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MCL coexpression mm9:772

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:100939677..100939722,+p1@Hsd17b1
Mm9::chr11:100939727..100939736,+p3@Hsd17b1
Mm9::chr11:100939737..100939749,+p2@Hsd17b1
Mm9::chr11:100939751..100939760,+p4@Hsd17b1
Mm9::chr14:121173828..121173831,-p@chr14:121173828..121173831
-
Mm9::chr14:24786370..24786382,-p@chr14:24786370..24786382
-
Mm9::chr1:75503742..75503759,+p2@Inha
Mm9::chr1:75503989..75504030,+p@chr1:75503989..75504030
+
Mm9::chr8:67099288..67099296,-p@chr8:67099288..67099296
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0006703estrogen biosynthetic process0.00635459742497994
GO:0008210estrogen metabolic process0.00635459742497994
GO:0004303estradiol 17-beta-dehydrogenase activity0.00847186806642716
GO:0016229steroid dehydrogenase activity0.0166730493051983
GO:0042446hormone biosynthetic process0.0228564951253319
GO:0006694steroid biosynthetic process0.0364738676396612
GO:0042445hormone metabolic process0.0366883263182712
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor0.0376907310028946
GO:0005179hormone activity0.0376907310028946
GO:0016614oxidoreductase activity, acting on CH-OH group of donors0.0376907310028946
GO:0008202steroid metabolic process0.0392947383329716
GO:0008083growth factor activity0.0392947383329716



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
external genitalia1.25e-4217
indifferent external genitalia1.25e-4217
indifferent gonad1.25e-4217
testis7.67e-4214
gonad3.14e-4018
gonad primordium3.14e-4018
male reproductive organ5.08e-3915
male organism1.50e-3616
male reproductive system1.50e-3616
reproductive organ5.11e-3024
reproductive structure1.17e-2726
reproductive system1.17e-2726
body cavity3.19e-1937
body cavity or lining3.19e-1937
body cavity precursor1.07e-1838
anatomical cavity3.38e-1839
anatomical space3.44e-1257
immaterial anatomical entity1.54e-0879


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0343274
MA0004.10.394951
MA0006.10.238555
MA0007.10.38073
MA0009.10.82278
MA0014.10.00813637
MA0017.10.726051
MA0019.10.642876
MA0024.10.779446
MA0025.11.05446
MA0027.12.46647
MA0028.10.24786
MA0029.10.757957
MA0030.10.764448
MA0031.10.729293
MA0038.10.534262
MA0040.10.835181
MA0041.10.323687
MA0042.10.311486
MA0043.10.918718
MA0046.10.858391
MA0048.10.0824771
MA0050.10.431976
MA0051.10.542972
MA0052.10.84317
MA0055.10.221677
MA0056.10
MA0057.10.549903
MA0058.10.305206
MA0059.10.316585
MA0060.10.169058
MA0061.10.194456
MA0063.10
MA0066.10.523573
MA0067.11.16502
MA0068.10.266547
MA0069.10.843506
MA0070.11.94648
MA0071.10.431174
MA0072.10.825495
MA0073.11.23161
MA0074.10.488775
MA0076.10.279739
MA0077.10.804033
MA0078.10.575205
MA0081.10.338098
MA0083.12.11865
MA0084.11.49188
MA0087.10.87515
MA0088.10.0492918
MA0089.10
MA0090.10.362551
MA0091.10.407455
MA0092.10.362847
MA0093.10.2553
MA0095.10
MA0098.10
MA0100.10.477594
MA0101.10.324888
MA0103.10.272167
MA0105.10.35523
MA0106.10.582805
MA0107.10.73569
MA0108.20.665343
MA0109.10
MA0111.10.375908
MA0113.10.555251
MA0114.11.06861
MA0115.10.921497
MA0116.11.93347
MA0117.10.88947
MA0119.10.325434
MA0122.10.909168
MA0124.11.11203
MA0125.11.03833
MA0130.10
MA0131.10.638414
MA0132.10
MA0133.10
MA0135.10.954884
MA0136.10.508047
MA0139.10.143341
MA0140.10.477483
MA0141.11.43798
MA0142.10.714976
MA0143.10.571221
MA0144.10.195095
MA0145.10.77191
MA0146.10.0111657
MA0147.10.205697
MA0148.10.410398
MA0149.10.330018
MA0062.20.113962
MA0035.21.21101
MA0039.20.288731
MA0138.20.630612
MA0002.22.7265
MA0137.20.783415
MA0104.20.157347
MA0047.20.533516
MA0112.20.0543294
MA0065.21.65733
MA0150.10.380623
MA0151.10
MA0152.10.53362
MA0153.10.971406
MA0154.10.982083
MA0155.10.0631765
MA0156.10.278949
MA0157.10.683365
MA0158.10
MA0159.10.214506
MA0160.10.413266
MA0161.10
MA0162.10.0143037
MA0163.10.0124565
MA0164.10.508398
MA0080.20.267388
MA0018.20.51781
MA0099.20.624421
MA0079.20.0340753
MA0102.21.5442
MA0258.10.180934
MA0259.10.196451
MA0442.10