MCL coexpression mm9:1418
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr19:34953822..34953888,- | p3@Pank1 |
| Mm9::chr1:166829711..166829727,- | p@chr1:166829711..166829727 - |
| Mm9::chr1:189432857..189432870,+ | p7@Esrrg |
| Mm9::chr1:189432881..189432903,+ | p2@Esrrg |
| Mm9::chr1:189432907..189432926,+ | p3@Esrrg |
| Mm9::chr4:120488308..120488366,- | p1@Nfyc |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0050682 | AF-2 domain binding | 0.00437322249490112 |
| GO:0045893 | positive regulation of transcription, DNA-dependent | 0.00437322249490112 |
| GO:0045941 | positive regulation of transcription | 0.00437322249490112 |
| GO:0045935 | positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.00437322249490112 |
| GO:0031325 | positive regulation of cellular metabolic process | 0.00479707233637392 |
| GO:0009893 | positive regulation of metabolic process | 0.00479707233637392 |
| GO:0043565 | sequence-specific DNA binding | 0.00556400150565914 |
| GO:0016439 | tRNA-pseudouridine synthase activity | 0.012219825711145 |
| GO:0048522 | positive regulation of cellular process | 0.012219825711145 |
| GO:0003700 | transcription factor activity | 0.012219825711145 |
| GO:0009982 | pseudouridine synthase activity | 0.012219825711145 |
| GO:0048518 | positive regulation of biological process | 0.012219825711145 |
| GO:0016866 | intramolecular transferase activity | 0.0173410538729427 |
| GO:0005496 | steroid binding | 0.0260841264964928 |
| GO:0019904 | protein domain specific binding | 0.0274485626190369 |
| GO:0006355 | regulation of transcription, DNA-dependent | 0.035536894862443 |
| GO:0006351 | transcription, DNA-dependent | 0.035536894862443 |
| GO:0032774 | RNA biosynthetic process | 0.035536894862443 |
| GO:0003677 | DNA binding | 0.035536894862443 |
| GO:0045449 | regulation of transcription | 0.035536894862443 |
| GO:0019219 | regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.035536894862443 |
| GO:0006350 | transcription | 0.035536894862443 |
| GO:0005516 | calmodulin binding | 0.035536894862443 |
| GO:0010468 | regulation of gene expression | 0.035536894862443 |
| GO:0031323 | regulation of cellular metabolic process | 0.0369695037747075 |
| GO:0019222 | regulation of metabolic process | 0.0382249283767296 |
| GO:0016070 | RNA metabolic process | 0.0387779922786696 |
| GO:0016853 | isomerase activity | 0.0420571120835355 |
| GO:0016563 | transcription activator activity | 0.047518768087866 |
| GO:0010467 | gene expression | 0.049980793853034 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| compound organ | 2.05e-09 | 43 |
| primary circulatory organ | 1.15e-08 | 18 |
| heart | 1.15e-08 | 18 |
| primitive heart tube | 1.15e-08 | 18 |
| primary heart field | 1.15e-08 | 18 |
| anterior lateral plate mesoderm | 1.15e-08 | 18 |
| heart tube | 1.15e-08 | 18 |
| heart primordium | 1.15e-08 | 18 |
| cardiac mesoderm | 1.15e-08 | 18 |
| cardiogenic plate | 1.15e-08 | 18 |
| heart rudiment | 1.15e-08 | 18 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.135108 |
| MA0004.1 | 0.536396 |
| MA0006.1 | 0.359699 |
| MA0007.1 | 0.52077 |
| MA0009.1 | 0.987341 |
| MA0014.1 | 0.0315641 |
| MA0017.1 | 0.387481 |
| MA0019.1 | 0.800946 |
| MA0024.1 | 0.942716 |
| MA0025.1 | 1.22395 |
| MA0027.1 | 2.64231 |
| MA0028.1 | 0.370592 |
| MA0029.1 | 0.920529 |
| MA0030.1 | 0.927235 |
| MA0031.1 | 0.890871 |
| MA0038.1 | 0.686534 |
| MA0040.1 | 1.00009 |
| MA0041.1 | 0.457338 |
| MA0042.1 | 0.443591 |
| MA0043.1 | 1.08567 |
| MA0046.1 | 1.02391 |
| MA0048.1 | 0.486223 |
| MA0050.1 | 0.57678 |
| MA0051.1 | 0.695779 |
| MA0052.1 | 5.36027 |
| MA0055.1 | 0.0585191 |
| MA0056.1 | 0 |
| MA0057.1 | 0.457693 |
| MA0058.1 | 0.436487 |
| MA0059.1 | 1.14076 |
| MA0060.1 | 0.757042 |
| MA0061.1 | 0.307097 |
| MA0063.1 | 0 |
| MA0066.1 | 0.675169 |
| MA0067.1 | 1.33603 |
| MA0068.1 | 2.09737 |
| MA0069.1 | 1.00864 |
| MA0070.1 | 0.998765 |
| MA0071.1 | 1.41046 |
| MA0072.1 | 0.990133 |
| MA0073.1 | 5.00847 |
| MA0074.1 | 1.54084 |
| MA0076.1 | 0.407465 |
| MA0077.1 | 0.968053 |
| MA0078.1 | 0.729877 |
| MA0081.1 | 2.07288 |
| MA0083.1 | 1.08487 |
| MA0084.1 | 1.66561 |
| MA0087.1 | 1.04109 |
| MA0088.1 | 0.358337 |
| MA0089.1 | 0 |
| MA0090.1 | 2.16326 |
| MA0091.1 | 1.3559 |
| MA0092.1 | 0.501022 |
| MA0093.1 | 0.379257 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.626021 |
| MA0101.1 | 0.458688 |
| MA0103.1 | 0.398766 |
| MA0105.1 | 0.199622 |
| MA0106.1 | 0.737893 |
| MA0107.1 | 0.392331 |
| MA0108.2 | 1.92698 |
| MA0109.1 | 0 |
| MA0111.1 | 0.515457 |
| MA0113.1 | 0.708789 |
| MA0114.1 | 0.304661 |
| MA0115.1 | 1.08851 |
| MA0116.1 | 0.359483 |
| MA0117.1 | 1.05576 |
| MA0119.1 | 0.459301 |
| MA0122.1 | 1.07591 |
| MA0124.1 | 1.28237 |
| MA0125.1 | 1.20757 |
| MA0130.1 | 0 |
| MA0131.1 | 0.796279 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.1226 |
| MA0136.1 | 0.658622 |
| MA0139.1 | 0.243463 |
| MA0140.1 | 0.625902 |
| MA0141.1 | 1.07584 |
| MA0142.1 | 0.876028 |
| MA0143.1 | 0.725672 |
| MA0144.1 | 0.829535 |
| MA0145.1 | 0.379391 |
| MA0146.1 | 0.153598 |
| MA0147.1 | 0.320675 |
| MA0148.1 | 0.553294 |
| MA0149.1 | 0.464445 |
| MA0062.2 | 0.204999 |
| MA0035.2 | 0.630778 |
| MA0039.2 | 0.769467 |
| MA0138.2 | 0.788113 |
| MA0002.2 | 0.246463 |
| MA0137.2 | 0.416331 |
| MA0104.2 | 0.261255 |
| MA0047.2 | 0.685741 |
| MA0112.2 | 0.119197 |
| MA0065.2 | 1.24784 |
| MA0150.1 | 0.520653 |
| MA0151.1 | 0 |
| MA0152.1 | 0.685852 |
| MA0153.1 | 1.13945 |
| MA0154.1 | 0.480757 |
| MA0155.1 | 1.33283 |
| MA0156.1 | 0.406559 |
| MA0157.1 | 0.843181 |
| MA0158.1 | 0 |
| MA0159.1 | 0.331229 |
| MA0160.1 | 0.556423 |
| MA0161.1 | 0 |
| MA0162.1 | 1.08528 |
| MA0163.1 | 0.372305 |
| MA0164.1 | 0.658997 |
| MA0080.2 | 0.393257 |
| MA0018.2 | 0.669032 |
| MA0099.2 | 1.83891 |
| MA0079.2 | 0.730639 |
| MA0102.2 | 1.7182 |
| MA0258.1 | 0.290587 |
| MA0259.1 | 0.309517 |
| MA0442.1 | 0 |
