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MCL coexpression mm9:416

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Phase1 CAGE Peaks

  Short description
Mm9::chr10:5734717..5734727,- p12@Esr1
Mm9::chr10:75399907..75399919,+ +
p@chr10:75399907..75399919
Mm9::chr12:16596549..16596632,- p1@Lpin1
Mm9::chr12:72977020..72977051,+ p@chr12:72977020..72977051
+
Mm9::chr15:76137124..76137135,- p@chr15:76137124..76137135
-
Mm9::chr18:64639050..64639061,- p@chr18:64639050..64639061
-
Mm9::chr3:129234914..129234917,- p@chr3:129234914..129234917
-
Mm9::chr4:147976089..147976106,+ p@chr4:147976089..147976106
+
Mm9::chr5:125976345..125976366,+ p@chr5:125976345..125976366
+
Mm9::chr5:66473042..66473055,- p@chr5:66473042..66473055
-
Mm9::chr6:142421318..142421325,- p8@Gys2
Mm9::chr6:142421333..142421360,- p5@Gys2
Mm9::chr6:142421364..142421402,- p2@Gys2
Mm9::chr6:142421417..142421436,- p4@Gys2
Mm9::chr6:142421480..142421505,- p3@Gys2
Mm9::chr7:148021087..148021088,+ p7@1190003J15Rik
Mm9::chr8:113560785..113560799,+ p@chr8:113560785..113560799
+
Mm9::chr9:106150191..106150205,- p1@Alas1


Enriched pathways on this co-expression clusterSummary:
Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.
Analyst: Emmanuel Dimont

link to source dataset
data


GO IDGO nameFDR corrected p-value
GO:0031529ruffle organization and biogenesis0.0124236528193307
GO:0019842vitamin binding0.0124236528193307
GO:0032868response to insulin stimulus0.0124236528193307
GO:0043434response to peptide hormone stimulus0.0124236528193307
GO:0032870cellular response to hormone stimulus0.0124236528193307
GO:0045839negative regulation of mitosis0.0124236528193307
GO:0016749N-succinyltransferase activity0.0124236528193307
GO:0004373glycogen (starch) synthase activity0.0124236528193307
GO:0032869cellular response to insulin stimulus0.0124236528193307
GO:00038705-aminolevulinate synthase activity0.0124236528193307
GO:0031532actin cytoskeleton reorganization0.0133092333762021
GO:0016748succinyltransferase activity0.0133092333762021
GO:0004813alanine-tRNA ligase activity0.0133092333762021
GO:0006419alanyl-tRNA aminoacylation0.0133092333762021
GO:0006590thyroid hormone generation0.0206975809343111
GO:0035251UDP-glucosyltransferase activity0.0219120840674093
GO:0008195phosphatidate phosphatase activity0.0219120840674093
GO:0046527glucosyltransferase activity0.0241405635418043
GO:0019841retinol binding0.0248268930780587
GO:0045598regulation of fat cell differentiation0.0248268930780587
GO:0042403thyroid hormone metabolic process0.0260103751302593
GO:0016918retinal binding0.0260103751302593
GO:0006519amino acid and derivative metabolic process0.0260103751302593
GO:0009250glucan biosynthetic process0.0260103751302593
GO:0005978glycogen biosynthetic process0.0260103751302593
GO:0006783heme biosynthetic process0.0260103751302593
GO:0009058biosynthetic process0.0260103751302593
GO:0033014tetrapyrrole biosynthetic process0.0260103751302593
GO:0006779porphyrin biosynthetic process0.0260103751302593
GO:0005501retinoid binding0.0260103751302593
GO:0019840isoprenoid binding0.0260103751302593
GO:0009308amine metabolic process0.0271903979283695
GO:0009725response to hormone stimulus0.0286942308675125
GO:0042168heme metabolic process0.0286942308675125
GO:0006807nitrogen compound metabolic process0.0286942308675125
GO:0033692cellular polysaccharide biosynthetic process0.0293600272437102
GO:0033013tetrapyrrole metabolic process0.0293600272437102
GO:0006778porphyrin metabolic process0.0293600272437102
GO:0000271polysaccharide biosynthetic process0.0301923598486603
GO:0051716cellular response to stimulus0.0309826520203106
GO:0045444fat cell differentiation0.0347467450100203
GO:0046148pigment biosynthetic process0.0373293804433897
GO:0007088regulation of mitosis0.0373293804433897
GO:0000902cell morphogenesis0.0373293804433897
GO:0032989cellular structure morphogenesis0.0373293804433897
GO:0006073glucan metabolic process0.0399590170377478
GO:0005977glycogen metabolic process0.0399590170377478
GO:0042440pigment metabolic process0.0399590170377478
GO:0016769transferase activity, transferring nitrogenous groups0.0432867010868868
GO:0006112energy reserve metabolic process0.0432867010868868
GO:0019748secondary metabolic process0.0480042215885874
GO:0006418tRNA aminoacylation for protein translation0.0480042215885874
GO:0043038amino acid activation0.0480042215885874
GO:0043039tRNA aminoacylation0.0480042215885874
GO:0030170pyridoxal phosphate binding0.0480042215885874
GO:0005976polysaccharide metabolic process0.0480042215885874
GO:0005496steroid binding0.0480042215885874
GO:0003707steroid hormone receptor activity0.0480042215885874
GO:0044264cellular polysaccharide metabolic process0.0480042215885874
GO:0004879ligand-dependent nuclear receptor activity0.0480042215885874
GO:0016876ligase activity, forming aminoacyl-tRNA and related compounds0.0480042215885874
GO:0016875ligase activity, forming carbon-oxygen bonds0.0480042215885874
GO:0004812aminoacyl-tRNA ligase activity0.0480042215885874
GO:0009059macromolecule biosynthetic process0.0495027323876971



Relative expression of the co-expression cluster over median
Analyst:





Enriched sample ontology terms on this co-expression clusterSummary:To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. Analyst: Hideya Kawaji

links to source dataset

cell_data
uberon_data


Cell Type
Ontology termp-valuen
metabolising cell1.72e-075
endopolyploid cell1.72e-075
parenchymal cell1.72e-075
polyploid cell1.72e-075
hepatocyte1.72e-075

Uber Anatomy
Ontology termp-valuen
exocrine gland1.99e-2825
exocrine system1.99e-2825
liver4.08e-2722
epithelial sac4.08e-2722
digestive gland4.08e-2722
epithelium of foregut-midgut junction4.08e-2722
anatomical boundary4.08e-2722
hepatobiliary system4.08e-2722
foregut-midgut junction4.08e-2722
hepatic diverticulum4.08e-2722
liver primordium4.08e-2722
septum transversum4.08e-2722
liver bud4.08e-2722
digestive tract diverticulum1.04e-2523
sac1.04e-2523
abdomen element8.34e-1849
abdominal segment element8.34e-1849
abdominal segment of trunk8.34e-1849
abdomen8.34e-1849
trunk mesenchyme5.57e-1545
mesenchyme5.02e-1361
entire embryonic mesenchyme5.02e-1361
epithelial tube7.89e-1347
subdivision of trunk1.47e-1166
gland1.22e-1065
endocrine gland7.89e-1060
trunk region element1.22e-0879
gut epithelium6.78e-0855
endocrine system2.66e-0772
trunk7.36e-0790


TFBS overrepresentationSummary:The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. Analyst: Michiel de Hoon

link to source data
Novel motifs
data

Jaspar motifs
data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.02809
MA0004.10.559722
MA0006.10.289293
MA0007.10.181021
MA0009.10.5557
MA0014.10.165342
MA0017.11.64429
MA0019.10.394308
MA0024.10.516087
MA0025.11.82115
MA0027.12.16618
MA0028.10.0910441
MA0029.11.24219
MA0030.10.502474
MA0031.11.18689
MA0038.10.301835
MA0040.10.567108
MA0041.10.854076
MA0042.10.131965
MA0043.10.644695
MA0046.11.43706
MA0048.11.1804
MA0050.10.219748
MA0051.10.309072
MA0052.10.574473
MA0055.10.368697
MA0056.10
MA0057.10.297183
MA0058.10.401421
MA0059.10.13543
MA0060.10.0476793
MA0061.10.218812
MA0063.10
MA0066.10.293002
MA0067.10.879099
MA0068.10.524433
MA0069.10.574784
MA0070.10.565924
MA0071.10.625332
MA0072.10.558195
MA0073.10.661981
MA0074.10.731206
MA0076.10.110983
MA0077.10.538513
MA0078.10.336143
MA0081.10.150322
MA0083.10.643958
MA0084.11.1979
MA0087.10.604077
MA0088.10.0282169
MA0089.10
MA0090.10.167748
MA0091.10.582275
MA0092.10.167962
MA0093.11.08707
MA0095.10
MA0098.10
MA0100.10.255651
MA0101.10.141127
MA0103.10.106139
MA0105.10.0222933
MA0106.10.342589
MA0107.10.335745
MA0108.20.413973
MA0109.10
MA0111.10.177475
MA0113.10.319332
MA0114.13.5401
MA0115.12.6399
MA0116.10.288992
MA0117.11.49766
MA0119.11.386
MA0122.10.635764
MA0124.10.828115
MA0125.10.757653
MA0130.10
MA0131.10.390422
MA0132.10
MA0133.10
MA0135.10.67864
MA0136.10.280269
MA0139.10.94327
MA0140.10.255562
MA0141.11.23603
MA0142.10.457961
MA0143.10.885347
MA0144.10.0609575
MA0145.10.847843
MA0146.10.129919
MA0147.10.0666796
MA0148.10.587598
MA0149.10.144679
MA0062.20.0237736
MA0035.20.259203
MA0039.20.0352926
MA0138.20.383644
MA0002.20.338271
MA0137.20.371067
MA0104.20.371038
MA0047.20.301217
MA0112.20.584689
MA0065.20.372253
MA0150.12.30318
MA0151.10
MA0152.10.301303
MA0153.10.694211
MA0154.10.162966
MA0155.10.0417374
MA0156.10.110475
MA0157.10.429861
MA0158.10
MA0159.10.534512
MA0160.13.28074
MA0161.10
MA0162.10.00359771
MA0163.10.14522
MA0164.10.280556
MA0080.20.103116
MA0018.21.43115
MA0099.20.986085
MA0079.20.0252744
MA0102.21.24942
MA0258.10.197969
MA0259.10.221921
MA0442.10