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{{UBERON
{{UBERON
|id=UBERON:0001777
|alt_id=UBERON:FMA_58306-MA_0001245
|name=substantia propria of cornea
|namespace=
|def="The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent. It is composed of about 200 flattened lamell��スヲ (plates of collagen fibrils), superimposed one on another. They are each about 1.5-2.5 micrometres in thickness. These fibrils run at different angles between the limbi. Fibres of the layers frequently interweave, the anterior lamell��スヲ interweaving more than posterior lamell��スヲ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamell��スヲ. The lamell��スヲ are produced by keratocytes (corneal corpuscles), which occupy about 10% of the substantia propria. These lamell��スヲ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the sclera. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients. [WP,unvetted]." [Wikipedia:Corneal_stroma]
|xref=EFO:0002514;;EMAPA:17602;;FMA:58306;;GAID:893;;http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Gray871.png/200px-Gray871.png;;MA:0001245;;MESH:A.09.371.060.217.228;;ncithesaurus:Corneal_Stroma;;SCTID:362511000;;TAO:0002189;;ZFA:0001685
|is_a=UBERON:0003566;;UBERON:0003891;;UBERON:0010313
|synonym="cornea stroma" EXACT [];;"corneal stroma" EXACT [];;"stroma of cornea" EXACT [];;"substantia propria" RELATED []
|comment=This class was created automatically from a combination of ontologies
|comment=This class was created automatically from a combination of ontologies
|alt_id=UBERON:FMA_58306-MA_0001245
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent. It is composed of about 200 flattened lamell��スヲ (plates of collagen fibrils), superimposed one on another. They are each about 1.5-2.5 micrometres in thickness. These fibrils run at different angles between the limbi. Fibres of the layers frequently interweave, the anterior lamell��スヲ interweaving more than posterior lamell��スヲ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamell��スヲ. The lamell��スヲ are produced by keratocytes (corneal corpuscles), which occupy about 10% of the substantia propria. These lamell��スヲ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the sclera. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients. [WP,unvetted]." [Wikipedia:Corneal_stroma]
|subset=uberon_slim;;vertebrate_core
|derives_from=
|derives_from=
|develops_from=UBERON:0002342
|develops_from=UBERON:0007213
|disjoint_from=
|has_quality=
|has_quality=
|id=UBERON:0001777
|is_a=UBERON:0003891 ;;UBERON:0010313
|is_obsolete=
|located_in=
|located_in=
|name=substantia propria of cornea
|namespace=
|obo_creation_date=
|part_of=UBERON:0000964
|part_of=UBERON:0000964
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "Portion of tissue that is located basal to Bowman's layer and distal to Descemet's membrane and is comprised largely of connective tissue.[TAO]" xsd:string
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "Portion of tissue that is located basal to Bowman's layer and distal to Descemet's membrane and is comprised largely of connective tissue.[TAO]" xsd:string
|is_obsolete=
|subset=uberon_slim;;vertebrate_core
|preceded_by=
|synonym="cornea stroma" EXACT [];;"corneal stroma" EXACT [];;"stroma of cornea" EXACT [];;"substantia propria" RELATED []
|union_of=
|xref=EFO:0002514;;EMAPA:17602;;FMA:58306;;GAID:893;;http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Gray871.png/200px-Gray871.png;;MA:0001245;;MESH:A.09.371.060.217.228;;ncithesaurus:Corneal_Stroma;;SCTID:362511000;;TAO:0002189;;ZFA:0001685
}}
}}

Revision as of 11:05, 12 September 2014

Name:substantia propria of cornea
Definition:"The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent. It is composed of about 200 flattened lamell��スヲ (plates of collagen fibrils), superimposed one on another. They are each about 1.5-2.5 micrometres in thickness. These fibrils run at different angles between the limbi. Fibres of the layers frequently interweave, the anterior lamell��スヲ interweaving more than posterior lamell��スヲ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamell��スヲ. The lamell��スヲ are produced by keratocytes (corneal corpuscles), which occupy about 10% of the substantia propria. These lamell��スヲ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the sclera. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients. [WP,unvetted]." [Wikipedia:Corneal_stroma]
Xrefs:
links:

EFO:0002514
EMAPA:17602
FMA:58306
GAID:893
[ 200px-Gray871.png 200px-Gray871.png]
MA:0001245
MESH:A.09.371.060.217.228
ncithesaurus:Corneal_Stroma
SCTID:362511000
TAO:0002189

ZFA:0001685
Synonyms: "cornea stroma" EXACT []
"corneal stroma" EXACT []
"stroma of cornea" EXACT []
"substantia propria" RELATED []
Comments:This class was created automatically from a combination of ontologies
Alt_id: UBERON:FMA_58306-MA_0001245
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0003891(stroma),UBERON:0010313(neural crest-derived structure)
develops_from:UBERON:0007213(mesenchyme derived from head neural crest)
part_of:UBERON:0000964(cornea)



Children

part of:CL:0002363 (keratocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001777 (substantia propria of cornea), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
1.55e-98FFCP PHASE1:Hg19::chr7:150910973..150910976,-#_30f7b30922b07b3050d9176a9b5d85eap@chr7:150910973..150910976, -
1.55e-98FFCP PHASE2:Hg19::chr3:52362029..52362031,+#_30f7b30922b07b3050d9176a9b5d85eap@chr3:52362029..52362031, +
1.55e-98FFCP PHASE1:Hg19::chr3:52362029..52362031,+#_30f7b30922b07b3050d9176a9b5d85eap@chr3:52362029..52362031, +
1.55e-98FFCP PHASE2:Hg19::chr7:150910973..150910976,-#_30f7b30922b07b3050d9176a9b5d85eap@chr7:150910973..150910976, -
4.52e-50FFCP PHASE1:Hg19::chr6:113369869..113369877,+#_1bbd5c58093665e40218473c455f369dp@chr6:113369869..113369877, +
4.52e-50FFCP PHASE1:Hg19::chr10:92617531..92617541,-#_1bbd5c58093665e40218473c455f369dp8@HTR7
4.52e-50FFCP PHASE2:Hg19::chr15:49255230..49255248,-#_1bbd5c58093665e40218473c455f369dp16@SHC4
4.52e-50FFCP PHASE2:Hg19::chr8:22932230..22932233,-#_1bbd5c58093665e40218473c455f369dp5@ENST00000520840, p5@ENST00000523806
4.52e-50FFCP PHASE1:Hg19::chr8:22932230..22932233,-#_1bbd5c58093665e40218473c455f369dp5@ENST00000520840, p5@ENST00000523806
4.52e-50FFCP PHASE1:Hg19::chr15:49255230..49255248,-#_1bbd5c58093665e40218473c455f369dp16@SHC4
4.52e-50FFCP PHASE2:Hg19::chr6:113369869..113369877,+#_1bbd5c58093665e40218473c455f369dp@chr6:113369869..113369877, +
4.52e-50FFCP PHASE2:Hg19::chr10:92617531..92617541,-#_1bbd5c58093665e40218473c455f369dp8@HTR7
5.04e-34FFCP PHASE2:Hg19::chr21:47410794..47410799,+#_aba62d1b9ef569dcb04ef444be94a928p@chr21:47410794..47410799, +
5.04e-34FFCP PHASE1:Hg19::chr21:47410794..47410799,+#_aba62d1b9ef569dcb04ef444be94a928p@chr21:47410794..47410799, +
5.04e-34FFCP PHASE2:Hg19::chr1:44820685..44820695,-#_aba62d1b9ef569dcb04ef444be94a928p10@ERI3
5.04e-34FFCP PHASE1:Hg19::chr1:44820685..44820695,-#_aba62d1b9ef569dcb04ef444be94a928p10@ERI3
5.04e-34FFCP PHASE2:Hg19::chr6:151770193..151770196,-#_aba62d1b9ef569dcb04ef444be94a928p@chr6:151770193..151770196, -
5.04e-34FFCP PHASE1:Hg19::chr6:151770193..151770196,-#_aba62d1b9ef569dcb04ef444be94a928p@chr6:151770193..151770196, -
7.05e-34FFCP PHASE1:Hg19::chr5:79375654..79375674,+#_b5550821167fa927230b8bf46d90a4a9p@chr5:79375654..79375674, +
7.05e-34FFCP PHASE2:Hg19::chr15:101459410..101459421,-#_b5550821167fa927230b8bf46d90a4a9p2@ENST00000560068
7.05e-34FFCP PHASE2:Hg19::chr11:65265332..65265342,+#_b5550821167fa927230b8bf46d90a4a9p19@MALAT1
7.05e-34FFCP PHASE1:Hg19::chr11:65265332..65265342,+#_b5550821167fa927230b8bf46d90a4a9p19@MALAT1
7.05e-34FFCP PHASE2:Hg19::chr2:25383828..25383855,-#_b5550821167fa927230b8bf46d90a4a9p4@POMC
7.05e-34FFCP PHASE2:Hg19::chr1:9970194..9970195,-#_b5550821167fa927230b8bf46d90a4a9p14@CTNNBIP1
7.05e-34FFCP PHASE2:Hg19::chr10:43133595..43133606,-#_b5550821167fa927230b8bf46d90a4a9p@chr10:43133595..43133606, -
7.05e-34FFCP PHASE1:Hg19::chr15:101459410..101459421,-#_b5550821167fa927230b8bf46d90a4a9p2@ENST00000560068
7.05e-34FFCP PHASE1:Hg19::chr2:25383828..25383855,-#_b5550821167fa927230b8bf46d90a4a9p4@POMC
7.05e-34FFCP PHASE2:Hg19::chr10:74020629..74020634,-#_b5550821167fa927230b8bf46d90a4a9p@chr10:74020629..74020634, -
7.05e-34FFCP PHASE1:Hg19::chr1:9970194..9970195,-#_b5550821167fa927230b8bf46d90a4a9p14@CTNNBIP1
7.05e-34FFCP PHASE1:Hg19::chr10:43133595..43133606,-#_b5550821167fa927230b8bf46d90a4a9p@chr10:43133595..43133606, -
7.05e-34FFCP PHASE1:Hg19::chr10:74020629..74020634,-#_b5550821167fa927230b8bf46d90a4a9p@chr10:74020629..74020634, -
7.05e-34FFCP PHASE2:Hg19::chr5:79375654..79375674,+#_b5550821167fa927230b8bf46d90a4a9p@chr5:79375654..79375674, +
6.41e-31FFCP PHASE2:Hg19::chr4:111536534..111536575,-#_8b16d2da7d04c381833ab6d4a3d4191fp1@ENST00000503456
6.41e-31FFCP PHASE1:Hg19::chr4:111536534..111536575,-#_8b16d2da7d04c381833ab6d4a3d4191fp1@ENST00000503456
4.55e-29FFCP PHASE2:Hg19::chrX:19688475..19688492,-#_72b8f44f4f9c9883b82a3be157be9b49p26@SH3KBP1
4.55e-29FFCP PHASE1:Hg19::chrX:19688475..19688492,-#_72b8f44f4f9c9883b82a3be157be9b49p26@SH3KBP1
9.18e-26FFCP PHASE1:Hg19::chr1:93646042..93646043,-#_53de05d9a3c9c8f56c37ffadd63fef2cp7@TMED5
9.18e-26FFCP PHASE2:Hg19::chr7:6049190..6049209,+#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr7:6049190..6049209, +
9.18e-26FFCP PHASE1:Hg19::chr10:86153606..86153623,+#_53de05d9a3c9c8f56c37ffadd63fef2cp9@FAM190B
9.18e-26FFCP PHASE2:Hg19::chr4:120546882..120546885,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr4:120546882..120546885, -
9.18e-26FFCP PHASE2:Hg19::chr1:179335101..179335112,+#_53de05d9a3c9c8f56c37ffadd63fef2cp6@AXDND1
9.18e-26FFCP PHASE1:Hg19::chr4:73434498..73434509,-#_53de05d9a3c9c8f56c37ffadd63fef2cp6@ADAMTS3
9.18e-26FFCP PHASE1:Hg19::chr20:60758060..60758074,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr20:60758060..60758074, -
9.18e-26FFCP PHASE2:Hg19::chr3:9956047..9956079,+#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr3:9956047..9956079, +
9.18e-26FFCP PHASE1:Hg19::chr11:34073641..34073656,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr11:34073641..34073656, -
9.18e-26FFCP PHASE1:Hg19::chr17:30185971..30185986,-#_53de05d9a3c9c8f56c37ffadd63fef2cp7@C17orf79
9.18e-26FFCP PHASE2:Hg19::chr1:36024782..36024791,+#_53de05d9a3c9c8f56c37ffadd63fef2cp4@AB383919
9.18e-26FFCP PHASE1:Hg19::chr7:6049190..6049209,+#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr7:6049190..6049209, +
9.18e-26FFCP PHASE1:Hg19::chr4:120546882..120546885,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr4:120546882..120546885, -
9.18e-26FFCP PHASE1:Hg19::chr3:9956047..9956079,+#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr3:9956047..9956079, +
9.18e-26FFCP PHASE1:Hg19::chr1:179335101..179335112,+#_53de05d9a3c9c8f56c37ffadd63fef2cp6@AXDND1
9.18e-26FFCP PHASE1:Hg19::chr1:151171326..151171337,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr1:151171326..151171337, -
9.18e-26FFCP PHASE1:Hg19::chr1:36024782..36024791,+#_53de05d9a3c9c8f56c37ffadd63fef2cp4@AB383919
9.18e-26FFCP PHASE2:Hg19::chr21:47681190..47681194,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr21:47681190..47681194, -
9.18e-26FFCP PHASE2:Hg19::chr16:10590513..10590515,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr16:10590513..10590515, -
9.18e-26FFCP PHASE2:Hg19::chr4:57522753..57522760,-#_53de05d9a3c9c8f56c37ffadd63fef2cp18@HOPX
9.18e-26FFCP PHASE1:Hg19::chr21:47681190..47681194,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr21:47681190..47681194, -
9.18e-26FFCP PHASE2:Hg19::chr15:90344775..90344794,+#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr15:90344775..90344794, +
9.18e-26FFCP PHASE2:Hg19::chr7:100806199..100806216,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr7:100806199..100806216, -
9.18e-26FFCP PHASE2:Hg19::chr2:219540880..219540912,+#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr2:219540880..219540912, +
9.18e-26FFCP PHASE1:Hg19::chr16:10590513..10590515,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr16:10590513..10590515, -
9.18e-26FFCP PHASE1:Hg19::chr7:100806199..100806216,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr7:100806199..100806216, -
9.18e-26FFCP PHASE2:Hg19::chr21:47397571..47397582,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr21:47397571..47397582, -
9.18e-26FFCP PHASE1:Hg19::chr4:57522753..57522760,-#_53de05d9a3c9c8f56c37ffadd63fef2cp18@HOPX
9.18e-26FFCP PHASE1:Hg19::chr15:90344775..90344794,+#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr15:90344775..90344794, +
9.18e-26FFCP PHASE1:Hg19::chr2:219540880..219540912,+#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr2:219540880..219540912, +
9.18e-26FFCP PHASE1:Hg19::chr21:47397571..47397582,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr21:47397571..47397582, -
9.18e-26FFCP PHASE2:Hg19::chr4:73434498..73434509,-#_53de05d9a3c9c8f56c37ffadd63fef2cp6@ADAMTS3
9.18e-26FFCP PHASE2:Hg19::chr17:30185971..30185986,-#_53de05d9a3c9c8f56c37ffadd63fef2cp7@C17orf79
9.18e-26FFCP PHASE2:Hg19::chr12:53693440..53693450,-#_53de05d9a3c9c8f56c37ffadd63fef2cp2@CU687581
9.18e-26FFCP PHASE2:Hg19::chr10:86153606..86153623,+#_53de05d9a3c9c8f56c37ffadd63fef2cp9@FAM190B
9.18e-26FFCP PHASE1:Hg19::chr12:53693440..53693450,-#_53de05d9a3c9c8f56c37ffadd63fef2cp2@CU687581
9.18e-26FFCP PHASE2:Hg19::chr1:93646042..93646043,-#_53de05d9a3c9c8f56c37ffadd63fef2cp7@TMED5
9.18e-26FFCP PHASE2:Hg19::chr11:34073641..34073656,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr11:34073641..34073656, -
9.18e-26FFCP PHASE2:Hg19::chr1:151171326..151171337,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr1:151171326..151171337, -
9.18e-26FFCP PHASE2:Hg19::chr20:60758060..60758074,-#_53de05d9a3c9c8f56c37ffadd63fef2cp@chr20:60758060..60758074, -
6.02e-24FFCP PHASE1:Hg19::chr1:145589059..145589070,-#_449cd59297011b978ac9c00cb5d621f6p3@NUDT17
6.02e-24FFCP PHASE2:Hg19::chr1:145589059..145589070,-#_449cd59297011b978ac9c00cb5d621f6p3@NUDT17
3.81e-21FFCP PHASE1:Hg19::chr17:19648416..19648426,-#_c643b3bbedb7ca9a2b69caa0557e7e3ep13@ALDH3A1
3.81e-21FFCP PHASE2:Hg19::chr17:19648416..19648426,-#_c643b3bbedb7ca9a2b69caa0557e7e3ep13@ALDH3A1
4.66e-21FFCP PHASE1:Hg19::chr6:41562324..41562340,+#_a132959ce27ce8b4e0be0ff5504fbf07p16@FOXP4
4.66e-21FFCP PHASE2:Hg19::chr4:52917466..52917498,-#_a132959ce27ce8b4e0be0ff5504fbf07p@chr4:52917466..52917498, -
4.66e-21FFCP PHASE1:Hg19::chr4:52917466..52917498,-#_a132959ce27ce8b4e0be0ff5504fbf07p@chr4:52917466..52917498, -
4.66e-21FFCP PHASE2:Hg19::chr6:41562324..41562340,+#_a132959ce27ce8b4e0be0ff5504fbf07p16@FOXP4
5.7e-21FFCP PHASE1:Hg19::chr5:142254452..142254462,+#_6827444bb6735ba3e4bf22b13bf4646bp29@ARHGAP26
5.7e-21FFCP PHASE2:Hg19::chr7:73118172..73118185,-#_6827444bb6735ba3e4bf22b13bf4646bp3@STX1A
5.7e-21FFCP PHASE1:Hg19::chr7:73118172..73118185,-#_6827444bb6735ba3e4bf22b13bf4646bp3@STX1A
5.7e-21FFCP PHASE2:Hg19::chr8:27686258..27686262,-#_6827444bb6735ba3e4bf22b13bf4646bp@chr8:27686258..27686262, -
5.7e-21FFCP PHASE1:Hg19::chr8:27686258..27686262,-#_6827444bb6735ba3e4bf22b13bf4646bp@chr8:27686258..27686262, -
5.7e-21FFCP PHASE2:Hg19::chr19:48244695..48244702,+#_6827444bb6735ba3e4bf22b13bf4646bp14@EHD2
5.7e-21FFCP PHASE2:Hg19::chr12:58141331..58141342,+#_6827444bb6735ba3e4bf22b13bf4646bp@chr12:58141331..58141342, +
5.7e-21FFCP PHASE1:Hg19::chr19:48244695..48244702,+#_6827444bb6735ba3e4bf22b13bf4646bp14@EHD2
5.7e-21FFCP PHASE1:Hg19::chr12:58141331..58141342,+#_6827444bb6735ba3e4bf22b13bf4646bp@chr12:58141331..58141342, +
5.7e-21FFCP PHASE2:Hg19::chr5:142254452..142254462,+#_6827444bb6735ba3e4bf22b13bf4646bp29@ARHGAP26
6.96e-21FFCP PHASE1:Hg19::chr5:6766044..6766055,+#_3b19ef7bdbfd9a808b1be5d581addf21p2@ENST00000506093
6.96e-21FFCP PHASE1:Hg19::chr2:37898966..37898999,+#_3b19ef7bdbfd9a808b1be5d581addf21p@chr2:37898966..37898999, +
6.96e-21FFCP PHASE1:Hg19::chr15:90348577..90348582,-#_3b19ef7bdbfd9a808b1be5d581addf21p34@ANPEP
6.96e-21FFCP PHASE1:Hg19::chr17:45144823..45144834,-#_3b19ef7bdbfd9a808b1be5d581addf21p@chr17:45144823..45144834, -
6.96e-21FFCP PHASE2:Hg19::chr6:30585100..30585105,-#_3b19ef7bdbfd9a808b1be5d581addf21p19@PPP1R10
6.96e-21FFCP PHASE2:Hg19::chr17:71283257..71283270,-#_3b19ef7bdbfd9a808b1be5d581addf21p@chr17:71283257..71283270, -










Property "Property value" (as page type) with input value "UBPROP:0000001 "Portion of tissue that is located basal to Bowman's layer and distal to Descemet's membrane and is comprised largely of connective tissue.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.