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UBERON:0002423

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Name:hepatobiliary system
Definition:"The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. The parts are: liver, bile duct, gall bladder and hepatic duct" [GO:0061008, Wikipedia:Hepatobiliary_system]
Xrefs:
links:

AAO:0011056
EFO:0000800
EHDAA2:0000998
EHDAA:2189
EMAPA:16840
EV:0100088
MA:0000324
MAT:0000024
MIAA:0000024
ncithesaurus:Hepatobiliary_System
TAO:0000036
VHOG:0000294
XAO:0000132

ZFA:0000036
Synonyms: "hepaticobiliary system" EXACT [GO:0061008]
"liver and biliary system" EXACT []
"liver/biliary system" RELATED []
Alt_id: UBERON:MA_0000324-MIAA_0000024-XAO_0000132-ZFA_0000036
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0000467(anatomical system)
disjoint_from:UBERON:0004456(entire sense organ system)
part_of:UBERON:0001007(digestive system)



Children

disjoint from:UBERON:0000949 (endocrine system),UBERON:0000990 (reproductive system),UBERON:0001004 (respiratory system),UBERON:0001007 (digestive system),UBERON:0001008 (renal system),UBERON:0001009 (circulatory system),UBERON:0001016 (nervous system),UBERON:0001033 (gustatory system),UBERON:0001434 (skeletal system),UBERON:0002204 (musculoskeletal system),UBERON:0002294 (biliary system),UBERON:0002330 (exocrine system),UBERON:0002390 (hematopoietic system),UBERON:0002405 (immune system),UBERON:0002416 (integumental system)
part of:UBERON:0002107 (liver),UBERON:0002294 (biliary system),UBERON:0006242 (gall bladder primordium)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002423 (hepatobiliary system), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
9.2e-75FFCP PHASE1:Hg19::chr12:100867777..100867788,+#_50685c1a122cfcea578e5a54a79ed2a7p5@NR1H4
9.2e-75FFCP PHASE2:Hg19::chr12:100867777..100867788,+#_50685c1a122cfcea578e5a54a79ed2a7p5@NR1H4
1.22e-72FFCP PHASE2:Mm9::chr5:90897694..90897705,+#_036f6cc1a5e701c109b055e5c5e937f2p@chr5:90897694..90897705, +
1.22e-72FFCP PHASE1:Mm9::chr5:90897694..90897705,+#_036f6cc1a5e701c109b055e5c5e937f2p@chr5:90897694..90897705, +
2.2e-72FFCP PHASE1:Mm9::chr19:25169885..25169900,+#_8478393a8c80004de0d9570c57881b2cp@chr19:25169885..25169900, +
2.2e-72FFCP PHASE2:Mm9::chr19:25169885..25169900,+#_8478393a8c80004de0d9570c57881b2cp@chr19:25169885..25169900, +
5.51e-71FFCP PHASE2:Mm9::chr7:121912281..121912295,+#_66e04aebf2f15d6dba84d7205e982efdp6@Insc
5.51e-71FFCP PHASE1:Mm9::chr7:121912281..121912295,+#_66e04aebf2f15d6dba84d7205e982efdp6@Insc
1.64e-70FFCP PHASE2:Hg19::chr20:10349456..10349475,-#_010eaed44ff31bda26faa56af1d63192p1@ENST00000421143
1.64e-70FFCP PHASE1:Hg19::chr20:10349456..10349475,-#_010eaed44ff31bda26faa56af1d63192p1@ENST00000421143
1.7e-70FFCP PHASE2:Mm9::chr8:131012371..131012382,-#_35df1a35e3786284129489b017ba2276p2@uc009nzu.1
1.7e-70FFCP PHASE1:Mm9::chr8:131012371..131012382,-#_35df1a35e3786284129489b017ba2276p2@uc009nzu.1
1.28e-68FFCP PHASE2:Mm9::chr13:94407586..94407604,-#_453a61f97b964dd9921a8a486cfbf175p5@Bhmt
1.28e-68FFCP PHASE1:Mm9::chr13:94407586..94407604,-#_453a61f97b964dd9921a8a486cfbf175p5@Bhmt
2.72e-68FFCP PHASE1:Mm9::chr1:162917234..162917248,+#_3dde74ed131a8cdea8f7de72d4b0567dp@chr1:162917234..162917248, +
2.72e-68FFCP PHASE2:Mm9::chr1:162917234..162917248,+#_3dde74ed131a8cdea8f7de72d4b0567dp@chr1:162917234..162917248, +
3.5e-68FFCP PHASE2:Mm9::chr9:110892216..110892232,-#_b161fbf10edc8f8670a9e1968f8c95dap1@Rtp3
3.5e-68FFCP PHASE1:Mm9::chr9:110892216..110892232,-#_b161fbf10edc8f8670a9e1968f8c95dap1@Rtp3
2.47e-67FFCP PHASE2:Mm9::chr9:110892239..110892252,-#_0b92b2539a35667f26797fe971abe74bp2@Rtp3
2.47e-67FFCP PHASE1:Mm9::chr9:110892239..110892252,-#_0b92b2539a35667f26797fe971abe74bp2@Rtp3
2.47e-67FFCP PHASE2:Mm9::chr7:112744083..112744109,-#_0b92b2539a35667f26797fe971abe74bp@chr7:112744083..112744109, -
2.47e-67FFCP PHASE1:Mm9::chr7:112744083..112744109,-#_0b92b2539a35667f26797fe971abe74bp@chr7:112744083..112744109, -
6.55e-67FFCP PHASE2:Mm9::chr13:23928766..23928779,+#_2b8cc88b5ac8f541a6859885395d9345p@chr13:23928766..23928779, +
6.55e-67FFCP PHASE1:Mm9::chr13:23928766..23928779,+#_2b8cc88b5ac8f541a6859885395d9345p@chr13:23928766..23928779, +
7.85e-67FFCP PHASE1:Mm9::chr7:28237436..28237488,+#_cd4c8b628ec0a4701291cf653bff5e6ap3@Blvrb
7.85e-67FFCP PHASE2:Mm9::chr7:28237436..28237488,+#_cd4c8b628ec0a4701291cf653bff5e6ap3@Blvrb
1.58e-66FFCP PHASE2:Mm9::chr12:105004018..105004046,-#_6490f6682992f1049ca87290d6d6b726p@chr12:105004018..105004046, -
1.58e-66FFCP PHASE1:Mm9::chr2:10041210..10041222,-#_6490f6682992f1049ca87290d6d6b726p@chr2:10041210..10041222, -
1.58e-66FFCP PHASE1:Mm9::chr16:22898981..22898988,-#_6490f6682992f1049ca87290d6d6b726p@chr16:22898981..22898988, -
1.58e-66FFCP PHASE2:Mm9::chr16:22898981..22898988,-#_6490f6682992f1049ca87290d6d6b726p@chr16:22898981..22898988, -
1.58e-66FFCP PHASE2:Mm9::chr6:128436166..128436185,-#_6490f6682992f1049ca87290d6d6b726p@chr6:128436166..128436185, -
1.58e-66FFCP PHASE2:Mm9::chr2:10041210..10041222,-#_6490f6682992f1049ca87290d6d6b726p@chr2:10041210..10041222, -
1.58e-66FFCP PHASE2:Mm9::chr16:22894900..22894910,+#_6490f6682992f1049ca87290d6d6b726p@chr16:22894900..22894910, +
1.58e-66FFCP PHASE1:Mm9::chr12:105004018..105004046,-#_6490f6682992f1049ca87290d6d6b726p@chr12:105004018..105004046, -
1.58e-66FFCP PHASE1:Mm9::chr6:128436166..128436185,-#_6490f6682992f1049ca87290d6d6b726p@chr6:128436166..128436185, -
1.58e-66FFCP PHASE1:Mm9::chr16:22894900..22894910,+#_6490f6682992f1049ca87290d6d6b726p@chr16:22894900..22894910, +
1.17e-64FFCP PHASE1:Mm9::chr1:173155793..173155841,+#_1ed7c0a00e32c92493dda75ddee578a4p@chr1:173155793..173155841, +
1.17e-64FFCP PHASE2:Mm9::chr1:173155793..173155841,+#_1ed7c0a00e32c92493dda75ddee578a4p@chr1:173155793..173155841, +
1.34e-64FFCP PHASE1:Mm9::chr17:12588483..12588503,+#_c26d16cbea3160236e618ea504e6805cp@chr17:12588483..12588503, +
1.34e-64FFCP PHASE2:Mm9::chr17:12588483..12588503,+#_c26d16cbea3160236e618ea504e6805cp@chr17:12588483..12588503, +
1.38e-64FFCP PHASE1:Mm9::chr17:12584645..12584657,+#_571cd25dc214c64c181665580e0d63f0p@chr17:12584645..12584657, +
1.38e-64FFCP PHASE2:Mm9::chr17:12584645..12584657,+#_571cd25dc214c64c181665580e0d63f0p@chr17:12584645..12584657, +
1.62e-64FFCP PHASE1:Mm9::chr1:166179426..166179437,+#_c7b4002a3bc3e9bd738aaed8f40bd1a6p@chr1:166179426..166179437, +
1.62e-64FFCP PHASE2:Mm9::chr1:166179426..166179437,+#_c7b4002a3bc3e9bd738aaed8f40bd1a6p@chr1:166179426..166179437, +
1.68e-64FFCP PHASE1:Mm9::chr8:34917332..34917357,-#_aa7ec451e222de1170875fb8569ce136p@chr8:34917332..34917357, -
1.68e-64FFCP PHASE2:Mm9::chr8:34917332..34917357,-#_aa7ec451e222de1170875fb8569ce136p@chr8:34917332..34917357, -
4.38e-64FFCP PHASE1:Mm9::chr19:38191263..38191291,-#_c562660c65a52b8e2a16b73a52b8a80ap@chr19:38191263..38191291, -
4.38e-64FFCP PHASE2:Mm9::chr19:38191263..38191291,-#_c562660c65a52b8e2a16b73a52b8a80ap@chr19:38191263..38191291, -
9.3e-64FFCP PHASE1:Mm9::chr7:121912266..121912277,+#_0ba89d73cfb098cb53f2225e2a4ef877p8@Insc
9.3e-64FFCP PHASE2:Mm9::chr7:121912266..121912277,+#_0ba89d73cfb098cb53f2225e2a4ef877p8@Insc
1.1e-63FFCP PHASE2:Mm9::chr5:90893974..90893978,+#_90b49b49dc8e672bb07267b61387bd15p@chr5:90893974..90893978, +
1.1e-63FFCP PHASE1:Mm9::chr5:90893974..90893978,+#_90b49b49dc8e672bb07267b61387bd15p@chr5:90893974..90893978, +
1.7e-63FFCP PHASE1:Mm9::chr8:131012475..131012492,-#_2b392766190a5d9d12a595d95c6a1dc3p1@uc009nzu.1
1.7e-63FFCP PHASE2:Mm9::chr8:131012475..131012492,-#_2b392766190a5d9d12a595d95c6a1dc3p1@uc009nzu.1
1.85e-63FFCP PHASE1:Mm9::chr8:46380208..46380217,-#_026ba462b614500e20efbd0251678217p3@Klkb1
1.85e-63FFCP PHASE2:Mm9::chr8:46380208..46380217,-#_026ba462b614500e20efbd0251678217p3@Klkb1
2.02e-63FFCP PHASE2:Mm9::chr3:57191661..57191672,-#_3fbe4ef99b529f557ad2a11bac10f3bap@chr3:57191661..57191672, -
2.02e-63FFCP PHASE1:Mm9::chr3:57191661..57191672,-#_3fbe4ef99b529f557ad2a11bac10f3bap@chr3:57191661..57191672, -
2.18e-63FFCP PHASE2:Mm9::chr17:12583153..12583171,+#_d6d8b1e8213f67893b5852b50a53fa13p@chr17:12583153..12583171, +
2.18e-63FFCP PHASE1:Mm9::chr17:12583153..12583171,+#_d6d8b1e8213f67893b5852b50a53fa13p@chr17:12583153..12583171, +
2.2e-63FFCP PHASE2:Mm9::chr3:82814412..82814431,+#_29b9432a1654c1ce8312a972b3fabbd9p@chr3:82814412..82814431, +
2.2e-63FFCP PHASE1:Mm9::chr3:82814412..82814431,+#_29b9432a1654c1ce8312a972b3fabbd9p@chr3:82814412..82814431, +
3.67e-63FFCP PHASE1:Mm9::chr5:93000570..93000589,+#_59bfd12c416f1ef4675222208f61641ep3@Fam47e
3.67e-63FFCP PHASE2:Mm9::chr5:93000570..93000589,+#_59bfd12c416f1ef4675222208f61641ep3@Fam47e
5.17e-63FFCP PHASE2:Mm9::chr16:22895330..22895339,-#_44676bc187fab31abfb2d02970ecab58p@chr16:22895330..22895339, -
5.17e-63FFCP PHASE1:Mm9::chr16:22895330..22895339,-#_44676bc187fab31abfb2d02970ecab58p@chr16:22895330..22895339, -
5.17e-63FFCP PHASE2:Mm9::chr8:92849825..92849837,-#_44676bc187fab31abfb2d02970ecab58p@chr8:92849825..92849837, -
5.17e-63FFCP PHASE1:Mm9::chr15:77605636..77605639,+#_44676bc187fab31abfb2d02970ecab58p@chr15:77605636..77605639, +
5.17e-63FFCP PHASE1:Mm9::chr3:82835513..82835525,+#_44676bc187fab31abfb2d02970ecab58p@chr3:82835513..82835525, +
5.17e-63FFCP PHASE2:Mm9::chr3:82835513..82835525,+#_44676bc187fab31abfb2d02970ecab58p@chr3:82835513..82835525, +
5.17e-63FFCP PHASE1:Mm9::chr16:23449901..23449906,-#_44676bc187fab31abfb2d02970ecab58p@chr16:23449901..23449906, -
5.17e-63FFCP PHASE1:Mm9::chr8:92849825..92849837,-#_44676bc187fab31abfb2d02970ecab58p@chr8:92849825..92849837, -
5.17e-63FFCP PHASE2:Mm9::chr15:77605636..77605639,+#_44676bc187fab31abfb2d02970ecab58p@chr15:77605636..77605639, +
5.17e-63FFCP PHASE2:Mm9::chr16:23449901..23449906,-#_44676bc187fab31abfb2d02970ecab58p@chr16:23449901..23449906, -
6.19e-63FFCP PHASE1:Mm9::chr16:22896674..22896687,-#_d1e3e5fed26e28ba9f1631b0765e93acp@chr16:22896674..22896687, -
6.19e-63FFCP PHASE2:Mm9::chr16:22896674..22896687,-#_d1e3e5fed26e28ba9f1631b0765e93acp@chr16:22896674..22896687, -
6.77e-63FFCP PHASE1:Mm9::chr17:12577256..12577270,+#_62a6fadafd436e7d1cef0fd00c49e74fp@chr17:12577256..12577270, +
6.77e-63FFCP PHASE2:Mm9::chr17:12577256..12577270,+#_62a6fadafd436e7d1cef0fd00c49e74fp@chr17:12577256..12577270, +
6.95e-63FFCP PHASE1:Mm9::chr17:32822530..32822541,+#_90c98ac5b6a56c8b3ec8e35f50902d9fp2@Cyp4f15
6.95e-63FFCP PHASE2:Mm9::chr17:32822530..32822541,+#_90c98ac5b6a56c8b3ec8e35f50902d9fp2@Cyp4f15
7.62e-63FFCP PHASE1:Hg19::chr8:144417558..144417572,-#_542ae4842fb3b5350fe48756519d69a7p7@TOP1MT
7.62e-63FFCP PHASE2:Hg19::chr2:21233797..21233804,-#_542ae4842fb3b5350fe48756519d69a7p58@APOB
7.62e-63FFCP PHASE1:Hg19::chr2:21233797..21233804,-#_542ae4842fb3b5350fe48756519d69a7p58@APOB
7.62e-63FFCP PHASE2:Hg19::chr8:144417558..144417572,-#_542ae4842fb3b5350fe48756519d69a7p7@TOP1MT
9.86e-63FFCP PHASE1:Mm9::chr11:60622345..60622377,-#_0c5414ee677db1edec1f9d1b7b14f891p@chr11:60622345..60622377, -
9.86e-63FFCP PHASE2:Mm9::chr11:60622345..60622377,-#_0c5414ee677db1edec1f9d1b7b14f891p@chr11:60622345..60622377, -
1.39e-62FFCP PHASE1:Mm9::chr16:22899236..22899246,+#_5832bbecf7f5cdd38de9f472a674b854p@chr16:22899236..22899246, +
1.39e-62FFCP PHASE1:Mm9::chr16:22899322..22899331,+#_5832bbecf7f5cdd38de9f472a674b854p@chr16:22899322..22899331, +
1.39e-62FFCP PHASE1:Mm9::chr16:22895286..22895297,-#_5832bbecf7f5cdd38de9f472a674b854p@chr16:22895286..22895297, -
1.39e-62FFCP PHASE2:Mm9::chr16:22895286..22895297,-#_5832bbecf7f5cdd38de9f472a674b854p@chr16:22895286..22895297, -
1.39e-62FFCP PHASE1:Mm9::chr6:128438012..128438027,-#_5832bbecf7f5cdd38de9f472a674b854p@chr6:128438012..128438027, -
1.39e-62FFCP PHASE1:Mm9::chr12:105002005..105002050,-#_5832bbecf7f5cdd38de9f472a674b854p@chr12:105002005..105002050, -
1.39e-62FFCP PHASE2:Mm9::chr6:11948347..11948351,-#_5832bbecf7f5cdd38de9f472a674b854p@chr6:11948347..11948351, -
1.39e-62FFCP PHASE1:Mm9::chr6:128436196..128436215,-#_5832bbecf7f5cdd38de9f472a674b854p@chr6:128436196..128436215, -
1.39e-62FFCP PHASE2:Mm9::chr6:128438012..128438027,-#_5832bbecf7f5cdd38de9f472a674b854p@chr6:128438012..128438027, -
1.39e-62FFCP PHASE2:Mm9::chr12:105066241..105066272,-#_5832bbecf7f5cdd38de9f472a674b854p1@Serpina1b
1.39e-62FFCP PHASE2:Mm9::chr3:82847318..82847329,-#_5832bbecf7f5cdd38de9f472a674b854p@chr3:82847318..82847329, -
1.39e-62FFCP PHASE1:Mm9::chr12:105066241..105066272,-#_5832bbecf7f5cdd38de9f472a674b854p1@Serpina1b
1.39e-62FFCP PHASE1:Mm9::chr3:82847318..82847329,-#_5832bbecf7f5cdd38de9f472a674b854p@chr3:82847318..82847329, -
1.39e-62FFCP PHASE2:Mm9::chr12:105002005..105002050,-#_5832bbecf7f5cdd38de9f472a674b854p@chr12:105002005..105002050, -

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