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{{UBERON
{{UBERON
|id=UBERON:0007100
|name=circulatory organ
|namespace=
|def="A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood[GO]." [GO:0007507]
|xref=ANISEED:1235302;;FBbt:00003154;;http://www.sciencemag.org/content/313/5795/1922/F1.large.jpg;;TADS:0000147
|is_a=UBERON:0003103
|synonym="adult heart" RELATED [FBbt:00003154];;"cardiac structure" EXACT [];;"dorsal tube" NARROW [Wikipedia:Heart];;"heart" NARROW [GO:0007507];;"heart or heart like organ" EXACT []
|comment=editor note: we need to find the appropriate GO process to use for the definition - 'blood circulation' may not apply to invertebrates; 'circulatory system process' is circular. Note we cannot use a part_of-based definition as this results in the iris and all vascular elements being categorized as circulatory organs. Taxon notes: note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. "The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian". Amniotes:  four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis
|alt_id=
|alt_id=
|disjoint_from=
|comment=editor note: we need to find the appropriate GO process to use for the definition - 'blood circulation' may not apply to invertebrates; 'circulatory system process' is circular. Note we cannot use a part_of-based definition as this results in the iris and all vascular elements being categorized as circulatory organs. Taxon notes: note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. "The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian". Amniotes:  four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis. Gene notes: Bmp, Nkx, Gata
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood[GO]." [GO:0007507]
|subset=grouping_class
|adjacent_to=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=
|has_quality=
|has_quality=
|id=UBERON:0007100
|is_a=UBERON:0015228
|is_obsolete=
|located_in=
|located_in=
|name=primary circulatory organ
|namespace=FANTOM
|obo_creation_date=
|part_of=UBERON:0001009
|part_of=UBERON:0001009
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.obo.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;"present_in_taxon" NCBITaxon:7718
|subset=grouping_class
|synonym="adult heart" RELATED [FBbt:00003154];;"cardiac pump" EXACT [];;"cardiac structure" RELATED [];;"dorsal tube" NARROW [Wikipedia:Heart];;"heart" NARROW [GO:0007507];;"heart or heart like organ" EXACT []
|union_of=
|xref=ANISEED:1235302;;FBbt:00003154;;http://www.sciencemag.org/content/313/5795/1922/F1.large.jpg;;TADS:0000147
}}
}}

Latest revision as of 18:00, 12 September 2014

Name:primary circulatory organ
Namespace:FANTOM
Definition:"A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood[GO]." [GO:0007507]
Xrefs:
links:

ANISEED:1235302
FBbt:00003154
[1]

TADS:0000147
Synonyms: "adult heart" RELATED [FBbt:00003154]
"cardiac pump" EXACT []
"cardiac structure" RELATED []
"dorsal tube" NARROW [Wikipedia:Heart]
"heart" NARROW [GO:0007507]
"heart or heart like organ" EXACT []
Comments:editor note: we need to find the appropriate GO process to use for the definition - 'blood circulation' may not apply to invertebrates; 'circulatory system process' is circular. Note we cannot use a part_of-based definition as this results in the iris and all vascular elements being categorized as circulatory organs. Taxon notes: note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. "The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian". Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis. Gene notes: Bmp, Nkx, Gata
Subset: grouping_class

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0015228(circulatory organ)
part_of:UBERON:0001009(circulatory system)



Children

is a:UBERON:0000948 (heart)
part of:CL:0000746 (cardiac muscle cell),CL:0002494 (cardiocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0007100 (primary circulatory organ), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.09e-81FFCP PHASE1:Mm9::chr4:147375434..147375447,+#_51964097263442c9eecfc750d638af3ep@chr4:147375434..147375447, +
1.09e-81FFCP PHASE1:Mm9::chr9:24549775..24549776,-#_51964097263442c9eecfc750d638af3ep@chr9:24549775..24549776, -
1.09e-81FFCP PHASE2:Mm9::chr4:147375434..147375447,+#_51964097263442c9eecfc750d638af3ep@chr4:147375434..147375447, +
1.09e-81FFCP PHASE1:Mm9::chr1:137747392..137747402,-#_51964097263442c9eecfc750d638af3ep@chr1:137747392..137747402, -
1.09e-81FFCP PHASE2:Mm9::chr1:137747392..137747402,-#_51964097263442c9eecfc750d638af3ep@chr1:137747392..137747402, -
1.09e-81FFCP PHASE2:Mm9::chr9:24549775..24549776,-#_51964097263442c9eecfc750d638af3ep@chr9:24549775..24549776, -
5.69e-81FFCP PHASE1:Hg19::chr17:77019002..77019027,+#_653e72ab25b5d33370f1abf2903c44fdp@chr17:77019002..77019027, +
5.69e-81FFCP PHASE2:Hg19::chr17:77019002..77019027,+#_653e72ab25b5d33370f1abf2903c44fdp@chr17:77019002..77019027, +
2.21e-79FFCP PHASE1:Hg19::chr17:77018953..77018966,+#_10881b560d1ebe029bb42fde521acc61p@chr17:77018953..77018966, +
2.21e-79FFCP PHASE2:Hg19::chr17:77018953..77018966,+#_10881b560d1ebe029bb42fde521acc61p@chr17:77018953..77018966, +
1.88e-78FFCP PHASE2:Mm9::chr4:140980456..140980463,+#_a6e8a2c1f45de514e93b752b8ba5f4ecp@chr4:140980456..140980463, +
1.88e-78FFCP PHASE1:Mm9::chr4:140980456..140980463,+#_a6e8a2c1f45de514e93b752b8ba5f4ecp@chr4:140980456..140980463, +
1.92e-77FFCP PHASE2:Mm9::chr1:137737483..137737497,-#_77d4c4d9af3217b9c97dce7da1dc578cp@chr1:137737483..137737497, -
1.92e-77FFCP PHASE1:Mm9::chr12:113728951..113728965,+#_77d4c4d9af3217b9c97dce7da1dc578cp@chr12:113728951..113728965, +
1.92e-77FFCP PHASE2:Mm9::chr12:113728951..113728965,+#_77d4c4d9af3217b9c97dce7da1dc578cp@chr12:113728951..113728965, +
1.92e-77FFCP PHASE1:Mm9::chr1:137737483..137737497,-#_77d4c4d9af3217b9c97dce7da1dc578cp@chr1:137737483..137737497, -
2.14e-77FFCP PHASE1:Mm9::chr19:36187511..36187515,-#_8b0f994f15e8a19d643bd690f0d14ce7p@chr19:36187511..36187515, -
2.14e-77FFCP PHASE1:Mm9::chr4:147375200..147375220,+#_8b0f994f15e8a19d643bd690f0d14ce7p@chr4:147375200..147375220, +
2.14e-77FFCP PHASE2:Mm9::chr4:147375200..147375220,+#_8b0f994f15e8a19d643bd690f0d14ce7p@chr4:147375200..147375220, +
2.14e-77FFCP PHASE2:Mm9::chr19:36187511..36187515,-#_8b0f994f15e8a19d643bd690f0d14ce7p@chr19:36187511..36187515, -
8.14e-77FFCP PHASE2:Mm9::chr1:137747382..137747385,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137747382..137747385, -
8.14e-77FFCP PHASE1:Mm9::chr14:55584663..55584731,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55584663..55584731, -
8.14e-77FFCP PHASE2:Mm9::chr14:55579265..55579297,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55579265..55579297, -
8.14e-77FFCP PHASE1:Mm9::chr1:137744668..137744681,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744668..137744681, -
8.14e-77FFCP PHASE2:Mm9::chr14:55568737..55568746,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55568737..55568746, -
8.14e-77FFCP PHASE2:Mm9::chr1:137744611..137744621,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744611..137744621, +
8.14e-77FFCP PHASE1:Mm9::chr1:137744636..137744654,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744636..137744654, +
8.14e-77FFCP PHASE1:Mm9::chr1:137744550..137744565,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744550..137744565, +
8.14e-77FFCP PHASE2:Mm9::chr1:137744636..137744654,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744636..137744654, +
8.14e-77FFCP PHASE2:Mm9::chr1:137744550..137744565,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744550..137744565, +
8.14e-77FFCP PHASE2:Mm9::chr14:55571909..55571953,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55571909..55571953, -
8.14e-77FFCP PHASE1:Mm9::chr1:137747953..137747967,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137747953..137747967, -
8.14e-77FFCP PHASE1:Mm9::chr14:55584197..55584239,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55584197..55584239, -
8.14e-77FFCP PHASE1:Mm9::chr15:88850827..88850850,+#_0ebbd06366a73ebcea0f8bc6cb089866p2@Mov10l1
8.14e-77FFCP PHASE1:Mm9::chr1:137745434..137745445,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137745434..137745445, +
8.14e-77FFCP PHASE2:Mm9::chr1:137743272..137743307,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137743272..137743307, +
8.14e-77FFCP PHASE2:Mm9::chr14:55584272..55584298,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55584272..55584298, -
8.14e-77FFCP PHASE2:Mm9::chr14:55584663..55584731,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55584663..55584731, -
8.14e-77FFCP PHASE1:Mm9::chr1:137743272..137743307,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137743272..137743307, +
8.14e-77FFCP PHASE1:Mm9::chr14:55565785..55565833,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55565785..55565833, -
8.14e-77FFCP PHASE1:Mm9::chr14:55568790..55568803,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55568790..55568803, -
8.14e-77FFCP PHASE2:Mm9::chr1:137745434..137745445,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137745434..137745445, +
8.14e-77FFCP PHASE2:Mm9::chr1:137744668..137744681,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744668..137744681, -
8.14e-77FFCP PHASE1:Mm9::chr14:55571909..55571953,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55571909..55571953, -
8.14e-77FFCP PHASE1:Mm9::chr14:55568737..55568746,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55568737..55568746, -
8.14e-77FFCP PHASE2:Mm9::chr4:147375901..147375913,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr4:147375901..147375913, +
8.14e-77FFCP PHASE2:Mm9::chr1:137744333..137744352,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744333..137744352, -
8.14e-77FFCP PHASE2:Mm9::chr14:55572120..55572173,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55572120..55572173, +
8.14e-77FFCP PHASE1:Mm9::chr4:147375901..147375913,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr4:147375901..147375913, +
8.14e-77FFCP PHASE1:Mm9::chr14:55586837..55586880,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55586837..55586880, -
8.14e-77FFCP PHASE1:Mm9::chr1:137744611..137744621,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744611..137744621, +
8.14e-77FFCP PHASE2:Mm9::chr14:55565785..55565833,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55565785..55565833, -
8.14e-77FFCP PHASE1:Mm9::chr1:137747289..137747313,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137747289..137747313, +
8.14e-77FFCP PHASE1:Mm9::chr19:36193772..36193793,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr19:36193772..36193793, -
8.14e-77FFCP PHASE1:Mm9::chr14:55568937..55568988,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55568937..55568988, -
8.14e-77FFCP PHASE2:Mm9::chr5:120286706..120286736,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr5:120286706..120286736, +
8.14e-77FFCP PHASE2:Mm9::chr1:137747289..137747313,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137747289..137747313, +
8.14e-77FFCP PHASE1:Mm9::chr14:55584272..55584298,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55584272..55584298, -
8.14e-77FFCP PHASE1:Mm9::chr1:137747382..137747385,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137747382..137747385, -
8.14e-77FFCP PHASE1:Mm9::chr14:55581579..55581620,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55581579..55581620, -
8.14e-77FFCP PHASE1:Mm9::chr1:137744333..137744352,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744333..137744352, -
8.14e-77FFCP PHASE2:Mm9::chr14:55586837..55586880,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55586837..55586880, -
8.14e-77FFCP PHASE1:Mm9::chr11:58815923..58815951,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr11:58815923..58815951, -
8.14e-77FFCP PHASE2:Mm9::chr11:58815923..58815951,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr11:58815923..58815951, -
8.14e-77FFCP PHASE2:Mm9::chr1:137747953..137747967,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137747953..137747967, -
8.14e-77FFCP PHASE2:Mm9::chr14:55568937..55568988,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55568937..55568988, -
8.14e-77FFCP PHASE1:Mm9::chr5:120286706..120286736,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr5:120286706..120286736, +
8.14e-77FFCP PHASE2:Mm9::chr11:65461897..65461929,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr11:65461897..65461929, -
8.14e-77FFCP PHASE2:Mm9::chr14:55584197..55584239,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55584197..55584239, -
8.14e-77FFCP PHASE1:Mm9::chr14:55579265..55579297,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55579265..55579297, -
8.14e-77FFCP PHASE1:Mm9::chr14:55572120..55572173,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55572120..55572173, +
8.14e-77FFCP PHASE2:Mm9::chr19:36193772..36193793,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr19:36193772..36193793, -
8.14e-77FFCP PHASE1:Mm9::chr11:65461897..65461929,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr11:65461897..65461929, -
8.14e-77FFCP PHASE2:Mm9::chr15:88850827..88850850,+#_0ebbd06366a73ebcea0f8bc6cb089866p2@Mov10l1
8.14e-77FFCP PHASE2:Mm9::chr14:55563577..55563611,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55563577..55563611, -
8.14e-77FFCP PHASE2:Mm9::chr14:55568790..55568803,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55568790..55568803, -
8.14e-77FFCP PHASE2:Mm9::chr14:55581579..55581620,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55581579..55581620, -
8.14e-77FFCP PHASE1:Mm9::chr14:55563577..55563611,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55563577..55563611, -
1.2e-73FFCP PHASE2:Mm9::chr1:137742152..137742184,-#_fe40d489e19641fa791cef9be436ab32p@chr1:137742152..137742184, -
1.2e-73FFCP PHASE1:Mm9::chr1:137742152..137742184,-#_fe40d489e19641fa791cef9be436ab32p@chr1:137742152..137742184, -
1.46e-72FFCP PHASE1:Mm9::chr1:137742470..137742481,+#_465d556be13caa16245407d1aa2d5e38p@chr1:137742470..137742481, +
1.46e-72FFCP PHASE1:Mm9::chr16:5431481..5431510,+#_465d556be13caa16245407d1aa2d5e38p@chr16:5431481..5431510, +
1.46e-72FFCP PHASE2:Mm9::chr1:137742470..137742481,+#_465d556be13caa16245407d1aa2d5e38p@chr1:137742470..137742481, +
1.46e-72FFCP PHASE2:Mm9::chr16:5431481..5431510,+#_465d556be13caa16245407d1aa2d5e38p@chr16:5431481..5431510, +
1.46e-72FFCP PHASE2:Mm9::chr14:55577329..55577367,-#_465d556be13caa16245407d1aa2d5e38p@chr14:55577329..55577367, -
1.46e-72FFCP PHASE1:Mm9::chr14:55577329..55577367,-#_465d556be13caa16245407d1aa2d5e38p@chr14:55577329..55577367, -
1.46e-72FFCP PHASE1:Mm9::chr7:4473478..4473505,-#_465d556be13caa16245407d1aa2d5e38p2@Tnni3
1.46e-72FFCP PHASE2:Mm9::chr7:4473478..4473505,-#_465d556be13caa16245407d1aa2d5e38p2@Tnni3
1.63e-72FFCP PHASE1:Mm9::chr2:113880065..113880076,+#_60735c988619e5db959bc6655406d1ecp1@ENSMUST00000154140
1.63e-72FFCP PHASE2:Mm9::chr5:58108164..58108178,+#_60735c988619e5db959bc6655406d1ecp@chr5:58108164..58108178, +
1.63e-72FFCP PHASE2:Mm9::chr2:17382210..17382221,-#_60735c988619e5db959bc6655406d1ecp5@Nebl
1.63e-72FFCP PHASE1:Mm9::chr5:58108164..58108178,+#_60735c988619e5db959bc6655406d1ecp@chr5:58108164..58108178, +
1.63e-72FFCP PHASE1:Mm9::chr2:17382210..17382221,-#_60735c988619e5db959bc6655406d1ecp5@Nebl
1.63e-72FFCP PHASE1:Mm9::chr19:36193739..36193752,-#_60735c988619e5db959bc6655406d1ecp@chr19:36193739..36193752, -
1.63e-72FFCP PHASE2:Mm9::chr10:53062244..53062249,+#_60735c988619e5db959bc6655406d1ecp@chr10:53062244..53062249, +
1.63e-72FFCP PHASE2:Mm9::chr19:36193739..36193752,-#_60735c988619e5db959bc6655406d1ecp@chr19:36193739..36193752, -
1.63e-72FFCP PHASE1:Mm9::chr16:38713504..38713520,-#_60735c988619e5db959bc6655406d1ecp11@Arhgap31
1.63e-72FFCP PHASE2:Mm9::chr16:38713504..38713520,-#_60735c988619e5db959bc6655406d1ecp11@Arhgap31
1.63e-72FFCP PHASE2:Mm9::chr2:113880065..113880076,+#_60735c988619e5db959bc6655406d1ecp1@ENSMUST00000154140
1.63e-72FFCP PHASE1:Mm9::chr10:53062244..53062249,+#_60735c988619e5db959bc6655406d1ecp@chr10:53062244..53062249, +

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