UBERON:0001043
From FANTOM5_SSTAR
| Name: | esophagus | ||
|---|---|---|---|
| Namespace: | FANTOM | ||
| Definition: | "Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993)." Wikipedia:Esophagus | ||
| Xrefs: |
| ||
| Synonyms: |
"gullet" EXACT [] "oesophagus" EXACT [] "��ｿｽ驛ｽophagus" RELATED LATIN [Wikipedia:Esophagus] | ||
| Comments: | esophagus NOT part of gut in MA. part of gut in ZFA. part_of gut (via UGIT) in FMA. Consider splitting. Interspecies: The human oesophagus is 25 cm long and has a diameter of ca. 2 cm. Only little information was found on the oesophagus in rat, rabbit and pig. The oesophagus of rat (75 x 2 mm) and rabbit has no mucous glands and the cardia of the stomach has a well-developed sphincter, which prevents them from vomiting (Hebel and Stromberg, 1988; Manning et al., 1994). Morphologically the oesophagus is similar in man and pig; both are omnivores and have a non-keratinised epithelium, submucous glands and similar membrane enzymes. Like in humans, pigs can suffer from reflux oesophagitis and stress ulceration of the oesophagus. The pig oesophagus may therefore be a good model for investigation compared to the human oesophagus (Christie et al., 1995) | ||
| Alt_id: | UBERON:FBbt_00005381-FMA_7131-MA_0000352-MIAA_0000048-XAO_0000127-ZFA_0000204 | ||
| Subset: |
major_organ organ_slim uberon_slim vertebrate_core |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0004921(subdivision of digestive tract),UBERON:0005178(thoracic cavity element),UBERON:0013765(digestive system element) |
|---|---|
| develops_from: | UBERON:0001041(foregut) |
| part_of: | UBERON:0004908(upper digestive tract) |
Children
| is a: | FF:0102817 (esophageal cancer cell line) |
|---|---|
| derives from: | FF:0010015 (human esophagus - adult sample) |
| part of: | CL:0002252 (epithelial cell of esophagus),CL:0002599 (smooth muscle cell of the esophagus) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10015-101C6 (esophagus, adult, pool1)
- 10658-109C1
- 10660-109C3
- 10661-109C4
- 10665-109C8
- 11507-119G4 (Esophageal Epithelial Cells, donor1)
- 11508-119G5 (Smooth Muscle Cells - Esophageal, donor1)
- 11587-120G3 (Esophageal Epithelial Cells, donor2)
- 11588-120G4 (Smooth Muscle Cells - Esophageal, donor2)
- 11668-122G3 (Esophageal Epithelial Cells, donor3)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001043 (esophagus), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 2.39e-66 | FFCP PHASE1:Hg19::chr12:53200931..53200932,-#_3fa8eaf43b112bf508a1d850ddaa1a07 | p@chr12:53200931..53200932, - |
| 2.39e-66 | FFCP PHASE2:Hg19::chr12:53202541..53202544,-#_3fa8eaf43b112bf508a1d850ddaa1a07 | p@chr12:53202541..53202544, - |
| 2.39e-66 | FFCP PHASE1:Hg19::chr12:8995874..8995875,+#_3fa8eaf43b112bf508a1d850ddaa1a07 | p26@A2ML1 |
| 2.39e-66 | FFCP PHASE2:Hg19::chr7:46193488..46193497,+#_3fa8eaf43b112bf508a1d850ddaa1a07 | p@chr7:46193488..46193497, + |
| 2.39e-66 | FFCP PHASE1:Hg19::chr12:53202541..53202544,-#_3fa8eaf43b112bf508a1d850ddaa1a07 | p@chr12:53202541..53202544, - |
| 2.39e-66 | FFCP PHASE1:Hg19::chr7:46193488..46193497,+#_3fa8eaf43b112bf508a1d850ddaa1a07 | p@chr7:46193488..46193497, + |
| 2.39e-66 | FFCP PHASE2:Hg19::chr12:9008112..9008120,+#_3fa8eaf43b112bf508a1d850ddaa1a07 | p25@A2ML1 |
| 2.39e-66 | FFCP PHASE1:Hg19::chr12:9008112..9008120,+#_3fa8eaf43b112bf508a1d850ddaa1a07 | p25@A2ML1 |
| 2.39e-66 | FFCP PHASE2:Hg19::chr12:9010623..9010637,+#_3fa8eaf43b112bf508a1d850ddaa1a07 | p@chr12:9010623..9010637, + |
| 2.39e-66 | FFCP PHASE1:Hg19::chr12:9010623..9010637,+#_3fa8eaf43b112bf508a1d850ddaa1a07 | p@chr12:9010623..9010637, + |
| 2.39e-66 | FFCP PHASE2:Hg19::chr12:53201644..53201647,-#_3fa8eaf43b112bf508a1d850ddaa1a07 | p18@KRT4 |
| 2.39e-66 | FFCP PHASE1:Hg19::chr12:53201644..53201647,-#_3fa8eaf43b112bf508a1d850ddaa1a07 | p18@KRT4 |
| 2.39e-66 | FFCP PHASE2:Hg19::chr1:118570971..118570976,-#_3fa8eaf43b112bf508a1d850ddaa1a07 | p@chr1:118570971..118570976, - |
| 2.39e-66 | FFCP PHASE2:Hg19::chr12:53200931..53200932,-#_3fa8eaf43b112bf508a1d850ddaa1a07 | p@chr12:53200931..53200932, - |
| 2.39e-66 | FFCP PHASE1:Hg19::chr1:118570971..118570976,-#_3fa8eaf43b112bf508a1d850ddaa1a07 | p@chr1:118570971..118570976, - |
| 2.39e-66 | FFCP PHASE2:Hg19::chr12:8995874..8995875,+#_3fa8eaf43b112bf508a1d850ddaa1a07 | p26@A2ML1 |
| 1.28e-53 | FFCP PHASE2:Hg19::chr10:105495838..105495848,-#_8773a9e3560d6f599e472f40fcf63c16 | p@chr10:105495838..105495848, - |
| 1.28e-53 | FFCP PHASE1:Hg19::chr10:105495838..105495848,-#_8773a9e3560d6f599e472f40fcf63c16 | p@chr10:105495838..105495848, - |
| 3.94e-34 | FFCP PHASE2:Hg19::chr11:8795787..8795804,-#_8ae68dc71e3a043ad23ca34958d45c53 | p26@ST5 |
| 3.94e-34 | FFCP PHASE1:Hg19::chr11:8795787..8795804,-#_8ae68dc71e3a043ad23ca34958d45c53 | p26@ST5 |
| 4.27e-34 | FFCP PHASE1:Hg19::chr7:75927025..75927030,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr7:75927025..75927030, - |
| 4.27e-34 | FFCP PHASE1:Hg19::chr15:90030191..90030200,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr15:90030191..90030200, - |
| 4.27e-34 | FFCP PHASE1:Hg19::chr6:31023284..31023287,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr6:31023284..31023287, - |
| 4.27e-34 | FFCP PHASE2:Hg19::chr6:31023284..31023287,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr6:31023284..31023287, - |
| 4.27e-34 | FFCP PHASE2:Hg19::chr17:39659243..39659248,+#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr17:39659243..39659248, + |
| 4.27e-34 | FFCP PHASE2:Hg19::chr3:259245..259270,+#_321618ec4a15cc7539d68a4c0fcdd7e5 | p19@CHL1 |
| 4.27e-34 | FFCP PHASE2:Hg19::chr18:29006862..29006869,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr18:29006862..29006869, - |
| 4.27e-34 | FFCP PHASE2:Hg19::chr14:80697396..80697402,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p25@DIO2 |
| 4.27e-34 | FFCP PHASE1:Hg19::chr16:70602961..70602972,+#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr16:70602961..70602972, + |
| 4.27e-34 | FFCP PHASE1:Hg19::chr3:259245..259270,+#_321618ec4a15cc7539d68a4c0fcdd7e5 | p19@CHL1 |
| 4.27e-34 | FFCP PHASE1:Hg19::chr6:30043497..30043501,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p4@RNF39 |
| 4.27e-34 | FFCP PHASE2:Hg19::chr6:30043497..30043501,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p4@RNF39 |
| 4.27e-34 | FFCP PHASE2:Hg19::chr12:53201621..53201631,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p14@KRT4 |
| 4.27e-34 | FFCP PHASE1:Hg19::chr12:53201621..53201631,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p14@KRT4 |
| 4.27e-34 | FFCP PHASE1:Hg19::chr14:80697396..80697402,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p25@DIO2 |
| 4.27e-34 | FFCP PHASE1:Hg19::chr18:29006862..29006869,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr18:29006862..29006869, - |
| 4.27e-34 | FFCP PHASE2:Hg19::chr8:126017792..126017808,+#_321618ec4a15cc7539d68a4c0fcdd7e5 | p15@SQLE |
| 4.27e-34 | FFCP PHASE1:Hg19::chr17:39659243..39659248,+#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr17:39659243..39659248, + |
| 4.27e-34 | FFCP PHASE2:Hg19::chr1:152975795..152975798,+#_321618ec4a15cc7539d68a4c0fcdd7e5 | p22@AB587575 |
| 4.27e-34 | FFCP PHASE1:Hg19::chr6:30954191..30954198,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr6:30954191..30954198, - |
| 4.27e-34 | FFCP PHASE2:Hg19::chr8:17611395..17611403,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p50@MTUS1 |
| 4.27e-34 | FFCP PHASE2:Hg19::chr6:30954191..30954198,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr6:30954191..30954198, - |
| 4.27e-34 | FFCP PHASE1:Hg19::chr8:126017792..126017808,+#_321618ec4a15cc7539d68a4c0fcdd7e5 | p15@SQLE |
| 4.27e-34 | FFCP PHASE2:Hg19::chr7:75926905..75926913,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr7:75926905..75926913, - |
| 4.27e-34 | FFCP PHASE1:Hg19::chr1:152975795..152975798,+#_321618ec4a15cc7539d68a4c0fcdd7e5 | p22@AB587575 |
| 4.27e-34 | FFCP PHASE1:Hg19::chr6:30954100..30954103,+#_321618ec4a15cc7539d68a4c0fcdd7e5 | p10@MUC21 |
| 4.27e-34 | FFCP PHASE2:Hg19::chr6:30954100..30954103,+#_321618ec4a15cc7539d68a4c0fcdd7e5 | p10@MUC21 |
| 4.27e-34 | FFCP PHASE1:Hg19::chr8:17611395..17611403,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p50@MTUS1 |
| 4.27e-34 | FFCP PHASE2:Hg19::chr16:70602961..70602972,+#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr16:70602961..70602972, + |
| 4.27e-34 | FFCP PHASE1:Hg19::chr7:75926905..75926913,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr7:75926905..75926913, - |
| 4.27e-34 | FFCP PHASE2:Hg19::chr15:90030191..90030200,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr15:90030191..90030200, - |
| 4.27e-34 | FFCP PHASE2:Hg19::chr7:75927025..75927030,-#_321618ec4a15cc7539d68a4c0fcdd7e5 | p@chr7:75927025..75927030, - |
| 5.96e-34 | FFCP PHASE2:Hg19::chr1:55272540..55272552,+#_77fb3204fbe1972a3a05bf6aad42c645 | p@chr1:55272540..55272552, + |
| 5.96e-34 | FFCP PHASE1:Hg19::chr15:99637405..99637416,+#_77fb3204fbe1972a3a05bf6aad42c645 | p@chr15:99637405..99637416, + |
| 5.96e-34 | FFCP PHASE1:Hg19::chr1:55272540..55272552,+#_77fb3204fbe1972a3a05bf6aad42c645 | p@chr1:55272540..55272552, + |
| 5.96e-34 | FFCP PHASE1:Hg19::chr15:71839224..71839247,+#_77fb3204fbe1972a3a05bf6aad42c645 | p11@THSD4 |
| 5.96e-34 | FFCP PHASE1:Hg19::chr17:39657548..39657549,-#_77fb3204fbe1972a3a05bf6aad42c645 | p@chr17:39657548..39657549, - |
| 5.96e-34 | FFCP PHASE2:Hg19::chr3:37061825..37061832,+#_77fb3204fbe1972a3a05bf6aad42c645 | p@chr3:37061825..37061832, + |
| 5.96e-34 | FFCP PHASE1:Hg19::chr3:37061825..37061832,+#_77fb3204fbe1972a3a05bf6aad42c645 | p@chr3:37061825..37061832, + |
| 5.96e-34 | FFCP PHASE2:Hg19::chr15:101069325..101069330,-#_77fb3204fbe1972a3a05bf6aad42c645 | p7@CERS3 |
| 5.96e-34 | FFCP PHASE2:Hg19::chr2:31476953..31476977,+#_77fb3204fbe1972a3a05bf6aad42c645 | p@chr2:31476953..31476977, + |
| 5.96e-34 | FFCP PHASE1:Hg19::chr2:31476953..31476977,+#_77fb3204fbe1972a3a05bf6aad42c645 | p@chr2:31476953..31476977, + |
| 5.96e-34 | FFCP PHASE2:Hg19::chr17:39657548..39657549,-#_77fb3204fbe1972a3a05bf6aad42c645 | p@chr17:39657548..39657549, - |
| 5.96e-34 | FFCP PHASE1:Hg19::chr15:101069325..101069330,-#_77fb3204fbe1972a3a05bf6aad42c645 | p7@CERS3 |
| 5.96e-34 | FFCP PHASE2:Hg19::chr15:99637405..99637416,+#_77fb3204fbe1972a3a05bf6aad42c645 | p@chr15:99637405..99637416, + |
| 5.96e-34 | FFCP PHASE2:Hg19::chr15:71839224..71839247,+#_77fb3204fbe1972a3a05bf6aad42c645 | p11@THSD4 |
| 1.08e-33 | FFCP PHASE1:Hg19::chr17:18907460..18907461,-#_4b7d0da5a1379df5bdbaf2cb45cb5fe2 | p12@FAM83G |
| 1.08e-33 | FFCP PHASE2:Hg19::chr17:18907460..18907461,-#_4b7d0da5a1379df5bdbaf2cb45cb5fe2 | p12@FAM83G |
| 2.62e-23 | FFCP PHASE2:Hg19::chr17:39659331..39659336,-#_284fe9f6ae29ebe07f404dd460ca7793 | p20@KRT13 |
| 2.62e-23 | FFCP PHASE1:Hg19::chr1:152382640..152382645,+#_284fe9f6ae29ebe07f404dd460ca7793 | p@chr1:152382640..152382645, + |
| 2.62e-23 | FFCP PHASE2:Hg19::chr18:29006845..29006854,-#_284fe9f6ae29ebe07f404dd460ca7793 | p@chr18:29006845..29006854, - |
| 2.62e-23 | FFCP PHASE1:Hg19::chr1:153362896..153362903,-#_284fe9f6ae29ebe07f404dd460ca7793 | p5@S100A8 |
| 2.62e-23 | FFCP PHASE1:Hg19::chr20:46821059..46821069,+#_284fe9f6ae29ebe07f404dd460ca7793 | p@chr20:46821059..46821069, + |
| 2.62e-23 | FFCP PHASE2:Hg19::chr1:153362896..153362903,-#_284fe9f6ae29ebe07f404dd460ca7793 | p5@S100A8 |
| 2.62e-23 | FFCP PHASE2:Hg19::chr2:178179611..178179619,-#_284fe9f6ae29ebe07f404dd460ca7793 | p4@ENST00000443132 |
| 2.62e-23 | FFCP PHASE2:Hg19::chr12:53232854..53232870,-#_284fe9f6ae29ebe07f404dd460ca7793 | p@chr12:53232854..53232870, - |
| 2.62e-23 | FFCP PHASE1:Hg19::chr12:53232854..53232870,-#_284fe9f6ae29ebe07f404dd460ca7793 | p@chr12:53232854..53232870, - |
| 2.62e-23 | FFCP PHASE1:Hg19::chr18:29006845..29006854,-#_284fe9f6ae29ebe07f404dd460ca7793 | p@chr18:29006845..29006854, - |
| 2.62e-23 | FFCP PHASE2:Hg19::chr3:124535316..124535340,+#_284fe9f6ae29ebe07f404dd460ca7793 | p@chr3:124535316..124535340, + |
| 2.62e-23 | FFCP PHASE1:Hg19::chr2:178179611..178179619,-#_284fe9f6ae29ebe07f404dd460ca7793 | p4@ENST00000443132 |
| 2.62e-23 | FFCP PHASE2:Hg19::chr11:67786884..67786893,+#_284fe9f6ae29ebe07f404dd460ca7793 | p2@AK129943 |
| 2.62e-23 | FFCP PHASE1:Hg19::chr17:39659331..39659336,-#_284fe9f6ae29ebe07f404dd460ca7793 | p20@KRT13 |
| 2.62e-23 | FFCP PHASE1:Hg19::chr3:124535316..124535340,+#_284fe9f6ae29ebe07f404dd460ca7793 | p@chr3:124535316..124535340, + |
| 2.62e-23 | FFCP PHASE1:Hg19::chr6:30954084..30954093,-#_284fe9f6ae29ebe07f404dd460ca7793 | p@chr6:30954084..30954093, - |
| 2.62e-23 | FFCP PHASE2:Hg19::chr6:30954084..30954093,-#_284fe9f6ae29ebe07f404dd460ca7793 | p@chr6:30954084..30954093, - |
| 2.62e-23 | FFCP PHASE2:Hg19::chr12:53673418..53673427,+#_284fe9f6ae29ebe07f404dd460ca7793 | p9@ESPL1 |
| 2.62e-23 | FFCP PHASE2:Hg19::chr12:53201485..53201493,-#_284fe9f6ae29ebe07f404dd460ca7793 | p15@KRT4 |
| 2.62e-23 | FFCP PHASE1:Hg19::chr12:53673418..53673427,+#_284fe9f6ae29ebe07f404dd460ca7793 | p9@ESPL1 |
| 2.62e-23 | FFCP PHASE1:Hg19::chr11:67786884..67786893,+#_284fe9f6ae29ebe07f404dd460ca7793 | p2@AK129943 |
| 2.62e-23 | FFCP PHASE2:Hg19::chr19:51530837..51530842,-#_284fe9f6ae29ebe07f404dd460ca7793 | p10@KLK11 |
| 2.62e-23 | FFCP PHASE2:Hg19::chr1:152382640..152382645,+#_284fe9f6ae29ebe07f404dd460ca7793 | p@chr1:152382640..152382645, + |
| 2.62e-23 | FFCP PHASE2:Hg19::chr20:46821059..46821069,+#_284fe9f6ae29ebe07f404dd460ca7793 | p@chr20:46821059..46821069, + |
| 2.62e-23 | FFCP PHASE1:Hg19::chr12:53201485..53201493,-#_284fe9f6ae29ebe07f404dd460ca7793 | p15@KRT4 |
| 2.62e-23 | FFCP PHASE1:Hg19::chr19:51530837..51530842,-#_284fe9f6ae29ebe07f404dd460ca7793 | p10@KLK11 |
| 3.27e-23 | FFCP PHASE2:Hg19::chr1:152384720..152384731,-#_8618fd1ea389a2559894397ac0380954 | p3@CU689016 |
| 3.27e-23 | FFCP PHASE2:Hg19::chr20:2321399..2321407,+#_8618fd1ea389a2559894397ac0380954 | p@chr20:2321399..2321407, + |
| 3.27e-23 | FFCP PHASE1:Hg19::chr5:175837672..175837682,-#_8618fd1ea389a2559894397ac0380954 | p@chr5:175837672..175837682, - |
| 3.27e-23 | FFCP PHASE2:Hg19::chr5:175837672..175837682,-#_8618fd1ea389a2559894397ac0380954 | p@chr5:175837672..175837682, - |
| 3.27e-23 | FFCP PHASE2:Hg19::chr3:187930719..187930729,+#_8618fd1ea389a2559894397ac0380954 | p61@LPP |
| 3.27e-23 | FFCP PHASE2:Hg19::chr17:39659966..39659969,-#_8618fd1ea389a2559894397ac0380954 | p@chr17:39659966..39659969, - |
Property "Property value" (as page type) with input value "UBPROP:0000001 "Anterior end of the alimentary canal lined with smooth muscle. Bounded anteriorly by a constriction in the pharynx. Bounded posteriorly by and increase in circular and/or longitudinal smooth muscle associated with the stomach.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
