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MCL coexpression mm9:1175: Difference between revisions

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|gostat_on_MCL_coexpression=GO:0030027;lamellipodium;0.00946547036280019;74117,11308!GO:0031252;leading edge;0.0114244153791895;74117,11308!GO:0030296;protein tyrosine kinase activator activity;0.0197200838402074;11308!GO:0015629;actin cytoskeleton;0.0295639229480919;22388,74117!GO:0005856;cytoskeleton;0.0295639229480919;22388,74117,11308!GO:0005545;phosphatidylinositol binding;0.0295639229480919;83436!GO:0003779;actin binding;0.0325950479901803;22388,74117!GO:0030295;protein kinase activator activity;0.0332457491844284;11308!GO:0019209;kinase activator activity;0.039386181975423;11308!GO:0008092;cytoskeletal protein binding;0.0429271196841837;22388,74117!GO:0042995;cell projection;0.0461570015377674;74117,11308!
|gostat_on_MCL_coexpression=GO:0030027;lamellipodium;0.00946547036280019;74117,11308!GO:0031252;leading edge;0.0114244153791895;74117,11308!GO:0030296;protein tyrosine kinase activator activity;0.0197200838402074;11308!GO:0015629;actin cytoskeleton;0.0295639229480919;22388,74117!GO:0005856;cytoskeleton;0.0295639229480919;22388,74117,11308!GO:0005545;phosphatidylinositol binding;0.0295639229480919;83436!GO:0003779;actin binding;0.0325950479901803;22388,74117!GO:0030295;protein kinase activator activity;0.0332457491844284;11308!GO:0019209;kinase activator activity;0.039386181975423;11308!GO:0008092;cytoskeletal protein binding;0.0429271196841837;22388,74117!GO:0042995;cell projection;0.0461570015377674;74117,11308!
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0005409!3.09e-13!47;UBERON:0000160!4.96e-11!31;UBERON:0004923!4.51e-10!24;UBERON:0004119!2.61e-09!118;UBERON:0000925!2.61e-09!118;UBERON:0006595!2.61e-09!118;UBERON:0001007!1.35e-08!116;UBERON:0001555!1.35e-08!116;UBERON:0007026!1.35e-08!116;UBERON:0000344!2.75e-08!15;UBERON:0004921!8.50e-08!114;UBERON:0001242!4.47e-07!13;UBERON:0000060!4.47e-07!13;UBERON:0001262!4.47e-07!13;UBERON:0004786!4.47e-07!13
}}
}}

Revision as of 16:27, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr1:127332009..127332021,-p4@Actr3
Mm9::chr2:22895697..22895721,-p1@Abi1
Mm9::chr2:93302614..93302651,-p2@Cd82
Mm9::chr5:38952793..38952861,-p1@Wdr1
Mm9::chr7:13620071..13620131,-p1@Chmp2a
Mm9::chr8:26212206..26212264,-p1@Plekha2
Mm9::chr9:122203479..122203525,-p1@Ano10


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0030027lamellipodium0.00946547036280019
GO:0031252leading edge0.0114244153791895
GO:0030296protein tyrosine kinase activator activity0.0197200838402074
GO:0015629actin cytoskeleton0.0295639229480919
GO:0005856cytoskeleton0.0295639229480919
GO:0005545phosphatidylinositol binding0.0295639229480919
GO:0003779actin binding0.0325950479901803
GO:0030295protein kinase activator activity0.0332457491844284
GO:0019209kinase activator activity0.039386181975423
GO:0008092cytoskeletal protein binding0.0429271196841837
GO:0042995cell projection0.0461570015377674



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
gastrointestinal system3.09e-1347
intestine4.96e-1131
organ component layer4.51e-1024
endoderm-derived structure2.61e-09118
endoderm2.61e-09118
presumptive endoderm2.61e-09118
digestive system1.35e-08116
digestive tract1.35e-08116
primitive gut1.35e-08116
mucosa2.75e-0815
subdivision of digestive tract8.50e-08114
intestinal mucosa4.47e-0713
anatomical wall4.47e-0713
wall of intestine4.47e-0713
gastrointestinal system mucosa4.47e-0713


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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