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MCL coexpression mm9:1035

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:62991132..62991135,+p@chr10:62991132..62991135
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Mm9::chr10:63321598..63321602,+p@chr10:63321598..63321602
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Mm9::chr10:63480516..63480520,+p@chr10:63480516..63480520
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Mm9::chr10:63553671..63553676,+p@chr10:63553671..63553676
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Mm9::chr10:63777271..63777275,+p@chr10:63777271..63777275
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Mm9::chr12:55963956..55963984,+p1@uc007nny.1
Mm9::chr2:30851191..30851242,+p3@Usp20


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004221ubiquitin thiolesterase activity0.0229606092149236
GO:0004843ubiquitin-specific protease activity0.0229606092149236
GO:0019783small conjugating protein-specific protease activity0.0229606092149236
GO:0004197cysteine-type endopeptidase activity0.0229606092149236
GO:0016790thiolester hydrolase activity0.0229606092149236
GO:0006511ubiquitin-dependent protein catabolic process0.0229606092149236
GO:0043632modification-dependent macromolecule catabolic process0.0229606092149236
GO:0019941modification-dependent protein catabolic process0.0229606092149236
GO:0051603proteolysis involved in cellular protein catabolic process0.0229606092149236
GO:0044257cellular protein catabolic process0.0229606092149236
GO:0008234cysteine-type peptidase activity0.0253109077959788
GO:0030163protein catabolic process0.0263655289541445
GO:0044265cellular macromolecule catabolic process0.0298307127595464
GO:0043285biopolymer catabolic process0.0298307127595464
GO:0009057macromolecule catabolic process0.0351942146496466
GO:0044248cellular catabolic process0.0438923282017568
GO:0004175endopeptidase activity0.0438923282017568
GO:0006512ubiquitin cycle0.0438923282017568



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
primary circulatory organ2.11e-1218
heart2.11e-1218
primitive heart tube2.11e-1218
primary heart field2.11e-1218
anterior lateral plate mesoderm2.11e-1218
heart tube2.11e-1218
heart primordium2.11e-1218
cardiac mesoderm2.11e-1218
cardiogenic plate2.11e-1218
heart rudiment2.11e-1218
compound organ9.70e-1043
cardiovascular system1.09e-0923
circulatory system1.09e-0923


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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