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{{Coexpression_clusters
{
|coexpression_dpi_cluster_scores_median=0,0,0,

Latest revision as of 10:29, 17 September 2013


Full id: C94_smallcell_adrenal_lung_nonsmall_small_somatostatinoma_teratocarcinoma



Phase1 CAGE Peaks

Hg19::chr10:126027036..126027041,-p@chr10:126027036..126027041
-
Hg19::chr10:5407022..5407032,+p4@UCN3
Hg19::chr10:77056134..77056153,+p1@ZNF503-AS1
Hg19::chr10:77056181..77056190,+p2@ZNF503-AS1
Hg19::chr11:115158193..115158232,-p15@CADM1
Hg19::chr11:14992712..14992724,-p2@CALCA
Hg19::chr11:1643592..1643602,+p@chr11:1643592..1643602
+
Hg19::chr11:4718911..4718938,-p2@OR51E2
Hg19::chr11:4718944..4718953,-p4@OR51E2
Hg19::chr11:4719014..4719028,-p3@OR51E2
Hg19::chr11:4719072..4719089,-p1@OR51E2
Hg19::chr11:60467048..60467063,+p4@MS4A8B
Hg19::chr12:103353319..103353328,+p@chr12:103353319..103353328
+
Hg19::chr12:127992016..127992052,+p@chr12:127992016..127992052
+
Hg19::chr12:128077388..128077416,+p@chr12:128077388..128077416
+
Hg19::chr12:15784419..15784458,-p18@EPS8
Hg19::chr12:22852866..22852887,+p1@ENST00000536744
Hg19::chr12:23791058..23791099,+p@chr12:23791058..23791099
+
Hg19::chr12:50284871..50284904,-p@chr12:50284871..50284904
-
Hg19::chr12:86268065..86268080,+p1@NTS
Hg19::chr12:86272210..86272219,+p@chr12:86272210..86272219
+
Hg19::chr12:86272273..86272280,+p@chr12:86272273..86272280
+
Hg19::chr12:92401823..92401837,+p@chr12:92401823..92401837
+
Hg19::chr12:92401866..92401875,+p@chr12:92401866..92401875
+
Hg19::chr13:26619917..26619921,-p@chr13:26619917..26619921
-
Hg19::chr13:26626147..26626161,-p@chr13:26626147..26626161
-
Hg19::chr13:33498605..33498607,-p@chr13:33498605..33498607
-
Hg19::chr13:38508582..38508616,+p2@CR627261
Hg19::chr13:93329950..93329974,-p@chr13:93329950..93329974
-
Hg19::chr13:93372213..93372253,-p1@GPC5-AS1
Hg19::chr13:93372254..93372268,-p2@GPC5-AS1
Hg19::chr13:93372269..93372274,-p3@GPC5-AS1
Hg19::chr13:93372283..93372290,-p4@GPC5-AS1
Hg19::chr13:93439916..93439921,-p@chr13:93439916..93439921
-
Hg19::chr13:93508642..93508652,-p@chr13:93508642..93508652
-
Hg19::chr14:105637918..105637925,-p@chr14:105637918..105637925
-
Hg19::chr14:105643341..105643359,-p@chr14:105643341..105643359
-
Hg19::chr14:76278486..76278493,+p@chr14:76278486..76278493
+
Hg19::chr14:76447825..76447863,-p5@TGFB3
Hg19::chr15:51981498..51981513,+p@chr15:51981498..51981513
+
Hg19::chr15:51984388..51984400,+p6@SCG3
Hg19::chr15:59908653..59908680,+p4@GCNT3
Hg19::chr15:74528745..74528750,+p8@CCDC33
Hg19::chr15:74612015..74612053,-p@chr15:74612015..74612053
-
Hg19::chr16:1132642..1132649,-p@chr16:1132642..1132649
-
Hg19::chr16:1205163..1205193,+p@chr16:1205163..1205193
+
Hg19::chr16:12121188..12121212,+p@chr16:12121188..12121212
+
Hg19::chr16:15670786..15670791,-p@chr16:15670786..15670791
-
Hg19::chr16:15672837..15672851,+p@chr16:15672837..15672851
+
Hg19::chr16:15699973..15700008,-p10@KIAA0430
Hg19::chr16:1631093..1631103,-p@chr16:1631093..1631103
-
Hg19::chr16:1968408..1968425,-p1@HS3ST6
Hg19::chr16:23313614..23313629,+p2@SCNN1B
Hg19::chr16:23313645..23313671,+p1@SCNN1B
Hg19::chr16:71378536..71378548,-p@chr16:71378536..71378548
-
Hg19::chr16:735116..735143,-p@chr16:735116..735143
-
Hg19::chr17:1666131..1666142,+p@chr17:1666131..1666142
+
Hg19::chr18:56815532..56815544,+p@chr18:56815532..56815544
+
Hg19::chr18:56816249..56816258,+p@chr18:56816249..56816258
+
Hg19::chr18:56816267..56816276,+p@chr18:56816267..56816276
+
Hg19::chr18:56816796..56816816,+p@chr18:56816796..56816816
+
Hg19::chr18:56819783..56819803,+p@chr18:56819783..56819803
+
Hg19::chr18:56822974..56823004,-p@chr18:56822974..56823004
-
Hg19::chr18:71843121..71843138,+p@chr18:71843121..71843138
+
Hg19::chr18:71843159..71843180,+p@chr18:71843159..71843180
+
Hg19::chr18:904938..904986,+p2@ADCYAP1
Hg19::chr18:904994..905011,+p5@ADCYAP1
Hg19::chr18:905092..905103,+p12@ADCYAP1
Hg19::chr18:905104..905118,+p10@ADCYAP1
Hg19::chr19:10823418..10823430,+p15@DNM2
Hg19::chr19:10823451..10823463,+p10@DNM2
Hg19::chr19:10823464..10823473,+p16@DNM2
Hg19::chr19:3068219..3068225,-p@chr19:3068219..3068225
-
Hg19::chr19:42638173..42638181,+p1@ENST00000531517
Hg19::chr19:51537964..51537973,-p6@KLK12
Hg19::chr19:51537982..51537991,-p8@KLK12
Hg19::chr19:51538017..51538048,-p3@KLK12
Hg19::chr19:51538096..51538109,-p5@KLK12
Hg19::chr19:51538121..51538134,-p4@KLK12
Hg19::chr1:147084502..147084507,+p@chr1:147084502..147084507
+
Hg19::chr1:15416193..15416195,-p@chr1:15416193..15416195
-
Hg19::chr1:165198157..165198181,-p@chr1:165198157..165198181
-
Hg19::chr1:17906670..17906682,+p17@ARHGEF10L
Hg19::chr1:18807428..18807451,+p2@KLHDC7A
Hg19::chr1:188791401..188791408,-p@chr1:188791401..188791408
-
Hg19::chr1:209237425..209237437,-p@chr1:209237425..209237437
-
Hg19::chr1:222763113..222763144,-p3@TAF1A
Hg19::chr1:222763161..222763178,-p4@TAF1A
Hg19::chr1:223853355..223853378,-p2@CAPN8
Hg19::chr1:223853388..223853408,-p1@CAPN8
Hg19::chr1:223853431..223853436,-p4@CAPN8
Hg19::chr1:226067570..226067582,-p@chr1:226067570..226067582
-
Hg19::chr1:27240361..27240377,-p2@NR0B2
Hg19::chr1:39749767..39749791,+p17@MACF1
Hg19::chr1:52442908..52442917,-p9@RAB3B
Hg19::chr1:55446384..55446413,+p3@TMEM61
Hg19::chr20:10996541..10996543,+p@chr20:10996541..10996543
+
Hg19::chr20:17207711..17207722,+p3@PCSK2
Hg19::chr20:2310990..2310996,+p@chr20:2310990..2310996
+
Hg19::chr20:2311002..2311015,+p@chr20:2311002..2311015
+
Hg19::chr20:3184528..3184549,-p@chr20:3184528..3184549
-
Hg19::chr20:3184707..3184740,+p@chr20:3184707..3184740
+
Hg19::chr20:31958369..31958376,-p@chr20:31958369..31958376
-
Hg19::chr20:31958409..31958418,-p@chr20:31958409..31958418
-
Hg19::chr20:33114038..33114096,+p2@DYNLRB1
Hg19::chr20:3780693..3780714,+p17@CDC25B
Hg19::chr20:49241036..49241049,-p@chr20:49241036..49241049
-
Hg19::chr20:5896962..5896986,+p@chr20:5896962..5896986
+
Hg19::chr22:24251729..24251732,-p@chr22:24251729..24251732
-
Hg19::chr22:25297679..25297722,+p@chr22:25297679..25297722
+
Hg19::chr2:135011636..135011649,+p8@MGAT5
Hg19::chr2:163942394..163942398,+p@chr2:163942394..163942398
+
Hg19::chr2:170367210..170367234,+p6@KBTBD10
Hg19::chr2:191221240..191221253,+p17@INPP1
Hg19::chr2:214788522..214788538,+p2@SPAG16
Hg19::chr2:236414196..236414199,+p1@AGAP1-IT1
Hg19::chr2:2617159..2617172,-p@chr2:2617159..2617172
-
Hg19::chr2:99758223..99758246,+p3@C2orf15
p6@MRPL30
Hg19::chr3:129813701..129813712,+p@chr3:129813701..129813712
+
Hg19::chr3:13369325..13369334,-p6@NUP210
Hg19::chr3:148994474..148994479,-p1@CPHL1P
Hg19::chr3:176474114..176474132,-p@chr3:176474114..176474132
-
Hg19::chr3:186713943..186713982,+p35@ST6GAL1
Hg19::chr3:20038294..20038297,+p1@ENST00000364675
Hg19::chr3:55328211..55328214,+p@chr3:55328211..55328214
+
Hg19::chr3:55361260..55361286,-p@chr3:55361260..55361286
-
Hg19::chr4:10736435..10736454,-p@chr4:10736435..10736454
-
Hg19::chr4:10736455..10736475,-p@chr4:10736455..10736475
-
Hg19::chr4:10736487..10736498,-p@chr4:10736487..10736498
-
Hg19::chr4:114880636..114880650,+p@chr4:114880636..114880650
+
Hg19::chr4:116034768..116034781,-p2@NDST4
Hg19::chr4:144354723..144354734,+p@chr4:144354723..144354734
+
Hg19::chr4:156364770..156364801,+p@chr4:156364770..156364801
+
Hg19::chr5:102143765..102143784,+p22@PAM
Hg19::chr5:102143805..102143822,+p13@PAM
Hg19::chr5:102143830..102143844,+p18@PAM
Hg19::chr5:102143863..102143874,+p23@PAM
Hg19::chr5:125800836..125800850,+p21@GRAMD3
Hg19::chr5:138429594..138429616,-p7@SIL1
Hg19::chr5:15902227..15902252,-p@chr5:15902227..15902252
-
Hg19::chr5:40415240..40415245,+p@chr5:40415240..40415245
+
Hg19::chr5:54157..54174,+p@chr5:54157..54174
+
Hg19::chr6:132980317..132980326,-p@chr6:132980317..132980326
-
Hg19::chr6:132980338..132980346,-p@chr6:132980338..132980346
-
Hg19::chr6:24980950..24980956,+p@chr6:24980950..24980956
+
Hg19::chr6:32134832..32134862,+p11@EGFL8
Hg19::chr6:41168871..41168911,-p1@TREML2
Hg19::chr6:41168920..41168927,-p4@TREML2
Hg19::chr6:48219854..48219891,-p@chr6:48219854..48219891
-
Hg19::chr6:49695621..49695625,-p@chr6:49695621..49695625
-
Hg19::chr6:49696401..49696408,-p@chr6:49696401..49696408
-
Hg19::chr6:49701451..49701462,-p@chr6:49701451..49701462
-
Hg19::chr6:49712072..49712087,-p2@CRISP3
Hg19::chr7:100816687..100816697,-p4@NAT16
Hg19::chr7:130600779..130600797,+p@chr7:130600779..130600797
+
Hg19::chr7:130600802..130600814,+p@chr7:130600802..130600814
+
Hg19::chr7:150499243..150499249,-p@chr7:150499243..150499249
-
Hg19::chr7:150499392..150499424,-p@chr7:150499392..150499424
-
Hg19::chr7:150499428..150499436,-p@chr7:150499428..150499436
-
Hg19::chr7:150499437..150499449,-p@chr7:150499437..150499449
-
Hg19::chr7:150500070..150500081,+p27@TMEM176A
Hg19::chr7:150500286..150500288,-p@chr7:150500286..150500288
-
Hg19::chr7:150500382..150500396,+p9@TMEM176A
Hg19::chr7:150500441..150500448,+p34@TMEM176A
Hg19::chr7:150675342..150675363,-p4@KCNH2
Hg19::chr7:150675372..150675417,-p1@KCNH2
Hg19::chr7:21985656..21985667,-p3@CDCA7L
Hg19::chr7:26415673..26415697,-p@chr7:26415673..26415697
-
Hg19::chr7:26578438..26578451,-p2@KIAA0087
Hg19::chr7:26578466..26578485,-p1@KIAA0087
Hg19::chr7:27191798..27191816,-p@chr7:27191798..27191816
-
Hg19::chr7:29971838..29971870,-p@chr7:29971838..29971870
-
Hg19::chr7:36327304..36327316,+p11@EEPD1
Hg19::chr7:36327318..36327333,+p14@EEPD1
Hg19::chr7:872107..872145,+p2@SUN1
Hg19::chr7:92300854..92300857,-p@chr7:92300854..92300857
-
Hg19::chr7:92300908..92300913,-p@chr7:92300908..92300913
-
Hg19::chr7:99541928..99541935,-p@chr7:99541928..99541935
-
Hg19::chr8:10122760..10122784,+p@chr8:10122760..10122784
+
Hg19::chr8:104148509..104148517,+p@chr8:104148509..104148517
+
Hg19::chr8:125183765..125183776,-p1@ENST00000520031
p1@uc003yqy.1
Hg19::chr8:139856402..139856426,-p@chr8:139856402..139856426
-
Hg19::chr8:141018634..141018657,-p6@TRAPPC9
Hg19::chr8:141018664..141018674,-p15@TRAPPC9
Hg19::chr8:2104622..2104638,+p2@ENST00000518316
Hg19::chr8:29592736..29592744,-p3@C8orf75
Hg19::chr9:130738884..130738902,-p@chr9:130738884..130738902
-
Hg19::chr9:130738905..130738929,-p@chr9:130738905..130738929
-
Hg19::chr9:133816046..133816048,-p@chr9:133816046..133816048
-
Hg19::chr9:133816054..133816060,-p@chr9:133816054..133816060
-
Hg19::chr9:133816065..133816079,-p@chr9:133816065..133816079
-
Hg19::chr9:133816081..133816105,-p@chr9:133816081..133816105
-
Hg19::chr9:136467523..136467541,-p@chr9:136467523..136467541
-
Hg19::chr9:136499577..136499584,+p@chr9:136499577..136499584
+
Hg19::chr9:136753424..136753441,-p@chr9:136753424..136753441
-
Hg19::chr9:139940990..139941047,-p4@NPDC1
Hg19::chrX:103810874..103810885,+p1@IL1RAPL2
Hg19::chrX:104100378..104100381,+p@chrX:104100378..104100381
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005737cytoplasm0.00283719973544866
GO:0030141secretory granule0.00283719973544866
GO:0007189G-protein signaling, adenylate cyclase activating pathway0.00283719973544866
GO:0044444cytoplasmic part0.00921918044552319
GO:0000139Golgi membrane0.00921918044552319
GO:0000267cell fraction0.00921918044552319
GO:0005179hormone activity0.00921918044552319
GO:0007188G-protein signaling, coupled to cAMP nucleotide second messenger0.00921918044552319
GO:0044431Golgi apparatus part0.00921918044552319
GO:0019933cAMP-mediated signaling0.00921918044552319
GO:0031410cytoplasmic vesicle0.00921918044552319
GO:0031982vesicle0.00921918044552319
GO:0005625soluble fraction0.00921918044552319
GO:0005794Golgi apparatus0.00921918044552319
GO:0007190adenylate cyclase activation0.0145487135589096
GO:0045087innate immune response0.0145487135589096
GO:0007187G-protein signaling, coupled to cyclic nucleotide second messenger0.0145487135589096
GO:0019935cyclic-nucleotide-mediated signaling0.0145487135589096
GO:0051349positive regulation of lyase activity0.0145487135589096
GO:0045762positive regulation of adenylate cyclase activity0.0145487135589096
GO:0031281positive regulation of cyclase activity0.0145487135589096
GO:0005184neuropeptide hormone activity0.0194955752777347
GO:0022402cell cycle process0.0194955752777347
GO:0008015blood circulation0.0194955752777347
GO:0003013circulatory system process0.0194955752777347
GO:0006936muscle contraction0.0194955752777347
GO:0003012muscle system process0.0194955752777347
GO:0045761regulation of adenylate cyclase activity0.0194955752777347
GO:0042581specific granule0.0194955752777347
GO:0004441inositol-1,4-bisphosphate 1-phosphatase activity0.0194955752777347
GO:0048702embryonic neurocranium morphogenesis0.0194955752777347
GO:0004598peptidylamidoglycolate lyase activity0.0194955752777347
GO:0031716calcitonin receptor binding0.0194955752777347
GO:0004286proprotein convertase 2 activity0.0194955752777347
GO:0001984vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure0.0194955752777347
GO:0042271susceptibility to natural killer cell mediated cytotoxicity0.0194955752777347
GO:0035150regulation of tube size0.0194955752777347
GO:0050880regulation of blood vessel size0.0194955752777347
GO:0051339regulation of lyase activity0.0194955752777347
GO:0031279regulation of cyclase activity0.0194955752777347
GO:0008016regulation of heart contraction0.0194955752777347
GO:0003018vascular process in circulatory system0.0195443769341191
GO:0006486protein amino acid glycosylation0.0195443769341191
GO:0043413biopolymer glycosylation0.0200595991583854
GO:0008375acetylglucosaminyltransferase activity0.0200900194078242
GO:0007154cell communication0.0200900194078242
GO:0009101glycoprotein biosynthetic process0.0200900194078242
GO:0003015heart process0.0200900194078242
GO:0060047heart contraction0.0200900194078242
GO:0012505endomembrane system0.0200900194078242
GO:0005102receptor binding0.0205864393041321
GO:0008146sulfotransferase activity0.0234886471417827
GO:0007165signal transduction0.0248165823120294
GO:0009100glycoprotein metabolic process0.0248165823120294
GO:0051649establishment of cellular localization0.0248165823120294
GO:0043229intracellular organelle0.0248165823120294
GO:0043226organelle0.0248165823120294
GO:0006948induction by virus of cell-cell fusion in host0.0248165823120294
GO:0004910interleukin-1, Type II, blocking receptor activity0.0248165823120294
GO:0001983baroreceptor response to increased systemic arterial blood pressure0.0248165823120294
GO:0019968interleukin-1, Type II, blocking binding0.0248165823120294
GO:0016312inositol bisphosphate phosphatase activity0.0248165823120294
GO:0030144alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity0.0248165823120294
GO:0051641cellular localization0.0248165823120294
GO:0048523negative regulation of cellular process0.025477497950714
GO:0031420alkali metal ion binding0.025477497950714
GO:0016782transferase activity, transferring sulfur-containing groups0.0256829987908073
GO:0045786negative regulation of progression through cell cycle0.0256829987908073
GO:0048519negative regulation of biological process0.0292832235172398
GO:0065002intracellular protein transport across a membrane0.0301046166136714
GO:0007049cell cycle0.0301046166136714
GO:0035313wound healing, spreading of epidermal cells0.0301046166136714
GO:0004504peptidylglycine monooxygenase activity0.0301046166136714
GO:0003829beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity0.0301046166136714
GO:0016808proprotein convertase activity0.0301046166136714
GO:0050961detection of temperature stimulus during sensory perception0.0301046166136714
GO:0050965detection of temperature stimulus during sensory perception of pain0.0301046166136714
GO:0045932negative regulation of muscle contraction0.0301046166136714
GO:0045986negative regulation of smooth muscle contraction0.0301046166136714
GO:0043085positive regulation of catalytic activity0.0309776874453533
GO:0043065positive regulation of apoptosis0.0309776874453533
GO:0043068positive regulation of programmed cell death0.031272145987102
GO:0051606detection of stimulus0.0320111792065642
GO:0019932second-messenger-mediated signaling0.0320111792065642
GO:0035239tube morphogenesis0.0320111792065642
GO:0002028regulation of sodium ion transport0.0320111792065642
GO:0043195terminal button0.0320111792065642
GO:0033267axon part0.0320111792065642
GO:0016048detection of temperature stimulus0.0320111792065642
GO:0050951sensory perception of temperature stimulus0.0320111792065642
GO:0048701embryonic cranial skeleton morphogenesis0.0320111792065642
GO:0003835beta-galactoside alpha-2,6-sialyltransferase activity0.0320111792065642
GO:0007184SMAD protein nuclear translocation0.0320111792065642
GO:0008109N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity0.0320111792065642
GO:0003701RNA polymerase I transcription factor activity0.0320111792065642
GO:0001978carotid sinus baroreceptor feedback regulation of systemic arterial blood pressure0.0320111792065642
GO:0003025baroreceptor regulation of systemic arterial blood pressure0.0320111792065642
GO:0031403lithium ion binding0.0320111792065642
GO:0015016[heparan sulfate]-glucosamine N-sulfotransferase activity0.0320111792065642
GO:0016021integral to membrane0.0327749287978127
GO:0045184establishment of protein localization0.0342165106167176
GO:0031224intrinsic to membrane0.0342165106167176
GO:0044464cell part0.0347920793349787
GO:0006952defense response0.035617442548693
GO:0008467heparin-glucosamine 3-O-sulfotransferase activity0.0369999458837642
GO:0048265response to pain0.0369999458837642
GO:0003085negative regulation of systemic arterial blood pressure0.0369999458837642
GO:0008104protein localization0.038105327651986
GO:0042995cell projection0.0401647866387421
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway0.0412863325297617
GO:0002027regulation of heart rate0.0412863325297617
GO:0001912positive regulation of leukocyte mediated cytotoxicity0.0412863325297617
GO:0051482elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)0.0412863325297617
GO:0045954positive regulation of natural killer cell mediated cytotoxicity0.0412863325297617
GO:0045778positive regulation of ossification0.0412863325297617
GO:0005856cytoskeleton0.0418085846115234
GO:0050794regulation of cellular process0.0424296841742674
GO:0007267cell-cell signaling0.042790728048361
GO:0033036macromolecule localization0.042790728048361
GO:0051049regulation of transport0.04398091260169
GO:0042269regulation of natural killer cell mediated cytotoxicity0.0446444351479221
GO:0031645negative regulation of neurological process0.0446444351479221
GO:0005868cytoplasmic dynein complex0.0446444351479221
GO:0046852positive regulation of bone remodeling0.0446444351479221
GO:0016023cytoplasmic membrane-bound vesicle0.046404432021233
GO:0035295tube development0.0471555423947684
GO:0031988membrane-bound vesicle0.0473811370175228
GO:0000074regulation of progression through cell cycle0.0473811370175228
GO:0048518positive regulation of biological process0.0473811370175228
GO:0045776negative regulation of blood pressure0.0473811370175228
GO:0004908interleukin-1 receptor activity0.0473811370175228
GO:0030279negative regulation of ossification0.0473811370175228
GO:0001976regulation of systemic arterial blood pressure by neurological process0.0473811370175228
GO:0051726regulation of cell cycle0.0473811370175228
GO:0005515protein binding0.0473811370175228
GO:0031090organelle membrane0.048147535383269
GO:0044425membrane part0.0491408776240159



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br><br>disease_data<br>


Disease
Ontology termp-valuen
somatostatinoma4.66e-661
lung small cell carcinoma8.69e-184
neuroendocrine tumor2.74e-126
bronchus cancer8.99e-117
bronchogenic carcinoma8.99e-117
lung carcinoma1.12e-089
neuroectodermal tumor6.56e-0810


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.13.78364e-12
MA0004.10.559702
MA0006.10.0580193
MA0007.10.102577
MA0009.11.78813
MA0014.11.78329e-06
MA0017.10.342658
MA0019.11.23179
MA0024.10.107867
MA0025.10.394897
MA0027.11.1536
MA0028.10.00793547
MA0029.10.257037
MA0030.12.50866
MA0031.12.00437
MA0038.10.0184211
MA0040.10.128944
MA0041.10.364024
MA0042.10.365892
MA0043.10.0184883
MA0046.10.197984
MA0048.10.460736
MA0050.10.0345077
MA0051.10.706746
MA0052.10.272178
MA0055.13.72153
MA0056.10
MA0057.10.00856762
MA0058.10.468473
MA0059.10.736045
MA0060.10.139175
MA0061.10.086592
MA0063.10
MA0066.10.730072
MA0067.10.362202
MA0068.10.229239
MA0069.10.19367
MA0070.10.0148776
MA0071.12.30965
MA0072.12.05901
MA0073.10.000477995
MA0074.10.152853
MA0076.10.0648658
MA0077.10.562791
MA0078.10.538809
MA0081.10.259167
MA0083.10.0870687
MA0084.11.14826
MA0087.11.21119
MA0088.10.240856
MA0089.10
MA0090.10.0257873
MA0091.10.73947
MA0092.11.4878
MA0093.10.851641
MA0095.10
MA0098.10
MA0100.10.0225669
MA0101.10.0123577
MA0103.19.11696
MA0105.10.0083636
MA0106.10.367331
MA0107.10.026509
MA0108.21.98133
MA0109.10
MA0111.10.910788
MA0113.10.273798
MA0114.10.084483
MA0115.10.0809316
MA0116.10.198038
MA0117.10.104966
MA0119.10.058282
MA0122.10.291109
MA0124.11.31087
MA0125.11.44956
MA0130.10
MA0131.10.00113568
MA0132.10
MA0133.10
MA0135.10.100479
MA0136.11.23571
MA0139.10.10825
MA0140.10.908084
MA0141.10.452249
MA0142.10.580585
MA0143.10.803288
MA0144.13.10044
MA0145.10.734457
MA0146.14.16644e-06
MA0147.10.112872
MA0148.13.18546
MA0149.10.00224719
MA0062.20.0350445
MA0035.20.263234
MA0039.20.00378608
MA0138.20.0619275
MA0002.20.180278
MA0137.21.22879
MA0104.20.136427
MA0047.20.881478
MA0112.20.143379
MA0065.20.148731
MA0150.10.182402
MA0151.10
MA0152.10.183225
MA0153.10.341438
MA0154.10.0972809
MA0155.10.0837171
MA0156.12.4178
MA0157.11.25074
MA0158.10
MA0159.12.76806
MA0160.11.21236
MA0161.10
MA0162.15.33483e-08
MA0163.14.08873e-06
MA0164.10.455341
MA0080.21.38272
MA0018.20.371332
MA0099.20.95231
MA0079.24.24304e-15
MA0102.20.236057
MA0258.11.94283
MA0259.10.186857
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
FOXA1#3169291.623036225920090.006579245404170410.0281126671616952
SUZ12#23512102.531100046013280.006852546776686150.0290416399306223



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data