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|gostat_on_coexpression_clusters=GO:0050665!hydrogen peroxide biosynthetic process!0.0038853240511488!53905$GO:0042335!cuticle development!0.0038853240511488!53905$GO:0016174!NAD(P)H oxidase activity!0.0038853240511488!53905$GO:0042554!superoxide release!0.0038853240511488!53905$GO:0050664!oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor!0.0038853240511488!53905$GO:0051591!response to cAMP!0.00631290812271665!53905$GO:0042744!hydrogen peroxide catabolic process!0.00631290812271665!53905$GO:0042743!hydrogen peroxide metabolic process!0.00631290812271665!53905$GO:0042542!response to hydrogen peroxide!0.00815725894822441!53905$GO:0006801!superoxide metabolic process!0.00815725894822441!53905$GO:0000302!response to reactive oxygen species!0.00953361626905974!53905$GO:0050661!NADP binding!0.0116491094420604!53905$GO:0042446!hormone biosynthetic process!0.0116491094420604!53905$GO:0019221!cytokine and chemokine mediated signaling pathway!0.0116491094420604!53905$GO:0006800!oxygen and reactive oxygen species metabolic process!0.0116491094420604!53905$GO:0010033!response to organic substance!0.0138924756148232!53905$GO:0004601!peroxidase activity!0.0138924756148232!53905$GO:0016684!oxidoreductase activity, acting on peroxide as acceptor!0.0138924756148232!53905$GO:0016324!apical plasma membrane!0.0138924756148232!53905$GO:0045177!apical part of cell!0.016261466958797!53905$GO:0042445!hormone metabolic process!0.016261466958797!53905$GO:0016651!oxidoreductase activity, acting on NADH or NADPH!0.0190444920081179!53905$GO:0050660!FAD binding!0.0192267960029108!53905$GO:0006979!response to oxidative stress!0.019393736430353!53905$GO:0050662!coenzyme binding!0.0416988764963919!53905$GO:0020037!heme binding!0.0416988764963919!53905$GO:0046906!tetrapyrrole binding!0.0416988764963919!53905
|gostat_on_coexpression_clusters=GO:0050665!hydrogen peroxide biosynthetic process!0.0038853240511488!53905$GO:0042335!cuticle development!0.0038853240511488!53905$GO:0016174!NAD(P)H oxidase activity!0.0038853240511488!53905$GO:0042554!superoxide release!0.0038853240511488!53905$GO:0050664!oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor!0.0038853240511488!53905$GO:0051591!response to cAMP!0.00631290812271665!53905$GO:0042744!hydrogen peroxide catabolic process!0.00631290812271665!53905$GO:0042743!hydrogen peroxide metabolic process!0.00631290812271665!53905$GO:0042542!response to hydrogen peroxide!0.00815725894822441!53905$GO:0006801!superoxide metabolic process!0.00815725894822441!53905$GO:0000302!response to reactive oxygen species!0.00953361626905974!53905$GO:0050661!NADP binding!0.0116491094420604!53905$GO:0042446!hormone biosynthetic process!0.0116491094420604!53905$GO:0019221!cytokine and chemokine mediated signaling pathway!0.0116491094420604!53905$GO:0006800!oxygen and reactive oxygen species metabolic process!0.0116491094420604!53905$GO:0010033!response to organic substance!0.0138924756148232!53905$GO:0004601!peroxidase activity!0.0138924756148232!53905$GO:0016684!oxidoreductase activity, acting on peroxide as acceptor!0.0138924756148232!53905$GO:0016324!apical plasma membrane!0.0138924756148232!53905$GO:0045177!apical part of cell!0.016261466958797!53905$GO:0042445!hormone metabolic process!0.016261466958797!53905$GO:0016651!oxidoreductase activity, acting on NADH or NADPH!0.0190444920081179!53905$GO:0050660!FAD binding!0.0192267960029108!53905$GO:0006979!response to oxidative stress!0.019393736430353!53905$GO:0050662!coenzyme binding!0.0416988764963919!53905$GO:0020037!heme binding!0.0416988764963919!53905$GO:0046906!tetrapyrrole binding!0.0416988764963919!53905
|id=C2335
|id=C2335
|ontology_enrichment_celltype=CL:0002076!3.61e-08!43;CL:0002368!3.67e-08!13
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!1.45e-23!115;UBERON:0000165!3.63e-12!28;UBERON:0000930!3.63e-12!28;UBERON:0000924!5.72e-12!173;UBERON:0006601!5.72e-12!173;UBERON:0004119!3.53e-11!169;UBERON:0000925!3.53e-11!169;UBERON:0006595!3.53e-11!169;UBERON:0004121!3.90e-11!169;UBERON:0003102!5.13e-10!95;UBERON:0000153!1.18e-09!129;UBERON:0007811!1.18e-09!129;UBERON:0000166!1.74e-09!21;UBERON:0000161!2.63e-09!35;UBERON:0000078!4.61e-09!18;UBERON:0001004!8.48e-09!72;UBERON:0000033!1.34e-08!123;UBERON:0000062!2.08e-08!511;UBERON:0000468!1.62e-07!659;UBERON:0005631!2.96e-07!14;UBERON:0000158!2.96e-07!14
}}
}}

Revision as of 14:22, 21 May 2012


Full id: C2335_lung_immature_thyroid_salivary_esophagus_ductus_tongue



Phase1 CAGE Peaks

Hg19::chr15:45422041..45422052,-p2@DUOXA1
Hg19::chr15:45422056..45422086,-p1@DUOXA1
Hg19::chr15:45422163..45422172,+p2@DUOX1
Hg19::chr15:45422178..45422201,+p1@DUOX1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0050665hydrogen peroxide biosynthetic process0.0038853240511488
GO:0042335cuticle development0.0038853240511488
GO:0016174NAD(P)H oxidase activity0.0038853240511488
GO:0042554superoxide release0.0038853240511488
GO:0050664oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor0.0038853240511488
GO:0051591response to cAMP0.00631290812271665
GO:0042744hydrogen peroxide catabolic process0.00631290812271665
GO:0042743hydrogen peroxide metabolic process0.00631290812271665
GO:0042542response to hydrogen peroxide0.00815725894822441
GO:0006801superoxide metabolic process0.00815725894822441
GO:0000302response to reactive oxygen species0.00953361626905974
GO:0050661NADP binding0.0116491094420604
GO:0042446hormone biosynthetic process0.0116491094420604
GO:0019221cytokine and chemokine mediated signaling pathway0.0116491094420604
GO:0006800oxygen and reactive oxygen species metabolic process0.0116491094420604
GO:0010033response to organic substance0.0138924756148232
GO:0004601peroxidase activity0.0138924756148232
GO:0016684oxidoreductase activity, acting on peroxide as acceptor0.0138924756148232
GO:0016324apical plasma membrane0.0138924756148232
GO:0045177apical part of cell0.016261466958797
GO:0042445hormone metabolic process0.016261466958797
GO:0016651oxidoreductase activity, acting on NADH or NADPH0.0190444920081179
GO:0050660FAD binding0.0192267960029108
GO:0006979response to oxidative stress0.019393736430353
GO:0050662coenzyme binding0.0416988764963919
GO:0020037heme binding0.0416988764963919
GO:0046906tetrapyrrole binding0.0416988764963919



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
endo-epithelial cell3.61e-0843
respiratory epithelial cell3.67e-0813
Uber Anatomy
Ontology termp-valuen
adult organism1.45e-23115
mouth3.63e-1228
stomodeum3.63e-1228
ectoderm5.72e-12173
presumptive ectoderm5.72e-12173
endoderm-derived structure3.53e-11169
endoderm3.53e-11169
presumptive endoderm3.53e-11169
ectoderm-derived structure3.90e-11169
surface structure5.13e-1095
anterior region of body1.18e-09129
craniocervical region1.18e-09129
oral opening1.74e-0921
orifice2.63e-0935
mixed ectoderm/mesoderm/endoderm-derived structure4.61e-0918
respiratory system8.48e-0972
head1.34e-08123
organ2.08e-08511
multi-cellular organism1.62e-07659
extraembryonic membrane2.96e-0714
membranous layer2.96e-0714


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.