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MCL coexpression mm9:591

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:22063208..22063220,+p@chr10:22063208..22063220
+
Mm9::chr11:6192633..6192653,+p8@Ogdh
Mm9::chr11:6192671..6192695,+p4@Ogdh
Mm9::chr11:6192857..6192873,+p@chr11:6192857..6192873
+
Mm9::chr11:6192879..6192901,+p@chr11:6192879..6192901
+
Mm9::chr11:95686449..95686463,+p@chr11:95686449..95686463
+
Mm9::chr1:74063293..74063302,-p@chr1:74063293..74063302
-
Mm9::chr1:74063339..74063352,-p@chr1:74063339..74063352
-
Mm9::chr1:74154930..74154944,-p@chr1:74154930..74154944
-
Mm9::chr2:30270958..30270969,-p9@Crat
Mm9::chr8:42102103..42102121,-p7@Mtus1
Mm9::chrX:156576256..156576268,-p3@Pdha1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0016624oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor5.29291857872747e-05
GO:0005739mitochondrion0.000224485943461562
GO:0016903oxidoreductase activity, acting on the aldehyde or oxo group of donors0.00048344881914575
GO:0006096glycolysis0.00048344881914575
GO:0006007glucose catabolic process0.00048344881914575
GO:0046365monosaccharide catabolic process0.00048344881914575
GO:0019320hexose catabolic process0.00048344881914575
GO:0046164alcohol catabolic process0.00048344881914575
GO:0044275cellular carbohydrate catabolic process0.000598117729282579
GO:0016052carbohydrate catabolic process0.000641168179667001
GO:0006006glucose metabolic process0.00105982972717645
GO:0004092carnitine O-acetyltransferase activity0.00117999570144423
GO:0050164oxoglutarate dehydrogenase (NADP+) activity0.00117999570144423
GO:0019318hexose metabolic process0.00148344954783774
GO:0005996monosaccharide metabolic process0.00148344954783774
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity0.00191733542995084
GO:0004738pyruvate dehydrogenase activity0.00242169834513759
GO:0030976thiamin pyrophosphate binding0.00242169834513759
GO:0004739pyruvate dehydrogenase (acetyl-transferring) activity0.00242169834513759
GO:0044444cytoplasmic part0.00275277858356794
GO:0016413O-acetyltransferase activity0.00284126494223344
GO:0044265cellular macromolecule catabolic process0.00284126494223344
GO:0044262cellular carbohydrate metabolic process0.00329753507447477
GO:0006066alcohol metabolic process0.00331374989964021
GO:0016406carnitine O-acyltransferase activity0.00368007399453356
GO:0009057macromolecule catabolic process0.00403332330099428
GO:0005975carbohydrate metabolic process0.00546562014632149
GO:0044248cellular catabolic process0.00725663534467636
GO:0009056catabolic process0.0115500949709336
GO:0016620oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor0.0147945239064525
GO:0008374O-acyltransferase activity0.0148097630336227
GO:0005737cytoplasm0.0157018038464137
GO:0016491oxidoreductase activity0.0206757213662636
GO:0016407acetyltransferase activity0.0255988472166892
GO:0043231intracellular membrane-bound organelle0.0260679889230526
GO:0043227membrane-bound organelle0.0260679889230526
GO:0042579microbody0.0352708844022384
GO:0005777peroxisome0.0352708844022384
GO:0043229intracellular organelle0.0385290791314264
GO:0043226organelle0.0385290791314264
GO:0019842vitamin binding0.038950713132341
GO:0050662coenzyme binding0.041968713804469



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
primary circulatory organ4.67e-0818
heart4.67e-0818
primitive heart tube4.67e-0818
primary heart field4.67e-0818
anterior lateral plate mesoderm4.67e-0818
heart tube4.67e-0818
heart primordium4.67e-0818
cardiac mesoderm4.67e-0818
cardiogenic plate4.67e-0818
heart rudiment4.67e-0818
cardiovascular system6.38e-0723
circulatory system6.38e-0723


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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