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UBERON:0000080

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Name:mesonephros
Namespace:FANTOM
Definition:"In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney[GO]. One of three excretory organs that develop in vertebrates. It serves as the main excretory organ of aquatic vertebrates and as a temporary kidney in higher vertebrates. composed of the mesonephric duct (also called the Wolffian duct), mesonephric tubules, and associated capillary tufts. A single tubule and its associated capillary tuft is called a mesonephric excretory unit; these units are similar in structure and function to nephrons of the adult kidney. The mesonephros is derived from intermediate mesoderm in the vertebrate embryo." [GO:0001823, Wikipedia:Mesonephros]
Xrefs:
links:

AAO:0010384
BTO:0001542
EFO:0000928
EHDAA2:0001130
EHDAA:1581
EHDAA:5903
EMAPA:16744
EMAPA:17369
EMAPA:27644
FMA:72171
GAID:1308
[ Gray986.png Gray986.png]
[ 200px-Gray986.png 200px-Gray986.png]
MESH:A.16.254.500
ncithesaurus:Mesonephros
SCTID:308799002
TAO:0000529
VHOG:0000038
XAO:0000141

ZFA:0000529
Synonyms: "mesonephric kidney" EXACT [XAO:0000141]
"mesonephroi" EXACT PLURAL [1]
"opisthonephros" RELATED [VHOG:0000038, XAO:0000141]
"opisto nephros" RELATED []
"opistonephros" RELATED [2]
"Wolffian body" EXACT [BTO:0001542, GOC:yaf, MESH:A.16.254.500, Wikipedia:Mesonephros]
Comments:By contrast to the pronephros, the histological features of the mesonephros, with its primitive glomeruli, suggest that it probably functions as a primitive kidney, and is involved in the production of much of the amniotic fluid. Within the two mesonephroi, one located on either side of the dorsal mesentery of the hindgut, a substantial number (in the region of about 40 or more) of cranio-caudally segmented mesonephric tubules are formed. It has, however, been suggested that only the most rostrally located 4-6 pairs of mesonephric tubules drain into the mesonephric portion of the nephric duct. This is now seen to extend along the length of the mesonephroi, being located towards their lateral sides. The mesonephros is also retained over a considerably longer period than the pronephros, but gradually undergoes regression in a cranio-caudal direction. While the rostral part displays clear evidence of regression its more caudal part appears to display evidence of functional activity. Within the medial part of the mesonephros, vesicles are formed, although no glomeruli are formed there in this species. It is, however, difficult to believe that the relatively enormous mesonephroi do not have an excretory role in the mouse, only serving as a base for gonadal differentiation. In the human embryo, the medial part of the mesonephric tubules enlarges, become invaginated by capillaries, and form glomeruli. These then take on an excretory role. In the mouse, the mesonephric ducts appear to be patent throughout their length[GUDMAP] comment: Taxon notes: The mesonephros persists and form the permanent kidneys in fishes and amphibians, but in reptiles, birds, and mammals, it atrophies and for the most part disappears rapidly as the permanent kidney (metanephros) begins to develop during the sixth or seventh week. By the beginning of the fifth month only the ducts and a few of the tubules of the mesonephros remain[WP]
Subset: organ_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0002113(kidney),UBERON:0004120(mesoderm-derived structure)
develops_from:UBERON:0002120(pronephros)



Children

derives from:FF:0200027 (mouse (pre) hematopoietic stem cell,aorta-gonad-mesonephros (AGM) region derived sample)
develops from:UBERON:0000998 (seminal vesicle)
part of:UBERON:0000083 (mesonephric tubule),UBERON:0003074 (mesonephric duct),UBERON:0005103 (mesonephric epithelium)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Mouse (Mus musculus)

  • 11948-126B4 (Pre-hematopoietic stem cell, aorta-gonad-mesonephros (AGM) region derived, embryo E9.5)
  • 11951-126B7 (hematopoietic stem cell,aorta-gonad-mesonephros (AGM) region derived, embryo E11.5)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000080 (mesonephros), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
2.83e-65FFCP PHASE2:Mm9::chr18:44264202..44264213,+#_863ba861a61039ca86f24ef51ec8b37fp4@Spink12
2.83e-65FFCP PHASE1:Mm9::chr18:44264202..44264213,+#_863ba861a61039ca86f24ef51ec8b37fp4@Spink12
2.83e-65FFCP PHASE2:Mm9::chr14:63665679..63665688,+#_863ba861a61039ca86f24ef51ec8b37fp4@Defb42
2.83e-65FFCP PHASE1:Mm9::chr10:127470655..127470664,+#_863ba861a61039ca86f24ef51ec8b37fp@chr10:127470655..127470664, +
2.83e-65FFCP PHASE2:Mm9::chr14:63585028..63585037,-#_863ba861a61039ca86f24ef51ec8b37fp@chr14:63585028..63585037, -
2.83e-65FFCP PHASE1:Mm9::chr14:63585028..63585037,-#_863ba861a61039ca86f24ef51ec8b37fp@chr14:63585028..63585037, -
2.83e-65FFCP PHASE1:Mm9::chr14:63665679..63665688,+#_863ba861a61039ca86f24ef51ec8b37fp4@Defb42
2.83e-65FFCP PHASE2:Mm9::chr10:127470655..127470664,+#_863ba861a61039ca86f24ef51ec8b37fp@chr10:127470655..127470664, +
3.99e-50FFCP PHASE2:Mm9::chr2:152388713..152388729,+#_6d594b20498285aa6159a0fefea32780p@chr2:152388713..152388729, +
3.99e-50FFCP PHASE1:Mm9::chr2:152388713..152388729,+#_6d594b20498285aa6159a0fefea32780p@chr2:152388713..152388729, +
5.6e-50FFCP PHASE2:Hg19::chr2:120409486..120409492,+#_cabcc286c3463572d9f2cd678d95bf60p@chr2:120409486..120409492, +
5.6e-50FFCP PHASE1:Hg19::chr2:120409486..120409492,+#_cabcc286c3463572d9f2cd678d95bf60p@chr2:120409486..120409492, +
1.6e-49FFCP PHASE2:Mm9::chr11:105797641..105797656,-#_cc2ab9d92ff022d1f7d27f35fd17814ep4@Cyb561
1.6e-49FFCP PHASE2:Mm9::chr14:63585020..63585025,-#_cc2ab9d92ff022d1f7d27f35fd17814ep@chr14:63585020..63585025, -
1.6e-49FFCP PHASE1:Mm9::chr14:63585020..63585025,-#_cc2ab9d92ff022d1f7d27f35fd17814ep@chr14:63585020..63585025, -
1.6e-49FFCP PHASE1:Mm9::chr11:105797641..105797656,-#_cc2ab9d92ff022d1f7d27f35fd17814ep4@Cyb561
1.6e-49FFCP PHASE2:Mm9::chr14:63585048..63585062,-#_cc2ab9d92ff022d1f7d27f35fd17814ep@chr14:63585048..63585062, -
1.6e-49FFCP PHASE2:Mm9::chr11:76361451..76361499,+#_cc2ab9d92ff022d1f7d27f35fd17814ep@chr11:76361451..76361499, +
1.6e-49FFCP PHASE2:Mm9::chr9:35597686..35597691,-#_cc2ab9d92ff022d1f7d27f35fd17814ep2@D730048I06Rik, p2@Gm17727
1.6e-49FFCP PHASE1:Mm9::chr14:63585048..63585062,-#_cc2ab9d92ff022d1f7d27f35fd17814ep@chr14:63585048..63585062, -
1.6e-49FFCP PHASE1:Mm9::chr9:35597686..35597691,-#_cc2ab9d92ff022d1f7d27f35fd17814ep2@D730048I06Rik, p2@Gm17727
1.6e-49FFCP PHASE1:Mm9::chr11:76361451..76361499,+#_cc2ab9d92ff022d1f7d27f35fd17814ep@chr11:76361451..76361499, +
2.33e-49FFCP PHASE1:Mm9::chr14:51734043..51734054,+#_47d8b28878b64c8d83bb0bdf952b9dd1p2@Eddm3b
2.33e-49FFCP PHASE2:Mm9::chr14:63627556..63627564,-#_47d8b28878b64c8d83bb0bdf952b9dd1p@chr14:63627556..63627564, -
2.33e-49FFCP PHASE1:Mm9::chr9:26611246..26611253,-#_47d8b28878b64c8d83bb0bdf952b9dd1p@chr9:26611246..26611253, -
2.33e-49FFCP PHASE1:Mm9::chr14:63627556..63627564,-#_47d8b28878b64c8d83bb0bdf952b9dd1p@chr14:63627556..63627564, -
2.33e-49FFCP PHASE2:Mm9::chr9:26611246..26611253,-#_47d8b28878b64c8d83bb0bdf952b9dd1p@chr9:26611246..26611253, -
2.33e-49FFCP PHASE2:Mm9::chr9:26732045..26732085,+#_47d8b28878b64c8d83bb0bdf952b9dd1p@chr9:26732045..26732085, +
2.33e-49FFCP PHASE2:Mm9::chr14:51734043..51734054,+#_47d8b28878b64c8d83bb0bdf952b9dd1p2@Eddm3b
2.33e-49FFCP PHASE1:Mm9::chr9:26732045..26732085,+#_47d8b28878b64c8d83bb0bdf952b9dd1p@chr9:26732045..26732085, +
3.4e-49FFCP PHASE2:Mm9::chr2:69981027..69981032,+#_0a5206391c80523bf8cbd1d5f7cb94a9p@chr2:69981027..69981032, +
3.4e-49FFCP PHASE1:Mm9::chr2:69981027..69981032,+#_0a5206391c80523bf8cbd1d5f7cb94a9p@chr2:69981027..69981032, +
9.75e-45FFCP PHASE1:Hg19::chr14:68644730..68644737,+#_14661aa64037d92e6c26b45bde3c6df8p@chr14:68644730..68644737, +
9.75e-45FFCP PHASE2:Hg19::chr1:172416185..172416189,-#_14661aa64037d92e6c26b45bde3c6df8p@chr1:172416185..172416189, -
9.75e-45FFCP PHASE2:Hg19::chr14:68644730..68644737,+#_14661aa64037d92e6c26b45bde3c6df8p@chr14:68644730..68644737, +
9.75e-45FFCP PHASE1:Hg19::chr10:102505655..102505689,+#_14661aa64037d92e6c26b45bde3c6df8p10@PAX2
9.75e-45FFCP PHASE1:Hg19::chr1:172416185..172416189,-#_14661aa64037d92e6c26b45bde3c6df8p@chr1:172416185..172416189, -
9.75e-45FFCP PHASE2:Hg19::chr10:102505655..102505689,+#_14661aa64037d92e6c26b45bde3c6df8p10@PAX2
4.54e-44FFCP PHASE1:Mm9::chr2:152302813..152302821,+#_88572121cf7329450c9964007baf3d3ep3@Defb20
4.54e-44FFCP PHASE2:Mm9::chrX:75798132..75798152,-#_88572121cf7329450c9964007baf3d3ep@chrX:75798132..75798152, -
4.54e-44FFCP PHASE1:Mm9::chr8:25706249..25706254,+#_88572121cf7329450c9964007baf3d3ep@chr8:25706249..25706254, +
4.54e-44FFCP PHASE2:Mm9::chr12:114385720..114385732,-#_88572121cf7329450c9964007baf3d3ep@chr12:114385720..114385732, -
4.54e-44FFCP PHASE1:Mm9::chr1:90155923..90155932,+#_88572121cf7329450c9964007baf3d3ep@chr1:90155923..90155932, +
4.54e-44FFCP PHASE2:Mm9::chr16:23308115..23308126,+#_88572121cf7329450c9964007baf3d3ep@chr16:23308115..23308126, +
4.54e-44FFCP PHASE1:Mm9::chr9:70761885..70761895,+#_88572121cf7329450c9964007baf3d3ep@chr9:70761885..70761895, +
4.54e-44FFCP PHASE1:Mm9::chr9:26704579..26704582,-#_88572121cf7329450c9964007baf3d3ep@chr9:26704579..26704582, -
4.54e-44FFCP PHASE2:Mm9::chr9:100350777..100350782,+#_88572121cf7329450c9964007baf3d3ep@chr9:100350777..100350782, +
4.54e-44FFCP PHASE1:Mm9::chr14:103837894..103837900,+#_88572121cf7329450c9964007baf3d3ep@chr14:103837894..103837900, +
4.54e-44FFCP PHASE2:Mm9::chr5:120078716..120078763,-#_88572121cf7329450c9964007baf3d3ep@chr5:120078716..120078763, -
4.54e-44FFCP PHASE1:Mm9::chrX:75798157..75798162,-#_88572121cf7329450c9964007baf3d3ep@chrX:75798157..75798162, -
4.54e-44FFCP PHASE2:Mm9::chr11:116901540..116901549,-#_88572121cf7329450c9964007baf3d3ep4@uc007mmw.1
4.54e-44FFCP PHASE1:Mm9::chrX:130496372..130496393,-#_88572121cf7329450c9964007baf3d3ep@chrX:130496372..130496393, -
4.54e-44FFCP PHASE1:Mm9::chr14:51680551..51680555,-#_88572121cf7329450c9964007baf3d3ep@chr14:51680551..51680555, -
4.54e-44FFCP PHASE1:Mm9::chr13:21379107..21379136,+#_88572121cf7329450c9964007baf3d3ep@chr13:21379107..21379136, +
4.54e-44FFCP PHASE1:Mm9::chr10:56515486..56515496,+#_88572121cf7329450c9964007baf3d3ep@chr10:56515486..56515496, +
4.54e-44FFCP PHASE2:Mm9::chr16:28323634..28323657,-#_88572121cf7329450c9964007baf3d3ep@chr16:28323634..28323657, -
4.54e-44FFCP PHASE2:Mm9::chr2:164434346..164434353,-#_88572121cf7329450c9964007baf3d3ep@chr2:164434346..164434353, -
4.54e-44FFCP PHASE1:Mm9::chr5:35930667..35930691,+#_88572121cf7329450c9964007baf3d3ep@chr5:35930667..35930691, +
4.54e-44FFCP PHASE1:Mm9::chr1:89596972..89596981,+#_88572121cf7329450c9964007baf3d3ep@chr1:89596972..89596981, +
4.54e-44FFCP PHASE2:Mm9::chr11:101958844..101958851,-#_88572121cf7329450c9964007baf3d3ep@chr11:101958844..101958851, -
4.54e-44FFCP PHASE2:Mm9::chr2:25349488..25349492,-#_88572121cf7329450c9964007baf3d3ep6@Lcn12
4.54e-44FFCP PHASE1:Mm9::chr16:28323634..28323657,-#_88572121cf7329450c9964007baf3d3ep@chr16:28323634..28323657, -
4.54e-44FFCP PHASE1:Mm9::chr11:105797824..105797838,-#_88572121cf7329450c9964007baf3d3ep13@Cyb561
4.54e-44FFCP PHASE2:Mm9::chrX:103276578..103276585,+#_88572121cf7329450c9964007baf3d3ep@chrX:103276578..103276585, +
4.54e-44FFCP PHASE2:Mm9::chr9:35715997..35716008,+#_88572121cf7329450c9964007baf3d3ep1@9230113P08Rik
4.54e-44FFCP PHASE1:Mm9::chrX:12571679..12571688,-#_88572121cf7329450c9964007baf3d3ep@chrX:12571679..12571688, -
4.54e-44FFCP PHASE2:Mm9::chr9:26785438..26785446,-#_88572121cf7329450c9964007baf3d3ep3@Acad8
4.54e-44FFCP PHASE1:Mm9::chr7:25563187..25563205,+#_88572121cf7329450c9964007baf3d3ep@chr7:25563187..25563205, +
4.54e-44FFCP PHASE2:Mm9::chr11:34107562..34107572,-#_88572121cf7329450c9964007baf3d3ep@chr11:34107562..34107572, -
4.54e-44FFCP PHASE1:Mm9::chr9:35657485..35657490,-#_88572121cf7329450c9964007baf3d3ep3@Gm3428
4.54e-44FFCP PHASE2:Mm9::chr5:31379550..31379559,+#_88572121cf7329450c9964007baf3d3ep@chr5:31379550..31379559, +
4.54e-44FFCP PHASE1:Mm9::chr2:148676919..148676930,-#_88572121cf7329450c9964007baf3d3ep3@9230104L09Rik
4.54e-44FFCP PHASE1:Mm9::chr15:75304900..75304907,+#_88572121cf7329450c9964007baf3d3ep@chr15:75304900..75304907, +
4.54e-44FFCP PHASE2:Mm9::chr13:52712765..52712772,+#_88572121cf7329450c9964007baf3d3ep@chr13:52712765..52712772, +
4.54e-44FFCP PHASE2:Mm9::chr16:43230846..43230884,+#_88572121cf7329450c9964007baf3d3ep@chr16:43230846..43230884, +
4.54e-44FFCP PHASE1:Mm9::chr13:21380610..21380620,-#_88572121cf7329450c9964007baf3d3ep@chr13:21380610..21380620, -
4.54e-44FFCP PHASE2:Mm9::chr3:146278590..146278595,-#_88572121cf7329450c9964007baf3d3ep10@Dnase2b
4.54e-44FFCP PHASE2:Mm9::chr13:21381141..21381155,-#_88572121cf7329450c9964007baf3d3ep@chr13:21381141..21381155, -
4.54e-44FFCP PHASE2:Mm9::chr15:54678983..54678995,-#_88572121cf7329450c9964007baf3d3ep@chr15:54678983..54678995, -
4.54e-44FFCP PHASE2:Mm9::chr14:52542711..52542716,-#_88572121cf7329450c9964007baf3d3ep2@Rnase13
4.54e-44FFCP PHASE2:Mm9::chr1:168436322..168436326,-#_88572121cf7329450c9964007baf3d3ep@chr1:168436322..168436326, -
4.54e-44FFCP PHASE2:Mm9::chr2:152290340..152290344,-#_88572121cf7329450c9964007baf3d3ep2@Defb23
4.54e-44FFCP PHASE1:Mm9::chr11:101959159..101959163,+#_88572121cf7329450c9964007baf3d3ep@chr11:101959159..101959163, +
4.54e-44FFCP PHASE2:Mm9::chr2:75866210..75866235,+#_88572121cf7329450c9964007baf3d3ep@chr2:75866210..75866235, +
4.54e-44FFCP PHASE2:Mm9::chr7:151928014..151928021,+#_88572121cf7329450c9964007baf3d3ep@chr7:151928014..151928021, +
4.54e-44FFCP PHASE1:Mm9::chr4:123977104..123977120,-#_88572121cf7329450c9964007baf3d3ep1@ENSMUST00000139012, p1@uc008uqo.1
4.54e-44FFCP PHASE2:Mm9::chr14:103837894..103837900,+#_88572121cf7329450c9964007baf3d3ep@chr14:103837894..103837900, +
4.54e-44FFCP PHASE1:Mm9::chr14:51627586..51627595,+#_88572121cf7329450c9964007baf3d3ep4@Rnase10
4.54e-44FFCP PHASE1:Mm9::chr13:21378296..21378303,+#_88572121cf7329450c9964007baf3d3ep@chr13:21378296..21378303, +
4.54e-44FFCP PHASE2:Mm9::chr1:90155966..90155989,+#_88572121cf7329450c9964007baf3d3ep@chr1:90155966..90155989, +
4.54e-44FFCP PHASE2:Mm9::chr18:46301295..46301302,-#_88572121cf7329450c9964007baf3d3ep@chr18:46301295..46301302, -
4.54e-44FFCP PHASE2:Mm9::chr13:21379065..21379072,-#_88572121cf7329450c9964007baf3d3ep@chr13:21379065..21379072, -
4.54e-44FFCP PHASE1:Mm9::chr9:35585507..35585517,-#_88572121cf7329450c9964007baf3d3ep4@Gm17727
4.54e-44FFCP PHASE2:Mm9::chr5:31377177..31377184,+#_88572121cf7329450c9964007baf3d3ep@chr5:31377177..31377184, +
4.54e-44FFCP PHASE1:Mm9::chr1:39707572..39707583,+#_88572121cf7329450c9964007baf3d3ep@chr1:39707572..39707583, +
4.54e-44FFCP PHASE1:Mm9::chr15:54678902..54678911,-#_88572121cf7329450c9964007baf3d3ep@chr15:54678902..54678911, -
4.54e-44FFCP PHASE1:Mm9::chr12:103896102..103896116,-#_88572121cf7329450c9964007baf3d3ep@chr12:103896102..103896116, -
4.54e-44FFCP PHASE2:Mm9::chr19:24582739..24582748,-#_88572121cf7329450c9964007baf3d3ep@chr19:24582739..24582748, -
4.54e-44FFCP PHASE2:Mm9::chr11:53938008..53938022,+#_88572121cf7329450c9964007baf3d3ep11@P4ha2
4.54e-44FFCP PHASE2:Mm9::chr7:31507623..31507631,+#_88572121cf7329450c9964007baf3d3ep4@Atp4a










Property "Property value" (as page type) with input value "UBPROP:0000001 "Organ that is the definitive adult kidney. It replaces the earlier pronephros, which degenerates as the mesonephros becomes functional in feeding stage tadpoles.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

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