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Novel motif:99

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name:motif99_GYGTSANACG

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0019101 female somatic sex determination 5.852615e-10
GO:0042703 menstruation 5.852615e-10
GO:0048075 positive regulation of eye pigmentation 1.417686e-9
GO:0048820 hair follicle maturation 1.776615e-9
GO:0097045 phosphatidylserine exposure on blood platelet 2.934390e-9
GO:0002074 extraocular skeletal muscle development 3.828453e-9
GO:0046602 regulation of mitotic centrosome separation 6.589448e-9
GO:0016577 histone demethylation 9.409624e-9
GO:0046604 positive regulation of mitotic centrosome separation 1.009981e-8
GO:0016197 endosome transport 1.103854e-8
GO:0051898 negative regulation of protein kinase B signaling cascade 1.242746e-8
GO:0090232 positive regulation of spindle checkpoint 1.300326e-8
GO:0048024 regulation of nuclear mRNA splicing, via spliceosome 1.683242e-8
GO:0046607 positive regulation of centrosome cycle 2.376271e-8
GO:0048073 regulation of eye pigmentation 2.827556e-8
GO:0090234 regulation of kinetochore assembly 2.828154e-8
GO:0090169 regulation of spindle assembly 2.828154e-8
GO:0006482 protein demethylation 3.064968e-8
GO:0060384 innervation 5.089808e-8
GO:0060134 prepulse inhibition 6.470599e-8
GO:0070988 demethylation 7.491659e-8
GO:0090304 nucleic acid metabolic process 1.499656e-7
GO:0030237 female sex determination 2.696113e-7
GO:0043484 regulation of RNA splicing 2.869084e-7
GO:0000381 regulation of alternative nuclear mRNA splicing, via spliceosome 3.123562e-7
GO:0090224 regulation of spindle organization 3.133419e-7
GO:0000375 RNA splicing, via transesterification reactions 3.359403e-7
GO:0008333 endosome to lysosome transport 3.822477e-7
GO:0060014 granulosa cell differentiation 3.962618e-7
GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response 4.040543e-7
GO:0090141 positive regulation of mitochondrial fission 4.285524e-7
GO:0000398 nuclear mRNA splicing, via spliceosome 4.329663e-7
GO:0006730 one-carbon metabolic process 7.855999e-7
GO:0042640 anagen 8.968854e-7
GO:0090231 regulation of spindle checkpoint 9.638487e-7
GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development 1.049972e-6
GO:0003061 positive regulation of the force of heart contraction by norepinephrine 1.049972e-6
GO:0018993 somatic sex determination 1.054354e-6
GO:0016070 RNA metabolic process 1.466817e-6
GO:0060216 definitive hemopoiesis 1.538289e-6
GO:0006844 acyl carnitine transport 1.584923e-6
GO:0007041 lysosomal transport 1.780729e-6
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 1.837745e-6
GO:0051438 regulation of ubiquitin-protein ligase activity 1.970677e-6
GO:0018283 iron incorporation into metallo-sulfur cluster 2.031805e-6
GO:0072333 signal transduction by p53 class mediator resulting in induction of anoikis 2.077460e-6
GO:0050684 regulation of mRNA processing 2.451097e-6
GO:0016032 viral reproduction 2.478223e-6
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 2.567816e-6
GO:0051443 positive regulation of ubiquitin-protein ligase activity 2.750289e-6
GO:0070345 negative regulation of fat cell proliferation 3.115310e-6
GO:0034776 response to histamine 3.708242e-6
GO:0000413 protein peptidyl-prolyl isomerization 4.408054e-6
GO:0070831 basement membrane assembly 4.498197e-6
GO:0090230 regulation of centromere complex assembly 4.817360e-6
GO:0071843 cellular component biogenesis at cellular level 5.853729e-6
GO:0090140 regulation of mitochondrial fission 5.948182e-6
GO:0034371 chylomicron remodeling 6.574951e-6
GO:0022038 corpus callosum development 7.611534e-6
GO:0022618 ribonucleoprotein complex assembly 7.700052e-6
GO:0022613 ribonucleoprotein complex biogenesis 8.213512e-6
GO:0045022 early endosome to late endosome transport 1.007438e-5
GO:0007034 vacuolar transport 1.028083e-5
GO:2000210 positive regulation of anoikis 1.042925e-5
GO:0010467 gene expression 1.271337e-5
GO:0006837 serotonin transport 1.312354e-5
GO:0044260 cellular macromolecule metabolic process 1.417533e-5
GO:0055025 positive regulation of cardiac muscle tissue development 1.539225e-5
GO:0050746 regulation of lipoprotein metabolic process 1.579532e-5
GO:0060691 epithelial cell maturation involved in salivary gland development 1.633338e-5
GO:0060096 serotonin secretion, neurotransmission 1.633338e-5
GO:0021506 anterior neuropore closure 1.714888e-5
GO:0007181 transforming growth factor beta receptor complex assembly 1.723916e-5
GO:0001510 RNA methylation 1.793204e-5
GO:0006139 nucleobase-containing compound metabolic process 1.865402e-5
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 1.889528e-5
GO:0043353 enucleate erythrocyte differentiation 1.959057e-5
GO:0042167 heme catabolic process 2.017994e-5
GO:0000724 double-strand break repair via homologous recombination 2.387141e-5
GO:0050747 positive regulation of lipoprotein metabolic process 2.405610e-5
GO:2000096 positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway 2.517957e-5
GO:0007214 gamma-aminobutyric acid signaling pathway 2.648185e-5
GO:0050652 dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 2.744617e-5
GO:0071826 ribonucleoprotein complex subunit organization 2.882687e-5
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 3.040769e-5
GO:0000725 recombinational repair 3.181018e-5
GO:0035854 eosinophil fate commitment 3.257386e-5
GO:0030222 eosinophil differentiation 3.257386e-5
GO:0071156 regulation of cell cycle arrest 3.309672e-5
GO:0034621 cellular macromolecular complex subunit organization 3.329457e-5
GO:0006907 pinocytosis 3.429940e-5
GO:0018208 peptidyl-proline modification 3.590734e-5
GO:0006457 protein folding 3.896030e-5
GO:0030262 apoptotic nuclear change 4.087831e-5
GO:0008053 mitochondrial fusion 4.106534e-5
GO:0014807 regulation of somitogenesis 4.246284e-5
GO:2000065 negative regulation of cortisol biosynthetic process 4.329072e-5
GO:0032348 negative regulation of aldosterone biosynthetic process 4.329072e-5
GO:2000095 regulation of Wnt receptor signaling pathway, planar cell polarity pathway 4.484674e-5
GO:0050883 musculoskeletal movement, spinal reflex action 4.774587e-5
GO:0007386 compartment pattern specification 5.148322e-5
GO:0016926 protein desumoylation 5.378235e-5
GO:0034622 cellular macromolecular complex assembly 5.381246e-5
GO:2000466 negative regulation of glycogen (starch) synthase activity 5.485833e-5
GO:0051340 regulation of ligase activity 5.517570e-5
GO:0048048 embryonic eye morphogenesis 6.379064e-5
GO:0010002 cardioblast differentiation 6.405599e-5
GO:0007021 tubulin complex assembly 6.602235e-5
GO:0035461 vitamin transmembrane transport 6.716370e-5
GO:0051705 behavioral interaction between organisms 7.195799e-5
GO:0071279 cellular response to cobalt ion 7.365742e-5
GO:0010637 negative regulation of mitochondrial fusion 7.365742e-5
GO:0000073 spindle pole body separation 7.365742e-5
GO:0050775 positive regulation of dendrite morphogenesis 7.409453e-5
GO:0051684 maintenance of Golgi location 7.539729e-5
GO:2000178 negative regulation of neural precursor cell proliferation 8.470054e-5
GO:0071695 anatomical structure maturation 9.197326e-5
GO:0007212 dopamine receptor signaling pathway 9.354431e-5
GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway 1.014768e-4
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.037440e-4
GO:0051444 negative regulation of ubiquitin-protein ligase activity 1.073499e-4
GO:0051351 positive regulation of ligase activity 1.106505e-4
GO:0042637 catagen 1.125740e-4
GO:0060763 mammary duct terminal end bud growth 1.158572e-4
GO:0090002 establishment of protein localization in plasma membrane 1.162578e-4
GO:0000209 protein polyubiquitination 1.181802e-4
GO:0034063 stress granule assembly 1.187647e-4
GO:0072668 tubulin complex biogenesis 1.197532e-4
GO:0043004 cytoplasmic sequestering of CFTR protein 1.219880e-4
GO:0042596 fear response 1.242681e-4
GO:0003264 regulation of cardioblast proliferation 1.324640e-4
GO:0010890 positive regulation of sequestering of triglyceride 1.357571e-4
GO:0010742 macrophage derived foam cell differentiation 1.500587e-4
GO:0000216 M/G1 transition of mitotic cell cycle 1.509442e-4
GO:0021623 oculomotor nerve formation 1.566380e-4
GO:0003409 optic cup structural organization 1.566380e-4
GO:0003404 optic vesicle morphogenesis 1.566380e-4
GO:0070076 histone lysine demethylation 1.623918e-4
GO:0046390 ribose phosphate biosynthetic process 1.629077e-4
GO:0051452 intracellular pH reduction 1.767766e-4
GO:0010741 negative regulation of intracellular protein kinase cascade 1.846128e-4
GO:0031104 dendrite regeneration 1.882564e-4
GO:0071934 thiamine transmembrane transport 1.924244e-4
GO:2000209 regulation of anoikis 1.992450e-4
GO:0070172 positive regulation of tooth mineralization 1.992450e-4
GO:0001964 startle response 2.094444e-4
GO:0061050 regulation of cell growth involved in cardiac muscle cell development 2.106623e-4
GO:0009446 putrescine biosynthetic process 2.147962e-4
GO:0048087 positive regulation of developmental pigmentation 2.216818e-4
GO:0002115 store-operated calcium entry 2.266249e-4
GO:0007221 positive regulation of transcription of Notch receptor target 2.266663e-4
GO:0045851 pH reduction 2.295589e-4
GO:0035967 cellular response to topologically incorrect protein 2.325165e-4
GO:0051181 cofactor transport 2.362444e-4
GO:0030968 endoplasmic reticulum unfolded protein response 2.378245e-4
GO:0032792 negative regulation of CREB transcription factor activity 2.388542e-4
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 2.439669e-4
GO:0050882 voluntary musculoskeletal movement 2.456992e-4
GO:0060160 negative regulation of dopamine receptor signaling pathway 2.490033e-4
GO:0090104 pancreatic E cell differentiation 2.516041e-4
GO:0003311 pancreatic D cell differentiation 2.516041e-4
GO:0072331 signal transduction by p53 class mediator 2.529372e-4
GO:0045955 negative regulation of calcium ion-dependent exocytosis 2.533598e-4
GO:2000052 positive regulation of non-canonical Wnt receptor signaling pathway 2.572986e-4
GO:0032203 telomere formation via telomerase 2.634208e-4
GO:0045719 negative regulation of glycogen biosynthetic process 2.639210e-4
GO:0034453 microtubule anchoring 2.705120e-4
GO:0007051 spindle organization 2.787901e-4
GO:0010944 negative regulation of transcription by competitive promoter binding 2.884409e-4
GO:0002551 mast cell chemotaxis 2.914114e-4
GO:0006739 NADP metabolic process 2.921942e-4
GO:2000097 regulation of smooth muscle cell-matrix adhesion 2.952815e-4
GO:0070344 regulation of fat cell proliferation 3.034124e-4
GO:0032874 positive regulation of stress-activated MAPK cascade 3.070277e-4
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 3.227385e-4
GO:2000050 regulation of non-canonical Wnt receptor signaling pathway 3.227665e-4
GO:0046755 non-lytic virus budding 3.248882e-4
GO:0006974 response to DNA damage stimulus 3.250237e-4
GO:0001662 behavioral fear response 3.301630e-4
GO:0002543 activation of blood coagulation via clotting cascade 3.403505e-4
GO:0001820 serotonin secretion 3.429750e-4
GO:0000077 DNA damage checkpoint 3.482750e-4
GO:0034976 response to endoplasmic reticulum stress 3.538678e-4
GO:0043414 macromolecule methylation 3.652196e-4
GO:0022601 menstrual cycle phase 3.793253e-4
GO:0034080 CenH3-containing nucleosome assembly at centromere 3.878902e-4
GO:0006479 protein methylation 3.925127e-4
GO:0071281 cellular response to iron ion 3.970667e-4
GO:0090150 establishment of protein localization in membrane 4.029245e-4
GO:0021819 layer formation in cerebral cortex 4.051610e-4
GO:0010878 cholesterol storage 4.263060e-4
GO:0048002 antigen processing and presentation of peptide antigen 4.311045e-4
GO:0002209 behavioral defense response 4.371546e-4
GO:0051647 nucleus localization 4.405731e-4
GO:0035811 negative regulation of urine volume 4.430437e-4
GO:0051453 regulation of intracellular pH 4.616924e-4
GO:0032223 negative regulation of synaptic transmission, cholinergic 4.759974e-4
GO:0045212 neurotransmitter receptor biosynthetic process 4.759974e-4
GO:0021933 radial glia guided migration of cerebellar granule cell 4.759974e-4
GO:0010734 negative regulation of protein glutathionylation 4.759974e-4
GO:0006781 succinyl-CoA pathway 4.759974e-4
GO:0070141 response to UV-A 4.835838e-4
GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure 4.980660e-4
GO:0070544 histone H3-K36 demethylation 5.125155e-4
GO:0010452 histone H3-K36 methylation 5.195983e-4
GO:0001302 replicative cell aging 5.272351e-4
GO:0070286 axonemal dynein complex assembly 5.301778e-4
GO:0031570 DNA integrity checkpoint 5.319192e-4
GO:0035621 ER to Golgi ceramide transport 5.449065e-4
GO:0046587 positive regulation of calcium-dependent cell-cell adhesion 5.449065e-4
GO:0033577 protein glycosylation in endoplasmic reticulum 5.449065e-4
GO:0002554 serotonin secretion by platelet 5.449065e-4
GO:0032774 RNA biosynthetic process 5.491684e-4
GO:0006984 ER-nucleus signaling pathway 5.769336e-4
GO:0017145 stem cell division 5.890990e-4
GO:0051973 positive regulation of telomerase activity 5.901935e-4
GO:0043461 proton-transporting ATP synthase complex assembly 5.932262e-4
GO:0009451 RNA modification 5.971489e-4
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 5.973635e-4
GO:0010889 regulation of sequestering of triglyceride 6.145316e-4
GO:0002089 lens morphogenesis in camera-type eye 6.341420e-4
GO:0045653 negative regulation of megakaryocyte differentiation 6.929460e-4
GO:0030421 defecation 6.963933e-4
GO:0050881 musculoskeletal movement 7.060302e-4
GO:0000075 cell cycle checkpoint 7.128033e-4
GO:0006414 translational elongation 7.151241e-4
GO:0006777 Mo-molybdopterin cofactor biosynthetic process 7.373002e-4
GO:0045652 regulation of megakaryocyte differentiation 7.394340e-4
GO:0048199 vesicle targeting, to, from or within Golgi 7.667746e-4
GO:0006281 DNA repair 8.301672e-4
GO:0051660 establishment of centrosome localization 8.376039e-4
GO:0021540 corpus callosum morphogenesis 8.376039e-4
GO:0006054 N-acetylneuraminate metabolic process 8.376039e-4
GO:0060690 epithelial cell differentiation involved in salivary gland development 8.379377e-4
GO:0031627 telomeric loop formation 8.394371e-4
GO:0006741 NADP biosynthetic process 8.394371e-4
GO:0044258 intestinal lipid catabolic process 8.443997e-4
GO:0018350 protein esterification 8.443997e-4
GO:0051148 negative regulation of muscle cell differentiation 8.638500e-4
GO:0006302 double-strand break repair 8.781848e-4
GO:0030953 astral microtubule organization 8.972909e-4
GO:0048203 vesicle targeting, trans-Golgi to endosome 9.012963e-4
GO:0051610 serotonin uptake 9.012963e-4
GO:0071423 malate transmembrane transport 9.042489e-4
GO:0072428 signal transduction involved in intra-S DNA damage checkpoint 9.042489e-4
GO:0015709 thiosulfate transport 9.042489e-4
GO:2000064 regulation of cortisol biosynthetic process 9.047488e-4
GO:0016071 mRNA metabolic process 9.250906e-4
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 9.405218e-4
GO:0001579 medium-chain fatty acid transport 9.587726e-4
GO:0045662 negative regulation of myoblast differentiation 9.706045e-4
GO:0048813 dendrite morphogenesis 1.017642e-3
GO:0034435 cholesterol esterification 1.035582e-3
GO:0032259 methylation 1.046186e-3
GO:0006188 IMP biosynthetic process 1.051499e-3
GO:0033169 histone H3-K9 demethylation 1.107877e-3
GO:0042481 regulation of odontogenesis 1.115238e-3
GO:0032922 circadian regulation of gene expression 1.119221e-3
GO:0006438 valyl-tRNA aminoacylation 1.132918e-3
GO:0007005 mitochondrion organization 1.150633e-3
GO:0033092 positive regulation of immature T cell proliferation in thymus 1.151809e-3
GO:0048148 behavioral response to cocaine 1.211884e-3
GO:0016081 synaptic vesicle docking involved in exocytosis 1.217136e-3
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.222917e-3
GO:0010868 negative regulation of triglyceride biosynthetic process 1.237980e-3
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 1.268762e-3
GO:0032981 mitochondrial respiratory chain complex I assembly 1.310310e-3
GO:0000245 spliceosome assembly 1.323437e-3
GO:0031397 negative regulation of protein ubiquitination 1.354788e-3
GO:0006924 activation-induced cell death of T cells 1.395842e-3
GO:0030641 regulation of cellular pH 1.398025e-3
GO:0051177 meiotic sister chromatid cohesion 1.451479e-3
GO:0003219 cardiac right ventricle formation 1.463824e-3
GO:0006509 membrane protein ectodomain proteolysis 1.482669e-3
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.488804e-3
GO:0046958 nonassociative learning 1.501820e-3
GO:0002635 negative regulation of germinal center formation 1.501820e-3
GO:0022027 interkinetic nuclear migration 1.543453e-3
GO:0031398 positive regulation of protein ubiquitination 1.548848e-3
GO:0035572 N-terminal peptidyl-serine dimethylation 1.551206e-3
GO:0035573 N-terminal peptidyl-serine trimethylation 1.551206e-3
GO:0018016 N-terminal peptidyl-proline dimethylation 1.551206e-3
GO:0018012 N-terminal peptidyl-alanine trimethylation 1.551206e-3
GO:0006308 DNA catabolic process 1.569674e-3
GO:0046907 intracellular transport 1.582942e-3
GO:0007588 excretion 1.618974e-3
GO:0001505 regulation of neurotransmitter levels 1.622903e-3
GO:0015844 monoamine transport 1.636812e-3
GO:0003334 keratinocyte development 1.639744e-3
GO:0006839 mitochondrial transport 1.649941e-3
GO:0032202 telomere assembly 1.659864e-3
GO:0006376 mRNA splice site selection 1.675036e-3
GO:0035305 negative regulation of dephosphorylation 1.732732e-3
GO:0070086 ubiquitin-dependent endocytosis 1.760818e-3
GO:0031125 rRNA 3'-end processing 1.761177e-3
GO:0006014 D-ribose metabolic process 1.896569e-3
GO:0048873 homeostasis of number of cells within a tissue 1.901214e-3
GO:0048692 negative regulation of axon extension involved in regeneration 1.955447e-3
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 1.972442e-3
GO:0009113 purine base biosynthetic process 1.995612e-3
GO:0031055 chromatin remodeling at centromere 2.024901e-3
GO:0021603 cranial nerve formation 2.058252e-3
GO:0070874 negative regulation of glycogen metabolic process 2.058252e-3
GO:0019322 pentose biosynthetic process 2.060774e-3
GO:0042723 thiamine-containing compound metabolic process 2.081340e-3
GO:0010039 response to iron ion 2.138532e-3
GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity 2.233390e-3
GO:0045654 positive regulation of megakaryocyte differentiation 2.267112e-3
GO:0006903 vesicle targeting 2.283252e-3
GO:0032853 positive regulation of Ran GTPase activity 2.283835e-3
GO:0010509 polyamine homeostasis 2.283835e-3
GO:0006927 transformed cell apoptosis 2.305818e-3
GO:0006885 regulation of pH 2.316502e-3
GO:0033084 regulation of immature T cell proliferation in thymus 2.355080e-3
GO:0061003 positive regulation of dendritic spine morphogenesis 2.370461e-3
GO:0016079 synaptic vesicle exocytosis 2.427056e-3
GO:0008295 spermidine biosynthetic process 2.428730e-3
GO:0070647 protein modification by small protein conjugation or removal 2.447321e-3
GO:0034351 negative regulation of glial cell apoptosis 2.448358e-3
GO:0050860 negative regulation of T cell receptor signaling pathway 2.477076e-3
GO:0006044 N-acetylglucosamine metabolic process 2.515153e-3
GO:0046718 entry of virus into host cell 2.554478e-3
GO:0016226 iron-sulfur cluster assembly 2.578935e-3
GO:0033108 mitochondrial respiratory chain complex assembly 2.628619e-3
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 2.684795e-3
GO:0051725 protein de-ADP-ribosylation 2.729298e-3
GO:0071872 cellular response to epinephrine stimulus 2.729298e-3
GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process 2.729298e-3
GO:0002051 osteoblast fate commitment 2.729298e-3
GO:0071158 positive regulation of cell cycle arrest 2.789662e-3
GO:0051972 regulation of telomerase activity 2.807424e-3
GO:0000389 nuclear mRNA 3'-splice site recognition 2.809148e-3
GO:0006788 heme oxidation 2.810312e-3
GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 2.814811e-3
GO:0006396 RNA processing 2.815825e-3
GO:0035176 social behavior 2.876175e-3
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 2.943266e-3
GO:0043029 T cell homeostasis 3.002200e-3
GO:0048102 autophagic cell death 3.031883e-3
GO:0085020 protein K6-linked ubiquitination 3.031883e-3
GO:0042997 negative regulation of Golgi to plasma membrane protein transport 3.031883e-3
GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 3.073101e-3
GO:0007220 Notch receptor processing 3.085407e-3
GO:0070170 regulation of tooth mineralization 3.152072e-3
GO:0000079 regulation of cyclin-dependent protein kinase activity 3.159014e-3
GO:0046814 virion attachment, binding of host cell surface coreceptor 3.163868e-3
GO:0006189 'de novo' IMP biosynthetic process 3.163868e-3
GO:0003014 renal system process 3.258063e-3
GO:0010610 regulation of mRNA stability involved in response to stress 3.263073e-3
GO:0032347 regulation of aldosterone biosynthetic process 3.414122e-3
GO:0045794 negative regulation of cell volume 3.501296e-3
GO:0070159 mitochondrial threonyl-tRNA aminoacylation 3.655806e-3
GO:0035344 hypoxanthine transport 3.655806e-3
GO:0035364 thymine transport 3.655806e-3
GO:0015854 guanine transport 3.655806e-3
GO:0006051 N-acetylmannosamine metabolic process 3.655806e-3
GO:0019303 D-ribose catabolic process 3.655806e-3
GO:0019230 proprioception 3.675709e-3
GO:0048103 somatic stem cell division 3.787810e-3
GO:0006351 transcription, DNA-dependent 3.807416e-3
GO:0033209 tumor necrosis factor-mediated signaling pathway 3.829818e-3
GO:0090161 Golgi ribbon formation 3.833986e-3
GO:0043984 histone H4-K16 acetylation 3.833986e-3
GO:0072348 sulfur compound transport 3.921364e-3
GO:0034641 cellular nitrogen compound metabolic process 4.042110e-3
GO:0033238 regulation of cellular amine metabolic process 4.091590e-3
GO:0006869 lipid transport 4.155144e-3
GO:0042118 endothelial cell activation 4.252451e-3
GO:0010107 potassium ion import 4.293170e-3
GO:0021849 neuroblast division in subventricular zone 4.300333e-3
GO:0050725 positive regulation of interleukin-1 beta biosynthetic process 4.352875e-3
GO:0050754 positive regulation of fractalkine biosynthetic process 4.352875e-3
GO:0031081 nuclear pore distribution 4.352875e-3
GO:0006425 glutaminyl-tRNA aminoacylation 4.352875e-3
GO:0043170 macromolecule metabolic process 4.354331e-3
GO:0008380 RNA splicing 4.378045e-3
GO:0072422 signal transduction involved in DNA damage checkpoint 4.406821e-3
GO:0045601 regulation of endothelial cell differentiation 4.525076e-3
GO:0044243 multicellular organismal catabolic process 4.548550e-3
GO:0072661 protein targeting to plasma membrane 4.730445e-3
GO:0007614 short-term memory 4.730743e-3
GO:0008588 release of cytoplasmic sequestered NF-kappaB 4.745639e-3
GO:0035635 entry of bacterium into host cell 4.855602e-3
GO:0052066 entry of symbiont into host cell by promotion of host phagocytosis 4.855602e-3
GO:0006021 inositol biosynthetic process 4.855602e-3
GO:0071870 cellular response to catecholamine stimulus 4.914174e-3
GO:0043628 ncRNA 3'-end processing 4.914174e-3
GO:0010923 negative regulation of phosphatase activity 4.970136e-3
GO:0051865 protein autoubiquitination 5.146210e-3
GO:0051187 cofactor catabolic process 5.300699e-3
GO:0032462 regulation of protein homooligomerization 5.437769e-3
GO:0070585 protein localization in mitochondrion 5.469196e-3
GO:0072395 signal transduction involved in cell cycle checkpoint 5.495191e-3
GO:0006987 activation of signaling protein activity involved in unfolded protein response 5.595866e-3
GO:0019062 virion attachment to host cell surface receptor 5.639010e-3
GO:0031069 hair follicle morphogenesis 5.728638e-3
GO:0048690 regulation of axon extension involved in regeneration 5.764215e-3
GO:0051648 vesicle localization 5.771804e-3
GO:0051220 cytoplasmic sequestering of protein 5.788774e-3
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway 5.843014e-3
GO:0006108 malate metabolic process 5.850952e-3
GO:0016570 histone modification 5.878358e-3
GO:0031576 G2/M transition checkpoint 5.905244e-3
GO:0032287 peripheral nervous system myelin maintenance 5.914100e-3
GO:0033687 osteoblast proliferation 5.941850e-3
GO:0060730 regulation of intestinal epithelial structure maintenance 5.941850e-3
GO:0046784 intronless viral mRNA export from host nucleus 5.976727e-3
GO:0032872 regulation of stress-activated MAPK cascade 6.070405e-3
GO:0050856 regulation of T cell receptor signaling pathway 6.128520e-3
GO:0019693 ribose phosphate metabolic process 6.251071e-3
GO:0010842 retina layer formation 6.252813e-3
GO:0090305 nucleic acid phosphodiester bond hydrolysis 6.263272e-3
GO:0043623 cellular protein complex assembly 6.278700e-3
GO:0010799 regulation of peptidyl-threonine phosphorylation 6.318151e-3
GO:0006261 DNA-dependent DNA replication 6.339539e-3
GO:0071258 cellular response to gravity 6.343827e-3
GO:2000098 negative regulation of smooth muscle cell-matrix adhesion 6.343827e-3
GO:0035491 positive regulation of leukotriene production involved in inflammatory response 6.343827e-3
GO:0061044 negative regulation of vascular wound healing 6.343827e-3
GO:0031573 intra-S DNA damage checkpoint 6.343827e-3
GO:2000649 regulation of sodium ion transmembrane transporter activity 6.433611e-3
GO:0006855 drug transmembrane transport 6.446547e-3
GO:0016568 chromatin modification 6.525203e-3
GO:0010677 negative regulation of cellular carbohydrate metabolic process 6.805729e-3
GO:0048532 anatomical structure arrangement 6.874377e-3
GO:0042482 positive regulation of odontogenesis 6.927582e-3
GO:0035883 enteroendocrine cell differentiation 6.977809e-3
GO:0006900 membrane budding 6.993721e-3
GO:0045844 positive regulation of striated muscle tissue development 7.045034e-3
GO:0007035 vacuolar acidification 7.070321e-3
GO:0002003 angiotensin maturation 7.131179e-3
GO:0030150 protein import into mitochondrial matrix 7.154286e-3
GO:0048560 establishment of anatomical structure orientation 7.168683e-3
GO:0047496 vesicle transport along microtubule 7.344325e-3
GO:0071455 cellular response to hyperoxia 7.351689e-3
GO:0032459 regulation of protein oligomerization 7.380351e-3
GO:0021557 oculomotor nerve development 7.537771e-3
GO:0048388 endosomal lumen acidification 7.590013e-3
GO:0021526 medial motor column neuron differentiation 7.590013e-3
GO:0044267 cellular protein metabolic process 7.593472e-3
GO:0000266 mitochondrial fission 7.656168e-3
GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway 7.716338e-3
GO:0010866 regulation of triglyceride biosynthetic process 7.750497e-3
GO:0000072 M phase specific microtubule process 7.755528e-3
GO:0006369 termination of RNA polymerase II transcription 7.805845e-3
GO:0031396 regulation of protein ubiquitination 7.833424e-3
GO:0033198 response to ATP 7.905604e-3
GO:0006397 mRNA processing 7.919963e-3
GO:0017148 negative regulation of translation 8.034662e-3
GO:0019067 viral assembly, maturation, egress, and release 8.049682e-3
GO:0018027 peptidyl-lysine dimethylation 8.049682e-3
GO:0032848 negative regulation of cellular pH reduction 8.073028e-3
GO:0043375 CD8-positive, alpha-beta T cell lineage commitment 8.073028e-3
GO:0021747 cochlear nucleus development 8.073028e-3
GO:0014042 positive regulation of neuron maturation 8.073028e-3
GO:2000249 regulation of actin cytoskeleton reorganization 8.166976e-3
GO:0046605 regulation of centrosome cycle 8.166976e-3
GO:0032507 maintenance of protein location in cell 8.281438e-3
GO:0019064 viral envelope fusion with host membrane 8.519328e-3
GO:0090209 negative regulation of triglyceride metabolic process 8.631780e-3
GO:0006610 ribosomal protein import into nucleus 8.651170e-3
GO:0018023 peptidyl-lysine trimethylation 8.651170e-3
GO:0006901 vesicle coating 8.667576e-3
GO:0060409 positive regulation of acetylcholine metabolic process 8.689056e-3
GO:0042986 positive regulation of amyloid precursor protein biosynthetic process 8.729691e-3
GO:0006534 cysteine metabolic process 8.808838e-3
GO:0046878 positive regulation of saliva secretion 8.904808e-3
GO:0097150 neuronal stem cell maintenance 8.941640e-3
GO:0031297 replication fork processing 9.017860e-3
GO:0045618 positive regulation of keratinocyte differentiation 9.089129e-3
GO:0033364 mast cell secretory granule organization 9.261105e-3
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 9.325715e-3
GO:0060456 positive regulation of digestive system process 9.482737e-3
GO:0006740 NADPH regeneration 9.503410e-3
GO:0051661 maintenance of centrosome location 9.520792e-3
GO:0070781 response to biotin 9.520792e-3
GO:0060904 regulation of protein folding in endoplasmic reticulum 9.520792e-3
GO:0035499 carnosine biosynthetic process 9.520792e-3
GO:0010983 positive regulation of high-density lipoprotein particle clearance 9.520792e-3
GO:0021589 cerebellum structural organization 9.520792e-3
GO:0060689 cell differentiation involved in salivary gland development 9.819341e-3
GO:0015853 adenine transport 9.819341e-3
GO:0043985 histone H4-R3 methylation 1.006758e-2
GO:0030187 melatonin biosynthetic process 1.009081e-2
GO:0060611 mammary gland fat development 1.027350e-2
GO:0046173 polyol biosynthetic process 1.027350e-2
GO:0006683 galactosylceramide catabolic process 1.027350e-2
GO:0008629 induction of apoptosis by intracellular signals 1.031140e-2
GO:0070979 protein K11-linked ubiquitination 1.048262e-2
GO:0034645 cellular macromolecule biosynthetic process 1.050015e-2
GO:0003407 neural retina development 1.061831e-2
GO:0008216 spermidine metabolic process 1.066953e-2
GO:0006313 transposition, DNA-mediated 1.066953e-2
GO:0007379 segment specification 1.087304e-2
GO:0001776 leukocyte homeostasis 1.102880e-2
GO:0017121 phospholipid scrambling 1.103020e-2
GO:2000706 negative regulation of dense core granule biogenesis 1.107430e-2
GO:2000798 negative regulation of amniotic stem cell differentiation 1.107430e-2
GO:0048291 isotype switching to IgG isotypes 1.107430e-2
GO:0018364 peptidyl-glutamine methylation 1.107430e-2


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 6.986783e-10
GO:0046985 positive regulation of hemoglobin biosynthetic process 6.986783e-10
GO:0043973 histone H3-K4 acetylation 6.986783e-10
GO:0051865 protein autoubiquitination 2.940070e-9
GO:0006904 vesicle docking involved in exocytosis 3.003167e-9
GO:0070078 histone H3-R2 demethylation 3.591778e-9
GO:0070079 histone H4-R3 demethylation 3.591778e-9
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 3.591778e-9
GO:0071169 establishment of protein localization to chromatin 4.688164e-9
GO:0048278 vesicle docking 2.135861e-8
GO:0016081 synaptic vesicle docking involved in exocytosis 2.150846e-8
GO:0032740 positive regulation of interleukin-17 production 2.844359e-8
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 3.538682e-8
GO:0060299 negative regulation of sarcomere organization 3.538682e-8
GO:0046984 regulation of hemoglobin biosynthetic process 9.212836e-8
GO:0046605 regulation of centrosome cycle 1.697973e-7
GO:0022406 membrane docking 3.205073e-7
GO:0005976 polysaccharide metabolic process 4.448004e-7
GO:0030203 glycosaminoglycan metabolic process 6.590610e-7
GO:0010824 regulation of centrosome duplication 1.116536e-6
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 1.814524e-6
GO:0018293 protein-FAD linkage 1.814524e-6
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 2.561488e-6
GO:0033299 secretion of lysosomal enzymes 2.935207e-6
GO:0006022 aminoglycan metabolic process 4.835454e-6
GO:0034509 centromeric core chromatin assembly 5.680481e-6
GO:0034080 CenH3-containing nucleosome assembly at centromere 5.680481e-6
GO:0032660 regulation of interleukin-17 production 6.050617e-6
GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein 6.116473e-6
GO:0006367 transcription initiation from RNA polymerase II promoter 8.006985e-6
GO:0071108 protein K48-linked deubiquitination 8.795717e-6
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 1.045259e-5
GO:0043932 ossification involved in bone remodeling 1.045259e-5
GO:0006913 nucleocytoplasmic transport 1.060159e-5
GO:0060319 primitive erythrocyte differentiation 1.240803e-5
GO:0032819 positive regulation of natural killer cell proliferation 1.661582e-5
GO:0006396 RNA processing 1.885515e-5
GO:0009817 defense response to fungus, incompatible interaction 1.897761e-5
GO:0051169 nuclear transport 2.098209e-5
GO:0006427 histidyl-tRNA aminoacylation 2.114483e-5
GO:0051026 chiasma assembly 2.568968e-5
GO:0019049 evasion of host defenses by virus 2.930238e-5
GO:0018126 protein hydroxylation 3.137210e-5
GO:0009992 cellular water homeostasis 4.250096e-5
GO:0006610 ribosomal protein import into nucleus 4.357937e-5
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 4.357937e-5
GO:0048692 negative regulation of axon extension involved in regeneration 4.773299e-5
GO:0021849 neuroblast division in subventricular zone 4.773299e-5
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 5.110913e-5
GO:0042231 interleukin-13 biosynthetic process 5.336202e-5
GO:2000256 positive regulation of male germ cell proliferation 5.336202e-5
GO:0006275 regulation of DNA replication 5.830476e-5
GO:0048285 organelle fission 5.883256e-5
GO:0032965 regulation of collagen biosynthetic process 6.288210e-5
GO:0046599 regulation of centriole replication 6.749769e-5
GO:0070120 ciliary neurotrophic factor-mediated signaling pathway 6.881456e-5
GO:0019221 cytokine-mediated signaling pathway 7.437498e-5
GO:0070534 protein K63-linked ubiquitination 7.635738e-5
GO:0072513 positive regulation of secondary heart field cardioblast proliferation 8.475802e-5
GO:0034332 adherens junction organization 1.026694e-4
GO:0045062 extrathymic T cell selection 1.056533e-4
GO:0048143 astrocyte activation 1.111071e-4
GO:0032078 negative regulation of endodeoxyribonuclease activity 1.136357e-4
GO:0006922 cleavage of lamin 1.136357e-4
GO:0032312 regulation of ARF GTPase activity 1.137740e-4
GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein 1.144646e-4
GO:0042866 pyruvate biosynthetic process 1.180290e-4
GO:0006352 transcription initiation, DNA-dependent 1.192905e-4
GO:0006397 mRNA processing 1.364381e-4
GO:0010950 positive regulation of endopeptidase activity 1.407960e-4
GO:0007093 mitotic cell cycle checkpoint 1.440013e-4
GO:0032967 positive regulation of collagen biosynthetic process 1.449582e-4
GO:0007183 SMAD protein complex assembly 1.578015e-4
GO:0033138 positive regulation of peptidyl-serine phosphorylation 1.625966e-4
GO:0006044 N-acetylglucosamine metabolic process 1.669122e-4
GO:0061034 olfactory bulb mitral cell layer development 1.769005e-4
GO:0010936 negative regulation of macrophage cytokine production 1.812069e-4
GO:0032816 positive regulation of natural killer cell activation 1.953076e-4
GO:0010614 negative regulation of cardiac muscle hypertrophy 2.016204e-4
GO:0070267 oncosis 2.151227e-4
GO:2000001 regulation of DNA damage checkpoint 2.151227e-4
GO:0090007 regulation of mitotic anaphase 2.182971e-4
GO:0035912 dorsal aorta morphogenesis 2.182971e-4
GO:0030038 contractile actin filament bundle assembly 2.182971e-4
GO:0034421 post-translational protein acetylation 2.182971e-4
GO:0014010 Schwann cell proliferation 2.204650e-4
GO:0007412 axon target recognition 2.204650e-4
GO:0046604 positive regulation of mitotic centrosome separation 2.349462e-4
GO:0007096 regulation of exit from mitosis 2.404723e-4
GO:0019532 oxalate transport 2.428366e-4
GO:0000398 nuclear mRNA splicing, via spliceosome 2.457420e-4
GO:0046463 acylglycerol biosynthetic process 2.458747e-4
GO:0046724 oxalic acid secretion 2.696218e-4
GO:0070370 cellular heat acclimation 2.696218e-4
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate 2.696218e-4
GO:0008535 respiratory chain complex IV assembly 2.707590e-4
GO:0003266 regulation of secondary heart field cardioblast proliferation 2.707607e-4
GO:0006366 transcription from RNA polymerase II promoter 2.786750e-4
GO:0008380 RNA splicing 2.851053e-4
GO:0097035 regulation of membrane lipid distribution 2.855079e-4
GO:0006090 pyruvate metabolic process 2.855278e-4
GO:0043486 histone exchange 2.882734e-4
GO:0042772 DNA damage response, signal transduction resulting in transcription 2.940238e-4
GO:0007184 SMAD protein import into nucleus 2.940238e-4
GO:0007406 negative regulation of neuroblast proliferation 3.179461e-4
GO:0000375 RNA splicing, via transesterification reactions 3.249902e-4
GO:0060743 epithelial cell maturation involved in prostate gland development 3.348980e-4
GO:0034441 plasma lipoprotein particle oxidation 3.363265e-4
GO:0007288 sperm axoneme assembly 3.462413e-4
GO:0070306 lens fiber cell differentiation 3.873599e-4
GO:0006289 nucleotide-excision repair 3.885465e-4
GO:0032817 regulation of natural killer cell proliferation 4.043158e-4
GO:0021794 thalamus development 4.238602e-4
GO:0008156 negative regulation of DNA replication 4.324379e-4
GO:0000075 cell cycle checkpoint 4.388269e-4
GO:0032012 regulation of ARF protein signal transduction 4.527526e-4
GO:0010735 positive regulation of transcription via serum response element binding 4.565757e-4
GO:0060427 lung connective tissue development 4.565757e-4
GO:0001672 regulation of chromatin assembly or disassembly 4.620876e-4
GO:0000278 mitotic cell cycle 4.872976e-4
GO:0008361 regulation of cell size 4.881705e-4
GO:0015722 canalicular bile acid transport 4.882859e-4
GO:0000733 DNA strand renaturation 4.918156e-4
GO:0043044 ATP-dependent chromatin remodeling 5.017575e-4
GO:0010889 regulation of sequestering of triglyceride 5.064221e-4
GO:0060215 primitive hemopoiesis 5.064221e-4
GO:0044260 cellular macromolecule metabolic process 5.415430e-4
GO:0046784 intronless viral mRNA export from host nucleus 5.724263e-4
GO:0010669 epithelial structure maintenance 5.818022e-4
GO:0001866 NK T cell proliferation 5.818904e-4
GO:0050916 sensory perception of sweet taste 6.059256e-4
GO:0046607 positive regulation of centrosome cycle 6.059256e-4
GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation 6.087620e-4
GO:0043951 negative regulation of cAMP-mediated signaling 6.087620e-4
GO:0038007 netrin-activated signaling pathway 6.210591e-4
GO:0031055 chromatin remodeling at centromere 6.210591e-4
GO:0032069 regulation of nuclease activity 6.327666e-4
GO:0014741 negative regulation of muscle hypertrophy 6.327666e-4
GO:0048535 lymph node development 6.749736e-4
GO:0014916 regulation of lung blood pressure 7.000776e-4
GO:0044246 regulation of multicellular organismal metabolic process 7.286534e-4
GO:0007049 cell cycle 7.348435e-4
GO:0021783 preganglionic parasympathetic nervous system development 7.814575e-4
GO:0046504 glycerol ether biosynthetic process 7.924751e-4
GO:0043415 positive regulation of skeletal muscle tissue regeneration 7.985761e-4
GO:0045216 cell-cell junction organization 8.044411e-4
GO:0090304 nucleic acid metabolic process 8.080757e-4
GO:0000738 DNA catabolic process, exonucleolytic 8.499405e-4
GO:0048024 regulation of nuclear mRNA splicing, via spliceosome 8.513495e-4
GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development 8.519677e-4
GO:0031536 positive regulation of exit from mitosis 8.519677e-4
GO:0070647 protein modification by small protein conjugation or removal 8.736816e-4
GO:0033135 regulation of peptidyl-serine phosphorylation 8.766718e-4
GO:0051142 positive regulation of NK T cell proliferation 9.322679e-4
GO:0051984 positive regulation of chromosome segregation 9.453529e-4
GO:0072537 fibroblast activation 9.453529e-4
GO:0071345 cellular response to cytokine stimulus 9.538091e-4
GO:0046655 folic acid metabolic process 9.735754e-4
GO:0032916 positive regulation of transforming growth factor beta3 production 9.735754e-4
GO:0044140 negative regulation of growth of symbiont on or near host surface 9.866674e-4
GO:0000087 M phase of mitotic cell cycle 1.019308e-3
GO:0016482 cytoplasmic transport 1.026245e-3
GO:0007067 mitosis 1.051678e-3
GO:0070936 protein K48-linked ubiquitination 1.094119e-3
GO:0016575 histone deacetylation 1.096807e-3
GO:0060075 regulation of resting membrane potential 1.186268e-3
GO:0007094 mitotic cell cycle spindle assembly checkpoint 1.186268e-3
GO:0032814 regulation of natural killer cell activation 1.191026e-3
GO:0006476 protein deacetylation 1.193862e-3
GO:0010165 response to X-ray 1.198127e-3
GO:0032446 protein modification by small protein conjugation 1.215111e-3
GO:0060742 epithelial cell differentiation involved in prostate gland development 1.225129e-3
GO:0018065 protein-cofactor linkage 1.277026e-3
GO:0006545 glycine biosynthetic process 1.277026e-3
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1.282338e-3
GO:0019432 triglyceride biosynthetic process 1.285803e-3
GO:0051451 myoblast migration 1.316315e-3
GO:0006784 heme a biosynthetic process 1.316315e-3
GO:0045162 clustering of voltage-gated sodium channels 1.316315e-3
GO:0006281 DNA repair 1.369511e-3
GO:0018364 peptidyl-glutamine methylation 1.373212e-3
GO:0048034 heme O biosynthetic process 1.373212e-3
GO:0000147 actin cortical patch assembly 1.373212e-3
GO:0071174 mitotic cell cycle spindle checkpoint 1.391152e-3
GO:0050684 regulation of mRNA processing 1.395366e-3
GO:0042482 positive regulation of odontogenesis 1.458075e-3
GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein 1.470293e-3
GO:0043543 protein acylation 1.530991e-3
GO:0035855 megakaryocyte development 1.623881e-3
GO:0071168 protein localization to chromatin 1.658014e-3
GO:0016998 cell wall macromolecule catabolic process 1.673152e-3
GO:0019048 virus-host interaction 1.680797e-3
GO:0043064 flagellum organization 1.681297e-3
GO:0061381 cell migration in diencephalon 1.685093e-3
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 1.685093e-3
GO:0061379 inferior colliculus development 1.685093e-3
GO:0042340 keratan sulfate catabolic process 1.685093e-3
GO:0021855 hypothalamus cell migration 1.685093e-3
GO:0061374 mammillothalamic axonal tract development 1.685093e-3
GO:2000297 negative regulation of synapse maturation 1.690702e-3
GO:0035601 protein deacylation 1.696044e-3
GO:0021884 forebrain neuron development 1.717838e-3
GO:0044253 positive regulation of multicellular organismal metabolic process 1.751030e-3
GO:0032781 positive regulation of ATPase activity 1.758231e-3
GO:0048672 positive regulation of collateral sprouting 1.784427e-3
GO:0030091 protein repair 1.784427e-3
GO:0009957 epidermal cell fate specification 1.784427e-3
GO:0016574 histone ubiquitination 1.823825e-3
GO:0070536 protein K63-linked deubiquitination 1.855658e-3
GO:0071156 regulation of cell cycle arrest 1.859137e-3
GO:0014732 skeletal muscle atrophy 1.920650e-3
GO:0043623 cellular protein complex assembly 1.924609e-3
GO:0016568 chromatin modification 1.926226e-3
GO:0032074 negative regulation of nuclease activity 1.950669e-3
GO:0010172 embryonic body morphogenesis 1.983294e-3
GO:0033280 response to vitamin D 2.028305e-3
GO:0060744 mammary gland branching involved in thelarche 2.085732e-3
GO:0045332 phospholipid translocation 2.149211e-3
GO:0048486 parasympathetic nervous system development 2.160018e-3
GO:0009296 flagellum assembly 2.254299e-3
GO:0006605 protein targeting 2.317403e-3
GO:0006974 response to DNA damage stimulus 2.337246e-3
GO:0046633 alpha-beta T cell proliferation 2.398258e-3
GO:0043949 regulation of cAMP-mediated signaling 2.398258e-3
GO:0048679 regulation of axon regeneration 2.519068e-3
GO:0030204 chondroitin sulfate metabolic process 2.533945e-3
GO:0002513 tolerance induction to self antigen 2.544640e-3
GO:0016925 protein sumoylation 2.553972e-3
GO:0006606 protein import into nucleus 2.625067e-3
GO:0007259 JAK-STAT cascade 2.628007e-3
GO:0071104 response to interleukin-9 2.665073e-3
GO:0060061 Spemann organizer formation 2.665073e-3
GO:0070179 D-serine biosynthetic process 2.665073e-3
GO:0032071 regulation of endodeoxyribonuclease activity 2.687261e-3
GO:0016559 peroxisome fission 2.813422e-3
GO:0002031 G-protein coupled receptor internalization 2.822397e-3
GO:0021695 cerebellar cortex development 2.847412e-3
GO:0060947 cardiac vascular smooth muscle cell differentiation 2.881902e-3
GO:0001702 gastrulation with mouth forming second 2.909770e-3
GO:0016322 neuron remodeling 3.096999e-3
GO:0007341 penetration of zona pellucida 3.119425e-3
GO:0046532 regulation of photoreceptor cell differentiation 3.137030e-3
GO:0046668 regulation of retinal cell programmed cell death 3.203183e-3
GO:0051276 chromosome organization 3.352061e-3
GO:0051101 regulation of DNA binding 3.413356e-3
GO:0014889 muscle atrophy 3.458358e-3
GO:0017038 protein import 3.468417e-3
GO:0016567 protein ubiquitination 3.529253e-3
GO:0010529 negative regulation of transposition 3.548309e-3
GO:0070383 DNA cytosine deamination 3.548309e-3
GO:0003349 epicardium-derived cardiac endothelial cell differentiation 3.548309e-3
GO:0042481 regulation of odontogenesis 3.575077e-3
GO:0016340 calcium-dependent cell-matrix adhesion 3.605961e-3
GO:0042095 interferon-gamma biosynthetic process 3.605961e-3
GO:0002642 positive regulation of immunoglobulin biosynthetic process 3.605961e-3
GO:0006601 creatine biosynthetic process 3.605961e-3
GO:0001830 trophectodermal cell fate commitment 3.605961e-3
GO:0051438 regulation of ubiquitin-protein ligase activity 3.725295e-3
GO:0022403 cell cycle phase 3.775517e-3
GO:0022028 tangential migration from the subventricular zone to the olfactory bulb 3.807134e-3
GO:0010467 gene expression 3.887028e-3
GO:0071894 histone H2B conserved C-terminal lysine ubiquitination 3.974631e-3
GO:0000053 argininosuccinate metabolic process 3.974631e-3
GO:0043484 regulation of RNA splicing 4.111460e-3
GO:0006418 tRNA aminoacylation for protein translation 4.113833e-3
GO:0006425 glutaminyl-tRNA aminoacylation 4.174048e-3
GO:0046533 negative regulation of photoreceptor cell differentiation 4.207715e-3
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 4.226624e-3
GO:0072107 positive regulation of ureteric bud formation 4.276101e-3
GO:0051592 response to calcium ion 4.292080e-3
GO:0019835 cytolysis 4.383783e-3
GO:0010611 regulation of cardiac muscle hypertrophy 4.383783e-3
GO:0033561 regulation of water loss via skin 4.416645e-3
GO:0045647 negative regulation of erythrocyte differentiation 4.438437e-3
GO:0043117 positive regulation of vascular permeability 4.505699e-3
GO:0015808 L-alanine transport 4.505699e-3
GO:0072428 signal transduction involved in intra-S DNA damage checkpoint 4.648564e-3
GO:0035048 splicing factor protein import into nucleus 4.648564e-3
GO:0021564 vagus nerve development 4.675364e-3
GO:0010564 regulation of cell cycle process 4.706965e-3
GO:0035520 monoubiquitinated protein deubiquitination 4.729756e-3
GO:0006654 phosphatidic acid biosynthetic process 4.838715e-3
GO:0043248 proteasome assembly 4.839706e-3
GO:0051340 regulation of ligase activity 4.839985e-3
GO:0006513 protein monoubiquitination 5.002998e-3
GO:0010763 positive regulation of fibroblast migration 5.096356e-3
GO:0045136 development of secondary sexual characteristics 5.220116e-3
GO:0016577 histone demethylation 5.220116e-3
GO:0044339 canonical Wnt receptor signaling pathway involved in osteoblast differentiation 5.362306e-3
GO:0042297 vocal learning 5.362306e-3
GO:0044338 canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation 5.362306e-3
GO:0051170 nuclear import 5.391552e-3
GO:0016071 mRNA metabolic process 5.457505e-3
GO:0000266 mitochondrial fission 5.491827e-3
GO:0051603 proteolysis involved in cellular protein catabolic process 5.561527e-3
GO:0046602 regulation of mitotic centrosome separation 5.658984e-3
GO:0005977 glycogen metabolic process 5.696009e-3
GO:0015884 folic acid transport 5.701663e-3
GO:0006302 double-strand break repair 5.786962e-3
GO:0016032 viral reproduction 5.793640e-3
GO:0006998 nuclear envelope organization 5.936641e-3
GO:0060119 inner ear receptor cell development 6.046031e-3
GO:0034622 cellular macromolecular complex assembly 6.047727e-3
GO:0032070 regulation of deoxyribonuclease activity 6.081329e-3
GO:0030997 regulation of centriole-centriole cohesion 6.081329e-3
GO:0044257 cellular protein catabolic process 6.104506e-3
GO:0051301 cell division 6.399489e-3
GO:0072193 ureter smooth muscle cell differentiation 6.481905e-3
GO:0072053 renal inner medulla development 6.602764e-3
GO:0006596 polyamine biosynthetic process 6.602764e-3
GO:0045906 negative regulation of vasoconstriction 6.602764e-3
GO:0006325 chromatin organization 6.627737e-3
GO:0070507 regulation of microtubule cytoskeleton organization 6.821859e-3
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 6.849783e-3
GO:0014743 regulation of muscle hypertrophy 6.872189e-3
GO:0071173 spindle assembly checkpoint 6.885416e-3
GO:0048680 positive regulation of axon regeneration 6.885416e-3
GO:0006659 phosphatidylserine biosynthetic process 6.885416e-3
GO:0060081 membrane hyperpolarization 7.056806e-3
GO:0030212 hyaluronan metabolic process 7.113151e-3
GO:0006473 protein acetylation 7.221353e-3
GO:0032695 negative regulation of interleukin-12 production 7.326018e-3
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 7.341525e-3
GO:0015791 polyol transport 7.341525e-3
GO:0022415 viral reproductive process 7.343128e-3
GO:2000826 regulation of heart morphogenesis 7.348097e-3
GO:0002070 epithelial cell maturation 7.389239e-3
GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway 7.433799e-3
GO:0051782 negative regulation of cell division 7.682763e-3
GO:0042350 GDP-L-fucose biosynthetic process 7.682763e-3
GO:0042178 xenobiotic catabolic process 7.698267e-3
GO:0050829 defense response to Gram-negative bacterium 7.731020e-3
GO:0055107 Golgi to secretory granule transport 7.744976e-3
GO:0031468 nuclear envelope reassembly 7.744976e-3
GO:0010826 negative regulation of centrosome duplication 7.744976e-3
GO:0006021 inositol biosynthetic process 7.744976e-3
GO:0051660 establishment of centrosome localization 7.759747e-3
GO:0021540 corpus callosum morphogenesis 7.759747e-3
GO:0072560 type B pancreatic cell maturation 7.759747e-3
GO:0010845 positive regulation of reciprocal meiotic recombination 7.759747e-3
GO:0006421 asparaginyl-tRNA aminoacylation 7.759747e-3
GO:0006429 leucyl-tRNA aminoacylation 7.759747e-3
GO:0090102 cochlea development 7.767506e-3
GO:0051152 positive regulation of smooth muscle cell differentiation 7.780209e-3
GO:0050917 sensory perception of umami taste 7.957844e-3
GO:0072332 signal transduction by p53 class mediator resulting in induction of apoptosis 8.140217e-3
GO:0030104 water homeostasis 8.214079e-3
GO:0071072 negative regulation of phospholipid biosynthetic process 8.285493e-3
GO:0031065 positive regulation of histone deacetylation 8.507344e-3
GO:0052200 response to host defenses 8.597496e-3
GO:0035082 axoneme assembly 8.597496e-3
GO:0010891 negative regulation of sequestering of triglyceride 8.597496e-3
GO:0006482 protein demethylation 8.652839e-3
GO:0019255 glucose 1-phosphate metabolic process 8.666869e-3
GO:0000209 protein polyubiquitination 8.676833e-3
GO:0043502 regulation of muscle adaptation 8.707294e-3
GO:0044264 cellular polysaccharide metabolic process 9.078708e-3
GO:0071425 hemopoietic stem cell proliferation 9.094016e-3
GO:0071305 cellular response to vitamin D 9.202601e-3
GO:0033119 negative regulation of RNA splicing 9.223423e-3
GO:0045930 negative regulation of mitotic cell cycle 9.343625e-3
GO:0006906 vesicle fusion 9.442617e-3
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 9.495153e-3
GO:0032928 regulation of superoxide anion generation 9.543757e-3
GO:0048670 regulation of collateral sprouting 9.543757e-3
GO:0071474 cellular hyperosmotic response 9.555282e-3
GO:0021930 cerebellar granule cell precursor proliferation 9.555282e-3
GO:0009070 serine family amino acid biosynthetic process 9.842944e-3
GO:0006290 pyrimidine dimer repair 9.872039e-3
GO:0060710 chorio-allantoic fusion 9.880994e-3
GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis 1.014039e-2
GO:0060971 embryonic heart tube left/right pattern formation 1.031436e-2
GO:0022408 negative regulation of cell-cell adhesion 1.033289e-2
GO:0034201 response to oleic acid 1.042986e-2
GO:0090312 positive regulation of protein deacetylation 1.043411e-2
GO:0006835 dicarboxylic acid transport 1.043411e-2
GO:0072199 regulation of mesenchymal cell proliferation involved in ureter development 1.044652e-2
GO:0044265 cellular macromolecule catabolic process 1.079950e-2
GO:0006886 intracellular protein transport 1.083748e-2
GO:0033211 adiponectin-mediated signaling pathway 1.100928e-2
GO:0045987 positive regulation of smooth muscle contraction 1.114810e-2
GO:0060547 negative regulation of necrotic cell death 1.119093e-2
GO:0035811 negative regulation of urine volume 1.123278e-2
GO:0035886 vascular smooth muscle cell differentiation 1.124235e-2
GO:0070498 interleukin-1-mediated signaling pathway 1.134354e-2
GO:0018205 peptidyl-lysine modification 1.153502e-2
GO:0009057 macromolecule catabolic process 1.156184e-2
GO:0007109 cytokinesis, completion of separation 1.157283e-2
GO:0071071 regulation of phospholipid biosynthetic process 1.167365e-2
GO:0051001 negative regulation of nitric-oxide synthase activity 1.167365e-2
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 1.167365e-2
GO:0060064 Spemann organizer formation at the anterior end of the primitive streak 1.179996e-2
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential 1.179996e-2
GO:0042073 intraflagellar transport 1.179996e-2
GO:0007630 jump response 1.179996e-2
GO:0008049 male courtship behavior 1.179996e-2
GO:0001966 thigmotaxis 1.179996e-2
GO:0034971 histone H3-R17 methylation 1.198290e-2
GO:0033260 DNA replication involved in S phase 1.198290e-2
GO:0006997 nucleus organization 1.210955e-2
GO:0016573 histone acetylation 1.215100e-2
GO:0006096 glycolysis 1.221641e-2
GO:0005975 carbohydrate metabolic process 1.239288e-2
GO:0051894 positive regulation of focal adhesion assembly 1.254754e-2
GO:0045792 negative regulation of cell size 1.263530e-2
GO:0045657 positive regulation of monocyte differentiation 1.263530e-2
GO:0002309 T cell proliferation involved in immune response 1.263530e-2
GO:0034508 centromere complex assembly 1.263530e-2
GO:0071277 cellular response to calcium ion 1.265805e-2
GO:0007224 smoothened signaling pathway 1.285129e-2
GO:0031577 spindle checkpoint 1.292103e-2
GO:0030501 positive regulation of bone mineralization 1.296368e-2
GO:0051901 positive regulation of mitochondrial depolarization 1.300521e-2
GO:0043654 recognition of apoptotic cell 1.300521e-2
GO:0046135 pyrimidine nucleoside catabolic process 1.300521e-2
GO:0048681 negative regulation of axon regeneration 1.318328e-2
GO:0048690 regulation of axon extension involved in regeneration 1.318328e-2
GO:0032119 sequestering of zinc ion 1.318328e-2
GO:0045081 negative regulation of interleukin-10 biosynthetic process 1.318328e-2
GO:0009107 lipoate biosynthetic process 1.335570e-2
GO:0006526 arginine biosynthetic process 1.335570e-2
GO:0021885 forebrain cell migration 1.346533e-2
GO:0009072 aromatic amino acid family metabolic process 1.361039e-2
GO:0006403 RNA localization 1.384933e-2
GO:0034621 cellular macromolecular complex subunit organization 1.392066e-2
GO:0001836 release of cytochrome c from mitochondria 1.403543e-2
GO:0070988 demethylation 1.412746e-2
GO:0006689 ganglioside catabolic process 1.419279e-2
GO:0033962 cytoplasmic mRNA processing body assembly 1.421159e-2
GO:0090403 oxidative stress-induced premature senescence 1.421159e-2
GO:0032910 regulation of transforming growth factor beta3 production 1.421159e-2
GO:0048172 regulation of short-term neuronal synaptic plasticity 1.422514e-2
GO:0050913 sensory perception of bitter taste 1.444618e-2
GO:0034504 protein localization to nucleus 1.473668e-2
GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis 1.478552e-2
GO:0007339 binding of sperm to zona pellucida 1.482253e-2
GO:0006884 cell volume homeostasis 1.482253e-2
GO:0006821 chloride transport 1.495167e-2
GO:0021860 pyramidal neuron development 1.497655e-2
GO:0045040 protein import into mitochondrial outer membrane 1.512396e-2
GO:0032328 alanine transport 1.512396e-2
GO:0002268 follicular dendritic cell differentiation 1.512396e-2
GO:0031987 locomotion involved in locomotory behavior 1.512396e-2
GO:0032075 positive regulation of nuclease activity 1.512396e-2
GO:0070169 positive regulation of biomineral tissue development 1.517767e-2
GO:0006383 transcription from RNA polymerase III promoter 1.535871e-2
GO:0048733 sebaceous gland development 1.535871e-2
GO:0070537 histone H2A K63-linked deubiquitination 1.535871e-2
GO:0010890 positive regulation of sequestering of triglyceride 1.535871e-2
GO:0032825 positive regulation of natural killer cell differentiation 1.536826e-2
GO:0034645 cellular macromolecule biosynthetic process 1.565539e-2
GO:0006259 DNA metabolic process 1.574428e-2
GO:0007221 positive regulation of transcription of Notch receptor target 1.592614e-2
GO:0050654 chondroitin sulfate proteoglycan metabolic process 1.595428e-2
GO:0051028 mRNA transport 1.627362e-2
GO:0048066 developmental pigmentation 1.636261e-2
GO:0051354 negative regulation of oxidoreductase activity 1.652642e-2
GO:0045839 negative regulation of mitosis 1.661077e-2
GO:0008637 apoptotic mitochondrial changes 1.664149e-2
GO:0046543 development of secondary female sexual characteristics 1.682354e-2
GO:0048697 positive regulation of collateral sprouting in absence of injury 1.685740e-2
GO:0070885 negative regulation of calcineurin-NFAT signaling pathway 1.685740e-2
GO:0070163 regulation of adiponectin secretion 1.685740e-2
GO:0048478 replication fork protection 1.685740e-2
GO:0000059 protein import into nucleus, docking 1.685740e-2
GO:0006597 spermine biosynthetic process 1.685740e-2
GO:0022029 telencephalon cell migration 1.688266e-2
GO:0046511 sphinganine biosynthetic process 1.691185e-2
GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter 1.691185e-2
GO:0090177 establishment of planar polarity involved in neural tube closure 1.691185e-2
GO:0046416 D-amino acid metabolic process 1.691185e-2
GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development 1.691185e-2
GO:0006931 substrate-dependent cell migration, cell attachment to substrate 1.691185e-2
GO:0035633 maintenance of blood-brain barrier 1.691185e-2
GO:0015826 threonine transport 1.691185e-2
GO:0003061 positive regulation of the force of heart contraction by norepinephrine 1.691185e-2
GO:0034589 hydroxyproline transport 1.691185e-2
GO:0048298 positive regulation of isotype switching to IgA isotypes 1.716270e-2
GO:0032747 positive regulation of interleukin-23 production 1.716270e-2
GO:0042384 cilium assembly 1.750674e-2
GO:0021557 oculomotor nerve development 1.767597e-2
GO:0060364 frontal suture morphogenesis 1.774285e-2
GO:0017004 cytochrome complex assembly 1.777048e-2
GO:0030071 regulation of mitotic metaphase/anaphase transition 1.777643e-2
GO:0006863 purine base transport 1.778514e-2
GO:0046716 muscle cell homeostasis 1.785766e-2
GO:0021756 striatum development 1.850009e-2
GO:0043632 modification-dependent macromolecule catabolic process 1.937279e-2
GO:0002344 B cell affinity maturation 1.938763e-2
GO:0000086 G2/M transition of mitotic cell cycle 1.941550e-2
GO:0044267 cellular protein metabolic process 1.957887e-2
GO:0060982 coronary artery morphogenesis 1.979460e-2
GO:0030163 protein catabolic process 1.979902e-2
GO:0043114 regulation of vascular permeability 1.982008e-2
GO:0021702 cerebellar Purkinje cell differentiation 2.024849e-2
GO:0035066 positive regulation of histone acetylation 2.027185e-2
GO:0042401 cellular biogenic amine biosynthetic process 2.036390e-2
GO:2000171 negative regulation of dendrite development 2.042938e-2
GO:0033523 histone H2B ubiquitination 2.043840e-2
GO:0000080 G1 phase of mitotic cell cycle 2.069479e-2