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Revision as of 17:17, 15 June 2012

Name:otic placode
Definition:"A cranial placode which, once specified, invaginates to form an otic cup, which eventually separates from the surface ectoderm to form the otic vesicle or otocyst, a rounded structure without appar- ent polarity. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII" [NBK:NBK53175]
Xrefs:
links:

AAO:0011079
EFO:0003429
EHDAA:506
EHDAA2:0001339
EMAPA:16195
ncithesaurus:Otic_Placodes
TAO:0000138
VHOG:0000235
XAO:0000223

ZFA:0000138
Synonyms: "auditory placode" RELATED []
"ear placode" RELATED []
"ear/otic placode" RELATED []
Comments:With the exception of the pigment cells of the stria vascularis and the secretory epithelium of the cochlea, which are of neural crest origin, all compo- nents of the inner ear derive from the otic placode. In most species the thickening of the ectoderm into a placode occurs in a region adjacent to rhombomere 5 (reviewed in Ohyama et al., 2007), while in amphibians the otic placode is centered onto rhombomere 4 (Ruiz i Altaba and Jessell, 1991).[NBK53175]
Alt_id: UBERON:XAO_0000223-ZFA_0000138
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0003067(dorsolateral placode),UBERON:0005085(ectodermal placode)
part_of:UBERON:0001690(ear)



Children

develops from:UBERON:0009123 (otic cup)
part of:UBERON:0003249 (epithelium of otic placode)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology



Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0003069 (otic placode), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.87e-86FFCP PHASE2:Mm9::chr4:63079735..63079745,-#_79a6708211b885bd34d9bea04e5ffea8p@chr4:63079735..63079745, -
1.87e-86FFCP PHASE2:Mm9::chr5:147854240..147854249,-#_79a6708211b885bd34d9bea04e5ffea8p@chr5:147854240..147854249, -
1.87e-86FFCP PHASE2:Mm9::chr10:107349430..107349440,-#_79a6708211b885bd34d9bea04e5ffea8p3@Otogl
1.87e-86FFCP PHASE1:Mm9::chr18:81314626..81314636,+#_79a6708211b885bd34d9bea04e5ffea8p@chr18:81314626..81314636, +
1.87e-86FFCP PHASE2:Mm9::chr17:31335903..31335921,-#_79a6708211b885bd34d9bea04e5ffea8p2@Tmprss3
1.87e-86FFCP PHASE2:Mm9::chr14:47293496..47293510,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:47293496..47293510, -
1.87e-86FFCP PHASE1:Mm9::chr9:42208142..42208157,-#_79a6708211b885bd34d9bea04e5ffea8p10@Tecta
1.87e-86FFCP PHASE1:Mm9::chr13:37195838..37195870,-#_79a6708211b885bd34d9bea04e5ffea8p@chr13:37195838..37195870, -
1.87e-86FFCP PHASE2:Mm9::chr6:86746562..86746579,-#_79a6708211b885bd34d9bea04e5ffea8p@chr6:86746562..86746579, -
1.87e-86FFCP PHASE2:Mm9::chr15:58480061..58480066,+#_79a6708211b885bd34d9bea04e5ffea8p5@Fer1l6
1.87e-86FFCP PHASE2:Mm9::chr9:42207777..42207789,-#_79a6708211b885bd34d9bea04e5ffea8p7@Tecta
1.87e-86FFCP PHASE1:Mm9::chr13:76964459..76964469,+#_79a6708211b885bd34d9bea04e5ffea8p15@Mctp1
1.87e-86FFCP PHASE1:Mm9::chr3:58626291..58626298,-#_79a6708211b885bd34d9bea04e5ffea8p@chr3:58626291..58626298, -
1.87e-86FFCP PHASE1:Mm9::chr7:133957514..133957529,+#_79a6708211b885bd34d9bea04e5ffea8p@chr7:133957514..133957529, +
1.87e-86FFCP PHASE1:Mm9::chr12:13508046..13508055,+#_79a6708211b885bd34d9bea04e5ffea8p@chr12:13508046..13508055, +
1.87e-86FFCP PHASE1:Mm9::chr4:115556972..115556979,+#_79a6708211b885bd34d9bea04e5ffea8p3@Kncn
1.87e-86FFCP PHASE1:Mm9::chr16:45693840..45693856,-#_79a6708211b885bd34d9bea04e5ffea8p1@Tmprss7
1.87e-86FFCP PHASE2:Mm9::chr8:13414266..13414279,+#_79a6708211b885bd34d9bea04e5ffea8p@chr8:13414266..13414279, +
1.87e-86FFCP PHASE2:Mm9::chr2:53464168..53464175,+#_79a6708211b885bd34d9bea04e5ffea8p@chr2:53464168..53464175, +
1.87e-86FFCP PHASE2:Mm9::chr5:72652660..72652667,+#_79a6708211b885bd34d9bea04e5ffea8p@chr5:72652660..72652667, +
1.87e-86FFCP PHASE2:Mm9::chr11:89702580..89702593,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:89702580..89702593, -
1.87e-86FFCP PHASE1:Mm9::chr9:42207777..42207789,-#_79a6708211b885bd34d9bea04e5ffea8p7@Tecta
1.87e-86FFCP PHASE2:Mm9::chr2:136942131..136942142,-#_79a6708211b885bd34d9bea04e5ffea8p6@Jag1
1.87e-86FFCP PHASE1:Mm9::chr19:4140290..4140321,+#_79a6708211b885bd34d9bea04e5ffea8p2@Gpr152
1.87e-86FFCP PHASE1:Mm9::chr11:11599532..11599539,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:11599532..11599539, -
1.87e-86FFCP PHASE1:Mm9::chr10:107349309..107349318,-#_79a6708211b885bd34d9bea04e5ffea8p4@Otogl
1.87e-86FFCP PHASE2:Mm9::chr11:114603036..114603048,+#_79a6708211b885bd34d9bea04e5ffea8p@chr11:114603036..114603048, +
1.87e-86FFCP PHASE2:Mm9::chr16:93971325..93971337,-#_79a6708211b885bd34d9bea04e5ffea8p@chr16:93971325..93971337, -
1.87e-86FFCP PHASE2:Mm9::chr1:154246932..154246939,+#_79a6708211b885bd34d9bea04e5ffea8p7@Glt25d2
1.87e-86FFCP PHASE1:Mm9::chr5:3909310..3909321,+#_79a6708211b885bd34d9bea04e5ffea8p@chr5:3909310..3909321, +
1.87e-86FFCP PHASE1:Mm9::chr1:43454162..43454170,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:43454162..43454170, -
1.87e-86FFCP PHASE2:Mm9::chr8:13435173..13435186,+#_79a6708211b885bd34d9bea04e5ffea8p6@Fam70b
1.87e-86FFCP PHASE2:Mm9::chr2:121206667..121206674,-#_79a6708211b885bd34d9bea04e5ffea8p2@Strc
1.87e-86FFCP PHASE1:Mm9::chr17:27252925..27252939,+#_79a6708211b885bd34d9bea04e5ffea8p@chr17:27252925..27252939, +
1.87e-86FFCP PHASE2:Mm9::chr10:81091447..81091464,+#_79a6708211b885bd34d9bea04e5ffea8p9@Ankrd24
1.87e-86FFCP PHASE2:Mm9::chr1:78523144..78523177,+#_79a6708211b885bd34d9bea04e5ffea8p@chr1:78523144..78523177, +
1.87e-86FFCP PHASE2:Mm9::chr7:53496326..53496340,+#_79a6708211b885bd34d9bea04e5ffea8p1@Otog
1.87e-86FFCP PHASE2:Mm9::chr5:3909310..3909321,+#_79a6708211b885bd34d9bea04e5ffea8p@chr5:3909310..3909321, +
1.87e-86FFCP PHASE2:Mm9::chr14:31283072..31283081,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:31283072..31283081, -
1.87e-86FFCP PHASE2:Mm9::chr11:75421384..75421397,+#_79a6708211b885bd34d9bea04e5ffea8p@chr11:75421384..75421397, +
1.87e-86FFCP PHASE2:Mm9::chr19:4140290..4140321,+#_79a6708211b885bd34d9bea04e5ffea8p2@Gpr152
1.87e-86FFCP PHASE1:Mm9::chr4:133802857..133802884,+#_79a6708211b885bd34d9bea04e5ffea8p@chr4:133802857..133802884, +
1.87e-86FFCP PHASE1:Mm9::chr19:10536797..10536802,-#_79a6708211b885bd34d9bea04e5ffea8p@chr19:10536797..10536802, -
1.87e-86FFCP PHASE1:Mm9::chr17:13983160..13983167,+#_79a6708211b885bd34d9bea04e5ffea8p@chr17:13983160..13983167, +
1.87e-86FFCP PHASE2:Mm9::chr6:30619443..30619450,-#_79a6708211b885bd34d9bea04e5ffea8p13@Tsga14
1.87e-86FFCP PHASE1:Mm9::chr3:100724698..100724706,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:100724698..100724706, +
1.87e-86FFCP PHASE2:Mm9::chr2:67011921..67011934,+#_79a6708211b885bd34d9bea04e5ffea8p2@Gm1322
1.87e-86FFCP PHASE2:Mm9::chr9:42207965..42207978,-#_79a6708211b885bd34d9bea04e5ffea8p5@Tecta
1.87e-86FFCP PHASE1:Mm9::chr8:13435173..13435186,+#_79a6708211b885bd34d9bea04e5ffea8p6@Fam70b
1.87e-86FFCP PHASE1:Mm9::chr13:78322383..78322395,-#_79a6708211b885bd34d9bea04e5ffea8p2@uc007rhb.1
1.87e-86FFCP PHASE2:Mm9::chr1:172843847..172843880,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:172843847..172843880, -
1.87e-86FFCP PHASE1:Mm9::chr1:182528388..182528403,+#_79a6708211b885bd34d9bea04e5ffea8p@chr1:182528388..182528403, +
1.87e-86FFCP PHASE2:Mm9::chr3:81012915..81012923,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:81012915..81012923, +
1.87e-86FFCP PHASE2:Mm9::chr10:107349309..107349318,-#_79a6708211b885bd34d9bea04e5ffea8p4@Otogl
1.87e-86FFCP PHASE1:Mm9::chr5:68423014..68423037,+#_79a6708211b885bd34d9bea04e5ffea8p1@Grxcr1
1.87e-86FFCP PHASE1:Mm9::chr18:66033526..66033539,-#_79a6708211b885bd34d9bea04e5ffea8p@chr18:66033526..66033539, -
1.87e-86FFCP PHASE1:Mm9::chr16:93971357..93971363,-#_79a6708211b885bd34d9bea04e5ffea8p@chr16:93971357..93971363, -
1.87e-86FFCP PHASE2:Mm9::chr17:13983179..13983190,+#_79a6708211b885bd34d9bea04e5ffea8p@chr17:13983179..13983190, +
1.87e-86FFCP PHASE1:Mm9::chr9:42207965..42207978,-#_79a6708211b885bd34d9bea04e5ffea8p5@Tecta
1.87e-86FFCP PHASE2:Mm9::chr9:42206784..42206793,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:42206784..42206793, -
1.87e-86FFCP PHASE2:Mm9::chr19:55255289..55255299,+#_79a6708211b885bd34d9bea04e5ffea8p2@Tectb
1.87e-86FFCP PHASE2:Mm9::chr5:21371424..21371435,-#_79a6708211b885bd34d9bea04e5ffea8p2@Slc26a5
1.87e-86FFCP PHASE2:Mm9::chr11:120222470..120222516,+#_79a6708211b885bd34d9bea04e5ffea8p2@Fscn2
1.87e-86FFCP PHASE1:Mm9::chr3:35012425..35012439,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:35012425..35012439, +
1.87e-86FFCP PHASE1:Mm9::chr15:89215319..89215330,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:89215319..89215330, +
1.87e-86FFCP PHASE2:Mm9::chr11:102123554..102123566,+#_79a6708211b885bd34d9bea04e5ffea8p4@BC030867
1.87e-86FFCP PHASE2:Mm9::chr5:28035962..28035983,+#_79a6708211b885bd34d9bea04e5ffea8p@chr5:28035962..28035983, +
1.87e-86FFCP PHASE1:Mm9::chr1:172843796..172843799,-#_79a6708211b885bd34d9bea04e5ffea8p@chr1:172843796..172843799, -
1.87e-86FFCP PHASE1:Mm9::chr9:42206784..42206793,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:42206784..42206793, -
1.87e-86FFCP PHASE1:Mm9::chr2:67011941..67011951,+#_79a6708211b885bd34d9bea04e5ffea8p3@Gm1322
1.87e-86FFCP PHASE2:Mm9::chr1:93235228..93235249,+#_79a6708211b885bd34d9bea04e5ffea8p@chr1:93235228..93235249, +
1.87e-86FFCP PHASE2:Mm9::chr15:12848147..12848162,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:12848147..12848162, +
1.87e-86FFCP PHASE1:Mm9::chr4:154208086..154208123,+#_79a6708211b885bd34d9bea04e5ffea8p@chr4:154208086..154208123, +
1.87e-86FFCP PHASE1:Mm9::chr17:31335903..31335921,-#_79a6708211b885bd34d9bea04e5ffea8p2@Tmprss3
1.87e-86FFCP PHASE1:Mm9::chr11:114603036..114603048,+#_79a6708211b885bd34d9bea04e5ffea8p@chr11:114603036..114603048, +
1.87e-86FFCP PHASE1:Mm9::chr3:154459184..154459195,+#_79a6708211b885bd34d9bea04e5ffea8p@chr3:154459184..154459195, +
1.87e-86FFCP PHASE2:Mm9::chr13:78257518..78257522,+#_79a6708211b885bd34d9bea04e5ffea8p@chr13:78257518..78257522, +
1.87e-86FFCP PHASE2:Mm9::chr1:16651649..16651655,+#_79a6708211b885bd34d9bea04e5ffea8p@chr1:16651649..16651655, +
1.87e-86FFCP PHASE1:Mm9::chr14:102297728..102297742,+#_79a6708211b885bd34d9bea04e5ffea8p@chr14:102297728..102297742, +
1.87e-86FFCP PHASE2:Mm9::chr2:29935952..29935993,+#_79a6708211b885bd34d9bea04e5ffea8p7@Pkn3
1.87e-86FFCP PHASE1:Mm9::chr5:30710416..30710440,-#_79a6708211b885bd34d9bea04e5ffea8p2@Otof
1.87e-86FFCP PHASE1:Mm9::chr14:47293496..47293510,-#_79a6708211b885bd34d9bea04e5ffea8p@chr14:47293496..47293510, -
1.87e-86FFCP PHASE2:Mm9::chr2:9811162..9811171,-#_79a6708211b885bd34d9bea04e5ffea8p2@9230102O04Rik
1.87e-86FFCP PHASE2:Mm9::chr14:102297728..102297742,+#_79a6708211b885bd34d9bea04e5ffea8p@chr14:102297728..102297742, +
1.87e-86FFCP PHASE1:Mm9::chr9:50968647..50968668,-#_79a6708211b885bd34d9bea04e5ffea8p@chr9:50968647..50968668, -
1.87e-86FFCP PHASE2:Mm9::chr11:8405038..8405048,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:8405038..8405048, -
1.87e-86FFCP PHASE1:Mm9::chr11:4689837..4689845,-#_79a6708211b885bd34d9bea04e5ffea8p@chr11:4689837..4689845, -
1.87e-86FFCP PHASE2:Mm9::chr7:109265277..109265288,-#_79a6708211b885bd34d9bea04e5ffea8p4@Chrna10
1.87e-86FFCP PHASE2:Mm9::chr19:21028739..21028785,-#_79a6708211b885bd34d9bea04e5ffea8p1@Tmc1
1.87e-86FFCP PHASE1:Mm9::chr18:81327205..81327211,+#_79a6708211b885bd34d9bea04e5ffea8p@chr18:81327205..81327211, +
1.87e-86FFCP PHASE2:Mm9::chr17:31335953..31335957,-#_79a6708211b885bd34d9bea04e5ffea8p3@Tmprss3
1.87e-86FFCP PHASE2:Mm9::chr9:42207792..42207805,-#_79a6708211b885bd34d9bea04e5ffea8p11@Tecta
1.87e-86FFCP PHASE1:Mm9::chr8:13414266..13414279,+#_79a6708211b885bd34d9bea04e5ffea8p@chr8:13414266..13414279, +
1.87e-86FFCP PHASE1:Mm9::chr13:78257454..78257465,+#_79a6708211b885bd34d9bea04e5ffea8p@chr13:78257454..78257465, +
1.87e-86FFCP PHASE2:Mm9::chr15:89215306..89215315,+#_79a6708211b885bd34d9bea04e5ffea8p@chr15:89215306..89215315, +
1.87e-86FFCP PHASE2:Mm9::chr7:109052262..109052291,-#_79a6708211b885bd34d9bea04e5ffea8p1@Tomt
1.87e-86FFCP PHASE2:Mm9::chr5:30710403..30710406,-#_79a6708211b885bd34d9bea04e5ffea8p10@Otof
1.87e-86FFCP PHASE1:Mm9::chr14:20649897..20649907,+#_79a6708211b885bd34d9bea04e5ffea8p@chr14:20649897..20649907, +
1.87e-86FFCP PHASE1:Mm9::chr12:13572961..13572974,+#_79a6708211b885bd34d9bea04e5ffea8p@chr12:13572961..13572974, +
1.87e-86FFCP PHASE1:Mm9::chr4:115556989..115556997,+#_79a6708211b885bd34d9bea04e5ffea8p1@Kncn

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