326 renal tubule development 1.248920e-3
GO:0010922 positive regulation of phosphatase activity 1.280890e-3
GO:0006414 translational elongation 1.281665e-3
GO:0009147 pyrimidine nucleoside triphosphate metabolic process 1.307283e-3
GO:0048701 embryonic cranial skeleton morphogenesis 1.320292e-3
GO:0034498 early endosome to Golgi transport 1.342828e-3
GO:0055090 acylglycerol homeostasis 1.356456e-3
GO:0045019 negative regulation of nitric oxide biosynthetic process 1.378756e-3
GO:0033599 regulation of mammary gland epithelial cell proliferation 1.439076e-3
GO:0003179 heart valve morphogenesis 1.523143e-3
GO:0071374 cellular response to parathyroid hormone stimulus 1.523491e-3
GO:0006281 DNA repair 1.540093e-3
GO:0072422 signal transduction involved in DNA damage checkpoint 1.556616e-3
GO:0014898 cardiac muscle hypertrophy in response to stress 1.566904e-3
GO:0002309 T cell proliferation involved in immune response 1.582610e-3
GO:0034470 ncRNA processing 1.588964e-3
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway 1.597250e-3
GO:0003211 cardiac ventricle formation 1.637639e-3
GO:0046491 L-methylmalonyl-CoA metabolic process 1.713114e-3
GO:0001879 detection of yeast 1.713114e-3
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway 1.723516e-3
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 1.728816e-3
GO:0030431 sleep 1.784544e-3
GO:0048708 astrocyte differentiation 1.787056e-3
GO:0014050 negative regulation of glutamate secretion 1.809596e-3
GO:2000109 regulation of macrophage apoptosis 1.846906e-3
GO:0010042 response to manganese ion 1.866679e-3
GO:0016572 histone phosphorylation 1.918396e-3
GO:0034626 fatty acid elongation, polyunsaturated fatty acid 1.933467e-3
GO:0021546 rhombomere development 1.933467e-3
GO:0018027 peptidyl-lysine dimethylation 1.937706e-3
GO:0002227 innate immune response in mucosa 1.937706e-3
GO:0048679 regulation of axon regeneration 1.990737e-3
GO:0034644 cellular response to UV 2.005718e-3
GO:0010092 specification of organ identity 2.059114e-3
GO:0071459 protein localization to chromosome, centromeric region 2.078333e-3
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 2.078333e-3
GO:0060847 endothelial cell fate specification 2.083294e-3
GO:0046328 regulation of JNK cascade 2.133819e-3
GO:0046856 phosphatidylinositol dephosphorylation 2.141064e-3
GO:0006577 betaine metabolic process 2.154709e-3
GO:0034766 negative regulation of ion transmembrane transport 2.177671e-3
GO:0060572 morphogenesis of an epithelial bud 2.207760e-3
GO:0045626 negative regulation of T-helper 1 cell differentiation 2.224037e-3
GO:0001777 T cell homeostatic proliferation 2.224037e-3
GO:0016574 histone ubiquitination 2.227449e-3
GO:0003170 heart valve development 2.336696e-3
GO:0035855 megakaryocyte development 2.340162e-3
GO:0051131 chaperone-mediated protein complex assembly 2.355716e-3
GO:0009048 dosage compensation, by inactivation of X chromosome 2.355716e-3
GO:0007049 cell cycle 2.383045e-3
GO:0045862 positive regulation of proteolysis 2.429904e-3
GO:0045885 positive regulation of survival gene product expression 2.439049e-3
GO:0060068 vagina development 2.551284e-3
GO:0043030 regulation of macrophage activation 2.554434e-3
GO:0035050 embryonic heart tube development 2.575612e-3
GO:0060603 mammary gland duct morphogenesis 2.585185e-3
GO:0008635 activation of caspase activity by cytochrome c 2.619553e-3
GO:0006396 RNA processing 2.638083e-3
GO:0072193 ureter smooth muscle cell differentiation 2.647490e-3
GO:0010458 exit from mitosis 2.647490e-3
GO:0010467 gene expression 2.688728e-3
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 2.702314e-3
GO:0032912 negative regulation of transforming growth factor beta2 production 2.716913e-3
GO:0045665 negative regulation of neuron differentiation 2.762057e-3
GO:0002042 cell migration involved in sprouting angiogenesis 2.840482e-3
GO:0010826 negative regulation of centrosome duplication 2.896099e-3
GO:0035750 protein localization to myelin sheath abaxonal region 2.896099e-3
GO:0000115 regulation of transcription involved in S phase of mitotic cell cycle 2.896099e-3
GO:0042133 neurotransmitter metabolic process 2.922834e-3
GO:0051182 coenzyme transport 2.934129e-3
GO:0006188 IMP biosynthetic process 2.934129e-3
GO:0030330 DNA damage response, signal transduction by p53 class mediator 2.996606e-3
GO:0055026 negative regulation of cardiac muscle tissue development 3.001689e-3
GO:0046668 regulation of retinal cell programmed cell death 3.004324e-3
GO:0060292 long term synaptic depression 3.076280e-3
GO:0090068 positive regulation of cell cycle process 3.132433e-3
GO:0060420 regulation of heart growth 3.219695e-3
GO:0002076 osteoblast development 3.308670e-3
GO:0021986 habenula development 3.337657e-3
GO:0006680 glucosylceramide catabolic process 3.337657e-3
GO:0055024 regulation of cardiac muscle tissue development 3.350311e-3
GO:0006448 regulation of translational elongation 3.356015e-3
GO:0031396 regulation of protein ubiquitination 3.370264e-3
GO:0008033 tRNA processing 3.401935e-3
GO:0060948 cardiac vascular smooth muscle cell development 3.449364e-3
GO:0006265 DNA topological change 3.565175e-3
GO:0080135 regulation of cellular response to stress 3.601351e-3
GO:0072164 mesonephric tubule development 3.605840e-3
GO:0048703 embryonic viscerocranium morphogenesis 3.622588e-3
GO:0034442 regulation of lipoprotein oxidation 3.687810e-3
GO:0035058 nonmotile primary cilium assembly 3.743712e-3
GO:0045599 negative regulation of fat cell differentiation 3.754984e-3
GO:0035404 histone-serine phosphorylation 3.761271e-3
GO:0007043 cell-cell junction assembly 3.789074e-3
GO:0006576 cellular biogenic amine metabolic process 3.907054e-3
GO:0071877 regulation of adrenergic receptor signaling pathway 3.946277e-3
GO:0001824 blastocyst development 4.027576e-3
GO:0008612 peptidyl-lysine modification to hypusine 4.028909e-3
GO:0060043 regulation of cardiac muscle cell proliferation 4.032199e-3
GO:0001505 regulation of neurotransmitter levels 4.045974e-3
GO:0003283 atrial septum development 4.055391e-3
GO:0003349 epicardium-derived cardiac endothelial cell differentiation 4.059217e-3
GO:0046532 regulation of photoreceptor cell differentiation 4.062768e-3
GO:0032446 protein modification by small protein conjugation 4.112849e-3
GO:0072070 loop of Henle development 4.116490e-3
GO:2000822 regulation of behavioral fear response 4.146415e-3
GO:0072171 mesonephric tubule morphogenesis 4.146415e-3
GO:0006809 nitric oxide biosynthetic process 4.146415e-3
GO:0071294 cellular response to zinc ion 4.203301e-3
GO:0015780 nucleotide-sugar transport 4.203301e-3
GO:0071107 response to parathyroid hormone stimulus 4.403104e-3
GO:0019368 fatty acid elongation, unsaturated fatty acid 4.403104e-3
GO:0043968 histone H2A acetylation 4.403104e-3
GO:0060821 inactivation of X chromosome by DNA methylation 4.476717e-3
GO:0060064 Spemann organizer formation at the anterior end of the primitive streak 4.476717e-3
GO:0060267 positive regulation of respiratory burst 4.600999e-3
GO:0060058 positive regulation of apoptosis involved in mammary gland involution 4.684236e-3
GO:0032469 endoplasmic reticulum calcium ion homeostasis 4.684287e-3
GO:0022028 tangential migration from the subventricular zone to the olfactory bulb 4.684287e-3
GO:0009953 dorsal/ventral pattern formation 4.695480e-3
GO:0007521 muscle cell fate determination 4.765693e-3
GO:0000278 mitotic cell cycle 4.787178e-3
GO:0003139 secondary heart field specification 4.844679e-3
GO:0001886 endothelial cell morphogenesis 4.931022e-3
GO:0006868 glutamine transport 4.934745e-3
GO:0035633 maintenance of blood-brain barrier 5.073150e-3
GO:0090342 regulation of cell aging 5.094488e-3
GO:0070995 NADPH oxidation 5.196819e-3
GO:0072075 metanephric mesenchyme development 5.205579e-3
GO:0046015 regulation of transcription by glucose 5.206241e-3
GO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose 5.399438e-3
GO:0046839 phospholipid dephosphorylation 5.561619e-3
GO:0032026 response to magnesium ion 5.595595e-3
GO:0033239 negative regulation of cellular amine metabolic process 5.771507e-3
GO:0006270 DNA-dependent DNA replication initiation 5.771507e-3
GO:0034653 retinoic acid catabolic process 5.824503e-3
GO:0090161 Golgi ribbon formation 5.824503e-3
GO:0061050 regulation of cell growth involved in cardiac muscle cell development 5.824503e-3
GO:0043558 regulation of translational initiation in response to stress 5.824503e-3
GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process 5.824503e-3
GO:0032509 endosome transport via multivesicular body sorting pathway 5.824503e-3
GO:0033683 nucleotide-excision repair, DNA incision 5.824503e-3
GO:0031400 negative regulation of protein modification process 5.957034e-3
GO:0070407 oxidation-dependent protein catabolic process 6.059758e-3
GO:0043000 Golgi to plasma membrane CFTR protein transport 6.059758e-3
GO:0009794 regulation of mitotic cell cycle, embryonic 6.059758e-3
GO:0007062 sister chromatid cohesion 6.158088e-3
GO:0090197 positive regulation of chemokine secretion 6.199705e-3
GO:0051891 positive regulation of cardioblast differentiation 6.254484e-3
GO:0021766 hippocampus development 6.283007e-3
GO:2001013 epithelial cell proliferation involve in renal tubule morphogenesis 6.320895e-3
GO:0070509 calcium ion import 6.320895e-3
GO:0072160 nephron tubule epithelial cell differentiation 6.320895e-3
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 6.382249e-3
GO:0030264 nuclear fragmentation involved in apoptotic nuclear change 6.396799e-3
GO:0021526 medial motor column neuron differentiation 6.396799e-3
GO:0033523 histone H2B ubiquitination 6.486149e-3
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 6.488054e-3
GO:0090281 negative regulation of calcium ion import 6.488054e-3
GO:0070885 negative regulation of calcineurin-NFAT signaling pathway 6.488054e-3
GO:0071584 negative regulation of zinc ion import 6.488054e-3
GO:0034134 toll-like receptor 2 signaling pathway 6.488054e-3
GO:0051791 medium-chain fatty acid metabolic process 6.488054e-3
GO:0044314 protein K27-linked ubiquitination 6.488054e-3
GO:0048697 positive regulation of collateral sprouting in absence of injury 6.488054e-3
GO:0061056 sclerotome development 6.559696e-3
GO:0042402 cellular biogenic amine catabolic process 6.779541e-3
GO:0019276 UDP-N-acetylgalactosamine metabolic process 6.883507e-3
GO:0044240 multicellular organismal lipid catabolic process 6.947744e-3
GO:0019695 choline metabolic process 6.947744e-3
GO:0060523 prostate epithelial cord elongation 7.040700e-3
GO:0033137 negative regulation of peptidyl-serine phosphorylation 7.187910e-3
GO:0090403 oxidative stress-induced premature senescence 7.332968e-3
GO:0035907 dorsal aorta development 7.332968e-3
GO:0034770 histone H4-K20 methylation 7.332968e-3
GO:0048563 post-embryonic organ morphogenesis 7.342975e-3
GO:0070647 protein modification by small protein conjugation or removal 7.361366e-3
GO:0007008 outer mitochondrial membrane organization 7.404511e-3
GO:0003300 cardiac muscle hypertrophy 7.404511e-3
GO:0043506 regulation of JUN kinase activity 7.610361e-3
GO:0071542 dopaminergic neuron differentiation 7.711676e-3
GO:0035308 negative regulation of protein dephosphorylation 7.711676e-3
GO:0006730 one-carbon metabolic process 7.724122e-3
GO:0071108 protein K48-linked deubiquitination 7.749105e-3
GO:0000189 MAPK import into nucleus 7.930764e-3
GO:0046514 ceramide catabolic process 7.997392e-3
GO:0045936 negative regulation of phosphate metabolic process 8.041821e-3
GO:0060562 epithelial tube morphogenesis 8.160225e-3
GO:0060218 hemopoietic stem cell differentiation 8.171611e-3
GO:0031398 positive regulation of protein ubiquitination 8.247970e-3
GO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation 8.386903e-3
GO:0035910 ascending aorta morphogenesis 8.386903e-3
GO:0050748 negative regulation of lipoprotein metabolic process 8.386903e-3
GO:0000188 inactivation of MAPK activity 8.555026e-3
GO:0050891 multicellular organismal water homeostasis 8.589874e-3
GO:0007368 determination of left/right symmetry 8.689504e-3
GO:0007616 long-term memory 8.819543e-3
GO:0010921 regulation of phosphatase activity 8.878328e-3
GO:0061013 regulation of mRNA catabolic process 8.922978e-3
GO:0060061 Spemann organizer formation 8.956073e-3
GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway 8.956073e-3
GO:0070585 protein localization in mitochondrion 9.048414e-3
GO:0071236 cellular response to antibiotic 9.055836e-3
GO:0019048 virus-host interaction 9.071208e-3
GO:0030299 intestinal cholesterol absorption 9.106056e-3
GO:0010694 positive regulation of alkaline phosphatase activity 9.199183e-3
GO:0043500 muscle adaptation 9.287714e-3
GO:0001844 protein insertion into mitochondrial membrane involved in induction of apoptosis 9.391054e-3
GO:0051597 response to methylmercury 9.605593e-3
GO:0072074 kidney mesenchyme development 9.605593e-3
GO:0021510 spinal cord development 9.626308e-3
GO:0072655 establishment of protein localization in mitochondrion 9.634049e-3
GO:0071482 cellular response to light stimulus 9.634049e-3
GO:0042743 hydrogen peroxide metabolic process 9.888909e-3
GO:0010332 response to gamma radiation 1.013864e-2
GO:0045040 protein import into mitochondrial outer membrane 1.027469e-2
GO:0031987 locomotion involved in locomotory behavior 1.027469e-2
GO:0006325 chromatin organization 1.034368e-2
GO:0033554 cellular response to stress 1.037135e-2
GO:0055098 response to low-density lipoprotein particle stimulus 1.051729e-2
GO:0019377 glycolipid catabolic process 1.051729e-2
GO:0001825 blastocyst formation 1.059118e-2
GO:0071498 cellular response to fluid shear stress 1.074087e-2
GO:0035909 aorta morphogenesis 1.103710e-2
GO:0003309 type B pancreatic cell differentiation 1.122831e-2
GO:0046902 regulation of mitochondrial membrane permeability 1.124198e-2
GO:0071277 cellular response to calcium ion 1.134222e-2
GO:0034405 response to fluid shear stress 1.137957e-2
GO:0006801 superoxide metabolic process 1.137957e-2
GO:0009084 glutamine family amino acid biosynthetic process 1.152653e-2
GO:0090196 regulation of chemokine secretion 1.153431e-2
GO:0010944 negative regulation of transcription by competitive promoter binding 1.154429e-2
GO:2000725 regulation of cardiac muscle cell differentiation 1.167387e-2
GO:0071599 otic vesicle development 1.167387e-2
GO:0060399 positive regulation of growth hormone receptor signaling pathway 1.167856e-2
GO:0009443 pyridoxal 5'-phosphate salvage 1.175228e-2
GO:0032439 endosome localization 1.175228e-2
GO:0003026 regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback 1.175228e-2
GO:0035690 cellular response to drug 1.179058e-2
GO:0006479 protein methylation 1.181404e-2
GO:0071585 detoxification of cadmium ion 1.190034e-2
GO:0002355 detection of tumor cell 1.190034e-2
GO:0060763 mammary duct terminal end bud growth 1.211926e-2
GO:0060914 heart formation 1.213021e-2
GO:0009886 post-embryonic morphogenesis 1.216268e-2
GO:0021527 spinal cord association neuron differentiation 1.235483e-2
GO:0042363 fat-soluble vitamin catabolic process 1.246417e-2
GO:0032055 negative regulation of translation in response to stress 1.246417e-2
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 1.246417e-2
GO:0009799 specification of symmetry 1.246754e-2
GO:0016570 histone modification 1.248976e-2
GO:0009595 detection of biotic stimulus 1.249105e-2
GO:0032252 secretory granule localization 1.275984e-2
GO:0031124 mRNA 3'-end processing 1.294903e-2
GO:0032516 positive regulation of phosphoprotein phosphatase activity 1.317460e-2
GO:0090136 epithelial cell-cell adhesion 1.322714e-2
GO:0050853 B cell receptor signaling pathway 1.323320e-2
GO:0007006 mitochondrial membrane organization 1.330522e-2
GO:0060485 mesenchyme development 1.343728e-2
GO:0007493 endodermal cell fate determination 1.345302e-2
GO:0010614 negative regulation of cardiac muscle hypertrophy 1.345302e-2
GO:0006699 bile acid biosynthetic process 1.345302e-2
GO:0046496 nicotinamide nucleotide metabolic process 1.348110e-2
GO:0031058 positive regulation of histone modification 1.355703e-2
GO:0034372 very-low-density lipoprotein particle remodeling 1.358258e-2
GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint 1.382342e-2
GO:0060992 response to fungicide 1.384510e-2
GO:0045216 cell-cell junction organization 1.386270e-2
GO:0046826 negative regulation of protein export from nucleus 1.414483e-2
GO:0033299 secretion of lysosomal enzymes 1.422899e-2
GO:0006542 glutamine biosynthetic process 1.422899e-2
GO:0045824 negative regulation of innate immune response 1.472699e-2
GO:0001829 trophectodermal cell differentiation 1.502593e-2