CL:0000556: Difference between revisions
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|id=CL:0000556 | |id=CL:0000556 | ||
|name=megakaryocyte | |name=megakaryocyte | ||
|namespace=efo | |namespace=cell;;efo | ||
|def="A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm." [ISBN:0721601464, MESH:D008533] | |def="A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm." [ISBN:0721601464, MESH:D008533] | ||
|xref=BTO:0000843;;FMA:83555 | |xref=BTO:0000843;;FMA:83555 | ||
|is_a= | |is_a=CL:0000763 | ||
|synonym="megacaryocyte" EXACT [];;"megalocaryocyte" EXACT [];;"megalokaryocyte" EXACT [] | |synonym="megacaryocyte" EXACT [];;"megalocaryocyte" EXACT [];;"megalokaryocyte" EXACT [] | ||
|comment=Megakaryocytes are reportedly CD181-positive and CD182-positive. | |comment=Megakaryocytes are reportedly CD181-positive and CD182-positive. | ||
| Line 14: | Line 14: | ||
|obo_creation_date= | |obo_creation_date= | ||
|subset= | |subset= | ||
|derives_from= | |derives_from= | ||
|develops_from= | |develops_from= | ||
|has_quality= | |has_quality= | ||
|located_in= | |located_in= | ||
|part_of= | |part_of= | ||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon | |property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl | ||
|is_obsolete= | |is_obsolete= | ||
|preceded_by= | |preceded_by= | ||
}} | }} | ||
Revision as of 17:25, 26 June 2012
| Name: | megakaryocyte | ||
|---|---|---|---|
| Namespace: | cell;;efo | ||
| Definition: | "A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm." [ISBN:0721601464, MESH:D008533] | ||
| Xrefs: |
| ||
| Synonyms: |
"megacaryocyte" EXACT [] "megalocaryocyte" EXACT [] "megalokaryocyte" EXACT [] | ||
| Comments: | Megakaryocytes are reportedly CD181-positive and CD182-positive. |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | CL:0000763(myeloid cell) |
|---|---|
| disjoint_from: | CL:0000764(erythroid lineage cell) |
Children
| is a: | CL:0002027 (CD9-positive, CD41-positive megakaryocyte cell),FF:0101549 (megakaryocytic cell line) |
|---|---|
| derives from: | FF:0011468 (mouse CD41-positive megakaryocyte control sample) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Human (Homo sapiens)
- 10761-110E5
- 11774-124A1 (CD41+ megakaryocyte cancer, donor1)
- 11775-124A2 (CD41+ megakaryocyte control, donor1)
- 11776-124A3 (CD41+ megakaryocyte cancer, donor2)
- 11777-124A4 (CD41+ megakaryocyte control, donor2)
- 11778-124A5 (CD41+ megakaryocyte cancer, donor3)
- 11779-124A6 (CD41+ megakaryocyte control, donor3)
Mouse (Mus musculus)
- 10761-110E5
- 11774-124A1 (CD41+ megakaryocyte cancer, donor1)
- 11775-124A2 (CD41+ megakaryocyte control, donor1)
- 11776-124A3 (CD41+ megakaryocyte cancer, donor2)
- 11777-124A4 (CD41+ megakaryocyte control, donor2)
- 11778-124A5 (CD41+ megakaryocyte cancer, donor3)
- 11779-124A6 (CD41+ megakaryocyte control, donor3)
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000556 (megakaryocyte), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 1.0e-60 | FFCP PHASE2:Mm9::chr3:40893940..40893948,+#_132d24c8283cc5b6b3f35dc48a6ea635 | p@chr3:40893940..40893948, + |
| 1.0e-60 | FFCP PHASE1:Mm9::chr3:40893940..40893948,+#_132d24c8283cc5b6b3f35dc48a6ea635 | p@chr3:40893940..40893948, + |
| 2.34e-60 | FFCP PHASE2:Mm9::chr6:68860437..68860451,-#_4de172110d26fb6f05c5730fb9b36d2b | p@chr6:68860437..68860451, - |
| 2.34e-60 | FFCP PHASE1:Mm9::chr6:68860437..68860451,-#_4de172110d26fb6f05c5730fb9b36d2b | p@chr6:68860437..68860451, - |
| 3.38e-58 | FFCP PHASE2:Mm9::chr3:41343162..41343165,+#_6276cfa83783bf14f4019d8d778be851 | p@chr3:41343162..41343165, + |
| 3.38e-58 | FFCP PHASE1:Mm9::chr3:41343162..41343165,+#_6276cfa83783bf14f4019d8d778be851 | p@chr3:41343162..41343165, + |
| 3.91e-58 | FFCP PHASE1:Mm9::chr9:108276696..108276698,+#_97a28ceb0d01d69a148eebcd1b8335ed | p@chr9:108276696..108276698, + |
| 3.91e-58 | FFCP PHASE2:Mm9::chr9:108276696..108276698,+#_97a28ceb0d01d69a148eebcd1b8335ed | p@chr9:108276696..108276698, + |
| 4.23e-58 | FFCP PHASE2:Mm9::chr2:98503916..98503926,+#_d12a87c03295df4e60e48e15760be08e | p@chr2:98503916..98503926, + |
| 4.23e-58 | FFCP PHASE1:Mm9::chr2:98503916..98503926,+#_d12a87c03295df4e60e48e15760be08e | p@chr2:98503916..98503926, + |
| 1.25e-52 | FFCP PHASE1:Mm9::chr4:105391511..105391533,+#_60133d19d1f9894e3150b53849eb6ac0 | p@chr4:105391511..105391533, + |
| 1.25e-52 | FFCP PHASE2:Mm9::chr4:105391511..105391533,+#_60133d19d1f9894e3150b53849eb6ac0 | p@chr4:105391511..105391533, + |
| 5.18e-52 | FFCP PHASE1:Mm9::chr6:69851116..69851126,-#_5836280e010abe51de02805818ef6143 | p2@ENSMUST00000103370 |
| 5.18e-52 | FFCP PHASE2:Mm9::chr6:69851116..69851126,-#_5836280e010abe51de02805818ef6143 | p2@ENSMUST00000103370 |
| 5.23e-52 | FFCP PHASE1:Mm9::chr10:41613773..41613784,+#_dc4da0847e0d408737c5f01d047476bc | p@chr10:41613773..41613784, + |
| 5.23e-52 | FFCP PHASE1:Mm9::chr17:34376620..34376634,-#_dc4da0847e0d408737c5f01d047476bc | p@chr17:34376620..34376634, - |
| 5.23e-52 | FFCP PHASE2:Mm9::chr17:34376620..34376634,-#_dc4da0847e0d408737c5f01d047476bc | p@chr17:34376620..34376634, - |
| 5.23e-52 | FFCP PHASE2:Mm9::chr10:41613773..41613784,+#_dc4da0847e0d408737c5f01d047476bc | p@chr10:41613773..41613784, + |
| 1.08e-51 | FFCP PHASE1:Mm9::chr9:32425275..32425296,+#_806205f44445fc0772d844b56de433c5 | p@chr9:32425275..32425296, + |
| 1.08e-51 | FFCP PHASE2:Mm9::chr9:32425275..32425296,+#_806205f44445fc0772d844b56de433c5 | p@chr9:32425275..32425296, + |
| 1.74e-51 | FFCP PHASE2:Mm9::chr6:70676952..70676959,-#_da8dbfc8b8d58c86276bcc876a70cce4 | p@chr6:70676952..70676959, - |
| 1.74e-51 | FFCP PHASE1:Mm9::chr6:70676952..70676959,-#_da8dbfc8b8d58c86276bcc876a70cce4 | p@chr6:70676952..70676959, - |
| 6.51e-48 | FFCP PHASE1:Mm9::chr17:88981299..88981314,+#_bb72f369134229df065775c6c748843e | p@chr17:88981299..88981314, + |
| 6.51e-48 | FFCP PHASE2:Mm9::chr17:88981299..88981314,+#_bb72f369134229df065775c6c748843e | p@chr17:88981299..88981314, + |
| 1.98e-47 | FFCP PHASE1:Mm9::chr12:48935035..48935049,+#_e55b0d3d02a3b90232a42454d7b446ef | p@chr12:48935035..48935049, + |
| 1.98e-47 | FFCP PHASE2:Mm9::chr12:48935035..48935049,+#_e55b0d3d02a3b90232a42454d7b446ef | p@chr12:48935035..48935049, + |
| 8.31e-47 | FFCP PHASE2:Mm9::chr11:96193855..96193860,+#_bd99f090b9006b92c58c2837f2556a08 | p@chr11:96193855..96193860, + |
| 8.31e-47 | FFCP PHASE2:Mm9::chr13:30095274..30095283,+#_bd99f090b9006b92c58c2837f2556a08 | p@chr13:30095274..30095283, + |
| 8.31e-47 | FFCP PHASE1:Mm9::chr13:30095274..30095283,+#_bd99f090b9006b92c58c2837f2556a08 | p@chr13:30095274..30095283, + |
| 8.31e-47 | FFCP PHASE1:Mm9::chr11:96193855..96193860,+#_bd99f090b9006b92c58c2837f2556a08 | p@chr11:96193855..96193860, + |
| 1.42e-46 | FFCP PHASE1:Mm9::chr19:11463663..11463671,+#_64b9247ee11c30216ffb56e2863f1452 | p@chr19:11463663..11463671, + |
| 1.42e-46 | FFCP PHASE2:Mm9::chr19:11463663..11463671,+#_64b9247ee11c30216ffb56e2863f1452 | p@chr19:11463663..11463671, + |
| 1.86e-46 | FFCP PHASE2:Mm9::chr3:58321410..58321423,+#_bd5194c89cfc4b2317e68e4edbd98248 | p@chr3:58321410..58321423, + |
| 1.86e-46 | FFCP PHASE1:Mm9::chr17:34400036..34400056,-#_bd5194c89cfc4b2317e68e4edbd98248 | p@chr17:34400036..34400056, - |
| 1.86e-46 | FFCP PHASE2:Mm9::chr17:34400036..34400056,-#_bd5194c89cfc4b2317e68e4edbd98248 | p@chr17:34400036..34400056, - |
| 1.86e-46 | FFCP PHASE2:Mm9::chr13:112658212..112658227,+#_bd5194c89cfc4b2317e68e4edbd98248 | p3@ENSMUST00000128198, p3@uc007rwb.1 |
| 1.86e-46 | FFCP PHASE1:Mm9::chr3:58321410..58321423,+#_bd5194c89cfc4b2317e68e4edbd98248 | p@chr3:58321410..58321423, + |
| 1.86e-46 | FFCP PHASE1:Mm9::chr13:112658212..112658227,+#_bd5194c89cfc4b2317e68e4edbd98248 | p3@ENSMUST00000128198, p3@uc007rwb.1 |
| 9.65e-46 | FFCP PHASE2:Mm9::chr4:135451095..135451110,+#_6b1521ffed2e7a974a5f9bba84a6681c | p4@Cnr2 |
| 9.65e-46 | FFCP PHASE1:Mm9::chr4:135451095..135451110,+#_6b1521ffed2e7a974a5f9bba84a6681c | p4@Cnr2 |
| 9.65e-46 | FFCP PHASE2:Mm9::chr12:114659326..114659343,-#_6b1521ffed2e7a974a5f9bba84a6681c | p5@uc007pgs.1 |
| 9.65e-46 | FFCP PHASE1:Mm9::chr2:99640370..99640374,+#_6b1521ffed2e7a974a5f9bba84a6681c | p@chr2:99640370..99640374, + |
| 9.65e-46 | FFCP PHASE1:Mm9::chr12:114659326..114659343,-#_6b1521ffed2e7a974a5f9bba84a6681c | p5@uc007pgs.1 |
| 9.65e-46 | FFCP PHASE1:Mm9::chr16:19200368..19200390,-#_6b1521ffed2e7a974a5f9bba84a6681c | p2@ENSMUST00000103749 |
| 9.65e-46 | FFCP PHASE2:Mm9::chr16:19200368..19200390,-#_6b1521ffed2e7a974a5f9bba84a6681c | p2@ENSMUST00000103749 |
| 9.65e-46 | FFCP PHASE2:Mm9::chr2:99640370..99640374,+#_6b1521ffed2e7a974a5f9bba84a6681c | p@chr2:99640370..99640374, + |
| 1.19e-45 | FFCP PHASE1:Mm9::chr12:100880892..100880902,-#_f183b4d80fd85f8f29c85f28e8e6d9f2 | p@chr12:100880892..100880902, - |
| 1.19e-45 | FFCP PHASE2:Mm9::chr12:100880892..100880902,-#_f183b4d80fd85f8f29c85f28e8e6d9f2 | p@chr12:100880892..100880902, - |
| 1.82e-45 | FFCP PHASE1:Mm9::chr9:32460050..32460070,+#_ab4936195bea033d3e87a618e969b62d | p@chr9:32460050..32460070, + |
| 1.82e-45 | FFCP PHASE2:Mm9::chr9:32460050..32460070,+#_ab4936195bea033d3e87a618e969b62d | p@chr9:32460050..32460070, + |
| 2.38e-44 | FFCP PHASE1:Mm9::chr9:32487351..32487367,+#_061cc06dc44941a2e4d346d9fffcee00 | p@chr9:32487351..32487367, + |
| 2.38e-44 | FFCP PHASE2:Mm9::chr9:32487351..32487367,+#_061cc06dc44941a2e4d346d9fffcee00 | p@chr9:32487351..32487367, + |
| 2.38e-44 | FFCP PHASE2:Mm9::chr12:114659633..114659652,-#_061cc06dc44941a2e4d346d9fffcee00 | p4@uc007pgs.1 |
| 2.38e-44 | FFCP PHASE1:Mm9::chr12:114659633..114659652,-#_061cc06dc44941a2e4d346d9fffcee00 | p4@uc007pgs.1 |
| 3.35e-44 | FFCP PHASE1:Mm9::chr5:122674421..122674426,+#_70bb9038eea536606c1aebb2a3c70200 | p@chr5:122674421..122674426, + |
| 3.35e-44 | FFCP PHASE2:Mm9::chr5:122674421..122674426,+#_70bb9038eea536606c1aebb2a3c70200 | p@chr5:122674421..122674426, + |
| 5.38e-44 | FFCP PHASE1:Mm9::chr18:35809146..35809153,-#_c5fe6b19031b9d643b5d4d24c6eee4da | p4@2010001M09Rik |
| 5.38e-44 | FFCP PHASE2:Mm9::chr4:44980637..44980644,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p4@ENSMUST00000150111 |
| 5.38e-44 | FFCP PHASE1:Mm9::chr11:102210718..102210728,-#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr11:102210718..102210728, - |
| 5.38e-44 | FFCP PHASE2:Mm9::chr18:55201820..55201826,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr18:55201820..55201826, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr19:43721970..43721975,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr19:43721970..43721975, + |
| 5.38e-44 | FFCP PHASE1:Mm9::chr6:135966781..135966785,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr6:135966781..135966785, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr11:102210718..102210728,-#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr11:102210718..102210728, - |
| 5.38e-44 | FFCP PHASE1:Mm9::chr17:84975629..84975633,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr17:84975629..84975633, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr6:135966781..135966785,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr6:135966781..135966785, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr17:84975629..84975633,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr17:84975629..84975633, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr4:59740918..59740923,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr4:59740918..59740923, + |
| 5.38e-44 | FFCP PHASE1:Mm9::chr19:43721970..43721975,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr19:43721970..43721975, + |
| 5.38e-44 | FFCP PHASE1:Mm9::chr18:55201820..55201826,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr18:55201820..55201826, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr1:156964198..156964201,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr1:156964198..156964201, + |
| 5.38e-44 | FFCP PHASE2:Mm9::chr18:35809146..35809153,-#_c5fe6b19031b9d643b5d4d24c6eee4da | p4@2010001M09Rik |
| 5.38e-44 | FFCP PHASE1:Mm9::chr1:156964198..156964201,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr1:156964198..156964201, + |
| 5.38e-44 | FFCP PHASE1:Mm9::chr4:44980637..44980644,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p4@ENSMUST00000150111 |
| 5.38e-44 | FFCP PHASE1:Mm9::chr4:59740918..59740923,+#_c5fe6b19031b9d643b5d4d24c6eee4da | p@chr4:59740918..59740923, + |
| 6.62e-44 | FFCP PHASE2:Mm9::chr17:34282256..34282276,+#_ed19da4ea9561662f6188c4569255f28 | p4@H2-DMb2 |
| 6.62e-44 | FFCP PHASE1:Mm9::chr17:34282256..34282276,+#_ed19da4ea9561662f6188c4569255f28 | p4@H2-DMb2 |
| 2.83e-41 | FFCP PHASE1:Mm9::chr12:114660740..114660753,+#_8046e7040e1463913d9e7159d1373b19 | p@chr12:114660740..114660753, + |
| 2.83e-41 | FFCP PHASE2:Mm9::chr12:114660740..114660753,+#_8046e7040e1463913d9e7159d1373b19 | p@chr12:114660740..114660753, + |
| 4.64e-41 | FFCP PHASE2:Mm9::chr19:21705252..21705273,-#_f10ea5ba0408681ab8dca166a093cfec | p@chr19:21705252..21705273, - |
| 4.64e-41 | FFCP PHASE1:Mm9::chr19:21705252..21705273,-#_f10ea5ba0408681ab8dca166a093cfec | p@chr19:21705252..21705273, - |
| 7.27e-41 | FFCP PHASE2:Mm9::chr12:114652607..114652619,-#_13ee81766cdefd347a9bc92c6e28564b | p@chr12:114652607..114652619, - |
| 7.27e-41 | FFCP PHASE1:Mm9::chr12:114652607..114652619,-#_13ee81766cdefd347a9bc92c6e28564b | p@chr12:114652607..114652619, - |
| 8.77e-41 | FFCP PHASE1:Mm9::chr13:30095241..30095252,+#_c499b3f9377e6d5a84e26d85a1bf48cb | p@chr13:30095241..30095252, + |
| 8.77e-41 | FFCP PHASE1:Mm9::chr18:36069982..36069991,+#_c499b3f9377e6d5a84e26d85a1bf48cb | p@chr18:36069982..36069991, + |
| 8.77e-41 | FFCP PHASE2:Mm9::chr13:30095241..30095252,+#_c499b3f9377e6d5a84e26d85a1bf48cb | p@chr13:30095241..30095252, + |
| 8.77e-41 | FFCP PHASE2:Mm9::chr18:36069982..36069991,+#_c499b3f9377e6d5a84e26d85a1bf48cb | p@chr18:36069982..36069991, + |
| 1.02e-40 | FFCP PHASE1:Mm9::chr12:53180087..53180104,+#_5f20d10b5ad5102f68b6005d7c83e56c | p@chr12:53180087..53180104, + |
| 1.02e-40 | FFCP PHASE2:Mm9::chr12:114659852..114659872,+#_5f20d10b5ad5102f68b6005d7c83e56c | p@chr12:114659852..114659872, + |
| 1.02e-40 | FFCP PHASE2:Mm9::chr12:53180087..53180104,+#_5f20d10b5ad5102f68b6005d7c83e56c | p@chr12:53180087..53180104, + |
| 1.02e-40 | FFCP PHASE1:Mm9::chr12:114659852..114659872,+#_5f20d10b5ad5102f68b6005d7c83e56c | p@chr12:114659852..114659872, + |
| 1.06e-40 | FFCP PHASE1:Mm9::chr10:50076400..50076404,+#_854668bddbeddff362535dea3fda6c60 | p@chr10:50076400..50076404, + |
| 1.06e-40 | FFCP PHASE2:Mm9::chr10:50076400..50076404,+#_854668bddbeddff362535dea3fda6c60 | p@chr10:50076400..50076404, + |
| 1.91e-40 | FFCP PHASE1:Mm9::chr8:70480444..70480457,+#_1c16f61964ad512940b63478061a8184 | p2@ENSMUST00000127631 |
| 1.91e-40 | FFCP PHASE2:Mm9::chr8:70480444..70480457,+#_1c16f61964ad512940b63478061a8184 | p2@ENSMUST00000127631 |
| 4.18e-40 | FFCP PHASE2:Mm9::chr6:70676615..70676621,+#_b91c8a72a0995fdee99107017da9aefb | p@chr6:70676615..70676621, + |
| 4.18e-40 | FFCP PHASE1:Mm9::chr6:70676615..70676621,+#_b91c8a72a0995fdee99107017da9aefb | p@chr6:70676615..70676621, + |
| 2.4e-39 | FFCP PHASE1:Mm9::chr1:134238914..134238921,+#_7b507ef6159f077b542d577826c06d87 | p@chr1:134238914..134238921, + |
| 2.4e-39 | FFCP PHASE1:Mm9::chr12:100880924..100880933,-#_7b507ef6159f077b542d577826c06d87 | p@chr12:100880924..100880933, - |
| 2.4e-39 | FFCP PHASE2:Mm9::chr1:134238914..134238921,+#_7b507ef6159f077b542d577826c06d87 | p@chr1:134238914..134238921, + |
| 2.4e-39 | FFCP PHASE2:Mm9::chr12:100880924..100880933,-#_7b507ef6159f077b542d577826c06d87 | p@chr12:100880924..100880933, - |
