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Coexpression cluster:C477

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Full id: C477_Mesenchymal_Amniotic_Placental_chorionic_umbilical_Cardiac_acute



Phase1 CAGE Peaks

Hg19::chr11:1480395..1480413,+p@chr11:1480395..1480413
+
Hg19::chr11:1897722..1897737,+p18@LSP1
Hg19::chr12:123465379..123465397,+p7@ARL6IP4
Hg19::chr14:52781196..52781213,+p3@PTGER2
Hg19::chr16:49698228..49698243,-p2@ZNF423
Hg19::chr16:89686991..89687015,+p5@DPEP1
Hg19::chr16:89687026..89687041,+p7@DPEP1
Hg19::chr17:37824505..37824516,+p11@PNMT
Hg19::chr17:37824531..37824553,+p6@PNMT
Hg19::chr17:37824598..37824605,+p15@PNMT
Hg19::chr17:37824700..37824714,+p2@PNMT
Hg19::chr17:37825180..37825196,+p@chr17:37825180..37825196
+
Hg19::chr17:7836505..7836526,+p3@CNTROB
Hg19::chr18:71928422..71928428,-p3@CYB5A
Hg19::chr1:1567682..1567692,+p1@MMP23A
Hg19::chr3:154801312..154801336,+p29@MME
Hg19::chr3:162256416..162256425,-p@chr3:162256416..162256425
-
Hg19::chr4:1166954..1166973,-p13@SPON2
Hg19::chr7:101556503..101556516,+p12@CUX1
Hg19::chr7:95979117..95979120,+p@chr7:95979117..95979120
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0004603phenylethanolamine N-methyltransferase activity0.0459019238428391
GO:0007099centriole replication0.0459019238428391
GO:0051299centrosome separation0.0459019238428391
GO:0005792microsome0.0459019238428391
GO:0042598vesicular fraction0.0459019238428391
GO:0004237membrane dipeptidase activity0.0459019238428391
GO:0016564transcription repressor activity0.0466288745382801
GO:0005814centriole0.0466288745382801
GO:0051298centrosome duplication0.0466288745382801
GO:0004960thromboxane receptor activity0.0466288745382801
GO:0042423catecholamine biosynthetic process0.0466288745382801
GO:0016481negative regulation of transcription0.0466288745382801
GO:0016805dipeptidase activity0.0466288745382801
GO:0042491auditory receptor cell differentiation0.0466288745382801
GO:0045934negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0466288745382801
GO:0007098centrosome cycle0.0466288745382801
GO:0004245neprilysin activity0.0466288745382801
GO:0042490mechanoreceptor differentiation0.0466288745382801
GO:0060113inner ear receptor cell differentiation0.0466288745382801
GO:0004957prostaglandin E receptor activity0.0466288745382801
GO:0008237metallopeptidase activity0.0466288745382801
GO:0051297centrosome organization and biogenesis0.0466288745382801
GO:0031023microtubule organizing center organization and biogenesis0.0466288745382801
GO:0031324negative regulation of cellular metabolic process0.0466288745382801
GO:0006928cell motility0.0466288745382801
GO:0051674localization of cell0.0466288745382801
GO:0008239dipeptidyl-peptidase activity0.0466288745382801
GO:0016806dipeptidyl-peptidase and tripeptidyl-peptidase activity0.0466288745382801



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
mesenchyme of umbilical cord1.61e-096


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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