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Revision as of 17:10, 15 June 2012

Name:digestive system
Definition:"Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." [FB:gg, NLM:alimentary+system, Wikipedia:Digestive_system]
Xrefs:
links:

AAO:0000129
BILA:0000082
BTO:0000058
EFO:0000793
EV:0100056
FBbt:00005055
FMA:7152
GAID:278
galen:DigestiveSystem
MA:0002431
MAT:0000018
MESH:A.03
MIAA:0000018
ncithesaurus:Digestive_System
SCTID:278859004
TADS:0000170
TAO:0000339
WBbt:0005748
XAO:0000125

ZFA:0000339
Synonyms: "alimentary system" RELATED []
"alimentary tract" RELATED []
"gastrointestinal system" RELATED []
"gut" RELATED []
Comments:note that many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class
Alt_id: UBERON:FBbt_00005055-FMA_7152-MA_0000323-MIAA_0000018-WBbt_0005748-XAO_0000125-ZFA_0000339
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0000467(anatomical system)
disjoint_from:UBERON:0001008(renal system),UBERON:0001009(circulatory system),UBERON:0001016(nervous system),UBERON:0001033(gustatory system),UBERON:0001434(skeletal system),UBERON:0002204(musculoskeletal system),UBERON:0002294(biliary system),UBERON:0002330(exocrine system),UBERON:0002390(hematopoietic system),UBERON:0002405(immune system),UBERON:0002416(integumental system),UBERON:0002423(hepatobiliary system),UBERON:0004456(entire sense organ system)



Children

is a:FF:10628-108H7 ()
disjoint from:UBERON:0000949 (endocrine system),UBERON:0000990 (reproductive system),UBERON:0001004 (respiratory system)
part of:UBERON:0001555 (digestive tract),UBERON:0002106 (spleen),UBERON:0002107 (liver),UBERON:0002423 (hepatobiliary system),UBERON:0003928 (digestive system duct),UBERON:0005409 (gastrointestinal system),UBERON:0006925 (digestive gland),UBERON:0013765 (digestive system element)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001007 (digestive system), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
4.99e-36FFCP PHASE1:Hg19::chr14:38064429..38064486,-#_0616d1223300b67f4b8762a3d5b094e5p1@FOXA1
4.99e-36FFCP PHASE2:Hg19::chr14:38064429..38064486,-#_0616d1223300b67f4b8762a3d5b094e5p1@FOXA1
1.61e-35FFCP PHASE2:Hg19::chr5:134369879..134369898,-#_1e8e7145e21f4c8192a0568e5a5e36a3p2@PITX1
1.61e-35FFCP PHASE1:Hg19::chr5:134369879..134369898,-#_1e8e7145e21f4c8192a0568e5a5e36a3p2@PITX1
1.29e-32FFCP PHASE2:Hg19::chr16:68269971..68270059,-#_c3e61fb805f74f7f2d0743cd8e4cd9f9p1@ESRP2
1.29e-32FFCP PHASE1:Hg19::chr16:68269971..68270059,-#_c3e61fb805f74f7f2d0743cd8e4cd9f9p1@ESRP2
4.79e-32FFCP PHASE1:Hg19::chr16:86542652..86542692,-#_eff3c5ce214ef9889a10196575e4780ep2@LOC400550
4.79e-32FFCP PHASE2:Hg19::chr16:86542652..86542692,-#_eff3c5ce214ef9889a10196575e4780ep2@LOC400550
9.87e-31FFCP PHASE1:Hg19::chr16:86532148..86532166,-#_e8fbc2ee8528f078ea6751a385336e0ep@chr16:86532148..86532166, -
9.87e-31FFCP PHASE2:Hg19::chr16:86532148..86532166,-#_e8fbc2ee8528f078ea6751a385336e0ep@chr16:86532148..86532166, -
1.01e-30FFCP PHASE1:Hg19::chr18:47721315..47721430,-#_50a680a814354974defddb05c7d0ed36p1@MYO5B
1.01e-30FFCP PHASE2:Hg19::chr18:47721315..47721430,-#_50a680a814354974defddb05c7d0ed36p1@MYO5B
1.18e-30FFCP PHASE2:Hg19::chr14:65409452..65409479,-#_7da0b1c6845b74230b1e1466b3ccece7p1@GPX2
1.18e-30FFCP PHASE1:Hg19::chr14:65409452..65409479,-#_7da0b1c6845b74230b1e1466b3ccece7p1@GPX2
5.14e-30FFCP PHASE1:Mm9::chr12:58646974..58647003,-#_b422ad199b5ed8c70d33ae6969e87da8p1@Foxa1
5.14e-30FFCP PHASE2:Mm9::chr12:58646974..58647003,-#_b422ad199b5ed8c70d33ae6969e87da8p1@Foxa1
5.76e-30FFCP PHASE1:Mm9::chr13:4190454..4190472,+#_08d0a01aae7838367a0453314279bdf0p2@Akr1c13
5.76e-30FFCP PHASE2:Mm9::chr13:4190454..4190472,+#_08d0a01aae7838367a0453314279bdf0p2@Akr1c13
1.52e-29FFCP PHASE2:Hg19::chr20:62168672..62168713,-#_b1bcb8a0b817d8c3d25eede4e92ebbfep1@PTK6
1.52e-29FFCP PHASE1:Hg19::chr20:62168672..62168713,-#_b1bcb8a0b817d8c3d25eede4e92ebbfep1@PTK6
4.1e-29FFCP PHASE1:Hg19::chr16:68260798..68260800,-#_a3433454107512d40462fef5c2fd8f41p@chr16:68260798..68260800, -
4.1e-29FFCP PHASE2:Hg19::chr16:68260798..68260800,-#_a3433454107512d40462fef5c2fd8f41p@chr16:68260798..68260800, -
6.23e-29FFCP PHASE2:Hg19::chr1:201979743..201979762,+#_51fa1043593ba12a06a3dc7241a50f9bp1@ELF3
6.23e-29FFCP PHASE1:Hg19::chr1:201979743..201979762,+#_51fa1043593ba12a06a3dc7241a50f9bp1@ELF3
7.64e-29FFCP PHASE1:Mm9::chr2:180976725..180976753,-#_0b35c27c892efb7dcb39c4899516e943p2@BC006779
7.64e-29FFCP PHASE2:Mm9::chr2:180976725..180976753,-#_0b35c27c892efb7dcb39c4899516e943p2@BC006779
1.66e-28FFCP PHASE1:Hg19::chr19:42212526..42212575,+#_4367a173f187e020acded12f5e6e7294p1@CEACAM5
1.66e-28FFCP PHASE2:Hg19::chr19:42212526..42212575,+#_4367a173f187e020acded12f5e6e7294p1@CEACAM5
2.87e-28FFCP PHASE2:Hg19::chr17:7164410..7164457,-#_78ff80e629ce72c3b17c0deb9becbb5ap3@CLDN7
2.87e-28FFCP PHASE1:Hg19::chr17:7164410..7164457,-#_78ff80e629ce72c3b17c0deb9becbb5ap3@CLDN7
7.57e-28FFCP PHASE1:Mm9::chr8:70018742..70018782,+#_05299ad582dd90b6ef3deacd0ff976bep1@Nat2
7.57e-28FFCP PHASE2:Mm9::chr8:70018742..70018782,+#_05299ad582dd90b6ef3deacd0ff976bep1@Nat2
1.1e-27FFCP PHASE1:Hg19::chr5:134369905..134369972,-#_00466d6f24c273e721176e72354c6ee4p1@PITX1
1.1e-27FFCP PHASE2:Hg19::chr5:134369905..134369972,-#_00466d6f24c273e721176e72354c6ee4p1@PITX1
1.82e-27FFCP PHASE2:Mm9::chr5:65194752..65194769,+#_1b1c229f140a0bf8dcd6dd14267ba41ap1@Klf3
1.82e-27FFCP PHASE1:Mm9::chr5:65194752..65194769,+#_1b1c229f140a0bf8dcd6dd14267ba41ap1@Klf3
3.7e-27FFCP PHASE1:Mm9::chr2:51828449..51828501,-#_2c0e26923913a90813d349ed1f162f09p1@Nmi
3.7e-27FFCP PHASE2:Mm9::chr2:51828449..51828501,-#_2c0e26923913a90813d349ed1f162f09p1@Nmi
3.88e-27FFCP PHASE1:Hg19::chr6:1312325..1312340,+#_5e72491047b9e78d9682dd802f95db25p1@FOXQ1
3.88e-27FFCP PHASE2:Hg19::chr6:1312325..1312340,+#_5e72491047b9e78d9682dd802f95db25p1@FOXQ1
5.02e-27FFCP PHASE2:Hg19::chr1:26503974..26504025,+#_12e54e4eb849768cef3d3c8be7c30b35p1@CNKSR1
5.02e-27FFCP PHASE1:Hg19::chr1:26503974..26504025,+#_12e54e4eb849768cef3d3c8be7c30b35p1@CNKSR1
5.37e-27FFCP PHASE1:Mm9::chr1:37722539..37722560,-#_55faa335ba2119deb1f0f244be53e83bp@chr1:37722539..37722560, -
5.37e-27FFCP PHASE2:Mm9::chr1:37722539..37722560,-#_55faa335ba2119deb1f0f244be53e83bp@chr1:37722539..37722560, -
5.43e-27FFCP PHASE2:Hg19::chr11:394196..394258,+#_63ed13bbf7f985e7aed18e7d69a3620dp1@PKP3
5.43e-27FFCP PHASE1:Hg19::chr11:394196..394258,+#_63ed13bbf7f985e7aed18e7d69a3620dp1@PKP3
6.53e-27FFCP PHASE2:Mm9::chr13:4278636..4278655,-#_c013150f06ea29c3b98f73d39b1f985dp1@Akr1c12
6.53e-27FFCP PHASE1:Mm9::chr13:4278636..4278655,-#_c013150f06ea29c3b98f73d39b1f985dp1@Akr1c12
1.11e-26FFCP PHASE2:Mm9::chr1:58852306..58852403,+#_715fd390d9524790b57e8556f2711cd4p2@Casp8
1.11e-26FFCP PHASE1:Mm9::chr1:58852306..58852403,+#_715fd390d9524790b57e8556f2711cd4p2@Casp8
2.45e-26FFCP PHASE2:Mm9::chr6:7795251..7795299,+#_21f3545ac2f299551108819ae1f63727p1@C1galt1
2.45e-26FFCP PHASE1:Mm9::chr6:7795251..7795299,+#_21f3545ac2f299551108819ae1f63727p1@C1galt1
2.56e-26FFCP PHASE1:Hg19::chr14:65409484..65409495,-#_a2bcf83a283e8f315e129594d927aed1p2@GPX2
2.56e-26FFCP PHASE2:Hg19::chr14:65409484..65409495,-#_a2bcf83a283e8f315e129594d927aed1p2@GPX2
2.62e-26FFCP PHASE1:Hg19::chr6:116381918..116381977,-#_f4d4ae7739f5e3a6cbeb5a0cd9ac9120p1@FRK
2.62e-26FFCP PHASE2:Hg19::chr6:116381918..116381977,-#_f4d4ae7739f5e3a6cbeb5a0cd9ac9120p1@FRK
2.79e-26FFCP PHASE2:Hg19::chr11:32851450..32851485,+#_4c7e82e4258697f7ac38704ec4ada012p1@PRRG4
2.79e-26FFCP PHASE1:Hg19::chr11:32851450..32851485,+#_4c7e82e4258697f7ac38704ec4ada012p1@PRRG4
3.02e-26FFCP PHASE2:Hg19::chr8:82644741..82644791,+#_b0b9fa2994f65c9533d214901ba51550p2@CHMP4C
3.02e-26FFCP PHASE1:Hg19::chr8:82644741..82644791,+#_b0b9fa2994f65c9533d214901ba51550p2@CHMP4C
3.55e-26FFCP PHASE2:Hg19::chr1:209825762..209825779,-#_3cab60f341827d5bf2d4cd58ff722698p1@LAMB3
3.55e-26FFCP PHASE1:Hg19::chr1:209825762..209825779,-#_3cab60f341827d5bf2d4cd58ff722698p1@LAMB3
4.15e-26FFCP PHASE2:Mm9::chr18:38369387..38369401,-#_29bacea43239dfe1d28190918143b15ap4@Pcdh1
4.15e-26FFCP PHASE1:Mm9::chr18:38369387..38369401,-#_29bacea43239dfe1d28190918143b15ap4@Pcdh1
4.54e-26FFCP PHASE2:Hg19::chr13:76334824..76334862,+#_298026b93bd270a8d010a163d0e2987cp2@LMO7
4.54e-26FFCP PHASE1:Hg19::chr13:76334824..76334862,+#_298026b93bd270a8d010a163d0e2987cp2@LMO7
4.87e-26FFCP PHASE2:Mm9::chr11:106781922..106781957,-#_97b7bff6f6de432c88bec895b9cb4239p4@Smurf2
4.87e-26FFCP PHASE1:Mm9::chr11:106781922..106781957,-#_97b7bff6f6de432c88bec895b9cb4239p4@Smurf2
4.9e-26FFCP PHASE2:Mm9::chr1:58852462..58852483,+#_6bb8ca5ac55230de1107d70add890fe7p4@Casp8
4.9e-26FFCP PHASE1:Mm9::chr1:58852462..58852483,+#_6bb8ca5ac55230de1107d70add890fe7p4@Casp8
5.37e-26FFCP PHASE1:Hg19::chr3:142315294..142315315,+#_97a9853bd4a118db716bba30c38f08a6p3@PLS1
5.37e-26FFCP PHASE2:Hg19::chr3:142315294..142315315,+#_97a9853bd4a118db716bba30c38f08a6p3@PLS1
5.52e-26FFCP PHASE1:Mm9::chr4:124428852..124428893,+#_e88fb6c369d850260deca337b020794cp1@Inpp5b
5.52e-26FFCP PHASE2:Mm9::chr4:124428852..124428893,+#_e88fb6c369d850260deca337b020794cp1@Inpp5b
5.79e-26FFCP PHASE2:Mm9::chr13:101322621..101322632,-#_231f4f0318ad96f9534a8ebec7cb72eep4@Ocln
5.79e-26FFCP PHASE1:Mm9::chr13:101322621..101322632,-#_231f4f0318ad96f9534a8ebec7cb72eep4@Ocln
6.23e-26FFCP PHASE1:Hg19::chr19:3708338..3708374,+#_7550627fb03f3db9cfb3a1ec54b387a2p2@TJP3
6.23e-26FFCP PHASE2:Hg19::chr19:3708338..3708374,+#_7550627fb03f3db9cfb3a1ec54b387a2p2@TJP3
6.37e-26FFCP PHASE2:Mm9::chr10:128180925..128180966,-#_73414929d77b3a75181e7570c439b03ep2@Dgka
6.37e-26FFCP PHASE1:Mm9::chr10:128180925..128180966,-#_73414929d77b3a75181e7570c439b03ep2@Dgka
7.63e-26FFCP PHASE2:Hg19::chr17:19651668..19651682,-#_ba6dffb2430a66703b949f59636c3fa7p2@ALDH3A1
7.63e-26FFCP PHASE1:Hg19::chr17:19651668..19651682,-#_ba6dffb2430a66703b949f59636c3fa7p2@ALDH3A1
8.05e-26FFCP PHASE1:Mm9::chr9:110782790..110782819,+#_0cc3773560144d2b567b7295de613bb4p1@Als2cl
8.05e-26FFCP PHASE2:Mm9::chr9:110782790..110782819,+#_0cc3773560144d2b567b7295de613bb4p1@Als2cl
8.42e-26FFCP PHASE2:Mm9::chr11:116072277..116072320,+#_b9dc99a06d13e5b7aac9386e84cb04fbp2@2310004N24Rik
8.42e-26FFCP PHASE1:Mm9::chr11:116072277..116072320,+#_b9dc99a06d13e5b7aac9386e84cb04fbp2@2310004N24Rik
9.38e-26FFCP PHASE2:Hg19::chr7:1595831..1595858,-#_2dd885c6a2b68c94cd2fce89a848b6c1p1@TMEM184A
9.38e-26FFCP PHASE1:Hg19::chr7:1595831..1595858,-#_2dd885c6a2b68c94cd2fce89a848b6c1p1@TMEM184A
1.03e-25FFCP PHASE1:Hg19::chr10:101690650..101690683,-#_3a87744b64f0e777bc8f919f2b826eabp2@DNMBP
1.03e-25FFCP PHASE2:Hg19::chr10:101690650..101690683,-#_3a87744b64f0e777bc8f919f2b826eabp2@DNMBP
1.14e-25FFCP PHASE2:Hg19::chr1:201979703..201979721,+#_e7c1f777f1e3a14f6c8399741352f179p2@ELF3
1.14e-25FFCP PHASE1:Hg19::chr1:201979703..201979721,+#_e7c1f777f1e3a14f6c8399741352f179p2@ELF3
1.37e-25FFCP PHASE1:Hg19::chr10:114133905..114133922,+#_1b81519c4cee8832b401c746d85cded5p2@ACSL5
1.37e-25FFCP PHASE2:Hg19::chr10:114133905..114133922,+#_1b81519c4cee8832b401c746d85cded5p2@ACSL5
1.44e-25FFCP PHASE2:Hg19::chr18:61144160..61144214,+#_456e9202ba03234212a054094275d773p1@SERPINB5
1.44e-25FFCP PHASE1:Hg19::chr18:61144160..61144214,+#_456e9202ba03234212a054094275d773p1@SERPINB5
1.48e-25FFCP PHASE2:Mm9::chr6:117867010..117867024,+#_905b6fa5c7c1b3cfb2f4941baaa85da7p3@Hnrnpf
1.48e-25FFCP PHASE1:Mm9::chr6:117867010..117867024,+#_905b6fa5c7c1b3cfb2f4941baaa85da7p3@Hnrnpf
1.51e-25FFCP PHASE1:Hg19::chr3:111451321..111451372,+#_a6ce59d37efbf03616f44ca82a853b94p3@PHLDB2
1.51e-25FFCP PHASE2:Hg19::chr3:111451321..111451372,+#_a6ce59d37efbf03616f44ca82a853b94p3@PHLDB2

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