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CL:0000556

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Name:megakaryocyte
Namespace:FANTOM
Definition:"A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm." [ISBN:0721601464, MESH:D008533]
Xrefs:
links:

BTO:0000843

FMA:83555
Synonyms: "megacaryocyte" EXACT []
"megalocaryocyte" EXACT []
"megalokaryocyte" EXACT []
Comments:Megakaryocytes are reportedly CD181-positive and CD182-positive.


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0000763(myeloid cell),CL:1001610(bone marrow hematopoietic cell)
disjoint_from:CL:0000764(erythroid lineage cell)
develops_from:CL:0000553(megakaryocyte progenitor cell)
part_of:UBERON:0002371(bone marrow)



Children


is a:CL:0002027 (CD9-positive, CD41-positive megakaryocyte cell),FF:0101549 (megakaryocytic cell line)
derives from:FF:0011468 (mouse CD41-positive megakaryocyte control sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000556 (megakaryocyte), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
1.0e-60FFCP PHASE2:Mm9::chr3:40893940..40893948,+#_132d24c8283cc5b6b3f35dc48a6ea635p@chr3:40893940..40893948, +
1.0e-60FFCP PHASE1:Mm9::chr3:40893940..40893948,+#_132d24c8283cc5b6b3f35dc48a6ea635p@chr3:40893940..40893948, +
2.34e-60FFCP PHASE1:Mm9::chr6:68860437..68860451,-#_4de172110d26fb6f05c5730fb9b36d2bp@chr6:68860437..68860451, -
2.34e-60FFCP PHASE2:Mm9::chr6:68860437..68860451,-#_4de172110d26fb6f05c5730fb9b36d2bp@chr6:68860437..68860451, -
3.38e-58FFCP PHASE2:Mm9::chr3:41343162..41343165,+#_6276cfa83783bf14f4019d8d778be851p@chr3:41343162..41343165, +
3.38e-58FFCP PHASE1:Mm9::chr3:41343162..41343165,+#_6276cfa83783bf14f4019d8d778be851p@chr3:41343162..41343165, +
3.91e-58FFCP PHASE2:Mm9::chr9:108276696..108276698,+#_97a28ceb0d01d69a148eebcd1b8335edp@chr9:108276696..108276698, +
3.91e-58FFCP PHASE1:Mm9::chr9:108276696..108276698,+#_97a28ceb0d01d69a148eebcd1b8335edp@chr9:108276696..108276698, +
4.23e-58FFCP PHASE2:Mm9::chr2:98503916..98503926,+#_d12a87c03295df4e60e48e15760be08ep@chr2:98503916..98503926, +
4.23e-58FFCP PHASE1:Mm9::chr2:98503916..98503926,+#_d12a87c03295df4e60e48e15760be08ep@chr2:98503916..98503926, +
1.25e-52FFCP PHASE1:Mm9::chr4:105391511..105391533,+#_60133d19d1f9894e3150b53849eb6ac0p@chr4:105391511..105391533, +
1.25e-52FFCP PHASE2:Mm9::chr4:105391511..105391533,+#_60133d19d1f9894e3150b53849eb6ac0p@chr4:105391511..105391533, +
5.18e-52FFCP PHASE1:Mm9::chr6:69851116..69851126,-#_5836280e010abe51de02805818ef6143p2@ENSMUST00000103370
5.18e-52FFCP PHASE2:Mm9::chr6:69851116..69851126,-#_5836280e010abe51de02805818ef6143p2@ENSMUST00000103370
5.23e-52FFCP PHASE1:Mm9::chr10:41613773..41613784,+#_dc4da0847e0d408737c5f01d047476bcp@chr10:41613773..41613784, +
5.23e-52FFCP PHASE2:Mm9::chr10:41613773..41613784,+#_dc4da0847e0d408737c5f01d047476bcp@chr10:41613773..41613784, +
5.23e-52FFCP PHASE1:Mm9::chr17:34376620..34376634,-#_dc4da0847e0d408737c5f01d047476bcp@chr17:34376620..34376634, -
5.23e-52FFCP PHASE2:Mm9::chr17:34376620..34376634,-#_dc4da0847e0d408737c5f01d047476bcp@chr17:34376620..34376634, -
1.08e-51FFCP PHASE2:Mm9::chr9:32425275..32425296,+#_806205f44445fc0772d844b56de433c5p@chr9:32425275..32425296, +
1.08e-51FFCP PHASE1:Mm9::chr9:32425275..32425296,+#_806205f44445fc0772d844b56de433c5p@chr9:32425275..32425296, +
1.74e-51FFCP PHASE1:Mm9::chr6:70676952..70676959,-#_da8dbfc8b8d58c86276bcc876a70cce4p@chr6:70676952..70676959, -
1.74e-51FFCP PHASE2:Mm9::chr6:70676952..70676959,-#_da8dbfc8b8d58c86276bcc876a70cce4p@chr6:70676952..70676959, -
6.51e-48FFCP PHASE2:Mm9::chr17:88981299..88981314,+#_bb72f369134229df065775c6c748843ep@chr17:88981299..88981314, +
6.51e-48FFCP PHASE1:Mm9::chr17:88981299..88981314,+#_bb72f369134229df065775c6c748843ep@chr17:88981299..88981314, +
1.98e-47FFCP PHASE2:Mm9::chr12:48935035..48935049,+#_e55b0d3d02a3b90232a42454d7b446efp@chr12:48935035..48935049, +
1.98e-47FFCP PHASE1:Mm9::chr12:48935035..48935049,+#_e55b0d3d02a3b90232a42454d7b446efp@chr12:48935035..48935049, +
8.31e-47FFCP PHASE1:Mm9::chr11:96193855..96193860,+#_bd99f090b9006b92c58c2837f2556a08p@chr11:96193855..96193860, +
8.31e-47FFCP PHASE1:Mm9::chr13:30095274..30095283,+#_bd99f090b9006b92c58c2837f2556a08p@chr13:30095274..30095283, +
8.31e-47FFCP PHASE2:Mm9::chr13:30095274..30095283,+#_bd99f090b9006b92c58c2837f2556a08p@chr13:30095274..30095283, +
8.31e-47FFCP PHASE2:Mm9::chr11:96193855..96193860,+#_bd99f090b9006b92c58c2837f2556a08p@chr11:96193855..96193860, +
1.42e-46FFCP PHASE2:Mm9::chr19:11463663..11463671,+#_64b9247ee11c30216ffb56e2863f1452p@chr19:11463663..11463671, +
1.42e-46FFCP PHASE1:Mm9::chr19:11463663..11463671,+#_64b9247ee11c30216ffb56e2863f1452p@chr19:11463663..11463671, +
1.86e-46FFCP PHASE2:Mm9::chr3:58321410..58321423,+#_bd5194c89cfc4b2317e68e4edbd98248p@chr3:58321410..58321423, +
1.86e-46FFCP PHASE2:Mm9::chr13:112658212..112658227,+#_bd5194c89cfc4b2317e68e4edbd98248p3@ENSMUST00000128198, p3@uc007rwb.1
1.86e-46FFCP PHASE1:Mm9::chr3:58321410..58321423,+#_bd5194c89cfc4b2317e68e4edbd98248p@chr3:58321410..58321423, +
1.86e-46FFCP PHASE2:Mm9::chr17:34400036..34400056,-#_bd5194c89cfc4b2317e68e4edbd98248p@chr17:34400036..34400056, -
1.86e-46FFCP PHASE1:Mm9::chr13:112658212..112658227,+#_bd5194c89cfc4b2317e68e4edbd98248p3@ENSMUST00000128198, p3@uc007rwb.1
1.86e-46FFCP PHASE1:Mm9::chr17:34400036..34400056,-#_bd5194c89cfc4b2317e68e4edbd98248p@chr17:34400036..34400056, -
9.65e-46FFCP PHASE2:Mm9::chr16:19200368..19200390,-#_6b1521ffed2e7a974a5f9bba84a6681cp2@ENSMUST00000103749
9.65e-46FFCP PHASE1:Mm9::chr4:135451095..135451110,+#_6b1521ffed2e7a974a5f9bba84a6681cp4@Cnr2
9.65e-46FFCP PHASE1:Mm9::chr16:19200368..19200390,-#_6b1521ffed2e7a974a5f9bba84a6681cp2@ENSMUST00000103749
9.65e-46FFCP PHASE1:Mm9::chr2:99640370..99640374,+#_6b1521ffed2e7a974a5f9bba84a6681cp@chr2:99640370..99640374, +
9.65e-46FFCP PHASE2:Mm9::chr4:135451095..135451110,+#_6b1521ffed2e7a974a5f9bba84a6681cp4@Cnr2
9.65e-46FFCP PHASE2:Mm9::chr2:99640370..99640374,+#_6b1521ffed2e7a974a5f9bba84a6681cp@chr2:99640370..99640374, +
9.65e-46FFCP PHASE2:Mm9::chr12:114659326..114659343,-#_6b1521ffed2e7a974a5f9bba84a6681cp5@uc007pgs.1
9.65e-46FFCP PHASE1:Mm9::chr12:114659326..114659343,-#_6b1521ffed2e7a974a5f9bba84a6681cp5@uc007pgs.1
1.19e-45FFCP PHASE1:Mm9::chr12:100880892..100880902,-#_f183b4d80fd85f8f29c85f28e8e6d9f2p@chr12:100880892..100880902, -
1.19e-45FFCP PHASE2:Mm9::chr12:100880892..100880902,-#_f183b4d80fd85f8f29c85f28e8e6d9f2p@chr12:100880892..100880902, -
1.82e-45FFCP PHASE2:Mm9::chr9:32460050..32460070,+#_ab4936195bea033d3e87a618e969b62dp@chr9:32460050..32460070, +
1.82e-45FFCP PHASE1:Mm9::chr9:32460050..32460070,+#_ab4936195bea033d3e87a618e969b62dp@chr9:32460050..32460070, +
2.38e-44FFCP PHASE2:Mm9::chr9:32487351..32487367,+#_061cc06dc44941a2e4d346d9fffcee00p@chr9:32487351..32487367, +
2.38e-44FFCP PHASE2:Mm9::chr12:114659633..114659652,-#_061cc06dc44941a2e4d346d9fffcee00p4@uc007pgs.1
2.38e-44FFCP PHASE1:Mm9::chr12:114659633..114659652,-#_061cc06dc44941a2e4d346d9fffcee00p4@uc007pgs.1
2.38e-44FFCP PHASE1:Mm9::chr9:32487351..32487367,+#_061cc06dc44941a2e4d346d9fffcee00p@chr9:32487351..32487367, +
3.35e-44FFCP PHASE2:Mm9::chr5:122674421..122674426,+#_70bb9038eea536606c1aebb2a3c70200p@chr5:122674421..122674426, +
3.35e-44FFCP PHASE1:Mm9::chr5:122674421..122674426,+#_70bb9038eea536606c1aebb2a3c70200p@chr5:122674421..122674426, +
5.38e-44FFCP PHASE2:Mm9::chr4:44980637..44980644,+#_c5fe6b19031b9d643b5d4d24c6eee4dap4@ENSMUST00000150111
5.38e-44FFCP PHASE2:Mm9::chr19:43721970..43721975,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr19:43721970..43721975, +
5.38e-44FFCP PHASE2:Mm9::chr4:59740918..59740923,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr4:59740918..59740923, +
5.38e-44FFCP PHASE2:Mm9::chr18:35809146..35809153,-#_c5fe6b19031b9d643b5d4d24c6eee4dap4@2010001M09Rik
5.38e-44FFCP PHASE1:Mm9::chr11:102210718..102210728,-#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr11:102210718..102210728, -
5.38e-44FFCP PHASE1:Mm9::chr18:35809146..35809153,-#_c5fe6b19031b9d643b5d4d24c6eee4dap4@2010001M09Rik
5.38e-44FFCP PHASE2:Mm9::chr6:135966781..135966785,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr6:135966781..135966785, +
5.38e-44FFCP PHASE2:Mm9::chr17:84975629..84975633,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr17:84975629..84975633, +
5.38e-44FFCP PHASE1:Mm9::chr4:44980637..44980644,+#_c5fe6b19031b9d643b5d4d24c6eee4dap4@ENSMUST00000150111
5.38e-44FFCP PHASE1:Mm9::chr4:59740918..59740923,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr4:59740918..59740923, +
5.38e-44FFCP PHASE2:Mm9::chr11:102210718..102210728,-#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr11:102210718..102210728, -
5.38e-44FFCP PHASE2:Mm9::chr18:55201820..55201826,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr18:55201820..55201826, +
5.38e-44FFCP PHASE1:Mm9::chr19:43721970..43721975,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr19:43721970..43721975, +
5.38e-44FFCP PHASE2:Mm9::chr1:156964198..156964201,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr1:156964198..156964201, +
5.38e-44FFCP PHASE1:Mm9::chr18:55201820..55201826,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr18:55201820..55201826, +
5.38e-44FFCP PHASE1:Mm9::chr6:135966781..135966785,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr6:135966781..135966785, +
5.38e-44FFCP PHASE1:Mm9::chr17:84975629..84975633,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr17:84975629..84975633, +
5.38e-44FFCP PHASE1:Mm9::chr1:156964198..156964201,+#_c5fe6b19031b9d643b5d4d24c6eee4dap@chr1:156964198..156964201, +
6.62e-44FFCP PHASE1:Mm9::chr17:34282256..34282276,+#_ed19da4ea9561662f6188c4569255f28p4@H2-DMb2
6.62e-44FFCP PHASE2:Mm9::chr17:34282256..34282276,+#_ed19da4ea9561662f6188c4569255f28p4@H2-DMb2
2.83e-41FFCP PHASE2:Mm9::chr12:114660740..114660753,+#_8046e7040e1463913d9e7159d1373b19p@chr12:114660740..114660753, +
2.83e-41FFCP PHASE1:Mm9::chr12:114660740..114660753,+#_8046e7040e1463913d9e7159d1373b19p@chr12:114660740..114660753, +
4.64e-41FFCP PHASE2:Mm9::chr19:21705252..21705273,-#_f10ea5ba0408681ab8dca166a093cfecp@chr19:21705252..21705273, -
4.64e-41FFCP PHASE1:Mm9::chr19:21705252..21705273,-#_f10ea5ba0408681ab8dca166a093cfecp@chr19:21705252..21705273, -
7.27e-41FFCP PHASE2:Mm9::chr12:114652607..114652619,-#_13ee81766cdefd347a9bc92c6e28564bp@chr12:114652607..114652619, -
7.27e-41FFCP PHASE1:Mm9::chr12:114652607..114652619,-#_13ee81766cdefd347a9bc92c6e28564bp@chr12:114652607..114652619, -
8.77e-41FFCP PHASE1:Mm9::chr13:30095241..30095252,+#_c499b3f9377e6d5a84e26d85a1bf48cbp@chr13:30095241..30095252, +
8.77e-41FFCP PHASE2:Mm9::chr13:30095241..30095252,+#_c499b3f9377e6d5a84e26d85a1bf48cbp@chr13:30095241..30095252, +
8.77e-41FFCP PHASE2:Mm9::chr18:36069982..36069991,+#_c499b3f9377e6d5a84e26d85a1bf48cbp@chr18:36069982..36069991, +
8.77e-41FFCP PHASE1:Mm9::chr18:36069982..36069991,+#_c499b3f9377e6d5a84e26d85a1bf48cbp@chr18:36069982..36069991, +
1.02e-40FFCP PHASE1:Mm9::chr12:114659852..114659872,+#_5f20d10b5ad5102f68b6005d7c83e56cp@chr12:114659852..114659872, +
1.02e-40FFCP PHASE1:Mm9::chr12:53180087..53180104,+#_5f20d10b5ad5102f68b6005d7c83e56cp@chr12:53180087..53180104, +
1.02e-40FFCP PHASE2:Mm9::chr12:53180087..53180104,+#_5f20d10b5ad5102f68b6005d7c83e56cp@chr12:53180087..53180104, +
1.02e-40FFCP PHASE2:Mm9::chr12:114659852..114659872,+#_5f20d10b5ad5102f68b6005d7c83e56cp@chr12:114659852..114659872, +
1.06e-40FFCP PHASE1:Mm9::chr10:50076400..50076404,+#_854668bddbeddff362535dea3fda6c60p@chr10:50076400..50076404, +
1.06e-40FFCP PHASE2:Mm9::chr10:50076400..50076404,+#_854668bddbeddff362535dea3fda6c60p@chr10:50076400..50076404, +
1.91e-40FFCP PHASE1:Mm9::chr8:70480444..70480457,+#_1c16f61964ad512940b63478061a8184p2@ENSMUST00000127631
1.91e-40FFCP PHASE2:Mm9::chr8:70480444..70480457,+#_1c16f61964ad512940b63478061a8184p2@ENSMUST00000127631
4.18e-40FFCP PHASE1:Mm9::chr6:70676615..70676621,+#_b91c8a72a0995fdee99107017da9aefbp@chr6:70676615..70676621, +
4.18e-40FFCP PHASE2:Mm9::chr6:70676615..70676621,+#_b91c8a72a0995fdee99107017da9aefbp@chr6:70676615..70676621, +
2.4e-39FFCP PHASE2:Mm9::chr12:100880924..100880933,-#_7b507ef6159f077b542d577826c06d87p@chr12:100880924..100880933, -
2.4e-39FFCP PHASE1:Mm9::chr12:100880924..100880933,-#_7b507ef6159f077b542d577826c06d87p@chr12:100880924..100880933, -
2.4e-39FFCP PHASE1:Mm9::chr1:134238914..134238921,+#_7b507ef6159f077b542d577826c06d87p@chr1:134238914..134238921, +
2.4e-39FFCP PHASE2:Mm9::chr1:134238914..134238921,+#_7b507ef6159f077b542d577826c06d87p@chr1:134238914..134238921, +