DOID:1036

Name:	chronic leukemia
Namespace:	FANTOM
Definition:	"A leukemia that develops slowly." [url:http://www.nlm.nih.gov/medlineplus/leukemiaadultchronic.html]
Xrefs:	Expandlinks: UMLS_CUI:C0085670
Synonyms:	"adult chronic leukemia" RELATED [] "CLL" RELATED [] "CML" RELATED []

Ontology association<br>Each term has an is_a parent in the Disease Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to DISEASE ontologies.<br><br>link to ontology dataset<br>data

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Parents

is_a:	DOID:1240(leukemia)

Children

is a:	DOID:1040 (chronic lymphocytic leukemia)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples

Human (Homo sapiens)

• 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
• 10416-106C2 (chronic lymphocytic leukemia (T-CLL) cell line:SKW-3)
• 10454-106G4 (chronic myelogenous leukemia cell line:K562)
• 10725-110A5
• 10752-110D5 (leukemia, chronic megakaryoblastic cell line:MEG-01)
• 10801-110I9 (chronic myeloblastic leukemia (CML) cell line:KCL-22)
• 10824-111C5 (chronic myelogenous leukemia cell line:K562 ENCODE, biol_rep1)
• 10825-111C6 (chronic myelogenous leukemia cell line:K562 ENCODE, biol_rep2)
• 10826-111C7 (chronic myelogenous leukemia cell line:K562 ENCODE, biol_rep3)

Mouse (Mus musculus)

• 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
• 10416-106C2 (chronic lymphocytic leukemia (T-CLL) cell line:SKW-3)
• 10454-106G4 (chronic myelogenous leukemia cell line:K562)
• 10725-110A5
• 10752-110D5 (leukemia, chronic megakaryoblastic cell line:MEG-01)
• 10801-110I9 (chronic myeloblastic leukemia (CML) cell line:KCL-22)
• 10824-111C5 (chronic myelogenous leukemia cell line:K562 ENCODE, biol_rep1)
• 10825-111C6 (chronic myelogenous leukemia cell line:K562 ENCODE, biol_rep2)
• 10826-111C7 (chronic myelogenous leukemia cell line:K562 ENCODE, biol_rep3)

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with DOID:1036 (chronic leukemia), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

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P-value	FFCP	Short description

P-value	FFCP	Short description
8.98e-147	FFCP PHASE1:Hg19::chr1:65946823..65946834,-	p@chr1:65946823..65946834, -
8.98e-147	FFCP PHASE2:Hg19::chr1:65946823..65946834,-	p@chr1:65946823..65946834, -
4.36e-126	FFCP PHASE1:Hg19::chr1:15104171..15104180,-	p@chr1:15104171..15104180, -
4.36e-126	FFCP PHASE2:Hg19::chr1:65946781..65946791,-	p@chr1:65946781..65946791, -
4.36e-126	FFCP PHASE2:Hg19::chr1:15104171..15104180,-	p@chr1:15104171..15104180, -
4.36e-126	FFCP PHASE1:Hg19::chr1:65946781..65946791,-	p@chr1:65946781..65946791, -
1.5e-122	FFCP PHASE2:Hg19::chr4:10187460..10187471,-	p@chr4:10187460..10187471, -
1.5e-122	FFCP PHASE2:Hg19::chr4:10187482..10187491,-	p@chr4:10187482..10187491, -
1.5e-122	FFCP PHASE1:Hg19::chr4:10187460..10187471,-	p@chr4:10187460..10187471, -
1.5e-122	FFCP PHASE2:Hg19::chr4:127656639..127656648,-	p@chr4:127656639..127656648, -
1.5e-122	FFCP PHASE1:Hg19::chr4:10187482..10187491,-	p@chr4:10187482..10187491, -
1.5e-122	FFCP PHASE1:Hg19::chr4:127656639..127656648,-	p@chr4:127656639..127656648, -
1.76e-120	FFCP PHASE1:Hg19::chr6:143485995..143486013,+	p7@AIG1
1.76e-120	FFCP PHASE2:Hg19::chr6:143485995..143486013,+	p7@AIG1
2.54e-110	FFCP PHASE2:Hg19::chr21:16126130..16126154,-	p2@ENST00000455253
2.54e-110	FFCP PHASE1:Hg19::chr21:16126130..16126154,-	p2@ENST00000455253
3.07e-110	FFCP PHASE2:Hg19::chr21:16126181..16126192,-	p4@ENST00000455253
3.07e-110	FFCP PHASE1:Hg19::chr21:16126181..16126192,-	p4@ENST00000455253
5.4e-110	FFCP PHASE1:Hg19::chr14:93460574..93460583,-	p@chr14:93460574..93460583, -
5.4e-110	FFCP PHASE2:Hg19::chr14:93460574..93460583,-	p@chr14:93460574..93460583, -
1.53e-109	FFCP PHASE2:Hg19::chr6:143485971..143485982,+	p13@AIG1
1.53e-109	FFCP PHASE1:Hg19::chr6:143485971..143485982,+	p13@AIG1
1.77e-102	FFCP PHASE2:Hg19::chr6:37465165..37465170,+	p@chr6:37465165..37465170, +
1.77e-102	FFCP PHASE2:Hg19::chr7:106650705..106650710,+	p@chr7:106650705..106650710, +
1.77e-102	FFCP PHASE1:Hg19::chr14:76724603..76724631,+	p@chr14:76724603..76724631, +
1.77e-102	FFCP PHASE2:Hg19::chr4:127656623..127656632,-	p@chr4:127656623..127656632, -
1.77e-102	FFCP PHASE2:Hg19::chr14:76724603..76724631,+	p@chr14:76724603..76724631, +
1.77e-102	FFCP PHASE2:Hg19::chr21:16135200..16135219,-	p@chr21:16135200..16135219, -
1.77e-102	FFCP PHASE1:Hg19::chr6:37465165..37465170,+	p@chr6:37465165..37465170, +
1.77e-102	FFCP PHASE2:Hg19::chr15:55529745..55529773,-	p@chr15:55529745..55529773, -
1.77e-102	FFCP PHASE1:Hg19::chr15:55529745..55529773,-	p@chr15:55529745..55529773, -
1.77e-102	FFCP PHASE1:Hg19::chr4:127656623..127656632,-	p@chr4:127656623..127656632, -
1.77e-102	FFCP PHASE1:Hg19::chr7:106650705..106650710,+	p@chr7:106650705..106650710, +
1.77e-102	FFCP PHASE1:Hg19::chr21:16135200..16135219,-	p@chr21:16135200..16135219, -
1.77e-102	FFCP PHASE1:Hg19::chr15:34950105..34950148,+	p@chr15:34950105..34950148, +
1.77e-102	FFCP PHASE2:Hg19::chr15:34950105..34950148,+	p@chr15:34950105..34950148, +
2.19e-102	FFCP PHASE2:Hg19::chr9:101836652..101836660,+	p@chr9:101836652..101836660, +
2.19e-102	FFCP PHASE1:Hg19::chr9:101836652..101836660,+	p@chr9:101836652..101836660, +
2.7e-102	FFCP PHASE2:Hg19::chrX:65219618..65219630,+	p1@ENST00000424241
2.7e-102	FFCP PHASE1:Hg19::chrX:65219618..65219630,+	p1@ENST00000424241
4.1e-102	FFCP PHASE1:Hg19::chr6:68596655..68596664,-	p@chr6:68596655..68596664, -
4.1e-102	FFCP PHASE2:Hg19::chr6:68596655..68596664,-	p@chr6:68596655..68596664, -
5.05e-102	FFCP PHASE1:Hg19::chr10:63524414..63524429,-	p@chr10:63524414..63524429, -
5.05e-102	FFCP PHASE2:Hg19::chr10:63524414..63524429,-	p@chr10:63524414..63524429, -
4.87e-100	FFCP PHASE1:Hg19::chr6:68598674..68598685,-	p@chr6:68598674..68598685, -
4.87e-100	FFCP PHASE2:Hg19::chr6:68598674..68598685,-	p@chr6:68598674..68598685, -
1.36e-99	FFCP PHASE2:Hg19::chr6:68597965..68597975,-	p@chr6:68597965..68597975, -
1.36e-99	FFCP PHASE1:Hg19::chr6:68597965..68597975,-	p@chr6:68597965..68597975, -
2.02e-98	FFCP PHASE2:Hg19::chr6:68591719..68591728,-	p@chr6:68591719..68591728, -
2.02e-98	FFCP PHASE1:Hg19::chr6:68591719..68591728,-	p@chr6:68591719..68591728, -
2.02e-98	FFCP PHASE2:Hg19::chr15:91192144..91192162,+	p@chr15:91192144..91192162, +
2.02e-98	FFCP PHASE1:Hg19::chr15:91192144..91192162,+	p@chr15:91192144..91192162, +
2.26e-98	FFCP PHASE2:Hg19::chr8:130703341..130703361,-	p@chr8:130703341..130703361, -
2.26e-98	FFCP PHASE2:Hg19::chr21:16135169..16135180,-	p@chr21:16135169..16135180, -
2.26e-98	FFCP PHASE1:Hg19::chr3:132029141..132029151,+	p@chr3:132029141..132029151, +
2.26e-98	FFCP PHASE2:Hg19::chr12:23874501..23874508,-	p@chr12:23874501..23874508, -
2.26e-98	FFCP PHASE2:Hg19::chr9:132620675..132620685,+	p@chr9:132620675..132620685, +
2.26e-98	FFCP PHASE2:Hg19::chr21:16125690..16125700,-	p3@ENST00000454128
2.26e-98	FFCP PHASE1:Hg19::chr9:132620630..132620639,+	p@chr9:132620630..132620639, +
2.26e-98	FFCP PHASE2:Hg19::chr2:226321257..226321288,-	p@chr2:226321257..226321288, -
2.26e-98	FFCP PHASE2:Hg19::chr3:38060565..38060575,-	p13@PLCD1
2.26e-98	FFCP PHASE1:Hg19::chr3:38060516..38060530,-	p10@PLCD1
2.26e-98	FFCP PHASE2:Hg19::chrX:89713597..89713607,+	p@chrX:89713597..89713607, +
2.26e-98	FFCP PHASE1:Hg19::chr9:132620647..132620657,+	p@chr9:132620647..132620657, +
2.26e-98	FFCP PHASE1:Hg19::chr21:16135169..16135180,-	p@chr21:16135169..16135180, -
2.26e-98	FFCP PHASE1:Hg19::chr21:16125690..16125700,-	p3@ENST00000454128
2.26e-98	FFCP PHASE1:Hg19::chr3:38060540..38060563,-	p7@PLCD1
2.26e-98	FFCP PHASE1:Hg19::chr8:130703341..130703361,-	p@chr8:130703341..130703361, -
2.26e-98	FFCP PHASE1:Hg19::chr9:132620675..132620685,+	p@chr9:132620675..132620685, +
2.26e-98	FFCP PHASE2:Hg19::chr4:10187518..10187525,-	p@chr4:10187518..10187525, -
2.26e-98	FFCP PHASE2:Hg19::chr21:25263242..25263269,+	p@chr21:25263242..25263269, +
2.26e-98	FFCP PHASE1:Hg19::chrX:89713597..89713607,+	p@chrX:89713597..89713607, +
2.26e-98	FFCP PHASE1:Hg19::chr2:226321257..226321288,-	p@chr2:226321257..226321288, -
2.26e-98	FFCP PHASE1:Hg19::chr3:38060565..38060575,-	p13@PLCD1
2.26e-98	FFCP PHASE2:Hg19::chr9:132620630..132620639,+	p@chr9:132620630..132620639, +
2.26e-98	FFCP PHASE2:Hg19::chr3:38060516..38060530,-	p10@PLCD1
2.26e-98	FFCP PHASE1:Hg19::chr12:23874396..23874433,-	p@chr12:23874396..23874433, -
2.26e-98	FFCP PHASE2:Hg19::chr3:132029141..132029151,+	p@chr3:132029141..132029151, +
2.26e-98	FFCP PHASE1:Hg19::chr4:10187518..10187525,-	p@chr4:10187518..10187525, -
2.26e-98	FFCP PHASE2:Hg19::chr12:23874396..23874433,-	p@chr12:23874396..23874433, -
2.26e-98	FFCP PHASE2:Hg19::chr9:132620647..132620657,+	p@chr9:132620647..132620657, +
2.26e-98	FFCP PHASE2:Hg19::chr3:38060540..38060563,-	p7@PLCD1
2.26e-98	FFCP PHASE1:Hg19::chr21:25263242..25263269,+	p@chr21:25263242..25263269, +
2.26e-98	FFCP PHASE1:Hg19::chr12:23874501..23874508,-	p@chr12:23874501..23874508, -
2.82e-98	FFCP PHASE2:Hg19::chr15:58838947..58838952,+	p@chr15:58838947..58838952, +
2.82e-98	FFCP PHASE1:Hg19::chr15:58838947..58838952,+	p@chr15:58838947..58838952, +
4.63e-93	FFCP PHASE1:Hg19::chr6:68598190..68598207,-	p@chr6:68598190..68598207, -
4.63e-93	FFCP PHASE2:Hg19::chr6:68598190..68598207,-	p@chr6:68598190..68598207, -
6.97e-93	FFCP PHASE2:Hg19::chr6:68597994..68598005,-	p@chr6:68597994..68598005, -
6.97e-93	FFCP PHASE1:Hg19::chr6:68597994..68598005,-	p@chr6:68597994..68598005, -
9.18e-92	FFCP PHASE2:Hg19::chr6:68597240..68597258,-	p@chr6:68597240..68597258, -
9.18e-92	FFCP PHASE1:Hg19::chr6:68597240..68597258,-	p@chr6:68597240..68597258, -
5.77e-89	FFCP PHASE1:Hg19::chr15:34949928..34949947,+	p@chr15:34949928..34949947, +
5.77e-89	FFCP PHASE2:Hg19::chr15:34949928..34949947,+	p@chr15:34949928..34949947, +
6.71e-89	FFCP PHASE1:Hg19::chr1:15104189..15104213,-	p@chr1:15104189..15104213, -
6.71e-89	FFCP PHASE2:Hg19::chr1:15104189..15104213,-	p@chr1:15104189..15104213, -
7.81e-89	FFCP PHASE2:Hg19::chr6:68592711..68592723,-	p@chr6:68592711..68592723, -
7.81e-89	FFCP PHASE1:Hg19::chr6:68592711..68592723,-	p@chr6:68592711..68592723, -
1.06e-88	FFCP PHASE2:Hg19::chr7:16301644..16301664,+	p@chr7:16301644..16301664, +
1.06e-88	FFCP PHASE1:Hg19::chr7:16301644..16301664,+	p@chr7:16301644..16301664, +

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