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{{UBERON
{{UBERON
|id=UBERON:0001777
|alt_id=UBERON:FMA_58306-MA_0001245
|name=substantia propria of cornea
|namespace=
|def="The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent. It is composed of about 200 flattened lamellテヲ (plates of collagen fibrils), superimposed one on another. They are each about 1.5-2.5 micrometres in thickness. These fibrils run at different angles between the limbi. Fibres of the layers frequently interweave, the anterior lamellテヲ interweaving more than posterior lamellテヲ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamellテヲ. The lamellテヲ are produced by keratocytes (corneal corpuscles), which occupy about 10% of the substantia propria. These lamellテヲ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the sclera. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients. [WP,unvetted]." [Wikipedia:Corneal_stroma]
|xref=EFO:0002514;;EMAPA:17602;;FMA:58306;;GAID:893;;http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Gray871.png/200px-Gray871.png;;MA:0001245;;MESH:A.09.371.060.217.228;;ncithesaurus:Corneal_Stroma;;SCTID:362511000;;ZFA:0001685
|is_a=UBERON:0003566;;UBERON:0003891;;UBERON:0004121
|synonym="corneal stroma" EXACT [];;"stroma of cornea" EXACT [];;"substantia propria" RELATED []
|comment=This class was created automatically from a combination of ontologies
|comment=This class was created automatically from a combination of ontologies
|alt_id=UBERON:FMA_58306-MA_0001245
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent. It is composed of about 200 flattened lamell��スヲ (plates of collagen fibrils), superimposed one on another. They are each about 1.5-2.5 micrometres in thickness. These fibrils run at different angles between the limbi. Fibres of the layers frequently interweave, the anterior lamell��スヲ interweaving more than posterior lamell��スヲ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamell��スヲ. The lamell��スヲ are produced by keratocytes (corneal corpuscles), which occupy about 10% of the substantia propria. These lamell��スヲ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the sclera. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients. [WP,unvetted]." [Wikipedia:Corneal_stroma]
|subset=uberon_slim;;vertebrate_core
|adjacent_to=
|derives_from=
|derives_from=
|develops_from=
|develops_from=UBERON:0007213
|disjoint_from=
|has_quality=
|has_quality=
|id=UBERON:0001777
|is_a=UBERON:0003891 ;;UBERON:0010313
|is_obsolete=
|located_in=
|located_in=
|name=substantia propria of cornea
|namespace=FANTOM
|obo_creation_date=
|part_of=UBERON:0000964
|part_of=UBERON:0000964
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.obo.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|is_obsolete=
|preceded_by=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "Portion of tissue that is located basal to Bowman's layer and distal to Descemet's membrane and is comprised largely of connective tissue.[TAO]" xsd:string
|subset=uberon_slim;;vertebrate_core
|synonym="cornea stroma" EXACT [];;"corneal stroma" EXACT [];;"stroma of cornea" EXACT [];;"substantia propria" RELATED []
|union_of=
|xref=EFO:0002514;;EMAPA:17602;;FMA:58306;;GAID:893;;http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Gray871.png/200px-Gray871.png;;MA:0001245;;MESH:A.09.371.060.217.228;;ncithesaurus:Corneal_Stroma;;SCTID:362511000;;TAO:0002189;;ZFA:0001685
}}
}}

Latest revision as of 17:20, 12 September 2014

Name:substantia propria of cornea
Namespace:FANTOM
Definition:"The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent. It is composed of about 200 flattened lamell��スヲ (plates of collagen fibrils), superimposed one on another. They are each about 1.5-2.5 micrometres in thickness. These fibrils run at different angles between the limbi. Fibres of the layers frequently interweave, the anterior lamell��スヲ interweaving more than posterior lamell��スヲ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamell��スヲ. The lamell��スヲ are produced by keratocytes (corneal corpuscles), which occupy about 10% of the substantia propria. These lamell��スヲ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the sclera. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients. [WP,unvetted]." [Wikipedia:Corneal_stroma]
Xrefs:
links:

EFO:0002514
EMAPA:17602
FMA:58306
GAID:893
[ 200px-Gray871.png 200px-Gray871.png]
MA:0001245
MESH:A.09.371.060.217.228
ncithesaurus:Corneal_Stroma
SCTID:362511000
TAO:0002189

ZFA:0001685
Synonyms: "cornea stroma" EXACT []
"corneal stroma" EXACT []
"stroma of cornea" EXACT []
"substantia propria" RELATED []
Comments:This class was created automatically from a combination of ontologies
Alt_id: UBERON:FMA_58306-MA_0001245
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0003891(stroma),UBERON:0010313(neural crest-derived structure)
develops_from:UBERON:0007213(mesenchyme derived from head neural crest)
part_of:UBERON:0000964(cornea)



Children

part of:CL:0002363 (keratocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001777 (substantia propria of cornea), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data











Property "Property value" (as page type) with input value "UBPROP:0000001 "Portion of tissue that is located basal to Bowman's layer and distal to Descemet's membrane and is comprised largely of connective tissue.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.