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Revision as of 17:17, 15 June 2012

Name:otic placode
Definition:"A cranial placode which, once specified, invaginates to form an otic cup, which eventually separates from the surface ectoderm to form the otic vesicle or otocyst, a rounded structure without appar- ent polarity. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII" [NBK:NBK53175]
Xrefs:
links:

AAO:0011079
EFO:0003429
EHDAA:506
EHDAA2:0001339
EMAPA:16195
ncithesaurus:Otic_Placodes
TAO:0000138
VHOG:0000235
XAO:0000223

ZFA:0000138
Synonyms: "auditory placode" RELATED []
"ear placode" RELATED []
"ear/otic placode" RELATED []
Comments:With the exception of the pigment cells of the stria vascularis and the secretory epithelium of the cochlea, which are of neural crest origin, all compo- nents of the inner ear derive from the otic placode. In most species the thickening of the ectoderm into a placode occurs in a region adjacent to rhombomere 5 (reviewed in Ohyama et al., 2007), while in amphibians the otic placode is centered onto rhombomere 4 (Ruiz i Altaba and Jessell, 1991).[NBK53175]
Alt_id: UBERON:XAO_0000223-ZFA_0000138
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0003067(dorsolateral placode),UBERON:0005085(ectodermal placode)
part_of:UBERON:0001690(ear)



Children

develops from:UBERON:0009123 (otic cup)
part of:UBERON:0003249 (epithelium of otic placode)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology



Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0003069 (otic placode), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.87e-86FFCP PHASE1:Mm9::chr10:97109753..97109764,+#_79a6708211b885bd34d9bea04e5ffea8p3@Epyc
1.87e-86FFCP PHASE1:Mm9::chr5:147854240..147854249,-#_79a6708211b885bd34d9bea04e5ffea8p@chr5:147854240..147854249, -
1.87e-86FFCP PHASE1:Mm9::chr18:42158627..42158630,-#_79a6708211b885bd34d9bea04e5ffea8p@chr18:42158627..42158630, -
1.87e-86FFCP PHASE1:Mm9::chr2:53464168..53464175,+#_79a6708211b885bd34d9bea04e5ffea8p@chr2:53464168..53464175, +
1.87e-86FFCP PHASE2:Mm9::chr8:13425469..13425503,+#_79a6708211b885bd34d9bea04e5ffea8p@chr8:13425469..13425503, +
1.87e-86FFCP PHASE2:Mm9::chr10:80806020..80806031,-#_79a6708211b885bd34d9bea04e5ffea8p3@Gipc3
1.87e-86FFCP PHASE1:Mm9::chr6:29428397..29428407,-#_79a6708211b885bd34d9bea04e5ffea8p@chr6:29428397..29428407, -
1.87e-86FFCP PHASE2:Mm9::chr10:67371994..67372010,+#_79a6708211b885bd34d9bea04e5ffea8p@chr10:67371994..67372010, +
1.87e-86FFCP PHASE1:Mm9::chr4:63079735..63079745,-#_79a6708211b885bd34d9bea04e5ffea8p@chr4:63079735..63079745, -
1.87e-86FFCP PHASE1:Mm9::chr15:58022966..58022995,-#_79a6708211b885bd34d9bea04e5ffea8p@chr15:58022966..58022995, -
1.87e-86FFCP PHASE2:Mm9::chr15:65641779..65641790,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:65641779..65641790, +
1.87e-86FFCP PHASE1:Mm9::chr15:97806034..97806061,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:97806034..97806061, +
1.87e-86FFCP PHASE2:Mm9::chr3:31585340..31585360,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:31585340..31585360, +
1.87e-86FFCP PHASE2:Mm9::chr1:172843796..172843799,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:172843796..172843799, -
1.87e-86FFCP PHASE1:Mm9::chr13:43699228..43699239,+#_79a6708211b885bd34d9bea04e5ffea8p@chr13:43699228..43699239, +
1.87e-86FFCP PHASE2:Mm9::chr5:30710455..30710464,-#_79a6708211b885bd34d9bea04e5ffea8p9@Otof
1.87e-86FFCP PHASE1:Mm9::chr14:31283072..31283081,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:31283072..31283081, -
1.87e-86FFCP PHASE2:Mm9::chr15:97806034..97806061,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:97806034..97806061, +
1.87e-86FFCP PHASE2:Mm9::chr14:20649897..20649907,+#_79a6708211b885bd34d9bea04e5ffea8p@chr14:20649897..20649907, +
1.87e-86FFCP PHASE2:Mm9::chr10:108316802..108316807,-#_79a6708211b885bd34d9bea04e5ffea8p@chr10:108316802..108316807, -
1.87e-86FFCP PHASE1:Mm9::chr6:113251606..113251613,+#_79a6708211b885bd34d9bea04e5ffea8p@chr6:113251606..113251613, +
1.87e-86FFCP PHASE1:Mm9::chr4:130461150..130461185,+#_79a6708211b885bd34d9bea04e5ffea8p@chr4:130461150..130461185, +
1.87e-86FFCP PHASE1:Mm9::chr17:13983095..13983100,+#_79a6708211b885bd34d9bea04e5ffea8p@chr17:13983095..13983100, +
1.87e-86FFCP PHASE2:Mm9::chr14:63099970..63099980,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:63099970..63099980, -
1.87e-86FFCP PHASE2:Mm9::chr19:10536767..10536777,-#_79a6708211b885bd34d9bea04e5ffea8p@chr19:10536767..10536777, -
1.87e-86FFCP PHASE2:Mm9::chr9:42207852..42207876,-#_79a6708211b885bd34d9bea04e5ffea8p2@Tecta
1.87e-86FFCP PHASE1:Mm9::chr8:13425469..13425503,+#_79a6708211b885bd34d9bea04e5ffea8p@chr8:13425469..13425503, +
1.87e-86FFCP PHASE1:Mm9::chr19:55255289..55255299,+#_79a6708211b885bd34d9bea04e5ffea8p2@Tectb
1.87e-86FFCP PHASE1:Mm9::chr13:78257518..78257522,+#_79a6708211b885bd34d9bea04e5ffea8p@chr13:78257518..78257522, +
1.87e-86FFCP PHASE2:Mm9::chr15:89215333..89215341,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:89215333..89215341, +
1.87e-86FFCP PHASE2:Mm9::chr8:125802236..125802251,-#_79a6708211b885bd34d9bea04e5ffea8p3@Fanca
1.87e-86FFCP PHASE2:Mm9::chr3:35012397..35012405,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:35012397..35012405, +
1.87e-86FFCP PHASE1:Mm9::chr10:107349418..107349423,-#_79a6708211b885bd34d9bea04e5ffea8p5@Otogl
1.87e-86FFCP PHASE2:Mm9::chr4:115556972..115556979,+#_79a6708211b885bd34d9bea04e5ffea8p3@Kncn
1.87e-86FFCP PHASE2:Mm9::chr17:13983102..13983126,+#_79a6708211b885bd34d9bea04e5ffea8p@chr17:13983102..13983126, +
1.87e-86FFCP PHASE1:Mm9::chr9:42207852..42207876,-#_79a6708211b885bd34d9bea04e5ffea8p2@Tecta
1.87e-86FFCP PHASE1:Mm9::chr7:29733825..29733837,-#_79a6708211b885bd34d9bea04e5ffea8p@chr7:29733825..29733837, -
1.87e-86FFCP PHASE1:Mm9::chr1:93235228..93235249,+#_79a6708211b885bd34d9bea04e5ffea8p@chr1:93235228..93235249, +
1.87e-86FFCP PHASE2:Mm9::chr9:42206730..42206739,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:42206730..42206739, -
1.87e-86FFCP PHASE1:Mm9::chr12:109905399..109905416,+#_79a6708211b885bd34d9bea04e5ffea8p@chr12:109905399..109905416, +
1.87e-86FFCP PHASE1:Mm9::chr10:80806047..80806059,-#_79a6708211b885bd34d9bea04e5ffea8p4@Gipc3
1.87e-86FFCP PHASE1:Mm9::chr15:85334335..85334353,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:85334335..85334353, +
1.87e-86FFCP PHASE2:Mm9::chr3:69811606..69811616,+#_79a6708211b885bd34d9bea04e5ffea8p2@Otol1
1.87e-86FFCP PHASE1:Mm9::chr5:28035962..28035983,+#_79a6708211b885bd34d9bea04e5ffea8p@chr5:28035962..28035983, +
1.87e-86FFCP PHASE1:Mm9::chr4:101908153..101908163,+#_79a6708211b885bd34d9bea04e5ffea8p@chr4:101908153..101908163, +
1.87e-86FFCP PHASE2:Mm9::chr18:81327205..81327211,+#_79a6708211b885bd34d9bea04e5ffea8p@chr18:81327205..81327211, +
1.87e-86FFCP PHASE2:Mm9::chr11:11599532..11599539,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:11599532..11599539, -
1.87e-86FFCP PHASE2:Mm9::chr12:77084875..77084885,+#_79a6708211b885bd34d9bea04e5ffea8p@chr12:77084875..77084885, +
1.87e-86FFCP PHASE1:Mm9::chr9:42206730..42206739,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:42206730..42206739, -
1.87e-86FFCP PHASE1:Mm9::chr1:63733478..63733491,-#_79a6708211b885bd34d9bea04e5ffea8p1@Dytn
1.87e-86FFCP PHASE2:Mm9::chr1:93218682..93218691,+#_79a6708211b885bd34d9bea04e5ffea8p2@Espnl
1.87e-86FFCP PHASE2:Mm9::chr11:4689776..4689785,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:4689776..4689785, -
1.87e-86FFCP PHASE2:Mm9::chr4:154208086..154208123,+#_79a6708211b885bd34d9bea04e5ffea8p@chr4:154208086..154208123, +
1.87e-86FFCP PHASE2:Mm9::chr15:85334335..85334353,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:85334335..85334353, +
1.87e-86FFCP PHASE2:Mm9::chr6:113251614..113251623,+#_79a6708211b885bd34d9bea04e5ffea8p@chr6:113251614..113251623, +
1.87e-86FFCP PHASE2:Mm9::chr13:78257454..78257465,+#_79a6708211b885bd34d9bea04e5ffea8p@chr13:78257454..78257465, +
1.87e-86FFCP PHASE2:Mm9::chr13:48087761..48087775,-#_79a6708211b885bd34d9bea04e5ffea8p@chr13:48087761..48087775, -
1.87e-86FFCP PHASE1:Mm9::chr7:109052262..109052291,-#_79a6708211b885bd34d9bea04e5ffea8p1@Tomt
1.87e-86FFCP PHASE1:Mm9::chr2:152453066..152453075,-#_79a6708211b885bd34d9bea04e5ffea8p@chr2:152453066..152453075, -
1.87e-86FFCP PHASE2:Mm9::chr1:63733478..63733491,-#_79a6708211b885bd34d9bea04e5ffea8p1@Dytn
1.87e-86FFCP PHASE1:Mm9::chrX:154140781..154140788,+#_79a6708211b885bd34d9bea04e5ffea8p@chrX:154140781..154140788, +
1.87e-86FFCP PHASE1:Mm9::chr3:69811606..69811616,+#_79a6708211b885bd34d9bea04e5ffea8p2@Otol1
1.87e-86FFCP PHASE1:Mm9::chr13:58283583..58283607,-#_79a6708211b885bd34d9bea04e5ffea8p@chr13:58283583..58283607, -
1.87e-86FFCP PHASE1:Mm9::chr2:29935952..29935993,+#_79a6708211b885bd34d9bea04e5ffea8p7@Pkn3
1.87e-86FFCP PHASE2:Mm9::chr18:38104702..38104718,-#_79a6708211b885bd34d9bea04e5ffea8p@chr18:38104702..38104718, -
1.87e-86FFCP PHASE1:Mm9::chr3:106986057..106986062,+#_79a6708211b885bd34d9bea04e5ffea8p1@Kcna10
1.87e-86FFCP PHASE2:Mm9::chr3:154459246..154459253,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:154459246..154459253, +
1.87e-86FFCP PHASE2:Mm9::chr9:42208023..42208043,-#_79a6708211b885bd34d9bea04e5ffea8p4@Tecta
1.87e-86FFCP PHASE1:Mm9::chr6:86746562..86746579,-#_79a6708211b885bd34d9bea04e5ffea8p@chr6:86746562..86746579, -
1.87e-86FFCP PHASE2:Mm9::chrX:154140800..154140810,+#_79a6708211b885bd34d9bea04e5ffea8p@chrX:154140800..154140810, +
1.87e-86FFCP PHASE1:Mm9::chr1:172843885..172843890,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:172843885..172843890, -
1.87e-86FFCP PHASE2:Mm9::chr18:59222033..59222043,+#_79a6708211b885bd34d9bea04e5ffea8p7@A730017C20Rik
1.87e-86FFCP PHASE2:Mm9::chr1:43454162..43454170,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:43454162..43454170, -
1.87e-86FFCP PHASE1:Mm9::chr11:120222470..120222516,+#_79a6708211b885bd34d9bea04e5ffea8p2@Fscn2
1.87e-86FFCP PHASE2:Mm9::chr10:107349418..107349423,-#_79a6708211b885bd34d9bea04e5ffea8p5@Otogl
1.87e-86FFCP PHASE2:Mm9::chr17:31335869..31335899,-#_79a6708211b885bd34d9bea04e5ffea8p1@Tmprss3
1.87e-86FFCP PHASE2:Mm9::chr14:47293487..47293493,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:47293487..47293493, -
1.87e-86FFCP PHASE1:Mm9::chr9:42208023..42208043,-#_79a6708211b885bd34d9bea04e5ffea8p4@Tecta
1.87e-86FFCP PHASE2:Mm9::chr6:86745686..86745727,-#_79a6708211b885bd34d9bea04e5ffea8p@chr6:86745686..86745727, -
1.87e-86FFCP PHASE2:Mm9::chr9:42207697..42207705,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:42207697..42207705, -
1.87e-86FFCP PHASE1:Mm9::chr12:13508015..13508019,+#_79a6708211b885bd34d9bea04e5ffea8p@chr12:13508015..13508019, +
1.87e-86FFCP PHASE1:Mm9::chr2:121206695..121206711,-#_79a6708211b885bd34d9bea04e5ffea8p1@Strc
1.87e-86FFCP PHASE1:Mm9::chr7:109265277..109265288,-#_79a6708211b885bd34d9bea04e5ffea8p4@Chrna10
1.87e-86FFCP PHASE2:Mm9::chr7:88068153..88068160,-#_79a6708211b885bd34d9bea04e5ffea8p10@Sec11a
1.87e-86FFCP PHASE1:Mm9::chr5:3909290..3909299,+#_79a6708211b885bd34d9bea04e5ffea8p@chr5:3909290..3909299, +
1.87e-86FFCP PHASE1:Mm9::chr4:115556939..115556945,+#_79a6708211b885bd34d9bea04e5ffea8p4@Kncn
1.87e-86FFCP PHASE2:Mm9::chr1:194818647..194818660,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:194818647..194818660, -
1.87e-86FFCP PHASE2:Mm9::chr5:68423014..68423037,+#_79a6708211b885bd34d9bea04e5ffea8p1@Grxcr1
1.87e-86FFCP PHASE1:Mm9::chr9:42207697..42207705,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:42207697..42207705, -
1.87e-86FFCP PHASE1:Mm9::chr7:27964761..27964768,+#_79a6708211b885bd34d9bea04e5ffea8p@chr7:27964761..27964768, +
1.87e-86FFCP PHASE2:Mm9::chr9:50968647..50968668,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:50968647..50968668, -
1.87e-86FFCP PHASE1:Mm9::chr10:67371994..67372010,+#_79a6708211b885bd34d9bea04e5ffea8p@chr10:67371994..67372010, +
1.87e-86FFCP PHASE1:Mm9::chr3:154693281..154693317,-#_79a6708211b885bd34d9bea04e5ffea8p@chr3:154693281..154693317, -
1.87e-86FFCP PHASE1:Mm9::chr5:150945209..150945220,+#_79a6708211b885bd34d9bea04e5ffea8p@chr5:150945209..150945220, +
1.87e-86FFCP PHASE1:Mm9::chr9:41495920..41495928,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:41495920..41495928, -
1.87e-86FFCP PHASE1:Mm9::chr2:53464178..53464186,+#_79a6708211b885bd34d9bea04e5ffea8p@chr2:53464178..53464186, +
1.87e-86FFCP PHASE2:Mm9::chr10:80806047..80806059,-#_79a6708211b885bd34d9bea04e5ffea8p4@Gipc3
1.87e-86FFCP PHASE1:Mm9::chr4:151505798..151505818,-#_79a6708211b885bd34d9bea04e5ffea8p21@Espn
1.87e-86FFCP PHASE2:Mm9::chr9:92087926..92087938,+#_79a6708211b885bd34d9bea04e5ffea8p2@Plscr5
1.87e-86FFCP PHASE2:Mm9::chr3:58626291..58626298,-#_79a6708211b885bd34d9bea04e5ffea8p@chr3:58626291..58626298, -

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