Coexpression cluster:C281: Difference between revisions
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| ||
|tfbs_overrepresentation_for_novel_motifs=2.06838,0.411041,1.57671,0.174261,0.00824124,0.1727,1.37223,0.420694,0.599858,3.50219,1.83527,0.301982,0.156509,1.32536,0.042025,0.144816,1.03941,0.0223264,0.184198,0.0472946,0.0637904,0.270182,3.11215,0.114952,1.88617,0.329864,0.115643,1.46503,0.688437,0.535745,1.26138,0.599518,1.70305,0.582932,0.793485,0.0488927,3.6161,1.51968,0.0648498,0.51279,0.186888,0.815878,0.107738,0.0413584,1.77571,0.663462,0.917582,0.914992,0.0129972,0.688952,1.16605,1.42514,0.323039,1.32632,0.373267,1.33728,0.128332,0.791419,0.535062,2.81861,0.662967,1.91761,0.261975,0.971946,2.62322,1.42971,0.444327,0.768402,0.201596,1.50568,1.12341,0.163513,4.20298,0.3717,2.18601,1.68264,0.174357,0.479271,0.199539,0.0199273,0.476111,0.969355,0.0804887,0.00863138,2.40797,3.92506,0.315374,0.358033,1.82101,0.860953,0.522821,4.15269,0.219125,0.00249229,0.438554,0.138889,0.0980355,1.98247,0.122374,0.415641,0.065868,0.215435,1.26704,0.549584,0.862665,4.82052,1.60047,0.869239,1.44182,0.885539,0.18314,0.678866,0.16189,0.635079,0.482063,0.181356,2.66908,1.69857,1.42181,0.00262013,0.365229,0.118792,0.170099,0.288769,0.577125,0.933171,0.0694627,1.18546,0.398874,2.31443,0.312344,0.305407,0.410414,0.284832,0.533887,0.0137169,0.121932,0.666354,3.18104,1.29861,0.910351,0.466265,0.0701331,0.245272,0.866781,0.438861,0.418045,1.14349,0.111271,1.07823,1.06909,5.0326,0.840233,0.77635,0.542504,0.648552,0.360413,0.0068826,0.0926062,1.69044,1.17501,0.809457,0.199042,1.29954,0.463413,0.274611,0.198112,0.0714183,2.75627 | |tfbs_overrepresentation_for_novel_motifs=2.06838,0.411041,1.57671,0.174261,0.00824124,0.1727,1.37223,0.420694,0.599858,3.50219,1.83527,0.301982,0.156509,1.32536,0.042025,0.144816,1.03941,0.0223264,0.184198,0.0472946,0.0637904,0.270182,3.11215,0.114952,1.88617,0.329864,0.115643,1.46503,0.688437,0.535745,1.26138,0.599518,1.70305,0.582932,0.793485,0.0488927,3.6161,1.51968,0.0648498,0.51279,0.186888,0.815878,0.107738,0.0413584,1.77571,0.663462,0.917582,0.914992,0.0129972,0.688952,1.16605,1.42514,0.323039,1.32632,0.373267,1.33728,0.128332,0.791419,0.535062,2.81861,0.662967,1.91761,0.261975,0.971946,2.62322,1.42971,0.444327,0.768402,0.201596,1.50568,1.12341,0.163513,4.20298,0.3717,2.18601,1.68264,0.174357,0.479271,0.199539,0.0199273,0.476111,0.969355,0.0804887,0.00863138,2.40797,3.92506,0.315374,0.358033,1.82101,0.860953,0.522821,4.15269,0.219125,0.00249229,0.438554,0.138889,0.0980355,1.98247,0.122374,0.415641,0.065868,0.215435,1.26704,0.549584,0.862665,4.82052,1.60047,0.869239,1.44182,0.885539,0.18314,0.678866,0.16189,0.635079,0.482063,0.181356,2.66908,1.69857,1.42181,0.00262013,0.365229,0.118792,0.170099,0.288769,0.577125,0.933171,0.0694627,1.18546,0.398874,2.31443,0.312344,0.305407,0.410414,0.284832,0.533887,0.0137169,0.121932,0.666354,3.18104,1.29861,0.910351,0.466265,0.0701331,0.245272,0.866781,0.438861,0.418045,1.14349,0.111271,1.07823,1.06909,5.0326,0.840233,0.77635,0.542504,0.648552,0.360413,0.0068826,0.0926062,1.69044,1.17501,0.809457,0.199042,1.29954,0.463413,0.274611,0.198112,0.0714183,2.75627 | ||
|tfbs_overrepresentation_jaspar=MA0003.1;6.96095,MA0004.1;0.623722,MA0006.1;1.67221,MA0007.1;0.904552,MA0009.1;0.282049,MA0014.1;6.33056,MA0017.1;0.163868,MA0019.1;0.637656,MA0024.1;8.18149,MA0025.1;0.383675,MA0027.1;1.77546,MA0028.1;2.71532,MA0029.1;0.222602,MA0030.1;0.215031,MA0031.1;0.174316,MA0038.1;3.15106,MA0040.1;0.226506,MA0041.1;0.0434336,MA0042.1;0.0344066,MA0043.1;0.282278,MA0046.1;0.274202,MA0048.1;0.0855519,MA0050.1;0.324596,MA0051.1;0.0713589,MA0052.1;0.2291,MA0055.1;0.0982142,MA0056.1;0,MA0057.1;0.210418,MA0058.1;0.633056,MA0059.1;0.0757992,MA0060.1;26.4223,MA0061.1;0.190797,MA0063.1;0,MA0066.1;0.924061,MA0067.1;0.537012,MA0068.1;0.110487,MA0069.1;0.746822,MA0070.1;1.34024,MA0071.1;0.212157,MA0072.1;0.260306,MA0073.1;3.17614,MA0074.1;0.248986,MA0076.1;1.83077,MA0077.1;0.254892,MA0078.1;0.371676,MA0081.1;0.38039,MA0083.1;0.287504,MA0084.1;0.703837,MA0087.1;0.258584,MA0088.1;1.33508,MA0089.1;0,MA0090.1;0.0971665,MA0091.1;0.350729,MA0092.1;0.119932,MA0093.1;1.31245,MA0095.1;0,MA0098.1;0,MA0100.1;1.98721,MA0101.1;0.259452,MA0103.1;0.108723,MA0105.1;0.655342,MA0106.1;0.303356,MA0107.1;0.253705,MA0108.2;0.172469,MA0109.1;0,MA0111.1;0.26112,MA0113.1;0.0981023,MA0114.1;0.241927,MA0115.1;0.471806,MA0116.1;0.261874,MA0117.1;0.83365,MA0119.1;2.04178,MA0122.1;0.329219,MA0124.1;0.437263,MA0125.1;0.36951,MA0130.1;0,MA0131.1;0.790153,MA0132.1;0,MA0133.1;0,MA0135.1;0.304312,MA0136.1;0.262713,MA0139.1;2.28907,MA0140.1;0.0574137,MA0141.1;0.192805,MA0142.1;0.155551,MA0143.1;0.0981847,MA0144.1;0.0453363,MA0145.1;1.29506,MA0146.1;3.78728,MA0147.1;1.56199,MA0148.1;0.0453767,MA0149.1;1.64974,MA0062.2;3.64086,MA0035.2;0.0571647,MA0039.2;6.75105,MA0138.2;0.11686,MA0002.2;0.229858,MA0137.2;0.0526133,MA0104.2;1.70965,MA0047.2;0.0852269,MA0112.2;0.266225,MA0065.2;0.1479,MA0150.1;0.0929679,MA0151.1;0,MA0152.1;0.472076,MA0153.1;0.356306,MA0154.1;1.23683,MA0155.1;0.443381,MA0156.1;0.505588,MA0157.1;0.140121,MA0158.1;0,MA0159.1;0.444017,MA0160.1;0.187803,MA0161.1;0,MA0162.1;2.66971,MA0163.1;2.33408,MA0164.1;0.103984,MA0080.2;0.440272,MA0018.2;0.632229,MA0099.2;0.0598901,MA0079.2;2.9434,MA0102.2;0.737926,MA0258.1;0.0396648,MA0259.1;1.63407,MA0442.1;0 | |||
}} | }} |
Revision as of 18:58, 22 January 2013
Full id: C281_Hodgkin_Reticulocytes_chronic_NK_acute_retinoblastoma_small
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
p.value | FDR | nGenes | nPathway | Name |
---|---|---|---|---|
1.73178102544466e-09 | 1.82702898184412e-07 | 5 | 36 | DNA replication (KEGG):03030 |
1.10325843968138e-06 | 7.75958435909238e-05 | 5 | 128 | Cell cycle (KEGG):04110 |
1.90743271438225e-07 | 1.50925613525496e-05 | 5 | 90 | Cell cycle (Wikipathways):WP179 |
4.98652049775905e-08 | 4.50923925011639e-06 | 5 | 69 | G1 to S cell cycle control (Wikipathways):WP45 |
3.02355555239963e-11 | 4.78477666167241e-09 | 6 | 42 | DNA Replication (Wikipathways):WP1806 |
3.24591931887469e-10 | 4.10933385769536e-08 | 7 | 117 | Cell Cycle Checkpoints (Reactome):REACT_1538 |
9.80048795126114e-19 | 2.0679029577161e-16 | 13 | 200 | DNA Replication (Reactome):REACT_383 |
4.12598982903211e-23 | 1.30587578088866e-20 | 17 | 315 | Cell Cycle, Mitotic (Reactome):REACT_152 |
4.59313990527007e-06 | 0.000290745756003595 | 4 | 77 | Chromosome Maintenance (Reactome):REACT_22172 |
1.45366014094568e-05 | 0.000836515335653285 | 5 | 217 | IL-4 up reg. targets (Netpath):NetPath_16 |
3.21151604202121e-24 | 2.03288965459943e-21 | 18 | 346 | {CDC2,351} (Static Module):NA |
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0007049 | cell cycle | 2.2622870125023e-16 |
GO:0005634 | nucleus | 4.23132874348546e-16 |
GO:0000278 | mitotic cell cycle | 4.23132874348546e-16 |
GO:0007067 | mitosis | 4.73789433253988e-16 |
GO:0000087 | M phase of mitotic cell cycle | 5.12106063799647e-16 |
GO:0022403 | cell cycle phase | 1.06305146223658e-15 |
GO:0000279 | M phase | 5.36970925071529e-15 |
GO:0044427 | chromosomal part | 1.54973723668964e-14 |
GO:0005694 | chromosome | 8.60797535452794e-14 |
GO:0022402 | cell cycle process | 5.66852759063077e-13 |
GO:0006260 | DNA replication | 1.03837854370626e-12 |
GO:0051301 | cell division | 1.05783228862849e-12 |
GO:0006259 | DNA metabolic process | 1.46945657366705e-10 |
GO:0043231 | intracellular membrane-bound organelle | 1.66140932120097e-09 |
GO:0043227 | membrane-bound organelle | 1.66140932120097e-09 |
GO:0044424 | intracellular part | 1.3146869847198e-08 |
GO:0043232 | intracellular non-membrane-bound organelle | 8.2588349448905e-08 |
GO:0043228 | non-membrane-bound organelle | 8.2588349448905e-08 |
GO:0043229 | intracellular organelle | 1.19354022890078e-07 |
GO:0043226 | organelle | 1.19354022890078e-07 |
GO:0005622 | intracellular | 1.66797348673978e-07 |
GO:0000775 | chromosome, pericentric region | 2.09800396016375e-07 |
GO:0006270 | DNA replication initiation | 8.34699349280514e-07 |
GO:0044446 | intracellular organelle part | 1.14054474853553e-06 |
GO:0044422 | organelle part | 1.14054474853553e-06 |
GO:0005515 | protein binding | 2.15921584624533e-06 |
GO:0007059 | chromosome segregation | 4.82429953233651e-06 |
GO:0000785 | chromatin | 9.46384353276404e-06 |
GO:0051276 | chromosome organization and biogenesis | 1.06858606676366e-05 |
GO:0005819 | spindle | 1.34265301171587e-05 |
GO:0008094 | DNA-dependent ATPase activity | 1.66799956858821e-05 |
GO:0006996 | organelle organization and biogenesis | 1.76202849550051e-05 |
GO:0051325 | interphase | 2.16802053167748e-05 |
GO:0000070 | mitotic sister chromatid segregation | 3.08816827560101e-05 |
GO:0000819 | sister chromatid segregation | 3.34379228715376e-05 |
GO:0005657 | replication fork | 4.40378841206214e-05 |
GO:0006974 | response to DNA damage stimulus | 4.81360124306943e-05 |
GO:0006139 | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.000108722617716028 |
GO:0009719 | response to endogenous stimulus | 0.000117470101438644 |
GO:0043283 | biopolymer metabolic process | 0.000167176629529225 |
GO:0006261 | DNA-dependent DNA replication | 0.000192833643950437 |
GO:0000074 | regulation of progression through cell cycle | 0.000216788887620517 |
GO:0051726 | regulation of cell cycle | 0.000229491532198212 |
GO:0044454 | nuclear chromosome part | 0.000339765109271521 |
GO:0051329 | interphase of mitotic cell cycle | 0.000676580578926927 |
GO:0007076 | mitotic chromosome condensation | 0.000750958522993768 |
GO:0042393 | histone binding | 0.000750958522993768 |
GO:0033261 | regulation of progression through S phase | 0.000750958522993768 |
GO:0006268 | DNA unwinding during replication | 0.000840195654269063 |
GO:0000228 | nuclear chromosome | 0.000957776371677201 |
GO:0032508 | DNA duplex unwinding | 0.00100818016843514 |
GO:0032392 | DNA geometric change | 0.00100818016843514 |
GO:0015630 | microtubule cytoskeleton | 0.00103930445808119 |
GO:0051320 | S phase | 0.00130583703614917 |
GO:0030261 | chromosome condensation | 0.00130583703614917 |
GO:0005874 | microtubule | 0.00139015296694561 |
GO:0003682 | chromatin binding | 0.00141128873301318 |
GO:0031570 | DNA integrity checkpoint | 0.00221916089286448 |
GO:0043234 | protein complex | 0.00225183398328797 |
GO:0044464 | cell part | 0.00296865886201738 |
GO:0000910 | cytokinesis | 0.003119778122116 |
GO:0006334 | nucleosome assembly | 0.00497338741349375 |
GO:0000797 | condensin core heterodimer | 0.0055477277281626 |
GO:0042555 | MCM complex | 0.0055477277281626 |
GO:0016043 | cellular component organization and biogenesis | 0.0055477277281626 |
GO:0006325 | establishment and/or maintenance of chromatin architecture | 0.0055477277281626 |
GO:0006323 | DNA packaging | 0.00573896838337752 |
GO:0031497 | chromatin assembly | 0.00624707207923037 |
GO:0006950 | response to stress | 0.00625642725097969 |
GO:0000075 | cell cycle checkpoint | 0.00736081192008598 |
GO:0042623 | ATPase activity, coupled | 0.00927002131673787 |
GO:0006335 | DNA replication-dependent nucleosome assembly | 0.00975672228502966 |
GO:0008054 | cyclin catabolic process | 0.00975672228502966 |
GO:0007088 | regulation of mitosis | 0.00982138043682869 |
GO:0044430 | cytoskeletal part | 0.00982138043682869 |
GO:0006333 | chromatin assembly or disassembly | 0.0119665280658995 |
GO:0065004 | protein-DNA complex assembly | 0.0129432942435279 |
GO:0007080 | mitotic metaphase plate congression | 0.0131832376806434 |
GO:0005721 | centric heterochromatin | 0.0131832376806434 |
GO:0000796 | condensin complex | 0.0131832376806434 |
GO:0008278 | cohesin complex | 0.0131832376806434 |
GO:0016887 | ATPase activity | 0.0150837754738875 |
GO:0032991 | macromolecular complex | 0.0158122035536006 |
GO:0007017 | microtubule-based process | 0.0158122035536006 |
GO:0004844 | uracil DNA N-glycosylase activity | 0.0158122035536006 |
GO:0051310 | metaphase plate congression | 0.0158122035536006 |
GO:0001833 | inner cell mass cell proliferation | 0.0158122035536006 |
GO:0051319 | G2 phase | 0.0158122035536006 |
GO:0000085 | G2 phase of mitotic cell cycle | 0.0158122035536006 |
GO:0031536 | positive regulation of exit from mitosis | 0.0158122035536006 |
GO:0044428 | nuclear part | 0.0179596894477362 |
GO:0051322 | anaphase | 0.0179596894477362 |
GO:0000090 | mitotic anaphase | 0.0179596894477362 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 0.0179596894477362 |
GO:0045120 | pronucleus | 0.0179596894477362 |
GO:0031571 | G1 DNA damage checkpoint | 0.0179596894477362 |
GO:0003688 | DNA replication origin binding | 0.0179596894477362 |
GO:0016728 | oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor | 0.0179596894477362 |
GO:0004748 | ribonucleoside-diphosphate reductase activity | 0.0179596894477362 |
GO:0003689 | DNA clamp loader activity | 0.019930611063397 |
GO:0001832 | blastocyst growth | 0.019930611063397 |
GO:0000076 | DNA replication checkpoint | 0.019930611063397 |
GO:0033170 | DNA-protein loading ATPase activity | 0.019930611063397 |
GO:0051303 | establishment of chromosome localization | 0.019930611063397 |
GO:0050000 | chromosome localization | 0.019930611063397 |
GO:0032297 | negative regulation of DNA replication initiation | 0.019930611063397 |
GO:0005678 | chromatin assembly complex | 0.019930611063397 |
GO:0000808 | origin recognition complex | 0.0224481117831134 |
GO:0005664 | nuclear origin of replication recognition complex | 0.0224481117831134 |
GO:0005663 | DNA replication factor C complex | 0.0224481117831134 |
GO:0006281 | DNA repair | 0.0224481117831134 |
GO:0043170 | macromolecule metabolic process | 0.0230543629591933 |
GO:0050794 | regulation of cellular process | 0.0242792693903073 |
GO:0030496 | midbody | 0.0242792693903073 |
GO:0016725 | oxidoreductase activity, acting on CH or CH2 groups | 0.0242792693903073 |
GO:0005881 | cytoplasmic microtubule | 0.0242792693903073 |
GO:0030174 | regulation of DNA replication initiation | 0.0242792693903073 |
GO:0009186 | deoxyribonucleoside diphosphate metabolic process | 0.0270695607957624 |
GO:0031575 | G1/S transition checkpoint | 0.0298100699135142 |
GO:0007090 | regulation of S phase of mitotic cell cycle | 0.0325020439979642 |
GO:0005856 | cytoskeleton | 0.0374383002906492 |
GO:0010458 | exit from mitosis | 0.0374383002906492 |
GO:0007096 | regulation of exit from mitosis | 0.0374383002906492 |
GO:0009132 | nucleoside diphosphate metabolic process | 0.0396538422203975 |
GO:0001824 | blastocyst development | 0.0396538422203975 |
GO:0030330 | DNA damage response, signal transduction by p53 class mediator | 0.0449154254061793 |
GO:0043596 | nuclear replication fork | 0.0464162094595863 |
GO:0008156 | negative regulation of DNA replication | 0.0464162094595863 |
GO:0000084 | S phase of mitotic cell cycle | 0.0464162094595863 |
GO:0050789 | regulation of biological process | 0.0464162094595863 |
GO:0017111 | nucleoside-triphosphatase activity | 0.0468039257702775 |
GO:0005876 | spindle microtubule | 0.0478239994334 |
GO:0019104 | DNA N-glycosylase activity | 0.0478239994334 |
GO:0005524 | ATP binding | 0.0493434192289268 |
GO:0051053 | negative regulation of DNA metabolic process | 0.0493434192289268 |
GO:0007051 | spindle organization and biogenesis | 0.0493434192289268 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br><br>disease_data<br>
Ontology term | p-value | n |
---|---|---|
epithelial cell | 1.05e-21 | 253 |
animal cell | 5.56e-17 | 679 |
eukaryotic cell | 5.56e-17 | 679 |
embryonic cell | 8.38e-11 | 250 |
native cell | 1.20e-09 | 722 |
migratory neural crest cell | 8.98e-09 | 41 |
neurectodermal cell | 6.73e-08 | 59 |
neural cell | 1.73e-07 | 25 |
ectodermal cell | 7.36e-07 | 72 |
Ontology term | p-value | n |
---|---|---|
cancer | 8.40e-48 | 235 |
disease of cellular proliferation | 1.42e-46 | 239 |
organ system cancer | 6.42e-24 | 137 |
cell type cancer | 2.61e-23 | 143 |
hematologic cancer | 5.17e-21 | 51 |
immune system cancer | 5.17e-21 | 51 |
carcinoma | 1.35e-18 | 106 |
leukemia | 6.87e-17 | 39 |
myeloid leukemia | 2.44e-12 | 31 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 6.96095 |
MA0004.1 | 0.623722 |
MA0006.1 | 1.67221 |
MA0007.1 | 0.904552 |
MA0009.1 | 0.282049 |
MA0014.1 | 6.33056 |
MA0017.1 | 0.163868 |
MA0019.1 | 0.637656 |
MA0024.1 | 8.18149 |
MA0025.1 | 0.383675 |
MA0027.1 | 1.77546 |
MA0028.1 | 2.71532 |
MA0029.1 | 0.222602 |
MA0030.1 | 0.215031 |
MA0031.1 | 0.174316 |
MA0038.1 | 3.15106 |
MA0040.1 | 0.226506 |
MA0041.1 | 0.0434336 |
MA0042.1 | 0.0344066 |
MA0043.1 | 0.282278 |
MA0046.1 | 0.274202 |
MA0048.1 | 0.0855519 |
MA0050.1 | 0.324596 |
MA0051.1 | 0.0713589 |
MA0052.1 | 0.2291 |
MA0055.1 | 0.0982142 |
MA0056.1 | 0 |
MA0057.1 | 0.210418 |
MA0058.1 | 0.633056 |
MA0059.1 | 0.0757992 |
MA0060.1 | 26.4223 |
MA0061.1 | 0.190797 |
MA0063.1 | 0 |
MA0066.1 | 0.924061 |
MA0067.1 | 0.537012 |
MA0068.1 | 0.110487 |
MA0069.1 | 0.746822 |
MA0070.1 | 1.34024 |
MA0071.1 | 0.212157 |
MA0072.1 | 0.260306 |
MA0073.1 | 3.17614 |
MA0074.1 | 0.248986 |
MA0076.1 | 1.83077 |
MA0077.1 | 0.254892 |
MA0078.1 | 0.371676 |
MA0081.1 | 0.38039 |
MA0083.1 | 0.287504 |
MA0084.1 | 0.703837 |
MA0087.1 | 0.258584 |
MA0088.1 | 1.33508 |
MA0089.1 | 0 |
MA0090.1 | 0.0971665 |
MA0091.1 | 0.350729 |
MA0092.1 | 0.119932 |
MA0093.1 | 1.31245 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 1.98721 |
MA0101.1 | 0.259452 |
MA0103.1 | 0.108723 |
MA0105.1 | 0.655342 |
MA0106.1 | 0.303356 |
MA0107.1 | 0.253705 |
MA0108.2 | 0.172469 |
MA0109.1 | 0 |
MA0111.1 | 0.26112 |
MA0113.1 | 0.0981023 |
MA0114.1 | 0.241927 |
MA0115.1 | 0.471806 |
MA0116.1 | 0.261874 |
MA0117.1 | 0.83365 |
MA0119.1 | 2.04178 |
MA0122.1 | 0.329219 |
MA0124.1 | 0.437263 |
MA0125.1 | 0.36951 |
MA0130.1 | 0 |
MA0131.1 | 0.790153 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.304312 |
MA0136.1 | 0.262713 |
MA0139.1 | 2.28907 |
MA0140.1 | 0.0574137 |
MA0141.1 | 0.192805 |
MA0142.1 | 0.155551 |
MA0143.1 | 0.0981847 |
MA0144.1 | 0.0453363 |
MA0145.1 | 1.29506 |
MA0146.1 | 3.78728 |
MA0147.1 | 1.56199 |
MA0148.1 | 0.0453767 |
MA0149.1 | 1.64974 |
MA0062.2 | 3.64086 |
MA0035.2 | 0.0571647 |
MA0039.2 | 6.75105 |
MA0138.2 | 0.11686 |
MA0002.2 | 0.229858 |
MA0137.2 | 0.0526133 |
MA0104.2 | 1.70965 |
MA0047.2 | 0.0852269 |
MA0112.2 | 0.266225 |
MA0065.2 | 0.1479 |
MA0150.1 | 0.0929679 |
MA0151.1 | 0 |
MA0152.1 | 0.472076 |
MA0153.1 | 0.356306 |
MA0154.1 | 1.23683 |
MA0155.1 | 0.443381 |
MA0156.1 | 0.505588 |
MA0157.1 | 0.140121 |
MA0158.1 | 0 |
MA0159.1 | 0.444017 |
MA0160.1 | 0.187803 |
MA0161.1 | 0 |
MA0162.1 | 2.66971 |
MA0163.1 | 2.33408 |
MA0164.1 | 0.103984 |
MA0080.2 | 0.440272 |
MA0018.2 | 0.632229 |
MA0099.2 | 0.0598901 |
MA0079.2 | 2.9434 |
MA0102.2 | 0.737926 |
MA0258.1 | 0.0396648 |
MA0259.1 | 1.63407 |
MA0442.1 | 0 |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)
TF | #promoters | Enrichment | p-value | q-value |
---|---|---|---|---|
ATF3#467 | 8 | 3.90663904800152 | 0.000880244240459803 | 0.00656327752048128 |
BRCA1#672 | 17 | 7.45938958553922 | 2.82155000628658e-11 | 3.2961953143911e-09 |
CCNT2#905 | 27 | 3.71907483865198 | 4.04350394519681e-11 | 4.60522910068058e-09 |
CEBPB#1051 | 18 | 3.11914472314884 | 4.91862943371598e-06 | 0.000151981283854397 |
CHD2#1106 | 29 | 6.52123178672585 | 1.21757787234564e-18 | 2.81957018647243e-16 |
CTCF#10664 | 17 | 1.9809643117886 | 0.00272554380545113 | 0.0149699221402845 |
E2F1#1869 | 43 | 4.5873420921698 | 1.50454397185039e-26 | 5.13506757764978e-24 |
E2F4#1874 | 46 | 12.6680603152844 | 1.76573713046307e-51 | 1.33631753745241e-48 |
E2F6#1876 | 40 | 4.36274411451947 | 2.41674140627385e-22 | 6.84016411191962e-20 |
EGR1#1958 | 26 | 2.81940557532747 | 5.55188025335704e-08 | 3.48247941009223e-06 |
ELF1#1997 | 37 | 3.42499183643215 | 5.53203736297706e-16 | 1.06597869031727e-13 |
ELK4#2005 | 17 | 6.00014322160775 | 8.10042517794397e-10 | 7.62849689052561e-08 |
ETS1#2113 | 25 | 5.28737006641431 | 1.54067483751828e-13 | 2.36279793473674e-11 |
FOS#2353 | 24 | 4.6945853785536 | 8.28022629338877e-12 | 1.04315868981331e-09 |
GABPB1#2553 | 29 | 4.4557137228105 | 3.3500796044433e-14 | 5.54483302390577e-12 |
GTF2B#2959 | 6 | 4.16658651317273 | 0.00300489290373989 | 0.0159684531610284 |
GTF2F1#2962 | 19 | 5.2620338403999 | 5.13746641815713e-10 | 4.95888960486056e-08 |
HDAC2#3066 | 11 | 3.2080831000628 | 0.000452479360997979 | 0.00420730875919409 |
HEY1#23462 | 46 | 4.04011104310571 | 1.25461817719195e-28 | 4.69645404328853e-26 |
HMGN3#9324 | 30 | 5.33383547175039 | 5.44060644509474e-17 | 1.10978807913916e-14 |
IRF1#3659 | 40 | 6.64101195962078 | 1.93474408407452e-29 | 7.5678927863917e-27 |
IRF3#3661 | 16 | 16.3415485953007 | 9.3341582565583e-16 | 1.76283933843887e-13 |
MAX#4149 | 31 | 4.34846132128741 | 3.50041690683563e-15 | 6.24923147577788e-13 |
MXI1#4601 | 28 | 6.06356533924479 | 4.94337318434796e-17 | 1.01430442436172e-14 |
MYC#4609 | 36 | 4.08700320386823 | 7.36533682248907e-18 | 1.60590482756563e-15 |
NANOG#79923 | 7 | 4.4502923775454 | 0.000903667668463766 | 0.0065819197731144 |
NFKB1#4790 | 29 | 3.45986607177437 | 2.34035757418545e-11 | 2.79023521336021e-09 |
NFYA#4800 | 25 | 10.0139025542557 | 5.08776226885587e-20 | 1.2928486705524e-17 |
NFYB#4801 | 27 | 9.8372699531627 | 1.15547122494712e-21 | 3.1508161687272e-19 |
NR2C2#7182 | 5 | 3.54506640274357 | 0.0130650635206556 | 0.0463470048243522 |
NRF1#4899 | 17 | 4.51249457850186 | 5.70518661524608e-08 | 3.57006581731387e-06 |
PAX5#5079 | 19 | 2.75482054548649 | 1.47724405940275e-05 | 0.000350401754076684 |
PBX3#5090 | 10 | 4.76402449711829 | 3.49622827593698e-05 | 0.00068149045336055 |
POLR2A#5430 | 46 | 2.14745317655807 | 5.35449299434509e-16 | 1.03367448028911e-13 |
POU2F2#5452 | 16 | 3.16734749834523 | 1.71364315144799e-05 | 0.00039205077129042 |
REST#5978 | 18 | 3.77609819326749 | 2.99108731249004e-07 | 1.50911192187994e-05 |
RFX5#5993 | 26 | 6.80968872841462 | 8.224990812016e-17 | 1.66474770429484e-14 |
RXRA#6256 | 7 | 3.05483304291158 | 0.00735215887669258 | 0.030396742841649 |
SETDB1#9869 | 7 | 6.13565615752333 | 0.000131675988918595 | 0.00173113149630779 |
SIN3A#25942 | 46 | 5.40888472681514 | 1.84636119222069e-34 | 8.84550993368518e-32 |
SIX5#147912 | 15 | 5.57175500721489 | 2.87913874308864e-08 | 1.96019798689331e-06 |
SMARCB1#6598 | 11 | 4.36477986071156 | 2.96036183323798e-05 | 0.000613690411872849 |
SP1#6667 | 44 | 5.45062566604782 | 3.87370492437202e-31 | 1.61826347438596e-28 |
SP2#6668 | 17 | 9.6654351825078 | 4.73722805592909e-13 | 6.91959945361088e-11 |
SREBF1#6720 | 5 | 5.10933146092264 | 0.0028870285591593 | 0.0156186674794114 |
SRF#6722 | 9 | 2.69944792085892 | 0.00519538732246168 | 0.0240770791875477 |
TAF1#6872 | 46 | 3.34304628574529 | 7.65155694296417e-25 | 2.42157865323102e-22 |
TAF7#6879 | 25 | 6.21362467658908 | 3.81299227824374e-15 | 6.7840732631601e-13 |
TBP#6908 | 45 | 3.62618871563777 | 8.29246962520681e-25 | 2.60860613008125e-22 |
TCF7L2#6934 | 11 | 2.5754770042285 | 0.00272884398475863 | 0.0149856839270274 |
TFAP2C#7022 | 18 | 4.22969815168444 | 5.35084286782104e-08 | 3.39511955207996e-06 |
THAP1#55145 | 9 | 6.13744133534048 | 1.27803550244023e-05 | 0.000313472874211731 |
TRIM28#10155 | 10 | 4.04141848810055 | 0.000137674221539987 | 0.00179911887179863 |
USF1#7391 | 21 | 2.90416271350798 | 1.61975465913921e-06 | 6.1447714074043e-05 |
USF2#7392 | 10 | 2.82439073588469 | 0.00225552973162 | 0.0128108151860268 |
YY1#7528 | 31 | 3.30970202707542 | 7.08853204881519e-12 | 9.0063162852337e-10 |
ZBTB33#10009 | 6 | 4.13018152564972 | 0.00313755291829468 | 0.0164747556175856 |
ZBTB7A#51341 | 24 | 3.83577876932655 | 5.85386447540758e-10 | 5.62439514210757e-08 |
ZEB1#6935 | 8 | 2.93711861174676 | 0.0052013448361008 | 0.0241036186421233 |
ZNF143#7702 | 15 | 4.40245974529171 | 6.12780371364921e-07 | 2.81063545037246e-05 |
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data