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Coexpression cluster:C148

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Full id: C148_kidney_small_epididymis_pancreas_serous_duodenum_temporal



Phase1 CAGE Peaks

Hg19::chr10:17171785..17171816,-p1@CUBN
Hg19::chr10:17171817..17171829,-p3@CUBN
Hg19::chr10:17171832..17171835,-p7@CUBN
Hg19::chr10:17171871..17171882,-p4@CUBN
Hg19::chr10:45406779..45406811,+p1@TMEM72
Hg19::chr10:45406822..45406831,+p6@TMEM72
Hg19::chr10:45406850..45406891,+p2@TMEM72
Hg19::chr10:45406899..45406917,+p5@TMEM72
Hg19::chr10:54725058..54725064,-p@chr10:54725058..54725064
-
Hg19::chr11:45943169..45943198,+p2@GYLTL1B
Hg19::chr11:58710802..58710822,+p4@GLYATL1
Hg19::chr11:66634017..66634026,-p@chr11:66634017..66634026
-
Hg19::chr11:66634028..66634039,-p@chr11:66634028..66634039
-
Hg19::chr12:101604010..101604021,-p1@SLC5A8
Hg19::chr12:49394840..49394845,-p@chr12:49394840..49394845
-
Hg19::chr12:50366724..50366735,+p2@AQP6
Hg19::chr12:72668682..72668691,-p1@ENST00000552396
Hg19::chr13:42976000..42976034,+p@chr13:42976000..42976034
+
Hg19::chr13:44023202..44023209,-p@chr13:44023202..44023209
-
Hg19::chr13:60162219..60162241,-p@chr13:60162219..60162241
-
Hg19::chr14:64331100..64331111,+p18@SYNE2
Hg19::chr14:76777051..76777061,+p2@ESRRB
Hg19::chr15:33442763..33442799,-p@chr15:33442763..33442799
-
Hg19::chr15:35806202..35806210,-p@chr15:35806202..35806210
-
Hg19::chr15:54129731..54129740,+p@chr15:54129731..54129740
+
Hg19::chr15:54129795..54129813,+p@chr15:54129795..54129813
+
Hg19::chr15:54129815..54129824,+p@chr15:54129815..54129824
+
Hg19::chr15:58790059..58790070,-p19@ALDH1A2
Hg19::chr15:69854732..69854737,+p@chr15:69854732..69854737
+
Hg19::chr15:72447481..72447494,+p@chr15:72447481..72447494
+
Hg19::chr15:72447905..72447946,+p@chr15:72447905..72447946
+
Hg19::chr15:72448034..72448041,+p@chr15:72448034..72448041
+
Hg19::chr15:74504560..74504574,-p@chr15:74504560..74504574
-
Hg19::chr15:74504597..74504602,-p@chr15:74504597..74504602
-
Hg19::chr15:96415419..96415424,-p@chr15:96415419..96415424
-
Hg19::chr15:99857689..99857711,+p@chr15:99857689..99857711
+
Hg19::chr16:67552303..67552342,+p@chr16:67552303..67552342
+
Hg19::chr16:67552347..67552370,+p@chr16:67552347..67552370
+
Hg19::chr16:67562327..67562332,-p@chr16:67562327..67562332
-
Hg19::chr16:7101842..7101875,+p@chr16:7101842..7101875
+
Hg19::chr17:48212716..48212739,+p1@ENST00000451776
Hg19::chr18:42782953..42782960,+p@chr18:42782953..42782960
+
Hg19::chr18:42783022..42783033,+p@chr18:42783022..42783033
+
Hg19::chr18:42783125..42783139,+p@chr18:42783125..42783139
+
Hg19::chr18:55864988..55864995,+p@chr18:55864988..55864995
+
Hg19::chr19:12348371..12348386,-p5@ZNF44
Hg19::chr19:36343357..36343389,-p1@NPHS1
Hg19::chr19:36343399..36343419,-p@chr19:36343399..36343419
-
Hg19::chr19:40749216..40749225,-p23@AKT2
Hg19::chr1:110950539..110950551,-p3@HBXIP
Hg19::chr1:117021492..117021508,-p1@ENST00000443219
Hg19::chr1:117037504..117037515,-p@chr1:117037504..117037515
-
Hg19::chr1:119911425..119911441,+p1@HAO2
Hg19::chr1:16370271..16370303,+p1@CLCNKB
Hg19::chr1:16370308..16370321,+p3@CLCNKB
Hg19::chr1:171217622..171217676,+p1@FMO1
Hg19::chr1:179545059..179545089,-p1@NPHS2
Hg19::chr1:204135454..204135486,-p1@REN
Hg19::chr1:217311025..217311049,-p10@ESRRG
Hg19::chr1:45115316..45115331,+p@chr1:45115316..45115331
+
Hg19::chr1:6712194..6712206,-p@chr1:6712194..6712206
-
Hg19::chr20:23992230..23992236,+p@chr20:23992230..23992236
+
Hg19::chr21:39628655..39628672,+p2@KCNJ15
Hg19::chr22:50925279..50925294,+p1@MIOX
Hg19::chr2:105490797..105490801,-p@chr2:105490797..105490801
-
Hg19::chr2:105490830..105490865,-p@chr2:105490830..105490865
-
Hg19::chr2:165698497..165698518,-p8@COBLL1
Hg19::chr2:170199190..170199195,-p@chr2:170199190..170199195
-
Hg19::chr2:176994077..176994091,+p8@HOXD8
Hg19::chr2:176994111..176994122,+p10@HOXD8
Hg19::chr2:177029742..177029746,-p@chr2:177029742..177029746
-
Hg19::chr2:178179761..178179765,-p1@ENST00000443132
Hg19::chr2:693025..693036,+p@chr2:693025..693036
+
Hg19::chr2:70021287..70021296,-p@chr2:70021287..70021296
-
Hg19::chr2:73143312..73143323,+p6@EMX1
Hg19::chr3:154876323..154876349,-p@chr3:154876323..154876349
-
Hg19::chr3:190167571..190167577,-p1@TMEM207
Hg19::chr3:38307293..38307310,+p1@SLC22A13
Hg19::chr3:38307313..38307318,+p2@SLC22A13
Hg19::chr3:46919235..46919242,+p11@PTH1R
Hg19::chr3:46921732..46921743,+p8@PTH1R
Hg19::chr4:114257501..114257517,+p77@ANK2
Hg19::chr4:69616649..69616656,-p@chr4:69616649..69616656
-
Hg19::chr4:70465475..70465489,-p2@UGT2A1
p2@UGT2A2
Hg19::chr4:83672072..83672077,-p@chr4:83672072..83672077
-
Hg19::chr4:86748774..86748823,+p33@ARHGAP24
Hg19::chr5:1225494..1225503,+p1@SLC6A18
Hg19::chr5:149111957..149111961,-p@chr5:149111957..149111961
-
Hg19::chr5:150398982..150399013,-p@chr5:150398982..150399013
-
Hg19::chr5:15427092..15427110,-p@chr5:15427092..15427110
-
Hg19::chr5:169532896..169532904,+p1@FOXI1
Hg19::chr5:176811431..176811436,+p1@SLC34A1
Hg19::chr5:31712141..31712148,+p17@PDZD2
Hg19::chr5:32652119..32652129,-p1@ENST00000514225
Hg19::chr5:62986485..62986495,-p@chr5:62986485..62986495
-
Hg19::chr5:72446460..72446471,-p1@ENST00000508255
Hg19::chr5:72469014..72469029,+p1@TMEM174
Hg19::chr5:72469032..72469043,+p2@TMEM174
Hg19::chr6:132723168..132723179,-p8@MOXD1
Hg19::chr6:132723206..132723217,-p@chr6:132723206..132723217
-
Hg19::chr6:132723297..132723305,+p@chr6:132723297..132723305
+
Hg19::chr6:25600260..25600275,+p@chr6:25600260..25600275
+
Hg19::chr6:36210772..36210775,+p1@PNPLA1
Hg19::chr6:51918216..51918243,-p@chr6:51918216..51918243
-
Hg19::chr6:51952328..51952343,-p3@PKHD1
Hg19::chr6:51952347..51952366,-p2@PKHD1
Hg19::chr6:51952367..51952416,-p1@PKHD1
Hg19::chr6:51952418..51952428,-p4@PKHD1
Hg19::chr7:151776079..151776083,+p16@GALNT11
Hg19::chr7:601516..601525,+p1@ENST00000453149
Hg19::chr7:78986665..78986704,-p@chr7:78986665..78986704
-
Hg19::chr8:30309846..30309857,+p@chr8:30309846..30309857
+
Hg19::chr8:58055232..58055235,+p5@ENST00000519314
Hg19::chr9:104231579..104231583,+p2@ENST00000431507
Hg19::chrX:49832271..49832282,+p8@CLCN5


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0007588excretion4.69476442232949e-05
GO:0044459plasma membrane part0.000369429091675413
GO:0044425membrane part0.000491070884924165
GO:0031226intrinsic to plasma membrane0.000743698624798823
GO:0016020membrane0.00167739726344641
GO:0046903secretion0.00251565466945001
GO:0016021integral to membrane0.00251565466945001
GO:0005887integral to plasma membrane0.00251565466945001
GO:0031224intrinsic to membrane0.00251565466945001
GO:0032501multicellular organismal process0.0027725832037263
GO:0012505endomembrane system0.00302972197827191
GO:0031090organelle membrane0.00459785562354463
GO:0005886plasma membrane0.00967451780968439
GO:0005737cytoplasm0.0108855830699133
GO:0044464cell part0.0114132230029425
GO:0016439tRNA-pseudouridine synthase activity0.0152417009374672
GO:0009982pseudouridine synthase activity0.0180476872763543
GO:0005247voltage-gated chloride channel activity0.0199239795702984
GO:0003008system process0.0204564771126168
GO:0022844voltage-gated anion channel activity0.0204708225188006
GO:0004195renin activity0.0204708225188006
GO:0019310inositol catabolic process0.0204708225188006
GO:0050113inositol oxygenase activity0.0204708225188006
GO:0044463cell projection part0.0206159692822967
GO:0051179localization0.0207262091043669
GO:0022857transmembrane transporter activity0.0207262091043669
GO:0009897external side of plasma membrane0.0207262091043669
GO:0008509anion transmembrane transporter activity0.0212055471294034
GO:0044424intracellular part0.0223612507441932
GO:0044444cytoplasmic part0.0223612507441932
GO:0031404chloride ion binding0.0223612507441932
GO:0043168anion binding0.0223612507441932
GO:0043565sequence-specific DNA binding0.0223612507441932
GO:0022892substrate-specific transporter activity0.0223612507441932
GO:0031233intrinsic to external side of plasma membrane0.0223612507441932
GO:0002003angiotensin maturation0.0223612507441932
GO:0016899oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor0.0223612507441932
GO:0031362anchored to external side of plasma membrane0.0223612507441932
GO:0003973(S)-2-hydroxy-acid oxidase activity0.0223612507441932
GO:0060177regulation of angiotensin metabolic process0.0223612507441932
GO:0002002regulation of angiotensin levels in blood0.0223612507441932
GO:0015075ion transmembrane transporter activity0.0223612507441932
GO:0051234establishment of localization0.0223612507441932
GO:0043229intracellular organelle0.0223612507441932
GO:0043226organelle0.0223612507441932
GO:0016866intramolecular transferase activity0.0223612507441932
GO:0015698inorganic anion transport0.0235319780175291
GO:0065008regulation of biological quality0.0261309910929981
GO:0016758transferase activity, transferring hexosyl groups0.0261309910929981
GO:0047961glycine N-acyltransferase activity0.0261309910929981
GO:0001758retinal dehydrogenase activity0.0261309910929981
GO:0001991regulation of systemic arterial blood pressure by circulatory renin-angiotensin0.0261309910929981
GO:0031232extrinsic to external side of plasma membrane0.0261309910929981
GO:0050682AF-2 domain binding0.0261309910929981
GO:0005254chloride channel activity0.0270199451283884
GO:0005496steroid binding0.0281266315934844
GO:0044440endosomal part0.0281266315934844
GO:0010008endosome membrane0.0281266315934844
GO:0006821chloride transport0.0282822587475936
GO:0001561fatty acid alpha-oxidation0.030349766851108
GO:0003081regulation of systemic arterial blood pressure by renin-angiotensin0.030349766851108
GO:0022891substrate-specific transmembrane transporter activity0.030349766851108
GO:0043231intracellular membrane-bound organelle0.030349766851108
GO:0043227membrane-bound organelle0.030349766851108
GO:0022832voltage-gated channel activity0.030349766851108
GO:0005244voltage-gated ion channel activity0.030349766851108
GO:0006820anion transport0.030349766851108
GO:0005253anion channel activity0.0321985993264693
GO:0015321sodium-dependent phosphate transmembrane transporter activity0.0323765415667876
GO:0046716muscle maintenance0.0323765415667876
GO:0015889cobalamin transport0.0323765415667876
GO:0005932basal body0.0323765415667876
GO:0005624membrane fraction0.0323765415667876
GO:0022838substrate specific channel activity0.0329349463092681
GO:0022803passive transmembrane transporter activity0.0335606986987906
GO:0015267channel activity0.0335606986987906
GO:0006810transport0.0356531845066796
GO:00040283-chloroallyl aldehyde dehydrogenase activity0.0356531845066796
GO:0016234inclusion body0.0356531845066796
GO:0000139Golgi membrane0.0356531845066796
GO:0003707steroid hormone receptor activity0.0366536216945416
GO:0007350blastoderm segmentation0.038657912761358
GO:0000578embryonic axis specification0.038657912761358
GO:0008595determination of anterior/posterior axis, embryo0.038657912761358
GO:0007351tripartite regional subdivision0.038657912761358
GO:0050886endocrine process0.0421737357853155
GO:0015250water channel activity0.0421737357853155
GO:0004500dopamine beta-monooxygenase activity0.0421737357853155
GO:0001990regulation of systemic arterial blood pressure by hormone0.0421737357853155
GO:0008194UDP-glycosyltransferase activity0.0448993015915283
GO:0044431Golgi apparatus part0.0448993015915283
GO:0043154negative regulation of caspase activity0.0448993015915283
GO:0031419cobalamin binding0.0448993015915283
GO:0031526brush border membrane0.0448993015915283
GO:0009986cell surface0.0488243607667879
GO:0015101organic cation transmembrane transporter activity0.0488243607667879
GO:0016757transferase activity, transferring glycosyl groups0.0490788170595549
GO:0006066alcohol metabolic process0.0490788170595549
GO:0004879ligand-dependent nuclear receptor activity0.0490788170595549
GO:0005372water transporter activity0.0490788170595549
GO:0004499flavin-containing monooxygenase activity0.0490788170595549
GO:0016715oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen0.0490788170595549
GO:0031253cell projection membrane0.0490788170595549
GO:0009948anterior/posterior axis specification0.0490788170595549
GO:0008301DNA bending activity0.0490788170595549



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
kidney2.63e-1126
kidney mesenchyme2.63e-1126
upper urinary tract2.63e-1126
kidney rudiment2.63e-1126
kidney field2.63e-1126
cavitated compound organ1.15e-0931
urinary system structure9.72e-0747


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.12.52553e-08
MA0004.10.00641363
MA0006.10.108418
MA0007.10.00477566
MA0009.14.61854
MA0014.14.00043e-05
MA0017.11.71956
MA0019.10.227824
MA0024.11.01968
MA0025.10.414602
MA0027.11.383
MA0028.10.00181467
MA0029.10.176856
MA0030.10.167052
MA0031.10.117328
MA0038.10.487726
MA0040.10.719475
MA0041.10.426593
MA0042.11.82586
MA0043.10.0746449
MA0046.113.6057
MA0048.10.000287453
MA0050.10.0542433
MA0051.10.00389865
MA0052.10.414363
MA0055.10.0779123
MA0056.10
MA0057.10.0158055
MA0058.10.00519371
MA0059.10.0819979
MA0060.10.281164
MA0061.10.00325132
MA0063.10
MA0066.10.165111
MA0067.10.239708
MA0068.10.344312
MA0069.12.44349
MA0070.10.501599
MA0071.10.119274
MA0072.10.849675
MA0073.15.72665e-05
MA0074.10.473278
MA0076.10.000177025
MA0077.10.479566
MA0078.10.310235
MA0081.10.0400093
MA0083.10.266732
MA0084.11.73182
MA0087.10.843012
MA0088.10.109502
MA0089.10
MA0090.12.34826
MA0091.10.23794
MA0092.11.32815
MA0093.10.00131127
MA0095.10
MA0098.10
MA0100.10.00488887
MA0101.10.0340037
MA0103.12.02157
MA0105.10.000207242
MA0106.10.614899
MA0107.10.00660217
MA0108.20.514899
MA0109.10
MA0111.10.529424
MA0113.10.957457
MA0114.12.23392
MA0115.10.19201
MA0116.10.451927
MA0117.10.0891848
MA0119.11.80477
MA0122.12.24388
MA0124.10.50249
MA0125.11.85521
MA0130.10
MA0131.10.3434
MA0132.10
MA0133.10
MA0135.14.89139
MA0136.10.0784355
MA0139.10.000237655
MA0140.10.373725
MA0141.11.96353
MA0142.10.45217
MA0143.10.958224
MA0144.10.0201057
MA0145.12.02058
MA0146.10.0032139
MA0147.10.00086697
MA0148.10.0821333
MA0149.10.106602
MA0062.29.19656e-05
MA0035.20.799364
MA0039.22.27868e-08
MA0138.20.0119021
MA0002.20.311441
MA0137.20.0449024
MA0104.21.80681e-05
MA0047.20.364577
MA0112.20.00547496
MA0065.20.235895
MA0150.10.0245807
MA0151.10
MA0152.10.590353
MA0153.18.27688
MA0154.10.00737324
MA0155.10.0385852
MA0156.10.00783235
MA0157.10.967544
MA0158.10
MA0159.10.11308
MA0160.10.321257
MA0161.10
MA0162.11.73612e-08
MA0163.17.89361e-07
MA0164.10.711194
MA0080.20.0048791
MA0018.20.105512
MA0099.20.235906
MA0079.20
MA0102.20.401893
MA0258.10.0552689
MA0259.10.00112806
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data