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DOID:1240

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Name:leukemia
Namespace:FANTOM
Definition:"A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells." [url:http://en.wikipedia.org/wiki/Leukemia]
Xrefs:
links:

ICD9CM:208
ICD9CM:208.9
MSH:D007938
NCI:C3161
SNOMEDCT_2010_1_31:154598008
SNOMEDCT_2010_1_31:188762002
SNOMEDCT_2010_1_31:188767008
SNOMEDCT_2010_1_31:190024009
SNOMEDCT_2010_1_31:190025005
SNOMEDCT_2010_1_31:190029004
SNOMEDCT_2010_1_31:190071003
SNOMEDCT_2010_1_31:255049003
SNOMEDCT_2010_1_31:87163000
SNOMEDCT_2010_1_31:93143009

UMLS_CUI:C0023418
Alt_id: DOID:9145

Ontology association
Each term has an is_a parent in the Disease Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to DISEASE ontologies.

link to ontology dataset
data


Parents

is_a:DOID:2531(hematologic cancer)



Children


is a:DOID:1036 (chronic leukemia),DOID:1037 (lymphoblastic leukemia),DOID:12603 (acute leukemia),DOID:8692 (myeloid leukemia)


Ontology Tree: Loaded from BioPortal

FF samples

Human (Homo sapiens)

  • 10399-106A3 (acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh))
  • 10400-106A4 (acute myeloid leukemia (FAB M5) cell line:THP-1 (revived))
  • 10405-106A9 (acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed))
  • 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
  • 10416-106C2 (chronic lymphocytic leukemia (T-CLL) cell line:SKW-3)
  • 10421-106C7 (adult T-cell leukemia cell line:ATN-1)
  • 10429-106D6 (acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL)
  • 10454-106G4 (chronic myelogenous leukemia cell line:K562)
  • 10455-106G5 (acute lymphoblastic leukemia (B-ALL) cell line:BALL-1)
  • 10464-106H5 (acute lymphoblastic leukemia (T-ALL) cell line:Jurkat)

... further results Mouse (Mus musculus)

  • 10399-106A3 (acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh))
  • 10400-106A4 (acute myeloid leukemia (FAB M5) cell line:THP-1 (revived))
  • 10405-106A9 (acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed))
  • 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
  • 10416-106C2 (chronic lymphocytic leukemia (T-CLL) cell line:SKW-3)
  • 10421-106C7 (adult T-cell leukemia cell line:ATN-1)
  • 10429-106D6 (acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL)
  • 10454-106G4 (chronic myelogenous leukemia cell line:K562)
  • 10455-106G5 (acute lymphoblastic leukemia (B-ALL) cell line:BALL-1)
  • 10464-106H5 (acute lymphoblastic leukemia (T-ALL) cell line:Jurkat)

... further results

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with DOID:1240 (leukemia), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
3.78e-103FFCP PHASE2:Hg19::chr6:135513595..135513617,+#_3b016bbf75b8d0aae2ccd0a938aa331dp4@MYB
3.78e-103FFCP PHASE1:Hg19::chr6:135513595..135513617,+#_3b016bbf75b8d0aae2ccd0a938aa331dp4@MYB
7.48e-96FFCP PHASE2:Hg19::chr12:58329776..58329791,-#_de170edf54466305f1ef07b8fbaa3466p3@ENST00000547492
7.48e-96FFCP PHASE1:Hg19::chr12:58329776..58329791,-#_de170edf54466305f1ef07b8fbaa3466p3@ENST00000547492
6.39e-95FFCP PHASE1:Hg19::chr16:29674970..29675007,+#_3b5137f05a3873cb4003a806e9cce1d8p4@SPN
6.39e-95FFCP PHASE2:Hg19::chr16:29674970..29675007,+#_3b5137f05a3873cb4003a806e9cce1d8p4@SPN
3.4e-94FFCP PHASE1:Hg19::chr6:68598314..68598325,-#_2c95962b21acf34a5695217b20dbcb8cp@chr6:68598314..68598325, -
3.4e-94FFCP PHASE2:Hg19::chr6:68598314..68598325,-#_2c95962b21acf34a5695217b20dbcb8cp@chr6:68598314..68598325, -
2.68e-92FFCP PHASE2:Hg19::chr12:58329793..58329806,-#_eb17f0825cf32b4062f85e5d6bd56b60p2@ENST00000547492
2.68e-92FFCP PHASE1:Hg19::chr12:58329793..58329806,-#_eb17f0825cf32b4062f85e5d6bd56b60p2@ENST00000547492
4.68e-91FFCP PHASE1:Hg19::chr6:68598272..68598298,-#_a003dbefa436770682067a2a3d403e04p@chr6:68598272..68598298, -
4.68e-91FFCP PHASE2:Hg19::chr6:68598272..68598298,-#_a003dbefa436770682067a2a3d403e04p@chr6:68598272..68598298, -
2.96e-89FFCP PHASE2:Hg19::chr6:68596384..68596400,-#_a1698cae91317db36b5031f8a7f7380ap@chr6:68596384..68596400, -
2.96e-89FFCP PHASE1:Hg19::chr6:68596384..68596400,-#_a1698cae91317db36b5031f8a7f7380ap@chr6:68596384..68596400, -
1.58e-86FFCP PHASE1:Mm9::chr11:102331415..102331424,-#_4f59dd18e104717a79d3a5dd3049fefdp9@Itga2b
1.58e-86FFCP PHASE2:Mm9::chr10:76688454..76688462,+#_4f59dd18e104717a79d3a5dd3049fefdp@chr10:76688454..76688462, +
1.58e-86FFCP PHASE1:Mm9::chr10:76688454..76688462,+#_4f59dd18e104717a79d3a5dd3049fefdp@chr10:76688454..76688462, +
1.58e-86FFCP PHASE2:Mm9::chr10:76688464..76688474,+#_4f59dd18e104717a79d3a5dd3049fefdp@chr10:76688464..76688474, +
1.58e-86FFCP PHASE1:Mm9::chr10:76688464..76688474,+#_4f59dd18e104717a79d3a5dd3049fefdp@chr10:76688464..76688474, +
1.58e-86FFCP PHASE2:Mm9::chr11:102331415..102331424,-#_4f59dd18e104717a79d3a5dd3049fefdp9@Itga2b
1.84e-86FFCP PHASE1:Hg19::chr12:58329762..58329773,-#_2fdfc0cab71767590bb07beb58380422p5@ENST00000547492
1.84e-86FFCP PHASE2:Hg19::chr12:58329762..58329773,-#_2fdfc0cab71767590bb07beb58380422p5@ENST00000547492
1.62e-85FFCP PHASE1:Hg19::chr6:135533394..135533403,+#_2ec16243574e23d40d5835b793f7b923p@chr6:135533394..135533403, +
1.62e-85FFCP PHASE2:Hg19::chr6:135533394..135533403,+#_2ec16243574e23d40d5835b793f7b923p@chr6:135533394..135533403, +
3.6e-85FFCP PHASE2:Hg19::chr6:68592986..68593000,-#_bde8bda59c30c868c51525369a683e5dp@chr6:68592986..68593000, -
3.6e-85FFCP PHASE1:Hg19::chr6:68592986..68593000,-#_bde8bda59c30c868c51525369a683e5dp@chr6:68592986..68593000, -
3.77e-85FFCP PHASE1:Hg19::chr6:68598245..68598268,-#_7cc31a5c760572801848310dc47bce2ap@chr6:68598245..68598268, -
3.77e-85FFCP PHASE2:Hg19::chr6:68598245..68598268,-#_7cc31a5c760572801848310dc47bce2ap@chr6:68598245..68598268, -
1.61e-84FFCP PHASE1:Hg19::chr6:68598507..68598519,-#_b163918b192f0096fce296b9757f90acp@chr6:68598507..68598519, -
1.61e-84FFCP PHASE2:Hg19::chr6:68598507..68598519,-#_b163918b192f0096fce296b9757f90acp@chr6:68598507..68598519, -
2.52e-84FFCP PHASE2:Hg19::chr6:68598587..68598598,-#_d048f13b3bb24475d4e683781d993ecdp@chr6:68598587..68598598, -
2.52e-84FFCP PHASE1:Hg19::chr6:68598587..68598598,-#_d048f13b3bb24475d4e683781d993ecdp@chr6:68598587..68598598, -
5.25e-84FFCP PHASE2:Hg19::chr16:29675010..29675041,+#_4d798d13addb274d38c5f8bc050cda6bp5@SPN
5.25e-84FFCP PHASE1:Hg19::chr16:29675010..29675041,+#_4d798d13addb274d38c5f8bc050cda6bp5@SPN
2.83e-80FFCP PHASE1:Hg19::chr19:695494..695510,-#_5a0c0dd7fb3fa55eec0104d3c5b506a8p3@PRSS57
2.83e-80FFCP PHASE2:Hg19::chr19:695494..695510,-#_5a0c0dd7fb3fa55eec0104d3c5b506a8p3@PRSS57
5.88e-80FFCP PHASE2:Hg19::chr11:33913475..33913549,-#_aef20964126286b005630e59adb74ed9p5@LMO2
5.88e-80FFCP PHASE1:Hg19::chr11:33913475..33913549,-#_aef20964126286b005630e59adb74ed9p5@LMO2
1.29e-79FFCP PHASE1:Hg19::chr6:68593536..68593560,-#_b541f1de51fa1555575d7dbfcb4bf106p@chr6:68593536..68593560, -
1.29e-79FFCP PHASE2:Hg19::chr6:68591611..68591627,-#_b541f1de51fa1555575d7dbfcb4bf106p@chr6:68591611..68591627, -
1.29e-79FFCP PHASE1:Hg19::chr6:68591611..68591627,-#_b541f1de51fa1555575d7dbfcb4bf106p@chr6:68591611..68591627, -
1.29e-79FFCP PHASE2:Hg19::chr6:68593536..68593560,-#_b541f1de51fa1555575d7dbfcb4bf106p@chr6:68593536..68593560, -
2.09e-79FFCP PHASE1:Hg19::chr6:68596826..68596859,-#_dcdd16cfd9b83b38f8f16e3ab13a56e1p@chr6:68596826..68596859, -
2.09e-79FFCP PHASE2:Hg19::chr6:68596826..68596859,-#_dcdd16cfd9b83b38f8f16e3ab13a56e1p@chr6:68596826..68596859, -
2.09e-79FFCP PHASE2:Hg19::chr6:68596698..68596715,-#_dcdd16cfd9b83b38f8f16e3ab13a56e1p@chr6:68596698..68596715, -
2.09e-79FFCP PHASE1:Hg19::chr6:68597599..68597612,-#_dcdd16cfd9b83b38f8f16e3ab13a56e1p@chr6:68597599..68597612, -
2.09e-79FFCP PHASE1:Hg19::chr6:68596698..68596715,-#_dcdd16cfd9b83b38f8f16e3ab13a56e1p@chr6:68596698..68596715, -
2.09e-79FFCP PHASE2:Hg19::chr6:68597599..68597612,-#_dcdd16cfd9b83b38f8f16e3ab13a56e1p@chr6:68597599..68597612, -
1.93e-78FFCP PHASE2:Hg19::chr6:135502472..135502489,+#_0bdc3d6479a106e0d642eba2834d2b14p3@MYB
1.93e-78FFCP PHASE1:Hg19::chr6:135502472..135502489,+#_0bdc3d6479a106e0d642eba2834d2b14p3@MYB
2.09e-77FFCP PHASE2:Hg19::chr1:202129105..202129140,-#_d289c35e85c28529698e69239db691a3p2@PTPN7
2.09e-77FFCP PHASE1:Hg19::chr1:202129105..202129140,-#_d289c35e85c28529698e69239db691a3p2@PTPN7
7.47e-77FFCP PHASE1:Hg19::chr11:17297848..17297868,+#_3897ce3a5e4bc599ddf6a959f3a140fbp9@NUCB2
7.47e-77FFCP PHASE2:Hg19::chr11:17297848..17297868,+#_3897ce3a5e4bc599ddf6a959f3a140fbp9@NUCB2
1.06e-74FFCP PHASE1:Hg19::chr6:68595369..68595417,-#_d8e042452dc985d7145220aa9cd7d9dcp@chr6:68595369..68595417, -
1.06e-74FFCP PHASE2:Hg19::chr6:68593520..68593534,-#_d8e042452dc985d7145220aa9cd7d9dcp@chr6:68593520..68593534, -
1.06e-74FFCP PHASE1:Hg19::chr6:68593520..68593534,-#_d8e042452dc985d7145220aa9cd7d9dcp@chr6:68593520..68593534, -
1.06e-74FFCP PHASE2:Hg19::chr6:68595369..68595417,-#_d8e042452dc985d7145220aa9cd7d9dcp@chr6:68595369..68595417, -
1.7e-74FFCP PHASE1:Hg19::chr6:68596783..68596797,-#_0911214e5fef66bd1b44f37dbbb99830p@chr6:68596783..68596797, -
1.7e-74FFCP PHASE2:Hg19::chr6:68596343..68596355,-#_0911214e5fef66bd1b44f37dbbb99830p@chr6:68596343..68596355, -
1.7e-74FFCP PHASE2:Hg19::chr6:68596783..68596797,-#_0911214e5fef66bd1b44f37dbbb99830-, p@chr6:68596783..68596797
1.7e-74FFCP PHASE1:Hg19::chr6:68596343..68596355,-#_0911214e5fef66bd1b44f37dbbb99830p@chr6:68596343..68596355, -
6.82e-72FFCP PHASE2:Hg19::chr3:18020982..18021001,+#_309d32364d6261e7826f714b9642f0abp@chr3:18020982..18021001, +
6.82e-72FFCP PHASE1:Hg19::chr3:18020982..18021001,+#_309d32364d6261e7826f714b9642f0abp@chr3:18020982..18021001, +
1.36e-71FFCP PHASE1:Hg19::chr22:50523908..50523925,-#_b795c5eb1f107dd59e1175c561e88221p8@MLC1
1.36e-71FFCP PHASE2:Hg19::chr22:50523908..50523925,-#_b795c5eb1f107dd59e1175c561e88221p8@MLC1
1.62e-71FFCP PHASE1:Hg19::chr19:695467..695482,-#_660c7fbcb2045bf4c8ea016d3cf37580p2@PRSS57
1.62e-71FFCP PHASE2:Hg19::chr19:695467..695482,-#_660c7fbcb2045bf4c8ea016d3cf37580p2@PRSS57
5.58e-71FFCP PHASE2:Hg19::chr6:135516978..135516993,+#_0a0febb1a555fc1c8a3746dd8f038f67p7@MYB
5.58e-71FFCP PHASE1:Hg19::chr6:135516978..135516993,+#_0a0febb1a555fc1c8a3746dd8f038f67p7@MYB
8.11e-71FFCP PHASE1:Hg19::chr6:68598984..68598997,-#_2d836f82f6de1b961f7fbc55bc331de3p2@uc003pes.1, p2@uc003pet.1
8.11e-71FFCP PHASE2:Hg19::chr6:68598984..68598997,-#_2d836f82f6de1b961f7fbc55bc331de3p2@uc003pes.1, p2@uc003pet.1
2.97e-70FFCP PHASE2:Hg19::chr6:68596289..68596302,-#_7f16ea159dc368696d4824bc2d899b30p@chr6:68596289..68596302, -
2.97e-70FFCP PHASE1:Hg19::chr6:68596289..68596302,-#_7f16ea159dc368696d4824bc2d899b30p@chr6:68596289..68596302, -
3.0e-70FFCP PHASE1:Hg19::chr1:202130702..202130728,-#_9b0ee045f0da192d3338396b840ecc81p3@PTPN7
3.0e-70FFCP PHASE2:Hg19::chr1:202130702..202130728,-#_9b0ee045f0da192d3338396b840ecc81p3@PTPN7
6.05e-70FFCP PHASE1:Hg19::chr6:68599042..68599067,-#_a3519b67f79d798714a9296340ea1cadp1@uc003pes.1, p1@uc003pet.1
6.05e-70FFCP PHASE2:Hg19::chr6:68599042..68599067,-#_a3519b67f79d798714a9296340ea1cadp1@uc003pes.1, p1@uc003pet.1
8.49e-70FFCP PHASE2:Hg19::chr6:68592948..68592958,-#_421152d995d6919610685e29e63536a1p@chr6:68592948..68592958, -
8.49e-70FFCP PHASE1:Hg19::chr6:68592948..68592958,-#_421152d995d6919610685e29e63536a1p@chr6:68592948..68592958, -
8.92e-70FFCP PHASE1:Hg19::chr6:68598534..68598555,-#_14abc2887998125bd622ecfee0886f04p@chr6:68598534..68598555, -
8.92e-70FFCP PHASE2:Hg19::chr6:68598534..68598555,-#_14abc2887998125bd622ecfee0886f04p@chr6:68598534..68598555, -
9.84e-70FFCP PHASE2:Hg19::chr6:68593264..68593275,-#_2230b51a397e4fea1899b7c33e138801p@chr6:68593264..68593275, -
9.84e-70FFCP PHASE1:Hg19::chr6:68593264..68593275,-#_2230b51a397e4fea1899b7c33e138801p@chr6:68593264..68593275, -
1.35e-69FFCP PHASE1:Hg19::chr6:68597438..68597450,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68597438..68597450, -
1.35e-69FFCP PHASE2:Hg19::chr6:68593587..68593600,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68593587..68593600, -
1.35e-69FFCP PHASE2:Hg19::chr6:68597438..68597450,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68597438..68597450, -
1.35e-69FFCP PHASE1:Hg19::chr6:68593587..68593600,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68593587..68593600, -
1.35e-69FFCP PHASE2:Hg19::chr6:68593250..68593259,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68593250..68593259, -
1.35e-69FFCP PHASE1:Hg19::chr6:68593250..68593259,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68593250..68593259, -
1.35e-69FFCP PHASE2:Hg19::chr6:68596757..68596769,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68596757..68596769, -
1.35e-69FFCP PHASE1:Hg19::chr6:68596757..68596769,-#_65669b8918ba69bf8f73b14b1fe4c532p@chr6:68596757..68596769, -
4.05e-69FFCP PHASE1:Hg19::chr8:130560752..130560768,-#_4ae59d82190171b6d556037d8d0d87dfp@chr8:130560752..130560768, -
4.05e-69FFCP PHASE2:Hg19::chr8:130560752..130560768,-#_4ae59d82190171b6d556037d8d0d87dfp@chr8:130560752..130560768, -
1.38e-67FFCP PHASE1:Hg19::chr6:135526382..135526388,+#_5e234e4e5108e58d4777282dd1510b34p@chr6:135526382..135526388, +
1.38e-67FFCP PHASE2:Hg19::chr6:135526382..135526388,+#_5e234e4e5108e58d4777282dd1510b34p@chr6:135526382..135526388, +
3.05e-67FFCP PHASE2:Hg19::chr16:89043605..89043625,-#_d0546a37882c3c9167181a0ab22af388p6@CBFA2T3
3.05e-67FFCP PHASE1:Hg19::chr16:89043605..89043625,-#_d0546a37882c3c9167181a0ab22af388p6@CBFA2T3
7.28e-67FFCP PHASE2:Hg19::chr12:58329689..58329704,-#_eee80096774b4903575a992a89c96248p4@ENST00000547492
7.28e-67FFCP PHASE1:Hg19::chr12:58329689..58329704,-#_eee80096774b4903575a992a89c96248p4@ENST00000547492