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Novel motif:93

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name:motif93_TANTMTCTRWAT

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0050896 response to stimulus 9.249960e-27
GO:0007154 cell communication 3.495442e-20
GO:0023052 signaling 9.794193e-19
GO:0032501 multicellular organismal process 3.727483e-18
GO:0051716 cellular response to stimulus 5.354592e-17
GO:0007165 signal transduction 6.658787e-16
GO:0048513 organ development 9.100908e-16
GO:0002376 immune system process 2.850087e-15
GO:0048856 anatomical structure development 4.263344e-15
GO:0019674 NAD metabolic process 1.888026e-14
GO:0009888 tissue development 8.188344e-14
GO:0048731 system development 1.070813e-13
GO:0006950 response to stress 3.574449e-13
GO:0007275 multicellular organismal development 8.702316e-13
GO:0007166 cell surface receptor linked signaling pathway 1.903971e-12
GO:0032502 developmental process 2.174969e-12
GO:0009611 response to wounding 8.010971e-12
GO:0042221 response to chemical stimulus 1.114243e-11
GO:0019359 nicotinamide nucleotide biosynthetic process 3.303790e-11
GO:0031444 slow-twitch skeletal muscle fiber contraction 8.216976e-11
GO:0019363 pyridine nucleotide biosynthetic process 9.631913e-11
GO:0009653 anatomical structure morphogenesis 1.027820e-10
GO:0050789 regulation of biological process 1.754479e-10
GO:0009435 NAD biosynthetic process 2.856017e-10
GO:0043589 skin morphogenesis 3.124839e-10
GO:0002551 mast cell chemotaxis 3.708063e-10
GO:0030199 collagen fibril organization 5.332267e-10
GO:0046496 nicotinamide nucleotide metabolic process 5.468115e-10
GO:0003008 system process 8.084169e-10
GO:0051707 response to other organism 8.710539e-10
GO:0048660 regulation of smooth muscle cell proliferation 8.979171e-10
GO:0001542 ovulation from ovarian follicle 1.017656e-9
GO:0001915 negative regulation of T cell mediated cytotoxicity 1.486056e-9
GO:0015669 gas transport 1.645627e-9
GO:0051179 localization 1.930724e-9
GO:0065007 biological regulation 3.337122e-9
GO:0021858 GABAergic neuron differentiation in basal ganglia 4.219168e-9
GO:0050794 regulation of cellular process 4.985937e-9
GO:0031099 regeneration 6.147525e-9
GO:0019362 pyridine nucleotide metabolic process 6.302669e-9
GO:0042060 wound healing 6.690419e-9
GO:0002820 negative regulation of adaptive immune response 6.754792e-9
GO:0006887 exocytosis 8.610187e-9
GO:0040012 regulation of locomotion 1.349514e-8
GO:0002378 immunoglobulin biosynthetic process 1.763725e-8
GO:0006904 vesicle docking involved in exocytosis 1.970035e-8
GO:0051704 multi-organism process 1.975126e-8
GO:0018149 peptide cross-linking 2.052570e-8
GO:0006733 oxidoreduction coenzyme metabolic process 2.308910e-8
GO:0022406 membrane docking 2.489242e-8
GO:0006952 defense response 2.590574e-8
GO:0031640 killing of cells of other organism 3.379573e-8
GO:0070541 response to platinum ion 3.419151e-8
GO:0009607 response to biotic stimulus 3.510285e-8
GO:0050900 leukocyte migration 3.652949e-8
GO:0034392 negative regulation of smooth muscle cell apoptosis 4.816337e-8
GO:0015671 oxygen transport 6.913345e-8
GO:0051769 regulation of nitric-oxide synthase biosynthetic process 7.152865e-8
GO:0002710 negative regulation of T cell mediated immunity 8.278692e-8
GO:0032101 regulation of response to external stimulus 9.926348e-8
GO:0001911 negative regulation of leukocyte mediated cytotoxicity 1.204362e-7
GO:0048278 vesicle docking 1.594573e-7
GO:0051607 defense response to virus 1.737669e-7
GO:0019079 viral genome replication 1.938134e-7
GO:0031342 negative regulation of cell killing 2.530538e-7
GO:0007015 actin filament organization 2.877001e-7
GO:0006941 striated muscle contraction 3.116278e-7
GO:0051606 detection of stimulus 3.203422e-7
GO:0007186 G-protein coupled receptor protein signaling pathway 3.218555e-7
GO:0009168 purine ribonucleoside monophosphate biosynthetic process 3.314051e-7
GO:0009441 glycolate metabolic process 3.581346e-7
GO:0050906 detection of stimulus involved in sensory perception 3.678000e-7
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 3.974420e-7
GO:0009605 response to external stimulus 4.027468e-7
GO:0048683 regulation of collateral sprouting of intact axon in response to injury 4.302802e-7
GO:0006928 cellular component movement 4.591585e-7
GO:0030595 leukocyte chemotaxis 4.758112e-7
GO:0032940 secretion by cell 4.996467e-7
GO:0031100 organ regeneration 5.777736e-7
GO:0048869 cellular developmental process 6.569085e-7
GO:0072358 cardiovascular system development 6.776903e-7
GO:2000145 regulation of cell motility 7.669755e-7
GO:0030154 cell differentiation 8.784487e-7
GO:0070208 protein heterotrimerization 9.297725e-7
GO:0009887 organ morphogenesis 1.058400e-6
GO:0045444 fat cell differentiation 1.060857e-6
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 1.080087e-6
GO:0001101 response to acid 1.106733e-6
GO:0051270 regulation of cellular component movement 1.172572e-6
GO:0033211 adiponectin-mediated signaling pathway 1.218451e-6
GO:0033059 cellular pigmentation 1.247382e-6
GO:0014904 myotube cell development 1.251345e-6
GO:0007270 neuron-neuron synaptic transmission 1.288297e-6
GO:0043200 response to amino acid stimulus 1.371555e-6
GO:0002576 platelet degranulation 1.406656e-6
GO:0009167 purine ribonucleoside monophosphate metabolic process 1.427271e-6
GO:0051974 negative regulation of telomerase activity 1.479315e-6
GO:0002520 immune system development 1.512797e-6
GO:0001775 cell activation 1.594085e-6
GO:0040007 growth 1.688770e-6
GO:0070206 protein trimerization 1.693243e-6
GO:0001543 ovarian follicle rupture 1.698995e-6
GO:0001914 regulation of T cell mediated cytotoxicity 1.708133e-6
GO:0048713 regulation of oligodendrocyte differentiation 1.759368e-6
GO:0009617 response to bacterium 1.905433e-6
GO:0048662 negative regulation of smooth muscle cell proliferation 1.947741e-6
GO:0032252 secretory granule localization 1.948436e-6
GO:0030258 lipid modification 2.221761e-6
GO:0046903 secretion 2.312347e-6
GO:0016192 vesicle-mediated transport 2.313479e-6
GO:0030334 regulation of cell migration 2.329655e-6
GO:0001906 cell killing 2.689264e-6
GO:0048589 developmental growth 2.702155e-6
GO:0045137 development of primary sexual characteristics 2.742378e-6
GO:0048485 sympathetic nervous system development 3.157480e-6
GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly 3.821907e-6
GO:0048730 epidermis morphogenesis 4.155754e-6
GO:0034115 negative regulation of heterotypic cell-cell adhesion 4.362801e-6
GO:0045022 early endosome to late endosome transport 4.428590e-6
GO:0045685 regulation of glial cell differentiation 4.814603e-6
GO:0051648 vesicle localization 4.815556e-6
GO:0006651 diacylglycerol biosynthetic process 5.096574e-6
GO:0006769 nicotinamide metabolic process 5.215514e-6
GO:0050793 regulation of developmental process 5.738477e-6
GO:0006955 immune response 5.741676e-6
GO:0009156 ribonucleoside monophosphate biosynthetic process 5.881667e-6
GO:0006542 glutamine biosynthetic process 6.032920e-6
GO:0048729 tissue morphogenesis 6.386106e-6
GO:0043473 pigmentation 6.403862e-6
GO:0050777 negative regulation of immune response 6.530423e-6
GO:0006144 purine base metabolic process 6.591040e-6
GO:0018106 peptidyl-histidine phosphorylation 7.998347e-6
GO:0060761 negative regulation of response to cytokine stimulus 8.312973e-6
GO:0048468 cell development 8.342157e-6
GO:0051234 establishment of localization 8.458000e-6
GO:0010656 negative regulation of muscle cell apoptosis 8.605548e-6
GO:0015911 plasma membrane long-chain fatty acid transport 8.664154e-6
GO:0006810 transport 9.744758e-6
GO:0009820 alkaloid metabolic process 9.863218e-6
GO:0009593 detection of chemical stimulus 1.072587e-5
GO:0008406 gonad development 1.074210e-5
GO:0035414 negative regulation of catenin import into nucleus 1.130148e-5
GO:0019935 cyclic-nucleotide-mediated signaling 1.225905e-5
GO:0044030 regulation of DNA methylation 1.318871e-5
GO:0050907 detection of chemical stimulus involved in sensory perception 1.373901e-5
GO:0048583 regulation of response to stimulus 1.422611e-5
GO:0009161 ribonucleoside monophosphate metabolic process 1.462211e-5
GO:0034720 histone H3-K4 demethylation 1.488797e-5
GO:0060008 Sertoli cell differentiation 1.547275e-5
GO:0048534 hemopoietic or lymphoid organ development 1.614341e-5
GO:0006959 humoral immune response 1.615072e-5
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.639205e-5
GO:0003009 skeletal muscle contraction 1.721599e-5
GO:0002682 regulation of immune system process 1.953606e-5
GO:0060027 convergent extension involved in gastrulation 2.057639e-5
GO:0007181 transforming growth factor beta receptor complex assembly 2.249293e-5
GO:0010033 response to organic substance 2.533663e-5
GO:0030318 melanocyte differentiation 2.547556e-5
GO:0060137 maternal process involved in parturition 2.557975e-5
GO:0090370 negative regulation of cholesterol efflux 2.607913e-5
GO:0003012 muscle system process 2.681488e-5
GO:0030168 platelet activation 2.691572e-5
GO:0019585 glucuronate metabolic process 2.715737e-5
GO:0035630 bone mineralization involved in bone maturation 2.821939e-5
GO:0070098 chemokine-mediated signaling pathway 2.980491e-5
GO:0030097 hemopoiesis 2.994714e-5
GO:0006936 muscle contraction 3.114446e-5
GO:0014075 response to amine stimulus 3.177808e-5
GO:0043615 astrocyte cell migration 3.179701e-5
GO:0001960 negative regulation of cytokine-mediated signaling pathway 3.303101e-5
GO:0002377 immunoglobulin production 3.341732e-5
GO:0043201 response to leucine 3.343044e-5
GO:0046834 lipid phosphorylation 3.447869e-5
GO:0043603 cellular amide metabolic process 3.462292e-5
GO:0046854 phosphatidylinositol phosphorylation 3.501469e-5
GO:0010996 response to auditory stimulus 3.683444e-5
GO:0046504 glycerol ether biosynthetic process 3.683566e-5
GO:0050679 positive regulation of epithelial cell proliferation 3.710174e-5
GO:0071219 cellular response to molecule of bacterial origin 3.956514e-5
GO:0051272 positive regulation of cellular component movement 3.974685e-5
GO:0032400 melanosome localization 3.979055e-5
GO:0061039 ovum-producing ovary development 3.999161e-5
GO:0022603 regulation of anatomical structure morphogenesis 4.030546e-5
GO:0032728 positive regulation of interferon-beta production 4.091560e-5
GO:0048245 eosinophil chemotaxis 4.095613e-5
GO:0043163 cell envelope organization 4.135919e-5
GO:0007076 mitotic chromosome condensation 4.185950e-5
GO:0007155 cell adhesion 4.357461e-5
GO:0051877 pigment granule aggregation in cell center 4.422786e-5
GO:0032879 regulation of localization 4.656353e-5
GO:0046545 development of primary female sexual characteristics 4.657088e-5
GO:0014051 gamma-aminobutyric acid secretion 4.661515e-5
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 4.676129e-5
GO:0009100 glycoprotein metabolic process 5.052541e-5
GO:0035684 helper T cell extravasation 5.059313e-5
GO:0006029 proteoglycan metabolic process 5.136424e-5
GO:0002548 monocyte chemotaxis 5.233011e-5
GO:0010332 response to gamma radiation 5.323616e-5
GO:0071222 cellular response to lipopolysaccharide 5.409866e-5
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 5.587924e-5
GO:0034391 regulation of smooth muscle cell apoptosis 6.402773e-5
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound 6.402773e-5
GO:0050911 detection of chemical stimulus involved in sensory perception of smell 6.446426e-5
GO:0032387 negative regulation of intracellular transport 6.800604e-5
GO:0048247 lymphocyte chemotaxis 6.901922e-5
GO:0009987 cellular process 6.980400e-5
GO:0035412 regulation of catenin import into nucleus 6.982117e-5
GO:0009615 response to virus 7.004003e-5
GO:0060296 regulation of cilium beat frequency involved in ciliary motility 7.073461e-5
GO:0060429 epithelium development 7.393676e-5
GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 7.613096e-5
GO:0050776 regulation of immune response 7.735641e-5
GO:0051641 cellular localization 7.803769e-5
GO:0019932 second-messenger-mediated signaling 7.804051e-5
GO:0030335 positive regulation of cell migration 8.127777e-5
GO:0043129 surfactant homeostasis 8.498022e-5
GO:0007608 sensory perception of smell 8.612993e-5
GO:0001501 skeletal system development 8.700938e-5
GO:0048661 positive regulation of smooth muscle cell proliferation 8.718740e-5
GO:0071221 cellular response to bacterial lipopeptide 8.833859e-5
GO:0060644 mammary gland epithelial cell differentiation 8.838629e-5
GO:0045017 glycerolipid biosynthetic process 8.943129e-5
GO:0046398 UDP-glucuronate metabolic process 8.981743e-5
GO:0030166 proteoglycan biosynthetic process 9.034737e-5
GO:0030858 positive regulation of epithelial cell differentiation 9.296787e-5
GO:0050974 detection of mechanical stimulus involved in sensory perception 9.363560e-5
GO:0090317 negative regulation of intracellular protein transport 9.389740e-5
GO:0030261 chromosome condensation 9.466088e-5
GO:2000147 positive regulation of cell motility 9.486328e-5
GO:0050925 negative regulation of negative chemotaxis 9.615077e-5
GO:0032496 response to lipopolysaccharide 9.854754e-5
GO:0055065 metal ion homeostasis 1.004115e-4
GO:0051875 pigment granule localization 1.005853e-4
GO:0043353 enucleate erythrocyte differentiation 1.006946e-4
GO:0048769 sarcomerogenesis 1.053519e-4
GO:0016998 cell wall macromolecule catabolic process 1.135246e-4
GO:0051196 regulation of coenzyme metabolic process 1.156823e-4
GO:0070936 protein K48-linked ubiquitination 1.173771e-4
GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate 1.176950e-4
GO:0055074 calcium ion homeostasis 1.177603e-4
GO:0070887 cellular response to chemical stimulus 1.179705e-4
GO:0007219 Notch signaling pathway 1.209294e-4
GO:0030155 regulation of cell adhesion 1.227454e-4
GO:0035634 response to stilbenoid 1.239807e-4
GO:0048584 positive regulation of response to stimulus 1.265592e-4
GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 1.274542e-4
GO:0007267 cell-cell signaling 1.303640e-4
GO:0043931 ossification involved in bone maturation 1.315836e-4
GO:0048646 anatomical structure formation involved in morphogenesis 1.317191e-4
GO:0032989 cellular component morphogenesis 1.334765e-4
GO:0002237 response to molecule of bacterial origin 1.348531e-4
GO:0008585 female gonad development 1.395583e-4
GO:0008544 epidermis development 1.403681e-4
GO:0032431 activation of phospholipase A2 activity 1.405007e-4
GO:0048715 negative regulation of oligodendrocyte differentiation 1.405268e-4
GO:0060402 calcium ion transport into cytosol 1.405653e-4
GO:0009108 coenzyme biosynthetic process 1.422937e-4
GO:0010999 regulation of eIF2 alpha phosphorylation by heme 1.468951e-4
GO:0009589 detection of UV 1.468951e-4
GO:0021778 oligodendrocyte cell fate specification 1.475047e-4
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway 1.499217e-4
GO:0060759 regulation of response to cytokine stimulus 1.528311e-4
GO:0006874 cellular calcium ion homeostasis 1.540938e-4
GO:0007584 response to nutrient 1.548156e-4
GO:0010632 regulation of epithelial cell migration 1.585574e-4
GO:0016081 synaptic vesicle docking involved in exocytosis 1.598731e-4
GO:0045597 positive regulation of cell differentiation 1.675944e-4
GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 1.683305e-4
GO:0001963 synaptic transmission, dopaminergic 1.684217e-4
GO:0014047 glutamate secretion 1.702934e-4
GO:0003357 noradrenergic neuron differentiation 1.706509e-4
GO:0050953 sensory perception of light stimulus 1.709249e-4
GO:0006875 cellular metal ion homeostasis 1.719741e-4
GO:0040017 positive regulation of locomotion 1.720580e-4
GO:0032430 positive regulation of phospholipase A2 activity 1.766071e-4
GO:0048246 macrophage chemotaxis 1.799473e-4
GO:0007032 endosome organization 1.823165e-4
GO:0016477 cell migration 1.831585e-4
GO:0050801 ion homeostasis 1.834282e-4
GO:0030240 skeletal muscle thin filament assembly 1.851548e-4
GO:2000279 negative regulation of DNA biosynthetic process 1.914235e-4
GO:0042742 defense response to bacterium 1.961665e-4
GO:0001525 angiogenesis 1.968125e-4
GO:0030036 actin cytoskeleton organization 1.972162e-4
GO:0002440 production of molecular mediator of immune response 2.002935e-4
GO:0044036 cell wall macromolecule metabolic process 2.019342e-4
GO:0090023 positive regulation of neutrophil chemotaxis 2.025654e-4
GO:0051659 maintenance of mitochondrion location 2.072266e-4
GO:0019933 cAMP-mediated signaling 2.086428e-4
GO:2000334 positive regulation of blood microparticle formation 2.097122e-4
GO:0007548 sex differentiation 2.097883e-4
GO:0051883 killing of cells in other organism involved in symbiotic interaction 2.103294e-4
GO:0048791 calcium ion-dependent exocytosis of neurotransmitter 2.165523e-4
GO:0008104 protein localization 2.212569e-4
GO:0045091 regulation of retroviral genome replication 2.225379e-4
GO:0035444 nickel ion transmembrane transport 2.293061e-4
GO:0070627 ferrous iron import 2.293061e-4
GO:0015692 lead ion transport 2.293061e-4
GO:0015676 vanadium ion transport 2.293061e-4
GO:0006650 glycerophospholipid metabolic process 2.320029e-4
GO:0001944 vasculature development 2.340670e-4
GO:0070886 positive regulation of calcineurin-NFAT signaling pathway 2.351931e-4
GO:0015868 purine ribonucleotide transport 2.364577e-4
GO:0042178 xenobiotic catabolic process 2.390033e-4
GO:0008284 positive regulation of cell proliferation 2.410068e-4
GO:0042127 regulation of cell proliferation 2.446825e-4
GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages 2.454272e-4
GO:0050877 neurological system process 2.469333e-4
GO:0010259 multicellular organismal aging 2.472414e-4
GO:0010810 regulation of cell-substrate adhesion 2.532521e-4
GO:0030182 neuron differentiation 2.569562e-4
GO:0060081 membrane hyperpolarization 2.620812e-4
GO:0000904 cell morphogenesis involved in differentiation 2.624324e-4
GO:0071216 cellular response to biotic stimulus 2.627410e-4
GO:0072503 cellular divalent inorganic cation homeostasis 2.640438e-4
GO:0002320 lymphoid progenitor cell differentiation 2.690272e-4
GO:0070094 positive regulation of glucagon secretion 2.800958e-4
GO:0008038 neuron recognition 2.802036e-4
GO:0048732 gland development 2.837667e-4
GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 2.848408e-4
GO:0002684 positive regulation of immune system process 2.850174e-4
GO:0050931 pigment cell differentiation 2.858920e-4
GO:0006541 glutamine metabolic process 2.892695e-4
GO:0033034 positive regulation of myeloid cell apoptosis 2.960685e-4
GO:0042180 cellular ketone metabolic process 2.969561e-4
GO:0032648 regulation of interferon-beta production 3.001011e-4
GO:0001959 regulation of cytokine-mediated signaling pathway 3.001846e-4
GO:0000819 sister chromatid segregation 3.043963e-4
GO:0001932 regulation of protein phosphorylation 3.072138e-4
GO:2000178 negative regulation of neural precursor cell proliferation 3.145341e-4
GO:0043252 sodium-independent organic anion transport 3.151908e-4
GO:0046823 negative regulation of nucleocytoplasmic transport 3.157929e-4
GO:0048483 autonomic nervous system development 3.230706e-4
GO:0007601 visual perception 3.296575e-4
GO:0007018 microtubule-based movement 3.312625e-4
GO:0051640 organelle localization 3.327345e-4
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 3.425688e-4
GO:0046108 uridine metabolic process 3.441588e-4
GO:0001502 cartilage condensation 3.475438e-4
GO:0042402 cellular biogenic amine catabolic process 3.493273e-4
GO:0000070 mitotic sister chromatid segregation 3.497979e-4
GO:0019836 hemolysis by symbiont of host erythrocytes 3.520187e-4
GO:0034201 response to oleic acid 3.544426e-4
GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration 3.560187e-4
GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development 3.615635e-4
GO:0051646 mitochondrion localization 3.705626e-4
GO:0072507 divalent inorganic cation homeostasis 3.707537e-4
GO:0006954 inflammatory response 3.812759e-4
GO:0055080 cation homeostasis 3.846015e-4
GO:0045665 negative regulation of neuron differentiation 3.851698e-4
GO:0050881 musculoskeletal movement 3.864011e-4
GO:0032402 melanosome transport 3.892369e-4
GO:0015812 gamma-aminobutyric acid transport 3.912754e-4
GO:0006811 ion transport 3.921723e-4
GO:0051970 negative regulation of transmission of nerve impulse 4.137223e-4
GO:0019752 carboxylic acid metabolic process 4.171402e-4
GO:0032481 positive regulation of type I interferon production 4.232670e-4
GO:0030198 extracellular matrix organization 4.479744e-4
GO:0060632 regulation of microtubule-based movement 4.503345e-4
GO:0090022 regulation of neutrophil chemotaxis 4.612245e-4
GO:0048870 cell motility 4.668150e-4
GO:0051094 positive regulation of developmental process 4.681196e-4
GO:0030029 actin filament-based process 4.689923e-4
GO:0010720 positive regulation of cell development 4.722238e-4
GO:0010613 positive regulation of cardiac muscle hypertrophy 4.757840e-4
GO:0032274 gonadotropin secretion 4.765529e-4
GO:0048644 muscle organ morphogenesis 4.783675e-4
GO:0051188 cofactor biosynthetic process 4.936990e-4
GO:0000902 cell morphogenesis 5.155638e-4
GO:0045590 negative regulation of regulatory T cell differentiation 5.332757e-4
GO:0002707 negative regulation of lymphocyte mediated immunity 5.398968e-4
GO:0050878 regulation of body fluid levels 5.730968e-4
GO:0006732 coenzyme metabolic process 5.750432e-4
GO:0009101 glycoprotein biosynthetic process 5.865790e-4
GO:0043623 cellular protein complex assembly 5.874719e-4
GO:0051216 cartilage development 5.954479e-4
GO:0043046 DNA methylation involved in gamete generation 5.988752e-4
GO:0046826 negative regulation of protein export from nucleus 5.988752e-4
GO:0007399 nervous system development 6.021387e-4
GO:0035510 DNA dealkylation 6.060576e-4
GO:0046486 glycerolipid metabolic process 6.091204e-4
GO:0071840 cellular component organization or biogenesis 6.101923e-4
GO:0007530 sex determination 6.108031e-4
GO:0060401 cytosolic calcium ion transport 6.124975e-4
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 6.183111e-4
GO:0050902 leukocyte adhesive activation 6.183111e-4
GO:0048608 reproductive structure development 6.270153e-4
GO:0001910 regulation of leukocyte mediated cytotoxicity 6.299750e-4
GO:0045663 positive regulation of myoblast differentiation 6.376673e-4
GO:0006935 chemotaxis 6.439388e-4
GO:0002328 pro-B cell differentiation 6.508285e-4
GO:2000481 positive regulation of cAMP-dependent protein kinase activity 6.546501e-4
GO:2000534 positive regulation of renal albumin absorption 6.546501e-4
GO:2000461 negative regulation of eukaryotic cell surface binding 6.546501e-4
GO:2000478 positive regulation of metanephric glomerular visceral epithelial cell development 6.546501e-4
GO:0070994 detection of oxidative stress 6.546501e-4
GO:0071447 cellular response to hydroperoxide 6.662212e-4
GO:0048585 negative regulation of response to stimulus 6.737150e-4
GO:0021794 thalamus development 6.821779e-4
GO:0007596 blood coagulation 6.878971e-4
GO:0006175 dATP biosynthetic process 6.901112e-4
GO:0018202 peptidyl-histidine modification 6.974865e-4
GO:0019441 tryptophan catabolic process to kynurenine 6.984192e-4
GO:0042325 regulation of phosphorylation 7.039918e-4
GO:0003289 atrial septum primum morphogenesis 7.219413e-4
GO:0006082 organic acid metabolic process 7.234111e-4
GO:0040011 locomotion 7.256098e-4
GO:0031214 biomineral tissue development 7.364004e-4
GO:0048670 regulation of collateral sprouting 7.368420e-4
GO:0001568 blood vessel development 7.518184e-4
GO:0032854 positive regulation of Rap GTPase activity 7.594064e-4
GO:0032878 regulation of establishment or maintenance of cell polarity 7.765102e-4
GO:0045069 regulation of viral genome replication 7.780002e-4
GO:0046463 acylglycerol biosynthetic process 7.790517e-4
GO:0048549 positive regulation of pinocytosis 7.969166e-4
GO:0051239 regulation of multicellular organismal process 8.172658e-4
GO:0014912 negative regulation of smooth muscle cell migration 8.262802e-4
GO:0043420 anthranilate metabolic process 8.365103e-4
GO:0034516 response to vitamin B6 8.365103e-4
GO:0009581 detection of external stimulus 8.401080e-4
GO:0070373 negative regulation of ERK1 and ERK2 cascade 8.458674e-4
GO:0033157 regulation of intracellular protein transport 8.490241e-4
GO:0008037 cell recognition 8.521737e-4
GO:0070184 mitochondrial tyrosyl-tRNA aminoacylation 8.595391e-4
GO:0046660 female sex differentiation 8.606675e-4
GO:0042246 tissue regeneration 8.628980e-4
GO:0007599 hemostasis 8.711704e-4
GO:0009750 response to fructose stimulus 8.743350e-4
GO:0050805 negative regulation of synaptic transmission 8.998739e-4
GO:0031349 positive regulation of defense response 9.036130e-4
GO:0060326 cell chemotaxis 9.048915e-4
GO:0007179 transforming growth factor beta receptor signaling pathway 9.170559e-4
GO:0065008 regulation of biological quality 9.400422e-4
GO:0007409 axonogenesis 9.479753e-4
GO:0051186 cofactor metabolic process 9.561421e-4
GO:0046884 follicle-stimulating hormone secretion 9.625130e-4
GO:0032275 luteinizing hormone secretion 9.625130e-4
GO:0051904 pigment granule transport 9.838912e-4
GO:0030879 mammary gland development 9.861211e-4
GO:0010811 positive regulation of cell-substrate adhesion 9.936132e-4
GO:0055082 cellular chemical homeostasis 9.955856e-4
GO:0006873 cellular ion homeostasis 1.031172e-3
GO:0071229 cellular response to acid 1.041143e-3
GO:0032509 endosome transport via multivesicular body sorting pathway 1.044704e-3
GO:0060100 positive regulation of phagocytosis, engulfment 1.046005e-3
GO:0001666 response to hypoxia 1.052025e-3
GO:0051972 regulation of telomerase activity 1.057734e-3
GO:0060716 labyrinthine layer blood vessel development 1.061921e-3
GO:0051017 actin filament bundle assembly 1.062316e-3
GO:0051893 regulation of focal adhesion assembly 1.074294e-3
GO:0002690 positive regulation of leukocyte chemotaxis 1.096052e-3
GO:0000910 cytokinesis 1.096052e-3
GO:0090082 positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway 1.099072e-3
GO:0048519 negative regulation of biological process 1.105584e-3
GO:0032787 monocarboxylic acid metabolic process 1.116910e-3
GO:0007606 sensory perception of chemical stimulus 1.120022e-3
GO:0051155 positive regulation of striated muscle cell differentiation 1.145191e-3
GO:0007412 axon target recognition 1.145768e-3
GO:0032429 regulation of phospholipase A2 activity 1.150702e-3
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 1.154014e-3
GO:0019915 lipid storage 1.157230e-3
GO:0032990 cell part morphogenesis 1.165353e-3
GO:0006214 thymidine catabolic process 1.177659e-3
GO:0050654 chondroitin sulfate proteoglycan metabolic process 1.178329e-3
GO:0048666 neuron development 1.191866e-3
GO:0021761 limbic system development 1.194821e-3
GO:0043949 regulation of cAMP-mediated signaling 1.199055e-3
GO:0021779 oligodendrocyte cell fate commitment 1.199375e-3
GO:0032886 regulation of microtubule-based process 1.206890e-3
GO:0010243 response to organic nitrogen 1.222805e-3
GO:0060986 endocrine hormone secretion 1.234995e-3
GO:0043409 negative regulation of MAPKKK cascade 1.287705e-3
GO:0016198 axon choice point recognition 1.294328e-3
GO:0019442 tryptophan catabolic process to acetyl-CoA 1.296954e-3
GO:0051025 negative regulation of immunoglobulin secretion 1.299730e-3
GO:0021941 negative regulation of cerebellar granule cell precursor proliferation 1.299730e-3
GO:0033182 regulation of histone ubiquitination 1.299730e-3
GO:0045214 sarcomere organization 1.322574e-3
GO:0016043 cellular component organization 1.340636e-3
GO:0050920 regulation of chemotaxis 1.340768e-3
GO:0048812 neuron projection morphogenesis 1.343082e-3
GO:0090310 negative regulation of methylation-dependent chromatin silencing 1.366620e-3
GO:0001952 regulation of cell-matrix adhesion 1.367109e-3
GO:0051149 positive regulation of muscle cell differentiation 1.373324e-3
GO:0023057 negative regulation of signaling 1.377554e-3
GO:0060166 olfactory pit development 1.390532e-3
GO:0007204 elevation of cytosolic calcium ion concentration 1.418830e-3
GO:2000121 regulation of removal of superoxide radicals 1.422570e-3
GO:0010648 negative regulation of cell communication 1.425802e-3
GO:0021854 hypothalamus development 1.429157e-3
GO:0048878 chemical homeostasis 1.429234e-3
GO:0030104 water homeostasis 1.434706e-3
GO:0050982 detection of mechanical stimulus 1.443309e-3
GO:0070371 ERK1 and ERK2 cascade 1.450922e-3
GO:0007517 muscle organ development 1.455164e-3
GO:0048518 positive regulation of biological process 1.461791e-3
GO:0030252 growth hormone secretion 1.463924e-3
GO:0030728 ovulation 1.489702e-3
GO:0050923 regulation of negative chemotaxis 1.499029e-3
GO:0061013 regulation of mRNA catabolic process 1.502955e-3


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0007166 cell surface receptor linked signaling pathway 4.569610e-14
GO:0014904 myotube cell development 9.111034e-14
GO:0050654 chondroitin sulfate proteoglycan metabolic process 7.692125e-13
GO:0045821 positive regulation of glycolysis 3.085198e-12
GO:0060741 prostate gland stromal morphogenesis 6.739386e-12
GO:0035630 bone mineralization involved in bone maturation 1.058489e-11
GO:0006029 proteoglycan metabolic process 9.349565e-11
GO:0006110 regulation of glycolysis 1.117377e-10
GO:0043931 ossification involved in bone maturation 1.711133e-10
GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration 2.465556e-10
GO:0070977 bone maturation 6.617144e-10
GO:0034392 negative regulation of smooth muscle cell apoptosis 1.435245e-9
GO:0060766 negative regulation of androgen receptor signaling pathway 3.414125e-9
GO:2000179 positive regulation of neural precursor cell proliferation 4.729996e-9
GO:0050896 response to stimulus 7.722131e-9
GO:0048009 insulin-like growth factor receptor signaling pathway 1.175366e-8
GO:0042129 regulation of T cell proliferation 1.297142e-8
GO:0014896 muscle hypertrophy 1.346446e-8
GO:0050863 regulation of T cell activation 1.722624e-8
GO:0032878 regulation of establishment or maintenance of cell polarity 1.820097e-8
GO:0043519 regulation of myosin II filament organization 1.867208e-8
GO:0048608 reproductive structure development 2.188626e-8
GO:0034391 regulation of smooth muscle cell apoptosis 2.471242e-8
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 3.283123e-8
GO:0090201 negative regulation of release of cytochrome c from mitochondria 3.328277e-8
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 3.484123e-8
GO:0048015 phosphatidylinositol-mediated signaling 3.957750e-8
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein 4.153744e-8
GO:0045445 myoblast differentiation 4.482083e-8
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 4.608592e-8
GO:0009100 glycoprotein metabolic process 5.273009e-8
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 5.674909e-8
GO:0010823 negative regulation of mitochondrion organization 5.913454e-8
GO:0060271 cilium morphogenesis 8.119285e-8
GO:0002768 immune response-regulating cell surface receptor signaling pathway 9.533093e-8
GO:0043471 regulation of cellular carbohydrate catabolic process 1.164683e-7
GO:0097113 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering 1.325524e-7
GO:0014066 regulation of phosphatidylinositol 3-kinase cascade 2.005062e-7
GO:0060509 Type I pneumocyte differentiation 2.045631e-7
GO:0010592 positive regulation of lamellipodium assembly 2.460493e-7
GO:0003008 system process 2.574168e-7
GO:0051491 positive regulation of filopodium assembly 2.658949e-7
GO:0048856 anatomical structure development 2.797625e-7
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 3.058550e-7
GO:0002764 immune response-regulating signaling pathway 3.328032e-7
GO:0051489 regulation of filopodium assembly 3.428316e-7
GO:0032501 multicellular organismal process 4.243270e-7
GO:0030850 prostate gland development 4.257494e-7
GO:0040014 regulation of multicellular organism growth 4.459909e-7
GO:0035019 somatic stem cell maintenance 5.117776e-7
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 5.319682e-7
GO:0019827 stem cell maintenance 5.606490e-7
GO:0043409 negative regulation of MAPKKK cascade 8.498497e-7
GO:0051057 positive regulation of small GTPase mediated signal transduction 9.065036e-7
GO:0060736 prostate gland growth 9.555598e-7
GO:0030593 neutrophil chemotaxis 9.786592e-7
GO:0051450 myoblast proliferation 9.791583e-7
GO:0060463 lung lobe morphogenesis 1.026255e-6
GO:0060740 prostate gland epithelium morphogenesis 1.054566e-6
GO:0051239 regulation of multicellular organismal process 1.078855e-6
GO:0060512 prostate gland morphogenesis 1.259728e-6
GO:0060442 branching involved in prostate gland morphogenesis 1.358315e-6
GO:0060765 regulation of androgen receptor signaling pathway 1.384350e-6
GO:0030166 proteoglycan biosynthetic process 1.551608e-6
GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade 1.576446e-6
GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein 1.732979e-6
GO:0010656 negative regulation of muscle cell apoptosis 1.732979e-6
GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 1.760972e-6
GO:0002429 immune response-activating cell surface receptor signaling pathway 1.780839e-6
GO:0032765 positive regulation of mast cell cytokine production 1.807089e-6
GO:0002431 Fc receptor mediated stimulatory signaling pathway 1.807089e-6
GO:0014911 positive regulation of smooth muscle cell migration 1.869718e-6
GO:0035264 multicellular organism growth 1.922636e-6
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 1.935787e-6
GO:0007186 G-protein coupled receptor protein signaling pathway 2.226947e-6
GO:0061033 secretion by lung epithelial cell involved in lung growth 2.312492e-6
GO:0043666 regulation of phosphoprotein phosphatase activity 2.385498e-6
GO:0070663 regulation of leukocyte proliferation 2.443208e-6
GO:0051249 regulation of lymphocyte activation 2.483319e-6
GO:0010660 regulation of muscle cell apoptosis 2.915354e-6
GO:0043408 regulation of MAPKKK cascade 2.953369e-6
GO:0010591 regulation of lamellipodium assembly 3.151122e-6
GO:0009653 anatomical structure morphogenesis 3.314187e-6
GO:0051549 positive regulation of keratinocyte migration 3.431246e-6
GO:0002757 immune response-activating signal transduction 3.438734e-6
GO:0046834 lipid phosphorylation 3.444090e-6
GO:0030204 chondroitin sulfate metabolic process 3.457134e-6
GO:0042102 positive regulation of T cell proliferation 3.580083e-6
GO:0002682 regulation of immune system process 3.656089e-6
GO:0032502 developmental process 3.662947e-6
GO:0050870 positive regulation of T cell activation 3.805789e-6
GO:0030838 positive regulation of actin filament polymerization 3.873353e-6
GO:0043403 skeletal muscle tissue regeneration 4.230278e-6
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 4.321755e-6
GO:0060525 prostate glandular acinus development 4.452428e-6
GO:0044272 sulfur compound biosynthetic process 4.607628e-6
GO:0008284 positive regulation of cell proliferation 5.092414e-6
GO:0002684 positive regulation of immune system process 5.165855e-6
GO:0050670 regulation of lymphocyte proliferation 5.474542e-6
GO:0021936 regulation of cerebellar granule cell precursor proliferation 5.595771e-6
GO:0097115 neurexin clustering 5.917762e-6
GO:0007157 heterophilic cell-cell adhesion 6.050654e-6
GO:0050865 regulation of cell activation 6.084846e-6
GO:0032944 regulation of mononuclear cell proliferation 6.831884e-6
GO:0006629 lipid metabolic process 7.483850e-6
GO:0043488 regulation of mRNA stability 7.913311e-6
GO:0022612 gland morphogenesis 8.203746e-6
GO:0050679 positive regulation of epithelial cell proliferation 8.206189e-6
GO:0045321 leukocyte activation 8.541493e-6
GO:0019220 regulation of phosphate metabolic process 8.984490e-6
GO:0010676 positive regulation of cellular carbohydrate metabolic process 9.171273e-6
GO:0048583 regulation of response to stimulus 9.281159e-6
GO:0060437 lung growth 9.294888e-6
GO:0006888 ER to Golgi vesicle-mediated transport 9.595405e-6
GO:0048731 system development 1.050283e-5
GO:0002694 regulation of leukocyte activation 1.071296e-5
GO:0021940 positive regulation of cerebellar granule cell precursor proliferation 1.071568e-5
GO:0070934 CRD-mediated mRNA stabilization 1.172111e-5
GO:0022610 biological adhesion 1.195131e-5
GO:0060009 Sertoli cell development 1.256535e-5
GO:0002819 regulation of adaptive immune response 1.286866e-5
GO:0033043 regulation of organelle organization 1.297323e-5
GO:0023052 signaling 1.351589e-5
GO:0048864 stem cell development 1.407729e-5
GO:0046485 ether lipid metabolic process 1.479030e-5
GO:0046579 positive regulation of Ras protein signal transduction 1.526318e-5
GO:0043487 regulation of RNA stability 1.536178e-5
GO:0046854 phosphatidylinositol phosphorylation 1.571567e-5
GO:0042221 response to chemical stimulus 1.674663e-5
GO:0010907 positive regulation of glucose metabolic process 1.729757e-5
GO:0007155 cell adhesion 1.739609e-5
GO:0002709 regulation of T cell mediated immunity 1.760418e-5
GO:0051493 regulation of cytoskeleton organization 1.799068e-5
GO:0002762 negative regulation of myeloid leukocyte differentiation 1.829306e-5
GO:0045137 development of primary sexual characteristics 2.045121e-5
GO:0007275 multicellular organismal development 2.055919e-5
GO:0009101 glycoprotein biosynthetic process 2.088646e-5
GO:0010675 regulation of cellular carbohydrate metabolic process 2.098342e-5
GO:0006790 sulfur compound metabolic process 2.122203e-5
GO:0045776 negative regulation of blood pressure 2.128137e-5
GO:0048869 cellular developmental process 2.149540e-5
GO:0032656 regulation of interleukin-13 production 2.156986e-5
GO:0030855 epithelial cell differentiation 2.373490e-5
GO:0030203 glycosaminoglycan metabolic process 2.463981e-5
GO:0006109 regulation of carbohydrate metabolic process 2.631708e-5
GO:0046486 glycerolipid metabolic process 2.656493e-5
GO:0016337 cell-cell adhesion 2.672285e-5
GO:0032273 positive regulation of protein polymerization 2.985150e-5
GO:0000245 spliceosome assembly 3.023137e-5
GO:0048513 organ development 3.024312e-5
GO:0060426 lung vasculature development 3.384820e-5
GO:0060008 Sertoli cell differentiation 3.408284e-5
GO:0006022 aminoglycan metabolic process 3.419435e-5
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 3.531918e-5
GO:0035272 exocrine system development 3.608316e-5
GO:0060491 regulation of cell projection assembly 3.649801e-5
GO:0001101 response to acid 3.853502e-5
GO:2000177 regulation of neural precursor cell proliferation 3.888386e-5
GO:0050851 antigen receptor-mediated signaling pathway 4.243206e-5
GO:0010921 regulation of phosphatase activity 4.297330e-5
GO:0010459 negative regulation of heart rate 4.446440e-5
GO:0030104 water homeostasis 4.457426e-5
GO:0072362 regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter 4.630462e-5
GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter 4.630462e-5
GO:0051531 NFAT protein import into nucleus 4.808237e-5
GO:0009888 tissue development 4.914121e-5
GO:0010838 positive regulation of keratinocyte proliferation 5.119032e-5
GO:0050868 negative regulation of T cell activation 5.245648e-5
GO:0097120 receptor localization to synapse 5.713780e-5
GO:0072578 neurotransmitter-gated ion channel clustering 5.713780e-5
GO:0002561 basophil degranulation 5.840810e-5
GO:0065007 biological regulation 6.276767e-5
GO:0007167 enzyme linked receptor protein signaling pathway 6.530094e-5
GO:0007154 cell communication 6.690951e-5
GO:0033143 regulation of steroid hormone receptor signaling pathway 6.699499e-5
GO:0006367 transcription initiation from RNA polymerase II promoter 6.735923e-5
GO:0050867 positive regulation of cell activation 7.120598e-5
GO:0031099 regeneration 7.393229e-5
GO:0010638 positive regulation of organelle organization 7.713437e-5
GO:0010040 response to iron(II) ion 7.737313e-5
GO:0045671 negative regulation of osteoclast differentiation 8.020925e-5
GO:0008406 gonad development 8.122893e-5
GO:0043129 surfactant homeostasis 8.147963e-5
GO:0042246 tissue regeneration 8.372056e-5
GO:0045666 positive regulation of neuron differentiation 8.396401e-5
GO:0051495 positive regulation of cytoskeleton organization 8.396401e-5
GO:0048863 stem cell differentiation 8.406487e-5
GO:0070373 negative regulation of ERK1 and ERK2 cascade 8.606862e-5
GO:0001812 positive regulation of type I hypersensitivity 9.048018e-5
GO:0050794 regulation of cellular process 9.056567e-5
GO:0030154 cell differentiation 9.565487e-5
GO:0050776 regulation of immune response 9.882386e-5
GO:0046427 positive regulation of JAK-STAT cascade 1.018966e-4
GO:0007548 sex differentiation 1.047033e-4
GO:0042127 regulation of cell proliferation 1.106641e-4
GO:0090199 regulation of release of cytochrome c from mitochondria 1.122080e-4
GO:0003013 circulatory system process 1.130170e-4
GO:0014902 myotube differentiation 1.137217e-4
GO:0010627 regulation of intracellular protein kinase cascade 1.153975e-4
GO:0002706 regulation of lymphocyte mediated immunity 1.167724e-4
GO:0022008 neurogenesis 1.171806e-4
GO:0006067 ethanol metabolic process 1.189784e-4
GO:0030030 cell projection organization 1.293797e-4
GO:0006376 mRNA splice site selection 1.298602e-4
GO:0045575 basophil activation 1.313700e-4
GO:0022400 regulation of rhodopsin mediated signaling pathway 1.313700e-4
GO:0051250 negative regulation of lymphocyte activation 1.349327e-4
GO:0033026 negative regulation of mast cell apoptosis 1.373721e-4
GO:0001763 morphogenesis of a branching structure 1.433546e-4
GO:0008593 regulation of Notch signaling pathway 1.443360e-4
GO:0050789 regulation of biological process 1.521450e-4
GO:0010716 negative regulation of extracellular matrix disassembly 1.543512e-4
GO:0007165 signal transduction 1.605227e-4
GO:0016071 mRNA metabolic process 1.642128e-4
GO:0035914 skeletal muscle cell differentiation 1.670727e-4
GO:0003006 developmental process involved in reproduction 1.676989e-4
GO:0070665 positive regulation of leukocyte proliferation 1.694330e-4
GO:0001934 positive regulation of protein phosphorylation 1.784005e-4
GO:0050671 positive regulation of lymphocyte proliferation 1.785816e-4
GO:0060042 retina morphogenesis in camera-type eye 1.832514e-4
GO:0030282 bone mineralization 1.844676e-4
GO:0050678 regulation of epithelial cell proliferation 1.852124e-4
GO:0046903 secretion 1.872532e-4
GO:0031017 exocrine pancreas development 1.961661e-4
GO:0042325 regulation of phosphorylation 1.970318e-4
GO:0002696 positive regulation of leukocyte activation 2.023470e-4
GO:0000902 cell morphogenesis 2.110701e-4
GO:0030258 lipid modification 2.132687e-4
GO:0046649 lymphocyte activation 2.151423e-4
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.184950e-4
GO:0032946 positive regulation of mononuclear cell proliferation 2.213848e-4
GO:0001941 postsynaptic membrane organization 2.259008e-4
GO:0043200 response to amino acid stimulus 2.305076e-4
GO:0001775 cell activation 2.365060e-4
GO:0000398 nuclear mRNA splicing, via spliceosome 2.464659e-4
GO:0065008 regulation of biological quality 2.476853e-4
GO:0006054 N-acetylneuraminate metabolic process 2.500362e-4
GO:0051241 negative regulation of multicellular organismal process 2.531673e-4
GO:0019227 neuronal action potential propagation 2.540225e-4
GO:0032271 regulation of protein polymerization 2.557440e-4
GO:0010906 regulation of glucose metabolic process 2.791724e-4
GO:0032763 regulation of mast cell cytokine production 2.935460e-4
GO:0006352 transcription initiation, DNA-dependent 2.952661e-4
GO:0048858 cell projection morphogenesis 3.163787e-4
GO:0016080 synaptic vesicle targeting 3.248407e-4
GO:0048732 gland development 3.251855e-4
GO:0032989 cellular component morphogenesis 3.289701e-4
GO:0010740 positive regulation of intracellular protein kinase cascade 3.371078e-4
GO:0006656 phosphatidylcholine biosynthetic process 3.385297e-4
GO:0060479 lung cell differentiation 3.437532e-4
GO:0001974 blood vessel remodeling 3.446336e-4
GO:0051234 establishment of localization 3.454498e-4
GO:0033025 regulation of mast cell apoptosis 3.669311e-4
GO:0051251 positive regulation of lymphocyte activation 3.694491e-4
GO:0045663 positive regulation of myoblast differentiation 3.724863e-4
GO:0030858 positive regulation of epithelial cell differentiation 3.837319e-4
GO:0010625 positive regulation of Schwann cell proliferation 3.884809e-4
GO:0071398 cellular response to fatty acid 3.885552e-4
GO:0035418 protein localization to synapse 3.932161e-4
GO:0010837 regulation of keratinocyte proliferation 4.108561e-4
GO:0005976 polysaccharide metabolic process 4.116178e-4
GO:0070206 protein trimerization 4.150530e-4
GO:0043306 positive regulation of mast cell degranulation 4.433857e-4
GO:0019543 propionate catabolic process 4.440502e-4
GO:0090310 negative regulation of methylation-dependent chromatin silencing 4.440502e-4
GO:0030183 B cell differentiation 4.538813e-4
GO:0002703 regulation of leukocyte mediated immunity 4.621131e-4
GO:0050852 T cell receptor signaling pathway 4.732632e-4
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 4.746281e-4
GO:0001810 regulation of type I hypersensitivity 4.796439e-4
GO:0001805 positive regulation of type III hypersensitivity 4.796439e-4
GO:0000375 RNA splicing, via transesterification reactions 4.956091e-4
GO:0031399 regulation of protein modification process 5.028074e-4
GO:0016339 calcium-dependent cell-cell adhesion 5.108372e-4
GO:0003018 vascular process in circulatory system 5.124760e-4
GO:0031110 regulation of microtubule polymerization or depolymerization 5.144500e-4
GO:0032990 cell part morphogenesis 5.165227e-4
GO:0030098 lymphocyte differentiation 5.350510e-4
GO:0060695 negative regulation of cholesterol transporter activity 5.440156e-4
GO:0015759 beta-glucoside transport 5.440156e-4
GO:0002033 vasodilation by angiotensin involved in regulation of systemic arterial blood pressure 5.440156e-4
GO:0033033 negative regulation of myeloid cell apoptosis 5.441946e-4
GO:0007605 sensory perception of sound 5.542430e-4
GO:0007160 cell-matrix adhesion 5.615126e-4
GO:0001932 regulation of protein phosphorylation 5.690578e-4
GO:0002376 immune system process 5.804273e-4
GO:0031111 negative regulation of microtubule polymerization or depolymerization 5.856344e-4
GO:0010639 negative regulation of organelle organization 6.114448e-4
GO:0010741 negative regulation of intracellular protein kinase cascade 6.114875e-4
GO:0006040 amino sugar metabolic process 6.360665e-4
GO:0061138 morphogenesis of a branching epithelium 6.409698e-4
GO:0005975 carbohydrate metabolic process 6.662377e-4
GO:0006650 glycerophospholipid metabolic process 6.740546e-4
GO:0002521 leukocyte differentiation 6.835842e-4
GO:0060510 Type II pneumocyte differentiation 6.947173e-4
GO:0006903 vesicle targeting 6.947173e-4
GO:0045767 regulation of anti-apoptosis 6.951702e-4
GO:0070060 'de novo' actin filament nucleation 7.062232e-4
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound 7.091574e-4
GO:0048660 regulation of smooth muscle cell proliferation 7.160369e-4
GO:0051149 positive regulation of muscle cell differentiation 7.403761e-4
GO:0042327 positive regulation of phosphorylation 7.445335e-4
GO:0042592 homeostatic process 7.476874e-4
GO:0043302 positive regulation of leukocyte degranulation 7.498346e-4
GO:0010821 regulation of mitochondrion organization 7.542697e-4
GO:0006810 transport 7.598444e-4
GO:0032673 regulation of interleukin-4 production 7.598796e-4
GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity 7.608669e-4
GO:0008015 blood circulation 8.093870e-4
GO:0032940 secretion by cell 8.110939e-4
GO:0048745 smooth muscle tissue development 8.256437e-4
GO:0050866 negative regulation of cell activation 8.404878e-4
GO:0008016 regulation of heart contraction 8.614171e-4
GO:2000320 negative regulation of T-helper 17 cell differentiation 8.648664e-4
GO:0045017 glycerolipid biosynthetic process 8.649913e-4
GO:0060487 lung epithelial cell differentiation 8.765422e-4
GO:0050849 negative regulation of calcium-mediated signaling 9.012523e-4
GO:0019541 propionate metabolic process 9.012523e-4
GO:0048468 cell development 9.036829e-4
GO:0002695 negative regulation of leukocyte activation 9.138285e-4
GO:0001655 urogenital system development 9.200698e-4
GO:0044057 regulation of system process 9.346434e-4
GO:0015937 coenzyme A biosynthetic process 9.392368e-4
GO:0014910 regulation of smooth muscle cell migration 9.465383e-4
GO:0051716 cellular response to stimulus 9.527682e-4
GO:0048585 negative regulation of response to stimulus 9.622342e-4
GO:0010039 response to iron ion 9.796914e-4
GO:0051650 establishment of vesicle localization 9.796914e-4
GO:0060693 regulation of branching involved in salivary gland morphogenesis 9.872825e-4
GO:0071460 cellular response to cell-matrix adhesion 9.892323e-4
GO:0080134 regulation of response to stress 9.895674e-4
GO:0045840 positive regulation of mitosis 1.032396e-3
GO:0042130 negative regulation of T cell proliferation 1.032396e-3
GO:0001953 negative regulation of cell-matrix adhesion 1.058336e-3
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 1.070009e-3
GO:0070372 regulation of ERK1 and ERK2 cascade 1.080343e-3
GO:0048699 generation of neurons 1.081851e-3
GO:0046634 regulation of alpha-beta T cell activation 1.104085e-3
GO:0006398 histone mRNA 3'-end processing 1.114653e-3
GO:0002034 regulation of blood vessel size by renin-angiotensin 1.114653e-3
GO:0060537 muscle tissue development 1.163096e-3
GO:0051580 regulation of neurotransmitter uptake 1.165550e-3
GO:0016554 cytidine to uridine editing 1.203796e-3
GO:0007026 negative regulation of microtubule depolymerization 1.211116e-3
GO:0032689 negative regulation of interferon-gamma production 1.229096e-3
GO:0071378 cellular response to growth hormone stimulus 1.229744e-3
GO:0042113 B cell activation 1.243263e-3
GO:0051971 positive regulation of transmission of nerve impulse 1.245840e-3
GO:0031281 positive regulation of cyclase activity 1.247610e-3
GO:0045725 positive regulation of glycogen biosynthetic process 1.266961e-3
GO:0070327 thyroid hormone transport 1.278612e-3
GO:0050973 detection of mechanical stimulus involved in equilibrioception 1.278612e-3
GO:0018149 peptide cross-linking 1.281544e-3
GO:0097105 presynaptic membrane assembly 1.290726e-3
GO:0042946 glucoside transport 1.292706e-3
GO:0050880 regulation of blood vessel size 1.298147e-3
GO:0048871 multicellular organismal homeostasis 1.307528e-3
GO:0046636 negative regulation of alpha-beta T cell activation 1.328356e-3
GO:0051897 positive regulation of protein kinase B signaling cascade 1.338258e-3
GO:0035150 regulation of tube size 1.338258e-3
GO:0043255 regulation of carbohydrate biosynthetic process 1.377102e-3
GO:0048255 mRNA stabilization 1.406927e-3
GO:0050954 sensory perception of mechanical stimulus 1.422538e-3
GO:0050775 positive regulation of dendrite morphogenesis 1.427307e-3
GO:0060425 lung morphogenesis 1.430236e-3
GO:0030036 actin cytoskeleton organization 1.432027e-3
GO:2000505 regulation of energy homeostasis 1.444589e-3
GO:0050957 equilibrioception 1.445735e-3
GO:0045669 positive regulation of osteoblast differentiation 1.461541e-3
GO:0043467 regulation of generation of precursor metabolites and energy 1.476223e-3
GO:0044255 cellular lipid metabolic process 1.490004e-3
GO:0060291 long-term synaptic potentiation 1.510073e-3
GO:0010463 mesenchymal cell proliferation 1.535153e-3
GO:0008594 photoreceptor cell morphogenesis 1.547590e-3
GO:0045822 negative regulation of heart contraction 1.646242e-3
GO:0046326 positive regulation of glucose import 1.651104e-3
GO:0031114 regulation of microtubule depolymerization 1.651104e-3
GO:0042060 wound healing 1.651886e-3
GO:0034394 protein localization at cell surface 1.655174e-3
GO:0006397 mRNA processing 1.663352e-3
GO:2000319 regulation of T-helper 17 cell differentiation 1.671325e-3
GO:0018916 nitrobenzene metabolic process 1.671325e-3
GO:0030029 actin filament-based process 1.683581e-3
GO:0035303 regulation of dephosphorylation 1.707220e-3
GO:0060445 branching involved in salivary gland morphogenesis 1.760249e-3
GO:0003012 muscle system process 1.784023e-3
GO:0048878 chemical homeostasis 1.826405e-3
GO:0045404 positive regulation of interleukin-4 biosynthetic process 1.828384e-3
GO:0010828 positive regulation of glucose transport 1.868327e-3
GO:0032956 regulation of actin cytoskeleton organization 1.873211e-3
GO:0021559 trigeminal nerve development 1.897786e-3
GO:0033005 positive regulation of mast cell activation 1.900127e-3
GO:0051247 positive regulation of protein metabolic process 1.906370e-3
GO:0042108 positive regulation of cytokine biosynthetic process 1.921520e-3
GO:0048771 tissue remodeling 1.937665e-3
GO:0045762 positive regulation of adenylate cyclase activity 1.958199e-3
GO:0030832 regulation of actin filament length 1.960614e-3
GO:0006486 protein glycosylation 1.963779e-3
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis 2.000940e-3
GO:0023061 signal release 2.008128e-3
GO:0048534 hemopoietic or lymphoid organ development 2.008558e-3
GO:0097090 presynaptic membrane organization 2.042478e-3
GO:0030833 regulation of actin filament polymerization 2.092473e-3
GO:0034340 response to type I interferon 2.097746e-3
GO:0045768 positive regulation of anti-apoptosis 2.103430e-3
GO:0051129 negative regulation of cellular component organization 2.107023e-3
GO:0051349 positive regulation of lyase activity 2.154429e-3
GO:0034314 Arp2/3 complex-mediated actin nucleation 2.155564e-3
GO:0097091 synaptic vesicle clustering 2.163755e-3
GO:0021794 thalamus development 2.163755e-3
GO:0001878 response to yeast 2.197419e-3
GO:0045722 positive regulation of gluconeogenesis 2.219563e-3
GO:0060429 epithelium development 2.242460e-3
GO:0031646 positive regulation of neurological system process 2.301182e-3
GO:0006987 activation of signaling protein activity involved in unfolded protein response 2.374880e-3
GO:0007218 neuropeptide signaling pathway 2.440182e-3
GO:0022600 digestive system process 2.468620e-3
GO:0016079 synaptic vesicle exocytosis 2.468620e-3
GO:0031532 actin cytoskeleton reorganization 2.493154e-3
GO:0050806 positive regulation of synaptic transmission 2.509845e-3
GO:0042104 positive regulation of activated T cell proliferation 2.514500e-3
GO:0002820 negative regulation of adaptive immune response 2.517033e-3
GO:0048518 positive regulation of biological process 2.527540e-3
GO:0032970 regulation of actin filament-based process 2.591794e-3
GO:0051094 positive regulation of developmental process 2.612396e-3
GO:0043984 histone H4-K16 acetylation 2.614363e-3
GO:0007224 smoothened signaling pathway 2.666232e-3
GO:0046488 phosphatidylinositol metabolic process 2.701371e-3
GO:0046006 regulation of activated T cell proliferation 2.714033e-3
GO:0045740 positive regulation of DNA replication 2.767422e-3
GO:0045597 positive regulation of cell differentiation 2.778881e-3
GO:0046070 dGTP metabolic process 2.812242e-3
GO:0006269 DNA replication, synthesis of RNA primer 2.812242e-3
GO:0006117 acetaldehyde metabolic process 2.812242e-3
GO:0032621 interleukin-18 production 2.826291e-3
GO:0009229 thiamine diphosphate biosynthetic process 2.826291e-3
GO:0009120 deoxyribonucleoside metabolic process 2.833498e-3
GO:0032922 circadian regulation of gene expression 2.838694e-3
GO:0032355 response to estradiol stimulus 2.856209e-3
GO:0045937 positive regulation of phosphate metabolic process 2.903961e-3
GO:0070358 actin polymerization-dependent cell motility 2.910181e-3
GO:0071109 superior temporal gyrus development 2.910181e-3
GO:0060396 growth hormone receptor signaling pathway 2.917435e-3
GO:0060088 auditory receptor cell stereocilium organization 2.929462e-3
GO:0031124 mRNA 3'-end processing 2.982686e-3
GO:0060117 auditory receptor cell development 3.046065e-3
GO:0046474 glycerophospholipid biosynthetic process 3.072271e-3
GO:0008585 female gonad development 3.078886e-3
GO:0006813 potassium ion transport 3.080754e-3
GO:0007156 homophilic cell adhesion 3.081452e-3
GO:0060999 positive regulation of dendritic spine development 3.124796e-3
GO:0021536 diencephalon development 3.195773e-3
GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 3.307157e-3
GO:0048666 neuron development 3.326669e-3
GO:0010389 regulation of G2/M transition of mitotic cell cycle 3.333498e-3
GO:0051290 protein heterotetramerization 3.344059e-3
GO:0002253 activation of immune response 3.385670e-3
GO:0014065 phosphatidylinositol 3-kinase cascade 3.461218e-3
GO:0015936 coenzyme A metabolic process 3.511108e-3
GO:0060122 inner ear receptor stereocilium organization 3.516436e-3
GO:0030216 keratinocyte differentiation 3.523611e-3
GO:0061039 ovum-producing ovary development 3.535496e-3
GO:0015812 gamma-aminobutyric acid transport 3.571667e-3
GO:0050869 negative regulation of B cell activation 3.595261e-3
GO:0030097 hemopoiesis 3.624598e-3
GO:0060259 regulation of feeding behavior 3.625788e-3
GO:0090285 negative regulation of protein glycosylation in Golgi 3.827163e-3
GO:0032516 positive regulation of phosphoprotein phosphatase activity 3.851732e-3
GO:0045416 positive regulation of interleukin-8 biosynthetic process 3.872968e-3
GO:0051966 regulation of synaptic transmission, glutamatergic 3.882510e-3
GO:0048486 parasympathetic nervous system development 3.883501e-3
GO:0010648 negative regulation of cell communication 3.905450e-3
GO:0006068 ethanol catabolic process 3.914007e-3
GO:0033006 regulation of mast cell activation involved in immune response 3.921626e-3
GO:0051135 positive regulation of NK T cell activation 3.993400e-3
GO:0031401 positive regulation of protein modification process 4.061788e-3
GO:0045595 regulation of cell differentiation 4.135942e-3
GO:0030595 leukocyte chemotaxis 4.139799e-3
GO:0001706 endoderm formation 4.152594e-3
GO:0046545 development of primary female sexual characteristics 4.166217e-3
GO:0071841 cellular component organization or biogenesis at cellular level 4.174043e-3
GO:0002093 auditory receptor cell morphogenesis 4.183096e-3
GO:0023057 negative regulation of signaling 4.210575e-3
GO:0042438 melanin biosynthetic process 4.211653e-3
GO:0045667 regulation of osteoblast differentiation 4.217548e-3
GO:0050808 synapse organization 4.272437e-3
GO:0045123 cellular extravasation 4.350249e-3
GO:0030335 positive regulation of cell migration 4.375157e-3
GO:0007435 salivary gland morphogenesis 4.377343e-3
GO:0072361 regulation of glycolysis by regulation of transcription from RNA polymerase II promoter 4.392513e-3
GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter 4.392513e-3
GO:0045650 negative regulation of macrophage differentiation 4.392513e-3
GO:0016553 base conversion or substitution editing 4.392513e-3
GO:0060235 lens induction in camera-type eye 4.400009e-3
GO:0002052 positive regulation of neuroblast proliferation 4.417572e-3
GO:0048641 regulation of skeletal muscle tissue development 4.421208e-3
GO:0071842 cellular component organization at cellular level 4.427345e-3
GO:0007492 endoderm development 4.466221e-3
GO:0061304 retinal blood vessel morphogenesis 4.487483e-3
GO:0045168 cell-cell signaling involved in cell fate commitment 4.501024e-3