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MCL coexpression mm9:1192

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Phase1 CAGE Peaks

 Short description
Mm9::chr3:107815477..107815490,-p@chr3:107815477..107815490
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Mm9::chr3:107847603..107847656,-p2@Gstm4
Mm9::chr3:97432767..97432787,+p1@Fmo5
Mm9::chr3:97455674..97455688,+p@chr3:97455674..97455688
+
Mm9::chr3:97455708..97455720,+p@chr3:97455708..97455720
+
Mm9::chr3:97455776..97455788,+p@chr3:97455776..97455788
+
Mm9::chr5:117083024..117083028,-p@chr5:117083024..117083028
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0042537benzene and derivative metabolic process0.00208184955897661
GO:0042178xenobiotic catabolic process0.00208184955897661
GO:0018916nitrobenzene metabolic process0.00208184955897661
GO:0004499flavin-containing monooxygenase activity0.00780608038529814
GO:0050661NADP binding0.0124866489573661
GO:0006805xenobiotic metabolic process0.0124866489573661
GO:0009410response to xenobiotic stimulus0.0124866489573661
GO:0043449alkene metabolic process0.0130510042663577
GO:0016709oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen0.0130510042663577
GO:0031227intrinsic to endoplasmic reticulum membrane0.0130510042663577
GO:0004364glutathione transferase activity0.0130510042663577
GO:0016765transferase activity, transferring alkyl or aryl (other than methyl) groups0.0262787067516743
GO:0031300intrinsic to organelle membrane0.0262787067516743
GO:0050660FAD binding0.0262787067516743
GO:0005789endoplasmic reticulum membrane0.0284391120597181
GO:0042175nuclear envelope-endoplasmic reticulum network0.0284391120597181
GO:0044432endoplasmic reticulum part0.0293272112718888
GO:0006725aromatic compound metabolic process0.037049602663685
GO:0050662coenzyme binding0.037049602663685
GO:0004497monooxygenase activity0.037049602663685
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen0.037049602663685
GO:0005792microsome0.0424504675122203
GO:0042598vesicular fraction0.0424504675122203
GO:0048037cofactor binding0.0435188339884722



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
endoderm-derived structure4.04e-16118
endoderm4.04e-16118
presumptive endoderm4.04e-16118
digestive system4.09e-16116
digestive tract4.09e-16116
primitive gut4.09e-16116
liver6.99e-1522
epithelial sac6.99e-1522
digestive gland6.99e-1522
epithelium of foregut-midgut junction6.99e-1522
anatomical boundary6.99e-1522
hepatobiliary system6.99e-1522
foregut-midgut junction6.99e-1522
hepatic diverticulum6.99e-1522
liver primordium6.99e-1522
septum transversum6.99e-1522
liver bud6.99e-1522
subdivision of digestive tract8.72e-15114
digestive tract diverticulum6.94e-1423
sac6.94e-1423
intestine3.50e-1231
exocrine gland3.82e-1225
exocrine system3.82e-1225
gastrointestinal system1.60e-1147
trunk mesenchyme4.68e-1145
abdomen element6.37e-1049
abdominal segment element6.37e-1049
abdominal segment of trunk6.37e-1049
abdomen6.37e-1049
mesenchyme9.07e-0961
entire embryonic mesenchyme9.07e-0961
subdivision of trunk6.06e-0866
epithelial tube6.81e-0847
trunk region element5.86e-0779


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0286946
MA0004.10.481116
MA0006.10.837454
MA0007.10.465969
MA0009.10.92425
MA0014.10.222567
MA0017.10.337808
MA0019.10.740036
MA0024.10.880057
MA0025.11.15921
MA0027.12.57545
MA0028.11.55156
MA0029.10.858105
MA0030.10.864739
MA0031.10.828781
MA0038.10.62758
MA0040.10.936879
MA0041.10.404721
MA0042.10.391504
MA0043.11.02178
MA0046.10.960497
MA0048.10.128106
MA0050.10.520357
MA0051.10.636645
MA0052.12.17396
MA0055.10.0406078
MA0056.10
MA0057.10.117936
MA0058.10.384683
MA0059.10.397033
MA0060.10.232592
MA0061.10.261749
MA0063.10
MA0066.10.616444
MA0067.11.27078
MA0068.10.385183
MA0069.10.945354
MA0070.10.93557
MA0071.11.29103
MA0072.10.927016
MA0073.10.0004304
MA0074.10.580087
MA0076.10.356883
MA0077.10.905143
MA0078.10.670113
MA0081.10.420276
MA0083.11.02098
MA0084.11.59945
MA0087.10.977537
MA0088.10.0841779
MA0089.10
MA0090.11.1347
MA0091.10.494398
MA0092.10.446857
MA0093.10.329976
MA0095.10
MA0098.10
MA0100.10.568369
MA0101.10.406019
MA0103.10.348572
MA0105.10.162418
MA0106.10.677988
MA0107.10.342432
MA0108.20.763162
MA0109.10
MA0111.10.460823
MA0113.11.56464
MA0114.10.259463
MA0115.11.0246
MA0116.10.836994
MA0117.10.992087
MA0119.10.40661
MA0122.11.01209
MA0124.11.21735
MA0125.11.14291
MA0130.10
MA0131.10.735438
MA0132.10
MA0133.10
MA0135.11.05845
MA0136.10.600242
MA0139.10.202522
MA0140.10.568252
MA0141.10.368264
MA0142.10.814115
MA0143.10.665982
MA0144.10.262477
MA0145.10.304732
MA0146.10.0256827
MA0147.10.274511
MA0148.10.49752
MA0149.10.411562
MA0062.20.167299
MA0035.20.573016
MA0039.20.113749
MA0138.20.727395
MA0002.20.205289
MA0137.20.365364
MA0104.20.218974
MA0047.20.626803
MA0112.21.05549
MA0065.20.305574
MA0150.10.465855
MA0151.10
MA0152.10.626912
MA0153.11.07519
MA0154.10.126143
MA0155.10.687925
MA0156.10.936991
MA0157.10.781683
MA0158.10
MA0159.10.284457
MA0160.10.50056
MA0161.10
MA0162.10.127623
MA0163.10.519779
MA0164.10.600609
MA0080.20.908823
MA0018.20.610433
MA0099.20.721008
MA0079.20.000323799
MA0102.21.65195
MA0258.10.688848
MA0259.10.26402
MA0442.10
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