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MCL coexpression mm9:116: Difference between revisions

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{{MCL_coexpression_mm9
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signaling cascade;0.000293664869207983;72674,67844,17874,14784,57912,77407,56632,14676,14678,19303,56212,23999,15162,74039,219144!GO:0030036;actin cytoskeleton organization and biogenesis;0.00402727299685778;56378,18643,56212,21894,19261,12332!GO:0030029;actin filament-based process;0.00402727299685778;56378,18643,56212,21894,19261,12332!GO:0002253;activation of immune response;0.0130000415564871;18636,17874,74039,14127!GO:0003779;actin binding;0.0130000415564871;56378,18643,72042,23999,21894,12332!GO:0008064;regulation of actin polymerization and/or depolymerization;0.0130000415564871;56378,18643,12332!GO:0030832;regulation of actin filament length;0.0130000415564871;56378,18643,12332!GO:0032535;regulation of cellular component size;0.0130000415564871;56378,18643,12332!GO:0032956;regulation of actin cytoskeleton organization and biogenesis;0.0130000415564871;56378,18643,12332!GO:0033043;regulation of organelle organization and biogenesis;0.0130000415564871;56378,18643,12332!GO:0051493;regulation of cytoskeleton organization and biogenesis;0.0130000415564871;56378,18643,12332!GO:0002757;immune response-activating signal transduction;0.0131962910207542;17874,74039,14127!GO:0002764;immune response-regulating signal transduction;0.0131962910207542;17874,74039,14127!GO:0050778;positive regulation of immune response;0.0131962910207542;18636,17874,74039,14127!GO:0002684;positive regulation of immune system process;0.0131962910207542;18636,17874,74039,14127!GO:0032760;positive regulation of tumor necrosis factor production;0.0131962910207542;17874,14127!GO:0008154;actin polymerization and/or depolymerization;0.0131962910207542;56378,18643,12332!GO:0048518;positive regulation of biological process;0.0131962910207542;17874,56632,19261,18636,56212,20354,14127,74039,20375!GO:0032680;regulation of tumor necrosis factor production;0.0173595877607959;17874,14127!GO:0030833;regulation of actin filament polymerization;0.0173595877607959;56378,18643!GO:0050776;regulation of immune response;0.0173595877607959;18636,17874,74039,14127!GO:0002682;regulation of immune system process;0.0177121463524503;18636,17874,74039,14127!GO:0005525;GTP binding;0.0177121463524503;14678,14676,56212,67844,77407,219144!GO:0051240;positive regulation of multicellular organismal process;0.0177121463524503;18636,17874,74039,14127!GO:0007010;cytoskeleton organization and biogenesis;0.0177121463524503;56378,19303,18643,56212,21894,19261,12332!GO:0000165;MAPKKK cascade;0.0177121463524503;19303,17874,14784,57912!GO:0019001;guanyl nucleotide binding;0.0177121463524503;14678,14676,56212,67844,77407,219144!GO:0032561;guanyl ribonucleotide binding;0.0177121463524503;14678,14676,56212,67844,77407,219144!GO:0051128;regulation of cellular component organization and biogenesis;0.0190686644568285;56378,18643,12332!GO:0008092;cytoskeletal protein binding;0.0190686644568285;56378,18643,72042,23999,21894,12332!GO:0007264;small GTPase mediated signal transduction;0.0193338699831508;56212,67844,14784,57912,77407,219144!GO:0009620;response to fungus;0.0195759985896822;72042,17874!GO:0006911;phagocytosis, engulfment;0.0221005852117815;19261,14127!GO:0030148;sphingolipid biosynthetic process;0.0239935659051621;56632,14421!GO:0032640;tumor necrosis factor production;0.0239935659051621;17874,14127!GO:0050764;regulation of phagocytosis;0.0258851381173991;19261,14127!GO:0050766;positive regulation of phagocytosis;0.0258851381173991;19261,14127!GO:0030041;actin filament polymerization;0.028505187330231;56378,18643!GO:0046328;regulation of JNK cascade;0.0311812294906226;17874,57912!GO:0001819;positive regulation of cytokine production;0.0359149485320526;17874,14127!GO:0051091;positive regulation of transcription factor activity;0.0359149485320526;17874,74039!GO:0031252;leading edge;0.0359149485320526;56378,19303,21894!GO:0051707;response to other organism;0.0359149485320526;72042,17874,68576,14127!GO:0045807;positive regulation of endocytosis;0.0359149485320526;19261,14127!GO:0007154;cell communication;0.0359149485320526;67844,77407,11501,17972,14676,14678,23999,106512,74039,219144,216869,72674,57912,14784,17874,56632,80910,19303,56212,15162,14127,19246!GO:0032555;purine ribonucleotide binding;0.0359149485320526;67844,77407,56632,227612,14676,14678,66990,56212,23999,15162,212032,219144!GO:0032553;ribonucleotide binding;0.0359149485320526;67844,77407,56632,227612,14676,14678,66990,56212,23999,15162,212032,219144!GO:0007165;signal transduction;0.0359149485320526;67844,77407,11501,14676,14678,23999,106512,74039,219144,216869,72674,57912,14784,17874,56632,80910,19303,56212,15162,14127,19246!GO:0051090;regulation of transcription factor activity;0.0359149485320526;17874,74039!GO:0046519;sphingoid metabolic process;0.0359149485320526;56632,14421!GO:0033032;regulation of myeloid cell apoptosis;0.0359149485320526;14127!GO:0002720;positive regulation of cytokine production during immune response;0.0359149485320526;14127!GO:0005683;snRNP U7;0.0359149485320526;116748!GO:0033028;myeloid cell apoptosis;0.0359149485320526;14127!GO:0003947;(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity;0.0359149485320526;14421!GO:0046329;negative regulation of JNK cascade;0.0359149485320526;57912!GO:0017050;D-erythro-sphingosine kinase activity;0.0359149485320526;56632!GO:0033025;regulation of mast cell apoptosis;0.0359149485320526;14127!GO:0006669;sphinganine-1-phosphate biosynthetic process;0.0359149485320526;56632!GO:0042989;sequestering of actin monomers;0.0359149485320526;18643!GO:0004796;thromboxane-A synthase activity;0.0359149485320526;21391!GO:0033024;mast cell apoptosis;0.0359149485320526;14127!GO:0033033;negative regulation of myeloid cell apoptosis;0.0359149485320526;14127!GO:0046511;sphinganine biosynthetic process;0.0359149485320526;56632!GO:0050861;positive regulation of B cell receptor signaling pathway;0.0359149485320526;74039!GO:0033026;negative regulation of mast cell apoptosis;0.0359149485320526;14127!GO:0050855;regulation of B cell receptor signaling pathway;0.0359149485320526;74039!GO:0032733;positive regulation of interleukin-10 production;0.0359149485320526;14127!GO:0033023;mast cell homeostasis;0.0359149485320526;14127!GO:0030837;negative regulation of actin filament polymerization;0.0359149485320526;18643!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0359149485320526;14127!GO:0032765;positive regulation of mast cell cytokine production;0.0359149485320526;14127!GO:0002274;myeloid leukocyte activation;0.0370025197063896;20375,14127!GO:0005925;focal adhesion;0.0370025197063896;19303,21894!GO:0017076;purine nucleotide binding;0.0422581447772558;67844,77407,56632,227612,14676,14678,66990,56212,23999,15162,212032,219144!GO:0001817;regulation of cytokine production;0.043598018268161;17874,14127!GO:0007200;G-protein signaling, coupled to IP3 second messenger (phospholipase C activating);0.043598018268161;14676,56632!GO:0000166;nucleotide binding;0.043598018268161;67844,77407,56632,227612,14676,14678,66990,56212,23999,15162,212032,219144!GO:0005924;cell-substrate adherens junction;0.0455388806523591;19303,21894!GO:0009607;response to biotic stimulus;0.0464925092721662;72042,17874,68576,14127!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.0472774236299305;74039,14127!GO:0051050;positive regulation of 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|gostat_on_MCL_coexpression=GO:0007242;intracellular signaling cascade;0.000293664869207983;72674,67844,17874,14784,57912,77407,56632,14676,14678,19303,56212,23999,15162,74039,219144!GO:0030036;actin cytoskeleton organization and biogenesis;0.00402727299685778;56378,18643,56212,21894,19261,12332!GO:0030029;actin filament-based process;0.00402727299685778;56378,18643,56212,21894,19261,12332!GO:0002253;activation of immune response;0.0130000415564871;18636,17874,74039,14127!GO:0003779;actin binding;0.0130000415564871;56378,18643,72042,23999,21894,12332!GO:0008064;regulation of actin polymerization and/or depolymerization;0.0130000415564871;56378,18643,12332!GO:0030832;regulation of actin filament length;0.0130000415564871;56378,18643,12332!GO:0032535;regulation of cellular component size;0.0130000415564871;56378,18643,12332!GO:0032956;regulation of actin cytoskeleton organization and biogenesis;0.0130000415564871;56378,18643,12332!GO:0033043;regulation of organelle organization and biogenesis;0.0130000415564871;56378,18643,12332!GO:0051493;regulation of cytoskeleton organization and biogenesis;0.0130000415564871;56378,18643,12332!GO:0002757;immune response-activating signal transduction;0.0131962910207542;17874,74039,14127!GO:0002764;immune response-regulating signal transduction;0.0131962910207542;17874,74039,14127!GO:0050778;positive regulation of immune response;0.0131962910207542;18636,17874,74039,14127!GO:0002684;positive regulation of immune system process;0.0131962910207542;18636,17874,74039,14127!GO:0032760;positive regulation of tumor necrosis factor production;0.0131962910207542;17874,14127!GO:0008154;actin polymerization and/or depolymerization;0.0131962910207542;56378,18643,12332!GO:0048518;positive regulation of biological process;0.0131962910207542;17874,56632,19261,18636,56212,20354,14127,74039,20375!GO:0032680;regulation of tumor necrosis factor production;0.0173595877607959;17874,14127!GO:0030833;regulation of actin filament polymerization;0.0173595877607959;56378,18643!GO:0050776;regulation of immune response;0.0173595877607959;18636,17874,74039,14127!GO:0002682;regulation of immune system process;0.0177121463524503;18636,17874,74039,14127!GO:0005525;GTP binding;0.0177121463524503;14678,14676,56212,67844,77407,219144!GO:0051240;positive regulation of multicellular organismal process;0.0177121463524503;18636,17874,74039,14127!GO:0007010;cytoskeleton organization and biogenesis;0.0177121463524503;56378,19303,18643,56212,21894,19261,12332!GO:0000165;MAPKKK cascade;0.0177121463524503;19303,17874,14784,57912!GO:0019001;guanyl nucleotide binding;0.0177121463524503;14678,14676,56212,67844,77407,219144!GO:0032561;guanyl ribonucleotide binding;0.0177121463524503;14678,14676,56212,67844,77407,219144!GO:0051128;regulation of cellular component organization and biogenesis;0.0190686644568285;56378,18643,12332!GO:0008092;cytoskeletal protein binding;0.0190686644568285;56378,18643,72042,23999,21894,12332!GO:0007264;small GTPase mediated signal transduction;0.0193338699831508;56212,67844,14784,57912,77407,219144!GO:0009620;response to fungus;0.0195759985896822;72042,17874!GO:0006911;phagocytosis, engulfment;0.0221005852117815;19261,14127!GO:0030148;sphingolipid biosynthetic process;0.0239935659051621;56632,14421!GO:0032640;tumor necrosis factor production;0.0239935659051621;17874,14127!GO:0050764;regulation of phagocytosis;0.0258851381173991;19261,14127!GO:0050766;positive regulation of phagocytosis;0.0258851381173991;19261,14127!GO:0030041;actin filament polymerization;0.028505187330231;56378,18643!GO:0046328;regulation of JNK cascade;0.0311812294906226;17874,57912!GO:0001819;positive regulation of cytokine production;0.0359149485320526;17874,14127!GO:0051091;positive regulation of transcription factor activity;0.0359149485320526;17874,74039!GO:0031252;leading edge;0.0359149485320526;56378,19303,21894!GO:0051707;response to other organism;0.0359149485320526;72042,17874,68576,14127!GO:0045807;positive regulation of endocytosis;0.0359149485320526;19261,14127!GO:0007154;cell communication;0.0359149485320526;67844,77407,11501,17972,14676,14678,23999,106512,74039,219144,216869,72674,57912,14784,17874,56632,80910,19303,56212,15162,14127,19246!GO:0032555;purine ribonucleotide binding;0.0359149485320526;67844,77407,56632,227612,14676,14678,66990,56212,23999,15162,212032,219144!GO:0032553;ribonucleotide binding;0.0359149485320526;67844,77407,56632,227612,14676,14678,66990,56212,23999,15162,212032,219144!GO:0007165;signal transduction;0.0359149485320526;67844,77407,11501,14676,14678,23999,106512,74039,219144,216869,72674,57912,14784,17874,56632,80910,19303,56212,15162,14127,19246!GO:0051090;regulation of transcription factor activity;0.0359149485320526;17874,74039!GO:0046519;sphingoid metabolic process;0.0359149485320526;56632,14421!GO:0033032;regulation of myeloid cell apoptosis;0.0359149485320526;14127!GO:0002720;positive regulation of cytokine production during immune response;0.0359149485320526;14127!GO:0005683;snRNP U7;0.0359149485320526;116748!GO:0033028;myeloid cell apoptosis;0.0359149485320526;14127!GO:0003947;(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity;0.0359149485320526;14421!GO:0046329;negative regulation of JNK cascade;0.0359149485320526;57912!GO:0017050;D-erythro-sphingosine kinase activity;0.0359149485320526;56632!GO:0033025;regulation of mast cell apoptosis;0.0359149485320526;14127!GO:0006669;sphinganine-1-phosphate biosynthetic process;0.0359149485320526;56632!GO:0042989;sequestering of actin monomers;0.0359149485320526;18643!GO:0004796;thromboxane-A synthase activity;0.0359149485320526;21391!GO:0033024;mast cell apoptosis;0.0359149485320526;14127!GO:0033033;negative regulation of myeloid cell apoptosis;0.0359149485320526;14127!GO:0046511;sphinganine biosynthetic process;0.0359149485320526;56632!GO:0050861;positive regulation of B cell receptor signaling pathway;0.0359149485320526;74039!GO:0033026;negative regulation of mast cell apoptosis;0.0359149485320526;14127!GO:0050855;regulation of B cell receptor signaling pathway;0.0359149485320526;74039!GO:0032733;positive regulation of interleukin-10 production;0.0359149485320526;14127!GO:0033023;mast cell homeostasis;0.0359149485320526;14127!GO:0030837;negative regulation of actin filament polymerization;0.0359149485320526;18643!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0359149485320526;14127!GO:0032765;positive regulation of mast cell cytokine production;0.0359149485320526;14127!GO:0002274;myeloid leukocyte activation;0.0370025197063896;20375,14127!GO:0005925;focal adhesion;0.0370025197063896;19303,21894!GO:0017076;purine nucleotide binding;0.0422581447772558;67844,77407,56632,227612,14676,14678,66990,56212,23999,15162,212032,219144!GO:0001817;regulation of cytokine production;0.043598018268161;17874,14127!GO:0007200;G-protein signaling, coupled to IP3 second messenger (phospholipase C activating);0.043598018268161;14676,56632!GO:0000166;nucleotide binding;0.043598018268161;67844,77407,56632,227612,14676,14678,66990,56212,23999,15162,212032,219144!GO:0005924;cell-substrate adherens junction;0.0455388806523591;19303,21894!GO:0009607;response to biotic stimulus;0.0464925092721662;72042,17874,68576,14127!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.0472774236299305;74039,14127!GO:0051050;positive regulation of transport;0.0496110103614133;19261,14127!
}}

Latest revision as of 14:43, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:10277894..10277923,-p3@Rab32
Mm9::chr10:116719318..116719336,-p1@Lyz2
Mm9::chr10:126601827..126601842,+p10@B4galnt1
Mm9::chr10:77008884..77008902,+p@chr10:77008884..77008902
+
Mm9::chr10:79538156..79538198,-p3@Sbno2
Mm9::chr10:80986993..80987004,-p6@Gna15
Mm9::chr10:80987016..80987030,-p2@Gna15
Mm9::chr11:114751586..114751684,+p1@Cd300a
Mm9::chr11:115336959..115337041,+p1@Armc7
Mm9::chr11:115569852..115569928,-p1@Grb2
Mm9::chr11:120493995..120494028,+p@chr11:120493995..120494028
+
Mm9::chr11:70246129..70246209,+p1@Arrb2
Mm9::chr11:70466379..70466416,-p@chr11:70466379..70466416
-
Mm9::chr11:70468102..70468118,-p2@Pfn1
Mm9::chr11:70468126..70468143,-p1@Pfn1
Mm9::chr12:4234123..4234154,+p2@uc007mxq.1
Mm9::chr13:37870307..37870337,+p5@Rreb1
Mm9::chr13:51830052..51830062,-p8@Sema4d
Mm9::chr13:51830064..51830116,-p2@Sema4d
Mm9::chr13:55122557..55122600,-p1@Hk3
Mm9::chr13:95746390..95746407,+p3@Wdr41
Mm9::chr14:61928656..61928692,+p1@Arl11
Mm9::chr14:63456566..63456591,+p2@Wdfy2
Mm9::chr15:100446051..100446108,+p1@Dazap2
p1@Gm2444
Mm9::chr15:103140856..103140875,-p3@Gpr84
Mm9::chr15:103140879..103140907,-p1@Gpr84
Mm9::chr15:78075283..78075296,+p6@Ncf4
Mm9::chr15:78075378..78075436,+p2@Ncf4
Mm9::chr15:82863659..82863670,-p3@Nfam1
Mm9::chr15:82863682..82863704,-p2@Nfam1
Mm9::chr17:34727107..34727150,+p5@Gpsm3
Mm9::chr17:56092051..56092122,+p1@Ebi3
Mm9::chr17:56092151..56092162,+p3@Ebi3
Mm9::chr17:8503966..8504033,+p1@Sft2d1
Mm9::chr19:4125946..4125999,+p1@Tmem134
Mm9::chr1:136311991..136312081,+p1@Adipor1
Mm9::chr1:136312287..136312362,+p2@Adipor1
Mm9::chr1:173164407..173164418,-p2@Fcer1g
Mm9::chr1:173164421..173164455,-p1@Fcer1g
Mm9::chr1:186556410..186556424,-p1@Hlx
Mm9::chr1:74421717..74421746,+p5@Slc11a1
Mm9::chr1:74421782..74421803,+p1@Slc11a1
Mm9::chr2:129418739..129418767,+p5@Sirpa
Mm9::chr2:129418768..129418782,+p11@Sirpa
Mm9::chr2:129418785..129418794,+p15@Sirpa
Mm9::chr2:152934210..152934220,+p2@Hck
Mm9::chr2:167757836..167757879,+p1@Ptpn1
Mm9::chr2:167757883..167757900,+p2@Ptpn1
Mm9::chr2:25052262..25052275,-p3@A830007P12Rik
Mm9::chr2:25052279..25052343,-p1@A830007P12Rik
Mm9::chr2:25278754..25278770,+p2@Fut7
Mm9::chr2:90936886..90936898,+p5@Sfpi1
Mm9::chr2:90936901..90936945,+p1@Sfpi1
Mm9::chr2:90936947..90936977,+p2@Sfpi1
Mm9::chr2:90936978..90937023,+p3@Sfpi1
Mm9::chr2:91826377..91826399,-p@chr2:91826377..91826399
-
Mm9::chr3:107081946..107081976,+p@chr3:107081946..107081976
+
Mm9::chr3:94946268..94946284,-p1@Tnfaip8l2
Mm9::chr3:94946285..94946296,-p2@Tnfaip8l2
Mm9::chr3:95032677..95032754,+p1@Cdc42se1
Mm9::chr4:124373185..124373229,+p@chr4:124373185..124373229
+
Mm9::chr4:124373245..124373258,+p@chr4:124373245..124373258
+
Mm9::chr4:125773954..125773972,+p1@Lsm10
Mm9::chr4:132352276..132352304,-p1@BC013712
Mm9::chr4:133684622..133684685,-p1@Sh3bgrl3
Mm9::chr4:43575059..43575071,-p4@Tln1
Mm9::chr4:61990561..61990594,-p@chr4:61990561..61990594
-
Mm9::chr5:109987976..109988033,-p1@Crlf2
Mm9::chr5:115956677..115956762,+p1@Pxn
Mm9::chr5:116081991..116082042,+p1@Rab35
Mm9::chr5:122841899..122841937,+p1@Arpc3
Mm9::chr5:66543142..66543201,-p4@Rbm47
Mm9::chr6:115626001..115626022,+p2@ENSMUST00000068960
Mm9::chr6:38868968..38868994,+p2@Tbxas1
Mm9::chr6:72499408..72499422,+p3@Capg
Mm9::chr6:72499424..72499472,+p1@Capg
Mm9::chr7:108509764..108509801,+p5@Arap1
Mm9::chr7:109398600..109398637,-p1@Rhog
Mm9::chr7:117916919..117916937,+p15@Ampd3
Mm9::chr7:133843892..133843912,-p@chr7:133843892..133843912
-
Mm9::chr7:147178400..147178419,-p1@Adam8
Mm9::chr7:152469820..152469846,-p1@Tpcn2
Mm9::chr7:16832824..16832828,-p@chr7:16832824..16832828
-
Mm9::chr7:28140963..28140996,-p1@Shkbp1
Mm9::chr7:31198763..31198850,+p1@Tyrobp
Mm9::chr7:52973260..52973288,-p3@Sphk2
Mm9::chr7:87170879..87170914,+p2@Zfp710
Mm9::chr7:89003949..89004011,+p1@Tm6sf1
Mm9::chr8:122364431..122364449,-p1@Cotl1
Mm9::chr8:124956794..124956823,-p1@Cyba
Mm9::chr8:124956824..124956846,-p2@Cyba
Mm9::chr8:59966387..59966402,-p4@Sap30
Mm9::chr8:97094070..97094083,+p@chr8:97094070..97094083
+
Mm9::chr9:106105439..106105502,+p1@Twf2
Mm9::chr9:107537661..107537684,-p1@Gnai2
Mm9::chr9:119249107..119249153,-p1@Myd88
Mm9::chr9:21330588..21330651,+p1@AB124611
Mm9::chr9:65427850..65427868,-p1@Plekho2
Mm9::chrX:20508646..20508660,-p3@Cfp
Mm9::chrX:45806918..45806939,-p@chrX:45806918..45806939
-
Mm9::chrX:7339829..7339855,+p3@Tfe3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0007242intracellular signaling cascade0.000293664869207983
GO:0030036actin cytoskeleton organization and biogenesis0.00402727299685778
GO:0030029actin filament-based process0.00402727299685778
GO:0002253activation of immune response0.0130000415564871
GO:0003779actin binding0.0130000415564871
GO:0008064regulation of actin polymerization and/or depolymerization0.0130000415564871
GO:0030832regulation of actin filament length0.0130000415564871
GO:0032535regulation of cellular component size0.0130000415564871
GO:0032956regulation of actin cytoskeleton organization and biogenesis0.0130000415564871
GO:0033043regulation of organelle organization and biogenesis0.0130000415564871
GO:0051493regulation of cytoskeleton organization and biogenesis0.0130000415564871
GO:0002757immune response-activating signal transduction0.0131962910207542
GO:0002764immune response-regulating signal transduction0.0131962910207542
GO:0050778positive regulation of immune response0.0131962910207542
GO:0002684positive regulation of immune system process0.0131962910207542
GO:0032760positive regulation of tumor necrosis factor production0.0131962910207542
GO:0008154actin polymerization and/or depolymerization0.0131962910207542
GO:0048518positive regulation of biological process0.0131962910207542
GO:0032680regulation of tumor necrosis factor production0.0173595877607959
GO:0030833regulation of actin filament polymerization0.0173595877607959
GO:0050776regulation of immune response0.0173595877607959
GO:0002682regulation of immune system process0.0177121463524503
GO:0005525GTP binding0.0177121463524503
GO:0051240positive regulation of multicellular organismal process0.0177121463524503
GO:0007010cytoskeleton organization and biogenesis0.0177121463524503
GO:0000165MAPKKK cascade0.0177121463524503
GO:0019001guanyl nucleotide binding0.0177121463524503
GO:0032561guanyl ribonucleotide binding0.0177121463524503
GO:0051128regulation of cellular component organization and biogenesis0.0190686644568285
GO:0008092cytoskeletal protein binding0.0190686644568285
GO:0007264small GTPase mediated signal transduction0.0193338699831508
GO:0009620response to fungus0.0195759985896822
GO:0006911phagocytosis, engulfment0.0221005852117815
GO:0030148sphingolipid biosynthetic process0.0239935659051621
GO:0032640tumor necrosis factor production0.0239935659051621
GO:0050764regulation of phagocytosis0.0258851381173991
GO:0050766positive regulation of phagocytosis0.0258851381173991
GO:0030041actin filament polymerization0.028505187330231
GO:0046328regulation of JNK cascade0.0311812294906226
GO:0001819positive regulation of cytokine production0.0359149485320526
GO:0051091positive regulation of transcription factor activity0.0359149485320526
GO:0031252leading edge0.0359149485320526
GO:0051707response to other organism0.0359149485320526
GO:0045807positive regulation of endocytosis0.0359149485320526
GO:0007154cell communication0.0359149485320526
GO:0032555purine ribonucleotide binding0.0359149485320526
GO:0032553ribonucleotide binding0.0359149485320526
GO:0007165signal transduction0.0359149485320526
GO:0051090regulation of transcription factor activity0.0359149485320526
GO:0046519sphingoid metabolic process0.0359149485320526
GO:0033032regulation of myeloid cell apoptosis0.0359149485320526
GO:0002720positive regulation of cytokine production during immune response0.0359149485320526
GO:0005683snRNP U70.0359149485320526
GO:0033028myeloid cell apoptosis0.0359149485320526
GO:0003947(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity0.0359149485320526
GO:0046329negative regulation of JNK cascade0.0359149485320526
GO:0017050D-erythro-sphingosine kinase activity0.0359149485320526
GO:0033025regulation of mast cell apoptosis0.0359149485320526
GO:0006669sphinganine-1-phosphate biosynthetic process0.0359149485320526
GO:0042989sequestering of actin monomers0.0359149485320526
GO:0004796thromboxane-A synthase activity0.0359149485320526
GO:0033024mast cell apoptosis0.0359149485320526
GO:0033033negative regulation of myeloid cell apoptosis0.0359149485320526
GO:0046511sphinganine biosynthetic process0.0359149485320526
GO:0050861positive regulation of B cell receptor signaling pathway0.0359149485320526
GO:0033026negative regulation of mast cell apoptosis0.0359149485320526
GO:0050855regulation of B cell receptor signaling pathway0.0359149485320526
GO:0032733positive regulation of interleukin-10 production0.0359149485320526
GO:0033023mast cell homeostasis0.0359149485320526
GO:0030837negative regulation of actin filament polymerization0.0359149485320526
GO:0002431Fc receptor mediated stimulatory signaling pathway0.0359149485320526
GO:0032765positive regulation of mast cell cytokine production0.0359149485320526
GO:0002274myeloid leukocyte activation0.0370025197063896
GO:0005925focal adhesion0.0370025197063896
GO:0017076purine nucleotide binding0.0422581447772558
GO:0001817regulation of cytokine production0.043598018268161
GO:0007200G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)0.043598018268161
GO:0000166nucleotide binding0.043598018268161
GO:0005924cell-substrate adherens junction0.0455388806523591
GO:0009607response to biotic stimulus0.0464925092721662
GO:0002429immune response-activating cell surface receptor signaling pathway0.0472774236299305
GO:0051050positive regulation of transport0.0496110103614133



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
musculoskeletal system5.15e-1132
hemolymphoid system1.27e-1048
immune system1.27e-1048
bone marrow1.81e-1016
bone element8.64e-1022
skeletal element8.64e-1022
skeletal system8.64e-1022
hematopoietic system1.86e-0945
blood island1.86e-0945


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.11.40054
MA0004.10.0325973
MA0006.10.301455
MA0007.10.251353
MA0009.10.0760193
MA0014.12.07823
MA0017.10.0265679
MA0019.10.0246345
MA0024.10.0605358
MA0025.10.190261
MA0027.11.42396
MA0028.12.11679
MA0029.10.0535917
MA0030.10.449417
MA0031.10.172023
MA0038.10.265576
MA0040.10.276429
MA0041.10.0110162
MA0042.10.00878609
MA0043.11.23229
MA0046.10.302305
MA0048.11.3463
MA0050.10.576853
MA0051.10.280739
MA0052.10.285221
MA0055.10.0226942
MA0056.10
MA0057.10.227226
MA0058.10.0235584
MA0059.10.0285114
MA0060.10.530516
MA0061.11.35832
MA0063.10
MA0066.10.118522
MA0067.10.260898
MA0068.10.25091
MA0069.10.285594
MA0070.10.0803074
MA0071.10.573844
MA0072.10.95315
MA0073.11.4424
MA0074.10.347445
MA0076.11.92097
MA0077.10.069079
MA0078.10.013734
MA0081.12.68139
MA0083.10.116791
MA0084.10.512075
MA0087.10.0973326
MA0088.10.620206
MA0089.10
MA0090.10.341492
MA0091.10.0381275
MA0092.10.342381
MA0093.10.00867738
MA0095.10
MA0098.10
MA0100.10.0802299
MA0101.11.48835
MA0103.10.123783
MA0105.11.87577
MA0106.10.180373
MA0107.11.7571
MA0108.20.0292197
MA0109.10
MA0111.10.240493
MA0113.10.30279
MA0114.10.220785
MA0115.10.118493
MA0116.13.72943
MA0117.10.338498
MA0119.10.368226
MA0122.10.112659
MA0124.10.225924
MA0125.10.180743
MA0130.10
MA0131.10.760842
MA0132.10
MA0133.10
MA0135.10.135021
MA0136.12.88686
MA0139.11.06162
MA0140.10.32192
MA0141.10.534974
MA0142.10.041167
MA0143.10.0630512
MA0144.10.0549285
MA0145.12.75425
MA0146.13.2162
MA0147.10.383516
MA0148.10.0114641
MA0149.10.149383
MA0062.27.00423
MA0035.20.0835473
MA0039.29.99365
MA0138.21.07985
MA0002.20.357703
MA0137.20.0418654
MA0104.20.569335
MA0047.20.0458653
MA0112.22.51929
MA0065.20.436136
MA0150.10.397609
MA0151.10
MA0152.10.128029
MA0153.10.868113
MA0154.11.30481
MA0155.11.30184
MA0156.12.95631
MA0157.10.134293
MA0158.10
MA0159.12.20589
MA0160.10.194668
MA0161.10
MA0162.10.780892
MA0163.13.11739
MA0164.11.20971
MA0080.25.29028
MA0018.20.238052
MA0099.20.093086
MA0079.27.78223
MA0102.21.36958
MA0258.11.90584
MA0259.10.599221
MA0442.10