MCL coexpression mm9:1051

Phase1 CAGE Peaks

	Short description
Mm9::chr11:100002942..100002960,-	p@chr11:100002942..100002960 -
Mm9::chr11:100007232..100007249,-	p1@Krt19
Mm9::chr13:59777115..59777175,-	p1@Golm1
Mm9::chr18:46633725..46633726,+	p@chr18:46633725..46633726 +
Mm9::chr18:81584437..81584438,+	p@chr18:81584437..81584438 +
Mm9::chr2:132771471..132771487,-	p8@Fermt1
Mm9::chr2:132771660..132771670,-	p11@Fermt1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0042383	sarcolemma	0.0420843071629665
GO:0030018	Z disc	0.0420843071629665
GO:0031674	I band	0.0420843071629665
GO:0030017	sarcomere	0.0420843071629665
GO:0044449	contractile fiber part	0.0420843071629665
GO:0030016	myofibril	0.0420843071629665
GO:0043292	contractile fiber	0.0420843071629665
GO:0005200	structural constituent of cytoskeleton	0.0420843071629665
GO:0005882	intermediate filament	0.046250788779941
GO:0045111	intermediate filament cytoskeleton	0.046250788779941

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
endo-epithelial cell	1.96e-12	15
intestinal epithelial cell	3.64e-12	9
epithelial cell of alimentary canal	3.64e-12	9
epithelial cell	1.16e-11	25
endodermal cell	6.81e-10	20
brush border epithelial cell	5.86e-09	6
gut absorptive cell	5.86e-09	6
absorptive cell	5.86e-09	6
enterocyte	5.86e-09	6
columnar/cuboidal epithelial cell	1.66e-07	7

Uber Anatomy

Ontology term	p-value	n
gastrointestinal system	5.81e-34	47
intestine	1.41e-31	31
mucosa	4.60e-20	15
intestinal mucosa	2.99e-17	13
anatomical wall	2.99e-17	13
wall of intestine	2.99e-17	13
gastrointestinal system mucosa	2.99e-17	13
digestive system	1.73e-14	116
digestive tract	1.73e-14	116
primitive gut	1.73e-14	116
endoderm-derived structure	5.14e-14	118
endoderm	5.14e-14	118
presumptive endoderm	5.14e-14	118
subdivision of digestive tract	7.58e-13	114
epithelium of mucosa	3.64e-12	9
gastrointestinal system epithelium	3.64e-12	9
intestinal epithelium	3.64e-12	9
organ component layer	9.49e-11	24
simple columnar epithelium	1.61e-09	11

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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