UBERON:0007100
From FANTOM5_SSTAR
| Name: | primary circulatory organ | ||
|---|---|---|---|
| Namespace: | FANTOM | ||
| Definition: | "A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood[GO]." [GO:0007507] | ||
| Xrefs: |
| ||
| Synonyms: |
"adult heart" RELATED [FBbt:00003154] "cardiac pump" EXACT [] "cardiac structure" RELATED [] "dorsal tube" NARROW [Wikipedia:Heart] "heart" NARROW [GO:0007507] "heart or heart like organ" EXACT [] | ||
| Comments: | editor note: we need to find the appropriate GO process to use for the definition - 'blood circulation' may not apply to invertebrates; 'circulatory system process' is circular. Note we cannot use a part_of-based definition as this results in the iris and all vascular elements being categorized as circulatory organs. Taxon notes: note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. "The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian". Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis. Gene notes: Bmp, Nkx, Gata | ||
| Subset: | grouping_class |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0015228(circulatory organ) |
|---|---|
| part_of: | UBERON:0001009(circulatory system) |
Children
| is a: | UBERON:0000948 (heart) |
|---|---|
| part of: | CL:0000746 (cardiac muscle cell),CL:0002494 (cardiocyte) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10016-101C7 (heart, adult, pool1)
- 10046-101G1 (heart, fetal, pool1)
- 10050-101G5 (heart, adult, diseased post-infarction, donor1)
- 10051-101G6 (heart, adult, diseased, donor1)
- 10078-102A6 (left ventricle, adult, donor1)
- 10079-102A7 (left atrium, adult, donor1)
- 10087-102B6
- 10205-103F7 (heart - mitral valve, adult)
- 10206-103F8 (heart - pulmonic valve, adult)
- 10207-103F9 (heart - tricuspid valve, adult)
... further results Mouse (Mus musculus)
- 10016-101C7 (heart, adult, pool1)
- 10046-101G1 (heart, fetal, pool1)
- 10050-101G5 (heart, adult, diseased post-infarction, donor1)
- 10051-101G6 (heart, adult, diseased, donor1)
- 10078-102A6 (left ventricle, adult, donor1)
- 10079-102A7 (left atrium, adult, donor1)
- 10087-102B6
- 10205-103F7 (heart - mitral valve, adult)
- 10206-103F8 (heart - pulmonic valve, adult)
- 10207-103F9 (heart - tricuspid valve, adult)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0007100 (primary circulatory organ), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 1.09e-81 | FFCP PHASE1:Mm9::chr1:137747392..137747402,-#_51964097263442c9eecfc750d638af3e | p@chr1:137747392..137747402, - |
| 1.09e-81 | FFCP PHASE1:Mm9::chr4:147375434..147375447,+#_51964097263442c9eecfc750d638af3e | p@chr4:147375434..147375447, + |
| 1.09e-81 | FFCP PHASE2:Mm9::chr4:147375434..147375447,+#_51964097263442c9eecfc750d638af3e | p@chr4:147375434..147375447, + |
| 1.09e-81 | FFCP PHASE1:Mm9::chr9:24549775..24549776,-#_51964097263442c9eecfc750d638af3e | p@chr9:24549775..24549776, - |
| 1.09e-81 | FFCP PHASE2:Mm9::chr1:137747392..137747402,-#_51964097263442c9eecfc750d638af3e | p@chr1:137747392..137747402, - |
| 1.09e-81 | FFCP PHASE2:Mm9::chr9:24549775..24549776,-#_51964097263442c9eecfc750d638af3e | p@chr9:24549775..24549776, - |
| 5.69e-81 | FFCP PHASE2:Hg19::chr17:77019002..77019027,+#_653e72ab25b5d33370f1abf2903c44fd | p@chr17:77019002..77019027, + |
| 5.69e-81 | FFCP PHASE1:Hg19::chr17:77019002..77019027,+#_653e72ab25b5d33370f1abf2903c44fd | p@chr17:77019002..77019027, + |
| 2.21e-79 | FFCP PHASE1:Hg19::chr17:77018953..77018966,+#_10881b560d1ebe029bb42fde521acc61 | p@chr17:77018953..77018966, + |
| 2.21e-79 | FFCP PHASE2:Hg19::chr17:77018953..77018966,+#_10881b560d1ebe029bb42fde521acc61 | p@chr17:77018953..77018966, + |
| 1.88e-78 | FFCP PHASE1:Mm9::chr4:140980456..140980463,+#_a6e8a2c1f45de514e93b752b8ba5f4ec | p@chr4:140980456..140980463, + |
| 1.88e-78 | FFCP PHASE2:Mm9::chr4:140980456..140980463,+#_a6e8a2c1f45de514e93b752b8ba5f4ec | p@chr4:140980456..140980463, + |
| 1.92e-77 | FFCP PHASE2:Mm9::chr12:113728951..113728965,+#_77d4c4d9af3217b9c97dce7da1dc578c | p@chr12:113728951..113728965, + |
| 1.92e-77 | FFCP PHASE2:Mm9::chr1:137737483..137737497,-#_77d4c4d9af3217b9c97dce7da1dc578c | p@chr1:137737483..137737497, - |
| 1.92e-77 | FFCP PHASE1:Mm9::chr12:113728951..113728965,+#_77d4c4d9af3217b9c97dce7da1dc578c | p@chr12:113728951..113728965, + |
| 1.92e-77 | FFCP PHASE1:Mm9::chr1:137737483..137737497,-#_77d4c4d9af3217b9c97dce7da1dc578c | p@chr1:137737483..137737497, - |
| 2.14e-77 | FFCP PHASE1:Mm9::chr19:36187511..36187515,-#_8b0f994f15e8a19d643bd690f0d14ce7 | p@chr19:36187511..36187515, - |
| 2.14e-77 | FFCP PHASE2:Mm9::chr19:36187511..36187515,-#_8b0f994f15e8a19d643bd690f0d14ce7 | p@chr19:36187511..36187515, - |
| 2.14e-77 | FFCP PHASE2:Mm9::chr4:147375200..147375220,+#_8b0f994f15e8a19d643bd690f0d14ce7 | p@chr4:147375200..147375220, + |
| 2.14e-77 | FFCP PHASE1:Mm9::chr4:147375200..147375220,+#_8b0f994f15e8a19d643bd690f0d14ce7 | p@chr4:147375200..147375220, + |
| 8.14e-77 | FFCP PHASE1:Mm9::chr4:147375901..147375913,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr4:147375901..147375913, + |
| 8.14e-77 | FFCP PHASE1:Mm9::chr5:120286706..120286736,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr5:120286706..120286736, + |
| 8.14e-77 | FFCP PHASE2:Mm9::chr19:36193772..36193793,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr19:36193772..36193793, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55563577..55563611,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55563577..55563611, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55565785..55565833,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55565785..55565833, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55568737..55568746,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55568737..55568746, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55568790..55568803,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55568790..55568803, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55568937..55568988,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55568937..55568988, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55571909..55571953,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55571909..55571953, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55572120..55572173,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55572120..55572173, + |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55579265..55579297,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55579265..55579297, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55581579..55581620,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55581579..55581620, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55584197..55584239,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55584197..55584239, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55584272..55584298,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55584272..55584298, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55584663..55584731,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55584663..55584731, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr14:55586837..55586880,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55586837..55586880, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr1:137743272..137743307,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137743272..137743307, + |
| 8.14e-77 | FFCP PHASE2:Mm9::chr1:137744333..137744352,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137744333..137744352, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr1:137744550..137744565,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137744550..137744565, + |
| 8.14e-77 | FFCP PHASE2:Mm9::chr1:137744611..137744621,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137744611..137744621, + |
| 8.14e-77 | FFCP PHASE2:Mm9::chr1:137744636..137744654,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137744636..137744654, + |
| 8.14e-77 | FFCP PHASE2:Mm9::chr1:137744668..137744681,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137744668..137744681, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr1:137745434..137745445,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137745434..137745445, + |
| 8.14e-77 | FFCP PHASE2:Mm9::chr1:137747289..137747313,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137747289..137747313, + |
| 8.14e-77 | FFCP PHASE2:Mm9::chr1:137747382..137747385,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137747382..137747385, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr1:137747953..137747967,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137747953..137747967, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr11:58815923..58815951,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr11:58815923..58815951, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr11:65461897..65461929,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr11:65461897..65461929, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr5:120286706..120286736,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr5:120286706..120286736, + |
| 8.14e-77 | FFCP PHASE2:Mm9::chr11:58815923..58815951,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr11:58815923..58815951, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr11:65461897..65461929,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr11:65461897..65461929, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55563577..55563611,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55563577..55563611, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55565785..55565833,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55565785..55565833, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55568737..55568746,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55568737..55568746, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55568790..55568803,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55568790..55568803, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55568937..55568988,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55568937..55568988, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55571909..55571953,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55571909..55571953, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55572120..55572173,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55572120..55572173, + |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55579265..55579297,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55579265..55579297, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55581579..55581620,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55581579..55581620, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55584197..55584239,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55584197..55584239, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55584272..55584298,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55584272..55584298, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55584663..55584731,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55584663..55584731, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr14:55586837..55586880,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr14:55586837..55586880, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr15:88850827..88850850,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p2@Mov10l1 |
| 8.14e-77 | FFCP PHASE1:Mm9::chr19:36193772..36193793,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr19:36193772..36193793, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr1:137743272..137743307,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137743272..137743307, + |
| 8.14e-77 | FFCP PHASE1:Mm9::chr1:137744333..137744352,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137744333..137744352, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr1:137744550..137744565,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137744550..137744565, + |
| 8.14e-77 | FFCP PHASE1:Mm9::chr1:137744611..137744621,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137744611..137744621, + |
| 8.14e-77 | FFCP PHASE1:Mm9::chr1:137744636..137744654,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137744636..137744654, + |
| 8.14e-77 | FFCP PHASE1:Mm9::chr1:137744668..137744681,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137744668..137744681, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr1:137745434..137745445,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137745434..137745445, + |
| 8.14e-77 | FFCP PHASE1:Mm9::chr1:137747289..137747313,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137747289..137747313, + |
| 8.14e-77 | FFCP PHASE1:Mm9::chr1:137747382..137747385,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137747382..137747385, - |
| 8.14e-77 | FFCP PHASE1:Mm9::chr1:137747953..137747967,-#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr1:137747953..137747967, - |
| 8.14e-77 | FFCP PHASE2:Mm9::chr4:147375901..147375913,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p@chr4:147375901..147375913, + |
| 8.14e-77 | FFCP PHASE2:Mm9::chr15:88850827..88850850,+#_0ebbd06366a73ebcea0f8bc6cb089866 | p2@Mov10l1 |
| 1.2e-73 | FFCP PHASE2:Mm9::chr1:137742152..137742184,-#_fe40d489e19641fa791cef9be436ab32 | p@chr1:137742152..137742184, - |
| 1.2e-73 | FFCP PHASE1:Mm9::chr1:137742152..137742184,-#_fe40d489e19641fa791cef9be436ab32 | p@chr1:137742152..137742184, - |
| 1.46e-72 | FFCP PHASE1:Mm9::chr14:55577329..55577367,-#_465d556be13caa16245407d1aa2d5e38 | p@chr14:55577329..55577367, - |
| 1.46e-72 | FFCP PHASE1:Mm9::chr16:5431481..5431510,+#_465d556be13caa16245407d1aa2d5e38 | p@chr16:5431481..5431510, + |
| 1.46e-72 | FFCP PHASE1:Mm9::chr1:137742470..137742481,+#_465d556be13caa16245407d1aa2d5e38 | p@chr1:137742470..137742481, + |
| 1.46e-72 | FFCP PHASE2:Mm9::chr7:4473478..4473505,-#_465d556be13caa16245407d1aa2d5e38 | p2@Tnni3 |
| 1.46e-72 | FFCP PHASE1:Mm9::chr7:4473478..4473505,-#_465d556be13caa16245407d1aa2d5e38 | p2@Tnni3 |
| 1.46e-72 | FFCP PHASE2:Mm9::chr16:5431481..5431510,+#_465d556be13caa16245407d1aa2d5e38 | p@chr16:5431481..5431510, + |
| 1.46e-72 | FFCP PHASE2:Mm9::chr14:55577329..55577367,-#_465d556be13caa16245407d1aa2d5e38 | p@chr14:55577329..55577367, - |
| 1.46e-72 | FFCP PHASE2:Mm9::chr1:137742470..137742481,+#_465d556be13caa16245407d1aa2d5e38 | p@chr1:137742470..137742481, + |
| 1.63e-72 | FFCP PHASE2:Mm9::chr19:36193739..36193752,-#_60735c988619e5db959bc6655406d1ec | p@chr19:36193739..36193752, - |
| 1.63e-72 | FFCP PHASE2:Mm9::chr10:53062244..53062249,+#_60735c988619e5db959bc6655406d1ec | p@chr10:53062244..53062249, + |
| 1.63e-72 | FFCP PHASE2:Mm9::chr5:58108164..58108178,+#_60735c988619e5db959bc6655406d1ec | p@chr5:58108164..58108178, + |
| 1.63e-72 | FFCP PHASE2:Mm9::chr2:17382210..17382221,-#_60735c988619e5db959bc6655406d1ec | p5@Nebl |
| 1.63e-72 | FFCP PHASE1:Mm9::chr16:38713504..38713520,-#_60735c988619e5db959bc6655406d1ec | p11@Arhgap31 |
| 1.63e-72 | FFCP PHASE1:Mm9::chr19:36193739..36193752,-#_60735c988619e5db959bc6655406d1ec | p@chr19:36193739..36193752, - |
| 1.63e-72 | FFCP PHASE1:Mm9::chr2:113880065..113880076,+#_60735c988619e5db959bc6655406d1ec | p1@ENSMUST00000154140 |
| 1.63e-72 | FFCP PHASE1:Mm9::chr2:17382210..17382221,-#_60735c988619e5db959bc6655406d1ec | p5@Nebl |
| 1.63e-72 | FFCP PHASE2:Mm9::chr2:113880065..113880076,+#_60735c988619e5db959bc6655406d1ec | p1@ENSMUST00000154140 |
| 1.63e-72 | FFCP PHASE2:Mm9::chr16:38713504..38713520,-#_60735c988619e5db959bc6655406d1ec | p11@Arhgap31 |
| 1.63e-72 | FFCP PHASE1:Mm9::chr10:53062244..53062249,+#_60735c988619e5db959bc6655406d1ec | p@chr10:53062244..53062249, + |
| 1.63e-72 | FFCP PHASE1:Mm9::chr5:58108164..58108178,+#_60735c988619e5db959bc6655406d1ec | p@chr5:58108164..58108178, + |
