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UBERON:0001911

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Name:mammary gland
Definition:"The specialized accessory gland of the skin of female mammals that secretes milk. In the human female, it is a compound tubuloalveolar gland composed of 15 to 25 lobes arranged radially about the nipple and separated by connective and adipose tissue, each lobe having its own excretory (lactiferous) duct opening on the nipple. The lobes are subdivided into lobules, with the alveolar ducts and alveoli being the secretory portion of the gland[BTO]. The mouse forms five to six pairs of mammary glands that extend from the neck to the groin." [BTO:0000817, Wikipedia:Mammary_gland]
Xrefs:
links:

BTO:0000817
EFO:0000854
EMAPA:17759
EV:0100125
[1]
[2]
MA:0000145
MAT:0000073
MESH:A.10.336.482
MIAA:0000073
ncithesaurus:Mammary_Gland
OpenCyc:Mx4rvVjVq5wpEbGdrcN5Y29ycA
SCTID:361720005

VHOG:0000398
Synonyms: "Brustdruese" RELATED [BTO:0000817]
"dug" RELATED [Wikipedia:Mammary_gland]
"glandula mammaria" EXACT PLURAL [FMA:57983, FMA:TA]
"glandula mammaria" RELATED LATIN [Wikipedia:Mammary_gland]
"lactiferous gland" EXACT [FMA:62088]
"lobe of breast" EXACT []
"lobe of mammary gland" EXACT []
"mamma" RELATED [BTO:0000817]
Comments:Note that this class corresponds to the generic mammary gland. The human mammary gland is in the thoracic/breast region and is therefore covered by the subclass "thoracic mammary gland" // Males typically only have rudimentary mammary glands, The male Dayak fruit bat has lactating mammary glands. Male lactation occurs infrequently in some species. We make a part_of association to female organism for now as this is the canonical case
Alt_id: UBERON:FMA_62088-MA_0000145-MIAA_0000073-Mammary
Subset: organ_slim
uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0002365(exocrine gland),UBERON:0003297(gland of integumental system),UBERON:0004121(ectoderm-derived structure)
develops_from:UBERON:0005333(mammary bud)
part_of:UBERON:0002416(integumental system)



Children

derives from:FF:0011387 (mouse mammary gland- adult pregnant day19 sample),FF:0011390 (mouse mammary gland- adult lactating day02 sample),FF:0103568 (mammary gland cell line sample)
part of:CL:0002327 (mammary gland epithelial cell),CL:0002555 (fibroblast of mammary gland)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001911 (mammary gland), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
5.72e-89FFCP PHASE1:Hg19::chr12:122439564..122439597,+#_173f871008b680d3280aa96735ce001bp4@WDR66
5.72e-89FFCP PHASE2:Hg19::chr12:122439564..122439597,+#_173f871008b680d3280aa96735ce001bp4@WDR66
2.57e-88FFCP PHASE2:Hg19::chr19:15160255..15160260,+#_ddb3644517137af0adb0c82b250e1149p4@CASP14
2.57e-88FFCP PHASE1:Hg19::chr19:15160255..15160260,+#_ddb3644517137af0adb0c82b250e1149p4@CASP14
1.87e-86FFCP PHASE2:Mm9::chr10:100283528..100283529,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr10:100283528..100283529, +
1.87e-86FFCP PHASE1:Mm9::chr5:88206236..88206252,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88206236..88206252, +
1.87e-86FFCP PHASE1:Mm9::chr5:88095990..88096001,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88095990..88096001, +
1.87e-86FFCP PHASE1:Mm9::chr15:98557870..98557874,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr15:98557870..98557874, -
1.87e-86FFCP PHASE2:Mm9::chr11:48162734..48162736,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr11:48162734..48162736, -
1.87e-86FFCP PHASE2:Mm9::chr5:88215663..88215674,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88215663..88215674, +
1.87e-86FFCP PHASE1:Mm9::chr8:39536780..39536784,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr8:39536780..39536784, -
1.87e-86FFCP PHASE2:Mm9::chr4:116740698..116740723,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr4:116740698..116740723, +
1.87e-86FFCP PHASE1:Mm9::chr5:88217723..88217733,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88217723..88217733, +
1.87e-86FFCP PHASE1:Mm9::chr5:88121676..88121704,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88121676..88121704, -
1.87e-86FFCP PHASE2:Mm9::chr5:88359009..88359014,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88359009..88359014, -
1.87e-86FFCP PHASE1:Mm9::chr6:104295805..104295814,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr6:104295805..104295814, +
1.87e-86FFCP PHASE1:Mm9::chr5:88125078..88125099,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88125078..88125099, -
1.87e-86FFCP PHASE1:Mm9::chr11:121057666..121057669,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr11:121057666..121057669, -
1.87e-86FFCP PHASE2:Mm9::chr15:103393258..103393296,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr15:103393258..103393296, +
1.87e-86FFCP PHASE2:Mm9::chr5:88100053..88100078,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88100053..88100078, -
1.87e-86FFCP PHASE2:Mm9::chr9:77686699..77686701,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr9:77686699..77686701, +
1.87e-86FFCP PHASE2:Mm9::chr5:88210886..88210920,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88210886..88210920, -
1.87e-86FFCP PHASE2:Mm9::chr8:8021158..8021161,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr8:8021158..8021161, -
1.87e-86FFCP PHASE1:Mm9::chr4:118637931..118637942,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p7@Lao1
1.87e-86FFCP PHASE2:Mm9::chr15:15105208..15105219,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr15:15105208..15105219, -
1.87e-86FFCP PHASE2:Mm9::chr5:88121763..88121767,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88121763..88121767, -
1.87e-86FFCP PHASE1:Mm9::chr5:88215632..88215662,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88215632..88215662, +
1.87e-86FFCP PHASE1:Mm9::chr5:88107092..88107108,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88107092..88107108, -
1.87e-86FFCP PHASE1:Mm9::chr19:4104421..4104423,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr19:4104421..4104423, +
1.87e-86FFCP PHASE1:Mm9::chr10:46245998..46245999,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr10:46245998..46245999, +
1.87e-86FFCP PHASE2:Mm9::chr2:140424221..140424232,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr2:140424221..140424232, +
1.87e-86FFCP PHASE1:Mm9::chr7:112544745..112544756,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr7:112544745..112544756, -
1.87e-86FFCP PHASE1:Mm9::chr4:62394478..62394481,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr4:62394478..62394481, -
1.87e-86FFCP PHASE1:Mm9::chr15:15105208..15105219,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr15:15105208..15105219, -
1.87e-86FFCP PHASE2:Mm9::chr5:88124293..88124295,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88124293..88124295, -
1.87e-86FFCP PHASE1:Mm9::chr5:88358983..88358986,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88358983..88358986, +
1.87e-86FFCP PHASE1:Mm9::chr5:88123793..88123819,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88123793..88123819, +
1.87e-86FFCP PHASE2:Mm9::chr5:88096251..88096262,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88096251..88096262, +
1.87e-86FFCP PHASE1:Mm9::chr5:38893329..38893340,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p8@Slc2a9
1.87e-86FFCP PHASE1:Mm9::chr4:118627429..118627443,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p1@ENSMUST00000155069, p1@uc008ulc.1
1.87e-86FFCP PHASE1:Mm9::chr11:6536708..6536724,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr11:6536708..6536724, +
1.87e-86FFCP PHASE2:Mm9::chr15:103393812..103393824,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr15:103393812..103393824, -
1.87e-86FFCP PHASE2:Mm9::chr5:88108071..88108075,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88108071..88108075, -
1.87e-86FFCP PHASE1:Mm9::chr5:88210852..88210888,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88210852..88210888, +
1.87e-86FFCP PHASE1:Mm9::chr5:88103101..88103120,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88103101..88103120, -
1.87e-86FFCP PHASE1:Mm9::chr19:17975686..17975688,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr19:17975686..17975688, -
1.87e-86FFCP PHASE2:Mm9::chr5:88356056..88356074,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88356056..88356074, +
1.87e-86FFCP PHASE1:Mm9::chr15:103393703..103393706,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr15:103393703..103393706, -
1.87e-86FFCP PHASE2:Mm9::chr4:118627452..118627463,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p2@ENSMUST00000155069, p2@uc008ulc.1
1.87e-86FFCP PHASE2:Mm9::chr8:67022646..67022651,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr8:67022646..67022651, +
1.87e-86FFCP PHASE1:Mm9::chr5:88358835..88358840,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88358835..88358840, +
1.87e-86FFCP PHASE1:Mm9::chr5:88123674..88123680,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88123674..88123680, -
1.87e-86FFCP PHASE2:Mm9::chr4:118640438..118640443,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr4:118640438..118640443, +
1.87e-86FFCP PHASE1:Mm9::chr5:151567427..151567434,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p10@Pds5b
1.87e-86FFCP PHASE2:Mm9::chr5:88209128..88209157,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88209128..88209157, +
1.87e-86FFCP PHASE2:Mm9::chr15:103393361..103393372,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr15:103393361..103393372, -
1.87e-86FFCP PHASE2:Mm9::chr5:88103215..88103245,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88103215..88103245, +
1.87e-86FFCP PHASE2:Mm9::chr9:107419666..107419669,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr9:107419666..107419669, -
1.87e-86FFCP PHASE1:Mm9::chr9:77686637..77686644,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr9:77686637..77686644, +
1.87e-86FFCP PHASE1:Mm9::chr5:88209021..88209051,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88209021..88209051, +
1.87e-86FFCP PHASE1:Mm9::chr5:88098006..88098035,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88098006..88098035, +
1.87e-86FFCP PHASE1:Mm9::chr1:23404398..23404401,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p1@uc007amc.1
1.87e-86FFCP PHASE1:Mm9::chr18:6733891..6733896,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr18:6733891..6733896, +
1.87e-86FFCP PHASE2:Mm9::chr4:62394478..62394481,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr4:62394478..62394481, -
1.87e-86FFCP PHASE2:Mm9::chr5:88217642..88217646,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88217642..88217646, -
1.87e-86FFCP PHASE1:Mm9::chr15:103393256..103393264,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr15:103393256..103393264, -
1.87e-86FFCP PHASE2:Mm9::chr11:6535581..6535586,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr11:6535581..6535586, -
1.87e-86FFCP PHASE2:Mm9::chr5:88123649..88123664,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88123649..88123664, -
1.87e-86FFCP PHASE1:Mm9::chr5:88123526..88123536,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88123526..88123536, +
1.87e-86FFCP PHASE1:Mm9::chr11:100614219..100614221,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr11:100614219..100614221, -
1.87e-86FFCP PHASE2:Mm9::chr5:88204836..88204843,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88204836..88204843, +
1.87e-86FFCP PHASE2:Mm9::chr14:30342837..30342838,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr14:30342837..30342838, -
1.87e-86FFCP PHASE1:Mm9::chr5:88127079..88127081,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88127079..88127081, -
1.87e-86FFCP PHASE1:Mm9::chr2:151795763..151795765,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr2:151795763..151795765, +
1.87e-86FFCP PHASE1:Mm9::chr4:118634471..118634476,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p9@Lao1
1.87e-86FFCP PHASE1:Mm9::chr15:98312638..98312662,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr15:98312638..98312662, -
1.87e-86FFCP PHASE2:Mm9::chr15:98312638..98312662,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr15:98312638..98312662, -
1.87e-86FFCP PHASE2:Mm9::chr1:40637185..40637194,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p6@Slc9a4
1.87e-86FFCP PHASE2:Mm9::chr5:88214331..88214347,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88214331..88214347, -
1.87e-86FFCP PHASE1:Mm9::chr4:118641223..118641237,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr4:118641223..118641237, -
1.87e-86FFCP PHASE2:Mm9::chr5:88123539..88123551,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88123539..88123551, +
1.87e-86FFCP PHASE1:Mm9::chr5:88215700..88215705,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88215700..88215705, +
1.87e-86FFCP PHASE1:Mm9::chr5:88109913..88109924,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88109913..88109924, -
1.87e-86FFCP PHASE2:Mm9::chr18:6733951..6733958,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr18:6733951..6733958, +
1.87e-86FFCP PHASE2:Mm9::chr13:23550306..23550308,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr13:23550306..23550308, -
1.87e-86FFCP PHASE2:Mm9::chr2:28416848..28416860,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr2:28416848..28416860, -
1.87e-86FFCP PHASE2:Mm9::chr5:88358934..88358941,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88358934..88358941, +
1.87e-86FFCP PHASE2:Mm9::chr18:27904115..27904120,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr18:27904115..27904120, +
1.87e-86FFCP PHASE2:Mm9::chr5:88126303..88126323,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88126303..88126323, -
1.87e-86FFCP PHASE1:Mm9::chr5:88361418..88361423,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88361418..88361423, +
1.87e-86FFCP PHASE1:Mm9::chr19:56051165..56051186,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr19:56051165..56051186, +
1.87e-86FFCP PHASE2:Mm9::chr5:88098535..88098555,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88098535..88098555, +
1.87e-86FFCP PHASE2:Mm9::chr5:53448964..53448972,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p4@Slc34a2
1.87e-86FFCP PHASE2:Mm9::chr5:88210832..88210837,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88210832..88210837, +
1.87e-86FFCP PHASE2:Mm9::chr14:32247505..32247512,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr14:32247505..32247512, -
1.87e-86FFCP PHASE1:Mm9::chr4:118636782..118636786,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr4:118636782..118636786, +
1.87e-86FFCP PHASE2:Mm9::chr12:52131128..52131133,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr12:52131128..52131133, -
1.87e-86FFCP PHASE2:Mm9::chr5:88109964..88109969,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88109964..88109969, -
1.87e-86FFCP PHASE1:Mm9::chr5:88213608..88213623,-#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88213608..88213623, -
1.87e-86FFCP PHASE1:Mm9::chr5:88106054..88106056,+#_2557a8a1e7da94ec95c1dd5c3173b4f2p@chr5:88106054..88106056, +

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