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CL:0000040

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Name:monoblast
Namespace:FANTOM
Definition:"A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus." [GOC:add, http://www.clt.astate.edu/wwilliam/, http://www.copewithcytokines.de, PMID:1104740]
Xrefs:
links:
FMA:83553
Synonyms: "CFU-M" RELATED []
"colony forming unit macrophage" RELATED []
"monocyte stem cell" RELATED []
Comments:Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.


Ontology association
Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.

link to ontology dataset
data


Parents

is_a:CL:0000763(myeloid cell),CL:0002194(monopoietic cell)
develops_from:CL:0002009(macrophage dendritic cell progenitor)



Children


develops from:CL:0000559 (promonocyte)

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Cell ontology.




Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000040 (monoblast), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
1.04e-147FFCP PHASE1:Hg19::chr7:77050554..77050601,+#_102b57f152dc3cb6d15cb4ae40e46f39p@chr7:77050554..77050601, +
1.04e-147FFCP PHASE2:Hg19::chr7:77050554..77050601,+#_102b57f152dc3cb6d15cb4ae40e46f39p@chr7:77050554..77050601, +
5.64e-145FFCP PHASE2:Hg19::chr19:18288651..18288682,+#_59bd3fe86fc67b7fe468dc7f0f2ea18bp5@IFI30
5.64e-145FFCP PHASE1:Hg19::chr19:18288651..18288682,+#_59bd3fe86fc67b7fe468dc7f0f2ea18bp5@IFI30
4.95e-140FFCP PHASE1:Hg19::chr19:18288828..18288861,+#_a36944be3e8bea1bbd3ec01b471937f1p7@IFI30
4.95e-140FFCP PHASE2:Hg19::chr19:18288828..18288861,+#_a36944be3e8bea1bbd3ec01b471937f1p7@IFI30
5.06e-140FFCP PHASE2:Hg19::chr5:180242646..180242657,-#_c41c7f4ffb4814a16b0b6ed50627e88cp15@MGAT1
5.06e-140FFCP PHASE1:Hg19::chr5:180242646..180242657,-#_c41c7f4ffb4814a16b0b6ed50627e88cp15@MGAT1
1.31e-139FFCP PHASE2:Hg19::chr1:161188661..161188679,+#_a3a922caa6095f88eb74a493ef12823ap@chr1:161188661..161188679, +
1.31e-139FFCP PHASE1:Hg19::chr1:161188661..161188679,+#_a3a922caa6095f88eb74a493ef12823ap@chr1:161188661..161188679, +
5.87e-136FFCP PHASE1:Hg19::chr2:38358217..38358244,+#_90a3154d215d0c3cc62fd2684293389bp1@CYP1B1-AS1
5.87e-136FFCP PHASE2:Hg19::chr2:38358217..38358244,+#_90a3154d215d0c3cc62fd2684293389bp1@CYP1B1-AS1
5.37e-135FFCP PHASE2:Hg19::chr4:185314125..185314143,-#_21deb975ec0691e25c3617bd83fb8b24p@chr4:185314125..185314143, -
5.37e-135FFCP PHASE1:Hg19::chr4:185314125..185314143,-#_21deb975ec0691e25c3617bd83fb8b24p@chr4:185314125..185314143, -
3.75e-134FFCP PHASE1:Hg19::chr3:149531627..149531651,+#_3d811ecdbf5fc895479264b703fe4ed1p7@RNF13
3.75e-134FFCP PHASE2:Hg19::chr3:149531627..149531651,+#_3d811ecdbf5fc895479264b703fe4ed1p7@RNF13
6.15e-134FFCP PHASE1:Hg19::chr2:119726719..119726744,+#_70b2dfb839229699dce935e6cb163deep@chr2:119726719..119726744, +
6.15e-134FFCP PHASE2:Hg19::chr2:119726719..119726744,+#_70b2dfb839229699dce935e6cb163deep@chr2:119726719..119726744, +
7.41e-134FFCP PHASE2:Hg19::chr1:161187824..161187847,+#_4741dea864e2b4e65bc8361187188027p@chr1:161187824..161187847, +
7.41e-134FFCP PHASE1:Hg19::chr1:161187824..161187847,+#_4741dea864e2b4e65bc8361187188027p@chr1:161187824..161187847, +
2.24e-133FFCP PHASE1:Hg19::chr17:7482481..7482508,-#_a6e11dd5969514a7fb8ba63d1e778bafp@chr17:7482481..7482508, -
2.24e-133FFCP PHASE2:Hg19::chr17:7482481..7482508,-#_a6e11dd5969514a7fb8ba63d1e778bafp@chr17:7482481..7482508, -
4.55e-133FFCP PHASE2:Hg19::chr19:18286116..18286156,+#_194f003e09b739ceadd46454ed778ff9p@chr19:18286116..18286156, +
4.55e-133FFCP PHASE1:Hg19::chr19:18286116..18286156,+#_194f003e09b739ceadd46454ed778ff9p@chr19:18286116..18286156, +
1.09e-132FFCP PHASE2:Hg19::chr4:185314151..185314178,-#_f977e0db84003918acae04c7d5842a5ep@chr4:185314151..185314178, -
1.09e-132FFCP PHASE1:Hg19::chr4:185314151..185314178,-#_f977e0db84003918acae04c7d5842a5ep@chr4:185314151..185314178, -
1.13e-132FFCP PHASE1:Hg19::chr5:131280548..131280574,-#_06b163e292541b15a2f3beded661dc6ap1@ENST00000425320
1.13e-132FFCP PHASE2:Hg19::chr5:131280548..131280574,-#_06b163e292541b15a2f3beded661dc6ap1@ENST00000425320
1.42e-132FFCP PHASE2:Hg19::chr2:145429606..145429658,+#_afcb2fb18336b8be21837e27df17d9e7p@chr2:145429606..145429658, +
1.42e-132FFCP PHASE1:Hg19::chr2:145429606..145429658,+#_afcb2fb18336b8be21837e27df17d9e7p@chr2:145429606..145429658, +
1.21e-131FFCP PHASE1:Hg19::chr19:18288064..18288080,+#_b3ff82b3177da763bb4ab0017397fbf0p@chr19:18288064..18288080, +
1.21e-131FFCP PHASE2:Hg19::chr19:18288064..18288080,+#_b3ff82b3177da763bb4ab0017397fbf0p@chr19:18288064..18288080, +
2.27e-131FFCP PHASE2:Hg19::chr1:150724282..150724308,-#_40d6f9d99dd17d795ce3dc2f76252548p8@CTSS
2.27e-131FFCP PHASE1:Hg19::chr1:150724282..150724308,-#_40d6f9d99dd17d795ce3dc2f76252548p8@CTSS
2.82e-131FFCP PHASE1:Hg19::chrX:37664331..37664352,+#_2b3290d3e2048a9df7b6cb55975115eap@chrX:37664331..37664352, +
2.82e-131FFCP PHASE2:Hg19::chrX:37664331..37664352,+#_2b3290d3e2048a9df7b6cb55975115eap@chrX:37664331..37664352, +
4.07e-131FFCP PHASE1:Hg19::chr4:185314188..185314207,-#_f7c54edfc067c8cf57396cb5afb1977fp@chr4:185314188..185314207, -
4.07e-131FFCP PHASE2:Hg19::chr4:185314188..185314207,-#_f7c54edfc067c8cf57396cb5afb1977fp@chr4:185314188..185314207, -
5.24e-131FFCP PHASE2:Hg19::chr15:65174546..65174583,-#_c178ca20fec073d75a806659bb85789cp@chr15:65174546..65174583, -
5.24e-131FFCP PHASE1:Hg19::chr15:65174546..65174583,-#_c178ca20fec073d75a806659bb85789cp@chr15:65174546..65174583, -
2.76e-130FFCP PHASE2:Hg19::chr4:159727272..159727307,+#_82adf8437c6556a8cd826df68e568934p7@FNIP2
2.76e-130FFCP PHASE1:Hg19::chr4:159727272..159727307,+#_82adf8437c6556a8cd826df68e568934p7@FNIP2
3.58e-130FFCP PHASE1:Hg19::chr1:161188746..161188758,+#_b66d4803be6314df7a3352a112eeff33p@chr1:161188746..161188758, +
3.58e-130FFCP PHASE2:Hg19::chr1:161188746..161188758,+#_b66d4803be6314df7a3352a112eeff33p@chr1:161188746..161188758, +
2.17e-129FFCP PHASE2:Hg19::chr20:1517991..1518011,-#_e3c25d87f2c558739a6a5d3f2efa0522p@chr20:1517991..1518011, -
2.17e-129FFCP PHASE1:Hg19::chr20:1517991..1518011,-#_e3c25d87f2c558739a6a5d3f2efa0522p@chr20:1517991..1518011, -
3.46e-129FFCP PHASE2:Hg19::chr18:2847062..2847071,+#_b438bf2c1b2b4b03dcab5f297d8cf515p7@EMILIN2
3.46e-129FFCP PHASE1:Hg19::chr18:2847062..2847071,+#_b438bf2c1b2b4b03dcab5f297d8cf515p7@EMILIN2
1.47e-128FFCP PHASE1:Hg19::chr19:18288514..18288554,+#_60b688a8880e20917480e69e4203049bp6@IFI30
1.47e-128FFCP PHASE2:Hg19::chr19:18288514..18288554,+#_60b688a8880e20917480e69e4203049bp6@IFI30
1.78e-128FFCP PHASE2:Hg19::chr19:18288914..18288931,-#_d5ef1b1ee934e4194ca8716b48979a9fp5@CU676849, p5@CU689079
1.78e-128FFCP PHASE1:Hg19::chr19:18288914..18288931,-#_d5ef1b1ee934e4194ca8716b48979a9fp5@CU676849, p5@CU689079
2.01e-128FFCP PHASE2:Hg19::chr5:180242576..180242585,-#_730634d1674e108b07f6a2eb6edfc442p12@MGAT1
2.01e-128FFCP PHASE1:Hg19::chr5:180242576..180242585,-#_730634d1674e108b07f6a2eb6edfc442p12@MGAT1
2.32e-127FFCP PHASE1:Hg19::chr17:40168698..40168726,-#_abfeb65177e726fd323583a223585b2cp1@AK126179
2.32e-127FFCP PHASE2:Hg19::chr17:40168698..40168726,-#_abfeb65177e726fd323583a223585b2cp1@AK126179
2.49e-127FFCP PHASE2:Hg19::chr17:7483714..7483726,+#_e0d88c96369c96b1e5d91962e639251fp@chr17:7483714..7483726, +
2.49e-127FFCP PHASE1:Hg19::chr17:7483714..7483726,+#_e0d88c96369c96b1e5d91962e639251fp@chr17:7483714..7483726, +
1.19e-126FFCP PHASE1:Hg19::chr22:46998103..46998127,-#_84e611626b660d30260e46e90b0663f8p@chr22:46998103..46998127, -
1.19e-126FFCP PHASE2:Hg19::chr22:46998103..46998127,-#_84e611626b660d30260e46e90b0663f8p@chr22:46998103..46998127, -
2.16e-126FFCP PHASE2:Hg19::chr19:18285955..18285972,+#_fba4086eacf5afd1da98627bce89761fp@chr19:18285955..18285972, +
2.16e-126FFCP PHASE1:Hg19::chr19:18285955..18285972,+#_fba4086eacf5afd1da98627bce89761fp@chr19:18285955..18285972, +
3.83e-126FFCP PHASE1:Hg19::chr19:51625924..51625942,+#_86f653e2de32b7f766441eccf1de0b97p@chr19:51625924..51625942, +
3.83e-126FFCP PHASE2:Hg19::chr19:51625924..51625942,+#_86f653e2de32b7f766441eccf1de0b97p@chr19:51625924..51625942, +
7.27e-126FFCP PHASE2:Hg19::chr4:185266972..185267007,+#_316b79ce5423accaad38c75d10fde2e7p@chr4:185266972..185267007, +
7.27e-126FFCP PHASE1:Hg19::chr4:185266972..185267007,+#_316b79ce5423accaad38c75d10fde2e7p@chr4:185266972..185267007, +
2.66e-125FFCP PHASE2:Hg19::chrX:152086449..152086473,+#_eca2e4b93dc4d2c6442809775a8a4a1ep4@ZNF185
2.66e-125FFCP PHASE1:Hg19::chrX:152086449..152086473,+#_eca2e4b93dc4d2c6442809775a8a4a1ep4@ZNF185
7.73e-125FFCP PHASE1:Hg19::chr2:145276939..145276960,+#_be349a1e8de9f6b6bb88b623691564afp2@ZEB2-AS1
7.73e-125FFCP PHASE2:Hg19::chr2:145276939..145276960,+#_be349a1e8de9f6b6bb88b623691564afp2@ZEB2-AS1
8.12e-125FFCP PHASE2:Hg19::chr15:59469817..59469836,+#_fcd4c25a59dc3dfdb0b62f44d4b2be7fp@chr15:59469817..59469836, +
8.12e-125FFCP PHASE1:Hg19::chr15:59469817..59469836,+#_fcd4c25a59dc3dfdb0b62f44d4b2be7fp@chr15:59469817..59469836, +
1.56e-124FFCP PHASE2:Hg19::chr20:1517945..1517963,-#_8765b9a28df16066fc15597555102345p@chr20:1517945..1517963, -
1.56e-124FFCP PHASE1:Hg19::chr20:1517945..1517963,-#_8765b9a28df16066fc15597555102345p@chr20:1517945..1517963, -
1.65e-124FFCP PHASE1:Hg19::chr8:116588888..116588904,+#_8fb7935f71e7fff85d15f3c240e92a0cp@chr8:116588888..116588904, +
1.65e-124FFCP PHASE2:Hg19::chr8:116588888..116588904,+#_8fb7935f71e7fff85d15f3c240e92a0cp@chr8:116588888..116588904, +
1.87e-124FFCP PHASE2:Hg19::chr1:161188686..161188721,+#_db871f724dd1cb535b1e2fd5e1c5a8f9+, p@chr1:161188686..161188721
1.87e-124FFCP PHASE1:Hg19::chr1:161188686..161188721,+#_db871f724dd1cb535b1e2fd5e1c5a8f9p@chr1:161188686..161188721, +
7.08e-124FFCP PHASE2:Hg19::chr5:77845080..77845099,-#_1e146dfffc22e0314bc63ce44a75a785p10@LHFPL2
7.08e-124FFCP PHASE1:Hg19::chr5:77845080..77845099,-#_1e146dfffc22e0314bc63ce44a75a785p10@LHFPL2
1.48e-123FFCP PHASE2:Hg19::chr9:137264970..137264982,+#_aa7511b85f2a1e3cad5c3a78d9f8bfecp@chr9:137264970..137264982, +
1.48e-123FFCP PHASE1:Hg19::chr9:137264970..137264982,+#_aa7511b85f2a1e3cad5c3a78d9f8bfecp@chr9:137264970..137264982, +
6.01e-123FFCP PHASE2:Hg19::chr17:47294661..47294681,+#_9026c774fa910cfd7e1ee56534abe5bcp@chr17:47294661..47294681, +
6.01e-123FFCP PHASE1:Hg19::chr17:47294661..47294681,+#_9026c774fa910cfd7e1ee56534abe5bcp@chr17:47294661..47294681, +
1.14e-122FFCP PHASE1:Hg19::chr1:108593061..108593077,+#_dfae09b8f2f4c1d38c0fe0a717999444p@chr1:108593061..108593077, +
1.14e-122FFCP PHASE2:Hg19::chr1:108593061..108593077,+#_dfae09b8f2f4c1d38c0fe0a717999444p@chr1:108593061..108593077, +
2.07e-122FFCP PHASE2:Hg19::chrX:153286067..153286101,-#_929e38fa12176c43a36d6661debcb4c4p@chrX:153286067..153286101, -
2.07e-122FFCP PHASE1:Hg19::chrX:153286067..153286101,-#_929e38fa12176c43a36d6661debcb4c4p@chrX:153286067..153286101, -
3.07e-122FFCP PHASE2:Hg19::chr14:103587759..103587770,+#_cc6bdb2fd862874483ad1315c85b8a4dp@chr14:103587759..103587770, +
3.07e-122FFCP PHASE1:Hg19::chr14:103587759..103587770,+#_cc6bdb2fd862874483ad1315c85b8a4dp@chr14:103587759..103587770, +
7.82e-122FFCP PHASE1:Hg19::chr1:17945095..17945126,+#_fc43791f170e5292958c3443d3afaa3bp7@ARHGEF10L
7.82e-122FFCP PHASE2:Hg19::chr1:17945095..17945126,+#_fc43791f170e5292958c3443d3afaa3bp7@ARHGEF10L
3.27e-121FFCP PHASE2:Hg19::chr16:50313426..50313459,+#_07ec231a4b78a6b79863b8737a6ecb9ap@chr16:50313426..50313459, +
3.27e-121FFCP PHASE1:Hg19::chr16:50313426..50313459,+#_07ec231a4b78a6b79863b8737a6ecb9ap@chr16:50313426..50313459, +
3.74e-121FFCP PHASE1:Hg19::chr10:20105868..20105875,+#_33e63c6c9a3afe9a1a7fb4976e44b15cp8@PLXDC2
3.74e-121FFCP PHASE2:Hg19::chr10:20105868..20105875,+#_33e63c6c9a3afe9a1a7fb4976e44b15cp8@PLXDC2
7.36e-121FFCP PHASE2:Hg19::chr1:150705526..150705571,-#_9ea519f00fc69383f66ba0e36a069dd6-, p@chr1:150705526..150705571
7.36e-121FFCP PHASE1:Hg19::chr1:150705526..150705571,-#_9ea519f00fc69383f66ba0e36a069dd6p@chr1:150705526..150705571, -
1.75e-120FFCP PHASE1:Hg19::chr19:18283959..18283993,+#_b1cab155c87608b88a6c19df27e98097p@chr19:18283959..18283993, +
1.75e-120FFCP PHASE2:Hg19::chr19:18283959..18283993,+#_b1cab155c87608b88a6c19df27e98097p@chr19:18283959..18283993, +


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