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UBERON:0004755

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Name:skeletal tissue
Definition:"Connective tissue that functions in mechanical and structural support." [VSAO:0000015]
Xrefs:
links:

SCTID:309311006
VSAO:0000015
XAO:0004038

ZFA:0005619
Synonyms: "mineralized tissue" NARROW []
Comments:Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0002384(connective tissue)
part_of:UBERON:0004765(skeletal element)



Children

is a:UBERON:0002418 (cartilage tissue),UBERON:0002481 (bone tissue)
disjoint from:UBERON:0003714 (neural tissue)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0004755 (skeletal tissue), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.71e-66FFCP PHASE1:Hg19::chr1:78769549..78769554,+#_59826314079ec5dfd333c5f6c965f16cp5@PTGFR
1.71e-66FFCP PHASE2:Hg19::chr1:78769549..78769554,+#_59826314079ec5dfd333c5f6c965f16cp5@PTGFR
2.39e-66FFCP PHASE2:Hg19::chr2:175614951..175614956,-#_7052249764c66f22cd325eeb139b417ep@chr2:175614951..175614956, -
2.39e-66FFCP PHASE2:Hg19::chr1:198595872..198595878,+#_7052249764c66f22cd325eeb139b417ep@chr1:198595872..198595878, +
2.39e-66FFCP PHASE2:Hg19::chr19:56047669..56047674,-#_7052249764c66f22cd325eeb139b417ep7@SBK2
2.39e-66FFCP PHASE1:Hg19::chr8:107074411..107074421,+#_7052249764c66f22cd325eeb139b417ep@chr8:107074411..107074421, +
2.39e-66FFCP PHASE1:Hg19::chr3:1577586..1577600,-#_7052249764c66f22cd325eeb139b417ep@chr3:1577586..1577600, -
2.39e-66FFCP PHASE1:Hg19::chr2:175629357..175629367,-#_7052249764c66f22cd325eeb139b417ep6@CHRNA1
2.39e-66FFCP PHASE1:Hg19::chr12:70351971..70351975,+#_7052249764c66f22cd325eeb139b417ep@chr12:70351971..70351975, +
2.39e-66FFCP PHASE2:Hg19::chr7:18439523..18439524,+#_7052249764c66f22cd325eeb139b417ep@chr7:18439523..18439524, +
2.39e-66FFCP PHASE1:Hg19::chr3:2141851..2141858,-#_7052249764c66f22cd325eeb139b417ep@chr3:2141851..2141858, -
2.39e-66FFCP PHASE1:Hg19::chr3:99680705..99680734,+#_7052249764c66f22cd325eeb139b417ep@chr3:99680705..99680734, +
2.39e-66FFCP PHASE2:Hg19::chr15:95751475..95751482,+#_7052249764c66f22cd325eeb139b417ep@chr15:95751475..95751482, +
2.39e-66FFCP PHASE2:Hg19::chr6:96913362..96913393,-#_7052249764c66f22cd325eeb139b417ep@chr6:96913362..96913393, -
2.39e-66FFCP PHASE2:Hg19::chr13:23733790..23733815,-#_7052249764c66f22cd325eeb139b417ep@chr13:23733790..23733815, -
2.39e-66FFCP PHASE2:Hg19::chr1:154942206..154942211,-#_7052249764c66f22cd325eeb139b417ep@chr1:154942206..154942211, -
2.39e-66FFCP PHASE1:Hg19::chr2:53436150..53436154,-#_7052249764c66f22cd325eeb139b417ep@chr2:53436150..53436154, -
2.39e-66FFCP PHASE1:Hg19::chr20:36848135..36848142,-#_7052249764c66f22cd325eeb139b417ep@chr20:36848135..36848142, -
2.39e-66FFCP PHASE2:Hg19::chr6:150735319..150735330,+#_7052249764c66f22cd325eeb139b417ep@chr6:150735319..150735330, +
2.39e-66FFCP PHASE2:Hg19::chr3:1577559..1577577,-#_7052249764c66f22cd325eeb139b417ep@chr3:1577559..1577577, -
2.39e-66FFCP PHASE1:Hg19::chr13:23368370..23368374,+#_7052249764c66f22cd325eeb139b417ep@chr13:23368370..23368374, +
2.39e-66FFCP PHASE2:Hg19::chr18:74535969..74535980,-#_7052249764c66f22cd325eeb139b417ep@chr18:74535969..74535980, -
2.39e-66FFCP PHASE1:Hg19::chr6:152589291..152589303,-#_7052249764c66f22cd325eeb139b417ep38@SYNE1
2.39e-66FFCP PHASE2:Hg19::chr1:145473297..145473306,+#_7052249764c66f22cd325eeb139b417ep7@AB464458
2.39e-66FFCP PHASE1:Hg19::chr2:206927652..206927658,-#_7052249764c66f22cd325eeb139b417ep@chr2:206927652..206927658, -
2.39e-66FFCP PHASE2:Hg19::chr2:74780643..74780673,-#_7052249764c66f22cd325eeb139b417ep30@LOXL3
2.39e-66FFCP PHASE2:Hg19::chr21:38309134..38309135,-#_7052249764c66f22cd325eeb139b417ep@chr21:38309134..38309135, -
2.39e-66FFCP PHASE2:Hg19::chr1:192444852..192444861,+#_7052249764c66f22cd325eeb139b417ep@chr1:192444852..192444861, +
2.39e-66FFCP PHASE2:Hg19::chr6:152590257..152590288,-#_7052249764c66f22cd325eeb139b417ep@chr6:152590257..152590288, -
2.39e-66FFCP PHASE2:Hg19::chr1:228806586..228806591,+#_7052249764c66f22cd325eeb139b417ep@chr1:228806586..228806591, +
2.39e-66FFCP PHASE2:Hg19::chr11:30105969..30105977,-#_7052249764c66f22cd325eeb139b417ep1@ENST00000527819
2.39e-66FFCP PHASE1:Hg19::chr4:139817600..139817609,-#_7052249764c66f22cd325eeb139b417ep@chr4:139817600..139817609, -
2.39e-66FFCP PHASE1:Hg19::chr2:188420470..188420480,+#_7052249764c66f22cd325eeb139b417ep@chr2:188420470..188420480, +
2.39e-66FFCP PHASE2:Hg19::chr12:80818259..80818266,+#_7052249764c66f22cd325eeb139b417ep@chr12:80818259..80818266, +
2.39e-66FFCP PHASE2:Hg19::chr3:2141949..2141956,+#_7052249764c66f22cd325eeb139b417ep21@CNTN4
2.39e-66FFCP PHASE1:Hg19::chr1:112916133..112916138,-#_7052249764c66f22cd325eeb139b417ep@chr1:112916133..112916138, -
2.39e-66FFCP PHASE1:Hg19::chr3:2141993..2142006,+#_7052249764c66f22cd325eeb139b417ep6@CNTN4
2.39e-66FFCP PHASE1:Hg19::chr9:12848028..12848033,-#_7052249764c66f22cd325eeb139b417ep@chr9:12848028..12848033, -
2.39e-66FFCP PHASE2:Hg19::chr12:89917192..89917200,-#_7052249764c66f22cd325eeb139b417ep@chr12:89917192..89917200, -
2.39e-66FFCP PHASE1:Hg19::chr6:109702786..109702795,-#_7052249764c66f22cd325eeb139b417ep21@CD164
2.39e-66FFCP PHASE1:Hg19::chr1:192407901..192407907,-#_7052249764c66f22cd325eeb139b417ep@chr1:192407901..192407907, -
2.39e-66FFCP PHASE1:Hg19::chr9:79634044..79634053,-#_7052249764c66f22cd325eeb139b417ep@chr9:79634044..79634053, -
2.39e-66FFCP PHASE2:Hg19::chr2:27806224..27806236,+#_7052249764c66f22cd325eeb139b417ep5@ZNF512
2.39e-66FFCP PHASE1:Hg19::chr4:72885984..72885997,-#_7052249764c66f22cd325eeb139b417ep@chr4:72885984..72885997, -
2.39e-66FFCP PHASE1:Hg19::chr1:43637641..43637648,-#_7052249764c66f22cd325eeb139b417ep16@EBNA1BP2
2.39e-66FFCP PHASE1:Hg19::chr3:2141775..2141783,-#_7052249764c66f22cd325eeb139b417ep@chr3:2141775..2141783, -
2.39e-66FFCP PHASE2:Hg19::chr3:127441545..127441550,-#_7052249764c66f22cd325eeb139b417ep58@MGLL
2.39e-66FFCP PHASE1:Hg19::chr7:18439468..18439477,+#_7052249764c66f22cd325eeb139b417ep@chr7:18439468..18439477, +
2.39e-66FFCP PHASE1:Hg19::chr18:22251681..22251685,-#_7052249764c66f22cd325eeb139b417ep@chr18:22251681..22251685, -
2.39e-66FFCP PHASE2:Hg19::chr4:169935485..169935488,-#_7052249764c66f22cd325eeb139b417ep@chr4:169935485..169935488, -
2.39e-66FFCP PHASE2:Hg19::chr3:163194047..163194081,-#_7052249764c66f22cd325eeb139b417ep@chr3:163194047..163194081, -
2.39e-66FFCP PHASE1:Hg19::chr13:23733478..23733489,-#_7052249764c66f22cd325eeb139b417ep@chr13:23733478..23733489, -
2.39e-66FFCP PHASE1:Hg19::chr9:18993581..18993586,-#_7052249764c66f22cd325eeb139b417ep@chr9:18993581..18993586, -
2.39e-66FFCP PHASE1:Hg19::chr6:152589452..152589462,-#_7052249764c66f22cd325eeb139b417ep43@SYNE1
2.39e-66FFCP PHASE1:Hg19::chr3:2140207..2140208,+#_7052249764c66f22cd325eeb139b417ep34@CNTN4
2.39e-66FFCP PHASE1:Hg19::chr11:30257128..30257133,-#_7052249764c66f22cd325eeb139b417ep@chr11:30257128..30257133, -
2.39e-66FFCP PHASE2:Hg19::chr10:63700076..63700086,+#_7052249764c66f22cd325eeb139b417ep@chr10:63700076..63700086, +
2.39e-66FFCP PHASE2:Hg19::chr3:157230599..157230604,+#_7052249764c66f22cd325eeb139b417ep@chr3:157230599..157230604, +
2.39e-66FFCP PHASE2:Hg19::chr6:152792957..152792960,-#_7052249764c66f22cd325eeb139b417ep@chr6:152792957..152792960, -
2.39e-66FFCP PHASE2:Hg19::chr11:30253410..30253431,+#_7052249764c66f22cd325eeb139b417ep2@FSHB
2.39e-66FFCP PHASE1:Hg19::chr6:150740842..150740854,+#_7052249764c66f22cd325eeb139b417ep@chr6:150740842..150740854, +
2.39e-66FFCP PHASE1:Hg19::chr4:145124273..145124279,+#_7052249764c66f22cd325eeb139b417ep@chr4:145124273..145124279, +
2.39e-66FFCP PHASE2:Hg19::chr3:2141759..2141771,-#_7052249764c66f22cd325eeb139b417ep@chr3:2141759..2141771, -
2.39e-66FFCP PHASE2:Hg19::chr1:145471703..145471706,+#_7052249764c66f22cd325eeb139b417ep@chr1:145471703..145471706, +
2.39e-66FFCP PHASE1:Hg19::chrX:135338397..135338402,-#_7052249764c66f22cd325eeb139b417ep@chrX:135338397..135338402, -
2.39e-66FFCP PHASE1:Hg19::chr15:96181421..96181428,-#_7052249764c66f22cd325eeb139b417ep@chr15:96181421..96181428, -
2.39e-66FFCP PHASE2:Hg19::chr1:192407879..192407891,-#_7052249764c66f22cd325eeb139b417ep@chr1:192407879..192407891, -
2.39e-66FFCP PHASE2:Hg19::chr10:33244345..33244348,-#_7052249764c66f22cd325eeb139b417ep@chr10:33244345..33244348, -
2.39e-66FFCP PHASE1:Hg19::chr1:154942376..154942386,-#_7052249764c66f22cd325eeb139b417ep@chr1:154942376..154942386, -
2.39e-66FFCP PHASE2:Hg19::chr7:94540075..94540082,+#_7052249764c66f22cd325eeb139b417ep21@PPP1R9A
2.39e-66FFCP PHASE2:Hg19::chr6:152589396..152589401,-#_7052249764c66f22cd325eeb139b417ep68@SYNE1
2.39e-66FFCP PHASE2:Hg19::chr1:198595896..198595910,+#_7052249764c66f22cd325eeb139b417ep@chr1:198595896..198595910, +
2.39e-66FFCP PHASE2:Hg19::chr12:95941674..95941679,+#_7052249764c66f22cd325eeb139b417ep@chr12:95941674..95941679, +
2.39e-66FFCP PHASE2:Hg19::chr3:2140149..2140157,+#_7052249764c66f22cd325eeb139b417ep25@CNTN4
2.39e-66FFCP PHASE1:Hg19::chr8:107074457..107074458,+#_7052249764c66f22cd325eeb139b417ep@chr8:107074457..107074458, +
2.39e-66FFCP PHASE1:Hg19::chr3:1577628..1577634,-#_7052249764c66f22cd325eeb139b417ep@chr3:1577628..1577634, -
2.39e-66FFCP PHASE1:Hg19::chr4:72897846..72897853,+#_7052249764c66f22cd325eeb139b417ep7@NPFFR2
2.39e-66FFCP PHASE1:Hg19::chr3:2141862..2141887,-#_7052249764c66f22cd325eeb139b417ep@chr3:2141862..2141887, -
2.39e-66FFCP PHASE2:Hg19::chr14:83319766..83319776,-#_7052249764c66f22cd325eeb139b417ep@chr14:83319766..83319776, -
2.39e-66FFCP PHASE1:Hg19::chr21:17357327..17357329,-#_7052249764c66f22cd325eeb139b417ep@chr21:17357327..17357329, -
2.39e-66FFCP PHASE2:Hg19::chr12:79920595..79920605,-#_7052249764c66f22cd325eeb139b417ep@chr12:79920595..79920605, -
2.39e-66FFCP PHASE1:Hg19::chr18:22253588..22253590,+#_7052249764c66f22cd325eeb139b417ep@chr18:22253588..22253590, +
2.39e-66FFCP PHASE2:Hg19::chr3:177555440..177555446,-#_7052249764c66f22cd325eeb139b417ep@chr3:177555440..177555446, -
2.39e-66FFCP PHASE2:Hg19::chr15:96181408..96181419,-#_7052249764c66f22cd325eeb139b417ep@chr15:96181408..96181419, -
2.39e-66FFCP PHASE1:Hg19::chr7:80080929..80080934,+#_7052249764c66f22cd325eeb139b417ep@chr7:80080929..80080934, +
2.39e-66FFCP PHASE1:Hg19::chr3:157221979..157222025,-#_7052249764c66f22cd325eeb139b417ep@chr3:157221979..157222025, -
2.39e-66FFCP PHASE1:Hg19::chr6:152592460..152592465,-#_7052249764c66f22cd325eeb139b417ep@chr6:152592460..152592465, -
2.39e-66FFCP PHASE2:Hg19::chr1:154942216..154942223,-#_7052249764c66f22cd325eeb139b417ep@chr1:154942216..154942223, -
2.39e-66FFCP PHASE2:Hg19::chr6:150735340..150735361,+#_7052249764c66f22cd325eeb139b417ep@chr6:150735340..150735361, +
2.39e-66FFCP PHASE2:Hg19::chr3:1577586..1577600,-#_7052249764c66f22cd325eeb139b417ep@chr3:1577586..1577600, -
2.39e-66FFCP PHASE2:Hg19::chr18:74961699..74961708,+#_7052249764c66f22cd325eeb139b417ep5@GALR1
2.39e-66FFCP PHASE1:Hg19::chr9:18504821..18504825,+#_7052249764c66f22cd325eeb139b417ep@chr9:18504821..18504825, +
2.39e-66FFCP PHASE1:Hg19::chr6:152589315..152589320,-#_7052249764c66f22cd325eeb139b417ep72@SYNE1
2.39e-66FFCP PHASE1:Hg19::chr4:169935453..169935460,-#_7052249764c66f22cd325eeb139b417ep@chr4:169935453..169935460, -
2.39e-66FFCP PHASE2:Hg19::chr3:2141851..2141858,-#_7052249764c66f22cd325eeb139b417ep@chr3:2141851..2141858, -
2.39e-66FFCP PHASE1:Hg19::chr3:196296715..196296737,-#_7052249764c66f22cd325eeb139b417ep@chr3:196296715..196296737, -
2.39e-66FFCP PHASE1:Hg19::chr2:206927691..206927699,-#_7052249764c66f22cd325eeb139b417ep@chr2:206927691..206927699, -
2.39e-66FFCP PHASE1:Hg19::chr12:79920595..79920605,-#_7052249764c66f22cd325eeb139b417ep@chr12:79920595..79920605, -
2.39e-66FFCP PHASE2:Hg19::chr2:188420455..188420469,+#_7052249764c66f22cd325eeb139b417ep@chr2:188420455..188420469, +
2.39e-66FFCP PHASE1:Hg19::chrX:135338270..135338275,-#_7052249764c66f22cd325eeb139b417ep@chrX:135338270..135338275, -

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