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MCL coexpression mm9:1714

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Phase1 CAGE Peaks

  Short description
Mm9::chr18:36823760..36823778,+ p2@Eif4ebp3
Mm9::chr18:36823786..36823811,+ p1@Eif4ebp3
Mm9::chr18:36824975..36825001,+ p@chr18:36824975..36825001
+
Mm9::chr2:4816920..4816926,+ p@chr2:4816920..4816926
+
Mm9::chr6:22293710..22293720,- p10@Fam3c


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0008190eukaryotic initiation factor 4E binding0.00365236764732738
GO:0031369translation initiation factor binding0.00365236764732738
GO:0045947negative regulation of translational initiation0.00365236764732738
GO:0006446regulation of translational initiation0.00949615588305119
GO:0017148negative regulation of translation0.00949615588305119
GO:0031327negative regulation of cellular biosynthetic process0.00949615588305119
GO:0009890negative regulation of biosynthetic process0.0100179226898122
GO:0006413translational initiation0.0120528132361804
GO:0051248negative regulation of protein metabolic process0.015339944118775
GO:0022618protein-RNA complex assembly0.015339944118775
GO:0006417regulation of translation0.0253839551489253
GO:0031326regulation of cellular biosynthetic process0.0253839551489253
GO:0009889regulation of biosynthetic process0.0261284762462651
GO:0022613ribonucleoprotein complex biogenesis and assembly0.0295841779433518
GO:0051246regulation of protein metabolic process0.0336017823554119
GO:0031324negative regulation of cellular metabolic process0.0399934257382348
GO:0065003macromolecular complex assembly0.0401760441206012
GO:0009892negative regulation of metabolic process0.0401760441206012
GO:0022607cellular component assembly0.0427903704365829
GO:0006412translation0.0466772585328439



Relative expression of the co-expression cluster over median
Analyst:





Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
metabolising cell1.31e-095
endopolyploid cell1.31e-095
parenchymal cell1.31e-095
polyploid cell1.31e-095
hepatocyte1.31e-095

Uber Anatomy
Ontology termp-valuen
liver2.22e-1322
epithelial sac2.22e-1322
digestive gland2.22e-1322
epithelium of foregut-midgut junction2.22e-1322
anatomical boundary2.22e-1322
hepatobiliary system2.22e-1322
foregut-midgut junction2.22e-1322
hepatic diverticulum2.22e-1322
liver primordium2.22e-1322
septum transversum2.22e-1322
liver bud2.22e-1322
digestive tract diverticulum1.26e-1223
sac1.26e-1223
exocrine gland2.64e-1125
exocrine system2.64e-1125


TFBS overrepresentationSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0185483
MA0004.10.603793
MA0006.10.419915
MA0007.10.587678
MA0009.11.06266
MA0014.10.0502051
MA0017.10.449113
MA0019.10.874061
MA0024.11.01759
MA0025.11.30092
MA0027.12.72141
MA0028.10.43138
MA0029.10.995171
MA0030.11.00195
MA0031.10.965177
MA0038.10.757669
MA0040.11.07552
MA0041.10.522007
MA0042.10.507715
MA0043.11.1618
MA0046.11.09955
MA0048.10.205696
MA0050.10.645342
MA0051.10.767098
MA0052.11.08379
MA0055.10.602741
MA0056.10
MA0057.10.192781
MA0058.10.50032
MA0059.10.513699
MA0060.10.330907
MA0061.10.364227
MA0063.10
MA0066.11.76548
MA0067.11.41352
MA0068.10.197245
MA0069.11.08414
MA0070.11.07418
MA0071.10.644448
MA0072.11.06547
MA0073.10.000589538
MA0074.10.708108
MA0076.10.470037
MA0077.11.04318
MA0078.10.801834
MA0081.10.53877
MA0083.11.16099
MA0084.11.74401
MA0087.11.11687
MA0088.10.148348
MA0089.10
MA0090.10.566938
MA0091.10.617887
MA0092.10.567278
MA0093.10.440484
MA0095.10
MA0098.10
MA0100.10.695835
MA0101.10.523409
MA0103.10.460936
MA0105.10.248108
MA0106.10.809991
MA0107.10.454197
MA0108.20.897859
MA0109.10
MA0111.10.582193
MA0113.10.780358
MA0114.10.361633
MA0115.11.16466
MA0116.10.419688
MA0117.11.13165
MA0119.10.524046
MA0122.11.15196
MA0124.11.35963
MA0125.11.28445
MA0130.10
MA0131.10.869325
MA0132.10
MA0133.10
MA0135.11.19898
MA0136.10.729175
MA0139.10.295945
MA0140.10.695713
MA0141.10.482463
MA0142.10.950155
MA0143.10.797553
MA0144.10.365053
MA0145.10.157686
MA0146.10.0604336
MA0147.10.378658
MA0148.10.621195
MA0149.10.529387
MA0062.20.254018
MA0035.20.700704
MA0039.20.0511423
MA0138.20.861035
MA0002.20.809945
MA0137.20.479301
MA0104.20.315156
MA0047.20.75686
MA0112.20.47695
MA0065.20.158101
MA0150.10.587557
MA0151.10
MA0152.10.756973
MA0153.11.21594
MA0154.10.203217
MA0155.10.173445
MA0156.10.469089
MA0157.10.91689
MA0158.10
MA0159.10.389847
MA0160.10.624415
MA0161.10
MA0162.10.526186
MA0163.10.0644585
MA0164.10.729558
MA0080.20.455167
MA0018.20.739807
MA0099.20.854449
MA0079.22.95501e-05
MA0102.21.79669
MA0258.10.346619
MA0259.10.366802
MA0442.10