Coexpression cluster:C350: Difference between revisions
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{{Coexpression_clusters | {{Coexpression_clusters|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.627700843391758,0.512609386924345,0.592432028477285,0,0,0,0,0,0,0.432051401361264,0.443451609650719,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.440903172569491,0.50304867824351,0.276349023213624,0.432475563704395,0.415237844311434,0.553258278677842,0.633995789349537,0.463610457803615,0.671289416221712,0.441178319094873,0.645812541836877,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.027549189648299,0,0,0,0,0,0.092892723212638,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0848314897427103,0.102328872742628,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.097901023057347,0.201704847121551,0.14963850419244,0,0,0.253610608288505,0,0,0,0.822873586779981,0.197852857276503,0,0,0.0790289888064564,0,0.0833856393724342,0,0,0.0892813554627994,0,0,0.126645485425697,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0789089986057754,0.191050583413854,0,0,0.854499238073003,0,0,0,0,0.112581616328924,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.159051936706215,0,0,0,0,0,0,0,0,0,0,0,0,0,0.159057427468016,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0769963366386578,0,0,0,0,0,0,0,0.0840229578243582,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.11249278032003,0,0,0,0,0,0,0,0,0,0.0329432353726146,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0593938447453515,0,0,0,0,0,0.0440642112897698,0,0.0323630325950716,0.857199851397213,0,0.773222203912138,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.269763851511003,0,0,0,0,0,0,0,0,0,0,0,0,0,0.167629838265644,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.128948885815716,0,0,0,0,0,0,0,0,0,0,0,0.0843723556258797,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.293207375917014,0,0,0,0,0,0,0,0,0.617636126428001,0.286539751937592,0.0413694521212564,0,0,0,0,0.163974701329705,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0317229404497622,0,0,0,0.0839445661171913,0,0.0527623387552046,0.0261550693490902,0,0,0,0,0,0.19648895555617,0.0714254428923096,0,0,0,0,0,0,0,0,0,0.343928797661606,0|full_id=C350_b_lymph_acute_CD19_lymphoma_spleen_B|gostat_on_coexpression_clusters=GO:0006955!immune response!0.00395619922288943!3500;3507;3576$GO:0002376!immune system process!0.00395619922288943!3500;3507;3576$GO:0003823!antigen binding!0.00395619922288943!3500;3507$GO:0045321!leukocyte activation!0.00395619922288943!3507;3576$GO:0042571!immunoglobulin complex, circulating!0.00395619922288943!3507$GO:0001775!cell activation!0.00420175109836318!3507;3576$GO:0005153!interleukin-8 receptor binding!0.00565154680679548!3576$GO:0045022!early endosome to late endosome transport!0.00593394946336459!3507$GO:0019814!immunoglobulin complex!0.00593394946336459!3507$GO:0019815!B cell receptor complex!0.00593394946336459!3507$GO:0045091!regulation of retroviral genome replication!0.00719245428245118!3576$GO:0045090!retroviral genome replication!0.00904548478924136!3576$GO:0042119!neutrophil activation!0.00904548478924136!3576$GO:0042127!regulation of cell proliferation!0.00904548478924136!3507;3576$GO:0050930!induction of positive chemotaxis!0.00941702662374834!3576$GO:0005615!extracellular space!0.00941702662374834!3507;3576$GO:0030890!positive regulation of B cell proliferation!0.00941702662374834!3507$GO:0050926!regulation of positive chemotaxis!0.00941702662374834!3576$GO:0030888!regulation of B cell proliferation!0.00941702662374834!3507$GO:0050927!positive regulation of positive chemotaxis!0.00941702662374834!3576$GO:0050918!positive chemotaxis!0.00941702662374834!3576$GO:0050853!B cell receptor signaling pathway!0.0094576917801139!3507$GO:0050921!positive regulation of chemotaxis!0.0094576917801139!3576$GO:0050920!regulation of chemotaxis!0.009491803941921!3576$GO:0030593!neutrophil chemotaxis!0.009491803941921!3576$GO:0045069!regulation of viral genome replication!0.00988700469035434!3576$GO:0005624!membrane fraction!0.00991146325799091!3500;3507$GO:0008283!cell proliferation!0.0104670522674057!3507;3576$GO:0050792!regulation of viral reproduction!0.0104670522674057!3576$GO:0001772!immunological synapse!0.0104670522674057!3507$GO:0050731!positive regulation of peptidyl-tyrosine phosphorylation!0.0104670522674057!3507$GO:0045807!positive regulation of endocytosis!0.0104670522674057!3507$GO:0050871!positive regulation of B cell activation!0.0104670522674057!3507$GO:0042100!B cell proliferation!0.0104670522674057!3507$GO:0042327!positive regulation of phosphorylation!0.0115598019496547!3507$GO:0030595!leukocyte chemotaxis!0.0115598019496547!3576$GO:0000267!cell fraction!0.0115598019496547!3500;3507$GO:0044421!extracellular region part!0.0115598019496547!3507;3576$GO:0045937!positive regulation of phosphate metabolic process!0.0115598019496547!3507$GO:0050864!regulation of B cell activation!0.0115598019496547!3507$GO:0001934!positive regulation of protein amino acid phosphorylation!0.0115598019496547!3507$GO:0002274!myeloid leukocyte activation!0.0115598019496547!3576$GO:0033240!positive regulation of amine metabolic process!0.0115598019496547!3507$GO:0045764!positive regulation of amino acid metabolic process!0.0115598019496547!3507$GO:0050851!antigen receptor-mediated signaling pathway!0.0115598019496547!3507$GO:0050730!regulation of peptidyl-tyrosine phosphorylation!0.0115598019496547!3507$GO:0019079!viral genome replication!0.0115598019496547!3576$GO:0032946!positive regulation of mononuclear cell proliferation!0.0115598019496547!3507$GO:0002455!humoral immune response mediated by circulating immunoglobulin!0.0115598019496547!3507$GO:0002429!immune response-activating cell surface receptor signaling pathway!0.0115598019496547!3507$GO:0050671!positive regulation of lymphocyte proliferation!0.0115598019496547!3507$GO:0050900!leukocyte migration!0.0115598019496547!3576$GO:0002768!immune response-regulating cell surface receptor signaling pathway!0.0115598019496547!3507$GO:0002757!immune response-activating signal transduction!0.011711378025305!3507$GO:0002764!immune response-regulating signal transduction!0.0118574210887758!3507$GO:0030100!regulation of endocytosis!0.0119982275520463!3507$GO:0019722!calcium-mediated signaling!0.0128266931832893!3576$GO:0051050!positive regulation of transport!0.0129458524290536!3507$GO:0016197!endosome transport!0.013383863320157!3507$GO:0018108!peptidyl-tyrosine phosphorylation!0.013383863320157!3507$GO:0050670!regulation of lymphocyte proliferation!0.013383863320157!3507$GO:0032944!regulation of mononuclear cell proliferation!0.013383863320157!3507$GO:0018212!peptidyl-tyrosine modification!0.0137685000000387!3507$GO:0001932!regulation of protein amino acid phosphorylation!0.0137685000000387!3507$GO:0033238!regulation of amine metabolic process!0.0137685000000387!3507$GO:0006521!regulation of amino acid metabolic process!0.0137685000000387!3507$GO:0019058!viral infectious cycle!0.014339572658952!3576$GO:0009897!external side of plasma membrane!0.014339572658952!3507$GO:0051251!positive regulation of lymphocyte activation!0.014339572658952!3507$GO:0016064!immunoglobulin mediated immune response!0.014339572658952!3507$GO:0019724!B cell mediated immunity!0.014339572658952!3507$GO:0032943!mononuclear cell proliferation!0.014339572658952!3507$GO:0046651!lymphocyte proliferation!0.014339572658952!3507$GO:0000187!activation of MAPK activity!0.0150087881311616!3507$GO:0022415!viral reproductive process!0.0150087881311616!3576$GO:0042113!B cell activation!0.0158488264866682!3507$GO:0042325!regulation of phosphorylation!0.0162004792785023!3507$GO:0048471!perinuclear region of cytoplasm!0.0162004792785023!3507$GO:0043406!positive regulation of MAP kinase activity!0.0162881160672838!3507$GO:0030155!regulation of cell adhesion!0.0162881160672838!3576$GO:0051174!regulation of phosphorus metabolic process!0.0166116880525676!3507$GO:0019220!regulation of phosphate metabolic process!0.0166116880525676!3507$GO:0002253!activation of immune response!0.0168543714380707!3507$GO:0002449!lymphocyte mediated immunity!0.0168543714380707!3507$GO:0006959!humoral immune response!0.0168543714380707!3507$GO:0002250!adaptive immune response!0.0168543714380707!3507$GO:0008009!chemokine activity!0.0168543714380707!3576$GO:0002460!adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains!0.0168543714380707!3507$GO:0051249!regulation of lymphocyte activation!0.0168543714380707!3507$GO:0042379!chemokine receptor binding!0.0168859071514165!3576$GO:0002443!leukocyte mediated immunity!0.016916737003196!3507$GO:0050865!regulation of cell activation!0.0171608959655122!3507$GO:0050778!positive regulation of immune response!0.0178428776647907!3507$GO:0051247!positive regulation of protein metabolic process!0.0178428776647907!3507$GO:0002684!positive regulation of immune system process!0.0178622382061167!3507$GO:0043405!regulation of MAP kinase activity!0.0191109896713727!3507$GO:0050776!regulation of immune response!0.0199279131796443!3507$GO:0002682!regulation of immune system process!0.0201212644956015!3507$GO:0007050!cell cycle arrest!0.0201212644956015!3576$GO:0001664!G-protein-coupled receptor binding!0.0205015089564397!3576$GO:0051240!positive regulation of multicellular organismal process!0.0205015089564397!3507$GO:0007242!intracellular signaling cascade!0.0206565267277989!3507;3576$GO:0043235!receptor complex!0.0206565267277989!3507$GO:0002252!immune effector process!0.0206565267277989!3507$GO:0051049!regulation of transport!0.0206565267277989!3507$GO:0018193!peptidyl-amino acid modification!0.0225005239824122!3507$GO:0001525!angiogenesis!0.0237583710023897!3576$GO:0045860!positive regulation of protein kinase activity!0.0255539605278058!3507$GO:0033674!positive regulation of kinase activity!0.0255539605278058!3507$GO:0042330!taxis!0.0255539605278058!3576$GO:0006935!chemotaxis!0.0255539605278058!3576$GO:0051347!positive regulation of transferase activity!0.0255696250733866!3507$GO:0048514!blood vessel morphogenesis!0.0255696250733866!3576$GO:0009986!cell surface!0.0255696250733866!3507$GO:0000165!MAPKKK cascade!0.0256882967032008!3507$GO:0048646!anatomical structure formation!0.0259738855056701!3576$GO:0046649!lymphocyte activation!0.0260869742473664!3507$GO:0001568!blood vessel development!0.0273422372844919!3576$GO:0001944!vasculature development!0.0273422372844919!3576$GO:0007166!cell surface receptor linked signal transduction!0.0273422372844919!3507;3576$GO:0007626!locomotory behavior!0.029433244533981!3576$GO:0010324!membrane invagination!0.0314993158407173!3507$GO:0006897!endocytosis!0.0314993158407173!3507$GO:0005515!protein binding!0.0336362671547079!3500;3507;3576$GO:0045786!negative regulation of progression through cell cycle!0.0350908007506085!3576$GO:0008285!negative regulation of cell proliferation!0.0350908007506085!3576$GO:0016477!cell migration!0.0357622432664774!3576$GO:0008284!positive regulation of cell proliferation!0.0357622432664774!3507$GO:0045859!regulation of protein kinase activity!0.0360899418582341!3507$GO:0043549!regulation of kinase activity!0.0365624667764168!3507$GO:0051338!regulation of transferase activity!0.0370275569021061!3507$GO:0043085!positive regulation of catalytic activity!0.0380758925119667!3507$GO:0019932!second-messenger-mediated signaling!0.0395469873936715!3576$GO:0051239!regulation of multicellular organismal process!0.0405592445225359!3507$GO:0016044!membrane organization and biogenesis!0.0412676483960112!3507$GO:0006954!inflammatory response!0.0419652184692328!3576$GO:0007610!behavior!0.0420846488799162!3576$GO:0022414!reproductive process!0.0433287996253402!3576$GO:0005125!cytokine activity!0.0437158255262933!3576$GO:0000074!regulation of progression through cell cycle!0.0493613408533506!3576$GO:0051726!regulation of cell cycle!0.049835479474263!3576$GO:0009887!organ morphogenesis!0.0498936231862632!3576$GO:0031325!positive regulation of cellular metabolic 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Latest revision as of 11:20, 17 September 2013
Full id: C350_b_lymph_acute_CD19_lymphoma_spleen_B
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
No results for this coexpression
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0006955 | immune response | 0.00395619922288943 |
GO:0002376 | immune system process | 0.00395619922288943 |
GO:0003823 | antigen binding | 0.00395619922288943 |
GO:0045321 | leukocyte activation | 0.00395619922288943 |
GO:0042571 | immunoglobulin complex, circulating | 0.00395619922288943 |
GO:0001775 | cell activation | 0.00420175109836318 |
GO:0005153 | interleukin-8 receptor binding | 0.00565154680679548 |
GO:0045022 | early endosome to late endosome transport | 0.00593394946336459 |
GO:0019814 | immunoglobulin complex | 0.00593394946336459 |
GO:0019815 | B cell receptor complex | 0.00593394946336459 |
GO:0045091 | regulation of retroviral genome replication | 0.00719245428245118 |
GO:0045090 | retroviral genome replication | 0.00904548478924136 |
GO:0042119 | neutrophil activation | 0.00904548478924136 |
GO:0042127 | regulation of cell proliferation | 0.00904548478924136 |
GO:0050930 | induction of positive chemotaxis | 0.00941702662374834 |
GO:0005615 | extracellular space | 0.00941702662374834 |
GO:0030890 | positive regulation of B cell proliferation | 0.00941702662374834 |
GO:0050926 | regulation of positive chemotaxis | 0.00941702662374834 |
GO:0030888 | regulation of B cell proliferation | 0.00941702662374834 |
GO:0050927 | positive regulation of positive chemotaxis | 0.00941702662374834 |
GO:0050918 | positive chemotaxis | 0.00941702662374834 |
GO:0050853 | B cell receptor signaling pathway | 0.0094576917801139 |
GO:0050921 | positive regulation of chemotaxis | 0.0094576917801139 |
GO:0050920 | regulation of chemotaxis | 0.009491803941921 |
GO:0030593 | neutrophil chemotaxis | 0.009491803941921 |
GO:0045069 | regulation of viral genome replication | 0.00988700469035434 |
GO:0005624 | membrane fraction | 0.00991146325799091 |
GO:0008283 | cell proliferation | 0.0104670522674057 |
GO:0050792 | regulation of viral reproduction | 0.0104670522674057 |
GO:0001772 | immunological synapse | 0.0104670522674057 |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 0.0104670522674057 |
GO:0045807 | positive regulation of endocytosis | 0.0104670522674057 |
GO:0050871 | positive regulation of B cell activation | 0.0104670522674057 |
GO:0042100 | B cell proliferation | 0.0104670522674057 |
GO:0042327 | positive regulation of phosphorylation | 0.0115598019496547 |
GO:0030595 | leukocyte chemotaxis | 0.0115598019496547 |
GO:0000267 | cell fraction | 0.0115598019496547 |
GO:0044421 | extracellular region part | 0.0115598019496547 |
GO:0045937 | positive regulation of phosphate metabolic process | 0.0115598019496547 |
GO:0050864 | regulation of B cell activation | 0.0115598019496547 |
GO:0001934 | positive regulation of protein amino acid phosphorylation | 0.0115598019496547 |
GO:0002274 | myeloid leukocyte activation | 0.0115598019496547 |
GO:0033240 | positive regulation of amine metabolic process | 0.0115598019496547 |
GO:0045764 | positive regulation of amino acid metabolic process | 0.0115598019496547 |
GO:0050851 | antigen receptor-mediated signaling pathway | 0.0115598019496547 |
GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 0.0115598019496547 |
GO:0019079 | viral genome replication | 0.0115598019496547 |
GO:0032946 | positive regulation of mononuclear cell proliferation | 0.0115598019496547 |
GO:0002455 | humoral immune response mediated by circulating immunoglobulin | 0.0115598019496547 |
GO:0002429 | immune response-activating cell surface receptor signaling pathway | 0.0115598019496547 |
GO:0050671 | positive regulation of lymphocyte proliferation | 0.0115598019496547 |
GO:0050900 | leukocyte migration | 0.0115598019496547 |
GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 0.0115598019496547 |
GO:0002757 | immune response-activating signal transduction | 0.011711378025305 |
GO:0002764 | immune response-regulating signal transduction | 0.0118574210887758 |
GO:0030100 | regulation of endocytosis | 0.0119982275520463 |
GO:0019722 | calcium-mediated signaling | 0.0128266931832893 |
GO:0051050 | positive regulation of transport | 0.0129458524290536 |
GO:0016197 | endosome transport | 0.013383863320157 |
GO:0018108 | peptidyl-tyrosine phosphorylation | 0.013383863320157 |
GO:0050670 | regulation of lymphocyte proliferation | 0.013383863320157 |
GO:0032944 | regulation of mononuclear cell proliferation | 0.013383863320157 |
GO:0018212 | peptidyl-tyrosine modification | 0.0137685000000387 |
GO:0001932 | regulation of protein amino acid phosphorylation | 0.0137685000000387 |
GO:0033238 | regulation of amine metabolic process | 0.0137685000000387 |
GO:0006521 | regulation of amino acid metabolic process | 0.0137685000000387 |
GO:0019058 | viral infectious cycle | 0.014339572658952 |
GO:0009897 | external side of plasma membrane | 0.014339572658952 |
GO:0051251 | positive regulation of lymphocyte activation | 0.014339572658952 |
GO:0016064 | immunoglobulin mediated immune response | 0.014339572658952 |
GO:0019724 | B cell mediated immunity | 0.014339572658952 |
GO:0032943 | mononuclear cell proliferation | 0.014339572658952 |
GO:0046651 | lymphocyte proliferation | 0.014339572658952 |
GO:0000187 | activation of MAPK activity | 0.0150087881311616 |
GO:0022415 | viral reproductive process | 0.0150087881311616 |
GO:0042113 | B cell activation | 0.0158488264866682 |
GO:0042325 | regulation of phosphorylation | 0.0162004792785023 |
GO:0048471 | perinuclear region of cytoplasm | 0.0162004792785023 |
GO:0043406 | positive regulation of MAP kinase activity | 0.0162881160672838 |
GO:0030155 | regulation of cell adhesion | 0.0162881160672838 |
GO:0051174 | regulation of phosphorus metabolic process | 0.0166116880525676 |
GO:0019220 | regulation of phosphate metabolic process | 0.0166116880525676 |
GO:0002253 | activation of immune response | 0.0168543714380707 |
GO:0002449 | lymphocyte mediated immunity | 0.0168543714380707 |
GO:0006959 | humoral immune response | 0.0168543714380707 |
GO:0002250 | adaptive immune response | 0.0168543714380707 |
GO:0008009 | chemokine activity | 0.0168543714380707 |
GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.0168543714380707 |
GO:0051249 | regulation of lymphocyte activation | 0.0168543714380707 |
GO:0042379 | chemokine receptor binding | 0.0168859071514165 |
GO:0002443 | leukocyte mediated immunity | 0.016916737003196 |
GO:0050865 | regulation of cell activation | 0.0171608959655122 |
GO:0050778 | positive regulation of immune response | 0.0178428776647907 |
GO:0051247 | positive regulation of protein metabolic process | 0.0178428776647907 |
GO:0002684 | positive regulation of immune system process | 0.0178622382061167 |
GO:0043405 | regulation of MAP kinase activity | 0.0191109896713727 |
GO:0050776 | regulation of immune response | 0.0199279131796443 |
GO:0002682 | regulation of immune system process | 0.0201212644956015 |
GO:0007050 | cell cycle arrest | 0.0201212644956015 |
GO:0001664 | G-protein-coupled receptor binding | 0.0205015089564397 |
GO:0051240 | positive regulation of multicellular organismal process | 0.0205015089564397 |
GO:0007242 | intracellular signaling cascade | 0.0206565267277989 |
GO:0043235 | receptor complex | 0.0206565267277989 |
GO:0002252 | immune effector process | 0.0206565267277989 |
GO:0051049 | regulation of transport | 0.0206565267277989 |
GO:0018193 | peptidyl-amino acid modification | 0.0225005239824122 |
GO:0001525 | angiogenesis | 0.0237583710023897 |
GO:0045860 | positive regulation of protein kinase activity | 0.0255539605278058 |
GO:0033674 | positive regulation of kinase activity | 0.0255539605278058 |
GO:0042330 | taxis | 0.0255539605278058 |
GO:0006935 | chemotaxis | 0.0255539605278058 |
GO:0051347 | positive regulation of transferase activity | 0.0255696250733866 |
GO:0048514 | blood vessel morphogenesis | 0.0255696250733866 |
GO:0009986 | cell surface | 0.0255696250733866 |
GO:0000165 | MAPKKK cascade | 0.0256882967032008 |
GO:0048646 | anatomical structure formation | 0.0259738855056701 |
GO:0046649 | lymphocyte activation | 0.0260869742473664 |
GO:0001568 | blood vessel development | 0.0273422372844919 |
GO:0001944 | vasculature development | 0.0273422372844919 |
GO:0007166 | cell surface receptor linked signal transduction | 0.0273422372844919 |
GO:0007626 | locomotory behavior | 0.029433244533981 |
GO:0010324 | membrane invagination | 0.0314993158407173 |
GO:0006897 | endocytosis | 0.0314993158407173 |
GO:0005515 | protein binding | 0.0336362671547079 |
GO:0045786 | negative regulation of progression through cell cycle | 0.0350908007506085 |
GO:0008285 | negative regulation of cell proliferation | 0.0350908007506085 |
GO:0016477 | cell migration | 0.0357622432664774 |
GO:0008284 | positive regulation of cell proliferation | 0.0357622432664774 |
GO:0045859 | regulation of protein kinase activity | 0.0360899418582341 |
GO:0043549 | regulation of kinase activity | 0.0365624667764168 |
GO:0051338 | regulation of transferase activity | 0.0370275569021061 |
GO:0043085 | positive regulation of catalytic activity | 0.0380758925119667 |
GO:0019932 | second-messenger-mediated signaling | 0.0395469873936715 |
GO:0051239 | regulation of multicellular organismal process | 0.0405592445225359 |
GO:0016044 | membrane organization and biogenesis | 0.0412676483960112 |
GO:0006954 | inflammatory response | 0.0419652184692328 |
GO:0007610 | behavior | 0.0420846488799162 |
GO:0022414 | reproductive process | 0.0433287996253402 |
GO:0005125 | cytokine activity | 0.0437158255262933 |
GO:0000074 | regulation of progression through cell cycle | 0.0493613408533506 |
GO:0051726 | regulation of cell cycle | 0.049835479474263 |
GO:0009887 | organ morphogenesis | 0.0498936231862632 |
GO:0031325 | positive regulation of cellular metabolic process | 0.0499508811830772 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
---|---|---|
lymphocyte of B lineage | 5.72e-67 | 24 |
pro-B cell | 5.72e-67 | 24 |
B cell | 1.97e-40 | 14 |
lymphocyte | 7.51e-30 | 53 |
common lymphoid progenitor | 7.51e-30 | 53 |
nucleate cell | 1.55e-28 | 55 |
lymphoid lineage restricted progenitor cell | 1.27e-27 | 52 |
nongranular leukocyte | 7.60e-14 | 115 |
hematopoietic stem cell | 6.71e-11 | 168 |
angioblastic mesenchymal cell | 6.71e-11 | 168 |
leukocyte | 1.00e-10 | 136 |
hematopoietic cell | 5.54e-10 | 177 |
hematopoietic oligopotent progenitor cell | 8.54e-10 | 161 |
hematopoietic multipotent progenitor cell | 8.54e-10 | 161 |
hematopoietic lineage restricted progenitor cell | 1.28e-09 | 120 |
Ontology term | p-value | n |
---|---|---|
adult organism | 1.07e-12 | 114 |
hemopoietic organ | 1.91e-11 | 7 |
immune organ | 1.91e-11 | 7 |
spleen | 7.46e-11 | 3 |
gastrointestinal system mesentery | 7.46e-11 | 3 |
stomach region | 7.46e-11 | 3 |
mesentery | 7.46e-11 | 3 |
gastrointestinal system serosa | 7.46e-11 | 3 |
mesentery of stomach | 7.46e-11 | 3 |
gut mesentery | 7.46e-11 | 3 |
dorsal mesentery | 7.46e-11 | 3 |
dorsal mesogastrium | 7.46e-11 | 3 |
peritoneal cavity | 7.46e-11 | 3 |
spleen primordium | 7.46e-11 | 3 |
blood | 2.22e-07 | 15 |
haemolymphatic fluid | 2.22e-07 | 15 |
organism substance | 2.22e-07 | 15 |
Ontology term | p-value | n |
---|---|---|
lymphoma | 2.13e-08 | 10 |
hematologic cancer | 6.18e-07 | 51 |
immune system cancer | 6.18e-07 | 51 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.00040238 |
MA0004.1 | 11.2345 |
MA0006.1 | 0.279119 |
MA0007.1 | 0.265481 |
MA0009.1 | 0.395891 |
MA0014.1 | 0.00277835 |
MA0017.1 | 2.99133 |
MA0019.1 | 2.91722 |
MA0024.1 | 0.312615 |
MA0025.1 | 0.508683 |
MA0027.1 | 1.93196 |
MA0028.1 | 0.032054 |
MA0029.1 | 0.327543 |
MA0030.1 | 0.318663 |
MA0031.1 | 0.270046 |
MA0038.1 | 3.39844 |
MA0040.1 | 0.332103 |
MA0041.1 | 0.0940493 |
MA0042.1 | 0.0792314 |
MA0043.1 | 1.02525 |
MA0046.1 | 0.386991 |
MA0048.1 | 0.915538 |
MA0050.1 | 0.0796249 |
MA0051.1 | 0.136135 |
MA0052.1 | 0.335128 |
MA0055.1 | 0.828339 |
MA0056.1 | 0 |
MA0057.1 | 2.06674 |
MA0058.1 | 20.4269 |
MA0059.1 | 6.04104 |
MA0060.1 | 0.00694078 |
MA0061.1 | 4.04258 |
MA0063.1 | 0 |
MA0066.1 | 2.65769 |
MA0067.1 | 0.673046 |
MA0068.1 | 0.0455946 |
MA0069.1 | 0.383853 |
MA0070.1 | 0.374777 |
MA0071.1 | 0.1171 |
MA0072.1 | 0.371146 |
MA0073.1 | 1.696e-05 |
MA0074.1 | 2.62648 |
MA0076.1 | 0.0525452 |
MA0077.1 | 0.364942 |
MA0078.1 | 0.197204 |
MA0081.1 | 0.0465806 |
MA0083.1 | 0.40206 |
MA0084.1 | 0.847335 |
MA0087.1 | 0.369175 |
MA0088.1 | 1.26589 |
MA0089.1 | 0 |
MA0090.1 | 0.0579073 |
MA0091.1 | 0.0865076 |
MA0092.1 | 6.0767 |
MA0093.1 | 14.38 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 4.3091 |
MA0101.1 | 1.2308 |
MA0103.1 | 9.58 |
MA0105.1 | 3.84914 |
MA0106.1 | 0.163029 |
MA0107.1 | 3.5716 |
MA0108.2 | 0.267801 |
MA0109.1 | 0 |
MA0111.1 | 0.490476 |
MA0113.1 | 0.173209 |
MA0114.1 | 1.169 |
MA0115.1 | 0.603788 |
MA0116.1 | 2.5408 |
MA0117.1 | 0.427006 |
MA0119.1 | 0.0412526 |
MA0122.1 | 1.99005 |
MA0124.1 | 0.566745 |
MA0125.1 | 0.493194 |
MA0130.1 | 0 |
MA0131.1 | 0.2093 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.420972 |
MA0136.1 | 0.142619 |
MA0139.1 | 0.00355142 |
MA0140.1 | 0.115685 |
MA0141.1 | 1.52412 |
MA0142.1 | 2.76951 |
MA0143.1 | 1.57513 |
MA0144.1 | 0.144799 |
MA0145.1 | 2.37335 |
MA0146.1 | 0.443429 |
MA0147.1 | 6.922 |
MA0148.1 | 0.0971411 |
MA0149.1 | 0.110599 |
MA0062.2 | 0.004042 |
MA0035.2 | 0.11531 |
MA0039.2 | 0.00370508 |
MA0138.2 | 0.575161 |
MA0002.2 | 0.361695 |
MA0137.2 | 0.136268 |
MA0104.2 | 3.40818 |
MA0047.2 | 0.155654 |
MA0112.2 | 1.33369 |
MA0065.2 | 0.163186 |
MA0150.1 | 0.44969 |
MA0151.1 | 0 |
MA0152.1 | 0.119196 |
MA0153.1 | 0.478697 |
MA0154.1 | 0.737639 |
MA0155.1 | 0.000754999 |
MA0156.1 | 0.0345163 |
MA0157.1 | 0.227782 |
MA0158.1 | 0 |
MA0159.1 | 3.10997 |
MA0160.1 | 1.14983 |
MA0161.1 | 0 |
MA0162.1 | 0.00415725 |
MA0163.1 | 1.71831 |
MA0164.1 | 0.181076 |
MA0080.2 | 0.838393 |
MA0018.2 | 6.37996 |
MA0099.2 | 0.119388 |
MA0079.2 | 5.55621e-08 |
MA0102.2 | 0.88257 |
MA0258.1 | 1.02444 |
MA0259.1 | 2.16494 |
MA0442.1 | 0 |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)
TF | #promoters | Enrichment | p-value | q-value |
---|---|---|---|---|
POLR2A#5430 | 32 | 2.14745317655807 | 2.38288969218142e-11 | 2.83124705986046e-09 |
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
This analysis result is provided for C0 - C305 clusters.