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MCL coexpression mm9:120

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Phase1 CAGE Peaks

  Short description
Mm9::chr10:24636490..24636494,- p@chr10:24636490..24636494
-
Mm9::chr10:61533762..61533768,+ p1@Gm5424
Mm9::chr10:61534567..61534573,- p@chr10:61534567..61534573
-
Mm9::chr10:86981676..86981681,+ p@chr10:86981676..86981681
+
Mm9::chr10:87044592..87044623,+ p@chr10:87044592..87044623
+
Mm9::chr10:92951511..92951519,+ p2@Hal
Mm9::chr11:110112946..110112955,- p4@Abca6
Mm9::chr11:110113007..110113018,- p3@Abca6
Mm9::chr11:11797704..11797711,- p@chr11:11797704..11797711
-
Mm9::chr11:86652224..86652228,- -
p@chr11:86652224..86652228
Mm9::chr11:98912753..98912767,+ p@chr11:98912753..98912767
+
Mm9::chr13:52275630..52275635,+ p@chr13:52275630..52275635
+
Mm9::chr13:94407519..94407531,- p1@Bhmt
Mm9::chr14:41918648..41918667,+ p1@Mat1a
Mm9::chr14:41918833..41918858,+ p3@Mat1a
Mm9::chr15:96859705..96859708,- p@chr15:96859705..96859708
-
Mm9::chr16:4790187..4790203,- p5@5730403B10Rik
Mm9::chr16:4790205..4790216,- p6@5730403B10Rik
Mm9::chr17:31772973..31772975,+ p@chr17:31772973..31772975
+
Mm9::chr17:43804462..43804486,+ p1@Cyp39a1
Mm9::chr17:85076302..85076305,- p@chr17:85076302..85076305
-
Mm9::chr18:21119777..21119791,+ p7@Rnf125
Mm9::chr18:21119803..21119851,+ p4@Rnf125
Mm9::chr18:21119857..21119882,+ p3@Rnf125
Mm9::chr19:46747553..46747562,- p2@Cyp17a1
Mm9::chr19:58529905..58529948,- p10@Gfra1
Mm9::chr19:58529971..58529985,- p9@Gfra1
Mm9::chr1:164913185..164913187,+ p@chr1:164913185..164913187
+
Mm9::chr1:177555683..177555707,- p2@Fh1
Mm9::chr1:67163084..67163097,- p@chr1:67163084..67163097
-
Mm9::chr1:67170213..67170233,+ p@chr1:67170213..67170233
+
Mm9::chr1:67223896..67223900,+ p@chr1:67223896..67223900
+
Mm9::chr1:67256157..67256169,+ p@chr1:67256157..67256169
+
Mm9::chr2:172973544..172973561,- p@chr2:172973544..172973561
-
Mm9::chr2:172973623..172973653,- p@chr2:172973623..172973653
-
Mm9::chr2:172978561..172978581,+ p1@Pck1
Mm9::chr2:172979505..172979535,- p@chr2:172979505..172979535
-
Mm9::chr2:31315907..31315917,- p@chr2:31315907..31315917
-
Mm9::chr2:31315950..31315966,- p@chr2:31315950..31315966
-
Mm9::chr2:31317677..31317701,+ p@chr2:31317677..31317701
+
Mm9::chr2:31325808..31325830,+ p1@Ass1
Mm9::chr2:31344594..31344598,+ p@chr2:31344594..31344598
+
Mm9::chr2:31347835..31347858,+ p@chr2:31347835..31347858
+
Mm9::chr2:31365550..31365556,+ p@chr2:31365550..31365556
+
Mm9::chr2:31366452..31366457,+ p@chr2:31366452..31366457
+
Mm9::chr2:5598001..5598015,- -
p@chr2:5598001..5598015
Mm9::chr2:5598029..5598039,- p@chr2:5598029..5598039
-
Mm9::chr2:58642586..58642602,+ p@chr2:58642586..58642602
+
Mm9::chr2:65391875..65391885,+ p@chr2:65391875..65391885
+
Mm9::chr2:65391906..65391913,+ p@chr2:65391906..65391913
+
Mm9::chr3:130320482..130320501,+ p1@Agxt2l1
Mm9::chr3:157572560..157572571,- p@chr3:157572560..157572571
-
Mm9::chr3:157587823..157587841,- p2@Cth
Mm9::chr3:157588020..157588034,- p1@Cth
Mm9::chr4:115168734..115168752,- p1@Cyp4a14
Mm9::chr4:120647611..120647628,- p@chr4:120647611..120647628
-
Mm9::chr4:134474281..134474330,- p@chr4:134474281..134474330
-
Mm9::chr4:154951564..154951575,+ p@chr4:154951564..154951575
+
Mm9::chr4:49420914..49420917,- p@chr4:49420914..49420917
-
Mm9::chr5:120922826..120922839,- p2@Sdsl
Mm9::chr5:120926531..120926547,+ p1@Sds
Mm9::chr5:123621970..123621996,- p@chr5:123621970..123621996
-
Mm9::chr5:128113285..128113316,- p2@Slc15a4
Mm9::chr5:128113630..128113633,- p3@Slc15a4
Mm9::chr5:128137865..128137870,+ p@chr5:128137865..128137870
+
Mm9::chr5:130499098..130499103,- p@chr5:130499098..130499103
-
Mm9::chr5:130500150..130500227,- p1@Asl
Mm9::chr5:146691632..146691633,- p2@Cyp3a11
Mm9::chr5:77380741..77380820,+ p1@Paics
Mm9::chr5:77380824..77380836,+ p3@Paics
Mm9::chr5:93579160..93579171,+ p@chr5:93579160..93579171
+
Mm9::chr6:117129226..117129253,+ +
p@chr6:117129226..117129253
Mm9::chr6:141824569..141824571,+ p@chr6:141824569..141824571
+
Mm9::chr6:23082920..23082956,- p1@Aass
Mm9::chr6:23082981..23082992,- p2@Aass
Mm9::chr6:82020755..82020763,+ p@chr6:82020755..82020763
+
Mm9::chr6:90313294..90313311,+ p@chr6:90313294..90313311
+
Mm9::chr6:90424291..90424301,+ p@chr6:90424291..90424301
+
Mm9::chr6:90509385..90509408,+ p@chr6:90509385..90509408
+
Mm9::chr7:133819724..133819745,- p@chr7:133819724..133819745
-
Mm9::chr7:51722034..51722044,+ p@chr7:51722034..51722044
+
Mm9::chr7:71042282..71042311,+ p@chr7:71042282..71042311
+
Mm9::chr8:108659769..108659789,+ p@chr8:108659769..108659789
+
Mm9::chr8:24303998..24304003,- p@chr8:24303998..24304003
-
Mm9::chr8:41741374..41741380,- p@chr8:41741374..41741380
-
Mm9::chr8:41947593..41947602,- p@chr8:41947593..41947602
-
Mm9::chr8:73247486..73247504,- p@chr8:73247486..73247504
-
Mm9::chr8:87417057..87417068,- p5@Gcdh
Mm9::chr9:44609861..44609874,- p@chr9:44609861..44609874
-
Mm9::chr9:48413084..48413105,- p1@Nnmt
Mm9::chr9:48413112..48413123,- p4@Nnmt
Mm9::chr9:48413178..48413189,- p7@Nnmt
Mm9::chr9:48413190..48413205,- p2@Nnmt
Mm9::chr9:48413209..48413221,- p3@Nnmt
Mm9::chr9:48413225..48413238,- p5@Nnmt
Mm9::chr9:48413252..48413263,- p6@Nnmt
Mm9::chr9:62193194..62193212,+ +
p@chr9:62193194..62193212
Mm9::chr9:65083686..65083691,+ p@chr9:65083686..65083691
+
Mm9::chrX:7770513..7770523,- p4@Ebp


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0016829lyase activity2.46406878638975e-10
GO:0019752carboxylic acid metabolic process1.2404802186074e-06
GO:0006082organic acid metabolic process1.2404802186074e-06
GO:0006091generation of precursor metabolites and energy7.92913539539709e-06
GO:0016840carbon-nitrogen lyase activity7.92913539539709e-06
GO:0008652amino acid biosynthetic process1.26490130989831e-05
GO:0009058biosynthetic process1.53056571506228e-05
GO:0006520amino acid metabolic process2.59911923358682e-05
GO:0030170pyridoxal phosphate binding2.59911923358682e-05
GO:0009309amine biosynthetic process6.43907994795791e-05
GO:0044249cellular biosynthetic process7.10973083443533e-05
GO:0006519amino acid and derivative metabolic process9.5383920542986e-05
GO:0048037cofactor binding0.00012744799389119
GO:0044271nitrogen compound biosynthetic process0.00012744799389119
GO:0006118electron transport0.000141647593964036
GO:0016841ammonia-lyase activity0.000155522459834056
GO:0009308amine metabolic process0.000160458010606437
GO:0006807nitrogen compound metabolic process0.000230437964436646
GO:0019842vitamin binding0.00033980490175647
GO:0020037heme binding0.00037633594414303
GO:0046906tetrapyrrole binding0.00037633594414303
GO:0006526arginine biosynthetic process0.00037633594414303
GO:0004497monooxygenase activity0.00053449510275727
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen0.00053449510275727
GO:0019627urea metabolic process0.000642777348977239
GO:0043603amide metabolic process0.000642777348977239
GO:0000050urea cycle0.000642777348977239
GO:0006525arginine metabolic process0.00106061135412257
GO:0008395steroid hydroxylase activity0.0012362505274919
GO:0000051urea cycle intermediate metabolic process0.0012362505274919
GO:0000097sulfur amino acid biosynthetic process0.00146089729155016
GO:0006694steroid biosynthetic process0.00174465485454436
GO:0009084glutamine family amino acid biosynthetic process0.00194270274309554
GO:0005737cytoplasm0.002810280143802
GO:0000096sulfur amino acid metabolic process0.002810280143802
GO:0006094gluconeogenesis0.00309368757756801
GO:0008610lipid biosynthetic process0.00402957280668468
GO:0006090pyruvate metabolic process0.00450910727413831
GO:0006066alcohol metabolic process0.00504642292494655
GO:0019319hexose biosynthetic process0.00515137287684028
GO:0046165alcohol biosynthetic process0.00580687030955077
GO:0046364monosaccharide biosynthetic process0.00580687030955077
GO:0016831carboxy-lyase activity0.00613887745983948
GO:0016491oxidoreductase activity0.00626029196735565
GO:0044272sulfur compound biosynthetic process0.00730801525626199
GO:0005506iron ion binding0.00739981816291079
GO:0009064glutamine family amino acid metabolic process0.00748999174324632
GO:0008202steroid metabolic process0.00787578791194636
GO:0016874ligase activity0.00787578791194636
GO:0016830carbon-carbon lyase activity0.00787578791194636
GO:0005792microsome0.00787578791194636
GO:0047131saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity0.00787578791194636
GO:0004055argininosuccinate synthase activity0.00787578791194636
GO:0006114glycerol biosynthetic process0.00787578791194636
GO:0004638phosphoribosylaminoimidazole carboxylase activity0.00787578791194636
GO:0006106fumarate metabolic process0.00787578791194636
GO:0046173polyol biosynthetic process0.00787578791194636
GO:0004361glutaryl-CoA dehydrogenase activity0.00787578791194636
GO:0004508steroid 17-alpha-monooxygenase activity0.00787578791194636
GO:0004639phosphoribosylaminoimidazolesuccinocarboxamide synthase activity0.00787578791194636
GO:0048873homeostasis of number of cells within a tissue0.00787578791194636
GO:0003941L-serine ammonia-lyase activity0.00787578791194636
GO:0004753saccharopine dehydrogenase activity0.00787578791194636
GO:0004333fumarate hydratase activity0.00787578791194636
GO:0004123cystathionine gamma-lyase activity0.00787578791194636
GO:0004397histidine ammonia-lyase activity0.00787578791194636
GO:0042450arginine biosynthetic process via ornithine0.00787578791194636
GO:0004056argininosuccinate lyase activity0.00787578791194636
GO:0008112nicotinamide N-methyltransferase activity0.00787578791194636
GO:0046327glycerol biosynthetic process from pyruvate0.00787578791194636
GO:0009320phosphoribosylaminoimidazole carboxylase complex0.00787578791194636
GO:003378224-hydroxycholesterol 7alpha-hydroxylase activity0.00787578791194636
GO:0008387steroid 7-alpha-hydroxylase activity0.00787578791194636
GO:0006113fermentation0.00787578791194636
GO:0042598vesicular fraction0.00824337815197385
GO:0016879ligase activity, forming carbon-nitrogen bonds0.00843522879042755
GO:0005739mitochondrion0.00981543386523978
GO:0009063amino acid catabolic process0.010582881590535
GO:0044248cellular catabolic process0.0122609094705967
GO:0047750cholestenol delta-isomerase activity0.0122609094705967
GO:0006591ornithine metabolic process0.0122609094705967
GO:0008898homocysteine S-methyltransferase activity0.0122609094705967
GO:0046040IMP metabolic process0.0122609094705967
GO:0030573bile acid catabolic process0.0122609094705967
GO:0004613phosphoenolpyruvate carboxykinase (GTP) activity0.0122609094705967
GO:0006189'de novo' IMP biosynthetic process0.0122609094705967
GO:0000247C-8 sterol isomerase activity0.0122609094705967
GO:0045239tricarboxylic acid cycle enzyme complex0.0122609094705967
GO:0019794nonprotein amino acid metabolic process0.0122609094705967
GO:0006188IMP biosynthetic process0.0122609094705967
GO:0004478methionine adenosyltransferase activity0.0122609094705967
GO:0019344cysteine biosynthetic process0.0122609094705967
GO:0018685alkane 1-monooxygenase activity0.0122609094705967
GO:0004611phosphoenolpyruvate carboxykinase activity0.0122609094705967
GO:0008396oxysterol 7-alpha-hydroxylase activity0.0122609094705967
GO:0044270nitrogen compound catabolic process0.0125473985545729
GO:0009310amine catabolic process0.0125473985545729
GO:0006790sulfur metabolic process0.0142223492718431
GO:0032787monocarboxylic acid metabolic process0.0148347419016172
GO:0008203cholesterol metabolic process0.0158173818357916
GO:0046914transition metal ion binding0.0159525915927521
GO:0015980energy derivation by oxidation of organic compounds0.0164695349675379
GO:0033209tumor necrosis factor-mediated signaling pathway0.0166279563798225
GO:0016211ammonia ligase activity0.0166279563798225
GO:0016842amidine-lyase activity0.0166279563798225
GO:0008757S-adenosylmethionine-dependent methyltransferase activity0.0177781319082378
GO:0016125sterol metabolic process0.018106007904119
GO:0044262cellular carbohydrate metabolic process0.0204057587870693
GO:0000267cell fraction0.0204057587870693
GO:0019432triacylglycerol biosynthetic process0.0204057587870693
GO:0016880acid-ammonia (or amide) ligase activity0.0204057587870693
GO:0006707cholesterol catabolic process0.0204057587870693
GO:0016127sterol catabolic process0.0204057587870693
GO:0006699bile acid biosynthetic process0.0204057587870693
GO:0016051carbohydrate biosynthetic process0.0207356150081891
GO:0044255cellular lipid metabolic process0.020968864745525
GO:0009056catabolic process0.0238026026116236
GO:0016713oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen0.0240144692517739
GO:0006704glucocorticoid biosynthetic process0.0240144692517739
GO:0006527arginine catabolic process0.0240144692517739
GO:0006534cysteine metabolic process0.0240144692517739
GO:0006706steroid catabolic process0.0276541221097614
GO:0016054organic acid catabolic process0.0276541221097614
GO:0009070serine family amino acid biosynthetic process0.0276541221097614
GO:0008172S-methyltransferase activity0.0276541221097614
GO:0046395carboxylic acid catabolic process0.0276541221097614
GO:0006006glucose metabolic process0.0279149010725896
GO:0044444cytoplasmic part0.0282629873680856
GO:0006629lipid metabolic process0.030614312507511
GO:0046460neutral lipid biosynthetic process0.0307747231217011
GO:0005941unlocalized protein complex0.0307747231217011
GO:0046463acylglycerol biosynthetic process0.0307747231217011
GO:0046504glycerol ether biosynthetic process0.033863387649073
GO:0006857oligopeptide transport0.033863387649073
GO:0045017glycerolipid biosynthetic process0.033863387649073
GO:0009086methionine biosynthetic process0.033863387649073
GO:0006555methionine metabolic process0.033863387649073
GO:0009065glutamine family amino acid catabolic process0.0362186283449585
GO:0042771DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis0.0362186283449585
GO:0006548histidine catabolic process0.0362186283449585
GO:0043648dicarboxylic acid metabolic process0.0362186283449585
GO:0009077histidine family amino acid catabolic process0.0362186283449585
GO:0008211glucocorticoid metabolic process0.0362186283449585
GO:0016846carbon-sulfur lyase activity0.0362186283449585
GO:0005975carbohydrate metabolic process0.038614812289494
GO:0006547histidine metabolic process0.0388648302020247
GO:0009168purine ribonucleoside monophosphate biosynthetic process0.0388648302020247
GO:0009075histidine family amino acid metabolic process0.0388648302020247
GO:0009127purine nucleoside monophosphate biosynthetic process0.0388648302020247
GO:0019318hexose metabolic process0.04106720573231
GO:0008206bile acid metabolic process0.04106720573231
GO:0009167purine ribonucleoside monophosphate metabolic process0.04106720573231
GO:0009126purine nucleoside monophosphate metabolic process0.04106720573231
GO:0050897cobalt ion binding0.04106720573231
GO:0016646oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor0.04106720573231
GO:0005996monosaccharide metabolic process0.0420603793328592
GO:0005783endoplasmic reticulum0.0421169627800431
GO:0009067aspartate family amino acid biosynthetic process0.0439187036121171
GO:0030330DNA damage response, signal transduction by p53 class mediator0.0469504729316484
GO:0009156ribonucleoside monophosphate biosynthetic process0.0469504729316484
GO:0044424intracellular part0.047539792919115
GO:0006700C21-steroid hormone biosynthetic process0.0492937774659894
GO:0009161ribonucleoside monophosphate metabolic process0.0492937774659894
GO:0009066aspartate family amino acid metabolic process0.0492937774659894



Relative expression of the co-expression cluster over median
Analyst:





Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
metabolising cell1.26e-095
endopolyploid cell1.26e-095
parenchymal cell1.26e-095
polyploid cell1.26e-095
hepatocyte1.26e-095

Uber Anatomy
Ontology termp-valuen
liver3.77e-2622
epithelial sac3.77e-2622
digestive gland3.77e-2622
epithelium of foregut-midgut junction3.77e-2622
anatomical boundary3.77e-2622
hepatobiliary system3.77e-2622
foregut-midgut junction3.77e-2622
hepatic diverticulum3.77e-2622
liver primordium3.77e-2622
septum transversum3.77e-2622
liver bud3.77e-2622
digestive tract diverticulum7.39e-2523
sac7.39e-2523
exocrine gland1.39e-2225
exocrine system1.39e-2225
abdomen element3.80e-1849
abdominal segment element3.80e-1849
abdominal segment of trunk3.80e-1849
abdomen3.80e-1849
mesenchyme1.17e-1361
entire embryonic mesenchyme1.17e-1361
trunk mesenchyme1.43e-1245
subdivision of trunk2.84e-1266
epithelial tube2.31e-1047
trunk region element1.69e-0979
endocrine gland1.65e-0860
gut epithelium2.33e-0855
trunk8.69e-0890
gland1.40e-0765


TFBS overrepresentationSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.23958e-07
MA0004.10.918618
MA0006.10.0181544
MA0007.12.09923
MA0009.10.968397
MA0014.10.000622476
MA0017.11.77598
MA0019.10.267505
MA0024.11.7818
MA0025.11.07965
MA0027.11.43248
MA0028.10.00831229
MA0029.10.451892
MA0030.11.71048
MA0031.11.5463
MA0038.10.733394
MA0040.11.0045
MA0041.11.24405
MA0042.11.42067
MA0043.10.121079
MA0046.11.07315
MA0048.10.00325561
MA0050.11.45825
MA0051.10.765293
MA0052.10.0872399
MA0055.10.0078335
MA0056.10
MA0057.10.0425324
MA0058.10.855517
MA0059.10.137037
MA0060.11.08697
MA0061.10.166346
MA0063.10
MA0066.10.0447636
MA0067.10.26661
MA0068.10.0489802
MA0069.10.294567
MA0070.10.594575
MA0071.11.81148
MA0072.11.45565
MA0073.13.32886e-12
MA0074.10.0944337
MA0076.10.00517167
MA0077.10.536689
MA0078.10.180169
MA0081.10.0434427
MA0083.10.383273
MA0084.10.519277
MA0087.11.12356
MA0088.10.00670682
MA0089.10
MA0090.10.225391
MA0091.10.989751
MA0092.10.535064
MA0093.11.68802
MA0095.10
MA0098.10
MA0100.10.0855528
MA0101.10.151281
MA0103.10.220139
MA0105.10.117918
MA0106.10.369858
MA0107.10.0676497
MA0108.20.300139
MA0109.10
MA0111.10.145121
MA0113.11.51766
MA0114.11.91726
MA0115.10.776172
MA0116.10.609296
MA0117.10.348218
MA0119.10.760647
MA0122.10.116491
MA0124.10.231301
MA0125.10.185604
MA0130.10
MA0131.10.261233
MA0132.10
MA0133.10
MA0135.10.430741
MA0136.10.233874
MA0139.10.00638282
MA0140.10.00507345
MA0141.12.47891
MA0142.10.673596
MA0143.10.346915
MA0144.13.59833
MA0145.10.185231
MA0146.10.000921524
MA0147.10.295299
MA0148.10.744773
MA0149.10.00336254
MA0062.20.032981
MA0035.20.806397
MA0039.20.00952053
MA0138.20.471207
MA0002.20.506078
MA0137.22.44094
MA0104.20.120988
MA0047.20.730685
MA0112.20.388047
MA0065.22.21897
MA0150.10.266295
MA0151.10
MA0152.10.476413
MA0153.10.886563
MA0154.10.886795
MA0155.10.353309
MA0156.10.5083
MA0157.10.59451
MA0158.10
MA0159.10.46179
MA0160.11.0234
MA0161.10
MA0162.19.90486e-06
MA0163.10.00724107
MA0164.10.641682
MA0080.20.125556
MA0018.20.964617
MA0099.21.08557
MA0079.29.97437e-06
MA0102.20.563914
MA0258.10.196441
MA0259.10.00608838
MA0442.10