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MCL coexpression mm9:700

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:113427054..113427106,-p1@Slc39a11
Mm9::chr11:5420973..5420992,+p1@Xbp1
Mm9::chr11:84683690..84683732,-p4@Ggnbp2
Mm9::chr12:70285164..70285205,+p1@Mgat2
Mm9::chr15:88906488..88906535,+p1@Trabd
Mm9::chr17:74738503..74738558,+p@chr17:74738503..74738558
+
Mm9::chr5:31262609..31262693,-p1@Preb
Mm9::chr5:31262699..31262712,-p2@Preb
Mm9::chr6:108778627..108778715,+p1@Edem1
Mm9::chr8:72826660..72826703,+p1@Cope


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005783endoplasmic reticulum0.0226217276537667
GO:0046462monoacylglycerol metabolic process0.0380066257364183
GO:0006890retrograde vesicle-mediated transport, Golgi to ER0.0380066257364183
GO:00038462-acylglycerol O-acyltransferase activity0.0380066257364183
GO:0019432triacylglycerol biosynthetic process0.0380066257364183
GO:0006651diacylglycerol biosynthetic process0.0380066257364183
GO:0030433ER-associated protein catabolic process0.0380066257364183
GO:0004571mannosyl-oligosaccharide 1,2-alpha-mannosidase activity0.0380066257364183
GO:0006515misfolded or incompletely synthesized protein catabolic process0.0380066257364183
GO:0043231intracellular membrane-bound organelle0.0380066257364183
GO:0043227membrane-bound organelle0.0380066257364183
GO:0015924mannosyl-oligosaccharide mannosidase activity0.0380066257364183
GO:0046460neutral lipid biosynthetic process0.0380066257364183
GO:0046463acylglycerol biosynthetic process0.0380066257364183
GO:0046504glycerol ether biosynthetic process0.0380066257364183
GO:0045017glycerolipid biosynthetic process0.0380066257364183
GO:0046339diacylglycerol metabolic process0.0380066257364183
GO:0050892intestinal absorption0.0380066257364183
GO:0030126COPI vesicle coat0.0380066257364183
GO:0030663COPI coated vesicle membrane0.0380066257364183
GO:0044444cytoplasmic part0.042213393607381
GO:0030137COPI-coated vesicle0.042213393607381
GO:0043161proteasomal ubiquitin-dependent protein catabolic process0.0429068815323417
GO:0022600digestive system process0.0429068815323417
GO:0016411acylglycerol O-acyltransferase activity0.0429068815323417
GO:0015923mannosidase activity0.0429068815323417
GO:0031410cytoplasmic vesicle0.0429068815323417
GO:0043229intracellular organelle0.0429068815323417
GO:0012505endomembrane system0.0429068815323417
GO:0043226organelle0.0429068815323417
GO:0031982vesicle0.0431141534842245
GO:0006641triacylglycerol metabolic process0.0481607130753447
GO:0006071glycerol metabolic process0.0481607130753447
GO:0019751polyol metabolic process0.0481607130753447
GO:0030176integral to endoplasmic reticulum membrane0.0481607130753447
GO:0006829zinc ion transport0.0497453160918431
GO:0005737cytoplasm0.0497453160918431
GO:0031227intrinsic to endoplasmic reticulum membrane0.0497453160918431
GO:0030120vesicle coat0.0497453160918431
GO:0006639acylglycerol metabolic process0.0497453160918431
GO:0046486glycerolipid metabolic process0.0497453160918431
GO:0006638neutral lipid metabolic process0.0497453160918431
GO:0030662coated vesicle membrane0.0497453160918431
GO:0006662glycerol ether metabolic process0.0497453160918431



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
epithelial cell1.82e-0725
endodermal cell8.29e-0720

Uber Anatomy
Ontology termp-valuen
endoderm-derived structure3.89e-12118
endoderm3.89e-12118
presumptive endoderm3.89e-12118
digestive system1.72e-11116
digestive tract1.72e-11116
primitive gut1.72e-11116
subdivision of digestive tract9.66e-11114
gastrointestinal system3.93e-1047
intestine4.30e-1031
trunk mesenchyme2.50e-0945
trunk2.84e-0990
mucosa4.39e-0815
exocrine gland1.70e-0725
exocrine system1.70e-0725
intestinal mucosa3.03e-0713
anatomical wall3.03e-0713
wall of intestine3.03e-0713
gastrointestinal system mucosa3.03e-0713
organ component layer4.40e-0724
pancreas5.80e-0712
mesenchyme6.08e-0761
entire embryonic mesenchyme6.08e-0761
unilaminar epithelium7.38e-0766


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.14.42901
MA0004.10.360508
MA0006.11.13936
MA0007.10.346734
MA0009.10.780842
MA0014.14.20731
MA0017.10.233089
MA0019.10.603066
MA0024.10.737933
MA0025.11.01089
MA0027.12.42079
MA0028.11.83149
MA0029.10.716673
MA0030.10.723093
MA0031.10.688336
MA0038.11.24163
MA0040.10.79313
MA0041.10.291712
MA0042.10.279998
MA0043.10.875991
MA0046.10.816137
MA0048.10.236433
MA0050.10.396459
MA0051.10.504875
MA0052.10.801048
MA0055.10.0660514
MA0056.10
MA0057.10.216209
MA0058.10.752621
MA0059.10.28489
MA0060.14.29114
MA0061.12.21331
MA0063.10
MA0066.10.485868
MA0067.11.12095
MA0068.10.0621035
MA0069.10.801381
MA0070.10.791856
MA0071.10.395679
MA0072.10.783532
MA0073.111.2333
MA0074.10.451832
MA0076.10.696577
MA0077.10.762273
MA0078.10.536502
MA0081.10.305576
MA0083.10.875209
MA0084.11.44691
MA0087.10.832758
MA0088.10.623059
MA0089.10
MA0090.10.329158
MA0091.10.372635
MA0092.10.329444
MA0093.10.642324
MA0095.10
MA0098.10
MA0100.10.440912
MA0101.10.292867
MA0103.10.242398
MA0105.10.632131
MA0106.10.543967
MA0107.10.66744
MA0108.20.625209
MA0109.10
MA0111.10.342068
MA0113.10.516916
MA0114.10.167085
MA0115.10.878749
MA0116.11.13868
MA0117.11.97331
MA0119.10.293392
MA0122.10.866511
MA0124.11.06819
MA0125.10.994853
MA0130.10
MA0131.10.598671
MA0132.10
MA0133.10
MA0135.10.911905
MA0136.10.470672
MA0139.10.385513
MA0140.11.12231
MA0141.10.259554
MA0142.10.674191
MA0143.10.53259
MA0144.10.506239
MA0145.10.664015
MA0146.13.4805
MA0147.11.6106
MA0148.10.375491
MA0149.10.2978
MA0062.21.08157
MA0035.20.44524
MA0039.25.3709
MA0138.20.590987
MA0002.20.123715
MA0137.20.713675
MA0104.22.61375
MA0047.20.495607
MA0112.20.371983
MA0065.20.163769
MA0150.10.346631
MA0151.10
MA0152.10.495709
MA0153.10.92832
MA0154.10.501928
MA0155.10.732931
MA0156.10.694831
MA0157.10.642984
MA0158.10
MA0159.11.05
MA0160.10.378276
MA0161.10
MA0162.12.22848
MA0163.11.69351
MA0164.10.471016
MA0080.20.237846
MA0018.20.480226
MA0099.20.584892
MA0079.25.69901
MA0102.21.49914
MA0258.10.156336
MA0259.10.981631
MA0442.10
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