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UBERON:0002371

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Name:bone marrow
Namespace:FANTOM
Definition:"flexible tissue found in the hollow interior of bones. In adults, marrow in large bones produces new blood cells[WP]." [Wikipedia:Bone_marrow]
Xrefs:
links:

AAO:0011007
BTO:0000141
BTO:0000829
EFO:0000868
EV:0100046
FMA:9608
GAID:1287
galen:BoneMarrow
[1]
MA:0000134
MAT:0000084
MESH:A.15.382.216
MIAA:0000084
ncithesaurus:Bone_Marrow
OpenCyc:Mx4rvVm-FpwpEbGdrcN5Y29ycA
SCTID:421320006
VHOG:0001218

XAO:0000123
Synonyms: "anterior kidney" RELATED []
"head kidney" BROAD []
"kidney marrow" RELATED []
"medulla of bone" RELATED [BTO:0000141]
"medulla ossea" EXACT []
"medulla ossium" RELATED LATIN [Wikipedia:Bone_marrow]
"medulla ossium" RELATED [BTO:0000141]
Comments:TODO - create superclass for bone marrow / head kidney. both are portions of tissue in the hematopoetic system. also consider adding as subclass of zone of bone organ for consistency with FMA. See also: Leydig and epigonal organs
Alt_id: UBERON:FMA_9608-MA_0000134-MIAA_0000084-XAO_0000123-ZFA_0000669
Subset: uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0012429(hemopoietic tissue)
part_of:UBERON:0001474(bone element),UBERON:0002390(hematopoietic system),UBERON:0002405(immune system)



Children

derives from:FF:0010192 (human bone marrow - adult sample),FF:0200020 (osteoclast, bone marrow-derived sample),FF:0200029 (hematopoietic stem cell, bone marrow derived sample)
part of:CL:0000556 (megakaryocyte),CL:0000557 (granulocyte monocyte progenitor cell),CL:0002092 (bone marrow cell),CL:0002476 (bone marrow macrophage),CL:0002540 (mesenchymal stem cell of the bone marrow),UBERON:0007195 (stroma of bone marrow),CL:1001610 (bone marrow hematopoietic cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002371 (bone marrow), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data