MCL coexpression mm9:1750
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity | 0.0161051764061131 |
| GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity | 0.0161051764061131 |
| GO:0008475 | procollagen-lysine 5-dioxygenase activity | 0.0161051764061131 |
| GO:0015012 | heparan sulfate proteoglycan biosynthetic process | 0.0225423057380206 |
| GO:0030201 | heparan sulfate proteoglycan metabolic process | 0.0225423057380206 |
| GO:0043410 | positive regulation of MAPKKK cascade | 0.0241498236359184 |
| GO:0030166 | proteoglycan biosynthetic process | 0.0268022710415322 |
| GO:0043408 | regulation of MAPKKK cascade | 0.0268022710415322 |
| GO:0031418 | L-ascorbic acid binding | 0.0268022710415322 |
| GO:0006029 | proteoglycan metabolic process | 0.0268022710415322 |
| GO:0015020 | glucuronosyltransferase activity | 0.0268022710415322 |
| GO:0005783 | endoplasmic reticulum | 0.0268022710415322 |
| GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | 0.0268022710415322 |
| GO:0001707 | mesoderm formation | 0.0268022710415322 |
| GO:0048332 | mesoderm morphogenesis | 0.0268022710415322 |
| GO:0001704 | formation of primary germ layer | 0.0268022710415322 |
| GO:0044272 | sulfur compound biosynthetic process | 0.0268022710415322 |
| GO:0008375 | acetylglucosaminyltransferase activity | 0.0268022710415322 |
| GO:0007498 | mesoderm development | 0.0414298065478486 |
| GO:0051213 | dioxygenase activity | 0.0414706873941803 |
| GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | 0.0414706873941803 |
| GO:0006790 | sulfur metabolic process | 0.0414706873941803 |
| GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | 0.0414706873941803 |
| GO:0007369 | gastrulation | 0.0414706873941803 |
| GO:0009967 | positive regulation of signal transduction | 0.0417313724965586 |
| GO:0048729 | tissue morphogenesis | 0.0462742073363588 |
| GO:0016051 | carbohydrate biosynthetic process | 0.0469265999411267 |
| GO:0008194 | UDP-glycosyltransferase activity | 0.0492412841194071 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| non-terminally differentiated cell | 1.15e-08 | 49 |
| migratory neural crest cell | 1.93e-07 | 10 |
| neuron associated cell | 1.93e-07 | 10 |
| glial cell (sensu Vertebrata) | 1.93e-07 | 10 |
| neuron associated cell (sensu Vertebrata) | 1.93e-07 | 10 |
| glial cell | 1.93e-07 | 10 |
| glioblast | 1.93e-07 | 10 |
| glioblast (sensu Vertebrata) | 1.93e-07 | 10 |
| oligodendrocyte precursor cell | 9.18e-07 | 8 |
| Ontology term | p-value | n |
|---|---|---|
| ectoderm-derived structure | 7.73e-07 | 95 |
| ectoderm | 7.73e-07 | 95 |
| presumptive ectoderm | 7.73e-07 | 95 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 1.79223 |
| MA0004.1 | 0.603793 |
| MA0006.1 | 0.419915 |
| MA0007.1 | 0.587678 |
| MA0009.1 | 1.06266 |
| MA0014.1 | 0.418772 |
| MA0017.1 | 0.449113 |
| MA0019.1 | 0.874061 |
| MA0024.1 | 1.01759 |
| MA0025.1 | 1.30092 |
| MA0027.1 | 2.72141 |
| MA0028.1 | 0.43138 |
| MA0029.1 | 0.995171 |
| MA0030.1 | 1.00195 |
| MA0031.1 | 0.965177 |
| MA0038.1 | 0.757669 |
| MA0040.1 | 1.07552 |
| MA0041.1 | 0.522007 |
| MA0042.1 | 0.507715 |
| MA0043.1 | 1.1618 |
| MA0046.1 | 1.09955 |
| MA0048.1 | 0.205696 |
| MA0050.1 | 0.645342 |
| MA0051.1 | 0.767098 |
| MA0052.1 | 1.08379 |
| MA0055.1 | 0.602741 |
| MA0056.1 | 0 |
| MA0057.1 | 0.562607 |
| MA0058.1 | 0.50032 |
| MA0059.1 | 0.513699 |
| MA0060.1 | 0.881183 |
| MA0061.1 | 0.364227 |
| MA0063.1 | 0 |
| MA0066.1 | 0.746072 |
| MA0067.1 | 1.41352 |
| MA0068.1 | 0.197245 |
| MA0069.1 | 1.08414 |
| MA0070.1 | 1.07418 |
| MA0071.1 | 0.644448 |
| MA0072.1 | 1.06547 |
| MA0073.1 | 0.310158 |
| MA0074.1 | 0.708108 |
| MA0076.1 | 0.470037 |
| MA0077.1 | 1.04318 |
| MA0078.1 | 0.801834 |
| MA0081.1 | 0.53877 |
| MA0083.1 | 1.16099 |
| MA0084.1 | 1.74401 |
| MA0087.1 | 1.11687 |
| MA0088.1 | 0.453686 |
| MA0089.1 | 0 |
| MA0090.1 | 1.39153 |
| MA0091.1 | 0.617887 |
| MA0092.1 | 0.567278 |
| MA0093.1 | 0.440484 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.695835 |
| MA0101.1 | 0.523409 |
| MA0103.1 | 0.460936 |
| MA0105.1 | 0.248108 |
| MA0106.1 | 0.809991 |
| MA0107.1 | 0.454197 |
| MA0108.2 | 0.897859 |
| MA0109.1 | 0 |
| MA0111.1 | 0.582193 |
| MA0113.1 | 0.780358 |
| MA0114.1 | 0.361633 |
| MA0115.1 | 1.16466 |
| MA0116.1 | 1.89177 |
| MA0117.1 | 1.13165 |
| MA0119.1 | 0.524046 |
| MA0122.1 | 1.15196 |
| MA0124.1 | 1.35963 |
| MA0125.1 | 1.28445 |
| MA0130.1 | 0 |
| MA0131.1 | 0.869325 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.19898 |
| MA0136.1 | 0.729175 |
| MA0139.1 | 1.45902 |
| MA0140.1 | 0.695713 |
| MA0141.1 | 0.482463 |
| MA0142.1 | 0.950155 |
| MA0143.1 | 0.797553 |
| MA0144.1 | 0.365053 |
| MA0145.1 | 0.157686 |
| MA0146.1 | 0.822925 |
| MA0147.1 | 0.986917 |
| MA0148.1 | 0.621195 |
| MA0149.1 | 20.7523 |
| MA0062.2 | 0.254018 |
| MA0035.2 | 0.700704 |
| MA0039.2 | 1.8247 |
| MA0138.2 | 3.31401 |
| MA0002.2 | 0.809945 |
| MA0137.2 | 0.479301 |
| MA0104.2 | 1.52809 |
| MA0047.2 | 0.75686 |
| MA0112.2 | 2.12679 |
| MA0065.2 | 0.477991 |
| MA0150.1 | 0.587557 |
| MA0151.1 | 0 |
| MA0152.1 | 0.756973 |
| MA0153.1 | 1.21594 |
| MA0154.1 | 1.74374 |
| MA0155.1 | 2.24718 |
| MA0156.1 | 0.469089 |
| MA0157.1 | 0.91689 |
| MA0158.1 | 0 |
| MA0159.1 | 0.389847 |
| MA0160.1 | 0.624415 |
| MA0161.1 | 0 |
| MA0162.1 | 0.898893 |
| MA0163.1 | 0.230013 |
| MA0164.1 | 0.729558 |
| MA0080.2 | 0.455167 |
| MA0018.2 | 0.739807 |
| MA0099.2 | 0.854449 |
| MA0079.2 | 1.19329 |
| MA0102.2 | 1.79669 |
| MA0258.1 | 0.346619 |
| MA0259.1 | 0.960816 |
| MA0442.1 | 0 |
