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MCL coexpression mm9:1817

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Phase1 CAGE Peaks

 Short description
Mm9::chr5:92566966..92567000,+p1@Uso1
Mm9::chr9:44575875..44575921,-p1@Arcn1
Mm9::chr9:86465382..86465454,-p1@Pgm3
Mm9::chr9:98464123..98464156,+p1@Copb2
Mm9::chrX:136219519..136219621,+p1@Tbc1d8b


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0008565protein transporter activity0.000219104891027456
GO:0006886intracellular protein transport0.00111354618758562
GO:0016192vesicle-mediated transport0.00111354618758562
GO:0030117membrane coat0.00111354618758562
GO:0048475coated membrane0.00111354618758562
GO:0005794Golgi apparatus0.0019364197904871
GO:0046907intracellular transport0.0019364197904871
GO:0015031protein transport0.0019364197904871
GO:0045184establishment of protein localization0.0019364197904871
GO:0004610phosphoacetylglucosamine mutase activity0.0019364197904871
GO:0019255glucose 1-phosphate metabolic process0.0019364197904871
GO:0008104protein localization0.0019364197904871
GO:0051649establishment of cellular localization0.0019364197904871
GO:0051641cellular localization0.0019364197904871
GO:0033036macromolecule localization0.0019364197904871
GO:0006461protein complex assembly0.00202299057196888
GO:0006042glucosamine biosynthetic process0.00269868565779547
GO:0006045N-acetylglucosamine biosynthetic process0.00269868565779547
GO:0006048UDP-N-acetylglucosamine biosynthetic process0.00269868565779547
GO:0022892substrate-specific transporter activity0.00274667040158796
GO:0046349amino sugar biosynthetic process0.00366220096683051
GO:0004614phosphoglucomutase activity0.00445796520704365
GO:0006047UDP-N-acetylglucosamine metabolic process0.00445796520704365
GO:0019028viral capsid0.00533983193064862
GO:0065003macromolecular complex assembly0.00814726273194818
GO:0016868intramolecular transferase activity, phosphotransferases0.00823588975050593
GO:0030126COPI vesicle coat0.00823588975050593
GO:0030663COPI coated vesicle membrane0.00823588975050593
GO:0009225nucleotide-sugar metabolic process0.00883471110649204
GO:0022607cellular component assembly0.00909045551765844
GO:0030137COPI-coated vesicle0.00909045551765844
GO:0044423virion part0.0112053550578375
GO:0006041glucosamine metabolic process0.0135549638033076
GO:0006044N-acetylglucosamine metabolic process0.0135549638033076
GO:0006040amino sugar metabolic process0.0161628604484584
GO:0030119AP-type membrane coat adaptor complex0.0161628604484584
GO:0030120vesicle coat0.0161628604484584
GO:0030131clathrin adaptor complex0.0161628604484584
GO:0030662coated vesicle membrane0.0170579924476089
GO:0005798Golgi-associated vesicle0.0179079475735374
GO:0016866intramolecular transferase activity0.0180936511887276
GO:0006810transport0.019141762380073
GO:0016043cellular component organization and biogenesis0.0193196814823016
GO:0051234establishment of localization0.0193196814823016
GO:0030118clathrin coat0.0193196814823016
GO:0048471perinuclear region of cytoplasm0.0194539622026284
GO:0030659cytoplasmic vesicle membrane0.0206669543727467
GO:0051179localization0.0255386519276412
GO:0044433cytoplasmic vesicle part0.0255386519276412
GO:0012506vesicle membrane0.028586831706178
GO:0044444cytoplasmic part0.0377021893542771
GO:0016051carbohydrate biosynthetic process0.038703507010042
GO:0030135coated vesicle0.0417911382075104
GO:0006006glucose metabolic process0.0456942515727502



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
intestine4.60e-1131
endoderm-derived structure3.04e-09118
endoderm3.04e-09118
presumptive endoderm3.04e-09118
gastrointestinal system4.55e-0947
digestive system1.22e-08116
digestive tract1.22e-08116
primitive gut1.22e-08116
subdivision of digestive tract7.12e-08114
immaterial anatomical entity1.66e-0779


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.406907
MA0004.10.603793
MA0006.10.419915
MA0007.10.587678
MA0009.11.06266
MA0014.11.13011
MA0017.10.449113
MA0019.10.874061
MA0024.11.01759
MA0025.11.30092
MA0027.12.72141
MA0028.12.87883
MA0029.10.995171
MA0030.11.00195
MA0031.10.965177
MA0038.10.757669
MA0040.11.07552
MA0041.10.522007
MA0042.10.507715
MA0043.11.1618
MA0046.11.09955
MA0048.10.205696
MA0050.10.645342
MA0051.10.767098
MA0052.11.08379
MA0055.10.28842
MA0056.10
MA0057.10.192781
MA0058.11.25013
MA0059.11.27866
MA0060.10.881183
MA0061.10.364227
MA0063.10
MA0066.10.746072
MA0067.11.41352
MA0068.11.08757
MA0069.11.08414
MA0070.11.07418
MA0071.10.644448
MA0072.11.06547
MA0073.10.189951
MA0074.10.708108
MA0076.13.0561
MA0077.11.04318
MA0078.10.801834
MA0081.10.53877
MA0083.11.16099
MA0084.11.74401
MA0087.11.11687
MA0088.11.42769
MA0089.10
MA0090.10.566938
MA0091.10.617887
MA0092.10.567278
MA0093.11.12162
MA0095.10
MA0098.10
MA0100.10.695835
MA0101.10.523409
MA0103.10.460936
MA0105.10.248108
MA0106.10.809991
MA0107.10.454197
MA0108.20.897859
MA0109.10
MA0111.10.582193
MA0113.10.780358
MA0114.10.949408
MA0115.11.16466
MA0116.10.419688
MA0117.11.13165
MA0119.10.524046
MA0122.11.15196
MA0124.11.35963
MA0125.11.28445
MA0130.10
MA0131.12.01917
MA0132.10
MA0133.10
MA0135.11.19898
MA0136.10.729175
MA0139.10.295945
MA0140.10.695713
MA0141.10.482463
MA0142.10.950155
MA0143.10.797553
MA0144.10.956957
MA0145.10.157686
MA0146.10.822925
MA0147.10.378658
MA0148.10.621195
MA0149.10.529387
MA0062.23.69273
MA0035.20.700704
MA0039.22.75243
MA0138.20.861035
MA0002.20.809945
MA0137.21.20517
MA0104.20.315156
MA0047.20.75686
MA0112.20.927461
MA0065.20.929207
MA0150.10.587557
MA0151.10
MA0152.10.756973
MA0153.11.21594
MA0154.10.203217
MA0155.11.57585
MA0156.10.469089
MA0157.10.91689
MA0158.10
MA0159.11.01146
MA0160.10.624415
MA0161.10
MA0162.10.898893
MA0163.10.497328
MA0164.10.729558
MA0080.20.455167
MA0018.20.739807
MA0099.20.854449
MA0079.20.967156
MA0102.21.79669
MA0258.10.346619
MA0259.11.71005
MA0442.10
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