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UBERON:0007100

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Name:primary circulatory organ
Namespace:FANTOM
Definition:"A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood[GO]." [GO:0007507]
Xrefs:
links:

ANISEED:1235302
FBbt:00003154
[1]

TADS:0000147
Synonyms: "adult heart" RELATED [FBbt:00003154]
"cardiac pump" EXACT []
"cardiac structure" RELATED []
"dorsal tube" NARROW [Wikipedia:Heart]
"heart" NARROW [GO:0007507]
"heart or heart like organ" EXACT []
Comments:editor note: we need to find the appropriate GO process to use for the definition - 'blood circulation' may not apply to invertebrates; 'circulatory system process' is circular. Note we cannot use a part_of-based definition as this results in the iris and all vascular elements being categorized as circulatory organs. Taxon notes: note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. "The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian". Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis. Gene notes: Bmp, Nkx, Gata
Subset: grouping_class

Ontology association
Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.

link to ontology dataset
data


Parents

is_a:UBERON:0015228(circulatory organ)
part_of:UBERON:0001009(circulatory system)



Children

is a:UBERON:0000948 (heart)
part of:CL:0000746 (cardiac muscle cell),CL:0002494 (cardiocyte)

Ontology Tree: Loaded from BioPortal


FF samples
It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0007100 (primary circulatory organ), sorted by p-values
Analyst: Hideya Kawaji

link to source dataset
human : data
mouse : data


P-valueFFCPShort description
1.09e-81FFCP PHASE1:Mm9::chr4:147375434..147375447,+#_51964097263442c9eecfc750d638af3ep@chr4:147375434..147375447, +
1.09e-81FFCP PHASE2:Mm9::chr4:147375434..147375447,+#_51964097263442c9eecfc750d638af3ep@chr4:147375434..147375447, +
1.09e-81FFCP PHASE1:Mm9::chr1:137747392..137747402,-#_51964097263442c9eecfc750d638af3ep@chr1:137747392..137747402, -
1.09e-81FFCP PHASE2:Mm9::chr1:137747392..137747402,-#_51964097263442c9eecfc750d638af3ep@chr1:137747392..137747402, -
1.09e-81FFCP PHASE1:Mm9::chr9:24549775..24549776,-#_51964097263442c9eecfc750d638af3ep@chr9:24549775..24549776, -
1.09e-81FFCP PHASE2:Mm9::chr9:24549775..24549776,-#_51964097263442c9eecfc750d638af3ep@chr9:24549775..24549776, -
5.69e-81FFCP PHASE2:Hg19::chr17:77019002..77019027,+#_653e72ab25b5d33370f1abf2903c44fdp@chr17:77019002..77019027, +
5.69e-81FFCP PHASE1:Hg19::chr17:77019002..77019027,+#_653e72ab25b5d33370f1abf2903c44fdp@chr17:77019002..77019027, +
2.21e-79FFCP PHASE1:Hg19::chr17:77018953..77018966,+#_10881b560d1ebe029bb42fde521acc61p@chr17:77018953..77018966, +
2.21e-79FFCP PHASE2:Hg19::chr17:77018953..77018966,+#_10881b560d1ebe029bb42fde521acc61p@chr17:77018953..77018966, +
1.88e-78FFCP PHASE2:Mm9::chr4:140980456..140980463,+#_a6e8a2c1f45de514e93b752b8ba5f4ecp@chr4:140980456..140980463, +
1.88e-78FFCP PHASE1:Mm9::chr4:140980456..140980463,+#_a6e8a2c1f45de514e93b752b8ba5f4ecp@chr4:140980456..140980463, +
1.92e-77FFCP PHASE1:Mm9::chr12:113728951..113728965,+#_77d4c4d9af3217b9c97dce7da1dc578cp@chr12:113728951..113728965, +
1.92e-77FFCP PHASE2:Mm9::chr12:113728951..113728965,+#_77d4c4d9af3217b9c97dce7da1dc578cp@chr12:113728951..113728965, +
1.92e-77FFCP PHASE2:Mm9::chr1:137737483..137737497,-#_77d4c4d9af3217b9c97dce7da1dc578cp@chr1:137737483..137737497, -
1.92e-77FFCP PHASE1:Mm9::chr1:137737483..137737497,-#_77d4c4d9af3217b9c97dce7da1dc578cp@chr1:137737483..137737497, -
2.14e-77FFCP PHASE2:Mm9::chr4:147375200..147375220,+#_8b0f994f15e8a19d643bd690f0d14ce7p@chr4:147375200..147375220, +
2.14e-77FFCP PHASE1:Mm9::chr19:36187511..36187515,-#_8b0f994f15e8a19d643bd690f0d14ce7p@chr19:36187511..36187515, -
2.14e-77FFCP PHASE1:Mm9::chr4:147375200..147375220,+#_8b0f994f15e8a19d643bd690f0d14ce7p@chr4:147375200..147375220, +
2.14e-77FFCP PHASE2:Mm9::chr19:36187511..36187515,-#_8b0f994f15e8a19d643bd690f0d14ce7p@chr19:36187511..36187515, -
8.14e-77FFCP PHASE2:Mm9::chr19:36193772..36193793,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr19:36193772..36193793, -
8.14e-77FFCP PHASE1:Mm9::chr14:55579265..55579297,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55579265..55579297, -
8.14e-77FFCP PHASE1:Mm9::chr14:55581579..55581620,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55581579..55581620, -
8.14e-77FFCP PHASE1:Mm9::chr14:55584197..55584239,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55584197..55584239, -
8.14e-77FFCP PHASE1:Mm9::chr14:55584272..55584298,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55584272..55584298, -
8.14e-77FFCP PHASE1:Mm9::chr14:55584663..55584731,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55584663..55584731, -
8.14e-77FFCP PHASE1:Mm9::chr14:55586837..55586880,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55586837..55586880, -
8.14e-77FFCP PHASE2:Mm9::chr4:147375901..147375913,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr4:147375901..147375913, +
8.14e-77FFCP PHASE1:Mm9::chr15:88850827..88850850,+#_0ebbd06366a73ebcea0f8bc6cb089866p2@Mov10l1
8.14e-77FFCP PHASE1:Mm9::chr19:36193772..36193793,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr19:36193772..36193793, -
8.14e-77FFCP PHASE1:Mm9::chr1:137743272..137743307,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137743272..137743307, +
8.14e-77FFCP PHASE1:Mm9::chr1:137744333..137744352,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744333..137744352, -
8.14e-77FFCP PHASE1:Mm9::chr1:137744550..137744565,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744550..137744565, +
8.14e-77FFCP PHASE1:Mm9::chr1:137744611..137744621,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744611..137744621, +
8.14e-77FFCP PHASE1:Mm9::chr1:137744636..137744654,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744636..137744654, +
8.14e-77FFCP PHASE1:Mm9::chr1:137744668..137744681,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744668..137744681, -
8.14e-77FFCP PHASE1:Mm9::chr1:137745434..137745445,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137745434..137745445, +
8.14e-77FFCP PHASE1:Mm9::chr1:137747289..137747313,+#_0ebbd06366a73ebcea0f8bc6cb089866+, p@chr1:137747289..137747313
8.14e-77FFCP PHASE1:Mm9::chr1:137747382..137747385,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137747382..137747385, -
8.14e-77FFCP PHASE1:Mm9::chr1:137747953..137747967,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137747953..137747967, -
8.14e-77FFCP PHASE2:Mm9::chr14:55563577..55563611,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55563577..55563611, -
8.14e-77FFCP PHASE2:Mm9::chr14:55565785..55565833,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55565785..55565833, -
8.14e-77FFCP PHASE2:Mm9::chr14:55568737..55568746,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55568737..55568746, -
8.14e-77FFCP PHASE2:Mm9::chr14:55568790..55568803,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55568790..55568803, -
8.14e-77FFCP PHASE2:Mm9::chr14:55568937..55568988,-#_0ebbd06366a73ebcea0f8bc6cb089866-, p@chr14:55568937..55568988
8.14e-77FFCP PHASE2:Mm9::chr14:55571909..55571953,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55571909..55571953, -
8.14e-77FFCP PHASE2:Mm9::chr14:55572120..55572173,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55572120..55572173, +
8.14e-77FFCP PHASE2:Mm9::chr14:55579265..55579297,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55579265..55579297, -
8.14e-77FFCP PHASE2:Mm9::chr14:55581579..55581620,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55581579..55581620, -
8.14e-77FFCP PHASE2:Mm9::chr14:55584197..55584239,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55584197..55584239, -
8.14e-77FFCP PHASE2:Mm9::chr14:55584272..55584298,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55584272..55584298, -
8.14e-77FFCP PHASE2:Mm9::chr14:55584663..55584731,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55584663..55584731, -
8.14e-77FFCP PHASE2:Mm9::chr14:55586837..55586880,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55586837..55586880, -
8.14e-77FFCP PHASE2:Mm9::chr15:88850827..88850850,+#_0ebbd06366a73ebcea0f8bc6cb089866p2@Mov10l1
8.14e-77FFCP PHASE1:Mm9::chr4:147375901..147375913,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr4:147375901..147375913, +
8.14e-77FFCP PHASE1:Mm9::chr5:120286706..120286736,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr5:120286706..120286736, +
8.14e-77FFCP PHASE1:Mm9::chr11:58815923..58815951,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr11:58815923..58815951, -
8.14e-77FFCP PHASE1:Mm9::chr11:65461897..65461929,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr11:65461897..65461929, -
8.14e-77FFCP PHASE2:Mm9::chr5:120286706..120286736,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr5:120286706..120286736, +
8.14e-77FFCP PHASE2:Mm9::chr1:137743272..137743307,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137743272..137743307, +
8.14e-77FFCP PHASE2:Mm9::chr1:137744333..137744352,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744333..137744352, -
8.14e-77FFCP PHASE2:Mm9::chr1:137744550..137744565,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744550..137744565, +
8.14e-77FFCP PHASE2:Mm9::chr1:137744611..137744621,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744611..137744621, +
8.14e-77FFCP PHASE2:Mm9::chr1:137744636..137744654,+#_0ebbd06366a73ebcea0f8bc6cb089866+, p@chr1:137744636..137744654
8.14e-77FFCP PHASE2:Mm9::chr1:137744668..137744681,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137744668..137744681, -
8.14e-77FFCP PHASE2:Mm9::chr1:137745434..137745445,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137745434..137745445, +
8.14e-77FFCP PHASE2:Mm9::chr1:137747289..137747313,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137747289..137747313, +
8.14e-77FFCP PHASE2:Mm9::chr1:137747382..137747385,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137747382..137747385, -
8.14e-77FFCP PHASE2:Mm9::chr1:137747953..137747967,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr1:137747953..137747967, -
8.14e-77FFCP PHASE2:Mm9::chr11:58815923..58815951,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr11:58815923..58815951, -
8.14e-77FFCP PHASE2:Mm9::chr11:65461897..65461929,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr11:65461897..65461929, -
8.14e-77FFCP PHASE1:Mm9::chr14:55563577..55563611,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55563577..55563611, -
8.14e-77FFCP PHASE1:Mm9::chr14:55565785..55565833,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55565785..55565833, -
8.14e-77FFCP PHASE1:Mm9::chr14:55568737..55568746,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55568737..55568746, -
8.14e-77FFCP PHASE1:Mm9::chr14:55568790..55568803,-#_0ebbd06366a73ebcea0f8bc6cb089866-, p@chr14:55568790..55568803
8.14e-77FFCP PHASE1:Mm9::chr14:55568937..55568988,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55568937..55568988, -
8.14e-77FFCP PHASE1:Mm9::chr14:55571909..55571953,-#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55571909..55571953, -
8.14e-77FFCP PHASE1:Mm9::chr14:55572120..55572173,+#_0ebbd06366a73ebcea0f8bc6cb089866p@chr14:55572120..55572173, +
1.2e-73FFCP PHASE1:Mm9::chr1:137742152..137742184,-#_fe40d489e19641fa791cef9be436ab32p@chr1:137742152..137742184, -
1.2e-73FFCP PHASE2:Mm9::chr1:137742152..137742184,-#_fe40d489e19641fa791cef9be436ab32p@chr1:137742152..137742184, -
1.46e-72FFCP PHASE1:Mm9::chr7:4473478..4473505,-#_465d556be13caa16245407d1aa2d5e38p2@Tnni3
1.46e-72FFCP PHASE2:Mm9::chr1:137742470..137742481,+#_465d556be13caa16245407d1aa2d5e38p@chr1:137742470..137742481, +
1.46e-72FFCP PHASE1:Mm9::chr14:55577329..55577367,-#_465d556be13caa16245407d1aa2d5e38p@chr14:55577329..55577367, -
1.46e-72FFCP PHASE2:Mm9::chr16:5431481..5431510,+#_465d556be13caa16245407d1aa2d5e38p@chr16:5431481..5431510, +
1.46e-72FFCP PHASE2:Mm9::chr7:4473478..4473505,-#_465d556be13caa16245407d1aa2d5e38p2@Tnni3
1.46e-72FFCP PHASE1:Mm9::chr16:5431481..5431510,+#_465d556be13caa16245407d1aa2d5e38p@chr16:5431481..5431510, +
1.46e-72FFCP PHASE1:Mm9::chr1:137742470..137742481,+#_465d556be13caa16245407d1aa2d5e38p@chr1:137742470..137742481, +
1.46e-72FFCP PHASE2:Mm9::chr14:55577329..55577367,-#_465d556be13caa16245407d1aa2d5e38p@chr14:55577329..55577367, -
1.63e-72FFCP PHASE1:Mm9::chr5:58108164..58108178,+#_60735c988619e5db959bc6655406d1ecp@chr5:58108164..58108178, +
1.63e-72FFCP PHASE2:Mm9::chr10:53062244..53062249,+#_60735c988619e5db959bc6655406d1ecp@chr10:53062244..53062249, +
1.63e-72FFCP PHASE2:Mm9::chr5:58108164..58108178,+#_60735c988619e5db959bc6655406d1ecp@chr5:58108164..58108178, +
1.63e-72FFCP PHASE2:Mm9::chr2:17382210..17382221,-#_60735c988619e5db959bc6655406d1ecp5@Nebl
1.63e-72FFCP PHASE2:Mm9::chr2:113880065..113880076,+#_60735c988619e5db959bc6655406d1ecp1@ENSMUST00000154140
1.63e-72FFCP PHASE2:Mm9::chr16:38713504..38713520,-#_60735c988619e5db959bc6655406d1ecp11@Arhgap31
1.63e-72FFCP PHASE1:Mm9::chr10:53062244..53062249,+#_60735c988619e5db959bc6655406d1ecp@chr10:53062244..53062249, +
1.63e-72FFCP PHASE2:Mm9::chr19:36193739..36193752,-#_60735c988619e5db959bc6655406d1ecp@chr19:36193739..36193752, -
1.63e-72FFCP PHASE1:Mm9::chr2:17382210..17382221,-#_60735c988619e5db959bc6655406d1ecp5@Nebl
1.63e-72FFCP PHASE1:Mm9::chr16:38713504..38713520,-#_60735c988619e5db959bc6655406d1ecp11@Arhgap31
1.63e-72FFCP PHASE1:Mm9::chr19:36193739..36193752,-#_60735c988619e5db959bc6655406d1ecp@chr19:36193739..36193752, -
1.63e-72FFCP PHASE1:Mm9::chr2:113880065..113880076,+#_60735c988619e5db959bc6655406d1ecp1@ENSMUST00000154140