MCL coexpression mm9:2145
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr15:66978015..66978059,- | p@chr15:66978015..66978059 - |
| Mm9::chr18:32091124..32091174,+ | p1@Lims2 |
| Mm9::chr4:149377244..149377258,- | p3@H6pd |
| Mm9::chr4:149377276..149377303,- | p2@H6pd |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0047936 | glucose 1-dehydrogenase activity | 0.00777911685918377 |
| GO:0017057 | 6-phosphogluconolactonase activity | 0.00777911685918377 |
| GO:0004345 | glucose-6-phosphate dehydrogenase activity | 0.00777911685918377 |
| GO:0006098 | pentose-phosphate shunt | 0.0124448820561999 |
| GO:0006740 | NADPH regeneration | 0.0124448820561999 |
| GO:0006739 | NADP metabolic process | 0.0181458027245934 |
| GO:0006769 | nicotinamide metabolic process | 0.0226121789953236 |
| GO:0019362 | pyridine nucleotide metabolic process | 0.0226121789953236 |
| GO:0005925 | focal adhesion | 0.0226121789953236 |
| GO:0005924 | cell-substrate adherens junction | 0.0226121789953236 |
| GO:0006733 | oxidoreduction coenzyme metabolic process | 0.0226121789953236 |
| GO:0030055 | cell-matrix junction | 0.0226692001235209 |
| GO:0006767 | water-soluble vitamin metabolic process | 0.0233143341778803 |
| GO:0006007 | glucose catabolic process | 0.025343456383576 |
| GO:0046365 | monosaccharide catabolic process | 0.025343456383576 |
| GO:0019320 | hexose catabolic process | 0.025343456383576 |
| GO:0046164 | alcohol catabolic process | 0.025343456383576 |
| GO:0005912 | adherens junction | 0.025343456383576 |
| GO:0006766 | vitamin metabolic process | 0.025343456383576 |
| GO:0044275 | cellular carbohydrate catabolic process | 0.0254108027034711 |
| GO:0016323 | basolateral plasma membrane | 0.0254108027034711 |
| GO:0016052 | carbohydrate catabolic process | 0.0254108027034711 |
| GO:0006006 | glucose metabolic process | 0.032723093673353 |
| GO:0004091 | carboxylesterase activity | 0.0336162331405122 |
| GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 0.0341277797270279 |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors | 0.0354912718992774 |
| GO:0019318 | hexose metabolic process | 0.0370950229187441 |
| GO:0005996 | monosaccharide metabolic process | 0.0370950229187441 |
| GO:0005792 | microsome | 0.0397288219619067 |
| GO:0042598 | vesicular fraction | 0.0397288219619067 |
| GO:0006732 | coenzyme metabolic process | 0.0397288219619067 |
| GO:0009117 | nucleotide metabolic process | 0.0437860630783343 |
| GO:0051186 | cofactor metabolic process | 0.0438594544916371 |
| GO:0055086 | nucleobase, nucleoside and nucleotide metabolic process | 0.0441544680719521 |
| GO:0044265 | cellular macromolecule catabolic process | 0.0497044630990999 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| trunk | 1.17e-16 | 90 |
| trunk region element | 1.79e-15 | 79 |
| subdivision of trunk | 3.39e-15 | 66 |
| trunk mesenchyme | 1.30e-12 | 45 |
| abdomen element | 1.77e-12 | 49 |
| abdominal segment element | 1.77e-12 | 49 |
| abdominal segment of trunk | 1.77e-12 | 49 |
| abdomen | 1.77e-12 | 49 |
| mesenchyme | 1.17e-11 | 61 |
| entire embryonic mesenchyme | 1.17e-11 | 61 |
| exocrine gland | 3.17e-10 | 25 |
| exocrine system | 3.17e-10 | 25 |
| immaterial anatomical entity | 3.34e-10 | 79 |
| liver | 1.84e-09 | 22 |
| epithelial sac | 1.84e-09 | 22 |
| digestive gland | 1.84e-09 | 22 |
| epithelium of foregut-midgut junction | 1.84e-09 | 22 |
| anatomical boundary | 1.84e-09 | 22 |
| hepatobiliary system | 1.84e-09 | 22 |
| foregut-midgut junction | 1.84e-09 | 22 |
| hepatic diverticulum | 1.84e-09 | 22 |
| liver primordium | 1.84e-09 | 22 |
| septum transversum | 1.84e-09 | 22 |
| liver bud | 1.84e-09 | 22 |
| digestive tract diverticulum | 3.48e-09 | 23 |
| sac | 3.48e-09 | 23 |
| epithelial tube | 2.00e-08 | 47 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.142214 |
| MA0004.1 | 0.6888 |
| MA0006.1 | 0.497533 |
| MA0007.1 | 0.672186 |
| MA0009.1 | 1.15569 |
| MA0014.1 | 0.0809287 |
| MA0017.1 | 1.30949 |
| MA0019.1 | 0.964875 |
| MA0024.1 | 1.11019 |
| MA0025.1 | 3.08637 |
| MA0027.1 | 2.81824 |
| MA0028.1 | 0.509589 |
| MA0029.1 | 1.08753 |
| MA0030.1 | 1.09438 |
| MA0031.1 | 1.05719 |
| MA0038.1 | 0.846479 |
| MA0040.1 | 1.16866 |
| MA0041.1 | 0.604221 |
| MA0042.1 | 0.589368 |
| MA0043.1 | 1.25564 |
| MA0046.1 | 1.1929 |
| MA0048.1 | 0.735223 |
| MA0050.1 | 0.731539 |
| MA0051.1 | 0.856094 |
| MA0052.1 | 1.17701 |
| MA0055.1 | 0.125758 |
| MA0056.1 | 0 |
| MA0057.1 | 0.701847 |
| MA0058.1 | 0.581673 |
| MA0059.1 | 0.59559 |
| MA0060.1 | 0.403071 |
| MA0061.1 | 0.438628 |
| MA0063.1 | 0 |
| MA0066.1 | 0.834648 |
| MA0067.1 | 1.50873 |
| MA0068.1 | 0.713436 |
| MA0069.1 | 1.17737 |
| MA0070.1 | 1.16732 |
| MA0071.1 | 0.73062 |
| MA0072.1 | 1.15853 |
| MA0073.1 | 0.0471131 |
| MA0074.1 | 0.795862 |
| MA0076.1 | 1.35592 |
| MA0077.1 | 1.13603 |
| MA0078.1 | 0.891476 |
| MA0081.1 | 0.621611 |
| MA0083.1 | 1.25482 |
| MA0084.1 | 1.84013 |
| MA0087.1 | 1.21037 |
| MA0088.1 | 0.201215 |
| MA0089.1 | 0 |
| MA0090.1 | 0.650768 |
| MA0091.1 | 1.67688 |
| MA0092.1 | 0.651119 |
| MA0093.1 | 0.519148 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.783305 |
| MA0101.1 | 0.605676 |
| MA0103.1 | 0.540576 |
| MA0105.1 | 0.313353 |
| MA0106.1 | 0.899777 |
| MA0107.1 | 0.533522 |
| MA0108.2 | 0.989014 |
| MA0109.1 | 0 |
| MA0111.1 | 0.666525 |
| MA0113.1 | 3.3407 |
| MA0114.1 | 1.11164 |
| MA0115.1 | 2.80994 |
| MA0116.1 | 0.497293 |
| MA0117.1 | 1.22527 |
| MA0119.1 | 0.606338 |
| MA0122.1 | 1.24573 |
| MA0124.1 | 1.45461 |
| MA0125.1 | 1.37907 |
| MA0130.1 | 0 |
| MA0131.1 | 0.960068 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.29308 |
| MA0136.1 | 0.817395 |
| MA0139.1 | 0.365453 |
| MA0140.1 | 0.78318 |
| MA0141.1 | 0.563066 |
| MA0142.1 | 1.04199 |
| MA0143.1 | 0.887119 |
| MA0144.1 | 1.11951 |
| MA0145.1 | 0.21199 |
| MA0146.1 | 0.0944145 |
| MA0147.1 | 0.453952 |
| MA0148.1 | 0.706718 |
| MA0149.1 | 0.611881 |
| MA0062.2 | 0.319836 |
| MA0035.2 | 0.788288 |
| MA0039.2 | 0.238019 |
| MA0138.2 | 0.951653 |
| MA0002.2 | 0.368961 |
| MA0137.2 | 0.559766 |
| MA0104.2 | 0.386166 |
| MA0047.2 | 0.845655 |
| MA0112.2 | 0.211985 |
| MA0065.2 | 1.14711 |
| MA0150.1 | 0.67206 |
| MA0151.1 | 0 |
| MA0152.1 | 0.84577 |
| MA0153.1 | 1.31015 |
| MA0154.1 | 0.263609 |
| MA0155.1 | 0.230016 |
| MA0156.1 | 1.35382 |
| MA0157.1 | 1.0083 |
| MA0158.1 | 0 |
| MA0159.1 | 0.465802 |
| MA0160.1 | 0.71003 |
| MA0161.1 | 0 |
| MA0162.1 | 0.346529 |
| MA0163.1 | 0.0996272 |
| MA0164.1 | 0.817786 |
| MA0080.2 | 0.534538 |
| MA0018.2 | 0.828253 |
| MA0099.2 | 0.944966 |
| MA0079.2 | 0.0234849 |
| MA0102.2 | 1.8929 |
| MA0258.1 | 0.419871 |
| MA0259.1 | 0.441366 |
| MA0442.1 | 0 |
