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{{CL
{{CL
|id=CL:0000049
|alt_id=
|name=common myeloid progenitor
|namespace=cell;;efo
|def="A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata-1, Gata2, C/EBPa, and Pu.1." [GOC:add, GOC:dsd, GOC:tfm, ISBN:0878932437, MESH:D023461, PMCID:PMC2212039, PMID:10724173, PMID:16551251]
|xref=
|is_a=CL:0002032
|synonym="cfu-gemm" RELATED [ISBN:0878932437];;"CFU-S" RELATED [ISBN:0878932437];;"CMP" EXACT [ISBN:0878932437];;"colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte" RELATED [ISBN:0878932437];;"common myeloid precursor" EXACT [];;"multipotential myeloid stem cell" RELATED [ISBN:0878932437];;"myeloid stem cell" RELATED [ISBN:0878932437];;"pluripotent stem cell (bone marrow)" RELATED [ISBN:0878932437]
|comment=CMP are reportedly CD38-positive, CD45RA-negative, and CD123-positive.
|comment=CMP are reportedly CD38-positive, CD45RA-negative, and CD123-positive.
|alt_id=
|disjoint_from=CL:0000050;;CL:0000051;;CL:0000557
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata-1, Gata2, C/EBPa, and Pu.1." [GOC:add, GOC:dsd, GOC:tfm, ISBN:0878932437, MESH:D023461, PMCID:PMC2212039, PMID:10724173, PMID:16551251]
|subset=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=CL:0000050;;CL:0000051;;CL:0000557
|has_quality=
|has_quality=
|id=CL:0000049
|is_a=CL:0002032
|is_obsolete=
|located_in=
|located_in=
|name=common myeloid progenitor
|namespace=cell;;efo
|obo_creation_date=
|part_of=
|part_of=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym="cfu-gemm" RELATED [ISBN:0878932437];;"CFU-S" RELATED [ISBN:0878932437];;"CMP" EXACT [ISBN:0878932437];;"colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte" RELATED [ISBN:0878932437];;"common myeloid precursor" EXACT [];;"multipotential myeloid stem cell" RELATED [ISBN:0878932437];;"myeloid stem cell" RELATED [ISBN:0878932437];;"pluripotent stem cell (bone marrow)" RELATED [ISBN:0878932437]
|union_of=
|xref=
}}
}}

Revision as of 10:12, 12 September 2014

Name:common myeloid progenitor
Namespace:cell;;efo
Definition:"A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata-1, Gata2, C/EBPa, and Pu.1." [GOC:add, GOC:dsd, GOC:tfm, ISBN:0878932437, MESH:D023461, PMCID:PMC2212039, PMID:10724173, PMID:16551251]
Synonyms: "cfu-gemm" RELATED [ISBN:0878932437]
"CFU-S" RELATED [ISBN:0878932437]
"CMP" EXACT [ISBN:0878932437]
"colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte" RELATED [ISBN:0878932437]
"common myeloid precursor" EXACT []
"multipotential myeloid stem cell" RELATED [ISBN:0878932437]
"myeloid stem cell" RELATED [ISBN:0878932437]
"pluripotent stem cell (bone marrow)" RELATED [ISBN:0878932437]
Comments:CMP are reportedly CD38-positive, CD45RA-negative, and CD123-positive.


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0002032(hematopoietic oligopotent progenitor cell)
disjoint_from:CL:0000050(megakaryocyte-erythroid progenitor cell),CL:0000051(common lymphoid progenitor),CL:0000557(granulocyte monocyte progenitor cell)



Children


derives from:FF:0000041 (common myeloid progenitor sample)
develops from:CL:0000050 (megakaryocyte-erythroid progenitor cell),CL:0000557 (granulocyte monocyte progenitor cell),CL:0000763 (myeloid cell),CL:0000766 (myeloid leukocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000049 (common myeloid progenitor), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
5.01e-115FFCP PHASE2:Hg19::chr11:47399920..47399931,-#_ff91f69b80faddf40a72d418d9d734eep7@SPI1
5.01e-115FFCP PHASE1:Hg19::chr11:47399920..47399931,-#_ff91f69b80faddf40a72d418d9d734eep7@SPI1
6.88e-112FFCP PHASE2:Hg19::chr11:47400045..47400060,-#_b166924bb2708eb64809f70108a53ff6p6@SPI1
6.88e-112FFCP PHASE1:Hg19::chr11:47400045..47400060,-#_b166924bb2708eb64809f70108a53ff6p6@SPI1
1.87e-103FFCP PHASE2:Hg19::chr8:55074639..55074655,+#_1aaa639b43f39dce40f2491b419ff92ap@chr8:55074639..55074655, +
1.87e-103FFCP PHASE1:Hg19::chr8:55074639..55074655,+#_1aaa639b43f39dce40f2491b419ff92ap@chr8:55074639..55074655, +
5.28e-102FFCP PHASE2:Hg19::chr2:109204876..109204889,+#_819a6d242b10279ffe482258ace6a4dep7@LIMS1
5.28e-102FFCP PHASE1:Hg19::chr2:109204876..109204889,+#_819a6d242b10279ffe482258ace6a4dep7@LIMS1
3.01e-101FFCP PHASE1:Hg19::chr19:54876689..54876707,-#_9f6008e81733936df6eae75167c16e5ap6@LAIR1
3.01e-101FFCP PHASE2:Hg19::chr19:54876689..54876707,-#_9f6008e81733936df6eae75167c16e5ap6@LAIR1
2.92e-100FFCP PHASE2:Hg19::chr17:72528538..72528554,+#_9fa64b1836d74fc90c49be3d8e67787dp@chr17:72528538..72528554, +
2.92e-100FFCP PHASE1:Hg19::chr17:72528538..72528554,+#_9fa64b1836d74fc90c49be3d8e67787dp@chr17:72528538..72528554, +
1.71e-99FFCP PHASE2:Hg19::chr11:47400032..47400043,-#_af45ee27a78c925df11cb84f0c24aaeep5@SPI1
1.71e-99FFCP PHASE1:Hg19::chr11:47400032..47400043,-#_af45ee27a78c925df11cb84f0c24aaeep5@SPI1
3.09e-99FFCP PHASE2:Hg19::chr6:137105174..137105195,+#_3482a2c63c5d8544b35169c61c018282p@chr6:137105174..137105195, +
3.09e-99FFCP PHASE1:Hg19::chr6:137105174..137105195,+#_3482a2c63c5d8544b35169c61c018282p@chr6:137105174..137105195, +
3.6e-99FFCP PHASE1:Hg19::chr19:55084438..55084495,+#_abb6ab241e216fff5d2650b235745aa5p2@LILRA2
3.6e-99FFCP PHASE2:Hg19::chr19:55084438..55084495,+#_abb6ab241e216fff5d2650b235745aa5p2@LILRA2
5.23e-99FFCP PHASE1:Hg19::chr12:118796868..118796885,-#_67603e375b75dbd9c5fa3b7b80f90509p6@TAOK3
5.23e-99FFCP PHASE2:Hg19::chr12:118796868..118796885,-#_67603e375b75dbd9c5fa3b7b80f90509p6@TAOK3
2.14e-98FFCP PHASE1:Hg19::chr18:2847062..2847071,+#_7c02bd86410cc8960ada083d58df4976p7@EMILIN2
2.14e-98FFCP PHASE2:Hg19::chr18:2847062..2847071,+#_7c02bd86410cc8960ada083d58df4976p7@EMILIN2
2.31e-97FFCP PHASE2:Hg19::chr15:65174546..65174583,-#_50a164d97b97576a171afabd1e32db33p@chr15:65174546..65174583, -
2.31e-97FFCP PHASE1:Hg19::chr15:65174546..65174583,-#_50a164d97b97576a171afabd1e32db33p@chr15:65174546..65174583, -
4.87e-97FFCP PHASE2:Hg19::chr20:35202667..35202682,+#_5bb00fbfdad797f66bdf9648a196668ap4@C20orf24
4.87e-97FFCP PHASE1:Hg19::chr20:35202667..35202682,+#_5bb00fbfdad797f66bdf9648a196668ap4@C20orf24
1.04e-96FFCP PHASE1:Hg19::chr13:108922429..108922446,+#_d5ccc8537118e0ab09dc79401ebf4a57p6@TNFSF13B
1.04e-96FFCP PHASE2:Hg19::chr13:108922429..108922446,+#_d5ccc8537118e0ab09dc79401ebf4a57p6@TNFSF13B
1.68e-96FFCP PHASE1:Hg19::chr11:47399947..47399961,-#_f78ceee86c1622760e6350ae45b711cap3@SPI1
1.68e-96FFCP PHASE2:Hg19::chr11:47399947..47399961,-#_f78ceee86c1622760e6350ae45b711cap3@SPI1
3.76e-96FFCP PHASE2:Hg19::chr17:72709134..72709145,-#_c71d0bddb4cb17b2a162481174cc59f4p2@CD300LF
3.76e-96FFCP PHASE1:Hg19::chr17:72709134..72709145,-#_c71d0bddb4cb17b2a162481174cc59f4p2@CD300LF
6.69e-96FFCP PHASE1:Hg19::chr19:36400209..36400286,-#_f831fb44455df1488bf3f582893c40d1p@chr19:36400209..36400286, -
6.69e-96FFCP PHASE2:Hg19::chr19:36400209..36400286,-#_f831fb44455df1488bf3f582893c40d1p@chr19:36400209..36400286, -
7.75e-96FFCP PHASE1:Hg19::chr11:70161074..70161080,-#_eef6a0c70f85208f39092b065d43c48ep@chr11:70161074..70161080, -
7.75e-96FFCP PHASE2:Hg19::chr11:70161074..70161080,-#_eef6a0c70f85208f39092b065d43c48ep@chr11:70161074..70161080, -
7.57e-95FFCP PHASE1:Hg19::chr2:109204909..109204928,+#_81abc69b3f1f31b9556e9f965855f93fp3@LIMS1
7.57e-95FFCP PHASE2:Hg19::chr2:109204909..109204928,+#_81abc69b3f1f31b9556e9f965855f93fp3@LIMS1
1.23e-94FFCP PHASE1:Hg19::chr6:36665587..36665612,+#_b608be6e801b88228ed4f8795401b8ebp1@uc010jwl.1
1.23e-94FFCP PHASE2:Hg19::chr6:36665587..36665612,+#_b608be6e801b88228ed4f8795401b8ebp1@uc010jwl.1
4.83e-94FFCP PHASE2:Hg19::chr22:46998103..46998127,-#_5ebe20ccb7ebcdd3caebf5435894e827p@chr22:46998103..46998127, -
4.83e-94FFCP PHASE1:Hg19::chr22:46998103..46998127,-#_5ebe20ccb7ebcdd3caebf5435894e827p@chr22:46998103..46998127, -
6.81e-94FFCP PHASE1:Hg19::chr5:57787254..57787271,+#_7b14e423478a122547e34f55a1bc06bep2@GAPT
6.81e-94FFCP PHASE2:Hg19::chr5:57787254..57787271,+#_7b14e423478a122547e34f55a1bc06bep2@GAPT
2.22e-93FFCP PHASE1:Hg19::chr6:31583632..31583651,+#_a97a7a02049a0e1902d60e4faa9f567bp5@AIF1
2.22e-93FFCP PHASE2:Hg19::chr6:31583632..31583651,+#_a97a7a02049a0e1902d60e4faa9f567bp5@AIF1
6.0e-93FFCP PHASE2:Hg19::chr16:50313426..50313459,+#_1cc73dca6693892dcd653bf303855aa2p@chr16:50313426..50313459, +
6.0e-93FFCP PHASE1:Hg19::chr16:50313426..50313459,+#_1cc73dca6693892dcd653bf303855aa2p@chr16:50313426..50313459, +
7.03e-93FFCP PHASE2:Hg19::chr11:47399996..47400014,-#_a8efabdefd98260c3cdd23affc67d900p4@SPI1
7.03e-93FFCP PHASE1:Hg19::chr11:47399996..47400014,-#_a8efabdefd98260c3cdd23affc67d900p4@SPI1
9.92e-93FFCP PHASE2:Hg19::chr17:4642716..4642727,-#_474a199f0e3212d66f1383b0ec19ada8p7@CXCL16
9.92e-93FFCP PHASE1:Hg19::chr17:4642716..4642727,-#_474a199f0e3212d66f1383b0ec19ada8p7@CXCL16
1.41e-92FFCP PHASE1:Hg19::chr3:98482159..98482172,+#_55fe533bf4b903fa1502293556a7be94p5@ST3GAL6
1.41e-92FFCP PHASE2:Hg19::chr3:98482159..98482172,+#_55fe533bf4b903fa1502293556a7be94p5@ST3GAL6
1.63e-92FFCP PHASE1:Hg19::chr6:137105206..137105220,+#_4b9a3102c375d0de25b54e8f896ede32p@chr6:137105206..137105220, +
1.63e-92FFCP PHASE2:Hg19::chr6:137105206..137105220,+#_4b9a3102c375d0de25b54e8f896ede32p@chr6:137105206..137105220, +
2.56e-92FFCP PHASE1:Hg19::chr13:108922478..108922493,+#_d29a143ad6df6c2dbb87df043bfcb15dp5@TNFSF13B
2.56e-92FFCP PHASE2:Hg19::chr13:108922478..108922493,+#_d29a143ad6df6c2dbb87df043bfcb15dp5@TNFSF13B
6.37e-92FFCP PHASE1:Hg19::chr22:37257098..37257115,+#_ad20e568cbb4a19f7e08f45503cdbdf0p3@NCF4
6.37e-92FFCP PHASE2:Hg19::chr22:37257098..37257115,+#_ad20e568cbb4a19f7e08f45503cdbdf0p3@NCF4
7.64e-92FFCP PHASE2:Hg19::chr19:36398154..36398173,-#_e76d86c2e49def309b276313a3a70c7dp@chr19:36398154..36398173, -
7.64e-92FFCP PHASE1:Hg19::chr19:36398154..36398173,-#_e76d86c2e49def309b276313a3a70c7dp@chr19:36398154..36398173, -
1.22e-91FFCP PHASE2:Hg19::chr7:2832730..2832791,+#_b616d7edcb62cfbfd11b1d28b876e9b5p@chr7:2832730..2832791, +
1.22e-91FFCP PHASE1:Hg19::chr7:2832730..2832791,+#_b616d7edcb62cfbfd11b1d28b876e9b5p@chr7:2832730..2832791, +
2.01e-91FFCP PHASE1:Hg19::chr17:9923211..9923249,-#_fb0e4c54e2e46764aea3310e6cacdb89p10@GAS7
2.01e-91FFCP PHASE2:Hg19::chr17:9923211..9923249,-#_fb0e4c54e2e46764aea3310e6cacdb89p10@GAS7
4.57e-91FFCP PHASE2:Hg19::chr5:176936817..176936841,-#_d5348db828f6813c8ef605bda471fd7fp2@DOK3
4.57e-91FFCP PHASE1:Hg19::chr5:176936817..176936841,-#_d5348db828f6813c8ef605bda471fd7fp2@DOK3
1.8e-90FFCP PHASE2:Hg19::chr22:37257002..37257013,+#_3e77a1d8cbc1375069f5f8ea7547e424p4@NCF4
1.8e-90FFCP PHASE1:Hg19::chr22:37257002..37257013,+#_3e77a1d8cbc1375069f5f8ea7547e424p4@NCF4
2.43e-90FFCP PHASE1:Hg19::chr19:18286116..18286156,+#_7815d7c2e39a54a31b6db622dfbc8776p@chr19:18286116..18286156, +
2.43e-90FFCP PHASE2:Hg19::chr19:18286116..18286156,+#_7815d7c2e39a54a31b6db622dfbc8776p@chr19:18286116..18286156, +
3.13e-90FFCP PHASE1:Hg19::chr1:161188661..161188679,+#_7dca599d70c41e2441fc1e939159c681p@chr1:161188661..161188679, +
3.13e-90FFCP PHASE2:Hg19::chr1:161188661..161188679,+#_7dca599d70c41e2441fc1e939159c681p@chr1:161188661..161188679, +
9.35e-90FFCP PHASE2:Hg19::chr6:31554766..31554777,+#_94eb06ec747184c56e7dc7505bc6a511p8@LST1
9.35e-90FFCP PHASE1:Hg19::chr6:31554766..31554777,+#_94eb06ec747184c56e7dc7505bc6a511p8@LST1
9.81e-90FFCP PHASE2:Hg19::chr17:6916789..6916808,+#_6a8bf50d8670c7c63c59f22aac823552p10@C17orf49
9.81e-90FFCP PHASE1:Hg19::chr17:6916789..6916808,+#_6a8bf50d8670c7c63c59f22aac823552p10@C17orf49
1.04e-89FFCP PHASE1:Hg19::chr14:103587759..103587770,+#_e5caa461a0cac533e5679411e3953994p@chr14:103587759..103587770, +
1.04e-89FFCP PHASE2:Hg19::chr14:103587759..103587770,+#_e5caa461a0cac533e5679411e3953994p@chr14:103587759..103587770, +
2.62e-89FFCP PHASE2:Hg19::chr19:51714319..51714374,+#_18d43a20622fac8d6a2abd423ba9fe55p@chr19:51714319..51714374, +
2.62e-89FFCP PHASE1:Hg19::chr19:51714319..51714374,+#_18d43a20622fac8d6a2abd423ba9fe55p@chr19:51714319..51714374, +
4.84e-89FFCP PHASE1:Hg19::chr6:137105237..137105263,+#_e34872376821a1eb6cef179d4a049d52p@chr6:137105237..137105263, +
4.84e-89FFCP PHASE2:Hg19::chr6:137105237..137105263,+#_e34872376821a1eb6cef179d4a049d52p@chr6:137105237..137105263, +
4.9e-89FFCP PHASE2:Hg19::chr5:176936844..176936870,-#_80bf5ff7cedadd82ab6d23ef3cc3569cp3@DOK3
4.9e-89FFCP PHASE1:Hg19::chr5:176936844..176936870,-#_80bf5ff7cedadd82ab6d23ef3cc3569cp3@DOK3
7.3e-89FFCP PHASE2:Hg19::chr22:32034409..32034470,-#_7d06bc3b9ba53d55a080a157a50a6e6ep4@PISD
7.3e-89FFCP PHASE1:Hg19::chr22:32034409..32034470,-#_7d06bc3b9ba53d55a080a157a50a6e6ep4@PISD
8.29e-89FFCP PHASE2:Hg19::chr1:161039459..161039478,-#_e3c66d369948d842e941c3ff4071a774p4@ARHGAP30
8.29e-89FFCP PHASE1:Hg19::chr1:161039459..161039478,-#_e3c66d369948d842e941c3ff4071a774p4@ARHGAP30
9.58e-89FFCP PHASE2:Hg19::chr1:161475228..161475239,+#_844734e02afa9411b245a643fd5a029dp3@FCGR2A
9.58e-89FFCP PHASE1:Hg19::chr1:161475228..161475239,+#_844734e02afa9411b245a643fd5a029dp3@FCGR2A
1.26e-88FFCP PHASE2:Hg19::chr18:5466317..5466374,-#_aaef8446aadaa0689253acae7fd02239p@chr18:5466317..5466374, -
1.26e-88FFCP PHASE1:Hg19::chr18:5466317..5466374,-#_aaef8446aadaa0689253acae7fd02239p@chr18:5466317..5466374, -
1.34e-88FFCP PHASE1:Hg19::chr16:8738211..8738249,+#_45b772e189991236f5b2dc43b2f01304p@chr16:8738211..8738249, +
1.34e-88FFCP PHASE2:Hg19::chr16:8738211..8738249,+#_45b772e189991236f5b2dc43b2f01304p@chr16:8738211..8738249, +
2.3e-88FFCP PHASE1:Hg19::chr19:18285955..18285972,+#_f26640c6fc84b8e62b664d90cb65d940p@chr19:18285955..18285972, +
2.3e-88FFCP PHASE2:Hg19::chr19:18285955..18285972,+#_f26640c6fc84b8e62b664d90cb65d940p@chr19:18285955..18285972, +
3.13e-88FFCP PHASE2:Hg19::chr1:28211791..28211853,+#_951ca276c82ad32910ebaa613359df18p@chr1:28211791..28211853, +
3.13e-88FFCP PHASE1:Hg19::chr1:28211791..28211853,+#_951ca276c82ad32910ebaa613359df18p@chr1:28211791..28211853, +

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