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Novel motif:96

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name:motif96_TKNTTCTGTCTN

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0003008 system process 2.089892e-21
GO:0023052 signaling 4.976401e-18
GO:0032501 multicellular organismal process 4.421862e-17
GO:0007154 cell communication 4.618176e-17
GO:0050896 response to stimulus 7.892871e-16
GO:0051716 cellular response to stimulus 1.265020e-14
GO:0006955 immune response 2.509326e-14
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 5.154525e-14
GO:0007165 signal transduction 1.309458e-13
GO:0050877 neurological system process 2.746382e-13
GO:0007186 G-protein coupled receptor protein signaling pathway 5.672003e-13
GO:0002376 immune system process 7.036346e-13
GO:0042137 sequestering of neurotransmitter 7.537312e-13
GO:0006950 response to stress 1.419313e-12
GO:0042221 response to chemical stimulus 1.670595e-12
GO:0007166 cell surface receptor linked signaling pathway 1.727098e-12
GO:0007268 synaptic transmission 1.759069e-12
GO:0019226 transmission of nerve impulse 3.410145e-12
GO:0006952 defense response 8.880224e-12
GO:0051592 response to calcium ion 1.702873e-11
GO:0002694 regulation of leukocyte activation 5.379327e-11
GO:0007267 cell-cell signaling 5.381554e-11
GO:0002861 regulation of inflammatory response to antigenic stimulus 8.693295e-11
GO:0010466 negative regulation of peptidase activity 9.743161e-11
GO:0002891 positive regulation of immunoglobulin mediated immune response 1.854656e-10
GO:0051336 regulation of hydrolase activity 1.865434e-10
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 4.710089e-10
GO:0002768 immune response-regulating cell surface receptor signaling pathway 4.867063e-10
GO:0052547 regulation of peptidase activity 5.331731e-10
GO:0002696 positive regulation of leukocyte activation 6.181913e-10
GO:0009611 response to wounding 8.221721e-10
GO:0012501 programmed cell death 8.667772e-10
GO:0016525 negative regulation of angiogenesis 8.979586e-10
GO:0043537 negative regulation of blood vessel endothelial cell migration 9.430412e-10
GO:0050865 regulation of cell activation 9.706182e-10
GO:0006915 apoptosis 1.014817e-9
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1.503555e-9
GO:0002885 positive regulation of hypersensitivity 3.796770e-9
GO:0001775 cell activation 4.250430e-9
GO:0043154 negative regulation of caspase activity 4.596179e-9
GO:0051346 negative regulation of hydrolase activity 5.341243e-9
GO:0043652 engulfment of apoptotic cell 5.614697e-9
GO:0010754 negative regulation of cGMP-mediated signaling 5.614697e-9
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 5.614697e-9
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 5.614697e-9
GO:0010751 negative regulation of nitric oxide mediated signal transduction 5.614697e-9
GO:0006936 muscle contraction 5.880251e-9
GO:0032655 regulation of interleukin-12 production 8.866283e-9
GO:0010035 response to inorganic substance 8.928416e-9
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 9.758465e-9
GO:0040040 thermosensory behavior 1.013545e-8
GO:0002883 regulation of hypersensitivity 1.103715e-8
GO:0010942 positive regulation of cell death 1.124280e-8
GO:0002764 immune response-regulating signaling pathway 1.162093e-8
GO:0050867 positive regulation of cell activation 1.485544e-8
GO:0015671 oxygen transport 1.579737e-8
GO:0070265 necrotic cell death 1.707096e-8
GO:0016265 death 1.820940e-8
GO:0007616 long-term memory 2.090943e-8
GO:0008219 cell death 2.239576e-8
GO:0002922 positive regulation of humoral immune response 2.277389e-8
GO:0010763 positive regulation of fibroblast migration 2.294939e-8
GO:0032891 negative regulation of organic acid transport 2.401980e-8
GO:0042534 regulation of tumor necrosis factor biosynthetic process 2.459473e-8
GO:0050680 negative regulation of epithelial cell proliferation 2.467376e-8
GO:0009266 response to temperature stimulus 2.480905e-8
GO:0002740 negative regulation of cytokine secretion involved in immune response 2.529210e-8
GO:0007431 salivary gland development 2.723897e-8
GO:0007163 establishment or maintenance of cell polarity 2.877369e-8
GO:0052548 regulation of endopeptidase activity 3.451481e-8
GO:0032026 response to magnesium ion 3.742953e-8
GO:0001798 positive regulation of type IIa hypersensitivity 4.321201e-8
GO:0030185 nitric oxide transport 4.764011e-8
GO:0043065 positive regulation of apoptosis 6.431898e-8
GO:0070613 regulation of protein processing 7.861664e-8
GO:0032800 receptor biosynthetic process 8.913196e-8
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 8.914603e-8
GO:0002429 immune response-activating cell surface receptor signaling pathway 1.090427e-7
GO:0002604 regulation of dendritic cell antigen processing and presentation 1.261650e-7
GO:0006917 induction of apoptosis 1.329450e-7
GO:0065007 biological regulation 1.454935e-7
GO:0002920 regulation of humoral immune response 1.791541e-7
GO:0007249 I-kappaB kinase/NF-kappaB cascade 1.959169e-7
GO:0061048 negative regulation of branching involved in lung morphogenesis 2.108943e-7
GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly 2.108943e-7
GO:0030011 maintenance of cell polarity 2.120960e-7
GO:0034616 response to laminar fluid shear stress 2.154791e-7
GO:0012502 induction of programmed cell death 2.157222e-7
GO:0010596 negative regulation of endothelial cell migration 2.472627e-7
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 2.518359e-7
GO:0032369 negative regulation of lipid transport 2.697119e-7
GO:0006968 cellular defense response 2.896151e-7
GO:0007612 learning 2.918077e-7
GO:0009408 response to heat 3.015429e-7
GO:0050789 regulation of biological process 3.379857e-7
GO:0050851 antigen receptor-mediated signaling pathway 3.534778e-7
GO:2000116 regulation of cysteine-type endopeptidase activity 3.564586e-7
GO:0015669 gas transport 3.593918e-7
GO:0050778 positive regulation of immune response 3.674792e-7
GO:0045994 positive regulation of translational initiation by iron 3.852589e-7
GO:0002037 negative regulation of L-glutamate transport 3.852589e-7
GO:0050729 positive regulation of inflammatory response 3.977811e-7
GO:0043068 positive regulation of programmed cell death 4.018144e-7
GO:0043032 positive regulation of macrophage activation 4.218992e-7
GO:0051023 regulation of immunoglobulin secretion 4.315422e-7
GO:0006911 phagocytosis, engulfment 4.613942e-7
GO:0034097 response to cytokine stimulus 4.872236e-7
GO:0042981 regulation of apoptosis 4.921808e-7
GO:0045087 innate immune response 5.254680e-7
GO:0071675 regulation of mononuclear cell migration 5.660169e-7
GO:0051017 actin filament bundle assembly 5.812070e-7
GO:0032943 mononuclear cell proliferation 5.900580e-7
GO:0010836 negative regulation of protein ADP-ribosylation 5.974710e-7
GO:0006813 potassium ion transport 6.074224e-7
GO:0002757 immune response-activating signal transduction 6.243858e-7
GO:0002684 positive regulation of immune system process 6.949516e-7
GO:0070301 cellular response to hydrogen peroxide 7.418697e-7
GO:0051533 positive regulation of NFAT protein import into nucleus 7.831529e-7
GO:0010755 regulation of plasminogen activation 8.127222e-7
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis 8.776367e-7
GO:0032695 negative regulation of interleukin-12 production 9.584812e-7
GO:0034762 regulation of transmembrane transport 9.641472e-7
GO:0051895 negative regulation of focal adhesion assembly 9.653571e-7
GO:0002449 lymphocyte mediated immunity 9.846496e-7
GO:0007435 salivary gland morphogenesis 1.014661e-6
GO:0010033 response to organic substance 1.032407e-6
GO:0045948 positive regulation of translational initiation 1.062186e-6
GO:0002544 chronic inflammatory response 1.100909e-6
GO:0035418 protein localization to synapse 1.102935e-6
GO:0050892 intestinal absorption 1.138525e-6
GO:0015698 inorganic anion transport 1.225244e-6
GO:0010941 regulation of cell death 1.244268e-6
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 1.276415e-6
GO:0009628 response to abiotic stimulus 1.278869e-6
GO:0046600 negative regulation of centriole replication 1.281349e-6
GO:0006447 regulation of translational initiation by iron 1.375603e-6
GO:0009617 response to bacterium 1.381087e-6
GO:0071310 cellular response to organic substance 1.452601e-6
GO:0010759 positive regulation of macrophage chemotaxis 1.542775e-6
GO:0071844 cellular component assembly at cellular level 1.543147e-6
GO:0051897 positive regulation of protein kinase B signaling cascade 1.599838e-6
GO:0046651 lymphocyte proliferation 1.907282e-6
GO:0022612 gland morphogenesis 1.972530e-6
GO:0031349 positive regulation of defense response 1.996439e-6
GO:0032570 response to progesterone stimulus 2.119682e-6
GO:0043067 regulation of programmed cell death 2.244543e-6
GO:0002577 regulation of antigen processing and presentation 2.396059e-6
GO:0001666 response to hypoxia 2.478485e-6
GO:0010757 negative regulation of plasminogen activation 2.507603e-6
GO:0010758 regulation of macrophage chemotaxis 2.549567e-6
GO:0070661 leukocyte proliferation 2.565457e-6
GO:0002253 activation of immune response 2.594078e-6
GO:0002889 regulation of immunoglobulin mediated immune response 2.716353e-6
GO:0071345 cellular response to cytokine stimulus 2.771087e-6
GO:0051249 regulation of lymphocyte activation 2.817480e-6
GO:0032914 positive regulation of transforming growth factor beta1 production 2.838250e-6
GO:0002712 regulation of B cell mediated immunity 3.119374e-6
GO:0070887 cellular response to chemical stimulus 3.284172e-6
GO:0010038 response to metal ion 3.415523e-6
GO:0032103 positive regulation of response to external stimulus 3.602473e-6
GO:0016064 immunoglobulin mediated immune response 3.695864e-6
GO:0051606 detection of stimulus 4.042260e-6
GO:0050860 negative regulation of T cell receptor signaling pathway 4.076524e-6
GO:0003009 skeletal muscle contraction 4.380778e-6
GO:0065009 regulation of molecular function 4.381722e-6
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 4.381792e-6
GO:0002250 adaptive immune response 4.419745e-6
GO:0002675 positive regulation of acute inflammatory response 4.651826e-6
GO:0043030 regulation of macrophage activation 4.737080e-6
GO:0031508 centromeric heterochromatin formation 4.779515e-6
GO:0070482 response to oxygen levels 4.839373e-6
GO:0042742 defense response to bacterium 4.881928e-6
GO:0001819 positive regulation of cytokine production 4.884802e-6
GO:0071805 potassium ion transmembrane transport 5.013177e-6
GO:0051099 positive regulation of binding 5.222296e-6
GO:0050678 regulation of epithelial cell proliferation 5.260056e-6
GO:0043049 otic placode formation 5.832023e-6
GO:0050856 regulation of T cell receptor signaling pathway 6.487473e-6
GO:0018095 protein polyglutamylation 6.530890e-6
GO:0035272 exocrine system development 6.745652e-6
GO:0051707 response to other organism 6.886840e-6
GO:0031295 T cell costimulation 6.892089e-6
GO:0001970 positive regulation of activation of membrane attack complex 6.970397e-6
GO:0032502 developmental process 7.657012e-6
GO:0051953 negative regulation of amine transport 7.814977e-6
GO:0044341 sodium-dependent phosphate transport 7.894737e-6
GO:0051798 positive regulation of hair follicle development 7.908688e-6
GO:0009435 NAD biosynthetic process 8.023227e-6
GO:0006769 nicotinamide metabolic process 8.046764e-6
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway 8.105362e-6
GO:0050852 T cell receptor signaling pathway 8.202776e-6
GO:0051896 regulation of protein kinase B signaling cascade 8.272271e-6
GO:0007620 copulation 8.568834e-6
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 8.922110e-6
GO:0018149 peptide cross-linking 9.144292e-6
GO:0071803 positive regulation of podosome assembly 1.004808e-5
GO:0002576 platelet degranulation 1.014610e-5
GO:0032205 negative regulation of telomere maintenance 1.022218e-5
GO:0050794 regulation of cellular process 1.121158e-5
GO:0051704 multi-organism process 1.156664e-5
GO:0031110 regulation of microtubule polymerization or depolymerization 1.180556e-5
GO:0002739 regulation of cytokine secretion involved in immune response 1.200647e-5
GO:0019363 pyridine nucleotide biosynthetic process 1.207848e-5
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.235315e-5
GO:0042744 hydrogen peroxide catabolic process 1.247175e-5
GO:0034330 cell junction organization 1.261640e-5
GO:0009187 cyclic nucleotide metabolic process 1.329994e-5
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 1.330743e-5
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 1.347404e-5
GO:0051918 negative regulation of fibrinolysis 1.448682e-5
GO:0002426 immunoglobulin production in mucosal tissue 1.450824e-5
GO:0009214 cyclic nucleotide catabolic process 1.453189e-5
GO:0006954 inflammatory response 1.472997e-5
GO:0010955 negative regulation of protein processing 1.526453e-5
GO:0051049 regulation of transport 1.638304e-5
GO:0009719 response to endogenous stimulus 1.659830e-5
GO:0003012 muscle system process 1.686781e-5
GO:0019674 NAD metabolic process 1.711833e-5
GO:0019724 B cell mediated immunity 1.726713e-5
GO:0002718 regulation of cytokine production involved in immune response 1.775543e-5
GO:0048856 anatomical structure development 1.791749e-5
GO:0009820 alkaloid metabolic process 1.880880e-5
GO:0002036 regulation of L-glutamate transport 1.882445e-5
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 1.921587e-5
GO:0046548 retinal rod cell development 1.936243e-5
GO:0009725 response to hormone stimulus 2.011069e-5
GO:0050727 regulation of inflammatory response 2.033345e-5
GO:0015705 iodide transport 2.107172e-5
GO:0042060 wound healing 2.112611e-5
GO:0046058 cAMP metabolic process 2.116029e-5
GO:0032438 melanosome organization 2.164273e-5
GO:0051293 establishment of spindle localization 2.184730e-5
GO:0031663 lipopolysaccharide-mediated signaling pathway 2.234571e-5
GO:0009607 response to biotic stimulus 2.235708e-5
GO:0051251 positive regulation of lymphocyte activation 2.249044e-5
GO:0071622 regulation of granulocyte chemotaxis 2.279874e-5
GO:0006941 striated muscle contraction 2.284558e-5
GO:0031347 regulation of defense response 2.331245e-5
GO:0032211 negative regulation of telomere maintenance via telomerase 2.358541e-5
GO:0043114 regulation of vascular permeability 2.406686e-5
GO:0042094 interleukin-2 biosynthetic process 2.513603e-5
GO:0051917 regulation of fibrinolysis 2.528633e-5
GO:0046903 secretion 2.583062e-5
GO:0008156 negative regulation of DNA replication 2.748284e-5
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 2.798369e-5
GO:0050830 defense response to Gram-positive bacterium 2.801728e-5
GO:0034329 cell junction assembly 2.944988e-5
GO:0044085 cellular component biogenesis 3.043340e-5
GO:0009268 response to pH 3.255315e-5
GO:0017157 regulation of exocytosis 3.274741e-5
GO:0006820 anion transport 3.301045e-5
GO:0045071 negative regulation of viral genome replication 3.439769e-5
GO:0048513 organ development 3.466971e-5
GO:0050854 regulation of antigen receptor-mediated signaling pathway 3.470804e-5
GO:0009593 detection of chemical stimulus 3.612889e-5
GO:0048545 response to steroid hormone stimulus 3.713726e-5
GO:0019359 nicotinamide nucleotide biosynthetic process 3.736173e-5
GO:0031646 positive regulation of neurological system process 3.810531e-5
GO:0002443 leukocyte mediated immunity 3.945059e-5
GO:0050798 activated T cell proliferation 4.043252e-5
GO:0007044 cell-substrate junction assembly 4.066280e-5
GO:0007091 mitotic metaphase/anaphase transition 4.129103e-5
GO:0034198 cellular response to amino acid starvation 4.195463e-5
GO:0001937 negative regulation of endothelial cell proliferation 4.197920e-5
GO:0006198 cAMP catabolic process 4.323625e-5
GO:0071034 CUT catabolic process 4.567762e-5
GO:0050776 regulation of immune response 4.777282e-5
GO:0072387 flavin adenine dinucleotide metabolic process 4.907494e-5
GO:0032940 secretion by cell 5.079832e-5
GO:0070884 regulation of calcineurin-NFAT signaling pathway 5.339730e-5
GO:0032844 regulation of homeostatic process 5.343993e-5
GO:0035710 CD4-positive, alpha-beta T cell activation 5.363543e-5
GO:0008588 release of cytoplasmic sequestered NF-kappaB 5.386621e-5
GO:0015672 monovalent inorganic cation transport 5.608666e-5
GO:0002683 negative regulation of immune system process 5.613209e-5
GO:0031444 slow-twitch skeletal muscle fiber contraction 5.654451e-5
GO:0060557 positive regulation of vitamin D biosynthetic process 5.697166e-5
GO:0043623 cellular protein complex assembly 5.702519e-5
GO:0051345 positive regulation of hydrolase activity 5.768014e-5
GO:0034333 adherens junction assembly 5.922790e-5
GO:0002682 regulation of immune system process 6.037530e-5
GO:0048753 pigment granule organization 6.100472e-5
GO:0051797 regulation of hair follicle development 6.132648e-5
GO:0030574 collagen catabolic process 6.132648e-5
GO:0045324 late endosome to vacuole transport 6.253998e-5
GO:0071321 cellular response to cGMP 6.423204e-5
GO:0009125 nucleoside monophosphate catabolic process 6.424991e-5
GO:0030168 platelet activation 6.447302e-5
GO:0051971 positive regulation of transmission of nerve impulse 6.496633e-5
GO:0002700 regulation of production of molecular mediator of immune response 6.518452e-5
GO:0045059 positive thymic T cell selection 6.738709e-5
GO:0006887 exocytosis 6.812300e-5
GO:0007611 learning or memory 6.841436e-5
GO:0071229 cellular response to acid 6.874702e-5
GO:0043535 regulation of blood vessel endothelial cell migration 7.009862e-5
GO:0043367 CD4-positive, alpha-beta T cell differentiation 7.223748e-5
GO:0051053 negative regulation of DNA metabolic process 7.423877e-5
GO:0006682 galactosylceramide biosynthetic process 7.624630e-5
GO:0006811 ion transport 7.684406e-5
GO:0032320 positive regulation of Ras GTPase activity 8.002178e-5
GO:0048732 gland development 8.092114e-5
GO:0009743 response to carbohydrate stimulus 8.114602e-5
GO:0030862 positive regulation of polarized epithelial cell differentiation 8.151022e-5
GO:0050907 detection of chemical stimulus involved in sensory perception 8.163854e-5
GO:0051893 regulation of focal adhesion assembly 8.286746e-5
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 8.351928e-5
GO:0002886 regulation of myeloid leukocyte mediated immunity 8.359955e-5
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate 8.366068e-5
GO:0046724 oxalic acid secretion 8.366068e-5
GO:0007275 multicellular organismal development 8.556967e-5
GO:0042986 positive regulation of amyloid precursor protein biosynthetic process 8.670010e-5
GO:0070417 cellular response to cold 8.844247e-5
GO:0001909 leukocyte mediated cytotoxicity 8.884832e-5
GO:0002673 regulation of acute inflammatory response 9.113329e-5
GO:0043353 enucleate erythrocyte differentiation 9.170681e-5
GO:0060341 regulation of cellular localization 9.254571e-5
GO:0060555 induction of necroptosis by extracellular signals 9.254800e-5
GO:0007155 cell adhesion 9.362782e-5
GO:0007596 blood coagulation 9.507383e-5
GO:0043462 regulation of ATPase activity 9.535178e-5
GO:0030889 negative regulation of B cell proliferation 9.548532e-5
GO:0050710 negative regulation of cytokine secretion 9.945464e-5
GO:0007202 activation of phospholipase C activity 1.034591e-4
GO:0014047 glutamate secretion 1.140485e-4
GO:0050911 detection of chemical stimulus involved in sensory perception of smell 1.149047e-4
GO:0051549 positive regulation of keratinocyte migration 1.169166e-4
GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade 1.175426e-4
GO:0070305 response to cGMP 1.248232e-4
GO:0060627 regulation of vesicle-mediated transport 1.248414e-4
GO:0030888 regulation of B cell proliferation 1.257529e-4
GO:0048584 positive regulation of response to stimulus 1.266887e-4
GO:0022607 cellular component assembly 1.338573e-4
GO:0045684 positive regulation of epidermis development 1.349418e-4
GO:0042267 natural killer cell mediated cytotoxicity 1.350188e-4
GO:0035721 intraflagellar retrograde transport 1.355830e-4
GO:0016560 protein import into peroxisome matrix, docking 1.355830e-4
GO:0042035 regulation of cytokine biosynthetic process 1.363223e-4
GO:0051956 negative regulation of amino acid transport 1.378053e-4
GO:0045321 leukocyte activation 1.404611e-4
GO:0007599 hemostasis 1.413716e-4
GO:0002678 positive regulation of chronic inflammatory response 1.415720e-4
GO:0034763 negative regulation of transmembrane transport 1.420816e-4
GO:0007253 cytoplasmic sequestering of NF-kappaB 1.439843e-4
GO:2000379 positive regulation of reactive oxygen species metabolic process 1.449292e-4
GO:0001817 regulation of cytokine production 1.482041e-4
GO:0043536 positive regulation of blood vessel endothelial cell migration 1.495126e-4
GO:0015816 glycine transport 1.565961e-4
GO:0032092 positive regulation of protein binding 1.572191e-4
GO:0032375 negative regulation of cholesterol transport 1.583800e-4
GO:0006733 oxidoreduction coenzyme metabolic process 1.621160e-4
GO:0045796 negative regulation of intestinal cholesterol absorption 1.682896e-4
GO:0010949 negative regulation of intestinal phytosterol absorption 1.682896e-4
GO:0006821 chloride transport 1.688784e-4
GO:0001957 intramembranous ossification 1.703088e-4
GO:0045069 regulation of viral genome replication 1.708594e-4
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 1.721661e-4
GO:0032876 negative regulation of DNA endoreduplication 1.723679e-4
GO:0048739 cardiac muscle fiber development 1.758848e-4
GO:0009888 tissue development 1.766588e-4
GO:0002708 positive regulation of lymphocyte mediated immunity 1.835753e-4
GO:0010594 regulation of endothelial cell migration 1.868627e-4
GO:0009749 response to glucose stimulus 1.889260e-4
GO:0071230 cellular response to amino acid stimulus 1.960427e-4
GO:0002676 regulation of chronic inflammatory response 1.991271e-4
GO:0003018 vascular process in circulatory system 2.022914e-4
GO:0030036 actin cytoskeleton organization 2.048427e-4
GO:0051292 nuclear pore complex assembly 2.052128e-4
GO:0044093 positive regulation of molecular function 2.080556e-4
GO:0010863 positive regulation of phospholipase C activity 2.107620e-4
GO:0051046 regulation of secretion 2.155224e-4
GO:0032890 regulation of organic acid transport 2.175386e-4
GO:0031915 positive regulation of synaptic plasticity 2.183102e-4
GO:0034614 cellular response to reactive oxygen species 2.209370e-4
GO:0051151 negative regulation of smooth muscle cell differentiation 2.215836e-4
GO:0035235 ionotropic glutamate receptor signaling pathway 2.244612e-4
GO:0030335 positive regulation of cell migration 2.252659e-4
GO:0001812 positive regulation of type I hypersensitivity 2.298543e-4
GO:0008624 induction of apoptosis by extracellular signals 2.300457e-4
GO:0050790 regulation of catalytic activity 2.310353e-4
GO:0007050 cell cycle arrest 2.345686e-4
GO:0030004 cellular monovalent inorganic cation homeostasis 2.362121e-4
GO:0010350 cellular response to magnesium starvation 2.365168e-4
GO:0048534 hemopoietic or lymphoid organ development 2.392141e-4
GO:0030029 actin filament-based process 2.435623e-4
GO:0048731 system development 2.498506e-4
GO:0021987 cerebral cortex development 2.526075e-4
GO:0071636 positive regulation of transforming growth factor beta production 2.529322e-4
GO:0034205 beta-amyloid formation 2.535320e-4
GO:0034284 response to monosaccharide stimulus 2.556827e-4
GO:0008625 induction of apoptosis via death domain receptors 2.622914e-4
GO:2000147 positive regulation of cell motility 2.629831e-4
GO:0050806 positive regulation of synaptic transmission 2.634425e-4
GO:0007131 reciprocal meiotic recombination 2.646485e-4
GO:0007527 adult somatic muscle development 2.686851e-4
GO:0051240 positive regulation of multicellular organismal process 2.730722e-4
GO:0007320 insemination 2.731728e-4
GO:0040017 positive regulation of locomotion 2.771302e-4
GO:0048518 positive regulation of biological process 2.787383e-4
GO:0042462 eye photoreceptor cell development 2.856556e-4
GO:0007098 centrosome cycle 2.890868e-4
GO:0032908 regulation of transforming growth factor beta1 production 2.906347e-4
GO:0010595 positive regulation of endothelial cell migration 2.946372e-4
GO:0009746 response to hexose stimulus 3.063343e-4
GO:0070507 regulation of microtubule cytoskeleton organization 3.132423e-4
GO:0051098 regulation of binding 3.171256e-4
GO:0010954 positive regulation of protein processing 3.226312e-4
GO:0032879 regulation of localization 3.282631e-4
GO:0050878 regulation of body fluid levels 3.326065e-4
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 3.354070e-4
GO:0070845 polyubiquitinated misfolded protein transport 3.406275e-4
GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 3.431164e-4
GO:0040001 establishment of mitotic spindle localization 3.450050e-4
GO:0042461 photoreceptor cell development 3.486656e-4
GO:0000132 establishment of mitotic spindle orientation 3.528695e-4
GO:0043932 ossification involved in bone remodeling 3.550570e-4
GO:0008306 associative learning 3.597626e-4
GO:0033864 positive regulation of NAD(P)H oxidase activity 3.663017e-4
GO:0050890 cognition 3.685367e-4
GO:0006111 regulation of gluconeogenesis 3.737399e-4
GO:0017158 regulation of calcium ion-dependent exocytosis 3.774612e-4
GO:0050709 negative regulation of protein secretion 3.784125e-4
GO:0022600 digestive system process 3.820264e-4
GO:0003051 angiotensin-mediated drinking behavior 3.901337e-4
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 4.020274e-4
GO:0007174 epidermal growth factor catabolic process 4.085200e-4
GO:0065008 regulation of biological quality 4.096864e-4
GO:0009612 response to mechanical stimulus 4.144804e-4
GO:0042438 melanin biosynthetic process 4.176455e-4
GO:0046549 retinal cone cell development 4.256440e-4
GO:0030449 regulation of complement activation 4.275779e-4
GO:0050906 detection of stimulus involved in sensory perception 4.277091e-4
GO:0007250 activation of NF-kappaB-inducing kinase activity 4.435263e-4
GO:0042036 negative regulation of cytokine biosynthetic process 4.491307e-4
GO:0034014 response to triglyceride 4.584002e-4
GO:0032886 regulation of microtubule-based process 4.647088e-4
GO:0051297 centrosome organization 4.724123e-4
GO:0046325 negative regulation of glucose import 4.728171e-4
GO:0097120 receptor localization to synapse 4.817412e-4
GO:0072578 neurotransmitter-gated ion channel clustering 4.817412e-4
GO:0002282 microglial cell activation involved in immune response 4.817412e-4
GO:0030100 regulation of endocytosis 4.867968e-4
GO:0007126 meiosis 4.883327e-4
GO:0006621 protein retention in ER lumen 4.967647e-4
GO:0046599 regulation of centriole replication 5.005465e-4
GO:0009605 response to external stimulus 5.011322e-4
GO:0009253 peptidoglycan catabolic process 5.077764e-4
GO:0050863 regulation of T cell activation 5.093911e-4
GO:0060693 regulation of branching involved in salivary gland morphogenesis 5.098631e-4
GO:0071460 cellular response to cell-matrix adhesion 5.104118e-4
GO:0046687 response to chromate 5.104118e-4
GO:0033986 response to methanol 5.104118e-4
GO:0052509 positive regulation by symbiont of host defense response 5.125573e-4
GO:0048522 positive regulation of cellular process 5.228388e-4
GO:0007127 meiosis I 5.250013e-4
GO:0048489 synaptic vesicle transport 5.266633e-4
GO:2000679 positive regulation of transcription regulatory region DNA binding 5.268837e-4
GO:0032680 regulation of tumor necrosis factor production 5.277537e-4
GO:0019221 cytokine-mediated signaling pathway 5.288598e-4
GO:0016049 cell growth 5.316430e-4
GO:0043117 positive regulation of vascular permeability 5.493893e-4
GO:0050864 regulation of B cell activation 5.569197e-4
GO:0042938 dipeptide transport 5.573433e-4
GO:0043269 regulation of ion transport 5.581665e-4
GO:0042098 T cell proliferation 5.636974e-4
GO:0031641 regulation of myelination 5.648024e-4
GO:2000739 regulation of mesenchymal stem cell differentiation 5.662775e-4
GO:0044130 negative regulation of growth of symbiont in host 5.890802e-4
GO:0045104 intermediate filament cytoskeleton organization 5.939632e-4
GO:2001021 negative regulation of response to DNA damage stimulus 5.984679e-4
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity 6.111150e-4
GO:0051685 maintenance of ER location 6.119373e-4
GO:0042542 response to hydrogen peroxide 6.171652e-4
GO:0071495 cellular response to endogenous stimulus 6.199087e-4
GO:0031581 hemidesmosome assembly 6.341711e-4
GO:0032252 secretory granule localization 6.507410e-4
GO:0010951 negative regulation of endopeptidase activity 6.508611e-4
GO:2000617 positive regulation of histone H3-K9 acetylation 6.515658e-4
GO:2000620 positive regulation of histone H4-K16 acetylation 6.515658e-4
GO:0070512 positive regulation of histone H4-K20 methylation 6.515658e-4
GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response 6.515658e-4
GO:0007586 digestion 6.704579e-4
GO:0006959 humoral immune response 6.757091e-4
GO:0032845 negative regulation of homeostatic process 6.786974e-4
GO:0042743 hydrogen peroxide metabolic process 6.793820e-4
GO:0043277 apoptotic cell clearance 6.887445e-4
GO:0010535 positive regulation of activation of JAK2 kinase activity 6.977045e-4
GO:0051298 centrosome duplication 6.997646e-4
GO:0007522 visceral muscle development 7.017252e-4
GO:0080134 regulation of response to stress 7.049753e-4
GO:0042982 amyloid precursor protein metabolic process 7.123995e-4
GO:2000463 positive regulation of excitatory postsynaptic membrane potential 7.208484e-4
GO:0010560 positive regulation of glycoprotein biosynthetic process 7.209464e-4
GO:0060040 retinal bipolar neuron differentiation 7.263066e-4
GO:0023051 regulation of signaling 7.508473e-4
GO:0051272 positive regulation of cellular component movement 7.582854e-4
GO:0045760 positive regulation of action potential 7.598316e-4
GO:0000302 response to reactive oxygen species 7.605195e-4
GO:0032101 regulation of response to external stimulus 7.613388e-4
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 7.744805e-4
GO:0010518 positive regulation of phospholipase activity 7.765431e-4


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0016579 protein deubiquitination 9.873670e-17
GO:0070646 protein modification by small protein removal 1.849014e-12
GO:0007154 cell communication 1.954968e-11
GO:0023052 signaling 5.835738e-11
GO:0002376 immune system process 5.872003e-11
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 1.686132e-10
GO:0007166 cell surface receptor linked signaling pathway 1.972984e-10
GO:0065008 regulation of biological quality 3.748963e-10
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 6.743788e-10
GO:0002521 leukocyte differentiation 9.803970e-10
GO:0055072 iron ion homeostasis 2.123397e-9
GO:0007165 signal transduction 2.263863e-9
GO:0006826 iron ion transport 3.096817e-9
GO:0030097 hemopoiesis 4.926917e-9
GO:0001775 cell activation 6.480125e-9
GO:0010627 regulation of intracellular protein kinase cascade 6.828859e-9
GO:0048534 hemopoietic or lymphoid organ development 7.688153e-9
GO:0060457 negative regulation of digestive system process 9.309451e-9
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 1.688561e-8
GO:0002520 immune system development 1.881500e-8
GO:0043620 regulation of DNA-dependent transcription in response to stress 1.961551e-8
GO:0014012 peripheral nervous system axon regeneration 2.385304e-8
GO:0046427 positive regulation of JAK-STAT cascade 2.626559e-8
GO:0050896 response to stimulus 2.936177e-8
GO:0010740 positive regulation of intracellular protein kinase cascade 3.451437e-8
GO:0009611 response to wounding 3.582585e-8
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 5.268621e-8
GO:0051385 response to mineralocorticoid stimulus 5.553823e-8
GO:0046425 regulation of JAK-STAT cascade 6.061256e-8
GO:0006950 response to stress 9.555051e-8
GO:0055080 cation homeostasis 1.004527e-7
GO:0042110 T cell activation 1.065711e-7
GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 1.143718e-7
GO:0006879 cellular iron ion homeostasis 1.260836e-7
GO:0045796 negative regulation of intestinal cholesterol absorption 1.303958e-7
GO:0010949 negative regulation of intestinal phytosterol absorption 1.303958e-7
GO:0032946 positive regulation of mononuclear cell proliferation 1.336751e-7
GO:0030217 T cell differentiation 1.367422e-7
GO:0045321 leukocyte activation 1.607891e-7
GO:0070665 positive regulation of leukocyte proliferation 1.675427e-7
GO:0055065 metal ion homeostasis 2.191658e-7
GO:0048878 chemical homeostasis 2.442867e-7
GO:0051412 response to corticosterone stimulus 2.756304e-7
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 3.126477e-7
GO:0050671 positive regulation of lymphocyte proliferation 3.358793e-7
GO:0006811 ion transport 4.240414e-7
GO:0030098 lymphocyte differentiation 4.455332e-7
GO:0030104 water homeostasis 5.624734e-7
GO:0051716 cellular response to stimulus 8.869627e-7
GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein 9.710315e-7
GO:0042102 positive regulation of T cell proliferation 1.031435e-6
GO:0046649 lymphocyte activation 1.378830e-6
GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein 1.711680e-6
GO:0061308 cardiac neural crest cell development involved in heart development 1.819353e-6
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 1.911340e-6
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 1.982053e-6
GO:0006508 proteolysis 2.434389e-6
GO:0065007 biological regulation 2.652102e-6
GO:0009185 ribonucleoside diphosphate metabolic process 3.211927e-6
GO:0042493 response to drug 3.213142e-6
GO:0051384 response to glucocorticoid stimulus 3.246284e-6
GO:0042592 homeostatic process 3.463325e-6
GO:0048731 system development 4.120769e-6
GO:0035904 aorta development 4.743681e-6
GO:0060442 branching involved in prostate gland morphogenesis 5.176086e-6
GO:0045329 carnitine biosynthetic process 5.497734e-6
GO:0003008 system process 5.995478e-6
GO:0050801 ion homeostasis 6.110525e-6
GO:0007007 inner mitochondrial membrane organization 6.553934e-6
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade 7.459686e-6
GO:0009088 threonine biosynthetic process 7.494117e-6
GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade 7.586062e-6
GO:0003209 cardiac atrium morphogenesis 9.100340e-6
GO:0014850 response to muscle activity 9.212798e-6
GO:0006875 cellular metal ion homeostasis 9.339309e-6
GO:0034103 regulation of tissue remodeling 9.640400e-6
GO:0003230 cardiac atrium development 1.058016e-5
GO:0035964 COPI-coated vesicle budding 1.071223e-5
GO:0048513 organ development 1.276028e-5
GO:0030003 cellular cation homeostasis 1.325826e-5
GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis 1.327564e-5
GO:0009967 positive regulation of signal transduction 1.347378e-5
GO:0036006 cellular response to macrophage colony-stimulating factor stimulus 1.397955e-5
GO:0031017 exocrine pancreas development 1.502117e-5
GO:0019725 cellular homeostasis 1.503410e-5
GO:0006812 cation transport 1.518912e-5
GO:0007588 excretion 1.544007e-5
GO:0007258 JUN phosphorylation 1.621493e-5
GO:0006029 proteoglycan metabolic process 1.856508e-5
GO:0006954 inflammatory response 1.857363e-5
GO:0002407 dendritic cell chemotaxis 2.250672e-5
GO:0055082 cellular chemical homeostasis 2.339088e-5
GO:0046850 regulation of bone remodeling 2.350503e-5
GO:0014732 skeletal muscle atrophy 2.434792e-5
GO:0061307 cardiac neural crest cell differentiation involved in heart development 2.475122e-5
GO:0071731 response to nitric oxide 2.564505e-5
GO:0048193 Golgi vesicle transport 2.949583e-5
GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development 2.970197e-5
GO:0006955 immune response 3.002528e-5
GO:0044093 positive regulation of molecular function 3.082311e-5
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 3.120698e-5
GO:0015876 acetyl-CoA transport 3.166450e-5
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 3.324523e-5
GO:0045085 negative regulation of interleukin-2 biosynthetic process 3.421471e-5
GO:0048678 response to axon injury 3.462077e-5
GO:0009415 response to water 3.577882e-5
GO:0007186 G-protein coupled receptor protein signaling pathway 3.578094e-5
GO:0000045 autophagic vacuole assembly 3.772015e-5
GO:0032501 multicellular organismal process 4.261059e-5
GO:0010994 free ubiquitin chain polymerization 4.520408e-5
GO:0043270 positive regulation of ion transport 4.722290e-5
GO:0042036 negative regulation of cytokine biosynthetic process 4.950089e-5
GO:0006566 threonine metabolic process 5.206015e-5
GO:0060282 positive regulation of oocyte development 6.090698e-5
GO:0060281 regulation of oocyte development 6.090698e-5
GO:0045725 positive regulation of glycogen biosynthetic process 6.154400e-5
GO:0015755 fructose transport 6.246811e-5
GO:0007167 enzyme linked receptor protein signaling pathway 6.775092e-5
GO:0044057 regulation of system process 6.787550e-5
GO:0045821 positive regulation of glycolysis 6.924803e-5
GO:0001661 conditioned taste aversion 6.925102e-5
GO:0006914 autophagy 7.157817e-5
GO:0070663 regulation of leukocyte proliferation 7.664170e-5
GO:0010765 positive regulation of sodium ion transport 7.773632e-5
GO:0014904 myotube cell development 7.929119e-5
GO:0035909 aorta morphogenesis 7.996835e-5
GO:0042221 response to chemical stimulus 8.285543e-5
GO:0048856 anatomical structure development 8.613009e-5
GO:0065009 regulation of molecular function 8.823345e-5
GO:0050789 regulation of biological process 8.894571e-5
GO:0030001 metal ion transport 8.973302e-5
GO:0010633 negative regulation of epithelial cell migration 8.998462e-5
GO:0009743 response to carbohydrate stimulus 9.026841e-5
GO:0014911 positive regulation of smooth muscle cell migration 9.138536e-5
GO:0045937 positive regulation of phosphate metabolic process 9.521186e-5
GO:0042035 regulation of cytokine biosynthetic process 9.855498e-5
GO:0045190 isotype switching 1.013952e-4
GO:0042327 positive regulation of phosphorylation 1.041601e-4
GO:0006172 ADP biosynthetic process 1.067728e-4
GO:0015711 organic anion transport 1.139733e-4
GO:0090257 regulation of muscle system process 1.161112e-4
GO:0032944 regulation of mononuclear cell proliferation 1.174379e-4
GO:0009179 purine ribonucleoside diphosphate metabolic process 1.189961e-4
GO:0006873 cellular ion homeostasis 1.296328e-4
GO:0055074 calcium ion homeostasis 1.314116e-4
GO:0032789 unsaturated monocarboxylic acid metabolic process 1.322298e-4
GO:0032788 saturated monocarboxylic acid metabolic process 1.322298e-4
GO:0007275 multicellular organismal development 1.366926e-4
GO:0031960 response to corticosteroid stimulus 1.369195e-4
GO:2000249 regulation of actin cytoskeleton reorganization 1.403966e-4
GO:0060326 cell chemotaxis 1.404773e-4
GO:0045651 positive regulation of macrophage differentiation 1.426488e-4
GO:0010811 positive regulation of cell-substrate adhesion 1.457829e-4
GO:0045058 T cell selection 1.499890e-4
GO:0002312 B cell activation involved in immune response 1.531776e-4
GO:0043067 regulation of programmed cell death 1.539665e-4
GO:0042534 regulation of tumor necrosis factor biosynthetic process 1.555606e-4
GO:0032535 regulation of cellular component size 1.646131e-4
GO:0035590 purinergic nucleotide receptor signaling pathway 1.649255e-4
GO:0042594 response to starvation 1.736324e-4
GO:0050654 chondroitin sulfate proteoglycan metabolic process 1.743627e-4
GO:0009651 response to salt stress 1.753598e-4
GO:0007625 grooming behavior 1.779632e-4
GO:0031103 axon regeneration 1.906933e-4
GO:0032092 positive regulation of protein binding 1.930104e-4
GO:0042981 regulation of apoptosis 1.933271e-4
GO:0006952 defense response 1.945462e-4
GO:0003091 renal water homeostasis 1.974283e-4
GO:0031295 T cell costimulation 1.985252e-4
GO:0010960 magnesium ion homeostasis 1.987037e-4
GO:0055009 atrial cardiac muscle tissue morphogenesis 1.994786e-4
GO:0003278 apoptosis involved in heart morphogenesis 2.032169e-4
GO:2000353 positive regulation of endothelial cell apoptosis 2.039552e-4
GO:0009100 glycoprotein metabolic process 2.047899e-4
GO:0023056 positive regulation of signaling 2.075207e-4
GO:0031102 neuron projection regeneration 2.100886e-4
GO:0055005 ventricular cardiac myofibril development 2.103295e-4
GO:0050670 regulation of lymphocyte proliferation 2.154522e-4
GO:0030850 prostate gland development 2.155493e-4
GO:0045124 regulation of bone resorption 2.171545e-4
GO:0014889 muscle atrophy 2.254350e-4
GO:0009069 serine family amino acid metabolic process 2.304007e-4
GO:0010646 regulation of cell communication 2.398751e-4
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway 2.423882e-4
GO:0010647 positive regulation of cell communication 2.424541e-4
GO:0003347 epicardial cell to mesenchymal cell transition 2.450756e-4
GO:0031016 pancreas development 2.457736e-4
GO:0006937 regulation of muscle contraction 2.564160e-4
GO:0030168 platelet activation 2.687103e-4
GO:0045076 regulation of interleukin-2 biosynthetic process 2.697694e-4
GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade 2.704646e-4
GO:0034605 cellular response to heat 2.729038e-4
GO:0000238 zygotene 2.833740e-4
GO:0051247 positive regulation of protein metabolic process 2.980823e-4
GO:0055085 transmembrane transport 2.987037e-4
GO:0035587 purinergic receptor signaling pathway 3.093588e-4
GO:0010759 positive regulation of macrophage chemotaxis 3.191534e-4
GO:0042129 regulation of T cell proliferation 3.230276e-4
GO:0060413 atrial septum morphogenesis 3.245391e-4
GO:0060512 prostate gland morphogenesis 3.446125e-4
GO:0009414 response to water deprivation 3.845199e-4
GO:0002366 leukocyte activation involved in immune response 3.993125e-4
GO:0030099 myeloid cell differentiation 4.353669e-4
GO:2000271 positive regulation of fibroblast apoptosis 4.377983e-4
GO:2000270 negative regulation of fibroblast apoptosis 4.377983e-4
GO:2000080 negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 4.377983e-4
GO:0044345 stromal-epithelial cell signaling involved in prostate gland development 4.377983e-4
GO:0045062 extrathymic T cell selection 4.443918e-4
GO:0090186 regulation of pancreatic juice secretion 4.453696e-4
GO:0090182 regulation of secretion of lysosomal enzymes 4.453696e-4
GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation 4.453696e-4
GO:0048550 negative regulation of pinocytosis 4.453696e-4
GO:0030595 leukocyte chemotaxis 4.469096e-4
GO:0009134 nucleoside diphosphate catabolic process 4.511867e-4
GO:0048584 positive regulation of response to stimulus 4.588477e-4
GO:0010632 regulation of epithelial cell migration 4.598358e-4
GO:0070875 positive regulation of glycogen metabolic process 4.631733e-4
GO:0008284 positive regulation of cell proliferation 4.720442e-4
GO:0009628 response to abiotic stimulus 4.744819e-4
GO:2000522 positive regulation of immunological synapse formation 4.842084e-4
GO:0010033 response to organic substance 4.854748e-4
GO:0032270 positive regulation of cellular protein metabolic process 4.965894e-4
GO:0007213 muscarinic acetylcholine receptor signaling pathway 5.015981e-4
GO:0009071 serine family amino acid catabolic process 5.052909e-4
GO:0035588 G-protein coupled purinergic receptor signaling pathway 5.101713e-4
GO:0006487 protein N-linked glycosylation 5.129209e-4
GO:0051179 localization 5.160272e-4
GO:0050852 T cell receptor signaling pathway 5.268349e-4
GO:0003283 atrial septum development 5.415400e-4
GO:0048096 chromatin-mediated maintenance of transcription 5.439931e-4
GO:0050851 antigen receptor-mediated signaling pathway 5.600510e-4
GO:0071305 cellular response to vitamin D 5.677899e-4
GO:2000833 positive regulation of steroid hormone secretion 5.868845e-4
GO:0070647 protein modification by small protein conjugation or removal 5.957915e-4
GO:0070228 regulation of lymphocyte apoptosis 5.972211e-4
GO:0010951 negative regulation of endopeptidase activity 6.195391e-4
GO:0006704 glucocorticoid biosynthetic process 6.324369e-4
GO:0008206 bile acid metabolic process 6.494617e-4
GO:0006816 calcium ion transport 6.761471e-4
GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 6.820007e-4
GO:0002604 regulation of dendritic cell antigen processing and presentation 6.820007e-4
GO:0034341 response to interferon-gamma 6.900240e-4
GO:0060736 prostate gland growth 6.955386e-4
GO:0018149 peptide cross-linking 7.134714e-4
GO:0002028 regulation of sodium ion transport 7.134714e-4
GO:0070234 positive regulation of T cell apoptosis 7.337123e-4
GO:0003289 atrial septum primum morphogenesis 7.529237e-4
GO:0048548 regulation of pinocytosis 7.670600e-4
GO:0021558 trochlear nerve development 7.670600e-4
GO:0043089 positive regulation of Cdc42 GTPase activity 7.721048e-4
GO:0009966 regulation of signal transduction 7.833521e-4
GO:0016236 macroautophagy 8.013472e-4
GO:0060740 prostate gland epithelium morphogenesis 8.158217e-4
GO:0003012 muscle system process 8.181048e-4
GO:0043248 proteasome assembly 8.264967e-4
GO:0046631 alpha-beta T cell activation 8.580046e-4
GO:2000079 regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 8.594403e-4
GO:0071380 cellular response to prostaglandin E stimulus 8.594403e-4
GO:0030521 androgen receptor signaling pathway 8.863159e-4
GO:0000245 spliceosome assembly 8.863159e-4
GO:0030890 positive regulation of B cell proliferation 9.033710e-4
GO:0072507 divalent inorganic cation homeostasis 9.068907e-4
GO:0045082 positive regulation of interleukin-10 biosynthetic process 9.122167e-4
GO:0009191 ribonucleoside diphosphate catabolic process 9.141843e-4
GO:0035335 peptidyl-tyrosine dephosphorylation 9.210083e-4
GO:0031399 regulation of protein modification process 9.326346e-4
GO:0050870 positive regulation of T cell activation 9.398792e-4
GO:0010766 negative regulation of sodium ion transport 9.629621e-4
GO:0051480 cytosolic calcium ion homeostasis 9.652835e-4
GO:0010941 regulation of cell death 9.672788e-4
GO:0042438 melanin biosynthetic process 9.901001e-4
GO:0009267 cellular response to starvation 1.008823e-3
GO:0035630 bone mineralization involved in bone maturation 1.010176e-3
GO:0034695 response to prostaglandin E stimulus 1.020090e-3
GO:0046626 regulation of insulin receptor signaling pathway 1.020793e-3
GO:0060412 ventricular septum morphogenesis 1.032182e-3
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein 1.058001e-3
GO:0023051 regulation of signaling 1.064631e-3
GO:0003009 skeletal muscle contraction 1.070136e-3
GO:0009749 response to glucose stimulus 1.071452e-3
GO:0048250 mitochondrial iron ion transport 1.122511e-3
GO:0009437 carnitine metabolic process 1.150084e-3
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 1.155738e-3
GO:0051182 coenzyme transport 1.160286e-3
GO:0051639 actin filament network formation 1.165832e-3
GO:0010232 vascular transport 1.165832e-3
GO:0051541 elastin metabolic process 1.204241e-3
GO:0043088 regulation of Cdc42 GTPase activity 1.212439e-3
GO:0003281 ventricular septum development 1.234060e-3
GO:0009719 response to endogenous stimulus 1.252720e-3
GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway 1.301270e-3
GO:0007031 peroxisome organization 1.302978e-3
GO:0070972 protein localization in endoplasmic reticulum 1.308306e-3
GO:0032271 regulation of protein polymerization 1.316983e-3
GO:0042325 regulation of phosphorylation 1.352407e-3
GO:0006750 glutathione biosynthetic process 1.358935e-3
GO:0010970 microtubule-based transport 1.407246e-3
GO:0030913 paranodal junction assembly 1.420752e-3
GO:0051915 induction of synaptic plasticity by chemical substance 1.437111e-3
GO:0031018 endocrine pancreas development 1.453427e-3
GO:0070977 bone maturation 1.479554e-3
GO:0001833 inner cell mass cell proliferation 1.489243e-3
GO:0045103 intermediate filament-based process 1.496618e-3
GO:0043065 positive regulation of apoptosis 1.502496e-3
GO:0048545 response to steroid hormone stimulus 1.502938e-3
GO:0030166 proteoglycan biosynthetic process 1.503018e-3
GO:0033574 response to testosterone stimulus 1.554795e-3
GO:0032846 positive regulation of homeostatic process 1.555019e-3
GO:0006582 melanin metabolic process 1.557290e-3
GO:0071460 cellular response to cell-matrix adhesion 1.564020e-3
GO:0045345 positive regulation of MHC class I biosynthetic process 1.564020e-3
GO:0045409 negative regulation of interleukin-6 biosynthetic process 1.584833e-3
GO:0034284 response to monosaccharide stimulus 1.621136e-3
GO:0010758 regulation of macrophage chemotaxis 1.621947e-3
GO:0050865 regulation of cell activation 1.629570e-3
GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis 1.630005e-3
GO:0061325 cell proliferation involved in outflow tract morphogenesis 1.630005e-3
GO:0070245 positive regulation of thymocyte apoptosis 1.634368e-3
GO:0006621 protein retention in ER lumen 1.636620e-3
GO:0009314 response to radiation 1.676522e-3
GO:0031401 positive regulation of protein modification process 1.681321e-3
GO:0006790 sulfur compound metabolic process 1.688519e-3
GO:0002694 regulation of leukocyte activation 1.695528e-3
GO:0010907 positive regulation of glucose metabolic process 1.713976e-3
GO:0071474 cellular hyperosmotic response 1.723904e-3
GO:0046487 glyoxylate metabolic process 1.723904e-3
GO:0048679 regulation of axon regeneration 1.734617e-3
GO:0046651 lymphocyte proliferation 1.758968e-3
GO:0051409 response to nitrosative stress 1.765142e-3
GO:0072355 histone H3-T3 phosphorylation 1.779708e-3
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 1.784058e-3
GO:0050867 positive regulation of cell activation 1.791393e-3
GO:0006376 mRNA splice site selection 1.794630e-3
GO:0048813 dendrite morphogenesis 1.796819e-3
GO:2000978 negative regulation of forebrain neuron differentiation 1.811160e-3
GO:2000227 negative regulation of pancreatic A cell differentiation 1.811160e-3
GO:0046331 lateral inhibition 1.811160e-3
GO:0061106 negative regulation of stomach neuroendocrine cell differentiation 1.811160e-3
GO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation 1.833337e-3
GO:0035910 ascending aorta morphogenesis 1.833337e-3
GO:0010038 response to metal ion 1.895951e-3
GO:0006536 glutamate metabolic process 1.905322e-3
GO:0071675 regulation of mononuclear cell migration 1.908150e-3
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 1.912045e-3
GO:0045074 regulation of interleukin-10 biosynthetic process 1.942379e-3
GO:0010739 positive regulation of protein kinase A signaling cascade 1.962374e-3
GO:2000831 regulation of steroid hormone secretion 1.962374e-3
GO:0019220 regulation of phosphate metabolic process 1.977314e-3
GO:0006548 histidine catabolic process 2.056231e-3
GO:0043068 positive regulation of programmed cell death 2.110301e-3
GO:0043043 peptide biosynthetic process 2.121309e-3
GO:0060741 prostate gland stromal morphogenesis 2.126798e-3
GO:0071622 regulation of granulocyte chemotaxis 2.155550e-3
GO:0002903 negative regulation of B cell apoptosis 2.155550e-3
GO:0010035 response to inorganic substance 2.156098e-3
GO:0005978 glycogen biosynthetic process 2.162578e-3
GO:0031113 regulation of microtubule polymerization 2.170155e-3
GO:0005979 regulation of glycogen biosynthetic process 2.174714e-3
GO:0043252 sodium-independent organic anion transport 2.196452e-3
GO:0034725 DNA replication-dependent nucleosome disassembly 2.196452e-3
GO:0030299 intestinal cholesterol absorption 2.284270e-3
GO:0042098 T cell proliferation 2.304048e-3
GO:0050790 regulation of catalytic activity 2.346836e-3
GO:0045348 positive regulation of MHC class II biosynthetic process 2.348757e-3
GO:0002246 wound healing involved in inflammatory response 2.352455e-3
GO:0035019 somatic stem cell maintenance 2.395787e-3
GO:0009629 response to gravity 2.432798e-3
GO:0070230 positive regulation of lymphocyte apoptosis 2.434581e-3
GO:0007204 elevation of cytosolic calcium ion concentration 2.494803e-3
GO:0048638 regulation of developmental growth 2.515311e-3
GO:0031650 regulation of heat generation 2.535230e-3
GO:0010942 positive regulation of cell death 2.566612e-3
GO:0001866 NK T cell proliferation 2.572179e-3
GO:0071842 cellular component organization at cellular level 2.601214e-3
GO:0034214 protein hexamerization 2.607831e-3
GO:0045061 thymic T cell selection 2.639396e-3
GO:0002429 immune response-activating cell surface receptor signaling pathway 2.654799e-3
GO:0048199 vesicle targeting, to, from or within Golgi 2.656143e-3
GO:0002906 negative regulation of mature B cell apoptosis 2.670438e-3
GO:0010501 RNA secondary structure unwinding 2.672141e-3
GO:0007181 transforming growth factor beta receptor complex assembly 2.672141e-3
GO:0010466 negative regulation of peptidase activity 2.694128e-3
GO:0010719 negative regulation of epithelial to mesenchymal transition 2.698182e-3
GO:0046579 positive regulation of Ras protein signal transduction 2.701719e-3
GO:0009607 response to biotic stimulus 2.706512e-3
GO:0007596 blood coagulation 2.721987e-3
GO:0009746 response to hexose stimulus 2.724023e-3
GO:0042536 negative regulation of tumor necrosis factor biosynthetic process 2.724610e-3
GO:0051246 regulation of protein metabolic process 2.751128e-3
GO:0009992 cellular water homeostasis 2.785898e-3
GO:0042747 circadian sleep/wake cycle, REM sleep 2.785898e-3
GO:0072321 chaperone-mediated protein transport 2.792416e-3
GO:0051707 response to other organism 2.837046e-3
GO:0050877 neurological system process 2.885150e-3
GO:0045780 positive regulation of bone resorption 2.907102e-3
GO:0045064 T-helper 2 cell differentiation 2.946926e-3
GO:0045988 negative regulation of striated muscle contraction 2.962090e-3
GO:0060411 cardiac septum morphogenesis 2.975570e-3
GO:0007599 hemostasis 2.992567e-3
GO:2000107 negative regulation of leukocyte apoptosis 3.003926e-3
GO:0032844 regulation of homeostatic process 3.104400e-3
GO:0009725 response to hormone stimulus 3.165997e-3
GO:0040012 regulation of locomotion 3.167864e-3
GO:0033085 negative regulation of T cell differentiation in thymus 3.179075e-3
GO:0010724 regulation of definitive erythrocyte differentiation 3.189359e-3
GO:0071496 cellular response to external stimulus 3.190836e-3
GO:0071402 cellular response to lipoprotein particle stimulus 3.204234e-3
GO:0043269 regulation of ion transport 3.242497e-3
GO:0010959 regulation of metal ion transport 3.271405e-3
GO:0050794 regulation of cellular process 3.294215e-3
GO:0043383 negative T cell selection 3.352038e-3
GO:0034392 negative regulation of smooth muscle cell apoptosis 3.361525e-3
GO:0010676 positive regulation of cellular carbohydrate metabolic process 3.367512e-3
GO:0045671 negative regulation of osteoclast differentiation 3.398051e-3
GO:0043085 positive regulation of catalytic activity 3.398895e-3
GO:0072595 maintenance of protein localization to organelle 3.402675e-3
GO:0051081 nuclear envelope disassembly 3.464640e-3
GO:0015911 plasma membrane long-chain fatty acid transport 3.464640e-3
GO:0009201 ribonucleoside triphosphate biosynthetic process 3.472505e-3
GO:0001934 positive regulation of protein phosphorylation 3.493126e-3
GO:0006874 cellular calcium ion homeostasis 3.534698e-3
GO:0003206 cardiac chamber morphogenesis 3.588551e-3
GO:0046627 negative regulation of insulin receptor signaling pathway 3.592101e-3
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 3.693635e-3
GO:0000147 actin cortical patch assembly 3.726269e-3
GO:0071392 cellular response to estradiol stimulus 3.735051e-3
GO:0048505 regulation of timing of cell differentiation 3.762722e-3
GO:0048676 axon extension involved in development 3.762722e-3
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 3.816170e-3
GO:0019827 stem cell maintenance 3.831137e-3
GO:0002285 lymphocyte activation involved in immune response 3.834970e-3
GO:0030432 peristalsis 3.913597e-3
GO:0001819 positive regulation of cytokine production 3.918984e-3
GO:0060973 cell migration involved in heart development 3.944518e-3
GO:0052548 regulation of endopeptidase activity 3.945807e-3
GO:0032943 mononuclear cell proliferation 4.021237e-3
GO:0001501 skeletal system development 4.051486e-3
GO:0032663 regulation of interleukin-2 production 4.152229e-3
GO:0070914 UV-damage excision repair 4.157456e-3
GO:0008582 regulation of synaptic growth at neuromuscular junction 4.157456e-3
GO:0010224 response to UV-B 4.176379e-3
GO:0000041 transition metal ion transport 4.236183e-3
GO:0006547 histidine metabolic process 4.239105e-3
GO:0070661 leukocyte proliferation 4.240050e-3
GO:0032878 regulation of establishment or maintenance of cell polarity 4.243786e-3
GO:0046034 ATP metabolic process 4.260682e-3
GO:0009416 response to light stimulus 4.260682e-3
GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration 4.275020e-3
GO:0048305 immunoglobulin secretion 4.280136e-3
GO:0046341 CDP-diacylglycerol metabolic process 4.316953e-3
GO:0097026 dendritic cell dendrite assembly 4.316953e-3
GO:0032633 interleukin-4 production 4.316953e-3
GO:0038003 opioid receptor signaling pathway 4.316953e-3
GO:0001865 NK T cell differentiation 4.316953e-3
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 4.318997e-3
GO:0006168 adenine salvage 4.327781e-3
GO:0048840 otolith development 4.348339e-3
GO:0055119 relaxation of cardiac muscle 4.348339e-3
GO:0001932 regulation of protein phosphorylation 4.352891e-3
GO:0048478 replication fork protection 4.370708e-3
GO:0034755 iron ion transmembrane transport 4.479207e-3
GO:0002757 immune response-activating signal transduction 4.507260e-3
GO:0070307 lens fiber cell development 4.546205e-3
GO:0002577 regulation of antigen processing and presentation 4.588562e-3
GO:0019748 secondary metabolic process 4.633392e-3
GO:0032496 response to lipopolysaccharide 4.655492e-3
GO:0006544 glycine metabolic process 4.661963e-3
GO:0050862 positive regulation of T cell receptor signaling pathway 4.687389e-3
GO:0007342 fusion of sperm to egg plasma membrane 4.687389e-3
GO:0046632 alpha-beta T cell differentiation 4.693468e-3
GO:0001832 blastocyst growth 4.746645e-3
GO:0060088 auditory receptor cell stereocilium organization 4.752500e-3
GO:0051181 cofactor transport 4.752500e-3
GO:0007033 vacuole organization 4.761450e-3
GO:0003231 cardiac ventricle development 4.776331e-3
GO:0045815 positive regulation of gene expression, epigenetic 4.863127e-3
GO:0030212 hyaluronan metabolic process 4.863127e-3
GO:0050863 regulation of T cell activation 4.884063e-3
GO:0006754 ATP biosynthetic process 4.989459e-3
GO:0046628 positive regulation of insulin receptor signaling pathway 5.016262e-3
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 5.051909e-3
GO:0048771 tissue remodeling 5.096870e-3
GO:0047497 mitochondrion transport along microtubule 5.135092e-3
GO:0003407 neural retina development 5.137078e-3
GO:0007015 actin filament organization 5.144909e-3
GO:0006953 acute-phase response 5.177453e-3
GO:0048015 phosphatidylinositol-mediated signaling 5.177453e-3
GO:0090066 regulation of anatomical structure size 5.221694e-3
GO:0001743 optic placode formation 5.224828e-3
GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase 5.233589e-3
GO:0014066 regulation of phosphatidylinositol 3-kinase cascade 5.292020e-3
GO:0043403 skeletal muscle tissue regeneration 5.292841e-3
GO:0071732 cellular response to nitric oxide 5.300249e-3
GO:0002328 pro-B cell differentiation 5.300249e-3
GO:0045123 cellular extravasation 5.343590e-3
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 5.424081e-3
GO:0002369 T cell cytokine production 5.424081e-3
GO:0060013 righting reflex 5.426375e-3
GO:0060401 cytosolic calcium ion transport 5.475399e-3
GO:2000106 regulation of leukocyte apoptosis 5.489107e-3